ono yasuko 小野弥子

… Alternative Names

ONO Yasuko 小野弥子

小野弥子オノヤスコ

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Researcher Number	20392376
Other IDs
Affiliation (Current)	2024: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 副参事研究員
Affiliation (based on the past Project Information) *help	2021 – 2024: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 副参事研究員 2020: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, プロジェクトリーダー 2018 – 2019: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 副参事研究員 2017: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 副参事研究員 2016: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 副参事研究員 … More 2013 – 2015: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主席研究員 2014: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 主席研究員 2011: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主席研究員 2010: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 2010: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主席研究員 2008: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 2007: 東京都臨床医学総合研究所, 主任研究員 2007: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 主任研究員 2005 – 2006: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 Less
Review Section/Research Field	Principal Investigator Functional biochemistry / Basic Section 43030:Functional biochemistry-related / Basic Section 44010:Cell biology-related Except Principal Investigator Functional biochemistry / Biological Sciences / Basic Section 59040:Nutrition science and health science-related / Pathological medical chemistry / Neurophysiology and muscle physiology
Keywords	Principal Investigator カルパイン / プロテアーゼ / 骨格筋 / 筋ジストロフィー / サルコメア / プロテオーム解析 / タンパク質分解 / 機能制御 / ストレス応答 / CBSWドメイン … More / ほ乳類 / タンパク質間相互作用 / ドメイン構造 / プロテアーゼ複合体 / ノックイン / ドメイン / 相互作用タンパク質 / 致死 / ノックアウト / マウス / タンパク質代謝 / ノックアウトマウス / 進化的保存性 / 細胞内局在 / 相互作用検出 / 致死性 / タンパク質相互作用 / プロテオーム / ノックインマウス / 自己消化活性 / 分解断片の定量 / MS / LC-MS / タンパク質発現系 / 骨格筋のストレス応答系 / MARP(筋アンキリンリピートタンパク質 / 活性制御 / mdmマウス / タイチン / コネクチン / カルパイン3 / p94 … More Except Principal Investigator カルパイン / 骨格筋 / プロテオリシス / 筋ジストロフィー / 酵素 / メンブレン・トラフィック / 蛋白質 / 胃腸 / カルシウム / 細胞内タンパク質分解 / シグナル伝達 / ユビキチンリガーゼ / ノックインマウス / モジュレータ・プロテアーゼ / 死細胞クリアランス / 肥満 / マクロファージ / mRNAスプライシング / ノックアウトマウス / 肢帯型筋ジストロフィー2A / プロテオーム解析 / プロテオミクス / カルパイン３ / 肢帯型筋ジストロフィー / 骨格筋の分化成熟 / 筋線維型 / カルパイン3 / 筋成熟遅滞 / カルパイン-3 / 肢帯型筋ジストロフィー2A型 / プロテアーゼ / 遺伝子改変マウス / 組織特異的発現 / 基質特異性 / 酵素学 / 自己消化 / 胃腸疾患 / 質量分析 / 内膜輸送系 / コネクチン / タンパク質 Less

筋特異的カルパインの構造と局在変化による多機能性の解明Principal Investigator
- Principal Investigator
  
  小野弥子
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Homeostatic regulation of metabolic organs by splicing factors and its clinical application
- Principal Investigator
  
  宮崎拓郎
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Showa University
Characterization of structure dependent CAPN7 activityPrincipal Investigator
- Principal Investigator
  
  ONO Yasuko
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Elucidation of molecular mechanism of limb-girdle muscular dystrophy through comparative analysis of calpain-3 mutant mice
- Principal Investigator
  
  SHINKAI-OUCHI Fumiko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
The role of CAPN7 in the adaptation to environmental changePrincipal Investigator
- Principal Investigator
  
  ONO Yasuko
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Tissue-specific functional studies on calpains
- Principal Investigator
  
  SORIMACHI Hiroyuki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Developing sensor-proteins to detect CAPN3 protease activity
- Principal Investigator
  
  OJIMA Koichi
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  National Agriculture and Food Research Organization
Functional aspect of skeletal muscle-specific calpain systemPrincipal Investigator
- Principal Investigator
  
