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IWAMA Toru  岩間 亨

ORCIDConnect your ORCID iD *help
Researcher Number 20303498
Other IDs
Affiliation (based on the past Project Information) *help 2016 – 2023: 岐阜大学, 大学院医学系研究科, 教授
2012 – 2015: 岐阜大学, 医学(系)研究科(研究院), 教授
2012: 岐阜大学, 大学院・医学系研究科, 教授
2010 – 2011: 岐阜大学, 医学系研究科, 教授
2007 – 2009: Gifu University, 大学院・医学系研究科, 教授 … More
2006: GIFU UNIVERSITY, GRADUATE SCHOOL OF MEDICINE, PROFESSOR, 大学院医学系研究科, 教授
2005: 岐阜大学, 大学院・医学系研究科, 教授
2004: 岐阜大学, 大学院・医学研究科, 教授
2003: Gifu University, Neurosurgery, Professor, 医学部附属病院, 教授
2002 – 2003: 岐阜大学, 医学部附属病院, 講師
2000: GIFU UNIVERSITY, NEUROSURGERY, ASSISTANT PROFESSOR, 医学部・附属病院, 講師
1999: 岐阜大学, 医学部・附属病院, 助手
1998 – 1999: 岐阜大学, 医学部附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Cerebral neurosurgery / Cerebral neurosurgery / Basic Section 56010:Neurosurgery-related
Except Principal Investigator
Cerebral neurosurgery / Basic Section 56010:Neurosurgery-related / Cerebral neurosurgery / Neurosurgery
Keywords
Principal Investigator
p53 / apoptosis / Bcl-2 family / グリオーマ / アポトーシス / セラミド / 白質神経傷害 / クモ膜下出血 / マウスSAHモデル / 白質傷害 … More / クモ膜下出血(SAH) / radiation / glima / caspase-3 / ヒト悪性膠腫 / 放射線 / sphingomyelinase / glioma / ceramide / caspase / anti-cancer drugs / 組織学的分化度(悪性度) / 抗癌剤感受性 / 活性酸素 / スフィンゴミエリナーゼ / カスパーゼ / 抗癌剤 / Bcl-2family / 主幹動脈狭窄症炎症 / 動脈硬化進展作用 / 炎症性サイトカイン / 主幹動脈狭窄症 / EGF受容体 / EGF / 脳腫瘍幹細胞 / 神経幹細胞 / PA6 / 分化 / HGF / ES細胞 … More
Except Principal Investigator
traumatic brain injury / neurogenesis / caspase / 悪性脳腫瘍 / 脂肪組織由来幹細胞 / 脳虚血 / 神経膠芽腫 / 抗腫瘍作用 / テモゾロミド耐性 / 小胞体ストレス / glioblastoma / 新規治療 / 脳転移 / 血管内皮グリコカリックス / 急性脳神経障害 / 神経保護療法 / 脂肪組織由来幹細胞分泌因子 / 脳卒中モデル / 神経傷害 / CYP2C19 / クロピドグレル / CYP2CI9 / クロピトグレル / 血小板凝集能 / 抗血小板剤不応症 / 血小板不応症 / 抗血小板薬 / neurotrophic factors / cerebral ischemia / neural stem cell / brain ischemia / 神経栄養因子 / 頭部外傷 / reactive oxygen species / sphingomyelinase / hypoxia / ceramide / Bcl-2 family / apoptosis / phospholipase D / ホスホリパーゼC / 低酸素刺激 / 虚血性脳血管障害 / Bcl-2 / スフィンゴミエリナーゼ / カスパーゼ / ホスホリパーゼD / ネクローシス / アポトーシス / セラミド / 活性酸素 / differentiation / malignancy / TRAP assay / brain tumor / telomerase activity / Telomerase / 乏突起膠腫 / cAMP / 培養細胞 / 増殖能 / 文化誘導 / テロメラーゼ / グリオーマ / 脳腫瘍 / テロメレース / 分化誘導 / テロメレース活性 / 悪性度 / TRAP法 / 脳腫瘍幹細胞 / COLA1 / IGFBP7 / IDH1変異 / 培養上清 / 培養 / 移植 / ヒト脂肪細胞 / 脳虚血モデル / 脂肪由来幹細胞 / 脂肪由来間葉系幹細胞 / 細胞移植治療 / 骨髄由来間葉系幹細胞 / 脂肪組織由来間葉系幹細胞 / 再狭窄 / 薬剤コーティング / 遺伝子 / ステント / 脳血管拡張術 / Neural stem cells / Hepatocyte geowth factor / Embryonic stem cell / Neuronal progenitor / Neuronal differentiation / Neural stem cell / Hepatocyte growth factor / WGAーHRP / 神経可塑性 / 神経幹細胞 / Nestin / ラット / 一次体性感覚野 / 一次運動野 / 視床 Less
  • Research Projects

