OBATA HIDEAKI 小幡英章

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OBATA Hidaaki 小幡英章

OBATA Hideaki 小幡英章

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Researcher Number	20302482
Other IDs
External Links
Affiliation (Current)	2025: 埼玉医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 埼玉医科大学, 医学部, 教授 2015 – 2020: 福島県立医科大学, 医学部, 教授 2012 – 2014: 群馬大学, 医学(系)研究科(研究院), 准教授 2013: 群馬大学, 大学院医学系研究科, 准教授 2005 – 2011: 群馬大学, 医学部, 講師 1999 – 2001: 群馬大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Anesthesiology / Anesthesiology/Resuscitation studies / Basic Section 55050:Anesthesiology-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Anesthesiology/Resuscitation studies Except Principal Investigator Basic Section 55050:Anesthesiology-related / Basic Section 56020:Orthopedics-related / Community health/Gerontological nurisng / Clinical nursing / Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator ノルアドレナリン / ラット / 脊髄 / セロトニン / 内因性鎮痛系 / 下行性抑制系 / 神経障害性疼痛 / 腹側被蓋野 / Allodynia / Neuropathic pain … More / アロディニア / 側坐核 / 腹側被害野 / ドパミン / グルタミン酸トランスポーター / 反復社会的敗北モデル / 反復社会的敗北ストレス / 青斑核 / P2X7受容体 / P2X受容体 / 脳脊髄 / PET / ミクログリア / TSPO PETリガンド / [11C]PBR28 / 慢性痛 / Postoperative pain / Hyperalgesia / Astrocyte / Microglia / Spinal glia / アストロ際と痛覚過敏 / 髄グリア / 神経因性疼痛 / 術後痛 / 痛覚過敏 / アストロサイト / マイクログリア / 脊髄グリア / Muscarinic receptor antagonists / 5-HT_2 receptor agonists / Intrathecally administration / Serotonin / 5-HT_2レセプター作動薬 / ムスカリン受容体 / 5-HT_2受容体作動薬 / 髄腔内投与 / ニューロパシックペイン / 内因性鎮痛 / α2受容体 / グリア / 薬剤可塑性 / ノルアドレナリソ / マイクロダイアライシス … More Except Principal Investigator 下行性抑制系 / 青斑核 / 慢性痛 / 前頭前野 / ノルアドレナリン / 神経障害性疼痛 / 内因性鎮痛機構 / 内因性鎮痛 / ドパミンシステム / ストレス負荷 / 鎮痛薬 / 下行性疼痛抑制系 / 前頭前皮質 / DREADD / デュロキセチン / ガバペンチノイド / アストロサイト / 下行性抑制 / 疼痛 / 質向上 / 介護施設 / ケア基準 / 生活の質 / 慢性疼痛 / 長期療養 / ガイドライン / アセスメント / 介護 / 長期ケア / 高齢者 / 看護 / 疼痛管理 / FOLFOX療法 / 自律の体験 / 客観指標 / 主観評価 / アセスメント指標 / エルプラット / Oxaliplatin / 末梢神経障害 / 体験 / がん化学療法 / 評価指標 / 神経伝達速度 / 質的研究 / オキサリプラチン / 大腸がん / 持続性末梢神経障害 / 抗がん剤 / 再生医療 / 静脈麻酔薬 / 再生軸索 / 神経成長円錐 / グリア / 神経因性疼痛 / 重粒子線 / アルコール / 感覚障害 / ニューロメータ / 高濃度局所麻酔薬 / 感覚域値 / 神経障害 / 三叉神経痛 / テトラカイン / 局所麻酔薬 Less

内因性鎮痛の減弱は慢性痛の原因となり得るか？ーADHDでの検討ーPrincipal Investigator
- Principal Investigator
  
  小幡英章
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Saitama Medical University
ストレス負荷に伴う難治性疼痛-ドパミンの放出と下行性疼痛抑制系機能-
- Principal Investigator
  
  関口美穂
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Fukushima Medical University
The roles of prefrontal cortex on the endogenous analgesic systems
- Principal Investigator
  
  須藤貴史
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Gunma University
中脳辺縁ドパミン神経系の鎮痛機序とその可塑性に関する研究Principal Investigator
- Principal Investigator
  
  小幡英章
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Saitama Medical University
The relationship between the alteration of the locus coeruleus after peripheral nerve injury and the efficacy of analgesic drugs.
- Principal Investigator
  
  Suto Takashi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Gunma University
社会的心理ストレスによる神経障害性疼痛治療薬の鎮痛効果減弱機序についての研究
- Principal Investigator
  
  林田健一郎
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Akita University
A study to visualize chronic pain by cerebrospinal microglial imaging by the PETPrincipal Investigator
- Principal Investigator
  
  Obata Hideaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Fukushima Medical University
Effect of socio-psychological stress on endogenous analgesiaPrincipal Investigator
- Principal Investigator
  
  OBATA HIDEAKI
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology
- Research Institution
  Fukushima Medical University
The role of the descending inhibitory system in endogenous analgesiaPrincipal Investigator
- Principal Investigator
  
  Obata Hideaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology
- Research Institution
  Fukushima Medical University
  Gunma University
Pharmacological mechanisms of locus coeruleus activation -recruitment of descending inhibition for treatment of neuropathic pain-Principal Investigator
- Principal Investigator
  
  OBATA Hideaki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Gunma University
Mechanisms of effective drugs for management of neuropathic pain relationship between activation of descending inhibitory systems and pharmacologic plasticityPrincipal Investigator
- Principal Investigator
  
  OBATA Hideaki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology
- Research Institution
  Gunma University
Development of chronic pain management standards
- Principal Investigator
  
  TAKAI Yukari
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Community health/Gerontological nurisng
- Research Institution
  The University of Tokyo
  Gunma University
Development of a comprehensive care model using assessment indices for colorectal cancer patients with intractable peripheral neuropathy
- Principal Investigator
  
  KANDA Kiyoko
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical nursing
- Research Institution
  Gunma University
Pharmacologic plasticity of analgesic drugs in neuropathic pain states-measurement with monoamines in the spinal cord-Principal Investigator
- Principal Investigator
  
  OBATA Hideaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Gunma University
マイクロイオンビームによる神経障害性疼痛モデルの作成と中枢神経反応の解析
- Principal Investigator
  
  後藤文夫
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Gunma University
Possible involvement of activation of spinal glia with chronic painPrincipal Investigator
- Principal Investigator
  
  OBATA Hideaki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Gunma University
The mechanism of 5-HT receptor agonists for inhibitory effect in neuropathic painPrincipal Investigator
- Principal Investigator
  
  OBATA Hideaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Gunma University
高濃度局所麻酔薬を用いた難治性疼痛の治療法に関する研究
- Principal Investigator
  
  後藤文夫
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Gunma University

[Book] 麻酔科医のための周術期疼痛管理2014
- Author(s)
  小幡英章、斎藤繁
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-24659691
[Book] 麻酔科医のための周術期の疼痛管理2014
- Author(s)
  小幡英章　齋藤繁
- Total Pages
  8
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-24659691
[Book] 痛みの薬物治療2013
- Author(s)
  小幡英章
- Total Pages
  7
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-24659691
[Book] 痛みの薬物療法2013
- Author(s)
  小幡英章
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-24659691
[Book] 臨床麻酔2012
- Author(s)
  木村雅文, 小幡英章
- Total Pages
  6
- Publisher
  トラマドール
- Data Source
  KAKENHI-PROJECT-24659691
[Book] 臨床麻酔2012
- Author(s)
  木村雅文, 小幡英章
- Total Pages
  7
- Publisher
  術後鎮痛の薬理学的研究
- Data Source
  KAKENHI-PROJECT-24659691
[Book] Lisa2012
- Author(s)
  小幡英章
- Total Pages
  6
- Publisher
  痛みのバイオロジー　下行性制御：抑制と促進
- Data Source
  KAKENHI-PROJECT-23390373
[Book] Lisa2012
- Author(s)
  小幡英章
- Total Pages
  5
- Publisher
  痛みのバイオロジー, 下行性制御：抑制と促進
- Data Source
  KAKENHI-PROJECT-24659691
[Book] 神経障害性疼痛(真下節編)2011
- Author(s)
  小幡英章、齋藤繁
- Total Pages
  8
- Publisher
  克誠堂出版社
- Data Source
  KAKENHI-PROJECT-23390373
[Book] α2受容体をターゲットにした慢性疼痛の治療2008
- Author(s)
  小幡英章
- Total Pages
  11
- Publisher
  真興交易図書出版部、ペインクリニックVOL.29, No.2
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591613
[Book] α2受容体をターゲットにした慢性疼痛の治療2008
- Author(s)
  小幡英章
- Total Pages
  11
- Publisher
  真興交易図書出版部、ペインクリニックVOL.29,No.2
- Data Source
  KAKENHI-PROJECT-17591613
[Book] ペインクリニシャンのための痛み診療のコツと落とし穴、宮崎東洋編2007
- Author(s)
  小幡英章
- Total Pages
  2
- Publisher
  中山書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591613
[Book] ペインクリニシャンのための痛み診療のコツと落とし穴、宮崎東洋編2007
- Author(s)
  小幡英章
- Total Pages
  2
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-17591613
[Book] 脊髄後角のα2受容体-その機能と下行性抑制系-、麻酔増刊VOL.562007
- Author(s)
  小幡英章
- Total Pages
  11
- Publisher
  克誠堂出版麻酔増刊
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591613
[Book] 脊髄後角のα2受容体-その機能と下行性抑制系-、麻酔増刊VOL.562007
- Author(s)
  小幡英章
- Total Pages
  11
- Publisher
  克誠堂出版麻酔増刊
- Data Source
  KAKENHI-PROJECT-17591613
[Journal Article] ADHDが慢性疼痛を引き起こす中枢性感作のメカニズム2024
- Author(s)
  笠原諭、須藤貴史、高橋美和子、森田泰斗、小幡英章、丹羽真一
- Journal Title
  
