INUAKI Kouichi 犬飼浩一

… Alternative Names

INUKAI Kouichi 犬飼浩一

犬飼浩一イヌカイコウイチ

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Researcher Number	20333007
Affiliation (based on the past Project Information) *help	2012 – 2015: 杏林大学, 医学部, 准教授 2011: 杏林大学, 大学院・医学研究科, 准教授 2007: Saitama Medical University, Faculty of Medicine, Associated Professor 2006: 埼玉医科大学, 医学部, 講師 2001 – 2002: 埼玉医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Metabolomics / Applied health science / Metabolomics Except Principal Investigator Metabolomics / Applied health science
Keywords	Principal Investigator IRS-1 / PI-3キナーゼ / PI-3 kinase / skeletal muscle / NFkappaB / ferritin heavy chain(FHC) / adiponectin / AMPK / LKB1 / PI3-キナーゼ … More / 筋肉 / NFκB / フェリチン / アディポネクチン / インスリン抵抗性 / SCD1 / FGF21 / 肥満 / 糖質制限食 / PPARγ / インスリン感受性 / EBP / C … More Except Principal Investigator VEGF / MCP-1 / 脂肪細胞 / 膵β細胞 / マクロファージ / 2型糖尿病 / PI3K依存性経路 / 脂肪脂肪 / ２型糖尿病 / JNK経路 / Astaxanthin / 内因性酸化ストレス / アンカップリング / 酸化ストレス / インスリン分泌 / 熱ショック蛋白 / サイトカイン / 膵ラ氏島 / フディポカイン / アディポカイン / 糖代謝 / 脂質代謝 / 高圧酸素療法 / 生活習慣病 Less

糖質制限食に対する生体反応～糖尿病モデルマウスを用いた遺伝子学的検索～Principal Investigator
- Principal Investigator
  
  犬飼浩一
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Kyorin University
Elucidation of molecular mechanisms on macrophage infiltration into pancreatic islets in type 2 diabetes and challenging trial to establish its preventive strategy.
- Principal Investigator
  
  Ishida Hitoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kyorin University
Elucidation of involved mechanisms for macrophage infiltration into pancreatic islets and of its role on the occurrence of type 2 diabetes.
- Principal Investigator
  
  ISHIDA Hitoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kyorin University
Finding the novel anti-metabolic syndrome treatment by examining the mechanism of improvement for lipid metabolism with hyperbaric oxygen.
- Principal Investigator
  
  HOSAKA Toshio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Saitama Medical University
  The University of Tokushima
The research for adiponectin signaling via adiponectin receptorsPrincipal Investigator
- Principal Investigator
  
  INUKAI Kouichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Saitama Medical University
C/EBP遺伝子のインスリン感受性細胞への導入によるインスリン抵抗性の機序の解明Principal Investigator
- Principal Investigator
  
  犬飼浩一
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Saitama Medical University

All 2015 2014 2013 2012 2007 Other

All Journal Article Presentation

[Journal Article] Ghrelin augments the expressions and secretions of proinflammatory adipokines, VEGF120 and MCP-1, in differentiated 3T3-L1 adipocytes.2015
- Author(s)
  A. Kitahara, K. Takahashi, R. Moriya, H. Onuma, K. Handa, Y. Sumitani, T. Tanaka, H. Katsuta, S. Nishida, T. Sakurai, K. Inukai, H. Ohno, and H. Ishida.
- Journal Title
  
  J Cell Physiol
  
  Volume: 230 Issue: 1 Pages: 199-209
- DOI
  10.1002/jcp.24699
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461363, KAKENHI-PROJECT-15K01626
[Journal Article] Long-term low carbohydrate diet leads to deleterious metabolic manifestations in diabetic mice.2014
- Author(s)
  Handa K, Inukai K, Onuma H, Kudo A, Nakagawa F, Tsuruga K, Kitahara A, Moriya R, Takahashi K, Sumitani Y, Hosaka T, Kawakami H, Oyadomari S, Ishida H
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 8 Pages: 104948-104948
- DOI
  10.1371/journal.pone.0104948
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25350898, KAKENHI-PROJECT-25461363, KAKENHI-PROJECT-26670270
[Journal Article] Possible involvement of PI3K-dependent pathways in the increased VEGF120 release from osteoblastic cells preloaded with palmitate.2014
- Author(s)
  R. Moriya, K. Takahashi, A. Kitahara, H. Onuma, K. Handa, Y. Sumitani, T. Tanaka, H.Katsuta, S. Nishida, E. Itagaki, K. Inukai, and H. Ishida.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 445 Issue: 2 Pages: 275-281
- DOI
  10.1016/j.bbrc.2014.01.120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461363
[Journal Article] Effects of long-term monotherapy with glimepiride vs glibenclamide on glycemic control and macrovascular events in Japanese type 2 diabetic patients.2014
- Author(s)
  H.Onuma, K.Inukai, M.Watanabe, Y.Sumitani, T.Hosaka, and H.Ishida.
- Journal Title
  
