FUJISAWA Takuo 藤澤拓生

Researcher Number	20325096
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2011: 岡山大学, 大学病院, 助教 2010: Okayama University, 岡山大学病院, 助教 2010: 岡山大学, 病院, 助教 2009: Okayama University, 大学病院, 助教 2007: 岡山大, 医歯(薬)学総合研究科, 助手 … More 2006: Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Research Assistant, 大学院医歯薬学総合研究科, 助手 2005 – 2006: Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Research Associate, 大学院・医歯薬学総合研究科, 助手 2001 – 2004: 岡山大学, 大学院・医歯学総合研究科, 助手 2000: 岡山大学, 歯学部, 助手 Less
Review Section/Research Field	Principal Investigator Prosthetic dentistry / 補綴理工系歯学 / 補綴理工系歯学 Except Principal Investigator 補綴理工系歯学 / 補綴理工系歯学
Keywords	Principal Investigator 細胞増殖 / CTGF / cell proliferation / cell attachment / tissue engineering / hydroxyapatite / bone regeneration / connective tissue growth factor / multilineage differentiation / mesenchymal stem cell … More / 細胞遊走能 / 血管内皮細胞 / 細胞接着 / 再生工学 / ハイドロキシアパタイト / 骨再生 / 結合組織成長因子(CTGF) / 多分化能 / 間葉系幹細胞 / Nitric Oxide / Apoptosis / Cartilage Degradation / Articular Cartilage / Gene Therapy / Mechanical Stress / Osteoarthritis / 結合組織成長因子 / 細胞分化 / NO / 軟骨細胞 / 一酸化窒素 / アポトーシス / 軟骨破壊 / 軟骨修復 / 遺伝子導入 / メカニカルストレス / 変形性顎関節症 / 再生医療 / 骨形成 / 低分子化合物 / BMP-2 / 骨髄由来間質細胞 / siRNA / BMPアンタゴニスト / BMP / 質細胞 / 軟骨再生 / 細胞移植 / 組織再生 / 耳介軟骨 … More Except Principal Investigator 変形性顎関節症 / BMP-2 / sod-1 / xab-2 / Osteoarthritis / 骨再生 / チタン / 遺伝子発現 / オッセオインテグレーション / 骨芽細胞 / インプラント / Escherichia coli / large animal / carrier / periodontal disease / implant / bone regeneration / gelatin hydrogels / 大腸菌 / 大動物 / キャリア / 歯周病 / ゼラチンハイドロゲル / joint injection therapy / anti cytokine therapy / etanercept / type II soluble tumor necrosis factor / osteoarthritis of TMJ / エンブレル【○!R】 / LTαレセプター製剤 / 完全ヒト型可溶性TNFα / 可溶型腫瘍壊死因子受容体 / 関節腔内注入療法 / 抗サイトカイン療法 / エタネルセプト / II型腫瘍壊死因子可溶性受容体 / sTNFR-I,II / TNFα / 可溶性レセプター / 腫瘍壊死因子 / 変形性顎間節症 / 潰瘍壊死因子α / 腫瘍壊死因子α / 可溶性腫瘍壊死因子受容体 / galection-1 / Osseointegration / Titanium / Osteoblasts / bone marrow cells / 幹葉系幹細胞 / 骨組織再生 / チタン特異的遺伝子 / デンタルインプラント / galectin-1 / 培養骨芽細胞 / 間葉系幹細胞 / Chondrocyte / Adenovirus / Gene therapy / Articular cartilage / Mechanical stress / 細胞増殖 / 細胞分化 / 培養軟骨細胞 / CTGF / アデノウイルスベクター / 遺伝子導入 / 組織変化 / 動物モデル / マトリックスメタロプロテアーゼ / 一酸化窒素 / アポトーシス / 軟骨破壊 / 軟骨細胞 / アデノウイルス / 遺伝子治療 / 関節軟骨 / メカニカルストレス / 表面性状 / 骨髄間葉系幹細胞 / 表面粗さ / DNA / IV型コラーゲン / MMP-3 / 遺伝子多型(SNP) / 顎関節症 Less

低分子化合物ライブラリーを用いた骨形成過程における新規BMP2活性制御因子の探索Principal Investigator
- Principal Investigator
  
  藤澤拓生
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Prosthetic dentistry
- Research Institution
  Okayama University
Development of a novel method of promoting alveolar bone formation by controlling the expression of BMP antagonist.Principal Investigator
- Principal Investigator
  
  FUJISAWA Takuo
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Prosthetic dentistry
- Research Institution
  Okayama University
結合組織成長因子(CCN2/CTGF)を用いた顎顔面領域の三次元軟骨再生Principal Investigator
- Principal Investigator
  
