KAMIGAKI TAKASHI 神垣隆

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KAMIGAKI Takashi 神垣隆

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Researcher Number	20372641
Other IDs
Affiliation (Current)	2025: 順天堂大学, 健康総合科学先端研究機構, 特任教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 順天堂大学, 健康総合科学先端研究機構, 特任教授 2019 – 2020: 順天堂大学, 医学(系)研究科(研究院), 特任教授 2018: 神戸大学, 医学研究科, 客員教授 2017: 神戸大学, 医学部附属病院, 講師 2016: 神戸大学, 医学研究科, 客員教授 … More 2015: 神戸大学, 医学(系)研究科(研究院), 客員教授 2015: 神戸大学, 大学院医学研究科, 客員教授 2013: 神戸大学, 医学(系)研究科(研究院), 教授 2012: 神戸大学, 医学(系)研究科(研究院), 客員教授 2010 – 2012: 神戸大学, 医学研究科, 客員教授 2006 – 2008: 神戸大学, 医学部附属病院, 講師 2004 – 2006: 神戸大学, 医学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related / Basic Section 90130:Medical systems-related / Basic Section 90140:Medical technology assessment-related / Basic Section 55020:Digestive surgery-related / Digestive surgery Except Principal Investigator Digestive surgery
Keywords	Principal Investigator CTL / MHC / 特異的傷害性T 細胞 / 膠芽腫 / ネオアンチゲン / 複合的免疫療法 / Cold Tumor / エフェクター細胞 / がん免疫療法 / 2-DG … More / 腫瘍特異抗原 / 免疫糖代謝 / Tリンパ球 / 免疫チェックポイント / 解糖系阻害薬 / PD-1 / tumor immunoloey / TC fusion hybrids / DC / cancer vaccine / VK / dendritic cell / colorectal cancer / pentamer / Pentamer / gp70 env MuLV / CT26大腸癌細胞 / 肺転移 / CT26大腸癌細胞株 / 細胞傷害性Tリンパ球 / 制御性Tリンパ球 / 腫瘍予防モデル / 抗CD25抗体 / 腫瘍細胞・樹状細胞融合 / アロ樹状細胞 / PanO2大腸癌細胞株 / 腫瘍免疫 / 癌細胞・樹状細胞アロ融合 / 癌ワクチン / NK / 樹状細胞 / 大腸癌 … More Except Principal Investigator 大腸癌 / T細胞 / NKT細胞 / 腫瘍免疫 / 同種異系 / メモリーCD8+T細胞 / ゼノグラフト / 樹状細胞 / メモリーCD8+Ｔ細胞 / 同種畏系 / ネオ抗原 / 同種異型反応 / 免疫細胞療法 / 養子免疫 / ペプチドプール / 補助療法 / 食道癌 / CD4+T細胞 / 小腸大腸肛門外科学 / 動物 / 薬剤反応性 / 癌 / 集学的治療 / 化学療法 / 粒子線療法 / 膵癌 Less

Immunological evaluation and POC establishment in neoantigen-specific combined immunotherapy for cold tumorPrincipal Investigator
- Principal Investigator
  
  神垣隆
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90140:Medical technology assessment-related
  Basic Section 90130:Medical systems-related
  Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related
- Research Institution
  Juntendo University
Development of comprehensive cancer immunotherapy using PD-1 positive tumor specific T lymphocytesPrincipal Investigator
- Principal Investigator
  
  KAMIGAKI Takashi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Juntendo University
Elucidation of the mechanism of immune activation and identification of novel target molecules associated with allogeneic reactions
- Principal Investigator
  
  Yamashita Kimihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kobe University
Establishment of postoperative adjuvant immunotherapy using peptide pool of tumor antigens in advanced esophageal cancer
- Principal Investigator
  
  Nakamura Tetsu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kobe University
Development of cancer treatment harnessing NKT cells with a cross-talk of innate and acquired immunity
- Principal Investigator
  
  Yamashita Kimihiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kobe University
Efficient induction and maintenance in vivo of tumor antigen specificCD4+ T cells in cancer immunotherapy
- Principal Investigator
  
  YAMASHITA Kimihiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kobe University
Selection of long survivor with biliary tract cancer treated with gemcitabine
- Principal Investigator
  
  AJIKI Tetsuo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kobe University
進行膵癌に対する術前抗癌剤粒子線併用療法の確立に向けての基礎的研究
- Principal Investigator
  
  KURODA Yoshikazu
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kobe University
Development of allogeneic dendriticcell /tumor cell fusion hybrids vaccine based on MHC classI restrictionPrincipal Investigator
- Principal Investigator
  
  KAMIGAKI Takashi
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kobe University

