KAWAKAMI Shigeru 川上茂

Researcher Number	20322307
Other IDs
External Links
Affiliation (Current)	2025: 長崎大学, 医歯薬学総合研究科(薬学系), 教授
Affiliation (based on the past Project Information) *help	2014 – 2024: 長崎大学, 医歯薬学総合研究科(薬学系), 教授 2013: 長崎大学, 医歯(薬)学総合研究科, 教授 2013: 長崎大学, 医歯薬学総合研究科, 教授 2013: 長崎大学医歯薬学総合研究科, 医薬品情報学, 教授 2012: 京都大学, 薬学研究科(研究院), 講師 … More 2011: 京都大学, 大学院・薬学研究科, 講師 2009 – 2011: Kyoto University, 薬学研究科, 講師 2007 – 2008: Kyoto University, 薬学研究科, 助教 2003 – 2006: 京都大学, 薬学研究科, 助手 2002 – 2003: 京都大学, 大学院・薬学研究科, 助手 2000 – 2001: 長崎大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Medical pharmacy / Basic Section 90120:Biomaterials-related / Medium-sized Section 90:Biomedical engineering and related fields / Pharmaceutical Sciences and related fields / Biological Sciences / Physical pharmacy / Applied pharmacology Except Principal Investigator Medical pharmacy / Biological Sciences / Medium-sized Section 90:Biomedical engineering and related fields … More / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 47060:Clinical pharmacy-related / Physical pharmacy / Biomedical engineering/Biological material science / Basic Section 56010:Neurosurgery-related / Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 90120:Biomaterials-related / Radiation science / Physical pharmacy Less
Keywords	Principal Investigator ドラッグデリバリーシステム / ターゲティング / リポソーム / 遺伝子治療 / 遺伝子デリバリー / 癌 / マンノース修飾リポソーム / DNAワクチン / 多色深部イメージング / 標的指向化 … More / 組織吸引圧法 / 組織押圧法 / 腫瘍関連マクロファージ / 超音波 / ドラッグデリバリー / 遺伝子 / 医療・福祉 / 樹状細胞 / カチオン性リポソーム / 脳 / ゲノム編集 / 細胞外小胞 / 脂質ナノ粒子 / mRNA / ワクチン / ドラッグデリバリーシステム(DDS) / がん / tissue cleaning / mechanobiology / gene delivery / gene therapy / transfection / トランスフェクション / 組織透明化 / メカノセンサー分子 / メカノトランスフェクション / バイオ関連機器 / バイオテクノロジー / ドキソルビシン / ヘマトポルフィリン / 製剤学 / 生体機能利用 / 薬学 / マクロファージ / 癌治療 / 核酸医薬品 / バブルリポソーム / 糖修飾リポソーム / がん治療 / ＤＤＳ / 組織押圧核酸導入法 / in vivo長期遺伝子発現 / 遺伝子機能解析 / 組織核酸導入法 / phiC31インテグラーゼ / 長期遺伝子発現系 / 長期発現 / 腎臓 / 肝臓 / 遺伝子導入 / DDS / 非ウイルスキャリア / ソノポレーション / メラノーマ / 免疫学 / 体内動態 / 受容体介在型エンドサイトーシス / プラスミドDNA / マンノースレセプター … More Except Principal Investigator 遺伝子デリバリー / ドラッグデリバリー / ターゲティング / NFκB / siRNA / 核酸医薬 / ドラッグデリバリーシステム / ナノ微粒子 / Drug delivery system / リポソーム / 癌 / 遺伝子治療 / DDS / 脂質ナノ粒子 / NO / Drug targeting / 抗癌剤 / 肝臓 / がん治療 / プラスミドDNA / カタラーゼ / 癌転移 / カチオン性リポソーム / LNP / mRNA / malignant brain tumor / 脳指向薬物送達法 / 集束超音波 / 悪性神経膠腫 / 抗体 / 網膜 / 核酸送達 / 人工受容体 / 腫瘍溶解性ウイルス / 家族性地中海熱 / アップコンバージョン / 光線力学療法 / 無機ナノ粒子 / アップコンバージョン効果 / マルチステップ作用 / コレステロール / アミロイドβペプチド / siRNA複合体 / 脳アミロイドーシス / ゲノム編集 / 脳移行 / 脳移行性リガンド / 結合体 / シクロデキストリン / デンドリマー / 血液脳関門 / 多段階作用 / アルツハイマー病 / DNAワクチン / 肺がん / メラノーマ / 遺伝子・核酸医薬 / 経肺投与 / テロメラーゼ / RGD / Mucin-16 / NQO1 / 標的指向化リポソーム / トリプルネガティブ乳がん / ペプチド / 標的指向化 / トリプルネガティブ乳癌 / 内用放射線治療薬剤 / orally active drugs / P-glycoprotein / drug-likeness / pattern recognition / information visualization / chemical space / structure-activity relationship / トランスポータ / 化合物超空間 / P糖タンパク質 / 経口医薬品 / P-糖タンパク質 / ドラッグライクネス / 判別分析 / 情報可視化 / 化合物特性空間 / 構造活性相関 / Reactive oxygen / Non-viral vector / Gene therapy / Gene delivery / Plasmid DNA / 核移行シグナル / 化学修飾 / NF-κB / キメラタンパク質 / 活性酸素 / 非ウイルスベクター / oharmacokinetics / absorption rate / intraperitoneal administration / liver disease / anticancer drug / liver / 薬物速度論 / 吸収速度 / 腹腔内投与 / 肝疾患 / 抗癌薬 / Cancer chemotherapy / Anticancer agent / Rat / 5-Fluorouracil / Liver surface application / Liver / 癌化学療法 / 制癌剤 / ラット / 5-fluorouracil / 肝臓表面投与 / 薬物送達 / 超音波 / 細胞膜表面修飾 / PEG脂質 / 幹細胞 / ナノ粒子 / がん微小環境 / 超音波医科学 / ナノバイオ材料 / 小胞体ストレス / 免疫活性化 / 核酸医療 / chondroitin sulfate / γ-polyglutamic acid / アニオン性高分子 / 遺伝子導入 / カチオン性遺伝子ベクター / 低分子リガンド / 静電的相互作用 / 遺伝子導入技術 / 自己組織化 / 生体分解型ベクター / 生体適合型ベクター / グリチルリチン / 葉酸 / ナノ材料 / 遺伝子 / 非ウィルス性キャリア / プロトンスボンジ効果 / NFkB / 免疫応答 / ポリマー / エンドソーム / サイトカイン / Kupffer細胞 / 炎症性サイトカイン / NFκBデコイ / 移植片拒絶 / 高分子ミセル / リボソーム / 活性酸素消去酵素 / がん / CpG / 量子ドット / 腹膜播種 / レチノイン酸誘導体 / 分化誘導量表 / CpGオリゴ / 免疫療法 / 薬物キャリア / イメージング / 癌ターゲティング / マクロファージ / ルシフェラーゼ / デリバリー / マトリックスメタロプロテアーゼ / 活性酵素消去酵素 / 転移性肺癌 / インターフェロン-β / 構造解析 / 原子間力顕微鏡 / X線小角散乱法 / 癌遺伝子治療 Less

ナノリポソームを用いたドラッグデリバリーによる自己炎症性疾患の治療戦略
- Principal Investigator
  
  梅田雅孝
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nagasaki University
Efficient Drug Targeting by oncolytic virus-meidated tumor-specific expression of artificial receptors
- Principal Investigator
  
  櫻井文教
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kindai University
網膜への低侵襲的局所投与型核酸送達システムの創製
- Principal Investigator
  
  高島由季
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Juntendo University
Development of nucleic acid drug delivery and genome editing technologies for various cells in the brainPrincipal Investigator
- Principal Investigator
  
  川上茂
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Nagasaki University
悪性神経膠腫に対するsiRNAを使用した核酸医薬導入への挑戦
- Principal Investigator
  
  松尾彩香
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nagasaki University
Development of a non-invasive delivery method for mRNA drugs for malignant brain tumors
- Principal Investigator
  
  日宇健
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagasaki University
Development of innovative T cell-inducing vaccine drug based on mRNA deliveryPrincipal Investigator
- Principal Investigator
  
  Kawakami Shigeru
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Nagasaki University
アップコンバージョンナノ粒子を基盤とした光線力学療法用製剤の開発
- Principal Investigator
  
  毛利浩太
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nagasaki University
  Institute of Physical and Chemical Research
Development of gene and nucleic acid medicines for lung cancer based on the multifunctional pulmonary nanoparticles
- Principal Investigator
  
  Kodama Yukinobu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagasaki University
Development of innovative drugs having multistep action for treatment of central cerebral amyloidosis
- Principal Investigator
  
  Hidetoshi Arima
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
Development of new nucleic acid medicines for intractable respiratory diseases
- Principal Investigator
  
  SASAKI Hitoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagasaki University
Development of multi color deep imaging of cancer tissues and spatial distribution control of drug deliveryPrincipal Investigator
- Principal Investigator
  
  Kawakami Shigeru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Nagasaki University
Development of nanocarrier-based internal radiation therapiutic reagent for breast cancer
- Principal Investigator
  
  HAGIMORI Masayori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Nagasaki University
Elucidation of mechano-transfection and mechano-sensing mechanism using a living tissuePrincipal Investigator
- Principal Investigator
  
  KAWAKAMI Shigeru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Pharmaceutical Sciences and related fields
- Research Institution
  Nagasaki University
Development of gene delivery system using the tissue press/suction methodPrincipal Investigator
- Principal Investigator
  
  KAWAKAMI Shigeru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagasaki University
超音波増感剤封入マンノース修飾リポソームによる発がんスパイラル制御法の開発Principal Investigator
- Principal Investigator
  
  川上茂
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki University
Development of cell surface modification with PEGylated lipid and external stimulation
- Principal Investigator
  
  HIGUCHI Yuriko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kyoto University
Therapeutic strategy of drug delivery systems utilizing unique tumor environment
- Principal Investigator
  
  HASHIDA Mitsuru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kyoto University
Development of tumor associated macrophages-selective DDS and its application to tumor therapyPrincipal Investigator
- Principal Investigator
  
  KAWAKAMI Shigeru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
  Kyoto University
Development of long-term protein expression for medical application of gene delivery technology and its therapeutic applicationPrincipal Investigator
- Principal Investigator
  
  KAWAKAMI Shigeru
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto University
The development of self-assembly nano-devices based on electrostatic interaction and the application to selective drug delivery
- Principal Investigator
  
  SASAKI Hitoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
Development of efficient gene transfection system by the combination use of dendritic cells-selective nanoparticle and physical stimulation for cancer therapyPrincipal Investigator
- Principal Investigator
  
  KAWAKAMI Shigeru
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
Development of gene carriers based on in vivo and intracellular distribution real-time analysis
- Principal Investigator
  
  MITSURU Hashida
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
Development of bioimaging method and targeted drug delivery system for inhibiting tumor proliferation and metastasis
- Principal Investigator
  
  HASHIDA Mitsuru
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
NFκB活性化抑制に基づく新しい臓器移植における拒絶抑制法の開発
- Principal Investigator
  
  橋田充
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
樹状細胞指向型リポソームを用いた新規DNAワクチン療法の開発Principal Investigator
- Principal Investigator
  
  川上茂
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
活性酸素消去酵素の細胞選択的ターゲティング・遺伝子導入によるがん転移抑制
- Principal Investigator
  
  橋田充
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
細胞特異的遺伝子導入キャリアを用いた新規細胞性免疫型DNAワクチンの構築Principal Investigator
- Principal Investigator
  
  川上茂
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
Strategy for optimization of in vivo gene delivery based on systemic control of delivery and transfection
- Principal Investigator
  
  HASHIDA Mitsuru
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
Development of Novel Discrimination Model and Its Application to Predicting P-gp Substrate
- Principal Investigator
  
  YAMASHITA Fumiyoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
Targeting of anticancer drugs and genome medicine by utilizing absorption from the liver surface
- Principal Investigator
  
  NISHIDA Koyo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
Liver-selective delivery of 5-fluorouracil utilizing the absorption on the liver surface in rats
- Principal Investigator
  
  NAKAMURA Junzo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
がん遺伝子治療の基盤となる遺伝子in vivoデリバリー法の開発
- Principal Investigator
  
  HASHIDA Mitsuru
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University

[Book] 創薬研究者・アカデミア研究者が知っておくべき最新の免疫学とその応用技術2021
- Author(s)
  加藤直也, 増田智成, 向井英史, 川上茂　他、技術情報協会
- Total Pages
  598
- Publisher
  技術情報協会
- ISBN
  9784861048562
- Data Source
  KAKENHI-PROJECT-18H03535
[Book] バイオ医薬の開発技術とシーズ、第5編非感染症ワクチン(がんワクチン他)、第3章がんDNAワクチンの為のリポソーム製剤の開発2008
- Author(s)
  川上茂、樋口ゆり子、橋田充
- Publisher
  CMC出版社
- Data Source
  KAKENHI-PROJECT-19689005
[Book] バイオ医薬の開発技術とシーズ(第5編非感染症ワクチン(がんワクチン他)、第3章がんDNAワクチンの為のリポソーム製剤の開発)2008
- Author(s)
  川上茂、樋口ゆり子、橋田充
- Publisher
  CMC出版社
- Data Source
  KAKENHI-PROJECT-19689005
[Book] Liposomal in vivo gene delivery2005
- Author(s)
  S.Kawakami
- Total Pages
  12
- Publisher
  Wiley-VCH, Verlag GmbH & Co.KgaA, Weinheim
- Data Source
  KAKENHI-PROJECT-15209006
[Book] Liposomal in vivo gene deivery2005
- Author(s)
  S.Kawakami et al.
- Total Pages
  12
- Publisher
  Wiley-VCH, Verlag GmbH & Co. KgaA, Weinheim
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209006
[Book] Non-viral gene therapy, "In vivo gene transfer by ligand-modified gene carriers" (K.Taira, K.Kataoka, T.Niidome (Ed.))2005
- Author(s)
  Shigeru Kawakami et al.
- Total Pages
  11
- Publisher
  Springer-Verlag Tokyo
- Data Source
  KAKENHI-PROJECT-17790119
[Book] In vivo gene transfer by ligand-modified gene carriers2005
- Author(s)
  S.Kawakami
- Total Pages
  11
- Publisher
  Springer-Verlag Tokyo
- Data Source
  KAKENHI-PROJECT-17659046
[Journal Article] Influence of lipid composition of messenger RNA-loaded lipid nanoparticles on the protein expression via intratracheal administration in mice2023
- Author(s)
  Geng Longjian, Kato Naoya, Kodama Yukinobu, Mukai Hidefumi, Kawakami Shigeru
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 637 Pages: 122896-122896
- DOI
  10.1016/j.ijpharm.2023.122896
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20J21334, KAKENHI-PROJECT-21H03818
[Journal Article] Development of an apolipoprotein E mimetic peptide lipid conjugate for efficient brain delivery of liposomes2023
- Author(s)
  Kato Naoya, Yamada Sakura, Suzuki Rino, Iida Yoshiki, Matsumoto Makoto, Fumoto Shintaro, Arima Hidetoshi, Mukai Hidefumi, Kawakami Shigeru
- Journal Title
  