  臨床麻酔
  
  Volume: 48 Pages: 51-61
- Data Source
  KAKENHI-PROJECT-22K09079
[Journal Article] ADHDが慢性疼痛を引き起こす中枢性感作のメカニズム　ー基礎と臨床の知見からー2024
- Author(s)
  笠原諭, 須藤貴史, 高橋美和子, 森田泰斗, 小幡英章, 丹羽真一
- Journal Title
  
  臨床麻酔
  
  Volume: 48 Pages: 51-61
- Data Source
  KAKENHI-PROJECT-20K09214
[Journal Article] 「痛覚変調性疼痛の神経メカニズム」：下行性疼痛制御系の可塑性と意義2024
- Author(s)
  小幡英章
- Journal Title
  
  ペインクリニック
  
  Volume: 45 Pages: 255-261
- Data Source
  KAKENHI-PROJECT-22K09079
[Journal Article] Rat model of attention-deficit hyperactivity disorder exhibits delayed recovery from acute incisional pain due to impaired descending noradrenergic inhibition2023
- Author(s)
  Suto Takashi、Kato Daiki、Koibuchi Ikuya、Arai Yuki、Ohta Jo、Hiroki Tadanao、Obata Hideaki、Saito Shigeru
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 5526-5526
- DOI
  10.1038/s41598-023-32512-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09214, KAKENHI-PROJECT-20K17775, KAKENHI-PROJECT-22K09079
[Journal Article] The efficacy of duloxetine depends on spinal cholinergic plasticity in neuropathic pain model rats2022
- Author(s)
  Kato Daiki、Suto Takashi、Obata Hideaki、Saito Shigeru
- Journal Title
  
  IBRO Neuroscience Reports
  
  Volume: 12 Pages: 188-196
- DOI
  10.1016/j.ibneur.2022.02.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09214, KAKENHI-PROJECT-22K09079
[Journal Article] Effectiveness of ultrasound-guided fascia hydrorelease on the coracohumeral ligament in patients with global limitation of the shoulder range of motion: a pilot study2022
- Author(s)
  Kimura Hiroaki、Suda Masei、Kobayashi Tadashi、Suzuki Shigeki、Fukui Sho、Obata Hideaki
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 19782-19782
- DOI
  10.1038/s41598-022-23362-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09079
[Journal Article] Randomized active-controlled study of a single preoperative administration of duloxetine to treat postoperative pain and numbness after posterior lumbar interbody fusion surgery2022
- Author(s)
  Hiroki Tadanao、Fujita Nao、Suto Takashi、Suzuki Hideo、Tsukamoto Noboru、Ohta Jo、Saito Shigeru、Obata Hideaki
- Journal Title
  
  Medicine
  
  Volume: 101 Issue: 50 Pages: e32306-e32306
- DOI
  10.1097/md.0000000000032306
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09079, KAKENHI-PROJECT-21K16545
[Journal Article] Spinal γ-Aminobutyric Acid Interneuron Plasticity Is Involved in the Reduced Analgesic Effects of Morphine on Neuropathic Pain2022
- Author(s)
  Hiroki Tadanao、Suto Takashi、Ohta Jo、Saito Shigeru、Obata Hideaki
- Journal Title
  
  The Journal of Pain
  
  Volume: 23 Issue: 4 Pages: 547-557
- DOI
  10.1016/j.jpain.2021.10.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16437, KAKENHI-PROJECT-21K16545, KAKENHI-PROJECT-22K09079
[Journal Article] 痛みの下行性制御とプラセボ鎮痛2021
- Author(s)
  小幡英章、荻野祐一
- Journal Title
  
  ペインクリニック
  
  Volume: ー
- Data Source
  KAKENHI-PROJECT-17H04321
[Journal Article] 痛みの下行性制御とプラセボ鎮痛2021
- Author(s)
  小幡英章、荻野祐一
- Journal Title
  
  ペインクリニック
  
  Volume: ー
- Data Source
  KAKENHI-PROJECT-18K19588
[Journal Article] 神経障害性疼痛の機序と治療2020
- Author(s)
  小幡英章
- Journal Title
  
  ペインクリニック
  
  Volume: 41 Pages: 621-62
- Data Source
  KAKENHI-PROJECT-18K19588
[Journal Article] 疼痛の発症機序－Fasciaはどのように関与するか2020
- Author(s)
  小幡英章
- Journal Title
  
  臨床スポーツ医学 2020;37(2):170-175.
  
  Volume: 37 Pages: 170-175
- Data Source
  KAKENHI-PROJECT-17H04321
[Journal Article] 疼痛の発症機序－Fasciaはどのように関与するか2020
- Author(s)
  小幡英章
- Journal Title
  
  臨床スポーツ医学
  
  Volume: 37 Pages: 170-175
- Data Source
  KAKENHI-PROJECT-18K19588
[Journal Article] 慢性痛の薬物療法: α2δリガンド・デュロキセチン2020
- Author(s)
  小幡英章
- Journal Title
  
  Bone Joint Nerve
  
  Volume: 10 Pages: 595-599
- Data Source
  KAKENHI-PROJECT-18K19588
[Journal Article] Loss of endogenous analgesia leads to delayed recovery from incisional pain in a rat model of chronic neuropathic pain2020
- Author(s)
  Ohta J, Suto T, Kato D, Hiroki T, Obata H, Saito
- Journal Title
  
  Brain Res
  
  Volume: 1727 Pages: 146568-146568
- DOI
  10.1016/j.brainres.2019.146568
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19588, KAKENHI-PROJECT-18K16436, KAKENHI-PROJECT-16H02678, KAKENHI-PROJECT-18K16437, KAKENHI-PROJECT-17H04321
[Journal Article] 中枢神経系における抗うつ薬の鎮痛メカニズム2020
- Author(s)
  小幡英章
- Journal Title
  
  ペインクリニック
  
  Volume: 41 Pages: 1607-1614
- Data Source
  KAKENHI-PROJECT-18K19588
[Journal Article] 中枢神経系における抗うつ薬の鎮痛メカニズム2020
- Author(s)
  小幡英章
- Journal Title
  
  ペインクリニック
  
  Volume: 41 Pages: 1607-1614
- Data Source
  KAKENHI-PROJECT-17H04321
[Journal Article] 慢性疼痛の発生機序2020
- Author(s)
  小幡英章
- Journal Title
  
  Progress in Medicine
  
  Volume: 40 Pages: 799-803
- Data Source
  KAKENHI-PROJECT-17H04321
[Journal Article] 神経障害性疼痛の機序と治療2020
- Author(s)
  小幡英章
- Journal Title
  
  ペインクリニック
  
  Volume: 41 Pages: 621-627
- Data Source
  KAKENHI-PROJECT-17H04321
[Journal Article] 慢性痛の薬物療法2020
- Author(s)
  小幡英章
- Journal Title
  
  日本医師会雑誌
  
  Volume: 149 Pages: 51-54
- Data Source
  KAKENHI-PROJECT-18K19588
[Journal Article] 慢性疼痛の発生機序2020
- Author(s)
  小幡英章
- Journal Title
  
  Progress in Medicine
  
  Volume: 40 Pages: 799-803
- Data Source
  KAKENHI-PROJECT-18K19588
[Journal Article] 慢性痛の薬物療法2020
- Author(s)
  小幡英章
- Journal Title
  
  日本医師会雑誌
  
  Volume: 149 Pages: 51-54
- Data Source
  KAKENHI-PROJECT-17H04321
[Journal Article] 慢性痛の薬物療法: α2δリガンド・デュロキセチン2020
- Author(s)
  小幡英章
- Journal Title
  
  Bone Joint Nerve
  
  Volume: 10 Pages: 595-599
- Data Source
  KAKENHI-PROJECT-17H04321
[Journal Article] Tropomyosin receptor kinase B receptor activation in the locus coeruleus restores impairment of endogenous analgesia at a late stage following nerve injury in rats2019
- Author(s)
  Suto T, Kato D, Obata H, Saito S
- Journal Title
  
