FUJIO Yasushi 藤尾慈

Researcher Number	20359839
Other IDs	https://orcid.org/0000-0003-0828-2930
Affiliation (Current)	2025: 大阪大学, 大学院薬学研究科, 教授
Affiliation (based on the past Project Information) *help	2025: 大阪大学, 大学院薬学研究科, 教授 2022 – 2023: 大阪大学, 大学院薬学研究科, 教授 2016 – 2021: 大阪大学, 薬学研究科, 教授 2011 – 2016: 大阪大学, 薬学研究科(研究院), 教授 2014: 大阪大学, 大学院薬学研究科, 教授 … More 2013: 大阪大学, 薬学研究科, 教授 2009 – 2012: 大阪大学, 大学院・薬学研究科, 教授 2009 – 2011: Osaka University, 薬学研究科, 教授 2008: 大阪大学, 大学院・薬学研究科, 准教授 2007 – 2008: Osaka University, Graduate School of Pharmacuetical Sciences, Associate Professor 2004 – 2006: 大阪大学, 薬学研究科, 助教授 2004: 大阪大学, 大学院・薬学研究科, 助教授 Less
Review Section/Research Field	Principal Investigator General pharmacology / Basic Section 48030:Pharmacology-related / Medium-sized Section 52:General internal medicine and related fields / Medium-sized Section 53:Organ-based internal medicine and related fields / Experimental pathology Except Principal Investigator Circulatory organs internal medicine / Basic Section 47060:Clinical pharmacy-related / General pharmacology / Medical pharmacy / Medium-sized Section 47:Pharmaceutical sciences and related fields … More / Biological pharmacy / Cardiovascular surgery / Thoracic surgery / Biological Sciences Less
Keywords	Principal Investigator STAT3 / 心筋細胞増殖 / 心不全 / 心筋細胞 / サイトカイン / 再生 / 心筋 / 心筋組織修復 / 心筋炎 / 炎症 … More / 心血管・血液 / 心臓 / 心筋リモデリング / 組織幹細胞 / 心筋梗塞 / 心筋炎症 / 治療標的 / 再生治療 / 心筋再生 / 二倍体心筋細胞 / 1細胞解析 / Regeneration / Tissue repai / Cytoprotection / Cardiovascular / Signal transduction / Interleukin / 活性酸素 / メタロチオネイン / Wnt / cadherin / IL-11 / 血管発生 / 血管新生 / 分化 / 血管内皮細胞 / 組織修復 / 細胞保護 / 心血管 / シグナル伝達 / IL-6関連サイトカイン / Moesin / 循環器・高血圧 / 細胞骨格 / 組織修復・再生 / 細胞傷害 / 心筋細胞死 / 免疫学的監視機構 / Pim-1 / IL-6 / 血管内皮 / 心筋組織幹細胞 / 細胞運命 … More Except Principal Investigator 血管内皮細胞 / 炎症 / CYP2D6 / SNRI / SSRI / 心筋保護効果 / 心臓血管外科 / IL-11 / STAT3 / 心不全 / 臨床研究 / 心筋梗塞 / 心筋細胞 / 薬剤反応性 / トロンボスポンジン / 血管内皮機能 / 喫煙 / 薬物投与量管理 / 機械学習 / 社会実装 / 投与量予測モデル / ハイリスク薬 / 抗凝固薬 / 線維芽細胞 / ダイレクトリプログラミング / 線維症 / 循環器疾患 / 民族差 / 循環器系疾患 / ゲノム薬理学 / 国際共同研究 / シグナル伝達系 / 炎症性サイトカイン / 免疫細胞 / HDAC阻害剤 / スクリーニング系 / 低分子化合物 / 治療薬 / インターロイキン6 / 単球 / 敗血症 / Robo4 / 心筋リモデリング / LRG / 心筋梗塞後リモデリング / マクロファージ / 血管新生 / リモデリング / Pim-1 / Il-6ファミリーサイトカイン / N-cadherin / Pim-1キナーゼ / 心筋保護シグナル / 虚血性心疾患 / serotonin receptor / serotonin transporter / Fluvoxamine / drug responsiveness / セロトニントランスポーター / セロトニン受容体 / セロトニントランスポータ / フルボキサミン / サイトカイン療法 / ニコチン依存度 / 血管障害 / 禁煙 / 細胞死 / プロテインキナーゼA / カルシウムチャネル / シグナリング / マイクロドメイン / カルモデュリン依存性キナーゼ / 心肥大 / チャネル / カルシウム / 遺伝子改変動物モデル / Signal transducere and activator of transcription 3(STAT3) / 虚血・再灌流傷害 / インターロイキン-11(IL-11) / 虚血・再灌流 / インターロイキン-11 / 虚血再灌流 / シグナル / サイトカイン / 左室収縮能改善 / 血管内皮機能改善 / 拡張型心筋症 / 遺伝子多型 / 左室収縮能 / アドレナリンβ受容体遮断薬 / 慢性心不全 / 内科 / 臨床 / 薬理学 / 循環器・高血圧 / 薬剤応答性 / ニコチン依存 / CYP2A6 / 慢性閉塞性呼吸器疾患 Less

心臓の恒常性維持/組織リモデリングおけるFibrocytesの意義の解明Principal Investigator
- Principal Investigator
  
  藤尾慈
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  The University of Osaka
血管を経由する新発想での臓器の脱線維化技術の開発
- Principal Investigator
  
  岡田欣晃
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Osaka University
抗凝固薬の有効性及び安全性の予測モデル構築のための基盤研究～社会実装を目指して
- Principal Investigator
  
  前田真貴子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Osaka University
Identification and characterization of novel myeloid cells that infiltrate into post-infarct myocardiumPrincipal Investigator
- Principal Investigator
  
  Fujio Yasushi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Osaka University
ゲノム薬理学を応用した国際共同臨床研究推進のための基盤構築
- Principal Investigator
  
  前田真貴子
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Osaka University
Characterization of diploid cardiomyocytes in adult mammalian heartsPrincipal Investigator
- Principal Investigator
  
  Fujio Yasushi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Osaka University
Molecular mechanisms of cell proliferation of adult mammalian cardiomyocytesPrincipal Investigator
- Principal Investigator
  
  Fujio Yasushi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Osaka University
Study of Cardioprotective Signal through STAT3/Pim Kinase
- Principal Investigator
  
  Makiko Maeda
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University
The role of leucine-rich alpha2 glycoprotein in cardiac remodeling
- Principal Investigator
  
  Nakayama Hiroyuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University
The molecular and cellular mechanism of myocardial repair/regenerationPrincipal Investigator
- Principal Investigator
  
  FUJIO Yasushi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University
The effect of interleukin-11 in a donation after circulatory death heart model
- Principal Investigator
  
  KOUNO Hiroki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Chiba University
Novel anti-sepsis strategy targeting the endothelial cell-specific receptor Robo4
- Principal Investigator
  
  Okada Yoshiaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
Immune surveillance is involved in cardiomyocyte death in diseased heartsPrincipal Investigator
- Principal Investigator
  
  FUJIO Yasushi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Osaka University
Myocardial inflammation of heart failure as a novel therapeutic targetPrincipal Investigator
- Principal Investigator
  
  FUJIO Yasushi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University
Regulation of L-type calcium channel by intracellular subunit in cardiac hypertrophy and failure.
- Principal Investigator
  
  NAKAYAMA HIROYUKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Role of thrombospondin and nicotine dependence in vascular damage from smoking
- Principal Investigator
  
  TAKEMOTO Yasuhiko
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka City University
The Cardioprotective Effect Of Interleukin-11 in Cardiac Surgery
- Principal Investigator
  
  KOUNO Hiroki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Chiba University
The study for the effects of Interluekin-11 on cardiac remodeling following recanalization therapy against myocardial infarction.
- Principal Investigator
  
  MAEDA Makiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Hyogo University of Health Sciences
Dynamics of cardiac stem cells in myocardial repair/regeneration and regulation of their cell fate by cytokinesPrincipal Investigator
- Principal Investigator
  
  FUJIO Yasushi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University
Role and mechanism of thrombospondin in response to beta blocker therapy in patients with congestive heart failure
- Principal Investigator
  
  TAKEMOTO Yasuhiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka City University
うつ病個別化治療推進を目的とする薬効ゲノム情報に基づく科学的基盤の構築
- Principal Investigator
  
  AZUMA J
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Osaka University
喫煙による慢性閉塞性呼吸器疾患発症に関する分子疫学的研究
- Principal Investigator
  
  AZUMA Junichi
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Analysis on the biological roles of STAT3 in cardiac protection, repair and regenerationPrincipal Investigator
- Principal Investigator
  
  FUJIO Yasushi
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University

[Book] 循環器内科;IL-11の心血管系における作用2010
- Author(s)
  尾花理徳、前田真貴子、藤尾慈
- Total Pages
  7
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-22590160
[Book] レスポンダーとノンレスポンダー2009
- Author(s)
  藤尾慈
- Publisher
  医薬ジャーナル
- Data Source
  KAKENHI-PROJECT-20590834
[Journal Article] Lower doses of carvedilol in Japanese heart failure patients with reduced ejection fraction could show the potential to be non-inferior to higher doses in US patients: An international collaborative observational study2024
- Author(s)
  Maeda M, Humber D, Hida E, Ohtani T, Wang G, Wu T, Takeda S, Situ JN, Hayashi J, Nonen S, Takeda T, Okamoto H, Hori M, Sakata Y, Fujio Y, Tsunoda SM.
- Journal Title
  
  PLoS One
  
  Volume: 19 (3) Issue: 3 Pages: e0299510-e0299510
- DOI
  10.1371/journal.pone.0299510
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07218, KAKENHI-PROJECT-21K11784
[Journal Article] Yes‐associated protein activation potentiates glycogen synthase kinase‐3 inhibitor‐induced proliferation of neonatal cardiomyocytes and iPS cell‐derived cardiomyocytes2022
- Author(s)
  Kametani Y, Tanaka S, Wada Y, Suzuki S, Umeda A, Nishinaka K, Okada Y, Maeda M, Miyagawa S, Sawa Y, Obana M, Fujio Y.
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 237 Issue: 5 Pages: 2539-2549
- DOI
  10.1002/jcp.30724
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03382, KAKENHI-PROJECT-20K21575
[Journal Article] Vascular Endothelial Growth Factor Receptor Inhibitors Impair Left Ventricular Diastolic Functions2021
- Author(s)
  Haruka Yokoyama, Wataru Shioyama, Takuya Shintani, Shinichiro Maeda, Sachiko Hirobe, Makiko Maeda, Yasushi Sakata, Yasushi Fujio
- Journal Title
  
  Int. Heart J.
  
  Volume: 62 Issue: 6 Pages: 1297-1304
- DOI
  10.1536/ihj.21-307
- NAID
  130008122384
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2021-11-29
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16385, KAKENHI-PROJECT-20K21575
[Journal Article] Title: Gene Transfer by Pyro-Drive Jet Injector is a Novel Therapeutic Approach for Muscle Diseases2021
- Author(s)
  Nakae Takafumi、Obana Masanori、Maeda Takahiro、Ikeda Akari、Miyazaki Hiroshi、Tanaka Shota、Maeda Makiko、Yamashita Kunihiko、Terai Kazuhiro、Obika Satoshi、Fujio Yasushi
- Journal Title
  
  Gene
  
  Volume: in press Pages: 145664-145664
- DOI
  10.1016/j.gene.2021.145664
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02603, KAKENHI-PROJECT-18K15027, KAKENHI-PROJECT-20K21575
[Journal Article] PKNOX2 regulates myofibroblast functions and tubular cell survival during kidney fibrosis2021
- Author(s)
  Miyake Y, Obana M, Nakae T, Yamamoto A, Tanaka S, Maeda M, Okada Y, Fujio Y.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 571 Pages: 88-95
- DOI
  10.1016/j.bbrc.2021.07.067
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21575
[Journal Article] Maresin-1 induces cardiomyocyte hypertrophy through IGF-1 paracrine pathway2021
- Author(s)
  Wahyuni T, Kobayashi A, Tanaka S, Miyake Y, Yamamoto A, Bahtiar A, Mori S, Kametani Y, Tomimatsu M, Matsumoto K, Maeda M, Obana M, Fujio Y.
- Journal Title
  
  American Journal of Physiology-Cell Physiology
  
  Volume: 321 Issue: 1 Pages: C82-C93
- DOI
  10.1152/ajpcell.00568.2020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21575
[Journal Article] Transcription factor old astrocyte specifically induced substance is a novel regulator of kidney fibrosis2020
- Author(s)
  Yamamoto Ayaha、Morioki Hitomi、Nakae Takafumi、Miyake Yoshiaki、Harada Takeo、Noda Shunsuke、Mitsuoka Sayuri、Matsumoto Kotaro、Tomimatsu Masashi、Kanemoto Soshi、Tanaka Shota、Maeda Makiko、Conway Simon J.、Imaizumi Kazunori、Fujio Yasushi、Obana Masanori
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 2
- DOI
  10.1096/fj.202001820r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21575, KAKENHI-PROJECT-20K21578, KAKENHI-PROJECT-18H02603, KAKENHI-PROJECT-18K15027, KAKENHI-PLANNED-17H06416
[Journal Article] Progesterone receptor membrane component 1 leads to erlotinib resistance, initiating crosstalk of Wnt/β-catenin and NF-κB pathways, in lung adenocarcinoma cells2020
- Author(s)
  Lin Y, Higashisaka K, Shintani T, Maki A, Hanamuro S, Haga Y, Maeda S, Tsujino H, Nagano K, Fujio Y, Tsutsumi Y
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 4748-4748
- DOI
  10.1038/s41598-020-61727-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02603, KAKENHI-PROJECT-18J21507, KAKENHI-PROJECT-18K19545, KAKENHI-PROJECT-20K16385
[Journal Article] QT/QTc study shows that a novel 5-HT4 receptor partial agonist minesapride has no effect on QT prolongation.2020
- Author(s)
  Hamatani, T., Noda, N., Takagaki, T., Yodo, Y., Kakuyama, H., Kaji, Y., Fujio, Y.
- Journal Title
  