    (19 results)
  • Research Products

    (61 results)
  • Co-Researchers

    (40 People)
  •  グリコカリックスに着目した新たな悪性脳腫瘍治療法の研究

    • Principal Investigator
      中山 則之
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Gifu University
  •  小胞体ストレスがテモゾロミドに及ぼす影響

    • Principal Investigator
      庄田 健二
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Gifu University
  •  Elucidation of white matter nerve injury after subarachnoid hemorrhage for the development of novel treatment methodsPrincipal Investigator

    • Principal Investigator
      Iwama Toru
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Gifu University
  •  Development of a novel neuroprotective therapy using adipose-derived stem cells secreted factor

    • Principal Investigator
      Egashira Yusuke
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Gifu University
  •  Treatment target of hyper residual platelet reactivity in patients receiving anti platelet therapy

    • Principal Investigator
      Enomoto Yukiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Gifu University
  •  The possible role of IDH1 mutation, IGFBP7 and COLA1 for gliomagenesis.

    • Principal Investigator
      SOEDA Akio
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurosurgery
    • Research Institution
      Gifu University
  •  Mechanism of atherosclerosis progression by platelet-derived inflammatory cytokines in carotid artery stenosisPrincipal Investigator

    • Principal Investigator
      IWAMA Toru
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Gifu University
  •  Establishment of the purification and culture methods of human adipose-derived stem cells as an autogenous graft to ischemic brain tissue

    • Principal Investigator
      YOSHIMURA Shinichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Gifu University
  •  脂肪由来間葉系細胞を用いた脳虚血に対する移植再生療法の確立

    • Principal Investigator
      吉村 紳一
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Gifu University
  •  EGF,EGFRが脳腫瘍幹細胞に及ぼす影響Principal Investigator

    • Principal Investigator
      岩間 亨
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Gifu University
  •  脳血管拡張術後の再狭窄に対する薬剤・遺伝子コーティングステントの開発

    • Principal Investigator
      吉村 紳一
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Gifu University
  •  Analysis of regulation mechanism of neurogenesis after traumatic brain injury and cerebral ischemia-roles of neurotrophic factors

    • Principal Investigator
      YOSHIMURA Shinichi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Gifu University
  •  肝細胞増殖因子(HGF)による神経幹細胞の増殖・分化誘導の制御Principal Investigator

    • Principal Investigator
      岩間 亨, 郭 泰彦
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Gifu University
  •  脳移植を目指した新しい神経幹細胞培養システムの開発Principal Investigator

    • Principal Investigator
      岩間 亨
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Gifu University
  •  p53-Independent ceramide formation in human glioma cells during gamma-radiation-induced apoptosis.Principal Investigator

    • Principal Investigator
      IWAMA Toru
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      GIFU UNIVERSITY
  •  実験的視床破壊後の神経回路代償機構に関する検討

    • Principal Investigator
      西村 康明
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Gifu University
  •  Analysis of signal transduction during ceramide-mediated apoptotic pathway in hypoxic PC12 cell death

    • Principal Investigator
      SAKAI Noboru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      GIFU UNIVERSITY
  •  SIGNIFICANCE OF BAX/BCL-2 EXPRESSION RATIO DURING APOPTOTIC PATHWAYS OF HUMAN GLIOMA CELLSPrincipal Investigator

    • Principal Investigator
      IWAMA Toru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      GIFU UNIVERSITY
  •  Telomerase activity in brain tumors.