  J Pain
  
  Volume: 20 Issue: 5 Pages: 600-609
- DOI
  10.1016/j.jpain.2018.11.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19588, KAKENHI-PROJECT-16H02678, KAKENHI-PROJECT-17H04321, KAKENHI-PROJECT-16K15673
[Journal Article] Strategies to treat chronic pain and strengthen impaired descending noradrenergic inhibitory system2019
- Author(s)
  Hayashida K, Obata H
- Journal Title
  
  Int J Mol Sci
  
  Volume: 20 Issue: 4 Pages: 822-822
- DOI
  10.3390/ijms20040822
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19588, KAKENHI-PROJECT-17H04321
[Journal Article] Spinal activation of tropomyosin receptor kinase-B recovers the impaired endogenous analgesia in neuropathic pain rats2018
- Author(s)
  Kato D, Suto T, Obata H, Saito S
- Journal Title
  
  Anesth Analg
  
  Volume: 印刷中 Issue: 2 Pages: 578-586
- DOI
  10.1213/ane.0000000000003592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19588, KAKENHI-PROJECT-16H02678, KAKENHI-PROJECT-17H04321, KAKENHI-PROJECT-16K15673
[Journal Article] 運動器慢性疼痛における末梢（性）感作と中枢（性）感作2018
- Author(s)
  徳岡宏文, 新庄勝浩, 小幡英章
- Journal Title
  
  新薬と臨床
  
  Volume: 69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19588
[Journal Article] Repeated administration of duloxetine suppresses neuropathic pain by accumulating effects of noradrenaline in the spinal cord.2018
- Author(s)
  Ito S, Suto T, Saito S, Obata H
- Journal Title
  
  Anesth Analg
  
  Volume: 126 Issue: 1 Pages: 298-307
- DOI
  10.1213/ane.0000000000002380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04321
[Journal Article] 運動器慢性疼痛における末梢（性）感作と中枢（性）感作2018
- Author(s)
  徳岡宏文, 新庄勝浩, 小幡英章
- Journal Title
  
  新薬と臨床
  
  Volume: 69 Pages: 1030-1042
- Data Source
  KAKENHI-PROJECT-17H04321
[Journal Article] 慢性痛時の青斑核：痛みの抑制と認知機能2017
- Author(s)
  林田健一郎、小幡英章
- Journal Title
  
  臨床麻酔
  
  Volume: 41 Pages: 1365-1370
- Data Source
  KAKENHI-PROJECT-17H04321
[Journal Article] Repeated administration of amitriptyline in neuropathic pain: Modulation of the noradrenergic descending inhibitory system2017
- Author(s)
  Hiroki T, Suto T, Saito S, Obata H
- Journal Title
  
  Anesth Analg
  
  Volume: 125 Issue: 4 Pages: 1281-1288
- DOI
  10.1213/ane.0000000000002352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04321
[Journal Article] Analgesic mechanisms of antidepressants for neuropathic pain2017
- Author(s)
  Obata H
- Journal Title
  
  Int J Mol Sci
  
  Volume: 18 Issue: 11 Pages: 2483-2483
- DOI
  10.3390/ijms18112483
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04321
[Journal Article] Spinal dopaminergic involvement in the antihyperalgesic effect of antidepressants in a rat model of neuropathic pain2017
- Author(s)
  Chen M, Hoshino H, Saito S, Yang Y, Obata H
- Journal Title
  
  Neurosci Lett
  
  Volume: 649 Pages: 116-123
- DOI
  10.1016/j.neulet.2017.04.017
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670678, KAKENHI-PROJECT-17H04321
[Journal Article] Endogenous analgesic effect of pregabalin: A double-blind and randomized controlled trial2017
- Author(s)
  Sugimine S, Araki T, Yamamoto K, Saito S, Obata H
- Journal Title
  
  Eur Ｊ Pain
  
  Volume: Feb 7 Issue: 6 Pages: 997-1006
- DOI
  10.1002/ejp.1007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670678
[Journal Article] Amitriptyline, but not pregabalin, reverses the attenuation of noxious stimulus-induced analgesia after nerve injury in rats2016
- Author(s)
  Matsuoka A, Suto T, Saito S, Obata H
- Journal Title
  
  Anesth Analg
  
  Volume: 未定 Issue: 2 Pages: 504-510
- DOI
  10.1213/ane.0000000000001301
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670678
[Journal Article] Brain morphological alternation in chronic pain patients with neuropathic characteristics.2016
- Author(s)
  Sugimine S, Ogino Y, Kawamichi H, Obata H, Saito S.
- Journal Title
  
  Free PMC Article
  
  Volume: 12 Pages: 1-7
- DOI
  10.1177/1744806916652408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02678, KAKENHI-PROJECT-26670678, KAKENHI-PROJECT-16K10980, KAKENHI-PROJECT-16K15673
[Journal Article] A randomized placebo-controlled study of preoperative pregabalin for postoperative analgesia in patients with spinal surgery2016
- Author(s)
  Fujita N, Tobe M, Tsukamoto N, Saito S, Obata H
- Journal Title
  
  J Clin Anesth
  
  Volume: 31 Pages: 149-153
- DOI
  10.1016/j.jclinane.2016.01.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670678
[Journal Article] 神経障害性疼痛に対する抗うつ薬の作用機序は？2015
- Author(s)
  小幡英章
- Journal Title
  
  Lisa
  
  Volume: 22 Pages: 20-3
- Data Source
  KAKENHI-PROJECT-23390373
[Journal Article] In vivo and in vitro evaluation of novel μ-opioid receptor agonist compounds2015
- Author(s)
  Nikaido Y, Kurosawa A, Saikawa H, Kuroiwa S, Suzuki C, Kuwabara N, Hoshino H, Obata H, Saito S, Saito T, Osada H, Kobayashi I, Sezutsu H, Takeda S
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 767 Pages: 193-200
- DOI
  10.1016/j.ejphar.2015.10.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670678
[Journal Article] Anti-hyperalgesic effects of intrathecal bupropion, a dopamine and noradrenaline reuptake inhibitor, in a rat model of neuropathic pain2015
- Author(s)
  Hoshino H, Obata, H, Nakajima K, Mieda R, Saito S
- Journal Title
  
  Anesthesia and Analgesia
  
  Volume: 120 Issue: 2 Pages: 460-6
- DOI
  10.1213/ane.0000000000000540
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390373, KAKENHI-PROJECT-25670664, KAKENHI-PROJECT-26670678
[Journal Article] 神経障害性疼痛に対する抗うつ薬の作用機序は？2014
- Author(s)
  小幡英章
- Journal Title
  
  Lisa
  
  Volume: 22 Pages: 20-3
- Data Source
  KAKENHI-PROJECT-26670678
[Journal Article] Peripheral nerve injury reduces analgesic effects of systemic morphine via spinal 5-hydroxytryptamine 3 receptors.2014
- Author(s)
  Kimura M, Obata H, Saito S
- Journal Title
  
  Anesthesiology
  
  Volume: 121 Issue: 2 Pages: 362-71
- DOI
  10.1097/aln.0000000000000324
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390373, KAKENHI-PROJECT-25670664
[Journal Article] The antiallodynic effect of intrathecal tianeptine is exerted by increased serotonin and norepinephrine in the spinal dorsal horn.2014
- Author(s)
  Lee HG, Choi JI, Yoon MH, Obata H, Saito S, Kim WM
- Journal Title
  
  Neuroscience Letters
  
  Volume: 583 Pages: 103-7
- DOI
  10.1016/j.neulet.2014.09.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390373, KAKENHI-PROJECT-25670664
[Journal Article] Efficacy and duration of analgesia from a sustained-release lidocaine sheet in humans.2014
- Author(s)
  Suzuki T, Tobe M, Obata H, Tabata Y, Saito S
- Journal Title
  
  International J of Drug Delivery
  
  Volume: 6 Pages: 75-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390373
[Journal Article] 神経障害性疼痛の疫学2014
- Author(s)
  小幡英章
- Journal Title
  
  臨床麻酔
  
  Pages: 491-498
- Data Source
  KAKENHI-PROJECT-24659691
[Journal Article] 3日間の合宿形式による慢性疼痛リハビリテーションブログラムの効果2013
- Author(s)
  14.宮本梓, 大高洋平,　森田光生, 加藤啓祐, 中村雅史, 藤田尚, 鈴木英雄, 木村雅文, 小幡英章, 齋藤繁
- Journal Title
  
  総合リハビリテーション
  
  Volume: 41 Pages: 761-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390373
[Journal Article] Relief of hypersensitivity after nerve injury from systemic donepezil involves spinal cholinergic and γ-amino butyric acid (GABA) mechanisms2013
- Author(s)
  Kimura M
- Journal Title
  
  Anesthesiology
  
  Volume: 118 Issue: 1 Pages: 173-180
- DOI
  10.1097/aln.0b013e318277a81c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390373, KAKENHI-PROJECT-24659691
[Journal Article] 整形外科関連疾患での慢性の痛みIII.部位別の治療方針. 5)慢性痛、術後慢性痛2013
- Author(s)
  荻野祐一, 小幡英章
- Journal Title
  