  Clin. Pharmacol. Drug Develop
  
  Volume: in press Issue: 8 Pages: 938-951
- DOI
  10.1002/cpdd.778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02603, KAKENHI-PROJECT-18K19545
[Journal Article] β2‐adrenergic stimulation induces interleukin‐6 by increasing Arid5a, a stabilizer of mRNA, through cAMP/PKA/CREB pathway in cardiac fibroblasts2020
- Author(s)
  Tanaka Shota、Imaeda Atsuki、Matsumoto Kotaro、Maeda Makiko、Obana Masanori、Fujio Yasushi
- Journal Title
  
  Pharmacology Research & Perspectives
  
  Volume: 8 Issue: 2
- DOI
  10.1002/prp2.590
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19545, KAKENHI-PROJECT-18H02603, KAKENHI-PROJECT-18K15027
[Journal Article] Adenovirus Vector?Induced IL-6 Promotes Leaky Adenoviral Gene Expression, Leading to Acute Hepatotoxicity2020
- Author(s)
  Shimizu Kahori、Sakurai Fuminori、Iizuka Shunsuke、Ono Ryosuke、Tsukamoto Tomohito、Nishimae Fumitaka、Nakamura Shin-ichiro、Nishinaka Toru、Terada Tomoyuki、Fujio Yasushi、Mizuguchi Hiroyuki
- Journal Title
  
  The Journal of Immunology
  
  Volume: 206 Issue: 2 Pages: 410-421
- DOI
  10.4049/jimmunol.2000830
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21575, KAKENHI-PROJECT-17H04101, KAKENHI-PROJECT-18H02603, KAKENHI-PROJECT-18K14964, KAKENHI-PROJECT-20H00664
[Journal Article] The CalcR-PKA-Yap1 Axis Is Critical for Maintaining Quiescence in Muscle Stem Cells.2019
- Author(s)
  Zhang L, Noguchi YT, Nakayama H, Kaji T, Tsujikawa K, Ikemoto-Uezumi M, Uezumi A, Okada Y, Doi T, Watanabe S, Braun T, Fujio Y, Fukada SI.
- Journal Title
  
  Cell Rep
  
  Volume: 19 Issue: 8 Pages: 2154-63
- DOI
  10.1016/j.celrep.2019.10.057
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19740, KAKENHI-PROJECT-19K22496, KAKENHI-PROJECT-18H02603, KAKENHI-PROJECT-19H04000, KAKENHI-PROJECT-18K19545
[Journal Article] Old-Age Onset Progressive Cardiac Contractile Dysfunction in a Patient with Polycystic Kidney Disease Harboring a <i>PKD1</i> Frameshift Mutation2019
- Author(s)
  Suwa Yoshinobu、Higo Shuichiro、Nakamoto Kei、Sera Fusako、Kunimatsu Suzuka、Masumura Yuki、Kanzaki Machiko、Mizote Isamu、Mizuno Hiroya、Fujio Yasushi、Hikoso Shungo、Sakata Yasushi
- Journal Title
  
  Int. Heart J.
  
  Volume: 60 Issue: 1 Pages: 220-225
- DOI
  10.1536/ihj.18-184
- NAID
  130007557187
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2019-01-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19543, KAKENHI-PROJECT-18K19545, KAKENHI-PROJECT-18K15848, KAKENHI-PROJECT-18H02603, KAKENHI-PROJECT-16K09500, KAKENHI-PROJECT-17K16004
[Journal Article] Blockade of NKG2D/NKG2D ligand interaction attenuated cardiac remodeling after myocardial infarction2019
- Author(s)
  Matsumoto, K., Obana, M., Kobayashi, A., Miyagawa, S., Maeda, M., Sakata, Y., Nakayama, H., Sawa, Y., Fujio, Y.
- Journal Title
  
  Cardiovasc. Res.
  
  Volume: 115 Issue: 4 Pages: 765-775
- DOI
  10.1093/cvr/cvy254
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19545, KAKENHI-PROJECT-18H02603
[Journal Article] Myofibroblast β2 adrenergic signaling amplifies cardiac hypertrophy in mice.2019
- Author(s)
  1.Imaeda A, Tanaka S, Tonegawa K, Fuchigami S, Obana M, Maeda M, Kihara M, Kiyonari H, Conway SJ, Fujio Y, Nakayama H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 510 Issue: 1 Pages: 149-155
- DOI
  10.1016/j.bbrc.2019.01.070
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09576, KAKENHI-PROJECT-18K19545, KAKENHI-PROJECT-18H02603
[Journal Article] Caveolae-specific CaMKII signaling in the regulation of voltage-dependent calcium channel and cardiac hypertrophy.2018
- Author(s)
  Tanaka, S., Fujio, Y., Nakayama, H.
- Journal Title
  
  Front. Physiol.
  
  Volume: 9 Pages: 1081-1081
- DOI
  10.3389/fphys.2018.01081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19545, KAKENHI-PROJECT-18H02603
[Journal Article] Eukaryotic translation initiation factor 3 subunit C is associated with acquired resistance to erlotinib in non-small cell lung cancer.2018
- Author(s)
  Shintani, T., Higashisaka, K., Maeda, M., Hamada, M., Tsuji, R., Kurihara, K., Kashiwagi, Y., Sato, A., Obana, M., Yamamoto, A., Kawasaki, K., Lin, Y., Kijima, T., Kinehara, Y., Miwa, Y., Maeda, S., Morii, E., Kumanogoh, A., Tsutsumi, Y., Nagatomo, I., Fujio, Y.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 101 Pages: 37520-37533
- DOI
  10.18632/oncotarget.26494
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19545, KAKENHI-PROJECT-18H02603
[Journal Article] The cardioprotective effect of interleukin-11 against ischemia-reperfusion injury in a heart donor model2018
- Author(s)
  Tamura Yusaku、Kohno Hiroki、Mohri Tomomi、Fujio Yasushi、Matsumiya Goro
- Journal Title
  
  Annals of Cardiothoracic surgery
  
  Volume: 7 Issue: 1 Pages: 99-105
- DOI
  10.21037/acs.2017.09.11
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462082
[Journal Article] The Robo4-TRAF7 complex suppresses endothelial hyperpermeability in inflammation2018
- Author(s)
  Shirakura Keisuke、Ishiba Ryosuke、Kashio Taito、Funatsu Risa、Tanaka Toru、Fukada So-ichiro、Ishimoto Kenji、Hino Nobumasa、Kondoh Masuo、Ago Yukio、Fujio Yasushi、Yano Kiichiro、Doi Takefumi、Aird William C.、Okada Yoshiaki
- Journal Title
  
  Journal of Cell Science
  
  Volume: 132 Pages: 220228-220228
- DOI
  10.1242/jcs.220228
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19403, KAKENHI-PROJECT-17K19487, KAKENHI-PROJECT-18H02603, KAKENHI-PROJECT-18K19545
[Journal Article] Adult murine cardiomyocytes exhibit regenerative activity with cell cycle reentry through STAT3 in the healing process of myocarditis.2017
- Author(s)
  Miyawaki, A., Obana, M., Mitsuhara, Y., Orimoto, A., Nakayasu, Y., Yamashita, T., Fukada, S., Maeda, M., Nakayama, H., Fujio, Y.
- Journal Title
  
  Sci. Rep.
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293054
[Journal Article] Caveolae-specific activation loop between CaMKII and L-type Ca2+ channel aggravates cardiac hypertrophy in α1 adrenergic stimulation.2017
- Author(s)
  Tonegawa, K., Otsuka, W., Kumagai, S., Matsunami, S., Hayamizu, N., Tanaka, S., Moriwaki, K., Obana, M., Maeda, M., Asahi, M., Kiyonari, H., Fujio, Y., Nakayama, H.
- Journal Title
  
  Am. J. Physiol. Heart Circ. Physiol.
  
  Volume: ３１２ Issue: 3 Pages: H501-H514
- DOI
  10.1152/ajpheart.00601.2016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293054, KAKENHI-PROJECT-15K08232
[Journal Article] RORγt-expressing cells attenuate cardiac remodeling after myocardial infarction.2017
- Author(s)
  Enomoto D, Matsumoto K, Yamashita T, Kobayashi A, Maeda M, Nakayama H, Obana M, Fujio Y.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 8 Pages: e0183584-e0183584
- DOI
  10.1371/journal.pone.0183584
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09576, KAKENHI-PROJECT-15K08232, KAKENHI-PROJECT-15K18987
[Journal Article] Phospholamban inhibition by a single dose administration of locked nucleic acid antisense oligonucleotide improves cardiac contractility in pressure overload-induced systolic dysfunction in mice.2017
- Author(s)
  Morihara, H., Yamamoto, T., Oiwa, H., Tonegawa, K., Tsuchiyama, D., Kawakatsu, I., Obana, M., Maeda, M., Mohri, T., Obika, S., Fujio, Y., Nakayama, H.
- Journal Title
  
  J. Cardiovasc. Pharmacol. Ther.
  
  Volume: 印刷中 Issue: 3 Pages: 273-282
- DOI
  10.1177/1074248416676392
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293054, KAKENHI-PROJECT-15K15052, KAKENHI-PROJECT-15K08232, KAKENHI-PROJECT-17K09576
[Journal Article] Adult murine cardiomyocytes exhibit regenerative activity with cell cycle reentry through STAT3 in the healing process of myocarditis.2017
- Author(s)
  Miyawaki A, Obana M, Mitsuhara Y, Orimoto A, Nakayasu Y, Yamashita T, Fukada SI, Maeda M, Nakayama H, Fujio Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 1407-1407
- DOI
  10.1038/s41598-017-01426-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09576, KAKENHI-PROJECT-15K08232, KAKENHI-PROJECT-15K18987
[Journal Article] A mouse model of Epstein-Barr virus LMP1 and LMP2A driven germinal center B-cell lymphoproliferative disease.2017
- Author(s)
  1Minamitani, T., Ma, Y., Zhou, H., Kida, H., Tsai, C.-Y., Obana, M., Okuzaki, D., Fujio, Y., Kumanogoh, A., Kikutani, H., Zhao, B., Kieff, E., Gewuz, B. E., Yasui, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 印刷中 Issue: 18 Pages: 4751-4756
- DOI
  10.1073/pnas.1701836114
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293054, KAKENHI-PROJECT-25461157, KAKENHI-PROJECT-16K09537, KAKENHI-PROJECT-16K14650
[Journal Article] 2-aminoethoxydiphenyl borate provides an anti-oxidative effect and mediates cardioprotection during ischemia reperfusion in mice.2017
- Author(s)
  Morihara H, Obana M, Tanaka S, Kawakatsu I, Tsuchiyama D, Mori S, Suizu H, Ishida A, Kimura R, Tsuchimochi I, Maeda M, Yoshimitsu T, Fujio Y, Nakayama H.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 12 Pages: e0189948-e0189948
- DOI
  10.1371/journal.pone.0189948
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09576, KAKENHI-PROJECT-15K08232, KAKENHI-PROJECT-15K14977
[Journal Article] Four cases of investigational therapy with interleukin-11 against acute myocardial infarction.2016
- Author(s)
  Nakagawa, M., Owada Y., Izumi, Y., Nonin, S., Sugioka, K., Iwata, S., Mizutani, K., Nishimura, S., It, A., Fujita, S., Daimon, T., Sawa, Y., Asakura, M., Maeda, M., Fujio, Y., Yoshiyama, M.
- Journal Title
  
  Heart and Vessels
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08232
[Journal Article] Four cases of investigational therapy with interleukin-11 against acute myocardial infarction.2016
- Author(s)
  Nakagawa, M., Owada Y., Izumi, Y., Nonin, S., Sugioka, K., Nakatani, D., Iwata, S., Mizutani, K., Nishimura, S., It, A., Fujita, S., Daimon, T., Sawa, Y., Asakura, M., Maeda, M., Fujio, Y., Yoshiyama, M.
- Journal Title
  
  Heart and Vessels
  
  Volume: 31 Issue: 9 Pages: 1574-1578
- DOI
  10.1007/s00380-015-0788-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293054, KAKENHI-PROJECT-26460344, KAKENHI-PROJECT-15K08232, KAKENHI-PROJECT-15K08649, KAKENHI-PROJECT-16K09450
[Journal Article] Moesin is activated in cardiomyocytes in experimental autoimmune myocarditis and mediates cytoskeletal reorganization with protrusion formation2016
- Author(s)
  Akimitsu Miyawaki, Yusuke Mitsuhara, Aya Orimoto, Yusuke Nakayasu, Shin-ichi Tsunoda, Masanori Obana, Makiko Maeda, Hiroyuki Nakayama, Yasuo Yoshioka, Yasuo Tsutsumi, Yasushi Fujio
- Journal Title
  
  The American Journal of Physiology-Heart and Circulatory Physiology
  
  Volume: 311 Issue: 2 Pages: 476-486
- DOI
  10.1152/ajpheart.00180.2016
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J05326, KAKENHI-PROJECT-26293054, KAKENHI-PROJECT-15K15052, KAKENHI-PROJECT-15K08232, KAKENHI-PROJECT-15K18987
[Journal Article] Myeloid cell-derived LRG attenuates adverse cardiac remodeling after myocardial infarction.2016
- Author(s)
  Kumagai, S., Nakayama, H., Fujiomoto, M., Honda, H., Serada, S., Ishibashi-Ueda, H., Kasai, A., Obana, M., Sawa, Y., Fujio, Y., Naka, T.
- Journal Title
  
  Cardiovasc. Res.
  
  Volume: 109 Issue: 2 Pages: 272-282
- DOI
  10.1093/cvr/cvv273
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293054, KAKENHI-PROJECT-15K15052
[Journal Article] Four cases of investigational therapy with interleukin-11 against acute myocardial infarction.2016
- Author(s)
  Nakagawa, M., Owada Y., Izumi, Y., Nonin, S., Sugioka, K., Iwata, S., Mizutani, K., Nishimura, S., It, A., Fujita, S., Daimon, T., Sawa, Y., Asakura, M., Maeda, M., Fujio, Y., Yoshiyama, M.
- Journal Title
  
  Heart and Vessels
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293054
[Journal Article] Interleukin-27 induces the endothelial differentiation in Sca-1+ cardiac resident stem cells.2015
- Author(s)
  Tanaka, T., Obana, M., Mohri, T., Maeda, M., Fujio, Y.
- Journal Title
  
  Cytokine
  
  Volume: 75 Issue: 2 Pages: 365-372
- DOI
  10.1016/j.cyto.2015.06.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08232, KAKENHI-PROJECT-25860061, KAKENHI-PROJECT-26293054
[Journal Article] Vascular functional and morphological alteration in smokers during varenicline therapy.2015
- Author(s)
  Kobayashi, M., Takemoto, Y., Norioka, N., Iguchi, Y., Shimada, K., Maeda, M., Morimura, M., Fujio, Y., Azuma, ., Yoshiyama, M., Hirohashi, K., Shuto, T.
- Journal Title
  
  Osaka City Med. J.
  
