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Hirano Seiki  平野 世紀

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HIRANO SEIKI  平野 世紀

平野 世紀

HIRANO Seiki  平野 世紀

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Researcher Number 20368616
Other IDs
Affiliation (Current) 2025: 高知大学, 教育研究部医療学系臨床医学部門, 助教
Affiliation (based on the past Project Information) *help 2013: 高知大学, 教育研究部医療学系, 助教
2011 – 2012: 高知大学, 医学部附属病院, 医員
2009: 川崎医科大学, 医学研究科, 助手
2006: 川崎医大, 医学部, 助手
2003 – 2005: 川崎医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Kidney internal medicine / Pathological medical chemistry
Except Principal Investigator
Biological Sciences / General medical chemistry
Keywords
Principal Investigator
DNA修復 / 尿細管再生 / 細胞周期 / 急性腎障害 / 腎尿細管障害 / FAコア複合体 / 姉妹染色分体交換 / DNA鎖架橋剤 / Bloom症候群 / Fanconi貧血 … More
Except Principal Investigator
… More DNA修復 / DNA repair / 相同DNA組み換え / DT40細胞 / ファンコニ貧血 / protein transduction / estrogen receptor / DNA double strand break / I-Sce I / プロテイントランスダクション / TAT配列 / I-SceI / エストロジェン受容体 / TAT配 / I-Scel / DNA二重鎖切断 / sister chromatid exchanges / Fanconi anemia / Rad51 paralogs / DT 40 cells / homologous recombination / XRCC3 / Rad52 / Rad51ファミリー / Rad51 / 相同組み換え / 複製後修復 / ジーンターゲティング / 相同組替え / 姉妹染色分体交換 / BLMヘリケース / Rad51パラログ / FAコア複合体 / ゲノム安定性 / モノユビキチン化 / シスプラチン / ユビキチン化 / FANCI / FANCD2 / ゲノム不安定性 Less
  • Research Projects

    (5 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (8 People)
  •  Analysis of DNA repair, cell cycle progression and cell death in dedifferentiation and regeration of renal tubular cellsPrincipal Investigator

    • Principal Investigator
      HIRANO SEIKI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Kochi University
  •  Functional analysis of Fanconi anemia genes that are involved in chromosomal stability and tumor prevention

    • Principal Investigator
      TAKATA Minoru
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
      Hiroshima University
      Kawasaki Medical School
  •  Fanconi貧血原因遺伝子とBloomヘリケースのクロストークの解析Principal Investigator

    • Principal Investigator
      平野 世紀
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kawasaki Medical School
  •  Physical monitoring of repair process of chromosomal double stand break induced by simultaneous nuclear introduction of I-SceI endonuclease

    • Principal Investigator
      TAKATA Minoru
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Kawasaki Medical School
  •  Functional analysis of genes involved in maintenance of chromosome stability and homologous recombination

    • Principal Investigator
      TAKATA Minoru
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kawasaki Medical School

All 2011 2009 2007 2005 2004

All Journal Article Presentation

  • [Journal Article] Chemopreventive effects of gefitinib on nonsmoking-related lung tumori genesis in activating epidermal growth factor receptor transgenic mice2009

    • Author(s)
      Ohashi K, Takigawa N, Osawa M, Ichihara E, Takeda H, Kubo T, Hirano S, Yoshino T, Takata M, Tanimoto M, Kiura K.
    • Journal Title

      Can Res 69

      Pages: 7088-7095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] Chemopreventive effects of gefitinib on nonsmoking-related lung tumorigenesis in activating epidermal growth factor receptor transgenic mice.2009

    • Author(s)
      Ohashi K., Takigawa N., Osawa M., Ichihara E., Takeda H., Kubo T., Hirano S., Yoshino T., Takata M., animoto M., Kiura K.
    • Journal Title

      Cancer Res. 69

      Pages: 7088-7095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrving EGFR mutation.2007

    • Author(s)
      Uchida A, Hirano S, et al.
    • Journal Title

      Cancer science 98・3

      Pages: 357-363

    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] Emergence of Epidermal Growth Factor Receptor T790M Mutation during Chronic Exposure to Gefitinib in a Non Small Cell Lung Cancer Cell Line.2007

    • Author(s)
      Ogino A., Kitao H., A., Ishiai M., Kozuki T., Takigawa N., Hirano S., Uchida Takata M., Kiura K., Tanimoto M.
    • Journal Title

      Cancer Res. 67

      Pages: 7807-7014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] A requirement of FancL and FancD2 monoubiquitination in DNA repair.2007

    • Author(s)
      Seki S., Ohzeki M., Uchida A., Hirano S., Matsushita N., Kitao H., Oda T., Yamashita T., Kashihara N., Tsubahara A., Takata M., Ishiai M.
    • Journal Title

      Genes Cells 12

      Pages: 299-310

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM.2005

    • Author(s)
      Hirano S.et al.
    • Journal Title

      EMBO J. 24

      Pages: 418-427

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590259
  • [Journal Article] A FancD2-Monoubiquitin Fusion Reveals Hidden Functions of Fanconi Anemia Core Complex in DNA Repair.2005

    • Author(s)
      Matsushita N., Kitao H., Ishiai M., Nagashima N., Hirano S., Okawa K., Ohta T., Yu D.S., McHugh P.J., Hickson I.D., Venkitaraman A.R., Kurumizaka H., Takata M.
    • Journal Title

      Mol. Cell 19

      Pages: 841-847

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM.2005

    • Author(s)
      Hirano S.et al.
    • Journal Title

      EMBO J. 24

      Pages: 418-427

    • Data Source
      KAKENHI-PROJECT-12213059
  • [Journal Article] Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM.2005

    • Author(s)
      Hirano S. et al.
    • Journal Title

      EMBO J. 24

      Pages: 418-427

    • Data Source
      KAKENHI-PROJECT-15590259
  • [Journal Article] Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM.2005

    • Author(s)
      Hirano S.et al.
    • Journal Title

      EMBO J. 26;24(2)

      Pages: 418-427

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12213059
  • [Journal Article] Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM.2004

    • Author(s)
      Hirano S. et al.
    • Journal Title

      EMBO J. 2005 Jan 26 24(2)

      Pages: 418-27

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213059
  • [Presentation] Six2-GDNF Pathway Is Activated during Experimental Acute Kidney Injury and Plays a Crucial Role in Renal Tubular Regeneration2011

    • Author(s)
      平野世紀
    • Organizer
      American Society of Nephrology Kidney Week 2011
    • Place of Presentation
      Philadelphia, USA, ペンシルベニアコンベンションセンター
    • Data Source
      KAKENHI-PROJECT-23591194
  • [Presentation] Six2-GDNF Pathway Is Activated during Experimental Acute Kidney Injury and Plays a Crucial Role in Renal Tubular Regeneration2011

    • Author(s)
      Seiki Hirano, et al.
    • Organizer
      American Society of Nephrology Kidney Week2011
    • Place of Presentation
      ペンシルベニアコンベンションセンター、フィラデルフィア,USA
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-23591194
  • 1.  MATSUSHITA Nobuko (30333222)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 2.  TAKATA Minoru (30281728)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 3.  KITAO Hiroyuki (30368617)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 4.  TERADA Yoshio (30251531)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  KIURA Katsuyuki (10243502)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  ISHII Masamichi (90298844)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  冨田 純也 (50511367)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  山本 和彦 (40333223)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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