MASUI Shinji 升井伸治

… Alternative Names

升井伸治マスイシンジ

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Researcher Number	20342850
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2023: 山梨大学, 大学院総合研究部, 特任准教授 2018 – 2021: 山梨大学, 大学院総合研究部, 特任准教授 2018 – 2019: 京都府立医科大学, 医学(系)研究科(研究院), 特任准教授 2016 – 2017: 京都大学, iPS細胞研究所, 特定拠点講師 2013 – 2014: 京都大学, iPS細胞研究所, 講師 … More 2012: 京都大学, ｉＰＳ細胞研究所, 講師 2010: 独立行政法人国立国際医療研究センター, 細胞組織再生医学研究部形質転換ベクター開発研究室, 室長 2009: 国立国際医療センター(研究所) 2009: Research Institute, International Medical Center of Japan, 細胞組織再生医学研究部・形質転換ベクター開発研究室, 室長 2008: Research Institute, International Medical Center of Japan, 細胞組織再生医学研究部形質転換ベクター開発研究室, 室長 2008: 国立国際医療センター, その他の部局等, 室長 2006: 国立国際医療センター(研究所), 細胞組織再生医学研究部, 室長 2003 – 2005: 独立行政法人理化学研究所, 多能性幹細胞研究チーム, 研究員 2002: 理化学研究所, 多能性幹細胞研究チーム, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 27040:Biofunction and bioprocess engineering-related / Regenerative medicine / General medical chemistry / Biological Sciences / Molecular biology / Molecular biology Except Principal Investigator Biological Sciences / Basic Section 56020:Orthopedics-related / Basic Section 59040:Nutrition science and health science-related / Orthopaedic surgery / Medium-sized Section 57:Oral science and related fields
Keywords	Principal Investigator 転写因子 / ES細胞 / 細胞分化 / iPS細胞 / 神経幹細胞 / Sox2 / テトラサイクリン / ROSA26 / NEDD4 / 4 … More / Oct-3 / シグナル伝達 / 分子ネットワーク / 分子経路 / ダイレクトリプログラミング / 初期化 / コアネットワーク / ポリコーム / マスター転写因子 / 肝幹細胞 / 自己複製 / 栄養膜幹細胞 / Es細胞 / Oct3 / 胚体外内胚葉 / 栄養外胚葉 / GATA-6 / TAP / 分化 … More Except Principal Investigator 凍結保存 / 再生医学 / 椎間板 / 腰痛 / 椎間板再生 / 髄核細胞 / 再生医療 / 転写因子 / 幹細胞 / 多能性 / ES細胞 / 培養法 / リプログラミング / 細胞移植 / 脳 / 食 / 生活習慣 / 認知機能 / オミックス解析 / エピゲノム / バイオバンク / 健康長寿 / 創薬 / iPS細胞技術 / 脊椎脊髄病学 / 整形外科学 / 同種細胞移植 / 移植・再生医療 / iPS細胞 / インシリコ創薬 / iPS技術 / 椎間板変性 / ステムセルエイジング / 間葉系幹細胞 / iPS干渉法 / iPS干渉 / 老化 / p53 / Nucleostemin / アポトーシス / 細胞分化 / ノックアウト / 子宮内胎児発育遅延 / 胎盤 / 細胞増殖 / UTF1 / Nanog / 未分化性 / Oct-3 / 初期化 / 栄養外胚葉 / Cdx2 / 4 / Oct3 / Klf4 / Sox2 Less

A proposal for "anti-dementia dietary habits" based on healthy longevity epigenomics that links dietary habits and cognitive function
- Principal Investigator
  
  田中佑治
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  University of Yamanashi
Basic development for reprogramming methods and translation of regenerative medicine in intervertebral disc cells
- Principal Investigator
  
  Sakai Daisuke
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Tokai University
細胞非自律的に作用する遺伝子の網羅的同定法開発Principal Investigator
- Principal Investigator
  
  升井伸治
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  University of Yamanashi
Elucidation of undifferentiated maintaining mechanism of stem cell towards the control of stem cell aging
- Principal Investigator
  
  Kuboki Takuo
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Okayama University
Intervertebral disc regeneration and transcriptional control of nucleus pulpous progenitor cells by in silico pharmacogenesis and iPS technology
- Principal Investigator
  
  SAKAI Daisuke
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokai University
Molecular mechanism of interference with iPSC inductionPrincipal Investigator
- Principal Investigator
  