  J Diabetes Mellitus
  
  Volume: 4(1) Issue: 01 Pages: 33-37
- DOI
  10.4236/jdm.2014.41006
- Data Source
  KAKENHI-PROJECT-25461363
[Presentation] 2型糖尿病における骨代謝異常の増悪・進展機構の解明とそれに対する温熱処理の影響の解析．2015
- Author(s)
  高橋和人，森谷理恵，北原敦子，半田桂子，小沼裕寿，炭谷由計，田中利明，勝田秀紀，西田進，近藤琢磨，保坂利男，犬飼浩一，石田均
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25461363
[Presentation] パルミチン酸負荷による骨芽細胞からのVEGF120分泌増大にはPI3K依存性の経路が関与している可能性がある．2015
- Author(s)
  森谷理恵，高橋和人，北原敦子，炭谷由計，小沼裕寿，田中利明，勝田秀紀，西田進，近藤琢磨，保坂利男，犬飼浩一，石田均
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25461363
[Presentation] 膵β細胞の酸化ストレス下におけるオートファジー機構の意義とアスタキサンチンの保護作用の検討．2015
- Author(s)
  北原敦子，近藤琢磨，高橋和人，村嶋俊隆，森田奈瑠，小沼裕寿，炭谷由計，田中利明，勝田秀紀，保坂利男，犬飼浩一，石田均
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25461363
[Presentation] 2型糖尿病治療別にみるプロインスリンプロセシング機構の回復．2015
- Author(s)
  勝田秀紀，近藤琢磨，石本麻衣，森田奈瑠，村嶋俊隆，小沼裕寿，森谷理恵，高橋和人，田中利明，鈴木清，保坂利男，犬飼浩一，石田均
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25461363
[Presentation] 肥大化脂肪細胞からの完全分泌型VEGF120の低酸素非依存的分泌制御機構の解明2013
- Author(s)
  高橋和人，北原敦子，森谷理恵，五林可織，半田桂子，小沼裕寿，炭谷由計，田中利明，勝田秀紀，西田進，犬飼浩一，石田均
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25461363
[Presentation] 飽和脂肪酸が及ぼす骨芽細胞機能への影響とその分子機構の解析2013
- Author(s)
  森谷理恵，高橋和人，北原敦子，五林可織，半田桂子，小沼裕寿，炭谷由計，田中利明，勝田秀紀，西田進，板垣英二，犬飼浩一，石田均
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25461363
[Presentation] グレリンによる脂肪細胞からのアディポカイン分泌制御機構―MCP-1ならびにVEGF120分泌の促進作用とその分子機構の解明―2013
- Author(s)
  北原敦子，高橋和人，五林可織，半田桂子，森谷理恵，小沼裕寿，炭谷由計，田中利明，勝田秀紀，西田進，板垣英二，犬飼浩一，石田均
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25461363
[Presentation] 脂肪細胞からの炎症関連アディポカイン分泌における温熱処理の影響とその意義.2012
- Author(s)
  高橋和人,北原敦子,森谷理恵,五林可織,半田桂子,小沼裕寿,炭谷由計,田中利明,勝田秀紀,西田進,犬飼浩一,石田均
- Organizer
  第33回日本肥満学会
- Place of Presentation
  京都
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PROJECT-22590993
[Presentation] Adiponectin up-regulates Ferritin Heavy Chain via NFk-B dependent pathway in primary skeletal muscle cells2007
- Author(s)
  Ikegami, Y, Inukai, K, Imai, K, Nakashima, Y, Awata, T, Katayama, S
- Organizer
  American Diabetes Association
- Place of Presentation
  Chicago, International Conference
- Year and Date
  2007-06-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591001
[Presentation] 膵β細胞保護効果に対するアスタキサンチンの細胞内作用機構に関する検討―ケモカインのMCP-1の分泌動態への影響―．
- Author(s)
  北原敦子，高橋和人，森谷理恵，小沼裕寿，半田桂子，森田奈瑠，石本麻衣，炭谷由計，田中利明，勝田秀紀，西田進，犬飼浩一，石田均
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25461363
[Presentation] Direct action of ghrelin enhance the secretions of proinflammatory adipokines from mature 3T3-L1 adipcocytes in vitro.
- Author(s)
  Kitahara A, Takahashi K, Moriya R, Onuma H, Handa K, Sumitani Y, Tanaka T, Katsuta H, Nishida S, Sakurai T, Inukai K, Ohno H, Ishida H
- Organizer
  The American Diabetes Association's 73nd Scientific Sessions,
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-06-13 – 2014-06-17
- Data Source
  KAKENHI-PROJECT-25461363
[Presentation] VEGF120 secretion from palmitate-preloaded osteoblastic cells is enhanced through the activation of PI3K-dependent pathways.
- Author(s)
  Moriya R, Takahashi K, Kitahara A, Onuma H, Handa K, Sumitani Y, Tanaka T, Katsuta H, Nishida S, Itagaki E, Inukai K, Ishida H
- Organizer
  The American Diabetes Association's 73nd Scientific Sessions,
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-06-13 – 2014-06-17
- Data Source
  KAKENHI-PROJECT-25461363
[Presentation] 糖尿病モデルマウスにおける長期糖質制限食投与の影響に関する遺伝子学的検討
- Author(s)
  犬飼浩一、半田桂子、小沼裕寿、炭谷由計、保坂利男、北原敦子、森谷理恵、高橋和人、田中利明、勝田秀紀、西田進、板垣英二、石田均
- Organizer
  第57回日本糖尿病学会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-25350898
[Presentation] 骨芽細胞からのサイトカイン分泌に及ぼす飽和脂肪酸の影響とその細胞内シグナル伝達経路に関する検討
- Author(s)
  森田理恵，高橋和人，北原敦子，小沼裕寿，半田桂子，炭谷由計，田中利明，勝田秀紀，西田進，板垣英二，犬飼浩一，石田均
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25461363
[Presentation] 糖尿病での骨代謝異常における基盤病態の解明とそれに対する温熱処理の影響の検討．
- Author(s)
  高橋和人，森田理恵，北原敦子，半田桂子，小沼裕寿，村嶋俊隆，炭谷由計，田中利明，勝田秀紀，西田進，犬飼浩一，石田均
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25461363