  Volume: 61 Pages: 19-30
- NAID
  120006493315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08232
[Journal Article] Cardiac specific ablation of STAT3 gene in subacute phase of myocardial infarction exacerbated cardiac remodeling.2015
- Author(s)
  Enomoto, D., Obana, M., Miyawaki, A., Maeda, M., Nakayama, H., Fujio, Y.
- Journal Title
  
  Am. J. Physiol. Heart Circ. Physiol.
  
  Volume: 3０９ Issue: 3 Pages: H471-H480
- DOI
  10.1152/ajpheart.00730.2014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08232, KAKENHI-PROJECT-15K15052, KAKENHI-PROJECT-26293054
[Journal Article] The Inhibition of N-Glycosylation of Glycoprotein 130 Molecule Abolishes STAT3 Activation by IL-6 Family Cytokines in Cultured Cardiac Myocytes.2014
- Author(s)
  Matsuo R, Morihara H, Mohri T, Murasawa S, Takewaki K, Nakayama H, Maeda M, Fujio Y.
- Journal Title
  
  PLoS One
  
  Volume: 23 Issue: 10 Pages: e111097-e111097
- DOI
  10.1371/journal.pone.0111097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670193, KAKENHI-PROJECT-25670387, KAKENHI-PROJECT-25860061, KAKENHI-PROJECT-26293054
[Journal Article] Minimal dose for effective clinical outcome and predictive factors for responsiveness to carvedilol: Japanese chronic heart failure (J-CHF) study.2013
- Author(s)
  Okamoto, H., Hori, M., Matsuzaki, M., Tsutsui, H., Yamazaki, T., Nagai, R., Yoshikawa, T., Fujio, Y., Nonen, S. Azuma, J., Izumi, T., Ohashi, Y., Kitabatake, A. on behalf of J-CHF investigators.
- Journal Title
  
  Int. J. Cardiol.
  
  Volume: 164 Issue: 2 Pages: 238-244
- DOI
  10.1016/j.ijcard.2012.11.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390057, KAKENHI-PROJECT-23390143, KAKENHI-PROJECT-23591062, KAKENHI-PROJECT-25670193
[Journal Article] Polymorphisms of CYP2D6 gene and gefitinib-induced hepatotoxicty2013
- Author(s)
  Takimoto, T., Kijima, T., Otani, Y., Nonen, S., Namba, Y., Mori, M., Yokota, S., Minami, S., Komuta, K., Uchida, J., Imamura, F., Furukawa, M., Tsuruta, N., Fujio, Y., Azuma, J., Tachibana, I., Kumanogoh, A
- Journal Title
  
  Clin. Lung Cancer
  
  Volume: 14 Pages: 502-507
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Genetic polymorphisms of CYP17A1 in steroidogenesis pathway are associated with risk of progression to castration-resistant prostate cancer in Japanese men receiving androgen deprivation therapy2013
- Author(s)
  Yamada, T. Nakayama, M., Shimizu, T., Nonen, S., Nakai, Y., Nishimura, K., Fujio, Y., Okuyama, A., Azuma, J., Nonomura, N
- Journal Title
  
  Int. J. Clin. Oncol
  
  Volume: 18 Pages: 711-717
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Requirement of SLD5 for early embryogenesis2013
- Author(s)
  Mohri, T., Ueno, M., Nagahama, Y., Gong, Z.-Y., Asano, M., Oshima, H., Oshima, M., Fujio, Y., Takakura, N
- Journal Title
  
  PLoS One
  
  Volume: 8
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Ca2+依存性の心肥大・心筋細胞死誘導シグナル2013
- Author(s)
  中山博之、山口修、藤尾慈
- Journal Title
  
  Clinical Calcium
  
  Volume: 23 Pages: 505-515
- Data Source
  KAKENHI-PROJECT-23390212
[Journal Article] NAT2 genotype guided regimen reduces isoniazid-induced liver injury and early treatment failure in the 6-month four-drug standard treatment of tuberculosis: A randomized controlled trial for pharmacogenetics-based therapy.2013
- Author(s)
  Azuma, J. Ohno, M., Kubota, R., Yokota, S., Nagai, T., Tsuyuguchi, K., Okuda, Y., Takashima, T., Kamimura, S., Fujio, Y., Kawase, I. and Pharmacogenetics-based tuberculosis research group.
- Journal Title
  
  Eur. J. Clin. Pharmacol.
  
  Volume: 69 Issue: 5 Pages: 1091-1101
- DOI
  10.1007/s00228-012-1429-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390057, KAKENHI-PROJECT-23390143, KAKENHI-PROJECT-25670193
[Journal Article] Minimal dose for effective clinical outcome and predictive factors for responsiveness to carvedilol : Japanese chronic heart failure (J-CHF) study2013
- Author(s)
  Okamoto, H., Hori, M., Matsuzaki, M., Tsutsui, H., Yamazaki, T., Nagai, R., Yoshikawa, T., Fujio, Y., Nonen, S. Azuma, J., Izumi, T., Ohashi, Y., Kitabatake, A. on behalf of J-CHF investigators
- Journal Title
  
  Int. J. Cardiol
  
  Volume: 164 Pages: 238-244
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Cathelicidin antimicrobial peptide inhibits fibroblast migration via P2X7 receptor signaling2013
- Author(s)
  Kumagai, S., Matsui, K., Kawaguchi, H., Yamashita, T., Mohri, T., Fujio, Y., Nakayama, H
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 437 Pages: 609-614
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Calcium dependent signaling in cardiac hypertrophy and cell death2013
- Author(s)
  Nakayama H, Fujio Y, Yamaguchi O
- Journal Title
  
  Clin Calcium
  
  Volume: 23(4) Pages: 505-15
- Data Source
  KAKENHI-PROJECT-23390212
[Journal Article] Cathelicidin antimicrobial peptide inhibits fibroblast migration via P2X7 receptor signaling.2013
- Author(s)
  Kumagai, S., Matsui, K., Kawaguchi, H., Yamashita, T., Mohri, T., Fujio, Y., Nakayama, H.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 437 Issue: 4 Pages: 609-614
- DOI
  10.1016/j.bbrc.2013.07.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390057, KAKENHI-PROJECT-23390212, KAKENHI-PROJECT-25670193, KAKENHI-PROJECT-25860061
[Journal Article] Requirement of SLD5 for Early Embryogenesis.2013
- Author(s)
  Mohri T
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 11 Pages: e78961-e78961
- DOI
  10.1371/journal.pone.0078961
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112005, KAKENHI-PROJECT-23390057, KAKENHI-PROJECT-24300330, KAKENHI-PROJECT-25670193, KAKENHI-PROJECT-25860061
[Journal Article] NAT2 genotype guided regimen reduces isoniazid-induced liver injury and early treatment failure in the 6-month four-drug standard treatment of tuberculosis : A randomized controlled trial for pharmacogenetics-based therapy2013
- Author(s)
  Azuma, J. Ohno, M., Kubota, R., Yokota, S., Nagai, T., Tsuyuguchi, K., Okuda, Y., Takashima, T., Kamimura, S., Fujio, Y., Kawase, I. and Pharmacogenetics-based tuberculosis research group
- Journal Title
  
  Eur. J. Clin. Pharmacol
  
  Volume: 69 Pages: 1091-1101
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Polymorphisms of CYP2D6 gene and gefitinib-induced hepatotoxicty.2013
- Author(s)
  Takimoto, T., Kijima, T., Otani, Y., Nonen, S., Namba, Y., Mori, M., Yokota, S., Minami, S., Komuta, K., Uchida, J., Imamura, F., Furukawa, M., Tsuruta, N., Fujio, Y., Azuma, J., Tachibana, I., Kumanogoh, A.
- Journal Title
  
  Clin. Lung Cancer.
  
  Volume: 14 Issue: 5 Pages: 502-507
- DOI
  10.1016/j.cllc.2013.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390057, KAKENHI-PROJECT-23390143, KAKENHI-PROJECT-25670193
[Journal Article] Endothelial Gab1 deletion accelerates angiotensin II-dependent vascular inflammation and atherosclerosis in apolipoprotein E knockout mice2012
- Author(s)
  Higuchi, K., Nakaoka, Y., Shioyama, W., Arita, Y., Hashimoto, T., Yasui, T., Ikeoka, K., Kuroda, T., Minami, T., Nishida, K., Fujio, Y., Yamauchi-Takihara, K., Shirai, M., Mochizuki, N., Komuro, I
- Journal Title
  
  Circ. J
  
  Volume: 76 Pages: 2031-2040
- NAID
  10030505176
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Genetic polymorphisms of CYP17A1 in steroidogenesis pathway are associated with risk of progression to castration-resistant prostate cancer in Japanese men receiving androgen deprivation therapy2012
- Author(s)
  Takeshi Yamada, Masashi Nakayama, Tomohito Shimizu, Shinpei Nonen, et al.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: (in press) Issue: 4 Pages: 711-718
- DOI
  10.1007/s10147-012-0430-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790515, KAKENHI-PROJECT-23390057, KAKENHI-PROJECT-23390143, KAKENHI-PROJECT-25670193
[Journal Article] Therapeutic administration of IL-11 exhibits the postconditioning effects against ischemia-reperfusion injury via STAT3 in the heart2012
- Author(s)
  Obana, M. Miyamoto, K., Murasawa, S., Iwakura, T., Hayama, A., Yamashita, T., Shiragaki, M., Kumagai, S., Miyawaki, A., Takewaki, K., Matsumiya, G., Maeda, M., Yoshiyama, M., Nakayama, H., Fujio, Y
- Journal Title
  
  Am. J. Physiol. Heart Circ. Physiol
  
  Volume: 303
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Therapeutic administration of IL-11 exhibits the postconditioning effects against ischemia-reperfusion injury via STAT3 in the heart2012
- Author(s)
  Obana M, Miyamoto K, Murasawa S, Iwakura T, Hayama A, Yamashita T,Shiragaki M, Kumagai S, Miyawaki A, Takewaki K, Matsumiya G, Maeda M, Yoshiyama M, Nakayama H, Fujio Y.
- Journal Title
  
  Am J Physiol Heart Circ. Physiol
  
  Volume: 303(5) Issue: 5 Pages: 569-77
- DOI
  10.1152/ajpheart.00060.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590160, KAKENHI-PROJECT-24591066
[Journal Article] JAK/STAT signaling in cardiomyogenesis of cardiac stem cells2012
- Author(s)
  Mohri, T., Iwakura, T., Nakayama, H. Fujio, Y
- Journal Title
  
  JAK/STAT
  
  Volume: 1 Pages: 125-130
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Gp130 cytokine signal as a therapeutic target against cardiovascular diseases2011
- Author(s)
  Fujio, Y., et al
- Journal Title
  
  J.Pharmacol.Sci.
  
  Volume: 117 Pages: 213-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Association between osteopontin promoter variants and diastolic dysfunction in hypertensive heart in the Japanese population2011
- Author(s)
  Nakayama, H., Nagai, H., Matsumoto, K., Oguro, R., Sugimoto, K., Kamide, K., Ohishi, M., Katsuya, T., Okamoto, H., Maeda, M., Komamura, K., Azuma, J., Rakugi, H., Fujio, Y
- Journal Title
  
  Hypertension Res
  
  Volume: 34 Pages: 1141-1146
- NAID
  10030276721
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] IL-6-mediated Th17 differentiation through RORγt is essential for the initiation of experimental autoimmune myocarditis2011
- Author(s)
  Yamashita, T., Iwakura, T., Matsui, K., Kawaguchi, H., Obana, M., Hayama, A., Maeda, M, Izumi, Y., Komuro, I., Ohsugi, Y., Fujimoto, M., Naka, T., Kishimoto, T., Nakayama, H., Fujio, Y
- Journal Title
  
  Cardiovasc. Res
  
  Volume: 91 Pages: 640-648
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] IL-6-mediated Th17 differentiation through RORγt is essential for the initiation of experimental autoimmune myocarditis.2011
- Author(s)
  Yamashita T, Iwakura T, Matsui K, Kawaguchi H, Obana M, Hayama A,Maeda M, Izumi Y, Komuro I, Ohsugi Y, Fujimoto M, Naka T, Kishimoto T, Nakayama H, Fujio Y.
- Journal Title
  
  Cardiovasc Res.
  