  ONO Yasuko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  公益財団法人東京都医学総合研究所
   Tokyo Metropolitan Organization for Medical Research
Novel functions of evolutionarily conserved calpain-7/PalBH in membrane trafficking system.
- Principal Investigator
  
  SORIMACHI Hiroyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Biomodulation by calpain
- Principal Investigator
  
  SORIMACHI Hiroyuki
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  財団法人東京都医学研究機構
   Tokyo Metropolitan Organization for Medical Research
骨格筋におけるカルパインシステムの役割と制御機構の解析Principal Investigator
- Principal Investigator
  
  小野弥子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
カルパインによる筋細胞監視システムとその破綻による筋ジストロフィー
- Principal Investigator
  
  SORIMACHI Hiroyuki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

[Book] In "Encyclopedia of Biological Chemistry 2^<nd> Edition2013
- Author(s)
  Sorimachi, H., Hata, S., and Ono, Y. Calpain
- Total Pages
  3232
- Publisher
  Elsevier, Oxford; eds., M.D. Lane and W. J. Lennarz
- Data Source
  KAKENHI-PROJECT-22770139
[Book] Chapter 471: μ-calpain, Chapter 472: m-calpain, Chapter 473: Muscle calpain, Chapter 474: Gastrointestinal calpain, Chapter 476: Other calpains. in: Handbook of Proteolytic enzymes, 3rd Edition. N.D. RawlIngs, G. Salvesen, editors2013
- Author(s)
  Sorimachi, H., Hata, S., Ono, Y
- Total Pages
  3932
- Publisher
  Elsevier Academic Press (Oxford)
- Data Source
  KAKENHI-PROJECT-22770139
[Book] 「カルパイン」,モデル動物利用マニュアル…<生物機能モデルと新しいリソース・リサーチツール>2011
- Author(s)
  反町洋之,秦勝志,小野弥子
- Total Pages
  671
- Publisher
  株式会社LIC
- Data Source
  KAKENHI-PROJECT-22770139
[Book] 骨格筋特異的カルパイン-3の活性制御因子は細胞内Na+～例外か多様性か（化学と生物 49-4））2011
- Author(s)
  小野弥子
- Total Pages
  3
- Publisher
  学会出版センター
- Data Source
  KAKENHI-PROJECT-22770139
[Journal Article] Hypercholesterolemic Dysregulation of Calpain in Lymphatic Endothelial Cells Interferes With Regulatory T-Cell Stability and Trafficking.2022
- Author(s)
  T. Miyazaki, Y. Taketomi, T. Higashi, H. Ohtaki, T. Takaki, K. Ohnishi, M. Hosonuma, N. Kono, R. Akasu, S. Haraguchi, JR. Kim-Kaneyama, K. Otsu, H. Arai, M. Murakami, A. Miyazaki
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 43 Issue: 2
- DOI
  10.1161/atvbaha.122.317781
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07370, KAKENHI-PROJECT-21K08585, KAKENHI-PROJECT-22K09317, KAKENHI-PROJECT-21K19327, KAKENHI-PROJECT-22K19737, KAKENHI-PROJECT-20K17431, KAKENHI-PUBLICLY-21H00228, KAKENHI-PROJECT-23K21623, KAKENHI-PROJECT-23K24777
[Journal Article] Cryptic splicing events result in unexpected protein products from calpain-10 (CAPN10) cDNA2022
- Author(s)
  Ono Yasuko、Doi Naoko、Shindo Mayumi、Panico Pablo、Salazar Ana Maria
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  
  Volume: 1869 Issue: 3 Pages: 119188-119188
- DOI
  10.1016/j.bbamcr.2021.119188
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06236
[Journal Article] Enyzmes | Calpains2021
- Author(s)
  Ono Yasuko、Shinkai-Ouchi Fumiko、Noguchi Aya、Hata Shoji
- Journal Title
  
