Fujiwara Masakazu 藤原正和

… Alternative Names

藤原正和フジワラマサカズ

FUJIWARA Masakazu 藤原正和

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Researcher Number	20312069
Other IDs
Affiliation (Current)	2025: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究員
Affiliation (based on the past Project Information) *help	2025: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究員 2022 – 2023: 埼玉医科大学, 医学部, 講師 2008 – 2009: Nippon Medical School, 老人病研究所, 助教 1999 – 2005: 日本医科大学, 老人病研究所, 助手
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / General anatomy (including Histology/Embryology) / Human pathology Except Principal Investigator Respiratory organ internal medicine / Basic Section 46020:Anatomy and histopathology of nervous system-related / Respiratory organ internal medicine
Keywords	Principal Investigator スフェロイド / 抗癌剤治療 / 上皮間葉系転換 / 3次元培養 / 膵臓がん / 血管内皮細胞 / 血管形成 / 血管新生 / 形態形成学 / 発生学 … More / vWf / thrombomcdulin / jung / endothelial cells / von Willebrand factor / thrombomodulin / lung … More Except Principal Investigator トロンボモジュリン / トロンビン / セリンプロテアーゼ / 血管内皮細胞 / 遺伝子改変マウス / ペプチド / アミロイドβ蛋白 / アミロイド前駆体蛋白 / アポリポプロテインE / アルツハイマー病 / serine protease / lung injury / lung adenocarcinoma / thrombin / thrombomodulin / protease-activated receptor / vascular endothelial cell / alveolar capillary / マトリジェル / 抗凝固因子 / 凝固因子 / 内皮細胞 / 肺動脈 / 気管支動脈 / 肺微小血管 / RT-PCR / confocal laser scanning microscope / laser capture microdissection / Flt / KDR / VEGF / 肺傷害 / 肺腺癌 / プロテアーゼ活性化受容体 / 肺胞毛細血管 / サイトケラチン17 / サイトケラチン14 / 気道上皮系基底膜 / VII型コラーゲン / クララ細胞 / 肺胞上皮幹細胞 / 肺腺癌前駆細胞 / 気道上皮幹細胞 / 血液凝固 / 肺線維症 / 肺損傷治癒 / 膠原病性肺疾患 / 血液凝固因子 / 肺胞壁線維化 / 線維芽細胞 Less

膵癌細胞の上皮間葉系の多様性に基づく新規治療法の探索Principal Investigator
- Principal Investigator
  
  藤原正和
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tokyo Metropolitan Institute for Geriatrics and Gerontology
Targeting apolipoprotein E for Alzheimer's disease therapy.
- Principal Investigator
  
  森隆
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46020:Anatomy and histopathology of nervous system-related
- Research Institution
  Saitama Medical University
Functional and molecular analysis of DSCR1 as a regulator of vascular morphologyPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Masakazu
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Nippon Medical School
ヒト気道-肺胞上皮系における幹細胞の免疫組織学的同定と分離培養
- Principal Investigator
  
  川並汪一
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
肺胞壁の繊維過程における血管内皮細胞の役割について
- Principal Investigator
  
  KAWANAMI Oichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
肺微小血管内皮細胞の分子生物学的レベルでの特徴づけPrincipal Investigator
- Principal Investigator
  
  藤原正和
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human pathology
- Research Institution
  Nippon Medical School
Evaluations of Specific Endothelial Cell Markers in Lung Alveolar Capillaries
- Principal Investigator
  
  KAWANAMI Oichi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School

All 2023 2022 2009 2008 2005 2004

All Journal Article Presentation

[Journal Article] Targeting apolipoprotein E and N-terminal amyloid β-protein precursor interaction improves cognition and reduces amyloid pathology in Alzheimer’s mice.2023
- Author(s)
  Darrell Sawmiller, Naoki Koyama, Masakazu Fujiwara, Tatsuya Segawa, Masahiro Maeda, Takashi Mori
- Journal Title
  
  J Biol Chem
  
  Volume: 299, 7 Issue: 7 Pages: 104846-104846
- DOI
  10.1016/j.jbc.2023.104846
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06460
[Journal Article] Expression of down syndrome critical region 1 represses vascular branching in Xenopus laevis larvae2008
- Author(s)
  Fujiwara Masakazu
- Journal Title
  
  J Nippon Med Sch 75巻
  
  Pages: 62-4
- NAID
  130004057326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790168
[Journal Article] Dynamic and complex cell movement during formation of vascular structures studied with the fibrin bead assay2008
- Author(s)
  Fujiwara Masakazu
- Journal Title
  
  J Nippon Med Sch 75
  
  Pages: 194-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790168
[Journal Article] Expression of down syndrome critical region 1 represses vascular branching in Xenopus laevis larva2008
- Author(s)
  Fujiwara Masakazu
- Journal Title
  
  J Nippon Med Sch 75
  
  Pages: 62-4
- NAID
  130004057326
- Data Source
  KAKENHI-PROJECT-20790168
[Journal Article] Dynamic and complex movement during formation of vascular structures studied with the fibrin bead assay2008
- Author(s)
  Fujiwara Masakazu、Ghazizadeh Mohammad、Kawanami Oich
- Journal Title
  
  J Nippon Med Sch 75巻
  
  Pages: 194-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790168
[Journal Article] Activation of PAR4 induces a distinct antin fiber formation via p38 MAPK in human lung endothelial cells.2005
- Author(s)
  Masakazu Fujiwara
- Journal Title
  