  藤澤拓生
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  補綴理工系歯学
- Research Institution
  Okayama University
Bone regeneration with degradable hydrogels and genetically modified, recombinant human BMP-2 with two additional repeats of the heparin-binding domain.
- Principal Investigator
  
  NAWACHI Kumiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  補綴理工系歯学
- Research Institution
  Okayama University
The practice of anti-cytokine treatment for temporomandibular joint osteoarthritis
- Principal Investigator
  
  UEHARA Junji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  補綴理工系歯学
- Research Institution
  Okayama University
Establishment of an autologous cell transplantion method using mesenchymal stem cells for alveolus bone regeneration.Principal Investigator
- Principal Investigator
  
  FUJISAWA Takuo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  補綴理工系歯学
- Research Institution
  OKAYAMA UNIVERSITY
口腔インプラントの骨結合獲得難易度を予測する生物学的診断法の開発
- Principal Investigator
  
  窪木拓男
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  補綴理工系歯学
- Research Institution
  Okayama University
Cloning, Expression and Identification of Specific Genes related Osseointegration to Titanium.
- Principal Investigator
  
  KANYAMA Manabu
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  補綴理工系歯学
- Research Institution
  OKAYAMA UNIVERSITY
The trial of treatment for temporomandibular joint osteoarthritis with soluble tumor necrosis factor receptor
- Principal Investigator
  
  MAEKAWA Kenji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  補綴理工系歯学
- Research Institution
  OKAYAMA UNIVERSITY
Molecular mechanism of temporomandibular joint osteoarthritis and gene therapy for degraded, cartilagePrincipal Investigator
- Principal Investigator
  
  FUJISAWA Takuo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  補綴理工系歯学
- Research Institution
  OKAYAMA UNIVERSITY
MMP-3転写調節部位遺伝子多型からみた顎関節症の予後に関する分子遺伝学的研究
- Principal Investigator
  
  MINAKUCHI Hajime
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  補綴理工系歯学
- Research Institution
  Okayama University
Gene therapy for temporomandibular joint osteoarthritis
- Principal Investigator
  
  KUBOKI Takuo
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  補綴理工系歯学
- Research Institution
  OKAYAMA UNIVERSITY

All 2010 2006 2005 2004

All Journal Article Presentation

[Journal Article] Possibility of auricular cartilage reconstruction with CCN2/CTGF.2006
- Author(s)
  Fujisawa T et al.
- Journal Title
  
  4^<th> International Workshop on The CCN Family of Genes Program and Abstracts
  
  Pages: 47-47
- Data Source
  KAKENHI-PROJECT-18592121
[Journal Article] Effect of Titanium on the Attachment, Proliferation, Differentiation, and Gene Expression of Osteoblastic Cell Line, MC3T3-E1 cells2006
- Author(s)
  K.AkiyamaV, F.Myokai, T.fujisawa, Y.Yosida, M.Ono, M.Kanyama, S.Takashiba, K.Suzuki, T.Kuboki
- Journal Title
  
  Academy of Osseointegration 21^s^t Annual Meeting Program guide
  
  Pages: 80-80
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390592
[Journal Article] Effect of Titanium on the Attachment, Proliferation, Differentiation, and Gene Expression of Osteoblastic Cell Line, MC3T3-E1 cells.2006
- Author(s)
  K.Akiyama, F.Myokai, T.Fujisawa, Y.Yosida, M.Ono, M.Kanyama, S.Takashiba, K.Suzuki, T.Kuboki
- Journal Title
  
  Academy of Osseointegration 21^<st> Annual Meeting Program Guide 80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390592
[Journal Article] 結合組織成長因子CCN2/CTGFによる骨髄由来間質細胞の細胞接着,遊走の促進2006
- Author(s)
  大野充昭, 藤澤拓生他
- Journal Title
  
  第五回日本再生医療学会抄録集 Vol 5 Supl
  
  Pages: 137-137
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] Connective tissue growth factor (CCN2/CTGF) enhanced hBMSC attachment and migration.2006
- Author(s)
  Ono M, Fujisawa T, Kuboki T et al.
- Journal Title
  
  Regenerative Medicine vol 5 suppl
  
  Pages: 137-137
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] Initial cell attachment, proliferation and differentiation of osteoblast like (MC3T3-Ei) cells to titanium and chrome2005
- Author(s)
  Akiyama K, Fujisawa T, Ono M, Yoshida Y, Kanyama M, Suzuki K, Kuboki T
- Journal Title
  