  Volume: 91(4) Pages: 640-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590160
[Journal Article] Cigarette smoke extract induces CYP2B6 through constitutive androstane receptor in hepatocytes2011
- Author(s)
  Washio, I., Maeda, M.(2), Fujio, Y.(7), Azuma, J.(8)
- Journal Title
  
  Drug Metab. Dispos
  
  Volume: 39 Pages: 1-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590834
[Journal Article] Docking protein Gab1 is an essential component of postnatal angiogenesis after ischemia via HGF/c-Met signaling2011
- Author(s)
  Shioyama, W., Nakaoka, Y., Higuchi, K., Minami, T., Taniyama, Y., Nishida, K., Kidoya, H., Naito, H., Arita, Y., Hashimoto, T., Sanada, F., Fujio, Y., Shirai, M., Takakura, N., Morishita, R., Yamauchi-Takihara, K., Kodama, T., Hirano, T., Mochizuki, N., Komuro, I
- Journal Title
  
  Circ. Res
  
  Volume: 108 Pages: 664-675
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Cigarette smoke extract induces CYP2B6 through constitutive androstane receptor in hepatocytes2011
- Author(s)
  Washio, I. Maeda, M., Sugiura, C., Shiga, R., Yoshida, M., Nonen, S., Fujio, Y., Azuma, J
- Journal Title
  
  Drug Metab. Dispos
  
  Volume: 39 Pages: 1-3
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] STAT3/Pim-1 signaling pathway plays a crucial role in endothelial differentiation of cardiac resident Sca-1+ cells both in vitro and in vivo2011
- Author(s)
  Iwakura, T., Mohri, T., Hamatani, T., Obana, M., Yamashita, T., Maeda, M., Katakami, N., Kaneto, H., Komuro, I., Azuma, J., Nakayama, H., Fujio, Y
- Journal Title
  
  J. Mol. Cell. Cardiol
  
  Volume: 51 Pages: 207-214
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Cigarette smoke extract induces CYP2B6 through constitutive androstane receptor in hepatocytes2011
- Author(s)
  Ikumi Washio, Makiko Maeda, Chika Sugiura, Ryota Shiga, Mitsuhiro Yoshida, Shinpei Nonen, Yasushi Fujio, Junichi Azuma
- Journal Title
  
  Drug Metabolism and Disposition
  
  Volume: 39 Pages: 1-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590160
[Journal Article] Glycoprotein130 cytokine signal as a therapeutic target against cardiovascular diseases2011
- Author(s)
  Fujio, Y., Maeda, M., Mohri, M., Obana, M., Iwakura, T., Hayama, A., Yamashita, T., Nakayama, H., Azuma, J
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 117 Pages: 213-222
- NAID
  10030453480
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] STAT3/Pim-1 signaling pathway plays a crucial role in endothelial differentiation of cardiac resident stem cells both in vitro and in vivo.2011
- Author(s)
  Iwakura T., Mohri T., Hamatani T., Obana M., Yamashita T., Maeda M., Katakami N., Kaneto H., Komuro I., Azuma J., Nakayama H., Fujio Y.
- Journal Title
  
  J.Mol.Cell.Cardiol. In press
- Data Source
  KAKENHI-PROJECT-20390069
[Journal Article] Gp130 cytokine signal as a therapeutic target against cardiovascular diseases2011
- Author(s)
  Fujio, Y.
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 117 Pages: 213-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591056
[Journal Article] Safe and successful treatment with erlotinib after gefitinib-induced hepatotoxicity : difference in metabolism as a possible mechanism2011
- Author(s)
  Kijima, T., Shimizu, T., Nonen, S., Furukawa, M., Otani, Y., Minami, T., Takahashi, R., Hirata, H., Nagatomo, I., Takeda, Y., Kida, H., Goya, S., Fujio, Y., Azuma, J., Tachibana, I., Kawase, I
- Journal Title
  
  J. Clin. Oncol
  
  Volume: 29
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Gp130 cytokine signal as a therapeutictarget against cardiovascular diseases.2011
- Author(s)
  Fujio Y, Maeda M, Mohri T, Obana M, Iwakura T, Hayama A, Yamashita T, Nakayama H, Azuma J.
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 117(4) Pages: 213-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590160
[Journal Article] Gp130 cytokine signal as a therapeutic target against cardiovascular diseases2011
- Author(s)
  Fujio Y, et al
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 117(4) Pages: 213-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590160
[Journal Article] Therapeutic activation of STAT3 by interleukin-11 ameliorates cardiac fibrosis after myocardial infarction.2010
- Author(s)
  Obana M., Maeda M., Takeda K., Hayama A., Mohri T., Yamashita T., Nakaoka Y., Komuro I., Takeda K., Matsumiya G., Azuma J., Fujio Y.
- Journal Title
  
  Circulation. 121
  
  Pages: 684-691
- Data Source
  KAKENHI-PROJECT-20390069
[Journal Article] IL-11の心血管系における作用2010
- Author(s)
  尾花理徳、前田真貴子、藤尾慈
- Journal Title
  
  循環器科 67
  
  Pages: 156-162
- Data Source
  KAKENHI-PROJECT-20390069
[Journal Article] SHP2 negatively regulates skeletal alpha-actin gene expression downstream of gp130 signaling in cardiomyocytes.2010
- Author(s)
  Nakaoka Y., Shioyama W., Kunimoto S., Fujio Y., Higuchi K., Nishida K., Arita, Y., Kuroda T., Hirota H., Yamauchi-Takihara K., Hirano T., Komuro I., Mochizuki N.
- Journal Title
  
  J.Mol.Cell.Cardiol. 49
  
  Pages: 157-164
- Data Source
  KAKENHI-PROJECT-20390069
[Journal Article] Therapeutic activation of STAT3 by interleukin-11 ameliorates cardiac fibrosis after myocardial infarction2010
- Author(s)
  Obana, M., Maeda, M., Azuma, J., Fujio, Y.
- Journal Title
  
  Circulation
  
  Volume: 121 Pages: 684-691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590834
[Journal Article] 循環器内科;IL-11 の心血管系における作用2010
- Author(s)
  尾花理徳、前田真貴子、藤尾慈
- Journal Title
  
  循環器内科(科学評論社)
  
  Volume: 67(2) Pages: 156-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590160
[Journal Article] RGS2 determines the preventive effects of ARB against vascular remodeling : Toward personalized medicine of ARB in anti-hypertensive therapy2010
- Author(s)
  Fujio, Y.
- Journal Title
  
  Hypertension Res
  
  Volume: 33 Pages: 1221-1222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590834
[Journal Article] Cardiac skeletal muscle abnormality in taurine transporter-knockout mice2010
- Author(s)
  Ito, T., Fujio, Y.(6), Schaffer, S. W., Azuma, J.(8)
- Journal Title
  
  J. Biomed. Sci
  
  Volume: 17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590834
[Journal Article] RGS2 determines the preventive effects of ARB against vascular remodeling : Toward personalized medicine of ARB in anti-hypertensive therapy.2010
- Author(s)
  Fujio, Y.
- Journal Title
  
  Hypertension.Res.
  
  Volume: 33 Pages: 1221-1222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390069
[Journal Article] Signals through glycoprotein 130 regulate the endothelial differentiation of cardiac stem cells. Arterioscler.2009
- Author(s)
  Mohri T., Fujio Y., Iwakura T., Matsuda K., Maeda M., Azuma J.
- Journal Title
  
  Thromb.Vasc.Biol. 29
  
  Pages: 754-760
- Data Source
  KAKENHI-PROJECT-20390069
[Journal Article] Beneficial effect of taurine treatment against doxorubicin-induced cardiotoxicity in mice2009
- Author(s)
  Ito, T., Fujio, Y., Azuma, J.
- Journal Title
  
  Adv. Exp. Med. Biol
  
  Volume: 643 Pages: 65-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590834
[Journal Article] Signals through glycoprotein 130 regulate the endothelial differentiation of cardiac stem cells2009
- Author(s)
  Mohri, T., Fujio, Y., Maeda, M., Azuma, J.
- Journal Title
  
  Arterioscler. Thromb. Vasc. Biol
  
  Volume: 29 Pages: 754-760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590834
[Journal Article] Influence of clinical and genetic factors on warfarin dose requirements among Japanese patients2009
- Author(s)
  Ohno, M., Yamamoto, A., Takemoto, Y.(6), Fujio, Y.(12), Azuma, J.(13)
- Journal Title
  
  Eur. J. Clin. Pharmcol
  
  Volume: 65 Pages: 1097-1103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590834
[Journal Article] Involvement of transcriptional factor TonEBP in the regulation of the taurine transporter in the cardiomyocyte2009
- Author(s)
  Ito, T., Fujio, Y., Azuma, J.
- Journal Title
  
  Adv. Exp. Med. Biol
  
  Volume: 643 Pages: 523-532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590834
[Journal Article] Atrogin-1 ubiquitin ligase is upregulated by doxorubicin via p38 MAP kinase in cardiac myocytes.2008
- Author(s)
  Yamamoto, Y., Hoshino, Y., Ito, T., Nariai, T., Mohri, T., Obana M., Hayata, N., Uozumi, Y., Maeda M., Fujio Y., Azuma, J.
- Journal Title
  
  Cardiovasc.Res. 79
  
  Pages: 89-96
- Data Source
  KAKENHI-PROJECT-20390069
[Journal Article] MTHFR gene polymorphism is susceptible to diabetic retinopathy but not to diabetic nephropathy in Japanese type 2 diabetic patients2008
- Author(s)
  Maeda, M., Fujio, Y., Azuma, J.
- Journal Title
  
  J. Diabetes Complications
  
  Volume: 22 Pages: 119-125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590834
[Journal Article] Atrogin-1 ubiquitin ligase is upregulated by doxorubicin via p38 MAP kinase in cardiac myocytes2008
- Author(s)
  Yamamoto, Y., Maeda, M., Fujio, Y., Azuma, J.
- Journal Title
  
  Cardiovasc. Res
  
  Volume: 79 Pages: 89-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590834
[Journal Article] Polymorphisms of norepinephrine transporter and adrenergic receptor alpha1D are associated with the response to beta-blockers in dilated cardiomyopathy2008
- Author(s)
  Nonen, S., Fujio, Y., Takemoto, Y., Yoshiyama, M., Azuma, J.
- Journal Title
  
  Pharmacogenomics J
  
  Volume: 8 Pages: 78-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590834
[Journal Article] Connective tissue growth factor induces cardiac hypertrophy through Akt signaling2008
- Author(s)
  Hayata, N., Fujio, Y., Maeda, M., Azuma, J.
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 370 Pages: 274-278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590834
[Journal Article] Taurine depletion caused by knocking out the taurine transporter gene leads to cardiomyopathy with cardiac atrophy2008
- Author(s)
  Ito, T., Yoshiyama, M.(8), Fujio, Y.(12), Azuma, J.(13)
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 5 Pages: 927-937
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590834
[Journal Article] Degradation of NFAT5, a transcriptional regulator of osmotic stress-related genes, is a critical event for doxorubicin-induced cytotoxicity in cardiac myocytes2007
- Author(s)
  Ito, T., Fujio, Y., Takahashi, K., et. al.
- Journal Title
  
  J. Biol. Chem 282
  
  Pages: 1152-1160
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390065
[Journal Article] Leukemia inhibitory factor induces endothelial differentiation in cardiac stem cells2006
- Author(s)
  Mohri, T., Fujio, Y, Maeda, M., et. al.
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 6442-6447
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390065
[Journal Article] N-cadherin signals through Racl determined the localization of connexin 43 in cardiac myocytes2006
- Author(s)
  Matsuda, T., Fujio, Y, Nariai, T., et. al.
- Journal Title
  
  J. Mol. Cell. Cardiol 40
  
  Pages: 495-502
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390065
[Journal Article] STAT3 mediates cardioprotection against ischemia/reperfusion injury through metallothionein induction in the heart2005
- Author(s)
  Oshima, Y, Fujio, Y., Nakanishi, T., et. al.
- Journal Title
  
  Cardiovasc. Res 65
  
  Pages: 428435-428435
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390065
[Journal Article] Signals through gp130 upregulate Wnt5a and contribute to cell adhesion in cardiac myocytes2004
- Author(s)
  Fujio, Y., Matsuda, T., Oshima, Y., et. al.
- Journal Title
  
  FEBS letters 573
  
  Pages: 202-206
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390065
[Journal Article] Signals through gp130 upregulate Wnt5a and contribute to cell adhesion in cardiac myocytes2004
- Author(s)
  Fujio, Y., et. al.
- Journal Title
  
  FEBS letters 573
  
  Pages: 202-206
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390065
[Journal Article] Signals through gp130 upregulate Wnt5a and contribute to cell adhesion in cardiac myocytes2004
- Author(s)
  Fujio, Y., et al.
- Journal Title
  
  FEBS letters 573
  
  Pages: 202-206
- Data Source
  KAKENHI-PROJECT-16390065
[Journal Article] Requirement of SLD5 for early embryo-genesis
- Author(s)
  Mohri T, Ueno M, Nagahama Y, Gong ZY, Asano M, Oshima H, Oshima M, Fujio Y, Takakura N
- Journal Title
  
