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Fujiwara Masakazu  藤原 正和

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… Alternative Names

藤原 正和  フジワラ マサカズ

FUJIWARA Masakazu  藤原 正和

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Researcher Number 20312069
Other IDs
Affiliation (Current) 2025: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員
Affiliation (based on the past Project Information) *help 2025: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員
2022 – 2023: 埼玉医科大学, 医学部, 講師
2008 – 2009: Nippon Medical School, 老人病研究所, 助教
1999 – 2005: 日本医科大学, 老人病研究所, 助手
Review Section/Research Field
Principal Investigator
Basic Section 55020:Digestive surgery-related / General anatomy (including Histology/Embryology) / Human pathology
Except Principal Investigator
Respiratory organ internal medicine / Basic Section 46020:Anatomy and histopathology of nervous system-related / Respiratory organ internal medicine
Keywords
Principal Investigator
血管内皮細胞 / 血管形成 / 血管新生 / 形態形成学 / 発生学 / vWf / thrombomcdulin / jung / endothelial cells / von Willebrand factor / thrombomodulin / lung … More
Except Principal Investigator
… More トロンボモジュリン / トロンビン / セリンプロテアーゼ / 血管内皮細胞 / 遺伝子改変マウス / ペプチド / アミロイドβ蛋白 / アミロイド前駆体蛋白 / アポリポプロテインE / アルツハイマー病 / serine protease / lung injury / lung adenocarcinoma / thrombin / thrombomodulin / protease-activated receptor / vascular endothelial cell / alveolar capillary / マトリジェル / 抗凝固因子 / 凝固因子 / 内皮細胞 / 肺動脈 / 気管支動脈 / 肺微小血管 / RT-PCR / confocal laser scanning microscope / laser capture microdissection / Flt / KDR / VEGF / 肺傷害 / 肺腺癌 / プロテアーゼ活性化受容体 / 肺胞毛細血管 / サイトケラチン17 / サイトケラチン14 / 気道上皮系基底膜 / VII型コラーゲン / クララ細胞 / 肺胞上皮幹細胞 / 肺腺癌前駆細胞 / 気道上皮幹細胞 / 血液凝固 / 肺線維症 / 肺損傷治癒 / 膠原病性肺疾患 / 血液凝固因子 / 肺胞壁線維化 / 線維芽細胞 Less
  • Research Projects

    (7 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (10 People)
  •  膵癌細胞の上皮間葉系の多様性に基づく新規治療法の探索Principal Investigator

    • Principal Investigator
      藤原 正和
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Tokyo Metropolitan Institute for Geriatrics and Gerontology
  •  Targeting apolipoprotein E for Alzheimer's disease therapy.

    • Principal Investigator
      森 隆
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 46020:Anatomy and histopathology of nervous system-related
    • Research Institution
      Saitama Medical University
  •  Functional and molecular analysis of DSCR1 as a regulator of vascular morphologyPrincipal Investigator

    • Principal Investigator
      FUJIWARA Masakazu
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Nippon Medical School
  •  ヒト気道-肺胞上皮系における幹細胞の免疫組織学的同定と分離培養

    • Principal Investigator
      川並 汪一
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nippon Medical School
  •  肺胞壁の繊維過程における血管内皮細胞の役割について

    • Principal Investigator
      KAWANAMI Oichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nippon Medical School
  •  肺微小血管内皮細胞の分子生物学的レベルでの特徴づけPrincipal Investigator

    • Principal Investigator
      藤原 正和
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Human pathology
    • Research Institution
      Nippon Medical School
  •  Evaluations of Specific Endothelial Cell Markers in Lung Alveolar Capillaries

    • Principal Investigator
      KAWANAMI Oichi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Nippon Medical School

All 2023 2022 2009 2008 2005 2004

All Journal Article Presentation

  • [Journal Article] Targeting apolipoprotein E and N-terminal amyloid β-protein precursor interaction improves cognition and reduces amyloid pathology in Alzheimer’s mice.2023

    • Author(s)
      Darrell Sawmiller, Naoki Koyama, Masakazu Fujiwara, Tatsuya Segawa, Masahiro Maeda, Takashi Mori
    • Journal Title

      J Biol Chem

      Volume: 299, 7 Issue: 7 Pages: 104846-104846

    • DOI

      10.1016/j.jbc.2023.104846

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06460
  • [Journal Article] Expression of down syndrome critical region 1 represses vascular branching in Xenopus laevis larvae2008

    • Author(s)
      Fujiwara Masakazu
    • Journal Title

      J Nippon Med Sch 75巻

      Pages: 62-4

    • NAID

      130004057326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790168
  • [Journal Article] Dynamic and complex cell movement during formation of vascular structures studied with the fibrin bead assay2008