  Drug Delivery
  
  Volume: 30 Issue: 1 Pages: 2173333-2173333
- DOI
  10.1080/10717544.2023.2173333
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20J21334, KAKENHI-PROJECT-20H04540
[Journal Article] Investigation of enhanced intracellular delivery of nanomaterials modified with novel cell-penetrating zwitterionic peptide-lipid derivatives2023
- Author(s)
  Sugimoto Yuri、Suga Tadaharu、Umino Mizuki、Yamayoshi Asako、Mukai Hidefumi、Kawakami Shigeru
- Journal Title
  
  Drug Delivery
  
  Volume: 30 Issue: 1 Pages: 2191891-2191891
- DOI
  10.1080/10717544.2023.2191891
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05874, KAKENHI-PROJECT-22H00593, KAKENHI-PROJECT-21H03818
[Journal Article] Effect of Cholesterol Content of Lipid Composition in mRNA-LNPs on the Protein Expression in the Injected Site and Liver After Local Administration in Mice2023
- Author(s)
  Kawaguchi Maho、Noda Marin、Ono Akari、Kamiya Mariko、Matsumoto Makoto、Tsurumaru Masako、Mizukami Shusaku、Mukai Hidefumi、Kawakami Shigeru
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 112 Issue: 5 Pages: 1401-1410
- DOI
  10.1016/j.xphs.2022.12.026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03818
[Journal Article] Recent advances in lipid nanoparticles for delivery of nucleic acid, mRNA, and gene editing-based therapeutics2022
- Author(s)
  Mukai Hidefumi, Ogawa Koki, Kato Naoya, Kawakami Shigeru
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 44 Pages: 100450-100450
- DOI
  10.1016/j.dmpk.2022.100450
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20J21334, KAKENHI-PROJECT-21H03818
[Journal Article] Microfluidic Post-Insertion Method for the Efficient Preparation of PEGylated Liposomes Using High Functionality and Quality Lipids2022
- Author(s)
  Sugimoto Yuri、Suga Tadaharu、Kato Naoya、Umino Mizuki、Yamayoshi Asako、Mukai Hidefumi、Kawakami Shigeru
- Journal Title
  
  International Journal of Nanomedicine
  
  Volume: Volume 17 Pages: 6675-6686
- DOI
  10.2147/ijn.s390866
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05874, KAKENHI-PROJECT-22H00593, KAKENHI-PROJECT-21H03818, KAKENHI-PROJECT-20J21334
[Journal Article] Stability Study of mRNA-Lipid Nanoparticles Exposed to Various Conditions Based on the Evaluation between Physicochemical Properties and Their Relation with Protein Expression Ability2022
- Author(s)
  Kamiya Mariko、Matsumoto Makoto、Yamashita Kazuma、Izumi Tatsunori、Kawaguchi Maho、Mizukami Shusaku、Tsurumaru Masako、Mukai Hidefumi、Kawakami Shigeru
- Journal Title
  
  Pharmaceutics
  
  Volume: 14 Issue: 11 Pages: 2357-2357
- DOI
  10.3390/pharmaceutics14112357
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03818
[Journal Article] Focused ultrasound/microbubbles-assisted BBB opening enhances LNP-mediated mRNA delivery to brain2022
- Author(s)
  Ogawa Koki、Kato Naoya、Yoshida Michiharu、Hiu Takeshi、Matsuo Takayuki、Mizukami Shusaku、Omata Daiki、Suzuki Ryo、Maruyama Kazuo、Mukai Hidefumi、Kawakami Shigeru
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 348 Pages: 34-41
- DOI
  10.1016/j.jconrel.2022.05.042
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09328, KAKENHI-PROJECT-22K12849, KAKENHI-PROJECT-20H04519, KAKENHI-PROJECT-20H04542, KAKENHI-PROJECT-20H04554, KAKENHI-PROJECT-21H03818, KAKENHI-PROJECT-20J21334, KAKENHI-PROJECT-21K15554
[Journal Article] The current situation and perspectives of mRNA delivery to the kidney2022
- Author(s)
  Kawaguchi Maho、Kato Naoya、Kamiya Mariko、Mukai Hidefumi、Kawakami Shigeru
- Journal Title
  
  Drug Delivery System
  
  Volume: 37 Issue: 3 Pages: 253-262
- DOI
  10.2745/dds.37.253
- ISSN
  0913-5006, 1881-2732
- Year and Date
  2022-07-25
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03818, KAKENHI-PROJECT-20J21334
[Journal Article] Efficient Messenger RNA Delivery to the Kidney Using Renal Pelvis Injection in Mice2021
- Author(s)
  Oyama Natsuko、Kawaguchi Maho、Itaka Keiji、Kawakami Shigeru
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Issue: 11 Pages: 1810-1810
- DOI
  10.3390/pharmaceutics13111810
- NAID
  120007185291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03776, KAKENHI-PROJECT-21H03818
[Journal Article] mRNAワクチンの基幹技術：核酸デリバリーと脂質ナノ粒子2021
- Author(s)
  神谷万里子, 川上茂
- Journal Title
  
  科学
  
  Volume: 91 Pages: 1118-1122
- NAID
  40022749381
- Data Source
  KAKENHI-PROJECT-21H03818
[Journal Article] Evaluation of transgene expression characteristics and DNA vaccination against melanoma metastasis of an intravenously injected ternary complex with biodegradable dendrigraft poly-L-lysine in mice2021
- Author(s)
  Kodama Y, Tokunaga A, Hashizume J, Nakagawa H, Harasawa H, Kurosaki T, Nakamura T, Nishida K, Nakashima M, Hashida M, Kawakami S, Sasaki H.
- Journal Title
  
  Drug Delivery
  
  Volume: 28 Issue: 1 Pages: 542-549
- DOI
  10.1080/10717544.2021.1895904
- NAID
  120007150301
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07156
[Journal Article] Development of a DNA Vaccine for Melanoma Metastasis by Inhalation Based on an Analysis of Transgene Expression Characteristics of Naked pDNA and a Ternary Complex in Mouse Lung Tissues2020
- Author(s)
  Kodama Y, Nakashima M, Nagahara T, Oyama N, Hashizume J, Nakagawa H, Harasawa H, Muro T, Kurosaki T, Yamashita C, Hashida M, Kitahara T, Sasaki H, Kawakami S, Nakamura T
- Journal Title
  
  Pharmaceutics
  
  Volume: 12 Issue: 6 Pages: 540-540
- DOI
  10.3390/pharmaceutics12060540
- NAID
  120006988149
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07156, KAKENHI-PROJECT-18H02589
[Journal Article] Tissue suction-mediated gene transfer to the beating heart in mice2020
- Author(s)
  Yota Taniguchi, Natsuko Oyama, Shintaro Fumoto, Hideyuki Kinoshita, Fumiyoshi Yamashita, Kazunori Shimizu, Mitsuru Hashida, Shigeru Kawakami
- Journal Title
  
  PLoS ONE
  
  Volume: 15 Issue: 2 Pages: e0228203-e0228203
- DOI
  10.1371/journal.pone.0228203
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18J10186, KAKENHI-PROJECT-17K19496
[Journal Article] Effects of tissue pressure on transgene expression characteristics via renal local administration routes from ureter or renal artery in the rat kidney2020
- Author(s)
  Natsuko Oyama, Haruyuki Takahashi, Maho Kawaguchi, Hirotaka Miyamoto, Koyo Nishida, Masako Tsurumaru, Mikiro Nakashima, Fumiyoshi Yamashita, Mitsuru Hashida, Shigeru Kawakami
- Journal Title
  
  Pharmaceutics
  
  Volume: 12 Issue: 2 Pages: 114-114
- DOI
  10.3390/pharmaceutics12020114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18J10186, KAKENHI-PROJECT-17K19496
[Journal Article] 多色深部イメージングを利用した空間分布制御型ナノDDSの開発2020
- Author(s)
  川上　茂、菅　忠明
- Journal Title
  
  薬学雑誌
  
  Volume: 140
- NAID
  130007838710
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03535
[Journal Article] Synthesis of a high functionality and quality lipid with gp130 binding hydrophobic peptide for the preparation of human glioma cell-targeted PEGylated liposomes2019
- Author(s)
  Suga Tadaharu、Watanabe Masanori、Sugimoto Yuri、Masuda Tomonari、Kuroda Naotaka、Hagimori Masayori、Kawakami Shigeru
- Journal Title
  
  Journal of Drug Delivery Science and Technology
  
  Volume: 49 Pages: 668-673
- DOI
  10.1016/j.jddst.2018.12.037
- NAID
  120006987847
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03535
[Journal Article] 組織吸引デバイスによる生体組織変形をトリガーとする臓器への遺伝子導入技術2019
- Author(s)
  清水一憲、川上茂
- Journal Title
  
  化学工業
  
  Volume: 83(7) Pages: 402-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19496
[Journal Article] Application of direct sonoporation from a defined surface area of the peritoneum: evaluation of transfection characteristics in mice2019
- Author(s)
  Koyo Nishimura, Keita Yonezawa, Shintaro Fumoto, Yusuke Miura, Masayori Hagimori, Koyo Nishida, and Shigeru Kawakam
- Journal Title
  
  Pharmaceutics
  
  Volume: 11(5) Issue: 5 Pages: 244-244
- DOI
  10.3390/pharmaceutics11050244
- NAID
  120006988434
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03535
[Journal Article] Determining transgene expression characteristics using a suction device with multiple hole adjusting a left lateral lobe of the mouse liver2018
- Author(s)
  Haraguchi A, Fuchigami Y, Kawaguchi M, Fumoto S, Ohyama K, Shimizu K, Hagimori M, Kawakami S
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41
- NAID
  130007382692
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19496
[Journal Article] Investigation of Intracellular Delivery of NuBCP-9 by Conjugation with Oligoarginines Peptides in MDA-MB-231 Cells2018
- Author(s)
  Wang Wei、Suga Tadaharu、Hagimori Masayori、Kuroda Naotaka、Fuchigami Yuki、Kawakami Shigeru
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 9 Pages: 1448-1455
- DOI
  10.1248/bpb.b18-00335
- NAID
  130007480022
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2018-09-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03535
[Journal Article] Synthesis of high functionality and quality mannose-grafted lipids to produce macrophage-targeted liposomes2018
- Author(s)
  Hagimori Masayori、Chinda Yorinao、Suga Tadaharu、Yamanami Kazuto、Kato Naoya、Inamine Tatsuo、Fuchigami Yuki、Kawakami Shigeru
- Journal Title
  
  European Journal of Pharmaceutical Sciences
  
  Volume: 123 Pages: 153-161
- DOI
  10.1016/j.ejps.2018.07.036
- NAID
  120006987986
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03535
[Journal Article] Gene delivery system of pDNA using the blood glycoprotein fetuin.2018
- Author(s)
  Kodama Y, Hanamura H, Muro T, Nakagawa H, Kurosaki T, Nakamura T, Kitahara T, Kawakami S, Nakashima M, Sasaki H.
- Journal Title
  
  Journal of Drug Targeting
  
  Volume: 印刷中 Issue: 7 Pages: 604-609
- DOI
  10.1080/1061186x.2017.1405425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08449, KAKENHI-PROJECT-18H02589
[Journal Article] Development of High-Functionality and -Quality Lipids with RGD Peptide Ligands: Application for PEGylated Liposomes and Analysis of Intratumoral Distribution in a Murine Colon Cancer Model2018
- Author(s)
  Suga Tadaharu、Kato Naoya、Hagimori Masayori、Fuchigami Yuki、Kuroda Naotaka、Kodama Yukinobu、Sasaki Hitoshi、Kawakami Shigeru
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 15 Issue: 10 Pages: 4481-4490
- DOI
  10.1021/acs.molpharmaceut.8b00476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03535
[Journal Article] Peptide-Based Cancer-Targeted DDS and Molecular Imaging2017
- Author(s)
  Masayori Hagimori, Yuki Fuchigami, Shigeru Kawakami
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 65 Issue: 7 Pages: 618-624
- DOI
  10.1248/cpb.c17-00098
- NAID
  130006772506
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10366
[Journal Article] Foreword2017
- Author(s)
  Kawakami S
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 65 Issue: 7 Pages: 611-611
- DOI
  10.1248/cpb.c17-ctf6507
- NAID
  130006772513
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19496
[Journal Article] ptimization of renal transfection using a renal suction-mediated transfection method in mice2016
- Author(s)
  Y. Taniguchi, S. Kawakami, Y. Fuchigami, N. Oyama, F. Yamashita, S. Konishi, K. Shimizu, M. Hashida
- Journal Title
  
  Journal of Drug Targeting
  
  Volume: 24 Issue: 5 Pages: 450-456
- DOI
  10.3109/1061186x.2015.1087526
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670082
[Journal Article] Long-term in vivo gene expression in mouse kidney using phiC31 integrase and electroporation2015
- Author(s)
  Y. Otani, S. Kawakami, H. Mukai, Y. Fuchigami, F. Yamashita, and M. Hashida
- Journal Title
  