1. ISHIDA Hitoshi (80212893)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
2. HOSAKA Toshio (60403698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. NAKAYA Yutaka (50136222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NAGAMATSU Shinya (80231489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YOSHIMOTO Katsuhiko (20271257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. AWATA Takuya (40184303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

INUAKI Kouichi 犬飼 浩一

INUKAI Kouichi 犬飼 浩一

犬飼 浩一 イヌカイ コウイチ

Research Projects

Research Products

Co-Researchers

糖質制限食に対する生体反応～糖尿病モデルマウスを用いた遺伝子学的検索～Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of molecular mechanisms on macrophage infiltration into pancreatic islets in type 2 diabetes and challenging trial to establish its preventive strategy.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of involved mechanisms for macrophage infiltration into pancreatic islets and of its role on the occurrence of type 2 diabetes.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Finding the novel anti-metabolic syndrome treatment by examining the mechanism of improvement for lipid metabolism with hyperbaric oxygen.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The research for adiponectin signaling via adiponectin receptorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

C/EBP遺伝子のインスリン感受性細胞への導入によるインスリン抵抗性の機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Ghrelin augments the expressions and secretions of proinflammatory adipokines, VEGF120 and MCP-1, in differentiated 3T3-L1 adipocytes.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-term low carbohydrate diet leads to deleterious metabolic manifestations in diabetic mice.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Possible involvement of PI3K-dependent pathways in the increased VEGF120 release from osteoblastic cells preloaded with palmitate.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of long-term monotherapy with glimepiride vs glibenclamide on glycemic control and macrovascular events in Japanese type 2 diabetic patients.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 2型糖尿病における骨代謝異常の増悪・進展機構の解明とそれに対する温熱処理の影響の解析．2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] パルミチン酸負荷による骨芽細胞からのVEGF120分泌増大にはPI3K依存性の経路が関与している可能性がある．2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 膵β細胞の酸化ストレス下におけるオートファジー機構の意義とアスタキサンチンの保護作用の検討．2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

INUAKI Kouichi 犬飼浩一

INUKAI Kouichi 犬飼浩一

犬飼浩一イヌカイコウイチ