    • Principal Investigator
      SAKAI Noboru
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      GIFU UNIVERSITY

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All Journal Article Presentation Book

  • [Book] 脳神経疾患 最新の治療 2024-20262024

    • Author(s)
      江頭裕介, 岩間 亨
    • Publisher
      株式会社南江堂
    • Data Source
      KAKENHI-PROJECT-20K09345
  • [Book] Medical Technology 35(7) 脳腫瘍幹細胞を標的としたテーラーメイド医療の実現を目指して2007

    • Author(s)
      副田明男, 岡 直樹, 岩間 亨
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-19659362
  • [Journal Article] Prevention of vincristine-induced peripheral neuropathy by protecting the endothelial glycocalyx shedding2024

    • Author(s)
      Ohmura Kazufumi、Kinoshita Takamasa、Tomita Hiroyuki、Okada Hideshi、Shimizu Masayoshi、Mori Kosuke、Taniguchi Toshiaki、Suzuki Akio、Iwama Toru、Hara Akira
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 691 Pages: 149286-149286

    • DOI

      10.1016/j.bbrc.2023.149286

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18311, KAKENHI-PROJECT-22K09203, KAKENHI-PROJECT-23K06276, KAKENHI-PROJECT-23K24430, KAKENHI-PROJECT-23K28016
  • [Journal Article] Nafamostat protects against early brain injury after subarachnoid hemorrhage in mice2022

    • Author(s)
      Matsubara Hirofumi、Imai Takahiko、Tsuji Shohei、Oka Natsumi、Egashira Yusuke、Enomoto Yukiko、Nakayama Noriyuki、Nakamura Shinsuke、Shimazawa Masamitsu、Iwama Toru、Hara Hideaki
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 148 Issue: 1 Pages: 65-72

    • DOI

      10.1016/j.jphs.2021.10.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K17926, KAKENHI-PROJECT-20K09345, KAKENHI-PROJECT-22KJ2580
  • [Journal Article] Involvement of Cerebral Blood Flow on Neurological and Behavioral Functions after Subarachnoid Hemorrhage in Mice2021

    • Author(s)
      Matsubara Hirofumi、Imai Takahiko、Tsuji Shohei、Oka Natsumi、Ohba Takuya、Yamada Tetsuya、Egashira Yusuke、Nakamura Shinsuke、Shimazawa Masamitsu、Iwama Toru、Hara Hideaki
    • Journal Title

      Journal of Stroke and Cerebrovascular Diseases

      Volume: 30 Issue: 9 Pages: 105952-105952

    • DOI

      10.1016/j.jstrokecerebrovasdis.2021.105952

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K17926, KAKENHI-PROJECT-20K09345
  • [Journal Article] Ristocetin induces phosphorylated-HSP27 (HSPB1) release from the platelets of type 2 DM patients: Anti-platelet agent-effect on the release.2018

    • Author(s)
      Tokuda H, Kuroyanagi G, Onuma T, Enomoto Y, Doi T, Iida H, Otsuka T, Ogura S, Iwama T, Kojima K, Kozawa O.
    • Journal Title

      Biomed Rep

      Volume: 4 Pages: 365-372

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10717
  • [Journal Article] Optimal platelet function test for in-stent tissue protrusion following carotid artery stenting.2018

    • Author(s)
      Tsujimoto M, Enomoto Y, Miyai M, Egashira Y, Iwama T.
    • Journal Title

      J Int Med Res

      Volume: 46 Pages: 1866-1875

    • Data Source
      KAKENHI-PROJECT-16K10717
  • [Journal Article] Rac Regulates the TRAP-Induced Release of Phosphorylated-HSP27 from Human Platelets via p38 MAP Kinase but Not JNK.2018

    • Author(s)
      Uematsu K, Enomoto Y, Onuma T, Tsujimoto M, Doi T, Matsushima-Nishiwaki R, Tokuda H, Ogura S, Iida H, Kozawa O, Iwama T.
    • Journal Title

      Cell Physiol Biochem

      Volume: 49 Issue: 4 Pages: 1523-1538

    • DOI

      10.1159/000493456

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10717
  • [Journal Article] Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor.2017

    • Author(s)
      Onuma T, Tanabe K, Kito Y, Tsujimoto M, Uematsu K, Enomoto Y, Matsushima-Nishiwaki R, Doi T, Nagase K, Akamatsu S, Tokuda H, Ogura S, Iwama T, Kozawa O, Iida H.
    • Journal Title

      Thromb Res.