  ペインクリニック
  
  Volume: 34
- Data Source
  KAKENHI-PROJECT-24659691
[Journal Article] 整形外科関連疾患での慢性の痛みIII. 部位別の治療方針. 5) 慢性痛、術後慢性痛2013
- Author(s)
  荻野祐一, 小幡英章
- Journal Title
  
  ペインクリニック
  
  Volume: 34
- Data Source
  KAKENHI-PROJECT-23390373
[Journal Article] 痛みのバイオロジー下行性制御 : 抑制と促進2012
- Author(s)
  小幡英章
- Journal Title
  
  Lisa
  
  Volume: 19 Pages: 484-488
- Data Source
  KAKENHI-PROJECT-24659691
[Journal Article] Ondansetron reverses anti-hypersensitivity from clonidine in rats following peripheral nerve injury2012
- Author(s)
  Hayashida K
- Journal Title
  
  Anesthesiology
  
  Volume: 117 Issue: 2 Pages: 389-398
- DOI
  10.1097/aln.0b013e318260d381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390373, KAKENHI-PROJECT-24659691
[Journal Article] 術後鎮痛の薬理学的研究2012
- Author(s)
  木村雅文, 小幡英章
- Journal Title
  
  臨床麻酔
  
  Volume: 36 Pages: 862-868
- Data Source
  KAKENHI-PROJECT-24659691
[Journal Article] Long-term effect of epidural injection with slow-release lidocaine particles in a rat model of postoperative pain2012
- Author(s)
  Suto T
- Journal Title
  
  Br J Anaesth
  
  Volume: 109 Issue: 6 Pages: 957-967
- DOI
  10.1093/bja/aes302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390373, KAKENHI-PROJECT-24659691, KAKENHI-PROJECT-24791580
[Journal Article] Dexmedetomidine decreases hyperalgesia in neuropathic pain by increasing acetylcholine in the spinal cord2012
- Author(s)
  Kimura M
- Journal Title
  
  Neurosci Lett
  
  Volume: 529 Issue: 1 Pages: 70-74
- DOI
  10.1016/j.neulet.2012.08.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390373, KAKENHI-PROJECT-23659315, KAKENHI-PROJECT-24659691
[Journal Article] Antihypersensitivity effects of tramadol hydrochloride in a rat model of postoperative pain2012
- Author(s)
  Kimura M
- Journal Title
  
  Aneath Analg
  
  Volume: 115 Issue: 2 Pages: 443-449
- DOI
  10.1213/ane.0b013e31825683c3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390373, KAKENHI-PROJECT-23659315, KAKENHI-PROJECT-24659691
[Journal Article] Nontoxic genetic engineering of mesenchymal stem cells using serum-compatible pullulan-spermine/DNA anioplexes.2011
- Author(s)
  Thakor D, Teng YD, Obata H, Nagane K, Saito S, Tabata Y
- Journal Title
  
  Tissue Eng Part C Methods. 17
  
  Pages: 131-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] トラマドール2011
- Author(s)
  木村雅文、小幡英章
- Journal Title
  
  臨床麻酔
  
  Volume: 35 Pages: 1669-1674
- Data Source
  KAKENHI-PROJECT-23390373
[Journal Article] トラマドール2011
- Author(s)
  木村雅文, 小幡英章
- Journal Title
  
  臨床麻酔
  
  Volume: 35 Pages: 1669-1674
- Data Source
  KAKENHI-PROJECT-24659691
[Journal Article] 「Translational researchとしての痛みモデル」-術後痛モデル-2011
- Author(s)
  小幡英章
- Journal Title
  
  ペインクリニック
  
  Volume: 32 Pages: 1651-1657
- Data Source
  KAKENHI-PROJECT-23390373
[Journal Article] Long-term effect of sciatic nerve block with slow-release lidocaine in a rat model of postoperative pain.2010
- Author(s)
  Tobe M, Obata H, Suto T, Yokoo H, Nakazato Y, Tabata Y, Saito S.
- Journal Title
  
  Anesthesiology. 112
  
  Pages: 1473-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] Activation of astrocytes in the spinal cord contributes to the development of bilateral allodynia after peripheral nerve injury in rats.2010
- Author(s)
  Obata H
- Journal Title
  
  Brain Res
  
  Volume: 1363 Pages: 72-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] Activation of astrocytes in the spinal cord contributes to the development of bilateral allodynia after peripheral nerve injury in rats.2010
- Author(s)
  Obata H, Sakurazawa S, Kimura M, Saito S.
- Journal Title
  
  Brain Res. 1363
  
  Pages: 72-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] 慢性痛の分子化学的機序と臨床薬理学2010
- Author(s)
  小幡英章
- Journal Title
  
  麻酔
  
  Volume: 59
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] 慢性痛の分子化学的機序と臨床薬理学2010
- Author(s)
  小幡英章,荻野祐一
- Journal Title
  
  麻酔 59
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat.2010
- Author(s)
  Peters CM, Hayashida K, Ewan EE, Nakajima K, Obata H, Xu Q, Yaksh TL, Eisenach JC.
- Journal Title
  
  Brain Res. 1352
  
  Pages: 83-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] Monoamine-dependent, opioid-independent antihypersensitivity effects of intrathecally administered milnacipran, a serotonin noradrenaline reuptake inhibitor, in a postoperative pain model in rats.2010
- Author(s)
  Obata H, Kimura M, Nakajima K, Tobe M, Nishikawa K, Saito S.
- Journal Title
  
  J Pharmacol Exp Ther. 334
  
  Pages: 1059-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] Monoamine-dependent, opioid-independent antihypersensitivity effects of intrathecally administered milnacipran, a serotonin noradrenaline reuptake inhibitor, in a postonerative pain model in rats.2010
- Author(s)
  Obata H
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 334 Pages: 1059-1065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] Technical communication : percutaneous radiofrequency mandibular nerve rhizotomy guided by high-speed real-time computed tomography fluoroscopy.2010
- Author(s)
  Koizuka S, Saito S, Tobe M, Sekimoto K, Obata H, Koyama Y.
- Journal Title
  
  Anesth Analg. 111
  
  Pages: 763-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] CRPSの薬物療法:ガバペンチンと抗うつ薬2009
- Author(s)
  小幡英章
- Journal Title
  
  ペインクリニック 30
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] 先取り鎮痛法2009
- Author(s)
  小幡英章
- Journal Title
  
  整形・災害外科 52
  
  Pages: 563-569
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] α2受容体をターゲットにした慢性疼痛の治療2009
- Author(s)
  小幡英章
- Journal Title
  
  ペインクリニック 30
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] Percutaneous radio-frequency thermocoagulation of the Gasserian ganglion guided by high-speed real-time CT fluoroscopy.2009
- Author(s)
  Koizuka S, Saito S, Sekimoto K, Tobe M, Obata H, Koyama Y.
- Journal Title
  
  Neuroradiology 51
  
  Pages: 563-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] CRPSの薬物療法:ガバペンチンと抗うつ薬2009
- Author(s)
  小幡英章,林田健一郎
- Journal Title
  
  ペインクリニック 30
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] α2受容体をターゲットにした慢性疼痛の治療2009
- Author(s)
  小幡英章,林田健一郎,中島邦枝,齋藤繁
- Journal Title
  
  ペインクリニック 30
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] 末梢の急性炎症に対する5-HTの作用機序2009
- Author(s)
  小幡英章
- Journal Title
  
  生体の科学 60
  
  Pages: 346-347
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] Spinal microglial expression and mechanical hypersensitivity in a postoperative pain model : comparison with a neuropathic pain model.2009
- Author(s)
  Ito N, Obata H, Saito S.
- Journal Title
  
  Anesthesiology. 111
  
  Pages: 640-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] The nociceptive mechanism of 5-hydroxytryptamine released into the peripheral tissue in acute paininflammatory in rats.2009
- Author(s)
  Nakajima K, Obata H, Ito N, Goto F, Saito S.
- Journal Title
  
  Eur J Pain. 13
  
  Pages: 441-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] 疼痛治療に用いる薬物-Updata-:抗うつ薬(TCA, SNRI, SSRI)2008
- Author(s)
  小幡英章
- Journal Title
  
  ペインクリニック 29
  
  Pages: 625-632
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] Gabapentin acts within the locus coeruleus to alleviate neuropathic pain.2008
- Author(s)
  Hayashida K, Obata H, Nakajima K, Eisenach JC.
- Journal Title
  
  Anesthesiology. 109
  
  Pages: 1077-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] Management of chronic pain focused on alpha2 receptors2008
- Author(s)
  Hideaki Obata
- Journal Title
  
  Shinko
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591613
[Journal Article] A novel bFGF-GH injection therapy for two patients with severe ischemic limb pain2008
- Author(s)
  Ito N, Saito S, Yamada MH, Koizuka S, Obata H, et al.
- Journal Title
  
  Journal of Anesthesia 22
  
  Pages: 449-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] 慢性疼痛におけるセロトニンの役割2008
- Author(s)
  小幡英章
- Journal Title
  