  Journal of Drug Targeting
  
  Volume: - Issue: 5 Pages: 427-435
- DOI
  10.3109/1061186x.2014.1002788
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670082
[Journal Article] 医薬工連携型DDSの開発2014
- Author(s)
  川上茂、渕上由貴
- Journal Title
  
  医薬ジャーナル
  
  Volume: 50 Pages: 103-107
- Data Source
  KAKENHI-PROJECT-26670082
[Journal Article] Evaluation of inflammatory responses due to siRNA transfer using unmodified and mannose-modified bubble lipoplexes with ultrasound exposure in primary cultured macrophages2014
- Author(s)
  M. Yoshida, S. Kawakami, K. Un, Y. Kono, Y. Higuchi, F. Yamashita, M. Hashida
- Journal Title
  
  Journal of Drug Targeting
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689003
[Journal Article] In vitro evaluation of inhibitory effects of NF-κB activity by small interfering RNA on pro-tumor characteristics of M2-like macrophages2014
- Author(s)
  Y. Kono, S. Kawakami, Y. Higuchi, F. Yamashita, M. Hashida
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 (1) Pages: 137-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689003
[Journal Article] Development of anionic bubble lipopolyplexes for efficient and safe gene transfection with ultrasound exposure in mice2014
- Author(s)
  T. Kurosaki, S. Kawakami, Y. Higuchi, R. Suzuki, K. Maruyama, H. Sasaki, F. Yamashita, M. Hashida
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 176 Pages: 24-34
- NAID
  120006986739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689003
[Journal Article] Inhibition of Cancer Cell Growth by GRP78 siRNA Lipoplex <i>via</i> Activation of Unfolded Protein Response2014
- Author(s)
  K. Matsumura, C. Sakai, S. Kawakami, F. Yamashita, M. Hashida
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 4 Pages: 648-653
- DOI
  10.1248/bpb.b13-00930
- NAID
  130003390969
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240072
[Journal Article] Enhancement of the anti-tumor effect of DNA vaccination using an ultrasound-responsive mannose-modified gene carrier in combination with doxorubicin-encapsulated PEGylated liposomes2014
- Author(s)
  M. Yoshida, S. Kawakami, Y. Kono, K. Un, Y. Higuchi, K. Maruyama, F. Yamashita, and M. Hashida
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 475 Pages: 401-407
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25114705
[Journal Article] Combination of Nanoparticles with Physical Stimuli toward Cancer Therapy2014
- Author(s)
  S. Fumoto, S. Kawakami
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 2 Pages: 212-216
- DOI
  10.1248/bpb.b13-00703
- NAID
  130003390927
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25114705, KAKENHI-PROJECT-25350553
[Journal Article] Kidney-selective gene transfection using anionic bubble lipopolyplexes with renal ultrasound irradiation in mice2014
- Author(s)
  T. Kurosaki, S. Kawakami, Y. Higuchi, R. Suzuki, K. Maruyama, H. Sasaki, F. Yamashita, M. Hashida
- Journal Title
  
  Nanomedicine, Nanotechnology, Biology, and Medicine
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689003
[Journal Article] <i>In Vitro</i> Evaluation of Inhibitory Effect of Nuclear Factor-KappaB Activity by Small Interfering RNA on Pro-tumor Characteristics of M2-Like Macrophages2014
- Author(s)
  Y. Kono, S. Kawakami, Y. Higuchi, F. Yamashita, M. Hashida
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 1 Pages: 137-144
- DOI
  10.1248/bpb.b13-00659
- NAID
  130003382116
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240072, KAKENHI-PROJECT-23689003
[Journal Article] 外部刺激を利用した in vivo 核酸デリバリー法の開発と評価2013
- Author(s)
  川上茂
- Journal Title
  
  薬剤学
  
  Volume: 73 Pages: 153-160
- NAID
  10031171111
- Data Source
  KAKENHI-PROJECT-23689003
[Journal Article] Factors influencing the surface modification of mesenchymal stem cells with fluorescein-pegylated lipids2013
- Author(s)
  Yoshimasa Takafuji, Yuriko Higuchi, Atsushi Muro, Kohei Oshiro, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36(11) Pages: 1731-1738
- NAID
  130003382033
- Data Source
  KAKENHI-PROJECT-24650262
[Journal Article] Factors influencing the surface modification of mesenchymal stem cells with fluorescein-pegylated lipids2013
- Author(s)
  1. Yoshimasa Takafuji, Yuriko Higuchi, Atsushi Muro, Kohei Oshiro, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36 Pages: 1731-1738
- NAID
  130003382033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650262
[Journal Article] 外部刺激を利用したin vivo核酸デリバリー法の開発2013
- Author(s)
  川上茂
- Journal Title
  
  薬剤学
  
  Volume: 73 Pages: 153-160
- Data Source
  KAKENHI-PROJECT-23689003
[Journal Article] Novel ultrasound-responsive gene carrier with ternary structure2012
- Author(s)
  T. Kurosaki, S. Kawakami, R. Suzuki, K. Maruyama, H. Sasaki and M. Hashida
- Journal Title
  
  Human Gene Therapy
  
  Volume: 23
- Data Source
  KAKENHI-PROJECT-23689003
[Journal Article] Enhancement of gene expression by transcriptional activation using doxorubicin-loaded liposome/pDNA complexes2012
- Author(s)
  K. Un, Y. Kono, M. Yoshida, F. Yamashita, S. Kawakami, M. Hashida
- Journal Title
  
  Pharmazie
  
  Volume: 67(5) Pages: 400-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689003
[Journal Article] Efficient suppression of ICAM-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation2012
- Author(s)
  K. Un, S. Kawakami, M. Yoshida, Y. Higuchi, R. Suzuki, K. Maruyama, F. Yamashita M. Hashida
- Journal Title
  
  Hepatology
  
  Volume: 56 (1) Pages: 259-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689003
[Journal Article] Enhancement of gene expression by transcriptional activation using doxorubicin-loaded liposome/pDNA complexes2012
- Author(s)
  K. Un, Y. Kono, F. Yamashita, S. Kawakami, M.Hashida
- Journal Title
  
  Pharmazie
  
  Volume: 67(5) Pages: 400-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240072
[Journal Article] Enhancement of gene expression by transcriptional activation using doxorubicin-loaded liposome/pDNA complexes2012
- Author(s)
  K.Un, Y.Kono, M.Yoshida, F.Yamashita, S.Kawakami, M.Hashida
- Journal Title
  
  Pharmazie
  
  Volume: 5(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689003
[Journal Article] Novel ultrasound-responsive gene carrier with ternary structure2012
- Author(s)
  T. Kurosaki, S. Kawakami, R. Suzuki, K. Maruyama, H. Sasaki, M. Hashida
- Journal Title
  
  Human Gene Therapy
  
  Volume: 23 (10)
- Data Source
  KAKENHI-PROJECT-23689003
[Journal Article] Evaluation of long-term gene expression in mouse liver using phiC31 integrase and hydrodynamic injection2012
- Author(s)
  Y.Umemoto, S.Kawakami, Y.Otani, Y.Higuchi, F.Yamashita, M.Hashida
- Journal Title
  
  Biological and Pharmaceutial Bulletin
  
  Volume: (印刷中)
- NAID
  130001872117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659110
[Journal Article] The involvement of NK cell activation following intranasal administration of CpG DNA lipoplex in the prevention of pulmonary metastasis and peritoneal dissemination in mice2012
- Author(s)
  Shuwen Zhou・Shigeru Kawakami・Yuriko Higuchi・Fumiyoshi Yamashita・Mitsuru Hashida
- Journal Title
  
  Clinical and Experimental metastasis
  
  Volume: 29 Issue: 1 Pages: 63-70
- DOI
  10.1007/s10585-011-9429-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J02743, KAKENHI-PROJECT-23240072
[Journal Article] 糖修飾超音波応答性リポソームによるがん免疫治療・抗炎症治療戦略2012
- Author(s)
  運敬太、川上茂、橋田充
- Journal Title
  
  実験医学増刊
  
  Volume: 30 Pages: 135-141
- Data Source
  KAKENHI-PROJECT-23689003
[Journal Article] Suppression of melanoma growth and metastasis by DNA vaccination using an ultrasound-responsive and mannose-modified gene carrier2011
- Author(s)
  Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M
- Journal Title
  
  Mol Pharm 8(2)
  
  Pages: 543-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Suppression of melanoma growth and metastasis by DNA vaccination using an ultrasound-responsive and mannose-modified gene carrier2011
- Author(s)
  K.Un, S.Kawakami, R.Suzuki, K.Maruyama, F.Yamashita, M.Hashida
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 8(2) Pages: 543-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Involvement of activated transcriptional process in the efficient gene transfection using unmodified and mannose-modified bubble lipoplexes with ultrasound exposure2011
- Author(s)
  K. Un, S. Kawakami, Y. Higuchi, R. Suzuki, K. Maruyama, F. Yamashita, M. Hashida
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 156 (3) Pages: 355-363
- NAID
  120003644378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689003
[Journal Article] The elucidation of gene transferring mechanism by ultrasound-responsive unmodified and mannose-modified lipoplexes2011
- Author(s)
  Un K, Kawakami S, Yoshida M, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M
- Journal Title
  
  Biomaterials 32(20)
  
  Pages: 4659-4669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Intranasal administration of CpG DNA lipoplex prevents pulmonary metastasis in mice2010
- Author(s)
  Zhou S, Kawakami S, Yamashita F, Hashida M
- Journal Title
  
  Cancer Lett. 287(1)
  
  Pages: 75-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Key Physiological Phenomena Governing Transgene Expression Based on Tissue Pressure-Mediated Transfection in Mice2010
- Author(s)
  Hidefumi Mukai, Shigeru Kawakami, Haruyuki Takahashi, Yuki Otani, Kyosuke Satake, Fumiyoshi Yamashita, and Mitsuru Hashida
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 33 Issue: 9 Pages: 1627-1632
- DOI
  10.1248/bpb.33.1627
- NAID
  130000322368
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659110
[Journal Article] Intranasal administration of CpG DNA lipoplex prevents pulmonary metastasis in mice2010
- Author(s)
  Zhou S, Kawakami S, Yamashita F, Hashida M
- Journal Title
  
  Cancer Lett 287(1)
  
  Pages: 75-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Development of an ultrasound-responsive and mannose-modified gene carrier for DNA vaccine therapy2010
- Author(s)
  Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M
- Journal Title
  
  Biomaterials 31(30)
  
  Pages: 7813-7826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Enhanced transfection efficiency into macrophages and dendritic cells by a combination method using mannosylated lipoplexes and bubble liposomes with ultrasound exposure2010
- Author(s)
  K.Un, S.Kawakami, R.Suzuki, K.Maruyama, F.Yamashita, M.Hashida
- Journal Title
  
  Human Gene Therapy
  
  Volume: 21(1) Pages: 65-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Intranasal administration of CpG DNA lipoplex prevents pulmonary metastasis in mice.2010
- Author(s)
  S. Zhou, S. Kawakami, F. Yamashita, M. Hashida
- Journal Title
  
  Cancer Letters 287(1)
  
  Pages: 75-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016035
[Journal Article] Intranasal administration of CpG DNA lipoplex prevents pulmonary metastasis in mice2010
- Author(s)
  S.Zhou, S.Kawakami, F.Yamashita, M.Hashida
- Journal Title
  
  Cancer Letters
  
  Volume: 287(1) Pages: 75-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Gamma-polyglutamic acid-coated vectors for effective and safe gene therapy2010
- Author(s)
  Kurosaki T, Kitahara T, Kawakami S, Higuchi Y, Yamaguchi A, Nakagawa H, Kodama Y, Hamamoto T, Hashida M, Sasaki H
- Journal Title
  
  J Control Release
  
  Volume: 142(3) Pages: 404-410
- NAID
  120006984597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Gamma-polyglutamic acid-coated vectors for effective and safe gene therapy.2010
- Author(s)
  Kurosaki T, Kitahara T, Kawakami S, Higuchi Y, Yamaguchi A, Nakagawa H, Kodama Y, Hamamoto T, Hashida M, Sasaki H.
- Journal Title
  
  J Control Release.
  