      Volume: 156 Pages: 91-100

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10717
  • [Journal Article] The evidence of glioblastoma heterogeneity.2015

    • Author(s)
      Soeda A, Hara A, Kunisada T, Yoshimura S, Iwama T, Park DM
    • Journal Title

      Sci Rep

      Volume: 5 Issue: 1 Pages: 7979-7979

    • DOI

      10.1038/srep07979

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26670639
  • [Journal Article] Surface proteine dynamics in glioma stem cells.2014

    • Author(s)
      Soeda A, Ohe N, Lee D, Iwama T, Park DM
    • Journal Title

      Austin J Neurosurg

      Volume: 1 Pages: 7-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670639
  • [Journal Article] The growth factor progranulin attenuates neuronal injury induced by cerebral ischemia-reperfusion through the suppression of neutrophil recruitment.2013

    • Author(s)
      Egashira Y, Suzuki Y, Azuma Y, Takagi T, Mishiro K, Sugitani S, Tsuruma K, Shimazawa M, Yoshimura S, Kashimata M, Iwama T, Hara H
    • Journal Title

      J Neuroinflammation

      Volume: 10 Issue: 1 Pages: 105-105

    • DOI

      10.1186/1742-2094-10-105

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659646, KAKENHI-PROJECT-24791493
  • [Journal Article] Selection of carotid artery stenting or endarterectomy based on magnetic resonance plaque imaging reduced periprocedural adverse events2013

    • Author(s)
      Yoshimura S,Yamada K,Kawasaki M,Asano T,Kanematsu M,Miyai M,Enomoto Y,Egashira Y,Iwama T
    • Journal Title

      J Stroke Cerebrovasc Dis

      Volume: 22 Pages: 1082-1087

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659646
  • [Journal Article] Silent coronary artery disease in Japanese patients undergoing carotid artery stenting.2013

    • Author(s)
      Enomoto Y, Yoshimura S, Yamada K, Kawasaki M, Nishigaki K, Minatoguchi S, Iwama T
    • Journal Title

      J Stroke Cerebrovasc Dis

      Volume: 22 Pages: 1163-1168

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659646
  • [Journal Article] Silent coronary artery disease in Japanese patients undergoing carotid artery stenting2013

    • Author(s)
      Enomoto Y,Yoshimura S,Yamada K,Kawasaki M,Nishigaki K,Minatoguchi S,Iwama T
    • Journal Title

      J Stroke Cerebrovasc Dis

      Volume: 22 Pages: 1163-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659646
  • [Journal Article] Selection of carotid artery stenting or endarterectomy based on magnetic resonance plaque imaging reduced periprocedural adverse events.2013

    • Author(s)
      Yoshimura S, Yamada K, Kawasaki M, Asano T, Kanematsu M, Miyai M, Enomoto Y, Egashira Y, Iwama T
    • Journal Title

      J Stroke Cerebrovasc Dis

      Volume: 22 Pages: 1082-1087

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659646
  • [Journal Article] The conditioned medium of murine and human adipose-derived stem cells exerts neuroprotective effects against experimental stroke model2012

    • Author(s)
      Egashira Y, Sugitan S, Suzuk Y Mishiro K Tsuruma K Shimazaswa M, Yoshimura S, Iwama T, Hara H
    • Journal Title

      Brain Res

      Volume: 1461 Pages: 87-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Journal Article] Pharmacological inhibition of TLR4-NOX4 signal protects against neuronal death in transient focal ischemia2012

    • Author(s)
      Suzuki Y Hattori K, Hamanaka J, Murase T, Egashira Y, Mishiro K, Ishiguro M, Tsuruma K Hirose Y, Tanaka H, Yoshimura S, Shimazawa M, Inagaki N, Nagasawa H Iwama T, Hara H
    • Journal Title

      Sci Rep

      Volume: 2 Pages: 896-896

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Journal Article] Visualization of internal carotid artery atherosclerotic plaques in symptomatic and asymptomatic patients : a comparison of optical coherence tomography and intravascular ultrasound2012

    • Author(s)
      Yoshimura S,Kawasaki M,Yamada K,Enomoto Y,Egashira Y,Hattori A,Nishigaki K,Minatoguchi S,Iwama T
    • Journal Title

      AJNR Am J Neuroradiol

      Volume: 33 Issue: 2 Pages: 308-13

    • DOI

      10.3174/ajnr.a2740

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659646
  • [Journal Article] A Rho kinase (ROCK) inhibitor fasudil prevents matrix metalloproteinase-9-related hemorrhagic transformation in mice treated with tissue plasminogen activator.2012

    • Author(s)
      Ishiguro M, Kawasaki K, Suzuki Y, Ishizuka F, Mishiro K, Egashira Y, Ikegaki I, Tsuruma K, Shimazawa M, Yoshimura S, Iwama T, Hara H
    • Journal Title

      Neurosience

      Volume: 220 Pages: 302-312

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Journal Article] 2-Decenoic acid ethyl ester, a compound that elicits neurotrophin-like intracellular signals, facilitating functional recovery from cerebral nfarction in mice2012