  PLoS One
  
  Volume: 8(11)
- Data Source
  KAKENHI-PROJECT-23390212
[Journal Article] Cathelicidin antimicrobial peptide inhibits fibroblast migration via P2X7 receptor signaling
- Author(s)
  Kumagai S, Matsui K, Kawaguchi H, Yamashita T, Mohri T, Fujio Y, Nakayama H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 437(4) Pages: 609-14
- Data Source
  KAKENHI-PROJECT-23390212
[Patent] インターロイキン11の心疾患治療薬としての利用2013
- Inventor(s)
  東純一, 藤尾慈, 木村竜介, 前田真貴子, 有田惇之, 尾花理徳, 伊藤崇志, 福田剛史
- Industrial Property Rights Holder
  国立大学法人大阪大学
- Acquisition Date
  2013-02-08
- Data Source
  KAKENHI-PROJECT-23390057
[Patent] Use of interleukin-11 as therapeutic agent for heart disease2013
- Inventor(s)
  東純一, 藤尾慈, 木村竜介, 前田真貴子, 有田惇之, 尾花理徳, 伊藤崇志, 福田剛史
- Industrial Property Rights Holder
  国立大学法人大阪大学
- Acquisition Date
  2013-01-29
- Overseas
- Data Source
  KAKENHI-PROJECT-23390057
[Patent] インターロイキン11の心疾患治療薬としての利用2007
- Inventor(s)
  東純一、藤尾慈, 他6名
- Industrial Property Rights Holder
  大阪大学
- Filing Date
  2007-10-24
- Overseas
- Data Source
  KAKENHI-PROJECT-16390065
[Patent] インターロイキン11の心疾患治療薬としての利用2007
- Inventor(s)
  東純一、藤尾慈、木村竜介、前田真貴子、有田惇之、尾花理徳、伊藤崇志、福田剛史
- Industrial Property Rights Holder
  新産業創造研究機構、大阪大学
- Filing Date
  2007-10-24
- Description
  「研究成果報告書概要(和文)」より
- Overseas
- Data Source
  KAKENHI-PROJECT-16390065
[Patent] UGT1A1遺伝子多型の検出法2005
- Inventor(s)
  東純一, 藤尾慈, 福田剛史, 大野雅子, 田邊智子
- Industrial Property Rights Holder
  国立大学法人大阪大学, 財団法人新産業創造研究機構
- Industrial Property Number
  2005-325757
- Filing Date
  2005-11-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390042
[Presentation] 大規模医療情報データベースを用いた日本における降圧薬の有害事象発現状況の調査2023
- Author(s)
  細美友里瑛、前田真貴子、廣部祥子、前田真一郎、神出計、藤尾慈
- Organizer
  第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07218
[Presentation] Warfarin投与量予測モデルにおけるPT-INR欠測値補完方法の探索2023
- Author(s)
  弓場遼真、齊藤茉莉佳、前田真一郎、廣部祥子、藤尾慈、前田真貴子
- Organizer
  第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06740
[Presentation] 慢性心不全患者における高齢がβ- blockerの投与量、有効性及び安全性に及ぼす影響に関する調査2023
- Author(s)
  武田汐莉、六車萌恵、前田真一郎、廣部祥子、藤尾慈、前田真貴子
- Organizer
  第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07218
[Presentation] Cardioprotective roles of novel cell death inhibitor, defender against cell death 1 （Dad1）2021
- Author(s)
  森　翔太、田中翔大、前田真貴子、尾花理徳、藤尾　慈
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K21575
[Presentation] TGFβ3は梗塞後心筋リモデリングを増悪させる2021
- Author(s)
  冨松聖史、横田洸成、小南春祐、田中翔大、前田真貴子、岡田欣晃、尾花理徳、藤尾慈
- Organizer
  第95回日本薬理学会
- Data Source
  KAKENHI-PROJECT-20K21575
[Presentation] Increased Old Astrocyte Specifically Induced Scbstance (OASIS) in podocytes leads to the progression of nephrotic syndrome2021
- Author(s)
  Miyake Y, Obana M, Yamamoto A, Noda S, Tanaka K, Tanaka S, Maeda M, Asanuma K, Fujio Y.
- Organizer
  American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21575
[Presentation] 細胞周期感受性タンパクFUCCIを用いた新規心筋増殖関連因子の網羅的探索2021
- Author(s)
  和田祐理子、亀谷祐介、鈴木翔大、梅田綾香、西中康介、田中翔大、前田真貴子、岡田欣晃、尾花理徳、藤尾慈
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K21575
[Presentation] Activation of YAP is essential for the myocardial recovery from myocarditis2021
- Author(s)
  福山尚希、亀谷祐介、和田祐理子、鈴木翔大、梅田綾香、前田真貴子、田中翔大、尾花理徳、藤尾　慈
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K21575
[Presentation] 培養心筋細胞における内因性YAP活性は、GSK3阻害剤による増殖誘導効果を増強する2021
- Author(s)
  亀谷祐介、田中翔大、鈴木翔大、梅田綾香、前田真貴子、岡田欣晃、尾花理徳、藤尾慈
- Organizer
  第31回日本循環薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K21575
[Presentation] Cardioprotective roles of novel cell death inhibitor, defender against cell death 1 (Dad1)2021
- Author(s)
  森　翔太、田中翔大、前田真貴子、尾花理徳、藤尾　慈
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] CXCL10 is an anti-angiogenic factor downstream of p53 in cardiomyocytes2021
- Author(s)
  五十嵐竜太、冨松聖史、前田真貴子、田中翔大、尾花理徳、藤尾　慈
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] Activation of YAP is essential for the myocardial recovery from myocarditis2021
- Author(s)
  福山尚希、亀谷祐介、和田祐理子、鈴木翔大、梅田綾香、前田真貴子、田中翔大、尾花理徳、藤尾　慈
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] CXCL10 is an anti-angiogenic factor downstream of p53 in cardiomyocytes2021
- Author(s)
  五十嵐竜太、冨松聖史、前田真貴子、田中翔大、尾花理徳、藤尾　慈
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K21575
[Presentation] Dad1は細胞接着の障害によって誘導される心筋細胞死を抑制する2020
- Author(s)
  森翔太, 木村瑠美, 渕上翔太, 松本浩太朗, 前田真貴子, 尾花理徳, 藤尾慈
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] 心線維芽細胞β2アドレナリン受容体シグナルはパラクラインを介して心臓の肥大を惹起する2020
- Author(s)
  今枝厚貴、田中翔大、松本浩太朗、前田真貴子、尾花理徳、藤尾慈
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] 細胞死が惹起する心筋炎症と組織修復：新たな心不全治療を目指して2020
- Author(s)
  藤尾　慈、宮脇昭光、尾花理徳、松本浩太朗、前田真貴子
- Organizer
  日本薬学会第140年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19545
[Presentation] 心線維芽細胞β2アドレナリン受容体シグナルはパラクラインを介して心臓の肥大を惹起する2020
- Author(s)
  今枝厚貴、田中翔大、松本浩太朗、前田真貴子、尾花理徳、藤尾慈
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K19545
[Presentation] 哺乳類心筋細胞の細胞周期活性誘導化合物のスクリーニング系の構築2020
- Author(s)
  松井理紗、福山尚希、亀谷祐介、和田祐理子、松本浩太朗、前田真貴子、尾花理徳、藤尾慈
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K19545
[Presentation] アドレナリンβ2受容体刺激はｃＡＭＰ/PKA/CREB経路を介したArid5a発現誘導によりIL-6の産生を亢進させる2020
- Author(s)
  田中翔大、今枝厚貴、松本浩太朗、前田真貴子、尾花理徳、藤尾慈
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K19545
[Presentation] アドレナリンβ2受容体刺激はｃＡＭＰ/PKA/CREB経路を介したArid5a発現誘導によりIL-6の産生を亢進させる2020
- Author(s)
  田中翔大、今枝厚貴、松本浩太朗、前田真貴子、尾花理徳、藤尾慈
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] 転写因子OASISの阻害は腎線維化を抑制する2020
- Author(s)
  山本彩葉、尾花理徳、中江崇文、三宅芳明、光岡小百合、前田真貴子、今泉和則、松本浩太朗、藤尾慈
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] Adult murine cardiomyocytes exhibit reparative/regenerative activities in the healing process of myocarditis.2020
- Author(s)
  Fujio, Y., Miyawaki, A., Matsumoto, K., Tanaka, S., Maeda, M., Obana, M.
- Organizer
  4th Annual 2020 International Hawaii Cardiovascular Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] Dad1は細胞接着の障害によって誘導される心筋細胞死を抑制する2020
- Author(s)
  森翔太、木村瑠美、渕上翔太、松本浩太朗、前田真貴子、尾花理徳、藤尾慈
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K19545
[Presentation] Adult murine cardiomyocytes exhibit reparative/regenerative activities in the healing process of myocarditis.2020
- Author(s)
  Fujio, Y., Miyawaki, A., Matsumoto, K., Tanaka, S., Maeda, M., Obana, M.
- Organizer
  4th Annual 2020 International Hawaii Cardiovascular Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19545
[Presentation] 炎症抑制脂質分子Maresin １は新生児ラット培養心筋細胞において生理的肥大を惹起する2020
- Author(s)
  小林亜里沙、トリワヒュニ、五十嵐竜太、冨松聖史、松本浩太朗、前田真貴子、尾花理徳、藤尾慈
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] 転写因子OASISの阻害は腎線維化を抑制する2020
- Author(s)
  山本彩葉、尾花理徳、中江崇文、三宅芳明、光岡小百合、前田真貴子、今泉和則、松本浩太朗、藤尾慈
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K19545
[Presentation] 哺乳類心筋細胞の細胞周期活性誘導化合物のスクリーニング系の構築2020
- Author(s)
  松井理紗、福山尚希、亀谷祐介、和田祐理子、松本浩太朗、前田真貴子、尾花理徳、藤尾慈
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] 細胞死が惹起する心筋炎症と組織修復：新たな心不全治療を目指して2020
- Author(s)
  藤尾　慈、宮脇昭光、尾花理徳、松本浩太朗、前田真貴子
- Organizer
  日本薬学会第140年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] Molecular mechanisms of myocardial reverse remodeling after myocarditis2020
- Author(s)
  Yasushi Fujio
- Organizer
  Basic Cardiovascular Science 2020 Scientific Sessions
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21575
[Presentation] Molecular mechanisms of myocardial reverse remodeling after myocarditis2020
- Author(s)
  Yasushi Fujio
- Organizer
  Basic Cardiovascular Science 2020 Scientific Sessions
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] ワルファリン維持投与量決定におけるCYP4F2及びNQO1遺伝子多型の意義2020
- Author(s)
  齊藤茉莉佳、南畝晋平、藤尾慈、前田真貴子
- Organizer
  第41回臨床薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07218
[Presentation] Runx2発現ミエロイド細胞は梗塞後心筋リモデリングを抑制する新規心保護サブセットである2019
- Author(s)
  松本浩太朗、芦塚萌、熊谷渉平、奥崎大介、尾花理徳、前田真貴子、中山博之、藤尾　慈
- Organizer
  日本薬理学会92回年会
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] 成体マウスにおける単核心筋細胞の特性解析2019
- Author(s)
  中安佑介、松井理紗、福山尚希、亀谷祐介、和田祐理子、尾花理徳、前田真貴子、中山博之、藤尾慈
- Organizer
  日本薬理学会92回年会
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] ポドサイトにおけるOASISの発現抑制は糖尿病による腎機能の悪化を抑制する2019
- Author(s)
  4.三宅芳明、尾花威徳、山本彩葉、野田竣介、金本聡自、前田真貴子、淺沼克彦、今泉和則、中山博之、藤尾慈
- Organizer
  日本薬理学会92回年会
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] 成体マウスにおける単核心筋細胞の特性解析2019
- Author(s)
  中安佑介、松井理紗、福山尚希、亀谷祐介、和田祐理子、尾花理徳、前田真貴子、中山博之、藤尾慈
- Organizer
  日本薬理学会92回年会
- Data Source
  KAKENHI-PROJECT-18K19545
[Presentation] CGRRF1の過剰発現は培養心筋細胞の肥大を誘導する2019
- Author(s)
  木下真希、尾花理徳、前田真貴子、中山博之、藤尾慈
- Organizer
  日本薬理学会92回年会
- Data Source
  KAKENHI-PROJECT-18K19545
[Presentation] CGRRF1の過剰発現は培養心筋細胞の肥大を誘導する2019
- Author(s)
  木下真希、尾花理徳、前田真貴子、中山博之、藤尾慈
- Organizer
  日本薬理学会92回年会
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] Pharmacogenomics-Based Prediction of Warfarin Maintenance Dose Overrides Racial Differences2018
- Author(s)
  Sasano, M.,Maeda, M.,Ohno, M.,Fukuda, Y.,Yokoyama, J.,Maeda, S.,Miyagawa, S.,Sawa, Y.,Fujio,Y.
- Organizer
  American Heart Association Scientific Sessions 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] Blockade of NKG2D / NKG2D Ligand Interaction Attenuated Post-Infarct Myocardial Injury.2018
- Author(s)
  Matsumoto, K., Obana, M., Kobayashi, A.,Kihara, M.,Shioi, G., Miyagawa, S., Maeda, M.,Sakata,Y., Nakayama, H., Sawa, Y.,Fujio, Y.
- Organizer
  American Heart Association Scientific Sessions 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19545
[Presentation] Blockade of NKG2D / NKG2D Ligand Interaction Attenuated Post-Infarct Myocardial Injury.2018
- Author(s)
  Matsumoto, K., Obana, M., Kobayashi, A.,Kihara, M.,Shioi, G., Miyagawa, S., Maeda, M.,Sakata,Y., Nakayama, H., Sawa, Y.,Fujio, Y.
- Organizer
  American Heart Association Scientific Sessions 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] Blockade of NKG2D / NKG2D ligands interaction as a novel therapeutic strategy against heart failure2018
- Author(s)
  Matsumoto. K., Obana. M., Maeda. M., Nakayama. H.,Fujio. Y.
- Organizer
  18th World Congress of Basic And Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02603
[Presentation] 腎線維化病態における転写因子OASISの役割2017
- Author(s)
  守沖瞳、尾花理徳、山本彩葉、金本聡自、前田真貴子、今泉和則、中山博之、藤尾慈
- Organizer
  第132回　日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-15K08232
[Presentation] Moesinは実験的自己免疫性心筋炎モデルにおいて活性化し、仮足形成を伴う組織修復に関与する(Moesin is activated in cardiomyocytes in experimental autoimmune myocarditis and mediates tissue restoration with protrusion formation)2017
- Author(s)
  Yusuke Mitsuhara, Akimitsu Miyawaki, Aya Orimoto, Yusuke Nakayasu, Shin-ichi Tsunoda, Masanori Obana, Makiko Maeda, Hiroyuki Nakayama, Yasuo Yoshioka, Yasuo Tsutsumi, Yasushi Fujio
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール
- Data Source
  KAKENHI-PROJECT-15K08232
[Presentation] 骨髄細胞特異的Runx2の欠損は心筋梗塞後の心筋リモデリングを悪化させる2017
- Author(s)
  芦塚萌　熊谷渉平　柳瀬絵美子　松本浩太朗　尾花理徳　前田真貴子　中山博之　藤尾慈
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎県長崎市
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] Safety and feasibility report of investigational therapy with interleukin-11 against acute myocardial infarction2017
- Author(s)
  Maeda, M., Nakagawa, M., Owada, Y., Izumi, Y., Nonin, S., Sugioka, K., Nakatani, D., Iwata,S., Mizutani, K., Nishimura, S., Ito, A., Fujita, S., Daimon, T., Sawa, Y., Asakura, M., Fujio, Y., Yoshiyama, M.
- Organizer
  American Heart Association Scientific Sessions 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08232
[Presentation] Moesinは実験的自己免疫性心筋炎モデルにおいて活性化し、仮足形成を伴う組織修復に関与する2017
- Author(s)
  密原佑介　宮脇昭光　折本彩　中安祐介　角田慎一　尾花理徳　前田真貴子　中山博之　吉岡靖雄　堤康央　藤尾慈
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎県長崎市
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] 心筋炎回復過程における心筋細胞の内因性増殖機構の解析2017
- Author(s)
  折本彩、中安佑介、松井理紗、宮脇昭光、尾花理徳、前田真貴子、中山博之、藤尾慈
- Organizer
  第132回　日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-15K08232
[Presentation] Myofibroblast-specific deletion of Runx2 improves systolic function and survival in late phase of cardiac remodeling after myocardial infarction2017
- Author(s)
  Tanaka, S., Enomoto, D., Yanase, E., Kumagi, S., Obana, M., Maeda, M., Fujio, Y., Nakayama, H.
- Organizer
  AHA Scientific Sessions 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08232
[Presentation] eIF4Bは、Pim-1キナーゼの下流における心筋細胞保護因子である2017
- Author(s)
  横山由加里　松本浩太朗　木下真希　尾花理徳　前田真貴子　中山博之　藤尾慈
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール
- Data Source
  KAKENHI-PROJECT-15K08232
[Presentation] 急性心筋梗塞に対するヒトIL-11製剤を用いた心筋保護治療2017
- Author(s)
  藤尾慈、前田真貴子、大門貴志、中谷大作、杉岡憲一、岩田真一、澤芳樹、朝倉正紀、泉康雄、葭山稔
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎県長崎市
- Year and Date
  2017-03-15
- Invited
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] RORgammatのヘテロ欠損は心筋梗塞後の心筋リモデリングを悪化させる2017
- Author(s)
  榎本大智　尾花理徳　松本浩太朗　前田真貴子　中山博之　藤尾慈
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎県長崎市
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] RORγtのヘテロ欠損は心筋梗塞後の心筋リモデリングを悪化させる（RORγt heterozygous deficiency aggravates cardiac remodeling after myocardial infarction）2017
- Author(s)
  Enomoto D, Obana M, Matsumoto K, Maeda M, Nakayama H, Fujio Y.
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール
- Data Source
  KAKENHI-PROJECT-15K08232
[Presentation] 急性心筋梗塞に対するヒトIL-11製剤を用いた心筋保護治療（Interleukin-11 therapy for cardioprotection against acute myocardial infarction)2017
- Author(s)
  藤尾慈、前田真貴子、大門貴志、中谷大作、杉岡憲一、岩田真一、澤芳樹、朝倉正紀、泉康雄、葭山稔
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール
- Data Source
  KAKENHI-PROJECT-15K08232
[Presentation] eIF4Bは、Pim-1キナーゼの下流における心筋細胞保護因子である2017
- Author(s)
  横山由加里　松本浩太朗　木下真希　尾花理徳　前田真貴子　中山博之　藤尾慈
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎県長崎市
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] Fibroblast-specific beta2 adrenergic receptor signaling regulates cardiac hypertrophy in mice.2016
- Author(s)
  Kota Tonegawa, Shota Tanaka, Misato Takahashi, Shota Fuchigami, Masanori Obana, Makiko Maeda, Yasushi Sakata, Yasushi Fujio, Hiroyuki Nakayama
- Organizer
  American Heart Association 2016 Scientific Sessions
- Place of Presentation
  New Orleans
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15052
[Presentation] Adult mammalian hearts restore intrinsic regenerative capacity through signal transducer and activator of transcription 3 in the resolution phase of myocarditis.2016
- Author(s)
  Miyawaki, A., Obana, M., Mitsuhara, Y., Orimoto, A., Nakayasu, Y., Yamashita, T., Fukada, S., Maeda, M., Sakata, Y., Nakayama, H., Fujio, Y.
- Organizer
  American Heart Association Scientific Sessions
- Place of Presentation
  New Orleans. USA.
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] Heterozygous ablation of RORγt gene deteriorates adverse cardiac remodeling after myocardial infarction.2016
- Author(s)
  Enomoto, D., Obana, M., Matsumoto, K., Sakata, Y., Maeda, M., Nakayama, H., Fujio, Y.
- Organizer
  American Heart Association Scientific Sessions
- Place of Presentation
  New Orleans. USA.
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] Heterozygous ablation of RORγt gene deteriorates adverse cardiac remodeling after myocardial infarction2016
- Author(s)
  Daichi Enomoto, Masanori Obana, Kotaro Matsumoto, Yasushi Sakata, Makiko Maeda, Hiroyuki Nakayama, Yasushi Fujio
- Organizer
  American Heart Association 2016 Scientific Sessions
- Place of Presentation
  New Orleans
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15052
[Presentation] Adult mammalian hearts restore intrinsic regenerative capacity through signal transducer and activator of transcription 3 in the resolution phase of myocarditis.2016