  J Histochem Cytochem 53(9)
  
  Pages: 1121-1129
- Data Source
  KAKENHI-PROJECT-15659199
[Journal Article] Differential expression of protease-activated receptors 1,2, and 4 on human endothelial cells from different vascular sites2004
- Author(s)
  Fujiwara Masakazu
- Journal Title
  
  Pathobiology 71・52
  
  Pages: 52-58
- Data Source
  KAKENHI-PROJECT-15659199
[Presentation] アポリポ蛋白E-アミロイド前駆体蛋白結合を標的としたアルツハイマー病の新規治療法．2023
- Author(s)
  森　隆，Darrell Sawmiller，小山直基，瀬川辰也，前田雅弘，藤原正和
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06460
[Presentation] アポリポ蛋白E-アミロイド前駆体蛋白結合を標的としたアルツハイマー病の治療法の開発．2023
- Author(s)
  藤原正和，小山直基，森　隆
- Organizer
  第70回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-22K06460
[Presentation] 新規アルツハイマー病治療薬：アポリポ蛋白E由来ペプチド2022
- Author(s)
  小山直基、藤原正和，森　隆
- Organizer
  第69回日本実験動物学会
- Data Source
  KAKENHI-PROJECT-22K06460
[Presentation] アポリポ蛋白E-アミロイド前駆体蛋白結合阻害剤（6KApoEp）によるアルツハイマー様病態の改善効果2022
- Author(s)
  藤原正和，小山直基、森　隆
- Organizer
  第69回日本実験動物学会
- Data Source
  KAKENHI-PROJECT-22K06460
[Presentation] VEGFによって誘導される遺伝子の血管形態における役割2009
- Author(s)
  藤原正和
- Organizer
  第17回日本血管生物医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790168
[Presentation] Down syndrome critical region 1 represses vascular branching in Xenopus laevis larvae2008
- Author(s)
  Fujiwara Masakazu
- Organizer
  International Vascular Biology Meeting
- Place of Presentation
  Sydney
- Data Source
  KAKENHI-PROJECT-20790168
[Presentation] Overexpression of regulator of calcineurin 1 represses vascular branching in Xenopus laevis larvae2008
- Author(s)
  Fujiwara Masakazu
- Organizer
  The 6th Korea-Japan Symposium on Vascular Biology
- Place of Presentation
  Kanazawa, Japan
- Data Source
  KAKENHI-PROJECT-20790168
[Presentation] Down Syndrome Critical Region 1 Represses Vascular Branching in Xenopus laevis Larvae2008
- Author(s)
  Fujiwara Masakazu
- Organizer
  International Vascular Biology Meeting
- Place of Presentation
  Sydney
- Data Source
  KAKENHI-PROJECT-20790168
[Presentation] Overexpression of Regulator of Calcineurin 1 Represses Vascular Branching in Xenopus laevis Larvae2008
- Author(s)
  Fujiwara Masakazu
- Organizer
  The 6th Korea-Japan Joint Symposium on Vascular Biology
- Place of Presentation
  Kanazawa
- Data Source
  KAKENHI-PROJECT-20790168

1. GHAZIZADEH Mohammad (30190979)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. KAWANAMI Oichi (70096973)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. JIN Enjing (10312068)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. EMI Mitsuru (90221118)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OHTA Shigeo (00125832)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 立原章年 (60350071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 大國寿士 (60060365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 森隆 (60239605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. 百瀬修二 (70360344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 横尾友隆 (80400688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 石渡俊行 (90203041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Fujiwara Masakazu 藤原 正和

藤原 正和 フジワラ マサカズ

FUJIWARA Masakazu 藤原 正和

Research Projects

Research Products

Co-Researchers

膵癌細胞の上皮間葉系の多様性に基づく新規治療法の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Targeting apolipoprotein E for Alzheimer's disease therapy.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional and molecular analysis of DSCR1 as a regulator of vascular morphologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト気道-肺胞上皮系における幹細胞の免疫組織学的同定と分離培養

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肺胞壁の繊維過程における血管内皮細胞の役割について

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肺微小血管内皮細胞の分子生物学的レベルでの特徴づけPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluations of Specific Endothelial Cell Markers in Lung Alveolar Capillaries

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Targeting apolipoprotein E and N-terminal amyloid β-protein precursor interaction improves cognition and reduces amyloid pathology in Alzheimer’s mice.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of down syndrome critical region 1 represses vascular branching in Xenopus laevis larvae2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Dynamic and complex cell movement during formation of vascular structures studied with the fibrin bead assay2008

Author(s)

Journal Title

Data Source

[Journal Article] Expression of down syndrome critical region 1 represses vascular branching in Xenopus laevis larva2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Dynamic and complex movement during formation of vascular structures studied with the fibrin bead assay2008

Author(s)

Journal Title

Data Source

[Journal Article] Activation of PAR4 induces a distinct antin fiber formation via p38 MAPK in human lung endothelial cells.2005

Author(s)

Journal Title

Data Source

[Journal Article] Differential expression of protease-activated receptors 1,2, and 4 on human endothelial cells from different vascular sites2004

Author(s)

Journal Title

Data Source

[Presentation] アポリポ蛋白E-アミロイド前駆体蛋白結合を標的としたアルツハイマー病の新規治療法．2023

Fujiwara Masakazu 藤原正和

藤原正和フジワラマサカズ

FUJIWARA Masakazu 藤原正和