    • Author(s)
      Tanaka Y, Fukumitsu H. Soumiya H Yoshimura S, Iwama T, Furukawa S
    • Journal Title

      Int J Mol Sci

      Volume: 13 Pages: 4968-4981

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Journal Article] Comparison of mesenchymal stem cells from adipose tissue and bone marrow for ischemic stroke therapy2011

    • Author(s)
      Ikegame Y, Yamashita K, Hayashi SI, Mizuno H, Tawada M, You F, Yamada K, Tanaka Y, Egashira Y, Nakashima S, Yoshimura S, Iwama T
    • Journal Title

      CYTOTHERAPY

      Volume: 13 Pages: 675-685

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Journal Article] Blockade of phosphodiesterase-III protects against oxygen-glucose deprivation in endothelial cells by upregulation of VE-cadherin2011

    • Author(s)
      Ishiguro M, Suzuki Y, Mishiro K, Kakino M, Tsuruma K, Shimazawa M, Yoshimura S Iwama T, Hara H
    • Journal Title

      Curr Neurovasc Res

      Volume: 8 Pages: 86-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Journal Article] cAMP regulates ADP-induced HSP27 phosphorylation in human platelets2011

    • Author(s)
      Enomoto Y, Adach S, Doi T, Natsume H Kato K, Matsushima-Nishiwaki R Akamatsu S, Tokuda H, Yoshimura S, Otsuka T, Kozawa O, Iwama T
    • Journal Title

      Int J Mol Med

      Volume: 27 Pages: 695-700

    • NAID

      120006341953

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Journal Article] Comparison of mesenchymal stem cells from adipose tissue and bone marrow for ischemic stroke therapy2011

    • Author(s)
      Ikegame Y, Yamashita K Hayashi SI, Mizuno H, Tawada M, You F, Yamada K, Tanaka Y, Egashira Y, Nakashima S, Yoshimura S, Iwama T
    • Journal Title

      CYTOTHERAPY

      Volume: 13 Pages: 675-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Journal Article] Comparison of mesenchymal stem cells from adipose tissue and bone marrow for ischemic stroke therapy2011

    • Author(s)
      Ikegame Y, Yamashita K, Hayashi SI, Mizuno H Tawada M, You F, Yamada K, Tanaka Y, Egashira Y, Nakashima S, Yoshimura SI, Iwama T
    • Journal Title

      Cytotherapy

      Volume: 13 Pages: 675-685

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Journal Article] Phosphodiesterase-III inhibitor prevents hemorrhagic transformation induced by focal cerebral ischemia in mice treated with tPA2010

    • Author(s)
      Ishiguro M, Mishiro K, Fujiwara Y, Chen H, Izuta H, Tsuruma K, Shimazawa M, Yoshimura S, Satoh M, Iwama T, Hara H
    • Journal Title

      PLoS One

      Volume: 5(12)

    • NAID

      120006341231

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Journal Article] Neutrophil elastase inhibitor prevents ischemic brain damage via reduction of vasogenic edema2010

    • Author(s)
      Ikegame Y, Yamashita K, Hayashi S, Yoshimura S, Nakashima S, Iwama T
    • Journal Title

      Hypertens Res

      Volume: 33 Pages: 703-7

    • NAID

      10026520284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Journal Article] Overexpression of immediate early gene X-1 (IEX-1) enhances gamma-radiation-induced apoptosis of human glioma cell line, U87-MG.2009

    • Author(s)
      Yamashita K, Nakashima S, You F, Hayashi S, Iwama T.
    • Journal Title

      Neuropathology 29(1)

      Pages: 20-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659361
  • [Journal Article] Combination effects of normobaric hyperoxia and edaravone on focal cerebral ischemia-induced neuronal damage in mice.2008

    • Author(s)
      Nonaka Y, Shimazawa M, Yoshimura S, Iwama T, Hara H.
    • Journal Title

      Neurosci Lett 441

      Pages: 224-228

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659362
  • [Journal Article] Present status of Moyamoya disease in Japan.2008

    • Author(s)
      Iwama T, Yoshimura S
    • Journal Title

      Acta Neurochir Suppl 103

      Pages: 115-118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659362
  • [Journal Article] Propofol exerts greater neuroprotection with disodium edetate than without it.2008

    • Author(s)
      Kotani Y, Nakajima Y, Hasegawa T, Satoh M, Nagase H, Shimazawa M, Yoshimura S, Iwama T, Hara H.
    • Journal Title