    • Author(s)
      Fujiwara Masakazu
    • Journal Title

      J Nippon Med Sch 75

      Pages: 194-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790168
  • [Journal Article] Expression of down syndrome critical region 1 represses vascular branching in Xenopus laevis larva2008

    • Author(s)
      Fujiwara Masakazu
    • Journal Title

      J Nippon Med Sch 75

      Pages: 62-4

    • NAID

      130004057326

    • Data Source
      KAKENHI-PROJECT-20790168
  • [Journal Article] Dynamic and complex movement during formation of vascular structures studied with the fibrin bead assay2008

    • Author(s)
      Fujiwara Masakazu、Ghazizadeh Mohammad、Kawanami Oich
    • Journal Title

      J Nippon Med Sch 75巻

      Pages: 194-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790168
  • [Journal Article] Activation of PAR4 induces a distinct antin fiber formation via p38 MAPK in human lung endothelial cells.2005

    • Author(s)
      Masakazu Fujiwara
    • Journal Title

      J Histochem Cytochem 53(9)

      Pages: 1121-1129

    • Data Source
      KAKENHI-PROJECT-15659199
  • [Journal Article] Differential expression of protease-activated receptors 1,2, and 4 on human endothelial cells from different vascular sites2004

    • Author(s)
      Fujiwara Masakazu
    • Journal Title

      Pathobiology 71・52

      Pages: 52-58

    • Data Source
      KAKENHI-PROJECT-15659199
  • [Presentation] アポリポ蛋白E-アミロイド前駆体蛋白結合を標的としたアルツハイマー病の新規治療法.2023

    • Author(s)
      森 隆,Darrell Sawmiller,小山直基,瀬川辰也,前田雅弘,藤原正和
    • Organizer
      第42回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K06460
  • [Presentation] アポリポ蛋白E-アミロイド前駆体蛋白結合を標的としたアルツハイマー病の治療法の開発.2023

    • Author(s)
      藤原正和,小山直基,森 隆
    • Organizer
      第70回日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-22K06460
  • [Presentation] 新規アルツハイマー病治療薬:アポリポ蛋白E由来ペプチド2022

    • Author(s)
      小山直基、藤原正和,森 隆
    • Organizer
      第69回日本実験動物学会
    • Data Source
      KAKENHI-PROJECT-22K06460
  • [Presentation] アポリポ蛋白E-アミロイド前駆体蛋白結合阻害剤(6KApoEp)によるアルツハイマー様病態の改善効果2022

    • Author(s)
      藤原正和,小山直基、森 隆
    • Organizer
      第69回日本実験動物学会
    • Data Source
      KAKENHI-PROJECT-22K06460
  • [Presentation] VEGFによって誘導される遺伝子の血管形態における役割2009

    • Author(s)
      藤原正和
    • Organizer
      第17回日本血管生物医学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20790168
  • [Presentation] Down syndrome critical region 1 represses vascular branching in Xenopus laevis larvae2008

    • Author(s)
      Fujiwara Masakazu
    • Organizer
      International Vascular Biology Meeting
    • Place of Presentation
      Sydney
    • Data Source
      KAKENHI-PROJECT-20790168
  • [Presentation] Overexpression of regulator of calcineurin 1 represses vascular branching in Xenopus laevis larvae2008

    • Author(s)
      Fujiwara Masakazu
    • Organizer
      The 6th Korea-Japan Symposium on Vascular Biology
    • Place of Presentation
      Kanazawa, Japan
    • Data Source
      KAKENHI-PROJECT-20790168
  • [Presentation] Down Syndrome Critical Region 1 Represses Vascular Branching in Xenopus laevis Larvae2008

    • Author(s)
      Fujiwara Masakazu
    • Organizer
      International Vascular Biology Meeting
    • Place of Presentation
      Sydney
    • Data Source
      KAKENHI-PROJECT-20790168
  • [Presentation] Overexpression of Regulator of Calcineurin 1 Represses Vascular Branching in Xenopus laevis Larvae2008

    • Author(s)
      Fujiwara Masakazu
    • Organizer
      The 6th Korea-Japan Joint Symposium on Vascular Biology
    • Place of Presentation
      Kanazawa
    • Data Source
      KAKENHI-PROJECT-20790168
  • 1.  GHAZIZADEH Mohammad (30190979)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 2.  KAWANAMI Oichi (70096973)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  JIN Enjing (10312068)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  EMI Mitsuru (90221118)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  OHTA Shigeo (00125832)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  立原 章年 (60350071)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  大國 寿士 (60060365)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  森 隆 (60239605)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 9.  百瀬 修二 (70360344)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  横尾 友隆 (80400688)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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