  Volume: 142 Pages: 404-410
- NAID
  120006984597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Key physiological phenomena governing transgene expression based on tissue pressure-mediated transfection in mice2010
- Author(s)
  H.Mukai, S.Kawakami, H.Takahashi, Y.Otani, K.Satake, F.Yamashita, M.Hashida
- Journal Title
  
  Biological & Pharmaceutical Bulletin
  
  Volume: 33(9) Pages: 1627-1637
- NAID
  130000322368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659110
[Journal Article] Enhanced transfection efficiency into macrophages and dendritic cells by a combination method using mannosylated lipoplexes and bubble liposomes with ultrasound exposure2010
- Author(s)
  Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M
- Journal Title
  
  Hum Gene Ther 21(1)
  
  Pages: 65-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Development of an ultrasound-responsive and mannose-modified gene carrier for DNA vaccine therapy2010
- Author(s)
  K.Un, S.Kawakami, R.Suzuki, K.Maruyama, F.Yamashita, M.Hashida
- Journal Title
  
  Biomaterials
  
  Volume: 31(30) Pages: 7813-7826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] The development of a gene vector electrostatically assembled with a polysaccharide capsule.2009
- Author(s)
  Kurosaki, T, Kitahara, T., Kawakami, S., Nishida, K., Nakamura, J., Teshima, M., Nakagawa, H., Kodama, Y., To, H., Sasaki, H.
- Journal Title
  
  Biomaterials 30
  
  Pages: 4427-4434
- NAID
  120006984133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Mannosylated cationic liposomes/CpG DNA complex for the treatment of hepatic metastasis after intravenous administration in mice2009
- Author(s)
  Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M
- Journal Title
  
  J Pharm Sci 98(3)
  
  Pages: 1193-1197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Immunostimulatory Characteristics Induced by LinearPolyethyleneimine/plasmid DNA Complexes in Cultured Macrophages2009
- Author(s)
  Yasunori Saito, Yuriko Higuchi, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida
- Journal Title
  
  Human Gene Therapy 20(2)
  
  Pages: 137-145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209006
[Journal Article] Enhanced in vivo antitumor efficacy of fenretinide encapsulated in polymeric micelles.2009
- Author(s)
  T. Okuda, S. Kawakami, Y. Higuchi, Y. Oka, T. Satoh, M. Yokoyama, F. Yamashita, M. Hashida
- Journal Title
  
  International Journal of Pharmaceutics 373(1-2)
  
  Pages: 100-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016035
[Journal Article] The development of a gene vector electrostatically assembled with a polysaccharide capsule2009
- Author(s)
  Kurosaki T, Kitahara T, Kawakami S, Nishida K, Nakamura J, Teshima M, Nakagawa H, Kodama Y, To H, Sasaki H
- Journal Title
  
  Biomaterials
  
  Volume: 30(26) Pages: 4427-4434
- NAID
  120006984133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390010
[Journal Article] Non-viral approaches for targeted delivery of plasmid DNA and oligonucleotide2008
- Author(s)
  Kawakami S, Higuchi Y, Hashida M
- Journal Title
  
  J Pharm Sci 97(2)
  
  Pages: 726-745
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Anti-tumor effect of all-trans retinoic acid loaded polymeric micelles in solid tumor bearing mice.2008
- Author(s)
  N. Chansri, S. Kawakami, M. Yokoyama, T. Yamamoto, P. Charoensit, M. Hashida
- Journal Title
  
  Pharmaceutical Research 25(2)
  
  Pages: 428-434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016035
[Journal Article] Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG2008
- Author(s)
  Y. Kuramoto, S. Kawakami, S. Zhou, K. Fukuda, F. Yamashita, M.
- Journal Title
  
  Journal of Controlled Release 126
  
  Pages: 274-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Use of mannosylated cationic liposomes/ immunostimulatory CpG DNA complex for effective inhibition of peritoneal dissemination in mice2008
- Author(s)
  Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M
- Journal Title
  
  J Gene Med 10(4)
  
  Pages: 392-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mic2008
- Author(s)
  Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M
- Journal Title
  
  J Control Release 126(3)
  
  Pages: 274-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Renal press-mediatedtransfection method for plasmid DNAand siRNA to the kidney2008
- Author(s)
  Hidefumi Mukai, Shigeru Kawakami, Mitsuru Hashida
- Journal Title
  
  Biochemical and Biophysical Research Communications 372(3)
  
  Pages: 383-387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209006
[Journal Article] Mannosylated semiconductor quantum dots for the labeling of macrophage.2008
- Author(s)
  Y. Higuchi, M. Oka, S. Kawakami, M. Hashida
- Journal Title
  
  Journal of Controlled Release 125(2)
  
  Pages: 131-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016035
[Journal Article] Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mice2008
- Author(s)
  Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M
- Journal Title
  
  J Control Release 126(3)
  
  Pages: 274-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Block copolymer design for stable encapsulation of N-(4-hydroxyphenyl)retinamide into polymeric micelles in mice.2008
- Author(s)
  T. Okuda, S. Kawakami, M. Yokoyama, T. Yamamoto, F. Yamashita, M. Hashida
- Journal Title
  
  International Journal of Pharmaceutics 357
  
  Pages: 318-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016035
[Journal Article] Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats2008
- Author(s)
  Wijagkanalan W, Kawakami S, Takenaga M, Igarashi R, Yamashita F, Hashida M
- Journal Title
  
  J Control Release 125(2)
  
  Pages: 121-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Hepatocyte-selective gene transfer by galactosylated protein/linear polyethylenimine/plasmid DNA complexes in mice2007
- Author(s)
  Miyuki Hohokabe, Yuriko Higuchi, Hidefumi Mukai, Shigeru Kawakami, Mitsuru Hashida
- Journal Title
  
  Journal of Biome dical Nanotechnology 3(3)
  
  Pages: 277-284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209006
[Journal Article] Development of an antigen presenting cell-targeted DNA vaccine against melanoma by mannosylated liposomes2007
- Author(s)
  Y. Lu, S. Kawakami, F. Yamashita, M. Hashida
- Journal Title
  
  Biomaterials 28
  
  Pages: 3255-3262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Development of an antigen presenting cell-targeted DNA vaccine against melanoma by mannosyated liposomes2007
- Author(s)
  Lu Y, Kawakami S, Yamashita F, Hashida M
- Journal Title
  
  Biomaterials 28(21)
  
  Pages: 255-3262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationicliposomes in mice2007
- Author(s)
  Ayumi Sato, Motoki Takagi, Akira Shimamoto, Shigeru Kawakami, Mitsuru Hashida
- Journal Title
  
  Biomaterials 28(7)
  
  Pages: 1434-1442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209006
[Journal Article] Optimization of tumor-selective targeting by basic fibroblast growth factor-binding peptide grafted2007
- Author(s)
  T. Terada, M. Mizobata, S. Kawakami, F. Yamashita, M.
- Journal Title
  
  Journal of Controlled Release 119
  
  Pages: 262-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689005
[Journal Article] The potential role of fucosylated cationic liposome/NFkB decoy complexesin the treatment of cytokine-related liver disease2007
- Author(s)
  Yuriko Higuchi, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida
- Journal Title
  
  Biomaterials 28(3)
  
  Pages: 532-539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209006
[Journal Article] Efficient protection by cationizedcatalase against H2O2 injury in primary cultured alveolar epithelial cells2007
- Author(s)
  Takayuki Nemoto, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida
- Journal Title
  
  Journal of Controlled Release 121(1-2)
  
  Pages: 74-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209006
[Journal Article] Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration.2006
- Author(s)
  T. Okuda, S. Kawakami, T. Maeie, T. Niidome, F. Yamashita, M. Hashida
- Journal Title
  
  Journal of Controlled Release 114(1)
  
  Pages: 69-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016035
[Journal Article] Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice2006
- Author(s)
  Shigeru Kawakami et al.
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 317(3)
  
  Pages: 1382-1390
- Data Source
  KAKENHI-PROJECT-18209006
[Journal Article] Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipidconntaining galactosylated liposomes for hepatocellular carcinoma-selec tive targeting2006
- Author(s)
  Takeshi Terada, Mieko Iwai, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida
- Journal Title
  
  Journal of Controlled Release 111(3)
  
  Pages: 333-342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209006
[Journal Article] PEGylated lysine dendrimers for tumor-selective targeting after intravenous injection in tumor-bearing mice.2006
- Author(s)
  T. Okuda, S. Kawakami, N. Akimoto, T. Niidome, F. Yamashita, M. Hashida
- Journal Title
  
  Journal of Controlled Release 116(3)
  
  Pages: 330-336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016035
[Journal Article] Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice2006
- Author(s)
  Shigeru Kawakami et al.
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 317(3)
  
  Pages: 1382-1390
- Data Source
  KAKENHI-PROJECT-17790119
[Journal Article] Inhibition of pulmonary metastasis by all-trans retinoic acid incorporated in cationic liposomes in mice.2006
- Author(s)
  S. Suzuki, S. Kawakami, N. Chansri, F. Yamashita, M. Hashida
- Journal Title
  
  Journal of Controlled Release 116(1)
  
  Pages: 58-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016035
[Journal Article] Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid conntaining galactosylated liposomes for hepatocellular carcinoma-selective targeting.2006
- Author(s)
  T. Terada, M. Iwai, S. Kawakami, F. Yamashita, M. Hashida
- Journal Title
  
  Journal of Controlled Release 111(3)
  
  Pages: 333-342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016035
[Journal Article] Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice2006
- Author(s)
  Shigeru Kawakami, Yoshitaka Ito, Pensri Charoensit, Fumiyoshi Yamashita,Mitsuru Hashida
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 317(3)
  
  Pages: 1382-1390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209006
[Journal Article] Interaction with blood components plays a crucial role in asialoglycoprotein receptor-mediated in vivo gene transfer by galactosylated lipoplex.2005
- Author(s)
  S. Fumoto, S. Kawakami, K. Shigeta, Y. Higuchi, F. Yamashita, M. Hashida
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 315(2)
  
  Pages: 484-493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016035
[Journal Article] Biodistribution characteristics of all-trans retinoic acid incorporated in liposomes and polymeric micelles following intravenous administration.2005
- Author(s)
  S. Kawakami, P. Opanasopit, M. Yokoyama, N. Chansri, T. Yamamoto, T. Okano, F. Yamashita, M. Hashida
- Journal Title
  
  Journal of Pharmaceutical Sciences 94(2)
  
  Pages: 2606-2615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016035
[Journal Article] Biodistribution characteristics of all-trans retinoic acid incorporated in liposomes and polymeric micelles following intravenous administration2005
- Author(s)
  S.Kawakami et al.
- Journal Title
  
  Journal of Pharmaceutical Sciences 94(12)
  
  Pages: 2606-2615
- Data Source
  KAKENHI-PROJECT-17016035
[Journal Article] Uptake characteristics of galactosylated emulsion by HepG2 hepatoma cells2005
- Author(s)
  Managit C, Kawakami S, Yamashita F, Hashida M.
- Journal Title
  
  Int.J.Pharm. 301(1-2)
  
  Pages: 255-261
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209006
[Journal Article] Enhanced gene expression in lung by a stabilized lipoplex using sodium chloride for complex formation2005
- Author(s)
  Shigeru Kawakami et al.
- Journal Title
  
  Journal of Gene Medicine 7(12)
  
  Pages: 1526-1533
- Data Source
  KAKENHI-PROJECT-17790119
[Journal Article] Enhanced hepatocyte-selective in vivo gene expression by stabilized galactosylated liposome/plasmid DNA complex using sodium chloride for complex formation2004
- Author(s)
  Fumoto S, Kawakami S, Ito Y, Shigeta K, Yamashita F, Hashida M.
- Journal Title
  
  Mol.Ther. 10(4)
  
  Pages: 719-729
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209006
[Journal Article] Enhancement of immune responses by DNA vaccination through targeted gene delivery using mannosylated cationic liposome formulations following intravenous administration in mice2004
- Author(s)
  Hattori Y, Kawakami S, Suzuki S, Yamashita F, Hashida M.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 317(4)
  
  Pages: 992-999
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209006
[Journal Article] Effect of cationic charge on receptor-mediated transfection using mannosylated cationic liposome/plasmid DNA complexes following the intravenous administration in mice2004
- Author(s)
  Shigeru Kawakami et al.
- Journal Title
  
  Pharmazie 59(5)
  
  Pages: 405-408
- Data Source
  KAKENHI-PROJECT-15790095
[Journal Article] Glycosylated cationic liposomes for carbohydrate receptor-mediated gene transfer2003
- Author(s)
  Nishikawa M, Kawakami S, Yamashita F, Hashida M.
- Journal Title
  
  Methods Enzymol. 373
  
  Pages: 384-399
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209006
[Journal Article] Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver2003
- Author(s)
  Morimoto K, Nishikawa M, Kawakami S, Nakano T, Hattori Y, Fumoto S, Yamashita F, Hashida M.
- Journal Title
  
  Mol.Ther. 7(2)
  
  Pages: 254-261
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209006
[Journal Article] Analysis of hepatic disposition of native and galactosylated polyethylenimine complexed with plasmid DNA in perfused rat liver2003
- Author(s)
  Fumoto S, Kawakami S, Ishizuka M, Nishikawa M, Yamashita F, Hashida M.
- Journal Title
  
  Drug Metab.Pharmacokinet. 18(4)
  
  Pages: 230-237
- NAID
  10012458871
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209006
[Journal Article] Analysis of hepatic disposition of galactosylated cationic liposome/plasmid DNA complexes in perfused rat liver2003
- Author(s)
  Fumoto S, Nakadori F, Kawakami S, Nishikawa M, Yamashita F, Hashida M.
- Journal Title
  
  Pharm.Res. 20(9)
  
  Pages: 1452-1459
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209006
[Journal Article] Evaluation of long-term gene expression in mouse liver using phiC31 integrase and hydrodynamic injection
- Author(s)
  Yoshiaki Umemoto, Shigeru Kawakami, Yuki Otani, Yuriko Higuchi, Fumiyoshi Yamashita, and Mitsuru Hashida
- Journal Title
  