  Encyclopedia of Biological Chemistry
  
  Volume: 3 Pages: 280-291
- DOI
  10.1016/b978-0-12-819460-7.00330-3
- ISBN
  9780128220405
- Open Access
- Data Source
  KAKENHI-PROJECT-18K06236
[Journal Article] A muscle-specific calpain, CAPN3, forms a homotrimer2020
- Author(s)
  Hata Shoji、Doi Naoko、Shinkai-Ouchi Fumiko、Ono Yasuko
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  
  Volume: 1868 Issue: 7 Pages: 140411-140411
- DOI
  10.1016/j.bbapap.2020.140411
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06236, KAKENHI-PROJECT-20K07044
[Journal Article] Calpain-2 participates in the process of calpain-1 inactivation.2020
- Author(s)
  Shinkai-Ouchi F, Shindo M, Doi N, Hata S, Ono Y
- Journal Title
  
  Bioscience Report
  
  Volume: 40 Issue: 11
- DOI
  10.1042/bsr20200552
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06236, KAKENHI-PROJECT-20K07044
[Journal Article] Developing fluorescence sensor probe to capture activated muscle-specific calpain-3 (CAPN3) in living muscle cells2020
- Author(s)
  Ojima K, Hata S, Shinkai-Ouchi F, Oe M, Muroya S, Sorimachi H, Ono Y
- Journal Title
  
  Biology Open
  
  Volume: 9
- DOI
  10.1242/bio.048975
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06236, KAKENHI-PROJECT-20K07044
[Journal Article] Elucidation of the molecular mechanism of disease development due to calpain dysfunction-CALPAIN.2018
- Author(s)
  Sorimachi H, Ono Y, Hata S, Shimakai-Ouchi F
- Journal Title
  
  Impact
  
  Volume: 2018 Issue: 2 Pages: 74-76
- DOI
  10.21820/23987073.2018.2.74
- Open Access
- Data Source
  KAKENHI-PROJECT-26450172, KAKENHI-PROJECT-26670166
[Journal Article] Predictions of Cleavability of Calpain Proteolysis by Quantitative Structure-Activity Relationship Analysis Using Newly Determined Cleavage Sites and Catalytic Efficiencies of an Oligopeptide Array.2016
- Author(s)
  Shinkai-Ouchi F, Koyama S, Ono Y, Hata S, Ojima K, Shindo M, duVerle D, Ueno M, Kitamura F, Doi N, Takigawa I, Mamitsuka H, Sorimachi H.
- Journal Title
  
  Mol Cell Proteomics
  
  Volume: 15 Issue: 4 Pages: 1262-1280
- DOI
  10.1074/mcp.m115.053413
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25440059, KAKENHI-PROJECT-26450172, KAKENHI-PROJECT-26670166, KAKENHI-PROJECT-15H02389
[Journal Article] Calpain research for drug discovery: challenges and potential.2016
- Author(s)
  Ono Y, Saido TC, Sorimachi H
- Journal Title
  
  Nat Rev Drug Discov
  
  Volume: 15 Issue: 12 Pages: 854-876
- DOI
  10.1038/nrd.2016.212
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H02389, KAKENHI-PROJECT-25440059
[Journal Article] An eccentric calpain, CAPN3/p94/calpain-3.2016
- Author(s)
  Ono, Y., Ojima, K., Shinkai-Ouchi, F., Hata, S., and Sorimachi, H.
- Journal Title
  
  Biochimie
  
  Volume: 122 Pages: 169-87
- DOI
  10.1016/j.biochi.2015.09.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25440059, KAKENHI-PROJECT-26670166, KAKENHI-PROJECT-15H02389, KAKENHI-PROJECT-26450172
[Journal Article] Involvement of calpain-7 in epidermal growth factor receptor degradation via the endosomal sorting pathway2014
- Author(s)
  Yuki Maemoto, Yasuko Ono, Satomi Kiso, Hideki Shibata, Terunao Takahara, Hiroyuki Sorimachi, Masatoshi Maki
- Journal Title
  
  The FEBS Journal
  
  Volume: 281 Issue: 16 Pages: 3642-3655
- DOI
  10.1111/febs.12886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580138, KAKENHI-PROJECT-25440059
[Journal Article] Muscle-specific calpain-3 is phosphorylated in its unique insertion region for enrichment in a myofibril fraction2014
- Author(s)
  Ojima, K. Ono, Y. Hata, S. Noguchi, S. Nishino, I. Sorimachi, H.
- Journal Title
  