  MASUI Shinji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Regenerative medicine
- Research Institution
  Kyoto University
多因子発現系を用いた迅速分化誘導法の開発Principal Investigator
- Principal Investigator
  
  升井伸治
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Research Institute, International Medical Center of Japan
幹細胞における無限自己複製の制御機構Principal Investigator
- Principal Investigator
  
  升井伸治
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Research Institute, International Medical Center of Japan
ES細胞特有の細胞増殖調節におけるUTF1遺伝子の役割
- Principal Investigator
  
  奥田晶彦
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Saitama Medical University
転写因子Oct-3/4の新規コファクター単離ならびに機能解析Principal Investigator
- Principal Investigator
  
  升井伸治
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  The Institute of Physical and Chemical Research
転写制御から見た体細胞初期化機構の解析
- Principal Investigator
  
  丹羽仁史
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
転写因子Oct-3/4と相互作用する新規コファクターの探索ならびに機能解析Principal Investigator
- Principal Investigator
  
  升井伸治
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  The Institute of Physical and Chemical Research

All 2022 2020 2019 2014 2013 2011 2010 2009 2008 2005

All Journal Article Presentation Patent

[Journal Article] Optimized conditions for the supplementation of human-induced pluripotent stem cell cultures with a GSK-3 inhibitor during embryoid body formation with the aim of inducing differentiation into mesodermal and cardiac lineage2020
- Author(s)
  Yoda Kiyomi、Ohnuki Yoshitsugu、Masui Shinji、Kurosawa Hiroshi
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 129 Issue: 3 Pages: 371-378
- DOI
  10.1016/j.jbiosc.2019.09.015
- NAID
  40022194562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05169
[Journal Article] Direct Reprogramming Into Corneal Epithelial Cells Using a Transcriptional Network Comprising PAX6, OVOL2, and KLF42019
- Author(s)
  Kitazawa Koji、Hikichi Takafusa、Nakamura Takahiro、Nakamura Masahiro、Sotozono Chie、Masui Shinji、Kinoshita Shigeru
- Journal Title
  
  Cornea
  
  Volume: 38 Issue: 1 Pages: S34-S41
- DOI
  10.1097/ico.0000000000002074
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05169, KAKENHI-PROJECT-19H03809, KAKENHI-PROJECT-17K11487, KAKENHI-PROJECT-18K16930
[Journal Article] Transcription factors interfering with dedifferentiation induce cell type-specific transcriptional profiles.2013
- Author(s)
  Hikichi T, Matoba R, Ikeda T, Watanabe A, Yamamoto T, Yoshitake S, Tamura-Nakano M, Kimura T, Kamon M, Shimura M, Kawakami K, Okuda A, Okochi H, Inoue T, Suzuki A, Masui S.
- Journal Title
  
  Proceeding of the National Academy of Sciences of USA
  
  Volume: 110 Issue: 16 Pages: 6412-6417
- DOI
  10.1073/pnas.1220200110
- NAID
  120005244176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590275, KAKENHI-PLANNED-23112002, KAKENHI-PROJECT-23241063, KAKENHI-PROJECT-23659840, KAKENHI-PROJECT-24615004, KAKENHI-PROJECT-25293082, KAKENHI-PROJECT-25670146, KAKENHI-PROJECT-25670147, KAKENHI-PROJECT-25713014
[Journal Article] Pluripotency maintenance mechanism of embryonic stem cells and reprogramming.2010
- Author(s)
  Shinji Masui
- Journal Title
  
  Int J Hematol.
  
  Volume: 91 Pages: 360-372
- NAID
  10026400694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659064
[Journal Article] Pluripotency maintenance mechanism of embryonic stem cells and reprogramming.2010
- Author(s)
  Masui, S
- Journal Title
  
  Int J Hematol 91
  
  Pages: 360-372
- NAID
  10026400694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052032
[Journal Article] Differential requirement for nucleostemin in embryonicstem cell and neural stem cell viability.2009
- Author(s)
  Nomura, J., Maruyama, M., Katano, M., Kato, H., Zhang, J., Masui, S., Mizuno, Y., Okazaki, Y., Nishimoto, M., Okuda, A.
- Journal Title
  
  Stem Cells 27
  
  Pages: 1066-1076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052032
[Journal Article] Consequence of the loss of Sox2 in the developing brain of the mouse.2008
- Author(s)
  Miyagi S, Masui S, Niwa H, Saito T, Shimazaki T, Okano H, Nishimoto M, Muramatsu M, Iwama A, Okuda A.
- Journal Title
  