      J Cereb Blood Flow Metab 28

      Pages: 354-366

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659361
  • [Journal Article] Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells.2008

    • Author(s)
      Soeda A, Inagaki A, Oka N, Ikegame Y, Aoki H, Yoshimura S, Nakashima S, Kunisada T, Iwama T.
    • Journal Title

      J Biol Chem. 283

      Pages: 10958-10966

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659361
  • [Journal Article] Combination effects of normobaric hyperoxia and edaravone on focal cerebral ischemia-induced neuronal damage in mice.2008

    • Author(s)
      Nonaka Y, Shimazawa M, Yoshimura S, Iwama T, Hara H.
    • Journal Title

      Neurosci Lett 441

      Pages: 224-228

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659361
  • [Journal Article] Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells.2008

    • Author(s)
      Soeda A, Inagaki A, Oka N, Ikegame Y, Aoki H, Yoshimura S, Nakashima S, Kunisada T, Iwama T.
    • Journal Title

      J Biol Chem. 283

      Pages: 10958-10966

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659362
  • [Journal Article] Prevention of in vitro and in vivo acute ischemic neuronal damage by(2S)-1-(4-amino-2, 3, 5-trimethylphenoxy)-3-{4-[4-(4-fluorobenzy1)pheny1]-1-piperaziny1}-2-propanol dimethanesulfonate(SUN N8075), a novel neuro protective agent with antioxidant properties.2007

    • Author(s)
      Kotani Y, Morimoto N, Oida Y, Tamura Y, Tamura S, Inoue T, Shimazawa M, Yoshimura S, Iwama T, Hara H
    • Journal Title

      Neuroscience 149

      Pages: 779-788

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659361
  • [Journal Article] Fasudil, a Rho Kinase(ROCK)inhibitor, protects against ischemic neuronal damage in vitro and in vivo by acting directly on neurons.2007

    • Author(s)
      Yamashita K, Kotani Y, Nakajima Y, Shimazawa M, Yoshimura S, Nakashima S, Iwama T, Hara H
    • Journal Title

      Brain Res 1154

      Pages: 215-224

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659361
  • [Journal Article] VEGF promotes tumorigenesis and angiogenesis of human glioblastoma stem cells.2007

    • Author(s)
      Oka N, Soeda A, Inagaki A, Onodera M, Maruyama H, Hara A, Kunisada T, Mori H, Iwama T
    • Journal Title

      Biochem Biophys Res Commun 360

      Pages: 553-559

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659361
  • [Journal Article] VEGF promotes tumorigenesis and angiogenesis of human glioblastoma stem cells.2007

    • Author(s)
      Oka N, Soeda A, Inagaki A, Onodera M, Maruyama H, Hara A, Kunisada T, Mori H, Iwama T
    • Journal Title

      Biochem Biophys Res Commun 360

      Pages: 553-559

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659362
  • [Journal Article] Long-term maintenance of brain tumor stem cell properties under at non-adherent and adherent culture-conditions.2007

    • Author(s)
      Inagaki A, Soeda A, Oka N, Kitajima H, Nakagawa J, Motohashi T, Kunisada T, Iwama T
    • Journal Title

      Biochem Biophys Res Commun 361

      Pages: 586-592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659362
  • [Journal Article] 脳損傷後のNeurogenesis制御機構の解析-再生医療ヘの展望-2006

    • Author(s)
      吉村紳一, 岩間 亨
    • Journal Title

      脳循環代謝 第18巻

      Pages: 176-179

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390406
  • [Journal Article] 脳損傷後のNeurogenesis制御機構の解析-再生医療への展望-2006

    • Author(s)
      吉村紳一, 岩間 亨
    • Journal Title

      脳循環代謝 18・4

      Pages: 176-179

    • Data Source
      KAKENHI-PROJECT-16390406
  • [Journal Article] Culture method for the induction of neurospheres from mouse embryonic stem cells by coculture with PA6 stromal cells.2005

    • Author(s)
      Kitajima H, Yosbimura S, Iwama T, et al.
    • Journal Title

      Journal of Neuroscience Research 80

      Pages: 467-474

    • Data Source
      KAKENHI-PROJECT-16390406
  • [Journal Article] Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells.