  Genes to Cells
  
  Volume: 19 Issue: 11 Pages: 830-841
- DOI
  10.1111/gtc.12181
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23500477, KAKENHI-PROJECT-26450172
[Journal Article] The N- and C-terminal autolytic fragments of CAPN3/p94/calpain-3 restore proteolytic activity by intermolecular complementation.2014
- Author(s)
  Ono, Y., Shindo, M., Doi, N., Kitamura, F., Gregorio, C. C., and Sorimachi, H.
- Journal Title
  
  Proc. Natl. Acad. Sci. U. S. A.
  
  Volume: 111 Issue: 51
- DOI
  10.1073/pnas.1411959111
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23247021
[Journal Article] PLEIAD/SIMC1/C5orf25, a Novel Autolysis Regulator for a Skeletal-Muscle-Specific Calpain, CAPN3, Scaffolds a CAPN3 Substrate, CTBP12013
- Author(s)
  Ono, Y., Iemura, SI., Novak, S. M., Doi, N., Kitamura, F., Natsume, T., Gregorio, C. C., Sorimachi H
- Journal Title
  
  J. Mol. Biol
  
  Volume: (in press) Issue: 16 Pages: 2955-2972
- DOI
  10.1016/j.jmb.2013.05.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770139, KAKENHI-PLANNED-24115007
[Journal Article] Calpain-6 deficiency promotes skeletal muscle development and regeneration.2013
- Author(s)
  Tonami, K., Hata, S., Ojima, K., Ono, Y., Kurihara, Y., Amano, T., Sato, T., Kawamura, Y., Kurihara, H., Sorimachi, H.
- Journal Title
  
  PLOS Genetics
  
  Volume: 9 Issue: 8 Pages: 1003668-1003668
- DOI
  10.1371/journal.pgen.1003668
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11J02638, KAKENHI-PROJECT-23247021, KAKENHI-PROJECT-23590326, KAKENHI-PROJECT-23780152, KAKENHI-PUBLICLY-24115705, KAKENHI-PROJECT-24249047
[Journal Article] Understanding the substrate specificity of conventional calpains2012
- Author(s)
  Sorimachi, H., Mamitsuka, H., Ono, Y
- Journal Title
  
  Biol. Chem
  
  Volume: 393 Issue: 9 Pages: 853-871
- DOI
  10.1515/hsz-2012-0143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
[Journal Article] Calpains - An elaborate proteolytic system2012
- Author(s)
  Ono Y, Sorimachi H
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1824 Issue: 1 Pages: 224-236
- DOI
  10.1016/j.bbapap.2011.08.005
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
[Journal Article] Regulation and physiological roles of the calpain system in muscular disorders2012
- Author(s)
  Sorimachi, H., Ono, Y
- Journal Title
  
  Cardiovasc. Res
  
  Volume: 96 Issue: 1 Pages: 11-22
- DOI
  10.1093/cvr/cvs157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
[Journal Article] Chapter 453-6 and 458. μ-calpain, m-calpain, Muscle calpain, Gastrointestinal calpain, and other calpains.2012
- Author(s)
  Sorimachi H, Ono Y, Hata S
- Journal Title
  
  Handbook of Proteolytic enzymes, 3rd Edition(Rawlings ND, Salvesen G, eds)(Oxford, UK: Elsevier Academic Press.)
  
  Volume: in press
- URL
  http://store.elsevier.com/product.jsp?Isbn=9780123822192&pagename=search
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Does the severity of the LGMD2A phenotype in compound heterozygotes depend on the combination of mutations?2011
- Author(s)
  Saenz A., Ono Y., Sorimachi H., Goicoechea M., Leturcq F., Blazquez L., Garcia-Bragado F., Marina A., Poza J.J., Azpitarte M., Doi N., Urtasun M., Kaplan J.C., Lopez de Munain A.
- Journal Title
  
  Muscle Nerve (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] 肢帯型筋ジストロフィーの発症機構2011
- Author(s)
  反町洋之、小野弥子
- Journal Title
  