- Author(s)
  Akimitsu Miyawaki, Masanori Obana, Yusuke Mitsuhara, Aya Orimoto, Yusuke Nakayasu, Tomomi Yamashita, So-ichiro Fukada, Makiko Maeda, Yasushi Sakata, Hiroyuki Nakayama, Yasushi Fujio
- Organizer
  American Heart Association Scientific Session 2016
- Place of Presentation
  New Orleans.USA
- Data Source
  KAKENHI-PROJECT-15K08232
[Presentation] Heterozygous ablation of RORγt gene deteriorates adverse cardiac remodeling after myocardial infarction2016
- Author(s)
  Daichi Enomoto, Masanori Obana, Kotaro Matsumoto, Yasushi Sakata, Makiko Maeda, Hiroyuki Nakayama, Yasushi Fujio
- Organizer
  American Heart Association Scientific Session 2016
- Place of Presentation
  New Orleans.USA
- Data Source
  KAKENHI-PROJECT-15K08232
[Presentation] Myeloid cell-specific Runx2 deficiency exacerbates adverse cardiac remodeling after myocardial infarction2016
- Author(s)
  Moe Ashizuka,　Shohei Kumagai, Emiko Yanase, Masanori Obana,　Makiko Maeda, Yasushi Sakata, Hiroyuki Nakayama, Yasushi Fujio
- Organizer
  American Heart Association 2016 Scientific Sessions
- Place of Presentation
  New Orleans
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15052
[Presentation] Myeloid cell-specific Runx2 deficiency exacerbates adverse cardiac remodeling after myocardial infarction.2016
- Author(s)
  Ashizuka, M.,　Kumagai, S., Yanase, E., Obana, M.,　Maeda, M., Sakata, Y., Nakayama, H., Fujio, Y.
- Organizer
  American Heart Association Scientific Sessions
- Place of Presentation
  New Orleans. USA.
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] Pim-1を介したSTAT3による新規細胞保護機構の解明2016
- Author(s)
  大谷勇太、横山由加里、尾花理徳、前田真貴子、中山博之、藤尾慈
- Organizer
  日本薬学会136回
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K08232
[Presentation] 心筋炎病態下におけるSTAT3を介した成体心筋細胞増殖2016
- Author(s)
  宮脇昭光　高家圭紀　密原佑介　山下朋美　尾花理徳　前田真貴子　中山博之　藤尾慈
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜　パシフィコ横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] Adult Mammalian Hearts Restore Intrinsic Regenerative Capacity through Signal Transducer and Activator of Transcription 3 in the Resolution Phase of Myocarditis2016
- Author(s)
  Akimitsu Miyawaki, Masanori Obana, Yusuke Mitsuhara, Aya Orimoto, Yusuke Nakayasu, Tomomi Yamashita, So-ichiro Fukada, Makiko Maeda, Yasushi Sakata, Hiroyuki Nakayama, Yasushi Fujio.
- Organizer
  American Heart Association 2016 Scientific Sessions
- Place of Presentation
  New Orleans
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15052
[Presentation] Fibroblast-specific beta2 adrenergic receptor signaling regulates cardiac hypertrophy in mice.2016
- Author(s)
  Tonegawa, K., Tanaka, S., Takahashi, M., Fuchigami, S., Obana, M., Maeda, M., Sakata, Y., Fujio, Y,. Nakayama, H.
- Organizer
  American Heart Association Scientific Sessions
- Place of Presentation
  New Orleans. USA.
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] 心筋炎病態下におけるSTAT3を介した成体心筋細胞増殖2016
- Author(s)
  宮脇昭光　高家圭紀　密原佑介　山下朋美　尾花理徳　前田真貴子　中山博之　藤尾慈
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K08232
[Presentation] Myeloid Cell Derived Leucine Rich α2 Glycoprotein Attenuates Adverse Cardiac Remodeling After Myocardial Infarction.2015
- Author(s)
  4.Kumagai S, Nakayama H, Fujimoto M, Honda H, Serada S, Kasai A, Obana M, Sakata Y, Sawa Y, Naka T, Fujio Y
- Organizer
  American Heart Association Scientific Session 2015
- Place of Presentation
  米国オーランド
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15052
[Presentation] Blockade of NKG2D/NKG2D Ligands Interaction Attenuated Cardiac Remodeling after Myocardial Infarction2015
- Author(s)
  Kotaro Matsumoto, Masanori Obana, Rina Hashidzume, Yukari Yokoyama,Nakayama, Shigeru Miyagawa, Tomomi Mohri, Makiko Maeda, Yasushi Sakata, Hiroyuki Nakayama, Yoshiki Sawa, Yasushi Fujio
- Organizer
  American Heart Association Scientific Sessions 2015
- Place of Presentation
  Orlando
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] Blockade of NKG2D / NKG2D Ligands Interaction Attenuated Cardiac Remodeling After Myocardial Infarction.2015
- Author(s)
  2.Matsumoto K, Obana M, Hashizume R, Yokoyama Y, Miyagawa S, Mohri T, Maeda M, Nakayama H, Sawa Y, Fujio Y.
- Organizer
  American Heart Association Scientific Session 2015
- Place of Presentation
  米国オーランド
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15052
[Presentation] Myeloid Cell Derived Leucine Rich α2 Glycoprotein Attenuates AdverseCardiac Remodeling After Myocardial Infarction.2015
- Author(s)
  Shohei Kumagai, Hiroyuki Nakayama, Minoru Fujimoto, Hiromi Honda, Satoshi Serada, Atsushi Kasai, Masanori Obana, Yasushi Sakata, Yoshiki Sawa, Tetsuji Naka, Yasushi Fujio
- Organizer
  American Heart Association Scientific Sessions 2015
- Place of Presentation
  Ｏｒｌａｎｄｏ
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] Cardiac STAT3 activation in subacute phase of myocardial infarction was required for the suppression of adverse cardiac remodeling2015
- Author(s)
  Enomoto, D., Obana, M., Miyawaki, A., Maeda, m., Nakayama,H., Fujio, Y.
- Organizer
  American Heart Association Scientific Sessions 2015
- Place of Presentation
  Orlando
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08232
[Presentation] Gp130サイトカインと心血管病2015
- Author(s)
  藤尾　慈、前田真貴子、朝倉正紀、中谷大作、泉　康雄、葭山　稔
- Organizer
  第1回、国際心血管薬物療法学会日本部会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-15K08232
[Presentation] ｇｐ130サイトカインと心血管病2015
- Author(s)
  藤尾　慈、前田真貴子、朝倉正紀、中谷大作、泉　康雄、葭山　稔
- Organizer
  第1回国際心血管薬物療法学会日本部会
- Place of Presentation
  京都　ハイアットリージェンシー京都
- Year and Date
  2015-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] Adrenergic Receptors β2 and β3 Transduce Differential Signals in Cardiac Fibroblasts.2015
- Author(s)
  3.Tonegawa K, Nakayama H, Igarashi H, Matsunami S, Hayamizu N, Obana M, Maeda M, Fujio Y.
- Organizer
  American Heart Association Scientific Session 2015
- Place of Presentation
  米国オーランド
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15052
[Presentation] Cardiac STAT3 Activation in Subacute Phase of Myocardial Infarction was Required for the Suppression of Adverse Cardiac Remodeling.2015
- Author(s)
  1.Enomoto D, Obana M, Miyawaki A, Mohri T, Maeda M, Sakata Y, Nakayama H, Fujio Y.
- Organizer
  American Heart Association Scientific Session 2015
- Place of Presentation
  米国オーランド
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15052
[Presentation] Cardiac STAT3 activation in subacute phase of myocardial infarction was required for the suppression of adverse cardiac remodeling2015
- Author(s)
  Daichi Eonomoto, Masanori Obana, Akimitsu Miyawaki, Makiko Maeda, Hiroyuki Nakayama, Yasushi Fujio
- Organizer
  American Heart Association Scientific Sessions 2015
- Place of Presentation
  Orlando
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] マクロファージ特異的なCD93過剰発現による死細胞貪食の増強は心筋梗塞後の心筋線維化を抑制する2014
- Author(s)
  竹脇佳那，山下朋美，宮本香織，毛利友美，中山博之，藤尾慈
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] BIN1の過剰発現は心筋細胞死を介して心筋リモデリングを増悪する2014
- Author(s)
  舎川洸太，松浪佐知，土山大介，中山博之，藤尾慈
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] マクロファージ特異的なCD93過剰発現による死細胞貪食の増強は心筋梗塞後の心筋線維化を抑制する2014
- Author(s)
  竹脇佳那，山下朋美，宮本香織，毛利友美，中山博之，藤尾慈
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25670193
[Presentation] 心疾患におけるgp130サイトカインの役割：新たな治療法の開発を目指して2014
- Author(s)
  藤尾　慈、葭山　稔
- Organizer
  日本薬学会134年年会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Excessive BIN1 expression results in adeverse remodeling through cardiomyocyte death2014
- Author(s)
  Kota Tonegawa, Sachi Matsunami, Daisuke Tsuchiyama, Hiroyuki Nakayama, Yasushi Fujio
- Organizer
  日本薬理学会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-23390212
[Presentation] L 型カルシウムチャネルβ2a サブユニットのリン酸化は心筋細胞肥大を惹起する2014
- Author(s)
  早水菜穂, 熊谷渉平, 松浪佐知, 中山博之, 藤尾慈
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] L型カルシウムチャネルβ2aサブユニットのリン酸化は心筋細胞肥大を惹起する2014
- Author(s)
  早水菜穂，熊谷渉平，松浪佐知，中山博之，藤尾慈
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Caveolae-specific phosphorylation of L-type calcium channel 2a subunit exaggerates cardiac hypertrophic responses after 1 adrenergic stimulation in mice.2014
- Author(s)
  Hiroyuki Nakayama, Shohei Kumagai, Sachi Matsunami, Nao Hayamizu Wataru Otsuka and Yasushi Fujio.
- Organizer
  Basic Cardiovascular Sciences/American Heart Association
- Place of Presentation
  Paris Las Vegas (ラスベガス）
- Data Source
  KAKENHI-PROJECT-23390212
[Presentation] BIN1 の過剰発現は心筋細胞死を介して心筋リモデリングを増悪する2014
- Author(s)
  舎川洸太, 松浪佐知, 土山大介, 中山博之, 藤尾慈
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] L型カルシウムチャネルβ2aサブユニットのリン酸化は心筋細胞肥大を惹起する2014
- Author(s)
  早水菜穂，熊谷渉平，松浪佐知，中山博之，藤尾慈
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25670193
[Presentation] マクロファージ特異的なCD93 過剰発現による死細胞貪食の増強は心筋梗塞後の心筋線維化を抑制する2014
- Author(s)
  竹脇佳那, 山下朋美, 宮本香織, 毛利友美, 中山博之, 藤尾慈
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] 心疾患におけるgp130 サイトカインの役割 : 新たな治療法の開発を目指して2014
- Author(s)
  藤尾慈, 葭山稔
- Organizer
  日本薬学会134会年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Phosphorylation of L-type Ca2+ channel b2a subunit induces cardiomyocyte hypertrophy2014
- Author(s)
  Nao Hyamizu, Shohei Kumagai, Sachi Matsunami, Hiroyuki Nakayama, Yasushi Fujio
- Organizer
  日本薬理学会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-23390212
[Presentation] 心疾患におけるgp130サイトカインの役割：新たな治療法の開発を目指して2014
- Author(s)
  藤尾　慈、葭山　稔
- Organizer
  日本薬学会134会年会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-25670193
[Presentation] BIN1の過剰発現は心筋細胞死を介して心筋リモデリングを増悪する2014
- Author(s)
  舎川洸太，松浪佐知，土山大介，中山博之，藤尾慈
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25670193
[Presentation] Inhibition of P2X7 Receptor Signaling Promotes Adverse Cardiac Remodeling after Myocardial Infarction through Enhanced Cardiac Fibroblast Migration2013
- Author(s)
  Kumagai Shohei, Nakayama Hiroyuki, Miyawaki Akimitsu, Mohri Tomomi, Fujio Yasushi,
- Organizer
  American Heart Association
- Place of Presentation
  ダラス
- Data Source
  KAKENHI-PROJECT-23390212
[Presentation] マクロファージによる死細胞貪食は心筋梗塞後の病態形成を抑制する2013
- Author(s)
  竹脇佳那, 宮本香織, 尾花理徳, 山下朋美, 毛利友美, 中山博之, 藤尾慈
- Organizer
  第124回日本薬理学会近畿部会
- Place of Presentation
  京都
- Year and Date
  2013-11-01
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] A report From the Japanese pharmacogenomics clinical trial; CYP2A6 Gene Polymorphisms Influence Nicotine Dependence and Monoamine Oxidase Gene Polymorphism Does Smoking Cessation Behavior2013
- Author(s)
  Makiko Maeda, Yaushi Fujio, Yasuhiko Takemoto, Junichi Azuma
- Organizer
  American Heart Association Scientific Sessions 2013
- Place of Presentation
  Dallas, Texas, USA
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] CD4+CD25+ regulatory T cells (Treg cells) migrate into hearts in experimental autoimmune myocarditis (EAM)2013
- Author(s)
  鳥居里衣, 山下朋美, 古谷知佳, 中山博之, 藤尾慈
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Inhibition of P2X7 Receptor Signaling Promotes Adverse Cardiac Remodeling after Myocardial Infarction through Enhanced Cardiac Fibroblast Migration2013
- Author(s)
  Shohei Kumagai, Hiroyuki Nakayama, Akimitsu Miyawaki, Tomomi Mohri, Yasushi Fujio
- Organizer
  American Heart Association Scientific Sessions 2013
- Place of Presentation
  Dallas, Texas, USA
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] A report From the Japanese pharmacogenomics clinical trial; CYP2A6 Gene Polymorphisms Influence Nicotine Dependence and Monoamine Oxidase Gene Polymorphism Does Smoking Cessation Behavior2013
- Author(s)
  Makiko Maeda, Yaushi Fujio, Yasuhiko Takemoto, Junichi Azuma
- Organizer
  The American Heart Association Scientific Sessions 2013
- Place of Presentation
  Dallas, Texas, USA
- Data Source
  KAKENHI-PROJECT-25670193
[Presentation] A report from the Japanese pharmacogenomics clinical trial; CYP2A6 Gene Polymorphisms Influence Nicotine Dependence and Monoamine Oxidase Gene Polymorphism Does Smoking Cessation Behavior2013
- Author(s)
  Maeda, M., Fujio, Y., Takemoto, Y., Azuma, J
- Organizer
  The American Heart Association Scientific Sessions 2013
- Place of Presentation
  Dallas, Texas, USA
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Inhibition of P2X7 Receptor Signaling Promotes Adverse Cardiac Remodeling after Myocardial Infarction through Enhanced Cardiac Fibroblast Migration2013
- Author(s)
  Shohei Kumagai, Hiroyuki Nakayama, Akimitsu Miyawaki, Tomomi Mohri, Yasushi Fujio
- Organizer
  The American Heart Association Scientific Sessions 2013
- Place of Presentation
  Dallas, Texas, USA
- Data Source
  KAKENHI-PROJECT-25670193
[Presentation] The myocardial activation of CaMKIIβ leads to heart failure2013
- Author(s)
  輪島こまゆ, 中山博之, 濱谷辰斗, 松浪佐知, 熊谷渉平, 山下朋美, 藤尾慈
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Development of a novel tool for analysis of PKA and CaMKII activities in caveolae microdomain2013
- Author(s)
  松浪佐知, 早水菜穂, 中山博之, 藤尾慈
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Deficiency of P2X7 receptor signaling promotes adverse cardiac remodeling after myocardial infarction through enhanced cardiac fibroblast migration2013
- Author(s)
  熊谷渉平, 中山博之, 宮脇昭光, 毛利友美, 藤尾慈
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] 心血管病におけるサイトカイン医科学-gp130サイトカインと心筋保護2013
- Author(s)
  藤尾　慈
- Organizer
  生体機能と創薬シンポジウム2013
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-25670193
[Presentation] 心血管病におけるサイトカイン医科学-gp130サイトカインと心筋保護2013
- Author(s)
  藤尾　慈
- Organizer
  生体機能と創薬シンポジウム2013
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] 急性心筋梗塞に対するインターロイキン11 (IL-11)製剤を用いた心筋保護治療の臨床試験のためのプロトコール作成研究2013
- Author(s)
  大和田康子, 泉康雄, 朝倉正紀, 山本晴子, 前田真貴子, 葭山稔, 藤尾慈
- Organizer
  第34回日本臨床薬理学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Cathelicidin antimicrobial peptide inhibits fibroblasts migration via P2X7 receptor signaling2013
- Author(s)
  熊谷渉平, 中山博之, 松井一樹, 川口晴世, 宮脇昭光, 山下朋美, 藤尾慈
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Regulatory T cells (Tregs) ameliorate myocardial infarction (MI)-induced cardiac remodeling in mice2013
- Author(s)
  多賀詩織, 山下朋美, 中山博之, 藤尾慈
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] 心血管病におけるサイトカイン医科学---gp130 サイトカインと心筋保護2013
- Author(s)
  藤尾慈
- Organizer
  生体機能と創薬シンポジウム2013
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Inhibition of P2X7 receptor signaling promotes adverse cardiac remodeling after myocardial infarction through enhanced cardiac fibroblast migration2013
- Author(s)
  熊谷渉平　中山博之　宮脇昭光　毛利友美　藤尾慈
- Organizer
  日本血管生物医学会
- Place of Presentation
  千里国際阪急ホテル（大阪）
- Data Source
  KAKENHI-PROJECT-23390212
[Presentation] ニコチン代謝酵素CYP2A6遺伝子多型と呼気CO 濃度の関係2013
- Author(s)
  前田真貴子, 杉浦知佳, 志賀遼大, 松岡翔太, 竹ノ内拓也, 中西和親, 山川剛, 藤尾慈, 東純一
- Organizer
  第34回日本臨床薬理学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Inhibition of P2X7 Receptor Signaling Promotes Adverse Cardiac Remodeling after Myocardial Infarction through Enhanced Cardiac Fibroblast Migration2013
- Author(s)
  Kumagai, S., Nakayama, H., Miyawaki, A., Mohri, T., Fujio, Y
- Organizer
  The American Heart Association Scientific Sessions 2013
- Place of Presentation
  Dallas, Texas, USA
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] 虚血再灌流障害に対するIL-11 のpost-conditioning 効果は心筋STAT3 を介する2012
- Author(s)
  宮本香織, 尾花理徳, 前田真貴子, 中山博之, 藤尾慈
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Interleukin-11 exhibits thePost-conditioning Effects against Ischemia Reperfusion injury via Cardiac Signal Transducer and Activator of Transcription 3.2012
- Author(s)