All 2020 2019 2018 2016 2013 2012 2011 2008 Other

All Journal Article Presentation

[Journal Article] Prognostic Factors for Endometrial and Cervical Cancers of Uterus Treated With Immune-cell Therapy: A Retrospective Study2020
- Author(s)
  Takimoto R, Kamigaki T, Okada S, Ibe H, Oguma E, Naitoh K, Makita K, Yasumoto K, Goto S.
- Journal Title
  
  Anticancer Res
  
  Volume: 40(8) Issue: 8 Pages: 4729-4740
- DOI
  10.21873/anticanres.14474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09158
[Journal Article] Identification of prognostic factors for γδT cell immunotherapy in patients with solid tumor2020
- Author(s)
  Takimoto R, Miyashita T, Mizukoshi E, Kamigaki T, Okada S, Ibe H, Oguma E, Naitoh K, Yasumoto K, Makita K, Tomita K, Goto S.
- Journal Title
  
  Cytotherapy
  
  Volume: 22(6) Issue: 6 Pages: 329-336
- DOI
  10.1016/j.jcyt.2020.02.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09158
[Journal Article] Effects of adaptive immune cell therapy on the immune cell profile in patients with advanced gastric cancer2020
- Author(s)
  Miura Miyabi、Mizukoshi Eishiro、Hashiba Tomomi、Kitahara Masaaki、Miyashita Tomoharu、Mochizuki Takafumi、Goto Shigenori、Kamigaki Takashi、Takimoto Rishu、Yamashita Taro、Sakai Yoshio、Yamashita Tatsuya、Honda Masao、Kaneko Shuichi
- Journal Title
  
  Cancer Medicine
  
  Volume: 9 Issue: 14 Pages: 4907-4917
- DOI
  10.1002/cam4.3152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-19K09158
[Journal Article] Prognostic Factors for Colorectal Cancer Patients Treated With Combination of Immune-cell Therapy and First-line Chemotherapy: A Retrospective Study2019
- Author(s)
  TAKIMOTO RISHU、KAMIGAKI TAKASHI、OKADA SACHIKO、MATSUDA ERIKO、IBE HIROSHI、OGUMA ERI、NAITOH KEIKO、MAKITA KAORI、GOTO SHIGENORI
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Issue: 8 Pages: 4525-4532
- DOI
  10.21873/anticanres.13629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09158
[Journal Article] Host CD40 Is Essential for DCG Treatment Against Metastatic Lung Cancer.2016
- Author(s)
  Yamashita K, Hasegawa H, Fujita M, Nishi M, Tanaka T, Arimoto A, Suzuki S, Kamigaki T, Kakeji Y
- Journal Title
  
  Anticancer Res.
  
  Volume: 36 Pages: 3659-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10100
[Journal Article] Host CD40 Is Essential for DCG Treatment Against Metastatic Lung Cancer.2016
- Author(s)
  Yamashita K, Hasegawa H, Fujita M, Nishi M, Tanaka T, Arimoto A, Suzuki S, Kamigaki T, Kakeji Y
- Journal Title
  
  Anticancer Res.
  
  Volume: 36 Pages: 3659-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10541
[Journal Article] Immunotherapy of autologous tumor lysate-loaded dendritic cell vaccines by a closed-flow electroporation system for solid tumors.2013
- Author(s)
  Kamigaki T, Kaneko T, Naitoh K, Takahara M, Kondo T, Ibe H, Matsuda E, Maekawa R, Goto S.
- Journal Title
  
  Anticancer Res.
  
  Volume: 33(7) Pages: 2971-2976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462056
[Journal Article] Extended survival observed in adoptive activated T lymphocyte immunotherapy for advanced lung cancer:results of a multicenter historical cohort study2012
- Author(s)
  Iwai K、Soejima K、Kudoh S、Umezato Y、Kaneko T 、 Yoshimori K 、 Tokuda H 、Yamaguchi T、Mizono A、Setoguchi Y、Kamigaki T、Fujimoto K、Goto S
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: 61巻 10号 Pages: 1781-1790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591487
[Journal Article] Extended survival observed in adoptive activated T lymphocyte immunotherapy for advanced lung cancer: results of a multicenter historical cohort study.2012
- Author(s)
  Iwai K,Soejima K, Kudoh S, Umezato Y, Kaneko T, Yoshimori K, Tokuda H, Yamaguchi T, Mizoo A, Setoguchi Y, Kamigaki T, Fujimoto K, Goto S
- Journal Title
  
  Cancer Immunol Immunother.
  