  麻酔 57
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] Gabapentin acts within the locus coeruleus to alleviate neuropathic pain2008
- Author(s)
  Hayashida K, Obata H, et al.
- Journal Title
  
  Anesthesiology 109
  
  Pages: 1077-1084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] α2受容体をターゲットにした慢性疼痛の治療2008
- Author(s)
  小幡英章,林田健一郎,中島邦枝,齋藤繁
- Journal Title
  
  ペインクリニック 29
  
  Pages: 239-249
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] CRPSの薬物療法:ガバペンチンと抗うつ薬2008
- Author(s)
  小幡英章,林田健一郎
- Journal Title
  
  ペインクリニック 29
  
  Pages: 1189-1197
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] Alpha2-receptors in the dorsal horn of the spinal cord2007
- Author(s)
  Hideaki Obata
- Journal Title
  
  Kasseido
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591613
[Journal Article] Possible involvement of spinal noradrenergic mechanisms in the anti-allodynic effect of intrathecally administered 5-HT_<2C> receptor agonists in the rats with peripheral nerve injury2007
- Author(s)
  Hideaki Obata
- Journal Title
  
  Eur J Pharmacol 567
  
  Pages: 89-94
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591613
[Journal Article] Possiblξinvolvement of spinal noradrenergic mechanisms in the anti-allodyllic effbct of intrathecally administered 5-HT_2c receptor agonistsin the rats with peripheral nerve injury2007
- Author(s)
  Hideaki Obata
- Journal Title
  
  Eur J pharmacol 567
  
  Pages: 89-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591613
[Journal Article] Possible involvement of spinal noradrenergic mechanisms in the anti-allodynic effect of intrathecally administered 5-HT_2c receptor agonists in the rats with peripheral nerve injury2007
- Author(s)
  Hideaki Obata
- Journal Title
  
  Eur J Pharmacol 567
  
  Pages: 89-94
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591613
[Journal Article] Technique of pain management for pain clinicians, Toyo Miyazaki editor2007
- Author(s)
  Hideaki Obata
- Journal Title
  
  Nakayama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591613
[Journal Article] Spinal glial activation contribute to post-operative mechanical hypersensitivity in the rat2006
- Author(s)
  Hideaki Obata
- Journal Title
  
  Journal of pain 7
  
  Pages: 816-922
- Data Source
  KAKENHI-PROJECT-17591613
[Journal Article] Spinal glial activation contribute to post-operative mechanical hypersensitivity in the rat2006
- Author(s)
  Hideaki Obata
- Journal Title
  
  J pain 7
  
  Pages: 816-922
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591613
[Journal Article] Spinal glial activation contribute to post-operative mechanical hyperse nsitivity in the rat2006
- Author(s)
  Hideaki Obata
- Journal Title
  
  Journal of pain 7
  
  Pages: 816-922
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591613
[Journal Article] Monoamine-mediated anti-allodynic effects of intrathecally administered milnacipran, a serotonin noradrenaline reuptake inhibitor, in a rat model of neuropathic pain.2005
- Author(s)
  Hideaki Obata, Shigeru Saito, Shiro Koizuka, Koichi Nishikawa, Fumio Goto.
- Journal Title
  
  Anesth Analg 100
  
  Pages: 1406-1410
- Data Source
  KAKENHI-PROJECT-17591613
[Journal Article] 下行性抑制系と慢性疼痛2005
- Author(s)
  小幡英章
- Journal Title
  
  麻酔 54
- Data Source
  KAKENHI-PROJECT-17591613
[Journal Article] Systemic ketamine inhibits hypersensitivity after surgery via descending inhibitory pathways in rats.2005
- Author(s)
  Shiro Koizuka, Hideaki Obata, Masayuki Sasaki, Shigeru Saito, Fumio Goto.
- Journal Title
  
  Can J Anaesth 52
  
  Pages: 498-505
- Data Source
  KAKENHI-PROJECT-17591613
[Journal Article] Antihypersensitivity effects of tramadol hydrochloride in a rat model of postopera tive pain
- Author(s)
  Kimura M, Obata H, Saito S
- Journal Title
  
  Anesthesia and Analgesia
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390373
[Journal Article] An increase in spinal cord noradrenaline is a major contributor to the antihyperalgesic effect of antidepressants after peripheral nerve injury in the rat
- Author(s)
  Nakajima K, Obata H, Iriuchijima N, Saito S
- Journal Title
  
  Pain
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390373
[Journal Article] The nociceptive mechanism of 5-hydroxytryptamine released into the nerinheral tissue in acute inflammatory nain in rats
- Author(s)
  Nakajima K, Obata H, et al.
- Journal Title
  
  European Journal of Pain (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591823
[Journal Article] Peripheral nerve injury reduces analgesic effects of systemic morphine via spinal 5-hydroxytryptamine 3 receptors
- Author(s)
  Kimura M, Obata H, Saito S
- Journal Title
  
  Anesthesiology
  
  Volume: (掲載決定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659691
[Journal Article] Ondansetron reverses anti-hypersensitivity from clonidine in rats following peripheral nerve injury : Role of γ-amino butyric acid (GABA) in α2-adrenoceptor and 5-HT3 serotonin receptor analgesia
- Author(s)
  Hayashida K, Kimura M, Yoshizumi M, Hobo S, Obata H, Eisenach J C
- Journal Title
  