  生体の科学 62(in press)
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] Calpain cleavage prediction using multiple kernel learning.2011
- Author(s)
  duVerle D. A., Ono Y., Sorimachi H., Mamitsuka H.
- Journal Title
  
  PLoS One (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] Calpain cleavage prediction using multiple kernel learning.2011
- Author(s)
  duVerle DA, Ono Y, Sorimachi H, Mamitsuka H
- Journal Title
  
  PLoS One
  
  Volume: 6 Issue: 5 Pages: e19035-e19035
- DOI
  10.1371/journal.pone.0019035
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139
[Journal Article] 肢帯型筋ジストロフィーの発症機構2011
- Author(s)
  反町洋之,小野弥子
- Journal Title
  
  生体の科学
  
  Volume: 62-2 Pages: 95-99
- Data Source
  KAKENHI-PROJECT-22770139
[Journal Article] Calpain chronicle-an enzyme family under multidisciplinary characterization2011
- Author(s)
  Sorimachi, H., Hata, S., Ono, Y
- Journal Title
  
  Proc Jpn Acad Ser B Phys Biol Sci
  
  Volume: 87 Pages: 287-327
- NAID
  130000903736
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153876/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770139
[Journal Article] Calpain chronicle-an enzyme family under multidisciplinary characterization.2011
- Author(s)
  反町洋之, 秦勝志, 小野弥子
- Journal Title
  
  Proc.Jpn.Acad.Ser.B 87(in press)
- NAID
  130000903736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] カルパインの組織機能論2011
- Author(s)
  反町洋之,秦勝志,小野弥子
- Journal Title
  
  実験医学
  
  Volume: 29 Pages: 1882-1890
- Data Source
  KAKENHI-PROJECT-22770139
[Journal Article] Does the severity of the LGMD2A phenotype in compound heterozygotes depend on the combination of mutations?2011
- Author(s)
  Saenz A, Ono Y, Sorimachi H, Goicoechea M, Leturcq F, Blazquez L, Garcia-Bragado F, Marina A, Poza JJ, Azpitarte M, Doi N, Urtasun M, Kaplan JC, Lopez de Munain A
- Journal Title
  
  Muscle and Nerve
  
  Volume: 44 Issue: 5 Pages: 710-714
- DOI
  10.1002/mus.22194
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
[Journal Article] 骨格筋特異的カルパイン-3の活性制御因子は細胞内Na^+～例外か多様性か2011
- Author(s)
  小野弥子,反町洋之
- Journal Title
  
  化学と生物 49
  
  Pages: 229-231
- NAID
  10028117186
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] Calpain chronicle--an enzyme family under multidisciplinary characterization.2011
- Author(s)
  Sorimachi H, HataS, Ono Y
- Journal Title
  
  Proc Jpn Acad Ser B Phys Biol Sci
  
  Volume: 87 Pages: 287-327
- NAID
  130000903736
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Impact of genetic insights into calpain biology2011
- Author(s)
  Sorimachi H, Hata S, Ono Y
- Journal Title
  
  J Biochem
  
  Volume: 150 Issue: 1 Pages: 23-37
- DOI
  10.1093/jb/mvr070
- NAID
  10030586192
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139
[Journal Article] Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles.2011
- Author(s)
  Ojima K., Ono Y., Ottenheijm C., Hata S., Suzuki H., Granzier H., Sorimachi H.
- Journal Title
  
  J.Mol.Biol. 407
  
  Pages: 439-449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles.2011
- Author(s)
  Ojima K, Ono Y, Ottenheijm C, HataS, Suzuki H, Granzier H, Sorimachi H
- Journal Title
  
  J Mol Biol
  
  Volume: 407 Issue: 3 Pages: 439-449
- DOI
  10.1016/j.jmb.2011.01.057
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
[Journal Article] カルパインの組織機能論2011
- Author(s)
  反町洋之、秦勝志、小野弥子
- Journal Title
  
  実験医学 29(in press)
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] 骨格筋特異的カルパイン-3の活性制御因子は細胞内Na^+～例外か多様性か2011
- Author(s)
  小野弥子,反町洋之
- Journal Title
  