  FEBS Lett. 582
  
  Pages: 2811-2815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052032
[Journal Article] Rexl/Zfp42 is dispensable for pluripotency in mouse ES cells2008
- Author(s)
  Shinji Masui
- Journal Title
  
  BMC Dev. Biol 8
  
  Pages: 45-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20058031
[Journal Article] An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit.2005
- Author(s)
  Masui S, Shimosato D, Toyooka Y, Yagi R, Takahashi K, Niwa H.
- Journal Title
  
  Nucleic Acids Res. 33・4
- Data Source
  KAKENHI-PROJECT-16770137
[Journal Article] An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit.2005
- Author(s)
  Masui, S.
- Journal Title
  
  Nucleic Acids Research 33
- Data Source
  KAKENHI-PROJECT-14081209
[Journal Article] An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit2005
- Author(s)
  Shinji Masui, Daisuke Shimosato, Yayoi Toyooka, Rika Yagi, Kazue Takahashi, Hitoshi Niwa
- Journal Title
  
  Nucleic Acids Research 33(印刷中)
- Data Source
  KAKENHI-PROJECT-16770137
[Patent] 髄核細胞マスターレギュレーター転写因子を含む分化誘導剤、誘導髄核細胞の製造方法、および誘導髄核細胞の用途2022
- Inventor(s)
  酒井大輔、ショール　ジョルディ、平石駿介、升井伸治
- Industrial Property Rights Holder
  学校法人東海大学、国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-502340
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20H03809
[Patent] 髄核細胞マスターレギュレーター転写因子を含む分化誘導剤、誘導髄核細胞の製造方法、および誘導髄核細胞の用途2019
- Inventor(s)
  酒井大輔、ジルディショール、平石駿介、升井伸治
- Industrial Property Rights Holder
  学校法人東海大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-066535
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H05456
[Patent] 髄核マスターレギュレーター転写因子を含む分化転換剤、誘導髄核細胞の製造方法、および誘導髄核細胞の用途2019
- Inventor(s)
  酒井大輔、ジョルディショール、平石駿介、升井伸治
- Industrial Property Rights Holder
  酒井大輔、ジョルディショール、平石駿介、升井伸治
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-066535
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H05456
[Patent] 任意細胞の樹立法開発2009
- Inventor(s)
  升井伸治・引地貴亮
- Industrial Property Rights Holder
  ヒューマンサイエンス財団
- Industrial Property Number
  2009-237407
- Filing Date
  2009-10-14
- Data Source
  KAKENHI-PROJECT-20052032
[Patent] 特許2008
- Inventor(s)
  升井伸治, 大河内仁志, 浜崎辰夫
- Industrial Property Rights Holder
  財団法人ヒューマンサイエンス振興財団
- Industrial Property Number
  2008-260553
- Filing Date
  2008-10-07
- Data Source
  KAKENHI-PROJECT-20052032
[Presentation] Screening of molecules that facilitate transition from mouse embryonic stem cells to early-embryonic-like cells2020
- Author(s)
  Aoi Murakami, Yoshitsugu Ohnuki, Shinji Masui, Hiroshi Kurosawa
- Organizer
  JAACT2020 Fuchu
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05169
[Presentation] Primitive endoderm cells promote proliferation and differentiation of pluripotent stem cells2020
- Author(s)
  Takumi Iwama, Yoshitsugu Ohnuki, Shinji Masui, Hiroshi Kurosawa
- Organizer
  JAACT2020 Fuchu
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05169
[Presentation] 細胞らしさの制御メカニズム　多能性幹細胞と体細胞2020
- Author(s)
  升井伸治
- Organizer
  第19回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K05169
[Presentation] Novel Cyclic N-alkyl Peptides as BFGF Mimetics to Maintain the Pluripotency of Human Induced Pluripotent Stem Cells2020
- Author(s)
  Masashi Sato, Hiromi Tanaka, Yoshitsugu Ohnuki, Shinji Masui, Takashi Kawakami, Hiroshi Kurosawa
- Organizer
  JAACT2020 Fuchu
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05169
[Presentation] ヒトiPS細胞の未分化増殖を可能にする新規ペプチド化合物の分子進化工学的スクリーニング法による探索及び人工 FGFRアゴニストとしての機能解析2019
- Author(s)
  佐藤将、大貫喜嗣、升井伸治、川上隆史、黒澤尋
- Organizer
  第71回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19K05169
[Presentation] ヒトiPS細胞において中胚葉分化が促進された胚様体を形成するためのGSK-3β阻害剤処理条件の検討2019
- Author(s)
  依田聖未、大貫喜嗣、升井伸治、黒澤尋
- Organizer
  日本組織培養学会第92回大会
- Data Source
  KAKENHI-PROJECT-19K05169
[Presentation] 初期化を阻害する因子が分化を促進する2014
- Author(s)
  升井　伸治
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館、京都市
- Invited
- Data Source
  KAKENHI-PROJECT-24615004
[Presentation] Transcription factors interfering with dedifferentiation induce cell type-specific transcriptional profiles2014
- Author(s)
  Masui S
- Organizer
  47th Annual Meeting for the Japanese Society of Developmental Biologists (JSDB) cosponsored by the Asia-Pacific Developmental Biology Network (APDBN)
- Place of Presentation
  名古屋市
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PROJECT-24615004
[Presentation] Transcription factors interfering with dedifferentiation induce cell type-specific transcriptional profiles2013
- Author(s)
  Shinji Masui
- Organizer
  ISSCR 10th annual meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24615004
[Presentation] 初期化を阻害する因子が分化を促進する2013
- Author(s)
  升井　伸治
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド、神戸市
- Data Source
  KAKENHI-PROJECT-24615004
[Presentation] Systematic Identification of Transcription Factors Capable of Inducing Cells of Interest2011
- Author(s)
  升井伸治
- Organizer
  CDB symposium 2011
- Place of Presentation
  理化学研究所CDB, 神戸市
- Year and Date
  2011-03-14
- Data Source
  KAKENHI-PROJECT-22659064
[Presentation] Functional analysis of Sox2 in differentiation of extra-embrvonic endoderm lineages2008
- Author(s)
  升井伸治
- Organizer
  2nd International SOX meeting (2008)
- Place of Presentation
  淡路島、兵庫県
- Year and Date
  2008-09-16
- Data Source
  KAKENHI-PROJECT-20052032