  Biological & Pharmaceutical Bulletin
  
  Volume: (in press)
- NAID
  130001872117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659110
[Patent] 生体由来材料の透明化試薬2022
- Inventor(s)
  麓伸太郎, 川上茂, 西田孝洋
- Industrial Property Rights Holder
  麓伸太郎, 川上茂, 西田孝洋
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Acquisition Date
  2022
- Data Source
  KAKENHI-PROJECT-18H03535
[Patent] 脂質性化合物、リポソーム、エクソソーム、脂質ナノ粒子及びドラッグデリバリーシステム2022
- Inventor(s)
  川上茂, 向井英史, 杉本友里, 海野水綺, 神谷万里子
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-21H03818
[Patent] 脂質性化合物、リポソーム、エクソソーム、脂質ナノ粒子及びドラッグデリバリーシステム2021
- Inventor(s)
  川上茂, 向井英史, 杉本友里, 海野水綺
- Industrial Property Rights Holder
  川上茂, 向井英史, 杉本友里, 海野水綺
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-190933
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-18H03535
[Patent] 肺指向性薬物送達体2019
- Inventor(s)
  佐々木均、兒玉幸修、川上茂
- Industrial Property Rights Holder
  佐々木均、兒玉幸修、川上茂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-098677
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18H02589
[Patent] 経肺投与用薬物送達体2019
- Inventor(s)
  佐々木均、兒玉幸修、川上茂
- Industrial Property Rights Holder
  佐々木均、兒玉幸修、川上茂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-099112
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18H02589
[Patent] 生体由来材料の透明化用試薬2018
- Inventor(s)
  麓伸太郎、川上茂、西田孝洋
- Industrial Property Rights Holder
  麓伸太郎、川上茂、西田孝洋
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-17K19496
[Patent] アニオン性を有する新規ナノバブルポリ－リポ・プレックスの製造方法2012
- Inventor(s)
  黒崎友亮、川上　茂、橋田　充
- Industrial Property Rights Holder
  京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-018409
- Filing Date
  2012-08-20
- Data Source
  KAKENHI-PROJECT-23689003
[Patent] 導入対象物質の送達装置の作動方法および導入対象物質の送達方法2010
- Inventor(s)
  清水一憲、小西聡、川上茂、橋田充
- Industrial Property Rights Holder
  京都大学、立命館大学
- Industrial Property Number
  2010-238885
- Filing Date
  2010-10-25
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] 超音波照射とマイクロバブルを利用した脳内へのmRNA封入脂質ナノ粒子の送達2024
- Author(s)
  川上茂
- Organizer
  第129回日本解剖学会総会・全国学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K17479
[Presentation] 超音波照射とマイクロバブルを利用した脳内へのmRNA封入脂質ナノ粒子の送達2024
- Author(s)
  川上茂
- Organizer
  第129回日本解剖学会総会・全国学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] 脂質ナノ粒子の高機能化を目的としたポリペプチドの開発と核酸・細胞医薬創出への展開2024
- Author(s)
  川上茂
- Organizer
  高度な基礎力と研究マインドを持った先導的薬剤師育成事業、SDGs推進に係る連携創出の場形成支援事業合同シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] ナノ粒子を用いた核酸医薬の標的指向化技術の開発に関する研究2023
- Author(s)
  川上茂
- Organizer
  第20回技術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] Development of Ligand Modified Nanoparticles for Targeted Drug Delivery of Nucleic Acid2023
- Author(s)
  Shigeru Kawakami
- Organizer
  7th Gratama Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] Fc領域結合ペプチド修飾脂質の設計・合成と抗体修飾脂質ナノ粒子の開発2023
- Author(s)
  松本眞, 松尾彩香, 森谷成美, 加藤直也, 神谷万里子, 吉田道春, 日宇健, 松尾孝之, 川上茂
- Organizer
  第66回日本脳循環代謝学会
- Data Source
  KAKENHI-PROJECT-23K08503
[Presentation] Ifluence of lipid composition of messenger RNA-loaded lipid nanoparticles on the protein expression via intratracheal administration in mice2023
- Author(s)
  Geng Longjian, Makoto Matsumoto, Mizuki Umino, Mariko Kamiya, Hidefumi Mukai, Shigeru Kawakami
- Organizer
  第28回創剤フォーラム若手研究会
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] Fc領域結合ペプチド修飾脂質の設計・合成と抗体修飾脂質ナノ粒子の開発2023
- Author(s)
  松本眞, 松尾彩香, 森谷成美, 加藤直也, 神谷万里子, 吉田道春, 日宇健, 松尾孝之, 川上茂
- Organizer
  第66回日本脳循環代謝学会
- Data Source
  KAKENHI-PROJECT-23K17479
[Presentation] 脂質ナノ粒子の標的指向型製剤の設計と評価2023
- Author(s)
  川上茂
- Organizer
  日本薬学会第143年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] mRNA 封入脂質ナノ粒子における KK ペプチド脂質の修飾量が物理化学的性質および肺における発現に及ぼす影響2023
- Author(s)
  大貝洋一郎, Geng Longjian, Yao Feijie, 神谷万里子, 向井英史, 川上茂
- Organizer
  日本バイオマテリアル学会2023年度九州ブロック研究発表会
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] Development of local expression mRNA-loaded lipid nanoparticles based on a modification of novel peptide lipids2023
- Author(s)
  Mariko Kamiya, Makoto Matsumoto, Mizuki Umino, Hidefumi Mukai, Shigeru Kawakami
- Organizer
  2023 ICCP450/JSSX International Joint Meeting in Shizuoka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] 配向性を制御した高品質な抗体修飾mRNA封入脂質ナノ粒子の開発2023
- Author(s)
  松本眞, ナジー美緒, 高島由季, 神谷万里子, 向井英史, 川上茂
- Organizer
  第40回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-23K17479
[Presentation] 脂質ナノ粒子製剤を対象としたアクティブターゲティング技術の開発2023
- Author(s)
  川上茂
- Organizer
  日本薬剤学会第38年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] In vivo での投与部位選択的高発現を目指した KK 脂質修飾 mRNA 封入脂質ナノ粒子の開発2023
- Author(s)
  神谷万里子, 向井英史, 川上茂
- Organizer
  遺伝子・デリバリー研究会第 22 回シンポジウム
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] 標的指向DDS開発と組織透明化評価2022
- Author(s)
  川上茂
- Organizer
  創剤研究コンソーシアム 2021年度第2回研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] mRNA封入脂質ナノ粒子の安定性、物理化学的性質、タンパク質発現の相関の評価2022
- Author(s)
  神谷万里子, 松本眞, 川口真帆, 水上修作, 向井英史, 川上茂
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] 標的指向DDS開発と組織透明化評価2022
- Author(s)
  川上茂
- Organizer
  創剤研究コンソーシアム 2021年度第2回研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] mRNA封入脂質ナノ粒子の保存条件が物理化学的性質および発現に及ぼす影響2022
- Author(s)
  神谷万里子, 松本眞, 泉龍昇, 三浦樹幸, 向井英史, 川上茂
- Organizer
  日本核酸医薬学会第7回年会
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] エレクトロポレーション法およびLNPを用いた樹状細胞への遺伝子およびmRNA導入法による発現特性ならびに抗原提示能の比較2022
- Author(s)
  神谷万里子, 実政澪, 仙波紗英, 山下和真, 松本眞, 泉龍昇, 三浦樹幸, 鶴丸雅子, 向井英史, 川上茂
- Organizer
  遺伝子・デリバリー研究会第21回シンポジウム
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] 筋肉内投与における脂質ナノ粒子コレステロール含有量のタンパク発現分布への影響2022
- Author(s)
  川口真帆, 小野亜佳莉, 神谷万里子, 水上修作, 向井英史, 川上茂
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] 遺伝子導入技術2022
- Author(s)
  川上茂
- Organizer
  第38回日本DDS学会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] 核酸・mRNA医薬品ナノ粒子製剤の動態評価手法2021
- Author(s)
  向井英史, 川上茂
- Organizer
  日本薬物動態学会第36年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] がん組織における間質・血管・DDSキャリアの新規多色深部イメージング法の開発2021
- Author(s)
  増田智成, 菅忠明, 向井英史, 川上茂
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 脳を標的としたリポソーム・脂質ナノ粒子のDDS技術の開発2021
- Author(s)
  川上茂
- Organizer
  日本薬剤学会第36年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] がん組織における間質・血管・DDSキャリアの新規多色深部イメージング法の開発2021
- Author(s)
  増田智成, 実政澪, 松本眞, 向井英史, 川上茂
- Organizer
  日本核酸医薬学会第6回年会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 脳を標的としたリポソーム・脂質ナノ粒子のDDS技術の開発2021
- Author(s)
  川上茂
- Organizer
  日本薬剤学会第36年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] Luciferase mRNA封入脂質ナノ粒子の保存安定性に関する研究2021
- Author(s)
  神谷万里子, 川口真帆, 小野亜佳莉, 鶴丸雅子, 水上修作, 向井英史, 川上茂
- Organizer
  日本薬剤学会第2回超分子薬剤学FGシンポジウム
- Data Source
  KAKENHI-PROJECT-21H03818
[Presentation] がん標的指向性DDSキャリアの実用化を目的とした環状ペプチドをリガンドとする高機能・高品質脂質の開発2020
- Author(s)
  佐藤匠、渕上由貴、菅忠明、加藤直也、萩森政頼、川上茂
- Organizer
  日本バイオマテリアル学会九州ブロック第9回講演会
- Data Source
  KAKENHI-PROJECT-17K10366
[Presentation] 環状RGDペプチドをリガンドとする高機能・高品質脂質の合成法の開発と環状RGD修飾リポソームの細胞取り込み特性の評価2019
- Author(s)
  佐藤匠、菅忠明、加藤直也、渕上由貴、萩森政頼、川上茂
- Organizer
  第36回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17K10366
[Presentation] ：Suppression effect on peritoneal fibrosis by HGF gene encoding CpG-free plasmid DNA using nanobubbles with ultrasound irradiation2019
- Author(s)
  Koyo Nishimura, Maho Kawaguchi, Shintaro Fumoto, Shigeru Kawakami
- Organizer
  19th Symposium for Gene, Design and Delivery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 腎臓への圧力刺激を利用した遺伝子導入法：輸尿管投与・腎動脈投与後の腎臓内遺伝子発現と空間分布特性の解明2019
- Author(s)
  大山奈津子、川口真帆、鶴丸雅子、萩森政頼、川上茂
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K19496
[Presentation] 膵臓癌細胞を標的としたHER2指向型KCC修飾エクソソーム製剤の開発2019
- Author(s)
  杉本友里、菅忠明、野田健太、山吉麻子、麓伸太郎、川上茂
- Organizer
  日本核酸医薬学会第5回年会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 腹膜線維症病態時の組織構造と遺伝子発現分布の組織内空間的評価による腹腔内組織への超音波応答性DDSの開発2019
- Author(s)
  西村光洋、小川昂輝、麓伸太郎、川上　茂
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 膵癌深部への送達を目的とする微小な膵癌指向型リポソーム製剤の開発2019
- Author(s)
  菅忠明、内山詩乃、増田智成、萩森政頼、川上茂
- Organizer
  日本薬学会139年会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 組織内動態および分布解析に基づく標的指向型DDSの開発戦略2019
- Author(s)
  菅忠明、小川昂輝、西村光洋、大山奈津子、加藤直也、増田智成、川上茂
- Organizer
  長崎障害者支援再生医療研究会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 多色深部イメージングを利用した空間分布制御型ナノDDSの開発2019
- Author(s)
  川上茂、菅忠明
- Organizer
  日本薬学会第139年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19496
[Presentation] 静電的相互作用を基盤としたaptamer被膜型遺伝子ベクターの開発2019
- Author(s)
  黒崎友亮、兒玉幸修、中川博雄、中村忠博、大山要、中嶋幹郎、川上茂、佐々木均
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18H02589
[Presentation] リポソームの腫瘍深部送達を目的とする標的指向型Limit Sizeリポソームの開発2019
- Author(s)
  菅忠明、野田健太、杉本友里、増田智成、麓伸太郎、川上茂
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 多色深部イメージングを利用した空間分布制御型ナノDDSの開発2019
- Author(s)
  川上茂、菅忠明
- Organizer
  日本薬学会139年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] Development of ligand-modified liposomes for cancer-targeted delivery system2019
- Author(s)
  Tadaharu Suga and Shigeru Kawakami
- Organizer
  APSTJ Global Education Seminar 2018 3rd
- Invited
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 多色深部イメージングを利用した腹膜組織における遺伝子発現・核酸送達評価法の開発2018
- Author(s)
  西村光洋、萩森政頼、三浦雄介、麓伸太郎、兒玉幸修、佐々木均、川上茂
- Organizer
  第40回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 輸尿管投与による腎臓へのin vivo遺伝子導入における外来遺伝子発現分布の評価2018
- Author(s)
  大山奈津子、川口真帆、高比良慎、鶴丸雅子、萩森政頼、川上茂
- Organizer
  遺伝子・デリバリー研究会第18回夏期セミナー
- Data Source
  KAKENHI-PROJECT-17K19496
[Presentation] 血管ならびに輸尿管経路による腎臓へのin vivo遺伝子導入における外来遺伝子発現分布の評価2018
- Author(s)
  大山奈津子、川口真帆、高比良慎、鶴丸雅子、萩森政頼、橋田充、川上茂
- Organizer
  第24回創剤フォーラム若手研究会
- Data Source
  KAKENHI-PROJECT-17K19496
[Presentation] インテグリンαvβ3を標的とした新規機能性脂質修飾リポソームの開発2018
- Author(s)
  加藤直也、萩森政頼、渕上由貴、川上茂
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10366
[Presentation] 高機能・高品質（HFQ）脂質を用いた標的指向型DDS 製剤の開発2018
- Author(s)
  川上茂、菅忠明
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 超音波応答性ナノバブルを利用した腹腔内組織への遺伝子導入法における遺伝子発現特性評価と腹膜線維症治療への応用2018
- Author(s)
  西村光洋、米澤敬大、渕上由貴、麓　伸太郎、萩森政頼、川上　茂
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 疎水性ペプチドをリガンドとするヒトグリオーマ指向型の高機能・高品質脂質の設計とリポソームへの応用2018
- Author(s)
  菅忠明、渡邊公則、増田智成、黒田直敬、萩森政頼、川上茂
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 超音波応答性ナノバブルを用いた脳室組織への遺伝子導入法における脳室内遺伝子発現分布の評価2018
- Author(s)
  小川昂輝、渕上由貴、萩森政頼、川上茂
- Organizer
  日本超音波医学会第28回九州地方会学術集会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 高機能・高品質脂質によるHER2指向リポソームの開発:膵癌へのDDSキャリアとしての応用2018
- Author(s)
  菅忠明、内山詩乃、三浦雄介、黒田直敬、萩森政頼、川上茂
- Organizer
  第40回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] リポソームの標的指向化を企図した高機能・高品質 (HFQ) 脂質の開発：相異なる物性を示すペプチドをリガンドとするHFQ脂質の設計・評価2018
- Author(s)
  菅忠明、萩森政頼、渡邊公則、増田智成、黒田直敬、川上茂
- Organizer
  遺伝子・デリバリー研究会第18回夏期セミナー
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 高機能・高品質脂質を用いたリポソームならびにエクソソーム製剤の開発と細胞取り込み特性の評価2018
- Author(s)
  杉本友里，菅忠明，曹発健，萩森政頼，山吉麻子，川上茂
- Organizer
  日本バイオマテリアル学会九州ブロック第8回講演会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 難治性癌の組織構造とDDSの空間分布解析を目的とした組織内多色イメージング法の開発2018
- Author(s)
  菅忠明、増田智成、三浦雄介、萩森政頼、川上茂
- Organizer
  第1回超分子薬剤学FGシンポジウム
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] Development of a multi-color deep imaging method for the evaluation of gene delivery system in the kidney2018
- Author(s)
  N. Oyama, M. Kawaguchi, M. Takahira, M. Tsurumaru, M. Hagimori, S. Kawakami
- Organizer
  18th Symposium for Gene, Design and Delivery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19496
[Presentation] KCC修飾リポソームの膵癌指向性の評価と膵癌におけるDDSの空間分布解析のための組織内多色イメージング法の開発2018
- Author(s)
  菅忠明、内山詩乃、増田智成、萩森政頼、麓伸太郎、川上茂
- Organizer
  第35回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 腎臓における外来遺伝子発現・送達の多色深部イメージング2018
- Author(s)
  大山奈津子、川口真帆、高比良慎、鶴丸雅子、萩森政頼、川上茂
- Organizer
  日本核酸医薬学会第4回年会
- Data Source
  KAKENHI-PROJECT-17K19496
[Presentation] 細胞膜透過ペプチドR8を機能性素子とする高機能・高品質脂質の設計とR8修飾リポソームの細胞取り込み特性の評価2018
- Author(s)
  杉本友里、菅忠明、萩森政頼、川上茂
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] Synthesis of high functionality and quality mannose-grafted lipids and its application for macrophage-targeted liposomes2018
- Author(s)
  Masayori Hagimori, Tadaharu Suga, Yorinao Chinda, Kazuto Yamanami, Naoya Kato, Tatsuo Inamine, Yuki Fuchigami, Shigeru Kawakami
- Organizer
  18th Symposium for Gene, Design and Delivery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] Integrin αvβ3指向性ペプチドをリガンドとする高機能・高品質脂質の開発：PEGリポソームへの応用と腫瘍内空間分布の解析2018
- Author(s)
  菅忠明、萩森政頼、黒田直敬、川上茂
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] Synthesis of a RGD modified high functionality and quality lipid for the preparation of RGD-grafted PEGylated liposomes in tumor targeting2018
- Author(s)
  Tadaharu Suga, Masayori Hagimori, Yuri Sugimoto, Naotaka Kuroda, Shigeru Kawakami
- Organizer
  18th Symposium for Gene, Design and Delivery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] インテグリンαvβ3を標的とした新規機能性脂質修飾リポソームの開発2018
- Author(s)
  加藤直也、萩森政頼、菅忠明、川上茂
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03535
[Presentation] 肝臓吸引圧法におけるマウス肝臓内遺伝子発現特性の解明とメカノセンサー分子に関する評価2018
- Author(s)
  原口綾奈、渕上由貴、大山要、清水一憲、麓伸太郎、萩森政頼、川上茂
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17K19496
[Presentation] 医療イノベーションにおけるDDS2017
- Author(s)
  川上茂
- Organizer
  第 41回西日本薬剤学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19496
[Presentation] 腎臓吸引圧法における吸引圧を施した腎臓での間質線維芽細胞特異的な遺伝子送達・発現2017
- Author(s)
  大山奈津子、渕上由貴、麓伸太郎、萩森政頼、清水一憲、川上茂
- Organizer
  遺伝子・デリバリー研究会第17回シンポジウム
- Data Source
  KAKENHI-PROJECT-17K19496
[Presentation] Hepatic distribution characteristics of macromolecules in a suctioned liver using the tissue cleaning methods in mice2017
- Author(s)
  Ayana Haraguchi, Yuki Fuchigami, Kaname Ohyama, Shintaro Fumoto, Masayori Hagimori, and Shigeru Kawakami
- Organizer
  11th Young Investigator Symposium on Clinical Pharmaceutical Sciences
- Data Source
  KAKENHI-PROJECT-17K19496
[Presentation] Development of integrin αvβ3 targeted peptide-lipids modified PEGylated liposome for cancer imaging2017
- Author(s)
  Naoya Kato, Masayori Hagimori, Tadaharu Suga, Yuki Fuchigami and Shigeru Kawakami
- Organizer
  第7回日本バイオマテリアル学会九州ブロック講演会