    • Author(s)
      Soeda A, Inagaki A, Oka N, Ikegame Y, Aoki H, Yoshimura S, Nakashima S, Kunisada T, Iwama T
    • Journal Title

      J Biol Chem (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659362
  • [Journal Article] The Growth Factor Progranulin Attenuates Neuronal Injury Induced by Cerebral Ischemia-Reperfusion Through the Suppression of Neutrophil Recruitment

    • Author(s)
      Egashira Y, Suzuki Y, Azuma Y, Mishiro K, Sugitani S, Tsuruma K, Shimazawa M, Yoshimura S, Kashimata M, Iwama T, Hara H
    • Journal Title

      J Neuroinflammation

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Presentation] The utility of XO-glioma stem cell lines for understanding of glioblastoma genesis2016

    • Author(s)
      Soeda A, Park DM, Iwama T
    • Organizer
      21st Annual Meeting and Education Day of the Society for Neuro-oncology
    • Place of Presentation
      Scottsdale
    • Year and Date
      2016-11-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670639
  • [Presentation] 悪性脳腫瘍幹細胞株XOシリーズから明らかとなった膠芽腫の病態と治療法2016

    • Author(s)
      副田明男, Park Deric, 岩間 亨
    • Organizer
      第75回日本脳神経外科学会学術総会
    • Place of Presentation
      福岡
    • Year and Date
      2016-09-29
    • Data Source
      KAKENHI-PROJECT-26670639
  • [Presentation] Long-term magnetic resonance angiography follow-up of recanalized vessels after mechanical clot extraction2013

    • Author(s)
      Enomoto Y,Yoshimura S,Egashira Y,Iwama T
    • Organizer
      International stroke conference 2013
    • Place of Presentation
      Honolulu
    • Data Source
      KAKENHI-PROJECT-24659646
  • [Presentation] The growth factor progranulin suppresses inflammatory reactions and attenuates neuronal injury induced by cerebral ischemia-reperfusion in mice2013

    • Author(s)
      Egashira Y,Sugitani S,Suzuki Y,Mishiro K,Tsuruma K,Shimazawa M,Yoshimura S,Iwama T,Hara H
    • Organizer
      International stroke conference 2013
    • Place of Presentation
      Honolulu
    • Data Source
      KAKENHI-PROJECT-24659646
  • [Presentation] The Growth Factor Progranulin Suppresses Inflammatory Reactions and Attenuates Neuronal Injury Induced by Focal Cerebral Ischemia/Reperfusion in Mice2013

    • Author(s)
      Egashira Y,Sugitani S, Suzuki Y, Mishiro K, Tsuruma K, Shimazawa M, Yoshimura S,Iwama T, Hara H
    • Organizer
      International Stroke Conference.Honolulu
    • Place of Presentation
      USA
    • Year and Date
      2013-02-06
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Presentation] マウス脳虚血モデルに対する成長因子プログラニュリンの保護作用2012

    • Author(s)
      江頭裕介, 杉谷 創, 鈴木悠起也, 鶴間一寛, 嶋澤雅光, 吉村紳一, 岩間 亨, 原 英彰
    • Organizer
      第24回日本脳循環代謝学会総会
    • Place of Presentation
      広島
    • Year and Date
      2012-11-08
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Presentation] Correlation between light transmission aggregometry and VerifyNow assay in the patients undergoing neuroendovascular therapy.2012

    • Author(s)
      Enomoto Y, Yoshimura S, Iwama T(Free paper)
    • Organizer
      10th Meeting of Asian-Australasian federation of interventional and therapeutic neuroradiology
    • Place of Presentation
      Nagoya
    • Data Source
      KAKENHI-PROJECT-24659646
  • [Presentation] Correlation between light transmission aggregometry and VerifyNow assay in the patients undergoing neuroendovascular therapy2012

    • Author(s)
      Enomoto Y,Yoshimura S,Iwama T
    • Organizer
      10th Meeting of Asian-Australasian federation of interventional and therapeutic neuroradiology
    • Place of Presentation
      Nagoya(Free paper)
    • Data Source
      KAKENHI-PROJECT-24659646
  • [Presentation] マウス脳梗塞モデルに対する脂肪組織由来幹細胞培養上清の保護作用2012

    • Author(s)
      江頭裕介, 杉谷 創, 鶴間一寛, 嶋澤雅光, 吉村紳一, 岩間 亨, 原 英彰
    • Organizer
      第71回日本脳神経外科学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2012-10-19
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Presentation] マウス脳虚血モデルに対する脂肪組織由来幹細胞培養上清の保護作用2011