  Anesthesiology
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390373
[Presentation] 整形外科患者におけるADHDスクリーニング陽性率は40％と非常に高く、ADHD陽性者では不安やうつ、破局的思考が有意に強かった2023
- Author(s)
  中野裕子、笠原諭、大石理江子、小幡英章、大谷晃司、井上聡己
- Organizer
  日本麻酔科学会第70回学術集会
- Data Source
  KAKENHI-PROJECT-22K09079
[Presentation] 下行性抑制系の機能回復による神経障害性疼痛の治療2022
- Author(s)
  小幡英章
- Organizer
  第44回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-22K09079
[Presentation] Duloxetineの術前投与が腰椎後方椎体間固定術術後痛やしびれ症状へ及ぼす効果の検討2022
- Author(s)
  廣木忠直、藤田尚、鈴木英雄、塚本昇、須藤貴史、小幡英章
- Organizer
  日本麻酔科学会第69回学術集会
- Data Source
  KAKENHI-PROJECT-22K09079
[Presentation] 薬理遺伝学的アプローチによる青斑核ー内側前頭前野皮質の行動学的解析と慢性期神経障害性疼痛モデルにおける機能的変化2022
- Author(s)
  太田浄、廣木忠直、須藤貴史、小幡英章、齋藤繁
- Organizer
  第44回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-20K09214
[Presentation] Spinal nerve ligation（SNL）術後早期から慢性期にかけての誘発痛・自発痛の時間経過2022
- Author(s)
  須藤貴史、太田淨、小幡英章、齋藤繁
- Organizer
  第44回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-22K09079
[Presentation] 身体拘束ストレス下におけるラット髄核留置モデルでは、疼痛刺激後の側坐核におけるドパミン放出量は低下する2022
- Author(s)
  渡辺剛広、関口美穂、小幡英章、紺野愼一
- Organizer
  第44回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-22K09079
[Presentation] 薬理遺伝的アプローチによる青斑核-内側前頭前野皮質の行動学的解析と慢性期神経障害性疼痛モデルにおける機能的変化2022
- Author(s)
  太田淨、廣木忠直、須藤貴史、小幡英章、加藤房夫
- Organizer
  第44回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-22K09079
[Presentation] 痛みの慢性化と下行性疼痛調節系2021
- Author(s)
  小幡英章
- Organizer
  第26回緩和医療学会学術大会
- Data Source
  KAKENHI-PROJECT-18K19588
[Presentation] 痛みの慢性化と下行性疼痛調節系2021
- Author(s)
  小幡英章
- Organizer
  第26回緩和医療学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04321
[Presentation] 脊髄GABA作動性介在ニューロンの可塑的変化によりモルヒネの神経障害性疼痛への鎮痛効果が減弱する．2020
- Author(s)
  廣木忠直　須藤貴史　太田淨　齋藤繁　小幡英章
- Organizer
  日本麻酔科学会第67回学術集会
- Data Source
  KAKENHI-PROJECT-18K19588
[Presentation] Loss of endogenous analgesia leads to delayed recovery from incisional pain in a rat model of chronic neuropathic pain2019
- Author(s)
  Ohta J, Suto T, Hiroki T, Obata H
- Organizer
  Society for Neuroscience Annual Meeting 2019
- Data Source
  KAKENHI-PROJECT-17H04321
[Presentation] Loss of endogenous analgesia leads to delayed recovery from incisional pain in a rat model of chronic neuropathic pain2019
- Author(s)
  Ohta J, Suto T, Hiroki T, Obata H
- Organizer
  Society for Neuroscience Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19588
[Presentation] The plasticity of spinal γ-aminobutyric acid interneurons reduces analgesic effects of morphine in neuropathic pain2019
- Author(s)
  Hiroki T, Suto T, Ohta J, Saito S, Obata H
- Organizer
  Society for Neuroscience Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04321
[Presentation] The plasticity of spinal γ-aminobutyric acid interneurons reduces analgesic effects of morphine in neuropathic pain2019
- Author(s)
  Hiroki T, Suto T, Ohta J, Saito S, Obata H
- Organizer
  Society for Neuroscience Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19588
[Presentation] ファシアの急性痛・慢性痛への関与と慢性痛治療の問題点2019
- Author(s)
  小幡英章
- Organizer
  第124回日本解剖学会・全国学術集会シンポジウム
- Data Source
  KAKENHI-PROJECT-17H04321
[Presentation] ファシアの急性痛・慢性痛への関与と慢性痛治療の問題点2019
- Author(s)
  小幡英章
- Organizer
  第124回日本解剖学会・全国学術集会シンポジウム
- Data Source
  KAKENHI-PROJECT-18K19588
[Presentation] Attenuation of analgesic effect of duloxetine in a rat model of chronic neuropathic pain2018
- Author(s)
  Suto T, Kato D, Obata H, Saito S
- Organizer
  17th world congress on pain
- Data Source
  KAKENHI-PROJECT-17H04321
[Presentation] 神経障害性痛ではモルヒネの鎮痛作用が減弱する -セロトニン作動性下行性痛み調節系の可塑性変化についての検討-2018
- Author(s)
  廣木忠直、須藤貴史、齋藤繁、小幡英章
- Organizer
  日本麻酔科学会第65回学術集会
- Data Source
  KAKENHI-PROJECT-17H04321
[Presentation] ラット神経障害性疼痛モデルを用いたNaSSAおよびSNRIの鎮痛機序の検討2018
- Author(s)
  星野一、廣木忠直、齋藤繁、村川雅洋、小幡英章
- Organizer
  日本麻酔科学会第65回学術集会
- Data Source
  KAKENHI-PROJECT-17H04321
[Presentation] 神経障害性疼痛モデル慢性期におけるデュロキセチンによる鎮痛の減弱とそのメカニズム2018
- Author(s)
  須藤貴史、齋藤繁、小幡英章
- Organizer
  日本麻酔科学会第65回学術集会
- Data Source
  KAKENHI-PROJECT-18K19588
[Presentation] 直腸がん再発腫瘍摘出後の難治性疼痛に筋膜リリース注射が著効した一例2018
- Author(s)
  佐藤薫、中野裕子、大石理江子、小幡英章、村川雅洋
- Organizer
  日本ペインクリニック学会第52回大会
- Data Source
  KAKENHI-PROJECT-18K19588
[Presentation] Attenuation of analgesic effect of duloxetine in a rat model of chronic neuropathic pain2018
- Author(s)
  Suto T, Kato D, Obata H, Saito S
- Organizer
  17th world congress on pain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19588
[Presentation] 慢性痛の基礎研究 -具体的な方法と臨床への示唆-2018
- Author(s)
  小幡英章
- Organizer
  第42回東北ペインクリニック学会教育講演
- Invited
- Data Source
  KAKENHI-PROJECT-17H04321
[Presentation] 神経障害性疼痛モデル慢性期におけるデュロキセチンによる鎮痛の減弱とそのメカニズム2018
- Author(s)
  須藤貴史、齋藤繁、小幡英章
- Organizer
  日本麻酔科学会第65回学術集会
- Data Source
  KAKENHI-PROJECT-17H04321
[Presentation] 神経障害性痛ではモルヒネの鎮痛作用が減弱する -セロトニン作動性下行性痛み調節系の可塑性変化についての検討-2018
- Author(s)
  廣木忠直、須藤貴史、齋藤繁、小幡英章
- Organizer
  日本麻酔科学会第65回学術集会
- Data Source
  KAKENHI-PROJECT-18K19588
[Presentation] 痛みの伝達と抑制2017
- Author(s)
  小幡英章
- Organizer
  日本麻酔科学会第64回学術集会麻酔科領域講習
- Invited
- Data Source
  KAKENHI-PROJECT-17H04321
[Presentation] デュロキセチンは脊髄でのノルアドレナリンを介して慢性痛を抑制する2017
- Author(s)
  伊東今日子、須藤貴史、齋藤繁、小幡英章
- Organizer
  日本麻酔科学会第64回大会
- Data Source
  KAKENHI-PROJECT-17H04321
[Presentation] 神経障害モデルラットにおける抗うつ薬の痛覚過敏抑制効果における脊髄内ドーパミンの関与2017
- Author(s)
  星野一、小幡英章
- Organizer
  日本ペインクリニック学会第51回大会
- Data Source
  KAKENHI-PROJECT-17H04321
[Presentation] Tropomyosin receptor kinase b receptor antagonism reverses impairment of noradrenergic endogenous analgesia and enhances resolution from incisional pain in rat model.2017
- Author(s)
  Suto T, Kato D, Saito S, Obata H
- Organizer
  Society for Neuroscience Annual Meeting 2017
- Data Source
  KAKENHI-PROJECT-17H04321
[Presentation] Repeated administration of amitriptyline in neuropathic pain: modulation of the noradrenergic descending inhibitory system2017
- Author(s)
  Hiroki T, Saito S, Obata H
- Organizer
  Euroanesthesia 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04321
[Presentation] アミトリプチリンは神経障害により減弱したnoxious stimulus-induced analgesiaを回復させる2016
- Author(s)
  松岡宏晃、須藤貴史、齋藤繁、小幡英章
- Organizer
  日本麻酔科学会第63回大会
- Place of Presentation
  福岡市
- Year and Date
  2016-05-26
- Data Source
  KAKENHI-PROJECT-26670678
[Presentation] Effect of brain-deribed neurotropic factor signalings on the noradrenergic descending pain inhibitory systems2016
- Author(s)
  Suto T, Obata H, Saito S
- Organizer
  16th world congress on pain.
- Place of Presentation
  Ｙｏｋｏｈａｍａ
- Year and Date
  2016-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670678
[Presentation] 青斑核ノルアドレナリン作動性神経を介した内因性鎮痛の術後急性痛に対する影響と心拍変動を用いた他覚的検討2016
- Author(s)
  鯉淵郁也、須藤貴史、太田浄、小幡英章、齋藤繁
- Organizer
  日本麻酔科学会第63回大会
- Place of Presentation
  福岡市
- Year and Date
  2016-05-26
- Data Source
  KAKENHI-PROJECT-26670678
[Presentation] Amitriptyline, but not pregabalin, reverses the attenuation of noxious stimulus-induced analgesia after nerve injury in rats2016
- Author(s)
  Matsuoka H, Suto T, Tobe M, Saito S, Obata H
- Organizer
  IARS 2016 Annual Meeting
- Place of Presentation
  San Francisco
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670678
[Presentation] 内因性鎮痛系に対するプレガバリンの効果2016
- Author(s)
  杉峰里美、小幡英章、齋藤繁
- Organizer
  日本麻酔科学会第63回大会
- Place of Presentation
  福岡市
- Year and Date
  2016-05-26
- Data Source
  KAKENHI-PROJECT-26670678
[Presentation] 神経障害性疼痛モデルラットにおけるnoxious stimulus-induced analgesia2015
- Author(s)
  松岡宏晃、須藤貴史、小幡英章、斎藤繁
- Organizer
  第37回日本疼痛学会
- Place of Presentation
  熊本市
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-26670678
[Presentation] 神経障害性疼痛モデル慢性期における内因性疼痛抑制系の機能減弱とBrain Derived Neurotrophic Factorの役割2015
- Author(s)
  須藤貴史、小幡英章、斎藤繁
- Organizer
  第37回日本疼痛学会
- Place of Presentation
  熊本市
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-26670678
[Presentation] 神経障害性疼痛における下行性抑制系機能の変化とHiston Deacetylase inhiborの役割2014
- Author(s)
  橋谷舞、須藤貴史、林田健一郎、小幡英章、齋藤繁
- Organizer
  日本麻酔学会関東甲信越・東京支部第54回合同学術集会
- Place of Presentation
  東京都
- Year and Date
  2014-08-30
- Data Source
  KAKENHI-PROJECT-26670678
[Presentation] 神経障害性疼痛に対するモルヒネの鎮痛作用の減弱に脊髄の5-HT3受容体が関与している2014
- Author(s)
  木村雅文、小幡英章、斎藤繁
- Organizer
  日本麻酔科学会第61回大会
- Place of Presentation
  横浜市
- Year and Date
  2014-05-15
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] 神経障害性疼痛モデルラットにおける髄腔内ブプロピオンの鎮痛効果および脊髄後角でのノルアドレナリン・ドパミンの継時的推移2014
- Author(s)
  星野一、小幡英章、斎藤繁
- Organizer
  日本麻酔科学会第61回大会
- Place of Presentation
  横浜市
- Year and Date
  2014-05-16
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] 健常人の内因性鎮痛系の機能測定2014
- Author(s)
  杉峯里美、小幡英章、高澤知規、斎藤繁
- Organizer
  日本麻酔科学会第61回大会
- Place of Presentation
  横浜市
- Year and Date
  2014-05-16
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] 慢性疼痛患者の多面的評価と脳形態学的考察2014
- Author(s)
  杉峯里美、荻野祐一、川道拓東、小幡英章、斎藤繁
- Organizer
  日本麻酔科学会第61回大会
- Place of Presentation
  横浜市
- Year and Date
  2014-05-16
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] 神経障害痛ラットモデルにおける髄腔内ブプロピオンの鎮痛効果2013
- Author(s)
  星野一、小幡英章、齋藤繁
- Organizer
  日本ペインクリニック学会第47回大会
- Place of Presentation
  さいたま市
- Year and Date
  2013-07-14
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] プレオープニングシンポジウムザ討論I痛みの基礎どのくらい理解していますか?3)痛みの伝達と抑制-生理的な痛みと異常な痛み-2013
- Author(s)
  小幡英章
- Organizer
  日本ペインクリニック学会47回大会
- Place of Presentation
  さいたま市
- Year and Date
  2013-07-13
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] 神経障害性疼痛の治療における抗うつ薬のエビデンス2013
- Author(s)
  小幡英章
- Organizer
  日本ペインクリニック学会47回大会、ランチョンセミナー
- Place of Presentation
  さいたま市
- Year and Date
  2013-07-14
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] 慢性痛改善に有効な「慢性痛リハビリテーションプラン」2013
- Author(s)
  木村雅文、荻野祐一、中島邦枝、肥塚史郎、小幡英章、齋藤繁
- Organizer
  日本麻酔科学会第60回学術集会
- Place of Presentation
  札幌市
- Year and Date
  2013-05-24
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] 痛みの下行性制御2013
- Author(s)
  小幡英章
- Organizer
  第7回日本緩和医療薬学会年会ランチョンセミナー
- Place of Presentation
  さいたま市
- Year and Date
  2013-09-15
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] 神経可塑性から痛みの治療へ-神経損傷後の慢性痛の機序-2013
- Author(s)
  小幡英章
- Organizer
  日本麻酔科学会第60回学術集会
- Place of Presentation
  札幌市
- Year and Date
  2013-05-24
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] Peripheral nerve injury reduces antinociceptive effects of systemic morphine via spinal 5-HT3 receptors2013
- Author(s)
  Kimura M, Obata H, Saito S
- Organizer
  The European Anesthesiology Congress Euroanesthesia 2013
- Place of Presentation
  Barcerona
- Year and Date
  2013-06-02
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] Experience and perception of older persons with chronic pain: A qualitative research2012
- Author(s)
  Takai, Y., Yamamoto-Mitani, N., Obata, H., Kanda, K., Saito, S
- Organizer
  14th World Congress on Pain (International Association for the Study of Pain: IASP）
- Place of Presentation
  Milan Itary（Milano Convention Centre ）
- Data Source
  KAKENHI-PROJECT-23593428
[Presentation] Systemic donepezil reduces hypersensitivity after nerve injury by increasing acetylcholine concentration to induce-subsequent GABA release in the spinal cord2012
- Author(s)
  Obata H, Kimura M, Saito S
- Organizer
  14th world congress on pain