  The 1^<st> Congress of Asian Academy of Osseointegration Program and Abstract
  
  Pages: 87-87
- Data Source
  KAKENHI-PROJECT-15390592
[Journal Article] 結合組織成長因子CCN2/CTGFによる骨髄由来間質細胞の細胞接着,遊走の促進2005
- Author(s)
  大野充昭, 藤澤拓生他
- Journal Title
  
  第五回日本再生医療学会抄録集 Vol 15 Supl
  
  Pages: 137-137
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] Connective tissue growth factor (CCN2/CTGF) enhanced hBMSC attachment in vitro and migration and survival of the cells in a hydroxyapatite scaffold in vivo.2005
- Author(s)
  Ono M, Fujisawa T et al.
- Journal Title
  
  The 1st Asian Academy of Osseointegration
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] Initial cell attachment, proliferation and differentiation of osteoblast like(MC3T3-Ei) cells to titanium chrome2005
- Author(s)
  Akiyama K, Fujisawa T, Ono M, Yoshida Y, kanyama M, Suzuki K, KUboki T
- Journal Title
  
  The 1^s^t Congress of Asian Academy of Osseointegration Program and Abstract
  
  Pages: 87-87
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390592
[Journal Article] CTGF coating enhanced human bone marrow stromal cell attachment in vitro.2005
- Author(s)
  Ono M, Fujisawa T, Kuboki T et al.
- Journal Title
  
  The 23rd Annual Meeting of the Japanese Society for Bone and Mineral Research, Program and Abstracts
  
  Pages: 225-225
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] 骨芽細胞様細胞株(MC3T3E1)細胞の細胞接着・増殖・分化および遺伝子発現に対するチタンの影響2005
- Author(s)
  秋山謙太郎, 藤沢拓生, 明貝文夫, 完山学, 古田靖弘, 高柴正悟, 鈴木一臣, 窪木拓男
- Journal Title
  
  第35回(社)日本口腔インプラント学会総会・学術大会プログラム・抄録集
  
  Pages: 85-85
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390592
[Journal Article] Connective tissue growth factor (CCN2/CTGF) enhanced hBMSC attachment in vitro and migration and survival of the cells in a hydroxyapatite scaffold in vivo.2005
- Author(s)
  Ono M, Fujisawa T, Kuboki T et al.
- Journal Title
  
  The 1st Asian Academy of Osseointegration
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] Connective, tissue growth factor (CTGF/CCN2) enhanced human bone marrow stromal cell attachment in vitro and migration and survival of the cells in a hydroxyapatite scaffold in vivo.2005
- Author(s)
  Ono M, Fujisawa T, Kuboki T et al.
- Journal Title
  
  J Bone and Mineral Research 20 supl 1
  
  Pages: 203-203
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] Effect of Titanium on the Attachment, Proliferation, Differentiation, and Gene Expression of Osteoblastic Cell Line, MC3T3-E1 cells.2005
- Author(s)
  K.Akiyama, F.Myokai, T.Fujisawa, Y.Yosida, M.Ono, M.Kanyama, S.Takashiba, K.Suzuki, T.Kuboki
- Journal Title
  
  The Japanese Society of Implantrogy 35^<th> Meeting Special Issue 85
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390592
[Journal Article] hBMSC attachment was enhanced by CTGF adsorption in vitro.2005
- Author(s)
  Ono M, Fujisawa T, Kuboki T et al.
- Journal Title
  
  Journal of Dental Research 84 Special issue A
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] hBMSC attachment was enhanced by CTGF adsorption in vitro.2005
- Author(s)
  Ono M, Fujisawa T, Kuboki T et al.
- Journal Title
  
  Journal of Dental Research special issue A
  
  Pages: 84-84
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] 結合組織成長因子CCN2/CTGF/Hcs24はヒト骨髄由来間質細胞の細胞接着を促進させる2005
- Author(s)
  大野充昭, 藤澤拓生他
- Journal Title
  
  日本骨代謝学会誌第23回抄録集
  
  Pages: 225-225
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] Connective tissue growth factor (CCN2/CTGF) enhanced hBMSC attach went in vitro and migration and survival of the cells in a hydrox yapatite scaffold in vivo.2005
- Author(s)
  Ono M, Fujisawa T et al.
- Journal Title
  
  The 1st Asian Academy of Osseointegration
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] Connective tissue growth factor (CTGF/CCN2) enhanced human bone marrow stromal cell attachment in vitro and migration and survival of the cells in hydroxyapatite scaffold in vivo.2005
- Author(s)
  Ono M, Fujisawa T et al.
- Journal Title
  