  Kaori Miyamoto, Masanori Obana, Makiko Maeda, Hiroyuki Nakayama, Yasushi Fujio
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-22590160
[Presentation] The ablation of RORγt gene results in advanced cardiac fibrosis after myocardial infarction2012
- Author(s)
  山下朋美, 尾花理徳, 端山明子, 中山博之, 藤尾慈
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Treg is Recruited into Myocardium through Th17 Pathway as a Negative Feedback in Autoimmune Myocarditis2012
- Author(s)
  Yamashita, T., Torii, R., Komuro, I., Nakayama, H., Fujio, Y
- Organizer
  The American Heart Association Scientific Sessions 2012
- Place of Presentation
  Los Angeles, California, USA
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] 実験的自己免疫性心筋炎におけるTSG-6 の役割の検討2012
- Author(s)
  川口晴世, 山下朋美, 鳥居里衣, 中山博之, 藤尾慈
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] 心筋特異的Runx2 過剰発現マウスは心肥大を惹起する2012
- Author(s)
  濱谷辰斗, 中山博之, 松浪佐知, 松尾玲男, 藤尾慈
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Cardiac-specific Overexpression of Runx2 Mediates Cardiac Hypertrophy and Dysfunction in Mice2012
- Author(s)
  Nakayama, H., Hamatani, T., Kumagai, S., Tonegawa, K., Yamashita, T., Fujio, Y
- Organizer
  Basic Cardiovascular Sciences 2012 Scientific Sessions
- Place of Presentation
  New Orleans, Louisiana, USA
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Interleukin-11 Attenuates Infarct Size And Improves Ventricular Function In a Canine Heart Model Of Ischemia/Reperfusion Injury.2012
- Author(s)
  Makiko Maeda, Koji Takeda, Goro Matsumiya, Junichi Azuma, Yasushi Fujio
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-22590160
[Presentation] Cathelicidin Antimicrobial Peptide Is Upregulated after Myocarditis and Inhibits Fibroblast Migration via P2x7 Receptor Signaling2011
- Author(s)
  Nakayama, H., Matsui, K., Yamashita, T., Kawaguchi, H., Fujio, Y
- Organizer
  Basic Cardiovascular Sciences 2011 Scientific Sessions
- Place of Presentation
  New Orleans, Louisiana, USA
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Th17 Cells Are Indispensable for Cardiac Inflammation in Autoimmune Myocarditis2011
- Author(s)
  Yamashita, Nakayama, H., Fujio, Y
- Organizer
  Basic Cardiovascular Sciences 2011 Scientific Sessions
- Place of Presentation
  New Orleans, Louisiana, USA
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] Th17 Cells Exhibit Protective Effects against Cardiac Fibrosis after Myocardial Infarction2011
- Author(s)
  Yamashita, T., Obana, M., Hayama, A., Iwakura, T., Komuro, I., Nakayama, H., Fujio, Y
- Organizer
  The American Heart Association Scientific Sessions 2011
- Place of Presentation
  Orlando, Florida, USA
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] 喫煙による薬物代謝酵素UGT1A1誘導に対する核内レセプターCAR 及びAhR の関与2011
- Author(s)
  志賀遼大, 杉浦知佳, 前田真貴子, 東純一, 藤尾慈
- Organizer
  第32回日本臨床薬理学会年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] 虚血再灌流傷害におけるIL-11のpost-conditioning効果について2011
- Author(s)
  宮本香織、尾花理徳、前田真貴子、東純一、中山博之、藤尾慈
- Organizer
  第118回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター(大阪)
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-22590160
[Presentation] Cathelicidin antimicrobial peptide is up-regulated after myocarditis and inhibits fibroblasts migration via P2X7 receptor signaling2011
- Author(s)
  中山博之, 松井一樹, 川口晴世, 藤尾慈
- Organizer
  第2回Molecular Cardiovascular Conference II
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-23390057
[Presentation] 虚血再灌流傷害におけるIL-11のpost-conditioning効果について2010
- Author(s)
  宮本香織、尾花理徳、前田真貴子、東純一、中山博之、藤尾慈
- Organizer
  第118回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター(大阪)
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22590160
[Presentation] Osteopontin遺伝子プロモーター多型と高血圧患者における左室拡張機能障害の関連2010
- Author(s)
  長井裕美、東純一、藤尾慈
- Organizer
  日本臨床薬理学会
- Place of Presentation
  京都
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-20590834
[Presentation] 喫煙による薬物代謝酵素CYP2B6誘導に対する核内レセプターCARの関与2010
- Author(s)
  志賀遼太、前田真貴子、藤尾慈、東純一
- Organizer
  日本臨床薬理学会
- Place of Presentation
  京都
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-20590834
[Presentation] Pim-1 kinase is required for endothelial differentiation of cardiac stem cells via STAT3 signaling pathway2010
- Author(s)
  Tomohiko Iwakura, Tomomi Mohri, Tomomi Yamashita, Masanori Obana, Akiko Hayama, Makiko Maeda, Hiroyuki Nakayama, Issei Komuro, Junichi Azuma, Yasushi Fujio
- Organizer
  The American Heart Association Scientific Sessions
- Place of Presentation
  Chicago, Illinois, USA
- Year and Date
  2010-11-07
- Data Source
  KAKENHI-PROJECT-22590160
[Presentation] ニコチン代謝酵素CYP2A6遺伝子多型のニコチン依存強度に与える影響2009
- Author(s)
  杉浦知佳、前田真貴子、竹本恭彦、藤尾慈、東純一
- Organizer
  日本臨床薬理学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-20590834
[Presentation] Drug Dosing Considerations for Antithrombotic Therapy2009
- Author(s)
  Fujio, Y.
- Organizer
  Session : Joint AHA/Asian Pacific Society of Cardiology : Pharmacogenomics : Implications for Drug Dosing and Clinical Trials in Different Populations. American Heart Association, Scientific Session 2009
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-20390069
[Presentation] Combined genotype of norepinephrine transporter T-182C and alpha2c adrenergic receptor deletion polymorphisms is associated with the response to beta-blockers in dilated cardiomyopathy2008
- Author(s)
  Nonen, S., Fujio, Y., Takemoto, Y., Yoshiyama, M., Azuma, J.
- Organizer
  World Conference on Clinical Pharmacology and Therapeutics
- Place of Presentation
  Quebec, Canada
- Year and Date
  2008-07-28
- Data Source
  KAKENHI-PROJECT-20590834
[Presentation] The Association of Osteopontin with Cardiac Fibrosis and the Responsiveness to Beta-blockers in Patients with Heart Failure2008
- Author(s)
  Okamoto, H., Fujio, Y., Takemoto, Y., Yoshiyama, M., Azuma, J.
- Organizer
  American Heart Association
- Place of Presentation
  New Orleans, USA
- Year and Date
  2008-11-11
- Data Source
  KAKENHI-PROJECT-20590834
[Presentation] Combined genotype of norepinephrine transporter T-182C and alpha2c adrenergic receptor deletion polymorphisms is associated with the response to beta-blockers in dilated cardiomyopathy2008
- Author(s)
  Nonen, S., Fujio, Y., Takemoto, Y., Yoshiyama, M., Azuma, J.
- Organizer
  薬理学・臨床薬理学共催シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-12-20
- Data Source
  KAKENHI-PROJECT-20590834
[Presentation] 心不全治療におけるβ遮断薬反応性の個人差とThrombospondn1遺伝子多型との関連2008
- Author(s)
  上野由香子、藤尾慈、竹本恭彦、葭山稔、東純一
- Organizer
  日本臨床薬理学会
- Place of Presentation
  東京
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-20590834
[Presentation] Complement component 4遺伝子コピー数多型と拡張型心筋症による心不全治療におけるβ遮断薬反応性個人差との関連2008
- Author(s)
  松本恭尚、藤尾慈、竹本恭彦、葭山稔、東純一
- Organizer
  日本臨床薬理学会
- Place of Presentation
  東京
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-20590834
[Presentation] Thrombospondin 1 polymorphism(Thr523Ala) is associated with the response toβ-blockers in the patients with dilated cardiomyopathy2008
- Author(s)
  Nonen, S., Fujio, Y., Takemoto, Y., Yoshiyama, M., Azuma, J.
- Organizer
  次世代シンポジウム
- Place of Presentation
  京都
- Year and Date
  2008-12-20
- Data Source
  KAKENHI-PROJECT-20590834
[Presentation] 心不全におけるβ遮断薬反応性関連バイオマーカーとしてのオステオポンチン遺伝子多型性の意義2008
- Author(s)
  岡本洋、藤尾慈、竹本恭彦、東純一
- Organizer
  日本オステオポンチン研究会
- Year and Date
  2008-09-27
- Data Source
  KAKENHI-PROJECT-20590834
[Presentation] Cytokine2008
- Author(s)
  Fujio, Y.
- Organizer
  American Heart AssociationScientific Session
- Place of Presentation
  New Orleans
- Year and Date
  2008-11-11
- Data Source
  KAKENHI-PROJECT-20390069
[Presentation] Cytokine Session : How to Recognize Cell Death and Its Impact on Heart Failure American Heart Association2008
- Author(s)
  Fujio, Y.
- Organizer
  Scientific Session 2008
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-20390069
[Presentation] 血小板減少症治療薬インターロイキン(IL)-11を用いた心不全に対するサイトカイン療法II -慢性モデルを用いた検討-2007
- Author(s)
  藤尾慈, ら
- Organizer
  第28回日本臨床薬理学会年会
- Place of Presentation
  宇都宮
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390065
[Presentation] Signals Through Glycoprotein 130 Promote the Endothelial Differentiation of Cardiac Sca-1+ Cells2007
- Author(s)
  Tomomi, Mohri, Yasushi, Fujio, Tomohiko, Iwakura, et. al.
- Organizer
  The American Heart Association Scientific Sessions 2007
- Place of Presentation
  Orlando, Florida, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390065
[Presentation] 【シンポジウム】"新しい心不全評価法:心臓超音波検査・核医学検査・バイオマーカーを中心として"Cytokine Signaling and its Clinical Implications in Heart Failure.2007
- Author(s)
  藤尾慈, 東純一
- Organizer
  第11回日本心不全学会学術集会
- Place of Presentation
  千葉県浦安
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390065
[Presentation] Signals Through Glycoprotein 130 Promote the Endothelial Differentiation of Cardiac Sca-1+Cells2007
- Author(s)
  Mohri, T., Fujio, Y.
- Organizer
  American Heart Association Scientific Sessions 2007
- Place of Presentation
  Orlando, Florida, USA
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-16390065
[Presentation] Atrogin-1 Ubiquitin Ligase is Upregulated by Doxorubicin, Leading to Muscle Atrophy in Cardiac Myocytes.2006
- Author(s)
  Yasushi Fujio, et. al.
- Organizer
  The American Heart Association Scientific Sessions 2006
- Place of Presentation
  Chicago, Illinois, USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390065
[Presentation] Cardiac Sca-1+ Cells were Differentiated into Endothelial Cells by Leukemia Inhibitory Factor, a Paracrine Cytokine2006
- Author(s)
  Tomomi, Mohri, Yasushi, Fujio, Makiko, Maeda, et. al.
- Organizer
  The American Heart Association Scientific Sessions 2006
- Place of Presentation
  Chicago, Illinois, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390065
[Presentation] Interleukin(IL)-11 Prevents Ischemia/Reperfusion Injury in Hearts as a Novel Cardioprotective Cytokine2006
- Author(s)
  Makiko, Maeda, Yasushi, Fujio, Ryusuke, Kimura, et. al.
- Organizer
  The American Heart Association Scientific Sessions 2006
- Place of Presentation
  Chicago, Illinois, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390065
[Presentation] Atrogin-1 Ubiquitin Ligase is Upregulated by Doxorubicin, Leading to Muscle Atrophy in Cardiac Myocytes2006
- Author(s)
  Yasushi, Fujio, Yuki, Hoshino-Nariai, Yasuhiro, Yamamoto, et. al.
- Organizer
  The American Heart Association Scientific Sessions 2006
- Place of Presentation
  Chicago, Illinois, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390065
[Presentation] Leukemia inhibitory factor induces endothelial differentiation in cardiac Sca-1+ stem cells2006
- Author(s)
  Mohri, T, Fujio, Y, Maeda, M, et. al.
- Organizer
  The 15th World Congress of Pharmacology IUPHAR 2006
- Place of Presentation
  Beijing, China
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390065
[Presentation] Caveolae-specific phosphorylation of L-type calcium channel beta2a subunit excerbates cardiac hypertrophy
- Author(s)
  Shohei Kumagai, Hiroyuki Nakayama, Nao Hayamizu, Wataru Otsuka, Yasushi Fujio
- Organizer
  American Heart Association, Scientific Sessions 2014
- Place of Presentation
  Chicago, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] Adrenergic receptors β2 and β3 transduce differential signalsin cardiac fibroblasts.
- Author(s)
  五十嵐裕美、中山博之、松浪佐知、早水菜穂、舎川洸太、尾花理徳、前田真貴子、藤尾慈
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25670193
[Presentation] Caveolae-specific phosphorylation of L-type calcium channel b2a subunit exaggerates cardiac hypertrophic responses after a1 adrenergic stimulation in mice.
- Author(s)
  Nakayama, H., Kumagai, S., Matsunami, S., Hayamizu, N, Tonegawa, K., Otsuka, W., Fujio, Y.
- Organizer
  International Society of Heart Research 日本部会総会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-28 – 2014-11-29
- Data Source
  KAKENHI-PROJECT-25670193
[Presentation] Elucidation of molecular mechanism of cardiomyocyte necrosis induced by reactive oxygen species.
- Author(s)
  土山大介、中山博之、森原啓文、石田瑛子、尾花理徳、前田真貴子、藤尾慈
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] Adrenergic receptors β2 and β3 transduce differential signalsin cardiac fibroblasts.
- Author(s)
  五十嵐裕美、中山博之、松浪佐知、早水菜穂、舎川洸太、尾花理徳、前田真貴子、藤尾慈
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] The properties of cardiac Sca-1+ resident stem cells are altered in response to myocardial inflammation.
- Author(s)
  松原由実、宮脇昭光、榎原正貴、尾花理徳、前田真貴子、中山博之、藤尾慈
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] Interleukin 27 induces endothelial differentiation in murine cardiac stem cells.
- Author(s)
  田中智大、尾花理徳、前田真貴子、中山博之、藤尾慈
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25670193
[Presentation] Caveolae-specific phosphorylation of L-type calcium channel b2a subunit exaggerates cardiac hypertrophic responses after a1 adrenergic stimulation in mice
- Author(s)
  Hiroyuki Nakayama, Shohei Kumagai, Sachi Matsunami, Nao Hayamizu, Kota Tonegawa, Wataru Otsuka, Yasushi Fujio
- Organizer
  International Society of Heart Research 日本部会総会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-28 – 2014-11-29
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] IL-27 negatively regulates murine experimental autoimmune myocarditis (EAM).
- Author(s)
  古谷知佳、宮脇昭光、大谷勇太、尾花理徳、前田真貴子、中山博之、藤尾慈
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] Administration of phospholamban-antisense locked nucleic acid improves cardiac contractility in a murine heart failure model
- Author(s)
  森原啓文, 中山博之, 大岩晴矩, 土山大介, 山本剛史, 小比賀聡, 藤尾慈
- Organizer
  第18回日本心不全学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-10 – 2014-10-12
- Data Source
  KAKENHI-PROJECT-25670193
[Presentation] The properties of cardiac Sca-1+ resident stem cells are altered in response to myocardial inflammation.
- Author(s)
  松原由実、宮脇昭光、榎原正貴、尾花理徳、前田真貴子、中山博之、藤尾慈
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25670193
[Presentation] ニコチン性アセチルコリン受容体α4サブユニット遺伝子多型rs2273504とニコチン依存との関連について
- Author(s)
  前田真貴子、杉浦知佳、志賀遼太、藤尾慈、東純一
- Organizer
  第131回日本薬学会
- Place of Presentation
  静岡(東日本大震災のため開催中止)
- Data Source
  KAKENHI-PROJECT-22590160
[Presentation] Caveolae-specific phosphorylation of L-type calcium channel b2a subunit exaggerates cardiac hypertrophic responses after a1 adrenergic stimulation in mice.
- Author(s)
  Hiroyuki Nakayama, Shohei Kumagai, Sachi　Matsunami, Nao Hayamizu, Kota Tonegawa, Wataru Otsuka , Yasushi Fujio
- Organizer
  American Heart Association, Basic Cardiovascular Sciences
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2014-07-13 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] Elucidation of molecular mechanism of cardiomyocyte necrosis induced by reactive oxygen species.
- Author(s)
  土山大介、中山博之、森原啓文、石田瑛子、尾花理徳、前田真貴子、藤尾慈
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25670193
[Presentation] IL-27 negatively regulates murine experimental autoimmune myocarditis (EAM).
- Author(s)
  古谷知佳、宮脇昭光、大谷勇太、尾花理徳、前田真貴子、中山博之、藤尾慈
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25670193
[Presentation] Interleukin 27 induces endothelial differentiation in murine cardiac stem cells
- Author(s)
  田中智大、尾花理徳、前田真貴子、中山博之、藤尾慈
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26293054
[Presentation] The overexpression of CD93 in myeloid cells attenuated the cardiac fibrosis after myocardial infarction
- Author(s)
  大谷勇太、竹脇佳那、宮本香織、尾花理徳、中山博之、藤尾慈
- Organizer
  第18回日本心不全学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-10 – 2014-10-12
- Data Source
  KAKENHI-PROJECT-25670193