- Place of Presentation
  Milan
- Year and Date
  2012-08-31
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] Experience and perception of older persons with chronic pain : A qualitative research2012
- Author(s)
  Takai, Y., Yamamoto-Mitani, N., Obata, H., Kanda, K. & Saito, S.
- Organizer
  14th World Congress on Pain (International Association for the Study of Pain : IASP)
- Place of Presentation
  Milan Itary
- Data Source
  KAKENHI-PROJECT-23593428
[Presentation] 神経障害性疼痛時における抗うつ薬の鎮痛機序2012
- Author(s)
  中島邦枝、小幡英章、齋藤繁
- Organizer
  日本麻酔科学会第59回学術集会
- Place of Presentation
  神戸市
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] Experience and perception of older persons with chronic pain : a quantitative research2012
- Author(s)
  Takai Y, Yamamoto-Mitani N, Obata H, Kanda K, Saito S
- Organizer
  14th world congress on pain
- Place of Presentation
  Milan
- Year and Date
  2012-08-28
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] 「慢性痛リハビリテーションプラン」を開催して2012
- Author(s)
  木村雅文、戸部賢、荻野祐一、肥塚史郎、小幡英章、齋藤繁
- Organizer
  日本ペインクリニック学会第46回大会
- Place of Presentation
  松江市
- Year and Date
  2012-07-06
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] 神経障害性疼痛時のアセチルコリンを介した鎮痛作用2012
- Author(s)
  木村雅文、小幡英章、齋藤繁
- Organizer
  日本麻酔科学会第59回学術集会
- Place of Presentation
  神戸市
- Year and Date
  2012-06-08
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] Systemic donepezil reduces hypersensitivity after nerve injury by increasing acetylcholine concentration to induce-subsequent GABA release in the spinal cord2012
- Author(s)
  Obata H, Kimura M, Saito S
- Organizer
  14th world congress on pain
- Place of Presentation
  ミラノ
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] Systemic donepezil reduces hypersensitivity after nerve injury by increasing acetylcholine concentration to induce-subsequent GABA release in the spinal cord2012
- Author(s)
  Obata H
- Organizer
  14th world congress on pain
- Place of Presentation
  ミラノ
- Data Source
  KAKENHI-PROJECT-23390373
[Presentation] ドネペジルの鎮痛作用について-ラット神経障害性疼痛モデルとマイクロダイアライシスでの検討-2011
- Author(s)
  木村雅文、小幡英章
- Organizer
  第33回日本疼痛学会
- Place of Presentation
  松山市
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PROJECT-23390373
[Presentation] Antihypersensitivity effects of donepezil in a rat model of neuropathic pain2011
- Author(s)
  Kimura M, Obata H
- Organizer
  Society for Neuroscience Annual Meeting 2011
- Place of Presentation
  Washington DC
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-23390373
[Presentation] Spinal microglial expression and mechanical hypersensitivity in a postoperative pain model -comparison with a neuropathic pain model-.2010
- Author(s)
  Obata H, Ito N, Saito S.
- Organizer
  13th world congress on pain
- Place of Presentation
  Montreal Convention Centre, Montreal, Canada
- Year and Date
  2010-08-31
- Data Source
  KAKENHI-PROJECT-20591823
[Presentation] Antihypersensitivity effects of tramadol hydrochloride in a rat model of postoperative pain.2010
- Author(s)
  Kimura M, Obata H, Saito S.
- Organizer
  Society for Neuroscience Annual Meeting 2010
- Place of Presentation
  SanDiego Convention Center, San Diego, USA
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-20591823
[Presentation] Long-term effect of slow releasing lidocaine sheet and particle in a rat model of postoperative pain.2010
- Author(s)
  Suto T, Tobe H, Obata H, Saito S, Goto F.
- Organizer
  13th world congress on pain
- Place of Presentation
  Montreal Convention Centre, Montreal,Canada
- Year and Date
  2010-08-31
- Data Source
  KAKENHI-PROJECT-20591823
[Presentation] ガバペンチンは下行性ノルアドレナリン作動性神経を活性化して神経障害性疼痛を抑制する2009
- Author(s)
  小幡英章、林田健一郎、中島邦枝、齋藤繁、Eisenach JC
- Organizer
  日本麻酔科学会第56回学術集会
- Place of Presentation
  ポートピアホテル、神戸市
- Year and Date
  2009-08-16
- Data Source
  KAKENHI-PROJECT-20591823
[Presentation] Spinal microglial expression and mechanical hypersensitivity in a postoperative pain model.2009
- Author(s)
  小幡英章
- Organizer
  Society for Neuroscience Annual Meeting 2009
- Place of Presentation
  Chicago, U.S.A.
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-20591823
[Presentation] Spinal microglial expression and mechanical hypersensitivity in a postoperative pain model.2009
- Author(s)
  Obata H, Ito N, Saito S.
- Organizer
  Society for Neuroscience Annual Meeting 2009
- Place of Presentation
  Tinley Park-Convention Center, Chicago, USA
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-20591823
[Presentation] 抗うつ薬(SNRI/SSRI)の鎮痛作用、鎮痛補助薬-使用におけるエビデンスの確立に向けて2009
- Author(s)
  小幡英章
- Organizer
  第3回日本緩和医療薬学会年会
- Place of Presentation
  横浜市
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-20591823
[Presentation] Serotonin noradrenaline reuptake inhibitor(SNRI)の鎮痛メカニズム2008
- Author(s)
  中島邦枝、小幡英章、斎藤繁
- Organizer
  日本ペインクリニック学会第42回大会
- Place of Presentation
  福岡国際会議場、福岡市
- Year and Date
  2008-07-20
- Data Source
  KAKENHI-PROJECT-20591823
[Presentation] SNRI(ミルナシプラン)の鎮痛作用-ラット術後痛モデルでの検討-2008
- Author(s)
  小幡英章、中島邦枝、伊藤奈穂美、斎藤繁
- Organizer
  日本麻酔科学会第55回学術集会
- Place of Presentation
  パシフィコ横浜、横浜市
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20591823
[Presentation] Antinociceptive mechanism of serotonin noradrenaline reuptake inhibitor (SNRI) in a rat model of neuropathic pain.2008
- Author(s)
  Nakajima K, Obata H, Ito N, Saito S.
- Organizer
  Society for Neuroscience Annual Meeting 2008
- Place of Presentation
  Washington DC Convention Center, Washington DC, USA
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-20591823
[Presentation] Serotonin and noradrenaline reuptake inhibition by milnacipran reduces mechanical hypersensitivity after paw incision in rats.2008
- Author(s)
  Obata H, Nakajima K, Saito S, Goto F.
- Organizer
  12th world congress on pain
- Place of Presentation
  Convention Center, Glasgow, UK
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-20591823
[Presentation] Antinociceptive effects of SNRI mainly depends on noradrenergic mechanisms in a rat model of neuronathic pain2008
- Author(s)
  Nakajima K, Obata H, Saito S.
- Organizer
  Society for Neuroscience Annual Meeting 2008
- Place of Presentation
  Washington DC
- Year and Date
  2008-11-15
- Data Source
  KAKENHI-PROJECT-20591823
[Presentation] マイクロダイアリシス法を用いた脊髄後角におけるNA・5-HT の同時測定2008
- Author(s)
  中島邦枝、小幡英章、斎藤繁
- Organizer
  日本麻酔科学会第55回学術集会
- Place of Presentation
  パシフィコ横浜、横浜市
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-20591823
[Presentation] ラット神経因在疼痛モデルに対するグリア細胞抑制薬の効果2007
- Author(s)
  小幡英章
- Organizer
  日本疼痛学会
- Place of Presentation
  横浜
- Year and Date
  2007-07-07
- Data Source
  KAKENHI-PROJECT-17591613
[Presentation] Activation of astrocytes in the spinal cord contributes to bilateral development of allodynia after peripheral nerve injury in rats2007
- Author(s)
  Hideaki Obata
- Organizer
  Society for Neuroscience Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2007-11-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591613
[Presentation] Activation of astrbcytes in the spinal cord contributes to bilateral development of allodynia after pefipheral nerve injury in rats2007
- Author(s)
  Hideaki Obata
- Organizer
  Society for Neuroscience Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-17591613
[Presentation] ラット神経因性疼痛モデルに対するグリア細胞抑制薬の効果2007
- Author(s)
  小幡英章
- Organizer
  第29回日本疼痛学会
- Place of Presentation
  横浜
- Year and Date
  2007-07-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591613
[Presentation] Spinal glial activation contributes to the hypersensitivity after paw incision in rats2007
- Author(s)
  Hideaki Obata
- Organizer
  The 54th annual meeting of Japanese society of anesthesiologists
- Place of Presentation
  Sapporo
- Year and Date
  2007-06-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591613
[Presentation] Antiallonic effect of glial cell inhibitor in rats with neuropathic pain2007
- Author(s)
  Hideaki Obata
- Organizer
  The 29th annual meeting of the Japanese association for the study of pain
- Place of Presentation
  Yokohama
- Year and Date
  2007-07-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591613
[Presentation] 脊髄グリアの活性化はラット術後痛モデルの感覚過敏に関与している2007
- Author(s)
  小幡英章
- Organizer
  日本麻酔科学会第54回学術集会
- Place of Presentation
  札幌
- Year and Date
  2007-06-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591613
[Presentation] Peripheral nerve injury reduces antinociceptive　effects　of　systemic morphine via spinal 5-HT3 receptors
- Author(s)
  Kimura M, Obata H, Saito S
- Organizer
  The European Anesthesiology Congress Euroanesthesia 2013
- Place of Presentation
  Barcerona
- Year and Date
  2013-06-01 – 2013-06-04
- Data Source
  KAKENHI-PROJECT-23390373
[Presentation] 痛みの下行性制御
- Author(s)
  小幡英章
- Organizer
  第7回日本緩和医療薬学会年会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] 神経障害痛ラットモデルにおける髄腔内ブプロピオンの鎮痛効果
- Author(s)
  星野一、小幡英章、齋藤繁
- Organizer
  日本ペインクリニック学会第47回大会
- Place of Presentation
  大宮市
- Year and Date
  2013-07-13 – 2013-07-15
- Data Source
  KAKENHI-PROJECT-23390373
[Presentation] 神経障害性疼痛に対するモルヒネの鎮痛作用減弱に脊髄の5-HT3受容体が関与している
- Author(s)
  小幡英章、木村雅文、齋藤繁
- Organizer
  第36回日本疼痛学会
- Place of Presentation
  大阪市
- Year and Date
  2014-06-20 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-23390373
[Presentation] Peripheral nerve injury reduces antinociceptive　effects　of　systemic morphine via spinal 5-HT3 receptors
- Author(s)
  Kimura M, Obata H, Saito S
- Organizer
  Society for Neuroscience Annual Meeting 2014
- Place of Presentation
  Washington DC
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-23390373
[Presentation] 神経障害性疼痛の治療における抗うつ薬のエビデンス
- Author(s)
  小幡英章
- Organizer
  日本ペインクリニック学会47回大会
- Place of Presentation
  大宮市
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] Anti-hyperalgesic effects of intrathecal bupropion, a dopamine and noradrenaline reuptake inhibitor, in a rat model of neuropathic pain
- Author(s)
  Hoshino H, Obata, H, Nakajima K, Mieda R, Saito S
- Organizer
  Society for Neuroscience Annual Meeting 2014
- Place of Presentation
  Washington DC
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-23390373
[Presentation] 神経障害性疼痛に対するモルヒネの鎮痛作用の減弱に脊髄の5-HT3受容体が関与している
- Author(s)
  木村雅文、小幡英章、斎藤繁
- Organizer
  日本麻酔科学会第61回大会
- Place of Presentation
  横浜市
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-23390373
[Presentation] 痛みの伝達と抑制 -生理的な痛みと異常な痛み-
- Author(s)
  小幡英章
- Organizer
  日本ペインクリニック学会47回大会
- Place of Presentation
  大宮市
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] 神経可塑性から痛みの治療へ -神経損傷後の慢性痛の機序-
- Author(s)
  小幡英章
- Organizer
  日本麻酔科学会第60回学術集会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-24659691
[Presentation] 慢性疼痛における下行性抑制系の減弱-青斑核のグルタミン酸調節と脊髄ノルアドレナリン
- Author(s)
  須藤貴史、林田健一郎、小幡英章、齋藤繁
- Organizer
  第36回日本疼痛学会
- Place of Presentation
  大阪市
- Year and Date
  2014-06-20 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-26670678
[Presentation] 健常人の内因性鎮痛系の機能測定
- Author(s)
  杉峯里美、小幡英章、高澤知規、斎藤繁
- Organizer
  日本麻酔科学会第61回大会
- Place of Presentation
  横浜市
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-26670678