- Data Source
  KAKENHI-PROJECT-17K10366
[Presentation] 非ヘリックスペプチドスペーサーによるがんへの標的性を高めた近赤外蛍光標識PEGリポソームの開発2017
- Author(s)
  加藤直也、萩森政頼、渕上由貴、川上茂
- Organizer
  第12回日本分子イメージング学会
- Data Source
  KAKENHI-PROJECT-17K10366
[Presentation] 腎臓へのin vivo遺伝子導入における遺伝子発現・送達の空間分布2017
- Author(s)
  大山奈津子、渕上由貴、川口真帆、萩森政頼、麓伸太郎、川上茂
- Organizer
  遺伝子・デリバリー研究会第17回夏季セミナー
- Data Source
  KAKENHI-PROJECT-17K19496
[Presentation] 腎臓吸引圧法では尿細管間質の繊維芽細胞および血管周皮細胞に遺伝子導入される2016
- Author(s)
  大山奈津子、渕上由貴、萩森政頼、麓伸太郎、川上茂
- Organizer
  遺伝子・デリバリー研究会第16回夏期セミナー
- Place of Presentation
  やすらぎ伊王島（長崎県・長崎市）
- Year and Date
  2016-09-12
- Data Source
  KAKENHI-PROJECT-26670082
[Presentation] 腎臓吸引圧遺伝子・核酸導入法における腎内遺伝子発現の空間分布評価2016
- Author(s)
  大山奈津子、麓伸太郎、清水一憲、渕上由貴、川上茂
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場、岐阜都ホテル（岐阜県・岐阜市）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26670082
[Presentation] 組織透明化による組織内空間分布評価を利用した外部刺激応答性遺伝子導入システムの評価2016
- Author(s)
  川上茂、西村光洋、小川昂輝、大山奈津子、萩森政頼、麓伸太郎、渕上由貴
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島大学（鹿児島県・鹿児島市）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-26670082
[Presentation] 肝臓への組織吸引圧法における薬物送達特性の評価2016
- Author(s)
  原口綾奈、渕上由貴、萩森政頼、麓伸太郎、川上茂
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島大学（鹿児島県・鹿児島市）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-26670082
[Presentation] Spatial distribution of transgene expression in the kidney in renal suction-mediated transfection method in mice2016
- Author(s)
  Natsuko Oyama, Shintaro Fumoto, Yuki Fuchigami, Masayori Hagimori, Shigeru Kawakami
- Organizer
  The 1st Workshop for Japan-Korea Young Scientists on Pharmaceutics
- Place of Presentation
  京都教育文化センター（京都府・京都市）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-26670082
[Presentation] Renal suction-mediated transfection method can deliver pDNA to tubulointerstitial cells in mice2016
- Author(s)
  Shigeru Kawakami, Natsuko Oyama, Yuki Fuchigami, Megumu Sato, Wang Wei, Masayori Hagimori, Shintaro Fumoto
- Organizer
  日本薬物動態学会第31回年会
- Place of Presentation
  キッセイ文化ホール、松本市総合体育館（長野県・松本市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26670082
[Presentation] 外部刺激制御に基づく遺伝子・核酸デリバリーシステムの開発2016
- Author(s)
  川上　茂
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26670082
[Presentation] 腎臓吸引圧導入法による遺伝子導入部位の評価2015
- Author(s)
  大山奈津子、麓伸太郎、佐藤　萌、清水一憲、渕上由貴、川上茂
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール（長崎県）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670082
[Presentation] 組織吸引圧を利用した遺伝子デリバリー：長期発現持続化と組織内発現の評価2015
- Author(s)
  川上茂、原口綾奈、大山奈津子、渕上由貴、麓伸太郎、清水一憲
- Organizer
  第15回遺伝子・デリバリー研究会夏季セミナー
- Place of Presentation
  定山渓ビューホテル (北海道)
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-26670082
[Presentation] 腎臓への吸引圧核酸導入法を利用した外来遺伝子発現における支配因子の検討2015
- Author(s)
  佐藤　萌、大山奈津子、清水一憲、渕上由貴、川上茂
- Organizer
  遺伝子・デリバリー研究会第15回シンポジウム
- Place of Presentation
  京都薬科大学（京都府）
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-26670082
[Presentation] 超音波照射や組織押圧・吸引圧を利用した遺伝子デリバリー2014
- Author(s)
  川上茂、原口綾奈、西村光洋、橋田　充、渕上由貴
- Organizer
  分子デリバリー研究会：物理と薬学のコラボレーション　2014年度研究会
- Place of Presentation
  慶應義塾大学矢上キャンパス(神奈川県)
- Year and Date
  2014-12-05
- Invited
- Data Source
  KAKENHI-PROJECT-26670082
[Presentation] 医療機器とDDSの融合によるメディカルイノベーション2014
- Author(s)
  川上茂
- Organizer
  立命館大学　バイオメディカルデバイス研究センターシンポジウム2014
- Place of Presentation
  立命館大学ローム記念館（滋賀県）
- Year and Date
  2014-09-17
- Invited
- Data Source
  KAKENHI-PUBLICLY-25114705
[Presentation] Anti-tumor effect of NF-kappaB decoy transfection into tumor-associated macrophages using mannose-modified bubble lipoplexes in Ehrlich ascites carcinoma-bearing mice2014
- Author(s)
  Y. Kono, S. Kawakami, Y. Higuchi, K. Maruyama, F. Yamashita, M. Hashida
- Organizer
  The 4th International Synmposium on Carcinogenic Spiral Infection, Immunity, and Cancer
- Place of Presentation
  京王プラザホテル札幌（北海道）
- Data Source
  KAKENHI-PUBLICLY-25114705
[Presentation] Targeted gene delivery using external stimuli2014
- Author(s)
  S. Kawakami
- Organizer
  The 1st International Symposium, Dejima Challenge for Therapeutic Innovation
- Place of Presentation
  長崎大学文教スカイホール(長崎県)
- Invited
- Data Source
  KAKENHI-PUBLICLY-25114705
[Presentation] Enhancement by cyclodextrin of cell surface modification with PEGylated lipid2013
- Author(s)
  Yoshimasa Takafuji, Yuriko Higuchi, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Hawaii Convention Center
- Data Source
  KAKENHI-PROJECT-24650262
[Presentation] マンノース修飾バブルリポソームを用いたNF-B活性化制御による腫瘍関連マクロファージのphenotype変化2013
- Author(s)
  河野裕允、川上茂、樋口ゆり子、鈴木亮、丸山一雄、山下富義、橋田充
- Place of Presentation
  ウインクあいち(愛知県)
- Year and Date
  2013-05-23
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] マンノース修飾バブルリポソームを用いたNF-kappaB 活性制御による腫瘍関連マクロファージのphenotype 変化2013
- Author(s)
  河野裕允、川上茂、樋口ゆり子、鈴木亮、丸山一雄、山下富義、橋田充
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインクあいち(愛知県)
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] マンノース修飾バブルリポソームを用いたNF-kappaB活性制御による腫瘍関連マクロファージのphenotype変化2013
- Author(s)
  河野裕允、川上茂、樋口ゆり子、鈴木亮、丸山一雄、山下富義、橋田充
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインクあいち（愛知県）
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] 体外からの刺激に応答して機能を発揮する遺伝子デリバリーシステムの開発2013
- Author(s)
  川上茂
- Organizer
  バイオマテリアル学会九州講演会2013
- Place of Presentation
  熊本大学くすの木会館(熊本県)
- Year and Date
  2013-09-20
- Invited
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] マンノース修飾バブルリポソームを用いたNF-kappaB活性化制御による腫瘍関連マクロファージのphenoype変化2013
- Author(s)
  河野裕允、川上　茂、樋口ゆり子、鈴木　亮、丸山一雄、山下富義、橋田　充
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインクあいち(愛知県)
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] Ultrasound triggered doxorubicin loaded microbubbles for effective therapeutic outcomes in melanoma2013
- Author(s)
  Rodi Abdalｋader, Mitsuru Hashida, Shigeru Kawakami, Ryo Suzuki, Kazuo Maruyama
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] マンノース６リン酸受容体を標的としたがん細胞指向性新規糖修飾リポソームの開発2013
- Author(s)
  松田顕也、川上茂、安藤弘宗、樋口ゆり子、山下富義、木曽真、橋田充
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ（京都府）
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] NF-kB decoyの腫瘍関連マクロファージ選択的DDSの開発：TAM phenotypeの再分化の誘導評価2013
- Author(s)
  河野裕允、川上茂、樋口ゆり子、山下富義、橋田充
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] Inhibition of tumor growth by NF-kappaB decoy transfection into TAM using mannose-modified bubble lipoplexes in mice2013
- Author(s)
  河野裕允、川上茂、鈴木亮、丸山一雄、橋田充
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] Inhibition of tumor growth by NF-κ B decoy transfection into TAM using mannose-modified bubble lipoplexes in mice2013
- Author(s)
  河野裕允、川上茂、鈴木亮、丸山一雄、橋田充
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-10-04
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] 外部刺激を利用した標的指向型遺伝子・核酸送達システムの開発2013
- Author(s)
  川上　茂
- Organizer
  遺伝子・デリバリー研究会第１３回夏季セミナー
- Place of Presentation
  ハワイプリンスホテルワイキキ(ハワイ)
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] Ultrasound triggered doxorubicin loaded microbubbles for effective therapeutic outcomes in melanoma2013
- Author(s)
  R. Abdalkader, M. Hashida, S. Kawakami, R. Suzuki, K. Maruyama
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-10-04
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] ヘマトポルフィリン内封PEG修飾リポソームを用いた超音波力学療法の癌治療効果の評価2013
- Author(s)
  河野裕允、川上　茂、山下富義、橋田　充
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ（京都府）
- Data Source
  KAKENHI-PUBLICLY-25114705
[Presentation] 外部刺激を利用した標的指向型遺伝子・核酸送達システムの開発2013
- Author(s)
  川上茂
- Organizer
  遺伝子・デリバリー研究会第13回夏季セミナー
- Place of Presentation
  ハワイプリンスホテルワイキキ(ハワイ)
- Year and Date
  2013-07-24
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] 短鎖PEG脂質による幹細胞表面修飾と細胞間接着の関係2013
- Author(s)
  小田敬昌、樋口ゆり子、高藤義正、川上茂、山下富義、橋田充
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ(京都)
- Data Source
  KAKENHI-PROJECT-24650262
[Presentation] PEG脂質を用いた間葉系幹細胞修飾における超音波照射による修飾率改善2012
- Author(s)
  樋口ゆり子、大城康平、高藤義正、川上茂、山下富義、橋田充
- Organizer
  日本薬物動態学会第27年会
- Place of Presentation
  タワーホール船堀(東京)
- Data Source
  KAKENHI-PROJECT-24650262
[Presentation] phiC31インテグラーゼを用いたマウス肝臓でのHGF発現の長期持続化と肝線維症治療効果の評価2012
- Author(s)
  梅本佳昭、川上茂、樋口ゆり子、山下富義、橋田充
- Organizer
  日本薬学会13年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] 外部刺激を利用したin vivo核酸デリバリー法の開発と評価2012
- Author(s)
  川上　茂
- Organizer
  日本薬剤学会第27年会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Invited
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] 外部刺激を利用した遺伝子・核酸デリバリーシステム2012
- Author(s)
  川上茂
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2012-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] 外部刺激を利用した遺伝子・核酸デリバリーシステム2012
- Author(s)
  川上　茂
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Invited
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] NF-kB を標的とする抑制性オリゴ核酸による癌微小環境中のマクロファージの免疫再賦活化2012
- Author(s)
  河野裕允、川上茂、樋口ゆり子、山下富義、橋田充
- Place of Presentation
  仙台市民会館(宮城県)
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] 外部刺激を利用したin vivo核酸デリバリー法の開発と評価2012
- Author(s)
  川上茂
- Organizer
  日本薬剤学会第27年会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2012-05-25
- Invited
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] GRP78 siRNAリポプレックスによるがん細胞アポトーシスの誘導と抗がん剤耐性の克服2012
- Author(s)
  松村一史、川上茂、山下富義、橋田充
- Organizer
  日本薬学会第132回年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] 表面プラズモン共鳴測定によるhICAM-1とICAM-1認識配列を含むペプチドとの親和性の評価2012
- Author(s)
  山口徹、樋口ゆり子、川上茂、山下富義、橋田充
- Organizer
  創剤フォーラム第18回若手研究会
- Place of Presentation
  徳島大学薬学部長井記念ホール(徳島)
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-24650262
[Presentation] PEG脂質を用いた間葉系幹細胞表面修飾における超音波の効果2012
- Author(s)
  大城康平、樋口ゆり子、高藤義正、川上茂、山下富義、橋田充
- Organizer
  第62回日本薬学会近畿支部総会・大会
- Place of Presentation
  武庫川女子大学薬学部浜甲子園キャンパス(兵庫)
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-24650262
[Presentation] NF-ｋBを標的とする抑制性オリゴ核酸による癌微小環境中のマクロファージの免疫再賦活化2012
- Author(s)
  河野裕允、川上茂、樋口ゆり子、山下富義、橋田充
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム２０１２
- Place of Presentation
  仙台市民会館（宮城県）
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] PEG脂質を用いた間葉系幹細胞修飾における超音波照射による修飾率改善2012
- Author(s)
  樋口ゆり子、大城康平、高藤義正、川上　茂、山下富義、橋田　充
- Organizer
  日本薬物動態学会第27年会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-24650262
[Presentation] phiC31インテグラーゼを用いたマウス肝臓でのHGF発現の長期持続化と肝線維症治療効果の評価2012
- Author(s)
  梅本佳昭、川上茂、樋口ゆり子、山下富義、橋田充
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] Evalution of the inhibition of NF-κB activity by using decoy oligonucleotides on the immune response of macrophages cultured in various cancer cells conditioned medium2012
- Author(s)
  Yusuke Kono, Shigeru Kawakami, Yuriko Higuchi, Fumiyoshi Yamashita, Mitsuru Hashida
- Organizer
  第6回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  京都大学薬学部（京都府）
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] Anti-inflammatory effects by icam-1 siRNA delivery using mannose-modified bubble lipoplexes and ultrasound exposure2011
- Author(s)
  S. Kawakami, K. Un, R. Suzuki, K. Maruyama, Y. Higuchi, F. Yamashita, M. Hashida
- Organizer
  日本薬物動態学会第26年会
- Place of Presentation
  広島国際会議場(広島県)
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] phiC31 integrase-mediated long-term gene expression in the cultured renal cell lines and murine kidney2011
- Author(s)
  Shigeru Kawakami, Yuki Otani, Hidefumi Mukai, Yoshiaki Umemoto, Fumiyoshi Yamashita, and Mitsuru Hashida
- Organizer
  AMERICAN SOCIETY of GENE & CELL THERAPY(ASGCT)
- Place of Presentation
  シアトル(アメリカ合衆国)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] 細胞特異的核酸医薬デリバリーを目的とした超音波応答性マンノース修飾リポソームの開発2011
- Author(s)
  川上茂、運敬太、橋田充
- Organizer
  第27回日本DDS学会学術集会
- Place of Presentation
  東京大学本郷キャンパス(東京都)
- Year and Date
  2011-06-10
- Invited
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] 静電的相互作用を利用した葉酸修飾型遺伝子ベクターの開発2011
- Author(s)
  黒崎友亮、川上茂、橋田充、佐々木均
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  東京
- Year and Date
  2011-05-29
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] Evalustion of endosomal escape of lysine-histidine dendrons by live cell imaging2011
- Author(s)
  Yuriko Higuchi, Kai-ling Chang, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida
- Organizer
  日本薬物動態学会第26年会
- Place of Presentation
  広島国際会議場(広島県)
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] 体内埋込型マイクロシステムを用いた腎臓への遺伝子導入法の開発2011
- Author(s)
  林昴司、清水一憲、森勇樹、川上茂、小西聡、橋田充
- Organizer
  第27回日本DDS学会学術集会
- Place of Presentation
  東京大学本郷キャンパス(東京都)
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] phiC31 integrase-mediated long-term gene expression in the cultured renal cell lines and murine kidney2011
- Author(s)
  S.Kawakami, Y.Otani, H.Mukai, Y.Umemoto, F.Yamashita, M.Hashida
- Organizer
  AMERICAN SOCIETY of GENE & CELL THERAPY (ASGCT) 14th Annual Meeting
- Place of Presentation
  シアトル(アメリカ合衆国)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] Enhancement of gene expression by transcriptional activation using doxorubicin-loaded liposome/pDNA complexes2011
- Author(s)
  Y. Kono, K. Un, M. Yoshida, F. Yamashita, S. Kawakami, M. Hashida
- Organizer
  第5回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  名古屋大学医学部附属病院(愛知県)
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] Gene transfer characteristics of an ultrasound-responsive and mannose-modified bubble lipoplex2011
- Author(s)
  Kawakami S, Un K, Suzuki R, Maruyama K, Higuchi Y, Yamashita F, Hashida M
- Organizer
  International Conference on Biomaterials Sciences
- Place of Presentation
  Tsukuba
- Year and Date
  2011-03-17
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] Gene transfection characteristics of an ultrasound-responsive and mannose-modified bubble lipoplex2011
- Author(s)
  S.Kawakami, K.Un, R.Suzuki, K.Maruyama, Y.Higuchi, F.Yamashita, M.Hashida
- Organizer
  International Conference on Biomaterials Science 2011
- Place of Presentation
  International Congress Center (Tsukuba, Japan)
- Year and Date
  2011-03-17
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] 超音波応答性マンノース修飾リポソームを用いたsiRNA導入による効率的な細胞選択的遺伝子発現抑制法の開発2011