  Volume: 61巻10号 Pages: 1781-1790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591487
[Journal Article] Rab27a negatively regulates phagocytosis by prolongation of the actin-coating stage around phagosomes2011
- Author(s)
  Yokoyama K, Kaji H, He J, Tanaka C, Hazama R, Kamigaki T, Ku Y, Tohyama K, Tohyama Y
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 5374-5382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591487
[Journal Article] Rab27a negatively regulates phagocytosis by prolongation of the actin-coating stage around phagosomes2011
- Author(s)
  Yokoyama K、Kaji H、He J、Tanaka C、 Hazama R、Kamigaki T、Ku Y、Tohyama K、 Tohyama Y
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 286巻 Issue: 7 Pages: 5375-5382
- DOI
  10.1074/jbc.m110.171702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591487
[Journal Article] Rab27a Negatively Regulates Phagocytosis by Prolongation of the Actin-coating Stage around Phagosomes.2011
- Author(s)
  Kamigaki T, (9名中6番目)
- Journal Title
  
  J Biol Chem.
  
  Volume: 7巻 Pages: 5375-5382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591487
[Journal Article] Enhancement of anti-tumor immunity by high levels of Th1 and Thl7 with a combination of dendritic cell fusion hybrids and regulatory Tcell depletion in pancreatic cancer
- Author(s)
  Kamigaki T, Kuroda Y
- Journal Title
  
  Oncol Rep (in press)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659383
[Presentation] 子宮癌に対する免疫細胞療法の予後規定因子に関する検討2020
- Author(s)
  瀧本理修、神垣隆、岡田佐知子、井邊寛、小熊恵利、内藤恵子、牧田香理、安元公正、後藤重則
- Organizer
  第17回日本免疫治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09158
[Presentation] 子宮癌に対する免疫細胞療法の予後規定因子に関する検討2020
- Author(s)
  瀧本理修、神垣隆、岡田佐知子、他
- Organizer
  第17回日本免疫治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09158
[Presentation] Electroporation as a feasible method for antigen delivering into vectors loaded with NKT cell ligand.2018
- Author(s)
  Arimoto A,Nishi M,Yamashita K,Sugita Y,Fukuoka E,Tanaka T,Kamigaki T ,Takimoto R,Kakeji Y
- Organizer
  AACR Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10541
[Presentation] The anti-tumor efficacy by regulatory T cells depletion in addition to DC vaccines for murine pancreatic cancer2008
- Author(s)
  Yamamoto M, Kamigaki T, Iwatani Y, Nakamura T, et al.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-18659383

1. YAMASHITA Kimihiro (80535427)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. NAKAMURA Tetsu (10403247)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. KURODA Yoshikazu (70178143)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. KAKEJI Yoshihiro (80284488)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. AJIKI Tetsuo (80379403)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 瀧本理修 (10336399)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. 近藤聡英 (70338359)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. FUJITA Tsunenori (00314477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. GU Eisei (40195615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUMI Yasuo (00529521)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKASE Shiro (00379405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. IWATANI Yoshiteru (00457079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. AOI Takashi (00546997)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 菱川良夫 (20122335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 村上昌雄 (50210018)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 藤野泰宏 (30335450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 栄田敏之 (00304098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 川崎健太郎 (90379404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 岡田誠治 (50282455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 藤田貢 (40609997)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 杉本起一 (30407275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 二見淳一郎 (00420498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. TANAKA Tomoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. NISHI Masayasu

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 本多政夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAMIGAKI TAKASHI 神垣 隆

KAMIGAKI Takashi 神垣 隆

Research Projects

Research Products

Co-Researchers

Immunological evaluation and POC establishment in neoantigen-specific combined immunotherapy for cold tumorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of comprehensive cancer immunotherapy using PD-1 positive tumor specific T lymphocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of immune activation and identification of novel target molecules associated with allogeneic reactions

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of postoperative adjuvant immunotherapy using peptide pool of tumor antigens in advanced esophageal cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of cancer treatment harnessing NKT cells with a cross-talk of innate and acquired immunity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Efficient induction and maintenance in vivo of tumor antigen specificCD4+ T cells in cancer immunotherapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Selection of long survivor with biliary tract cancer treated with gemcitabine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

進行膵癌に対する術前抗癌剤粒子線併用療法の確立に向けての基礎的研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of allogeneic dendriticcell /tumor cell fusion hybrids vaccine based on MHC classI restrictionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Prognostic Factors for Endometrial and Cervical Cancers of Uterus Treated With Immune-cell Therapy: A Retrospective Study2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of prognostic factors for γδT cell immunotherapy in patients with solid tumor2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of adaptive immune cell therapy on the immune cell profile in patients with advanced gastric cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic Factors for Colorectal Cancer Patients Treated With Combination of Immune-cell Therapy and First-line Chemotherapy: A Retrospective Study2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Host CD40 Is Essential for DCG Treatment Against Metastatic Lung Cancer.2016

KAMIGAKI TAKASHI 神垣隆

KAMIGAKI Takashi 神垣隆