  J Bone and Mineral Research Vol 20, Supl 1
  
  Pages: 203-203
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] Effect of titanium on the attachment, proliferation, differentiation, and gene expression of osteoblast like cells (MC3T3-E1).2005
- Author(s)
  K.Akiyama, T.Fujisawa, F.Myokai, M.Kanyama, Y.Yoshida, S.Takashiba, K.Suzuki, T.Kuboki
- Journal Title
  
  The 1^<st> Congress of Asian Academy of Osseo-integration Program and Abstract 87
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390592
[Journal Article] 骨芽細胞様細胞株(MC3T3E1)細胞の細胞接着・増殖・分化および遺伝子発現に対するチタンの影響2005
- Author(s)
  秋山謙太郎, 藤澤拓生, 明貝文夫, 完山学, 吉田靖弘, 高柴正悟, 鈴木一臣, 窪木拓男
- Journal Title
  
  第35回(社)日本口腔インプラント学会総会・学術大会プログラム・抄録集
  
  Pages: 85-85
- Data Source
  KAKENHI-PROJECT-15390592
[Journal Article] Connective tissue growth factor (CTGF/CCN2) enhanced human bone marrow stromal cell attachment in vitro and migration and survival of the cells in a hydroxyapatite scaffold in vivo.2005
- Author(s)
  Ono M, Fujisawa T et al.
- Journal Title
  
  J Bone and Mineral Research 20 Supl 1
  
  Pages: 203-203
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] CTGF coating enhanced human bone marrow stromal cell attachment in vitro.2004
- Author(s)
  Ono M, Fujisawa T, Kuboki T et al.
- Journal Title
  
  COAST special issue
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] CTGF coating enhanced human bone marrow stromal cell attachment in vitro.2004
- Author(s)
  Ono M, Fujisawa T, Kuboki T et al.
- Journal Title
  
  Conferences on Orthodontic Advances In Science and Technology special issue
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591947
[Journal Article] CTGF coating enhanced human bone marrow stromal cell attachment in vitro.2004
- Author(s)
  Ono M, Fujisawa T, Kuboki T et al.
- Journal Title
  
  Conferences on Orthodontic Advances In Science and Technology Special issue
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591947
[Presentation] Suppression of BMP-2-induced osteogenic differentiation of hBMSCs by TNF-alpha.2010
- Author(s)
  Fujisawa T
- Organizer
  88th General Session & Exhibition of the IADR
- Place of Presentation
  Balcerona
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21890149

1. KUBOKI Takuo (00225195)

# of Collaborated Projects: 11 results

# of Collaborated Products: 17 results
2. TAKIGAWA Masaharu (20112063)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. UEHARA Junji (10379836)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. YATANI Hirofumi (80174530)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KANYAMA Manabu (90294420)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. MINAKUCHI Hajime (30325097)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. ARAKAWA Hikaru (30304314)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. NAKANISHI Tohru (30243463)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MAEKAWA Kenji (20304313)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 服部高子 (00228488)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KASAI Teruo (00335613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NISHIDA Takashi (30322233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SUZUKI Kouji (30304322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
14. NAWACHI Kumiko (10379787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 高柴正悟 (50226768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 園山亘 (40325121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 李起学

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results

FUJISAWA Takuo 藤澤 拓生

Research Projects

Research Products

Co-Researchers

低分子化合物ライブラリーを用いた骨形成過程における新規BMP2活性制御因子の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel method of promoting alveolar bone formation by controlling the expression of BMP antagonist.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

結合組織成長因子(CCN2/CTGF)を用いた顎顔面領域の三次元軟骨再生Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Bone regeneration with degradable hydrogels and genetically modified, recombinant human BMP-2 with two additional repeats of the heparin-binding domain.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The practice of anti-cytokine treatment for temporomandibular joint osteoarthritis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of an autologous cell transplantion method using mesenchymal stem cells for alveolus bone regeneration.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

口腔インプラントの骨結合獲得難易度を予測する生物学的診断法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cloning, Expression and Identification of Specific Genes related Osseointegration to Titanium.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The trial of treatment for temporomandibular joint osteoarthritis with soluble tumor necrosis factor receptor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of temporomandibular joint osteoarthritis and gene therapy for degraded, cartilagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MMP-3転写調節部位遺伝子多型からみた顎関節症の予後に関する分子遺伝学的研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene therapy for temporomandibular joint osteoarthritis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Possibility of auricular cartilage reconstruction with CCN2/CTGF.2006

Author(s)

Journal Title

Data Source

FUJISAWA Takuo 藤澤拓生