1. SAKAI Daisuke (10408007)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. Kuboki Takuo (00225195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 丹羽仁史 (80253730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山中伸弥 (10295694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 中尾和貴 (20217657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 奥田晶彦 (60201993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 丸山昌良 (10423055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 大野充昭 (60613156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 宝田剛志 (30377428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 渡辺亮 (60506765)

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11. 大野彩 (20584626)

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12. 秋山謙太郎 (70423291)

# of Collaborated Projects: 1 results

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13. 檜山明彦 (00514382)

# of Collaborated Projects: 1 results

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14. 平山令明 (70238393)

# of Collaborated Projects: 1 results

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15. 黒澤尋 (10225295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
16. 斉藤美佳子 (20291346)

# of Collaborated Projects: 1 results

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17. 若山照彦 (40360672)

# of Collaborated Projects: 1 results

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18. 田中佑治 (40625513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 池尾一穂 (20249949)

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20. 麦倉俊司 (20375017)

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21. 幸田尚 (60211893)

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22. 望月和樹 (80423838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MASUI Shinji 升井 伸治

升井 伸治 マスイ シンジ

Research Projects

Research Products

Co-Researchers

A proposal for "anti-dementia dietary habits" based on healthy longevity epigenomics that links dietary habits and cognitive function

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic development for reprogramming methods and translation of regenerative medicine in intervertebral disc cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞非自律的に作用する遺伝子の網羅的同定法開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of undifferentiated maintaining mechanism of stem cell towards the control of stem cell aging

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Intervertebral disc regeneration and transcriptional control of nucleus pulpous progenitor cells by in silico pharmacogenesis and iPS technology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of interference with iPSC inductionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

多因子発現系を用いた迅速分化誘導法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

幹細胞における無限自己複製の制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ES細胞特有の細胞増殖調節におけるUTF1遺伝子の役割

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

転写因子Oct-3/4の新規コファクター単離ならびに機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

転写制御から見た体細胞初期化機構の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

転写因子Oct-3/4と相互作用する新規コファクターの探索ならびに機能解析Principal Investigator

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[Journal Article] Optimized conditions for the supplementation of human-induced pluripotent stem cell cultures with a GSK-3 inhibitor during embryoid body formation with the aim of inducing differentiation into mesodermal and cardiac lineage2020

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MASUI Shinji 升井伸治

升井伸治マスイシンジ