- Author(s)
  吉田允、川上茂、運敬太、山下富義、橋田充
- Organizer
  第61回日本薬学会近畿支部大会
- Place of Presentation
  神戸学院大学ポートアイランドキャンパス(兵庫県)
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] 三重構造を有した生体分解型遺伝子ベクターの構築2011
- Author(s)
  黒崎友亮、川上茂、橋田充、佐々木均
- Organizer
  第27回日本DDS学会
- Place of Presentation
  東京
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-21390010
[Presentation] Anti-inflammatory effects by icam-1 siRNA delivery using mannose-modified bubble lipoplexes and ultoasound exposure2011
- Author(s)
  S.Kawakami, K.Un, R.Suzuki, K.Maruyama, Y.Higuchi, F.Yamashita, M.Hashida
- Organizer
  日本薬物動態学会第26年会
- Place of Presentation
  広島国際会議場(広島県)
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] 細胞特異的核酸医薬デリバリーを目的とした超音波応答性マンノース修飾リポソームの開発2011
- Author(s)
  川上茂、運敬太、橋田充
- Organizer
  第27回日本DDS学会学術集会
- Place of Presentation
  東京大学本郷キャンパス(東京都)(招待講演)
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PROJECT-23689003
[Presentation] Gaussia luciferaseを用いたφC31 integraseによるin vivo長期遺伝子発現の簡便な評価法の開発2010
- Author(s)
  梅本佳昭、川上茂、大谷祐基、山下富義、橋田充
- Organizer
  第60回日本薬学会近畿支部会
- Place of Presentation
  摂南大学(大阪)
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] CpG DNA lipoplex経鼻投与による肺転移・腹膜播種抑制の機構解明2010
- Author(s)
  周舒文, 川上茂, 山下富義, 橋田充
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山コンベンションセンター(岡山)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-17016035
[Presentation] φC31 integraseによるin vivo長期遺伝子発現の簡便な評価を目的とした分泌型luciferase発現pDNAの構築2010
- Author(s)
  梅本佳昭、川上茂、大谷祐基、山下富義、橋田充
- Organizer
  遺伝子・デリバリー研究会第10回夏期セミナー
- Place of Presentation
  琵琶湖ホテル(滋賀)
- Year and Date
  2010-09-01
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] φC31 integraseによるin vivo長期遺伝子発現の簡便な評価を目的とした分泌型luciferase発現pDNAの構築2010
- Author(s)
  梅本佳昭、川上茂、大谷祐基、山下富義、橋田充
- Organizer
  遺伝子・デリバリー研究会第10回夏期セミナー、琵琶湖ホテル(滋賀)
- Place of Presentation
  琵琶湖ホテル(滋賀)
- Year and Date
  2010-09-01
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] マンノース修飾バブルリポプレックスと超音波照射による標的細胞選択的かつ高効率遺伝子導入法の開発2010
- Author(s)
  運敬太、川上茂、鈴木亮、丸山一雄、山下富義、橋田充
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] 臓器特異的遺伝子発現制御を目的とする組織押圧核酸導入法の開発と評価2010
- Author(s)
  向井英史、川上茂、橋田充
- Organizer
  第60回日本薬学会近畿支部会
- Place of Presentation
  摂南大学(大阪)
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] 臓器特異的遺伝子発現制御を目的とする組織押圧核酸導入法の開発と評価2010
- Author(s)
  向井英史、川上茂、橋田充
- Organizer
  第60回日本薬学会近畿支部会
- Place of Presentation
  摂南大学(大阪)(招待講演)
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] CpGDNA lipoplexp経鼻投与による肺転移・腹膜播種抑制の機構解明2010
- Author(s)
  周舒文, 川上茂, 山下富義, 橋田充
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山コンベンションセンター(岡山)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-17016035
[Presentation] 超音波応答性リポソームを用いたin-vivo遺伝子導入法における転写因子活性化と炎症性サイトカイン産生の評価2010
- Author(s)
  運敬太、川上茂、鈴木亮、丸山一雄、樋口ゆり子、山下富義、橋田充
- Organizer
  遺伝子・デリバリー研究会第10回シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2010-06-02
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] 超音波応答性リポソームを用いたin-vivo遺伝子導入法における転写因子活性化と炎症性サイトカイン産生の評価2010
- Author(s)
  運敬太、川上茂、鈴木亮、丸山一雄、樋口ゆり子、山下富義、橋田充
- Organizer
  遺伝子・デリバリー研究会第10回シンポジウム
- Place of Presentation
  北海道大学学術交流会館(札幌)
- Year and Date
  2010-06-02
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] マンノース修飾バブルリポプレックスと超音波照射による標的細胞選択的かつ高効率遺伝子導入法の開発2010
- Author(s)
  運敬太、川上茂、鈴木亮、丸山一雄、山下富義、橋田充
- Organizer
  日本薬学会第130年会
- Place of Presentation
  ホテルグランヴィア岡山(岡山)
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] Cancer immunotherapy using glycosylated liposomes2009
- Author(s)
  Kawakami S, Hashida M
- Organizer
  日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] 新規マンノース修飾バブルリポプレックスと超音波の併用による標的細胞選択的in vivo遺伝子導入法の開発2009
- Author(s)
  運敬太、川上茂、丸山一雄、山下富義、橋田充
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡県コンベンションセンター(静岡)
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] Cancer immunotherapy using glycosylated liposomes2009
- Author(s)
  S.Kawakami, M.Hashida
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] アミノ酸デンドリマーを用いたDNAアプタマーの生体内応用に向けたアプローチ:癌細胞指向型アプタマー/デンドリマー結合体の開発2009
- Author(s)
  増田真理恵、川上茂、Wijagkanalan Wassana、山下富義、橋田充
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京ドームホテル(東京)
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-17016035
[Presentation] アミノ酸デンドリマーを用いたDNAアプタマーの生体内応用に向けたアプローチ:癌細胞指向型アプタマー/デンドリマー結合体の開発2009
- Author(s)
  増田真理恵、川上茂、Wijagkanalan Wassana、山下富義、橋田充
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京ドームホテル(東京都)
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-17016035
[Presentation] Cancer immuno -therapy using glycosylated liposomes2009
- Author(s)
  Kawakami S, Hashida M
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] Development and evaluation of organ-press mediated in vivo gene transfection methods of plasmid DNA and siRNA.2009
- Author(s)
  Kawakami S, Mukai H, Hashida M
- Organizer
  The 10 the US-Japan Symposium on Drug Delivery Systems
- Place of Presentation
  Maui, Hawaii
- Year and Date
  2009-12-17
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] Enhanced growth inhibition of metastatic lung tumor by intravenous injection of IL12-ATRA-lipoplexes in mice2009
- Author(s)
  Pensri Charoensit, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡県コンベンションアーツセンター(静岡)
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-17016035
[Presentation] Glycosylated liposomes for the targeted delivery of siRNA and CpG DNA2008
- Author(s)
  Shigeru Kawakami, Yuriko Higuchi, Fumivoshi Yamashita, Mitsuru Hashida
- Organizer
  第14回日本遺伝子治療学会
- Place of Presentation
  札幌医科大学
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] Glycosylated liposomes for drug nucleic acids delivery2008
- Author(s)
  Shigeru Kawakami, Yuriko Higuchi, Mitsuru Hashids
- Organizer
  第11回国際リポソーム研究会議
- Place of Presentation
  黄浜シンポジア
- Year and Date
  2008-07-19
- Data Source
  KAKENHI-PROJECT-17016035
[Presentation] 抗体-アミノ酸デンドリマーコンジュゲートによるHER2選択的細胞内デリバリー2008
- Author(s)
  宮野拓也、川上茂、新留琢郎、橋田充
- Organizer
  第24回日本dds学会
- Place of Presentation
  六本木アカデミーヒルズ(東京)
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-17016035
[Presentation] Inhalation of Dexamethasone Palmitate Encapsulated Mannosylated Liposomes Efficiently Ameliorates LPS-Induced Lung Inflammation in Rats2008
- Author(s)
  Wassana Wijagkanalan, Shigeru Kawakami, Mariko Kuroda, Hitoshi Sasaki, Fumiyoshi Yamashita, Mitsuru Hashida
- Organizer
  第11回国際リポソーム研究会議
- Place of Presentation
  横浜
- Year and Date
  2008-07-19
- Data Source
  KAKENHI-PROJECT-18209006
[Presentation] Inhalation of Dexamethasone Palmitate Encapsulated Mannosylated Liposomes Efficiently Ameliorates LPS-Induced Lung Inflammation in Rats2008
- Author(s)
  Wassana wijagkanalan, Shigeru Kawakami, Mariko Kuroda, Hitoshi Sasaki, Fumiyoshi Yamashita, Mitsuru Hashida
- Organizer
  第11回国際リボソーム研究会議
- Place of Presentation
  横浜シンポジア
- Year and Date
  2008-07-19
- Data Source
  KAKENHI-PROJECT-18209006
[Presentation] Targeting of inhaled dexamethasone palmitate using mannosylated liposomes in an endotoxin-induced lung inflammation model2008
- Author(s)
  Wijagkanalan W, Kawakami S, Teshima M, Sasaki H, Hashida M
- Organizer
  日本薬剤学会第23年会
- Place of Presentation
  札幌
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] Glycosylated liposomes for drug nucleic acids delivery2008
- Author(s)
  Shigeru Kawakami, Yuriko Higuchi, Mitsuru Hashida
- Organizer
  第11回国際リポソーム研究会議
- Place of Presentation
  横浜シンポジア(神奈川)
- Year and Date
  2008-07-19
- Data Source
  KAKENHI-PROJECT-17016035
[Presentation] Evaluation of proinflammatory cytokine production induced by siRNA/polyethylenimine complexes2008
- Author(s)
  Pensri Charoensit, 川上茂, 山下富義, 橋田充
- Organizer
  第24回日本DDS学会
- Place of Presentation
  六本木アカデミーヒルズ
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-18209006
[Presentation] argeting of inhaled dexamethasone palmitate using mannosy lated liposomes in an endotoxin-induced lung inflammation model2008
- Author(s)
  Wassana Wijagkanalan, Shigeru Kawakami, Mugen leshima, Hitoshi Sasaki, Mitsuru Hashida
- Organizer
  日本薬剤学会第23年会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] Glycosylated liposomes for drug and nucleic acids delivery2008
- Author(s)
  Kawakami S, Higuchi Y, Hashida M
- Organizer
  11th Liposome Research Days
- Place of Presentation
  Yokohama
- Year and Date
  2008-07-21
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] Evaluation of proinflammatory cytokine production inducedby siRNA/polyethylenimine complexes2008
- Author(s)
  Pensri Charoensit、川上茂、山下富義、橋田充
- Organizer
  第24回日本DDS学会
- Place of Presentation
  東京
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-18209006
[Presentation] Glycosylated liposomes for drug and nucleic acids delivery2008
- Author(s)
  Kawakami S, Higuchi Y, Hashida M
- Organizer
  11th Liposome Research Days
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-07-21
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] 抗体-アミノ酸デンドリマーコンジュゲートによるHER2選択的細胞内デリバリー2008
- Author(s)
  宮野拓也、川上茂、新留琢郎、橋田充
- Organizer
  第24回日本DDS学会
- Place of Presentation
  六本木アカデミーヒルズ
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-17016035
[Presentation] 圧力による腎臓への核酸導入法2008
- Author(s)
  向井英更、川上茂、馬凡、高橋晴之、山下富義、橋阻充
- Organizer
  遺伝子・デリバリー研究会第8回シンポジウム
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2008-05-09
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] Intranasally Administered CpG DNA /Cationic Liposome Complexes Prevents Lung Metastases in Mice2008
- Author(s)
  Shuwen Zhou, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida
- Organizer
  第11回国際リポソーム研究会議
- Place of Presentation
  横浜シンポジア(神奈川)
- Year and Date
  2008-07-19
- Data Source
  KAKENHI-PROJECT-17016035
[Presentation] Glycosylated liposomes for the targeted delivery of siRNA and CpG DNA2008
- Author(s)
  Kawakami S, Higuchi Y, Yamashita F, Hashida M
- Organizer
  第14回日本遺伝子治療学会年会
- Place of Presentation
  札幌
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] Intranasally Administered CpG DNA/Cationic Liposome Complexes Prevents Lun Metastases in Mice2008
- Author(s)
  Shuwen-Zhou, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida
- Organizer
  第11回国際リポソーム研究会議
- Place of Presentation
  横浜シンポジア
- Year and Date
  2008-07-19
- Data Source
  KAKENHI-PROJECT-17016035
[Presentation] Evaluation and development of nano-carriers using imaging technology2007
- Author(s)
  Kawakami S, Hashida M
- Organizer
  1st Asian Biomaterial Conference
- Place of Presentation
  Tsukuba, Japan
- Year and Date
  2007-12-08
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] Cationic liposomes formulations for the effective treatment of peritoneal dissemination by CpG DNA2007
- Author(s)
  Kuramoto Y, Kawakami S, Hashida M
- Organizer
  日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] Cationic liposomes formulations for the effective treatment of peritoneal dissemination by CpG DNA2007
- Author(s)
  Kuramoto Y, Kawakami S, Hashida M
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19689005
[Presentation] 樹状細胞選択的遺伝子送達キャリアを用いた新規DNAワクチン療法の開発2006
- Author(s)
  川上茂、橋田充
- Organizer
  第65回日本癌学会総会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2006-09-29
- Data Source
  KAKENHI-PROJECT-17016035
[Presentation] 組織吸引圧を利用した部位特異的遺伝子・核酸導入システムの開発
- Author(s)
  川上茂、原口綾奈、大山奈津子、張　光元、橋田　充、清水一憲、渕上由貴
- Organizer
  遺伝子・デリバリー研究会第14回夏季セミナー
- Place of Presentation
  阿蘇いこいの村（熊本県）
- Year and Date
  2014-08-20 – 2014-08-21
- Data Source
  KAKENHI-PROJECT-26670082
[Presentation] 表面プラズモン共鳴測定によるhICAM-1とICAM-1認識配列を含むペプチドとの親和性の評価
- Author(s)
  山口徹、樋口ゆり子、川上茂、山下富義、橋田充
- Organizer
  創剤フォーラム第18回若手研究会
- Place of Presentation
  徳島大学薬学部長井記念ホール（徳島県）
- Data Source
  KAKENHI-PROJECT-24650262
[Presentation] PEG脂質修飾幹細胞と血管内皮細胞との細胞間接着に関するリアルタイムイメージング解析
- Author(s)
  高藤義正、樋口ゆり子、川上茂、山下富義、橋田充
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ
- Data Source
  KAKENHI-PROJECT-24650262
[Presentation] PEG脂質を用いた間葉系幹細胞表面修飾における超音波の効果
- Author(s)
  大城康平、樋口ゆり子、高藤義正、川上　茂、山下富義、橋田　充
- Organizer
  第62回日本薬学会近畿支部総会・大会
- Place of Presentation
  武庫川女子大学薬学部浜甲子園キャンパス（兵庫県）
- Data Source
  KAKENHI-PROJECT-24650262
[Presentation] 細胞選択的遺伝子導入を目的とした超音波応答性糖修飾バブルリポプレックスの開発
- Author(s)
  川上茂
- Organizer
  日本超音波医学会第87回学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-05-09 – 2014-05-11
- Invited
- Data Source
  KAKENHI-PUBLICLY-25114705
[Presentation] 糖修飾バブルリポソームを利用した超音波増感剤による細胞傷害機構の評価
- Author(s)
  古海沙喜、渕上由貴、川上　茂
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎新聞文化ホール（長崎県）
- Year and Date
  2015-05-21 – 2015-05-23
- Data Source
  KAKENHI-PUBLICLY-25114705
[Presentation] Development of mannosylated bubble liposomes encapsulated drugs for cell-selective delivery into tumor-associated macrophages
- Author(s)
  S. Furumi, M. Yamaoka, E. Nishigami, Y. Fuchigami, S. Kawakami
- Organizer
  The 5th International Symposium on Carcinogenic Spiral Infection
- Place of Presentation
  神戸国際会議場（兵庫県）
- Year and Date
  2015-02-26 – 2015-02-27
- Data Source
  KAKENHI-PUBLICLY-25114705
[Presentation] 組織押圧・吸引圧を利用した腎臓への遺伝子導入における遺伝子発現部位ならびに簡易式組織吸引デバイスの評価
- Author(s)
  大山奈津子、佐藤　萌、麓伸太郎、清水一憲、渕上由貴、川上　茂
- Organizer
  第31回日本薬学会九州支部大会
- Place of Presentation
  第一薬科大学（福岡県）
- Year and Date
  2014-12-06 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-26670082
[Presentation] 外部刺激を利用した標的指向性DDSの開発
- Author(s)
  川上茂
- Organizer
  第63回高分子討論会
- Place of Presentation
  長崎大学スカイホール（長崎県）
- Year and Date
  2014-09-24 – 2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-26670082
[Presentation] 腫瘍関連マクロファージ選択的薬物送達を目的とした超音波応答性マンノース修飾バブルリポソームの開発
- Author(s)
  渕上由貴、古海沙喜、山岡真理子、橋田充、川上茂
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（兵庫県）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PUBLICLY-25114705
[Presentation] 肝臓への遺伝子導入のための組織吸引デバイスの開発と急性肝炎モデルマウスでの評価
- Author(s)
  原口綾奈、渕上由貴、麓伸太郎、清水一憲、張　光元、橋田　充、川上　茂
- Organizer
  第31回日本薬学会九州支部大会
- Place of Presentation
  第一薬科大学（福岡県）
- Year and Date
  2014-12-06 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-26670082
[]
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[]