1. MAEDA Makiko (70461168)

# of Collaborated Projects: 8 results

# of Collaborated Products: 68 results
2. AZUMA Junichi (30144463)

# of Collaborated Projects: 7 results

# of Collaborated Products: 34 results
3. NAKAYAMA Hiroyuki (40581062)

# of Collaborated Projects: 5 results

# of Collaborated Products: 84 results
4. TAKEMOTO Yasuhiko (20364002)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. YOSHIYAMA Minoru (30240956)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. KOUNO Hiroki (40375803)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. MATSUMIYA Goro (20314312)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. ISHIDA Keiichi (40375671)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. Okada Yoshiaki (50444500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. 尾花理徳 (50745883)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
11. NAKAOKA Yoshikazu (90393214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. ASAHI Michio (10397614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HIROHASHI Kazuhiro (00145799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NONEN Shinpei (40467527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. ISHIZAKA Toru (10372616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KINOSHITA T (20186290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KATO M (00351510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. FUKUDA T (10423120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KURODA Etsushi (10299604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 川瀬一郎 (10161324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 吉田光弘 (90359844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 毛利友美 (20572960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. 仲哲治 (30303936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
24. 土井健史 (00211409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 櫻井文教 (70370939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 立花雅史 (80513449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. Aird William

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. HINO Nobumasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 深田宗一朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUJIO Yasushi 藤尾 慈

Research Projects

Research Products

Co-Researchers

心臓の恒常性維持/組織リモデリングおけるFibrocytesの意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and characterization of novel myeloid cells that infiltrate into post-infarct myocardiumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Characterization of diploid cardiomyocytes in adult mammalian heartsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of cell proliferation of adult mammalian cardiomyocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The molecular and cellular mechanism of myocardial repair/regenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immune surveillance is involved in cardiomyocyte death in diseased heartsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Myocardial inflammation of heart failure as a novel therapeutic targetPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

FUJIO Yasushi 藤尾慈