1. Suto Takashi (60739621)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
2. 林田健一郎 (40769634)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. SAITO Shigeru (40251110)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 後藤文夫 (00092015)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 紺野愼一 (70254018)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 加藤孝一 (50382198)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. KANDA Kiyoko (40134291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. FUTAWATARI Tamae (00143206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKEI Akemi (70431715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HORIKOSHI Masataka (80451722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TUTUMI Souiti (30323356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SEYAMA Ruka (10412991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAKAI Yukari (00404921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. YAMAMOTO Noriko (90280924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. ABE Yoshiki (30630785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SUZUKI Mizue (40283361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MIEDA Rie (10400772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 宿里充穗 (20525571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 織内昇 (40292586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 山中章弘 (60323292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 関口美穂 (00381400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 松本嘉寛 (10346794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 亀田拓哉 (50864005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 金内洋一 (70839448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 川辺浩志 (00582454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. KONNO Shin-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 廣木忠直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 荻野祐一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OBATA HIDEAKI 小幡 英章

OBATA Hidaaki 小幡 英章

OBATA Hideaki 小幡 英章

Research Projects

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内因性鎮痛の減弱は慢性痛の原因となり得るか？ーADHDでの検討ーPrincipal Investigator

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中脳辺縁ドパミン神経系の鎮痛機序とその可塑性に関する研究Principal Investigator

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A study to visualize chronic pain by cerebrospinal microglial imaging by the PETPrincipal Investigator

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Effect of socio-psychological stress on endogenous analgesiaPrincipal Investigator

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The role of the descending inhibitory system in endogenous analgesiaPrincipal Investigator

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Pharmacological mechanisms of locus coeruleus activation -recruitment of descending inhibition for treatment of neuropathic pain-Principal Investigator

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Mechanisms of effective drugs for management of neuropathic pain relationship between activation of descending inhibitory systems and pharmacologic plasticityPrincipal Investigator

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Pharmacologic plasticity of analgesic drugs in neuropathic pain states-measurement with monoamines in the spinal cord-Principal Investigator

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OBATA HIDEAKI 小幡英章

OBATA Hidaaki 小幡英章

OBATA Hideaki 小幡英章