1. HASHIDA Mitsuru (20135594)

# of Collaborated Projects: 7 results

# of Collaborated Products: 56 results
2. YAMASHITA Fumiyoshi (30243041)

# of Collaborated Projects: 6 results

# of Collaborated Products: 42 results
3. YURIKO Higuchi (40402797)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
4. HAGIMORI Masayori (40446125)

# of Collaborated Projects: 3 results

# of Collaborated Products: 29 results
5. 麓伸太郎 (70380988)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
6. 日宇健 (00404260)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
7. NAKAMURA Junzo (30115901)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. NISHIKAWA Makiya (40273437)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
9. SASAKI Hitoshi (00170689)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
10. KUROSAKI Tomoaki (00582016)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
11. KODAMA Yukinobu (50448510)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
12. HASHIDA Yasuhiko (30512462)

# of Collaborated Projects: 2 results

# of Collaborated Products: 26 results
13. NAKASHIMA Mikiro (00260737)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. SAKAEDA Toshiyuki (00304098)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. NISHIDA Koyo (20237704)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. 向井英史 (60570885)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
17. 松尾彩香 (80913342)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
18. 松尾孝之 (00274655)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
19. 吉田道春 (00795437)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
20. TO Hideto (90346809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
21. KITAHARA Takashi (30380934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
22. WADA Mitsuhiro (40295093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. MUKAI Takahiro (30284706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. Hidetoshi Arima (50260964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 清水一憲 (70402500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
26. 中村忠博 (60882199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 山下親正 (30622188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 室高広 (10832834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 北岸宏亮 (60448090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 山吉麻子 (70380532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
31. 斉藤貴志 (90360552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 水上修作 (00508971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
33. 毛利浩太 (30723697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 梅田雅孝 (20750053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 辻良香 (10866297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 古賀智裕 (90537284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 櫻井文教 (70370939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 鎌田春彦 (00324509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 立花雅史 (80513449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 清水かほり (50737749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 高島由季 (70236214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. ABDALKADER Rodi (20839964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 吉田光一 (20393457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
44. 氏福健太 (20437867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. 馬場史郎 (30530430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. FUCHIGAMI Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
47. OYAMA Natsuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
48. ITAKA Keiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWAKAMI Shigeru 川上 茂

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Development of nucleic acid drug delivery and genome editing technologies for various cells in the brainPrincipal Investigator

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Development of innovative T cell-inducing vaccine drug based on mRNA deliveryPrincipal Investigator

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Development of multi color deep imaging of cancer tissues and spatial distribution control of drug deliveryPrincipal Investigator

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Elucidation of mechano-transfection and mechano-sensing mechanism using a living tissuePrincipal Investigator

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Development of gene delivery system using the tissue press/suction methodPrincipal Investigator

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KAWAKAMI Shigeru 川上茂