    • Author(s)
      江頭裕介, 杉谷 創, 鈴木悠希也, 鶴間一寛, 嶋澤雅光 吉村紳一, 岩間 亨, 原 英彰
    • Organizer
      第23回日本脳循環代謝学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Presentation] マウス中大脳動脈虚血再灌流モデルに対するtPAとシロスタゾールの併用療法の検討2010

    • Author(s)
      石黒光紀, 三代圭祐, 藤原泰之, 陳 華岳, 伊豆田洋志, 鶴間一寛, 嶋澤雅光, 吉村紳一. 佐藤雅彦, 岩間 亨, 原 英彰
    • Organizer
      第22回日本脳循環代謝学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-27
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Presentation] マウス中大脳動脈虚血再灌流モデルに対するrt-PAとシロスタゾールの併用療法の検討2010

    • Author(s)
      石黒光紀, 嶋澤雅光, 吉村紳一, 岩間 亨, 原 英彰
    • Organizer
      第35回日本脳卒中学会総会
    • Place of Presentation
      盛岡
    • Year and Date
      2010-04-16
    • Data Source
      KAKENHI-PROJECT-22390274
  • [Presentation] 動脈狭窄症におけるプラーク診断 : その方法と治療法選択の現伏.2008

    • Author(s)
      吉村紳一, 岩間亨
    • Organizer
      第97回日本病理学会
    • Place of Presentation
      石川
    • Year and Date
      2008-05-16
    • Data Source
      KAKENHI-PROJECT-19659361
  • [Presentation] バルーンアシストテクニックの実際とその治療成績.2008

    • Author(s)
      吉村紳一, 榎本由貴子, 山田清文, 岩間亨
    • Organizer
      第24回日本脳神経血管内治療学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-11-13
    • Data Source
      KAKENHI-PROJECT-19659361
  • [Presentation] 血管内皮成長因子VEGFの膠芽腫腫瘍幹細胞に対する腫瘍形成や血管増生促進効果2007

    • Author(s)
      岡 直樹, 副田明男, 稲垣亮仁, 小野寺雅史, 丸山英和, 原 明, 国貞隆弘, 森 秀樹, 岩間 亨
    • Organizer
      第8回日本分子脳神経外科学会
    • Place of Presentation
      兵庫県
    • Year and Date
      2007-08-31
    • Data Source
      KAKENHI-PROJECT-19659362
  • [Presentation] Different tumor-initiating cells from a IDH1 wt glioblastoma patient.

    • Author(s)
      Soeda A, Hara A, Kunisada T, Iwama T
    • Organizer
      American Association for Cancer Research 2014
    • Place of Presentation
      San Diego(米国)
    • Year and Date
      2014-04-05 – 2014-04-09
    • Data Source
      KAKENHI-PROJECT-26670639
  • 1.  YOSHIMURA Shinichi (40240353)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 37 results
  • 2.  SAKAI Noboru (10021487)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  ENOMOTO Yukiko (20377659)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 14 results
  • 4.  SHINODA Jun (50273131)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  KAKU Yasuhiko (90242718)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  YANO Hirohito (00332685)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  OHE Naoyuki (60362159)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 8.  EGASHIRA Yusuke (50547677)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 13 results
  • 9.  NAKAYAMA Noriyuki (30444277)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  SOEDA Akio (20444276)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 11.  庄田 健二 (00866981)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  BANNO Yoshiko (50116852)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  NAKASHIMA Shigeru (60188935)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  加藤 雅康 (60345783)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  北島 英臣 (90377656)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  山田 清文 (40402200)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 17.  辻本 真範 (70509554)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 18.  山内 圭太 (10452153)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  宮居 雅文 (60613502)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 20.  山田 哲也 (60816114)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  木下 喬公 (40866977)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  熊谷 昌紀 (50973369)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  TANAKA Yoshitaka (00402199)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 24.  IKEGAME Yuka (50402201)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 25.  YOSHIMI Naoki (30166996)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  NODA Shinji (70303500)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  西村 康明 (60198512)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  中村 浩幸 (10211434)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  伊藤 和夫 (60093184)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  森下 竜一 (40291439)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  安藤 弘道 (60377661)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  高木 俊範 (00452152)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  竹中 勝信 (00283292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  上田 竜也 (60283305)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  澤田 重信 (40610415)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  船津 奈保子 (10550296)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  松原 博文 (00800244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 38.  富田 弘之 (50509510)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 39.  岡田 英志 (30402176)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 40.  鈴木 浩大
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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