  化学と生物
  
  Volume: 49-4 Pages: 229-231
- NAID
  10028117186
- Data Source
  KAKENHI-PROJECT-22770139
[Journal Article] Skeletal muscle-specific calpain is an intracellular Na+-dependent protease.2010
- Author(s)
  Ono Y., Ojima K., Torii F., Takaya E., Doi N., Nakagawa K., Hata S., Abe K., Sorimachi H.
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 22986-22998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy.2010
- Author(s)
  Ojima K, Kawabata Y, Nakao H, Nakao K, Doi N, Kitamura F, Ono Y, HataS, Suzuki H, Kawahara H, Bogomolovas J,Will C, Ottenheijm C, LabeitS, Granzier H, Toyama-Sorimachi N, Sorimachi M, Suzuki K, Maeda T, Abe K, Aiba A, Sorimachi H
- Journal Title
  
  J Clin Invest
  
  Volume: 120 Issue: 8 Pages: 2672-2683
- DOI
  10.1172/jci40658
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22300106, KAKENHI-PROJECT-22770139
[Journal Article] Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy2010
- Author(s)
  Ojima, K., Kawabata, Y., Nakao, H., Nakao, K., Doi, N., Kitamura, F., Ono, Y., Hata, S., Suzuki, H., Kawahara, H., Bogomolovas, J., Witt, C., Ottenheijm, C., Labeit, S., Granzier, H., Toyama-Sorimachi, N., Sorimachi, M., Suzuki, K., Maeda, T., Abe, K., Aiba, A., Sorimachi, H.
- Journal Title
  
  J.Clin.Invest.
  
  Volume: 120 Pages: 2672-2683
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Redundant and non-redundant effects of Ca^<2+> and Na^+ on the activation of p94/calpain-3.2010
- Author(s)
  Ono, Y.
- Journal Title
  
  Neuromuscul. Disord.
  
  Volume: 20 Pages: 608-608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] Expanding members and roles of the calpain superfamily and their genetically modified animals.2010
- Author(s)
  Sorimachi H, Hata S, Ono Y
- Journal Title
  
  Exp Anim
  
  Volume: 59 Pages: 549-566
- NAID
  130000419250
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21030783
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Skeletal muscle-specific calpain is an intracellular Na^+-dependent protease.2010
- Author(s)
  Ono Y, Ojima K, Torii F, Takaya E, Doi N, Nakagawa K, Hata S, Abe K, Sorimachi H
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Issue: 30 Pages: 22986-22998
- DOI
  10.1074/jbc.m110.126946
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139
[Journal Article] CaMPDB: a resource for calpain and modulatory proteolysis.2010
- Author(s)
  duVerle DA, Takigawa I, Ono Y, Sorimachi H, Mamitsuka H
- Journal Title
  
  Genome Inform
  
  Volume: 22 Pages: 202-213
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Skeletal muscle-specific calpain is an intracellular Na^+-dependent protease2010
- Author(s)
  Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 22986-22998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770139
[Journal Article] Expanding members and roles of the calpain superfamily and their genetically modified animals.2010
- Author(s)
  反町洋之, 秦勝志, 小野弥子
- Journal Title
  
  Exp.Anim. 59
  
  Pages: 549-566
- NAID
  130000419250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] Skeletal muscle-specific calpain is an intracellular Na^+-dependent protease2010
- Author(s)
  Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 22986-22998
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Skeletal muscle-specific calpain, p94/calpain-3, dynamically distributes in skeletal muscle cells to adapt to physical stress, defects of which cause muscular dystrophy.2010
- Author(s)
  Ojima K, Ono Y, Doi N, Kitamura F, Kawabata Y, Suzuki K, Maeda T, Abe K, Nakao H, Aiba A, Suzuki H, Kawahara H, Witt C,Ottenheijm C, Labeit S, Ottenheijm C, Granzier H, Toyama-Sorimachi N, Sorimachi M, Sorimachi H
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 20 Pages: 598-599
- URL
  http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Redundant and non-redundant effects of Ca^<2+> and Na^+ on the activation of p94/calpain-3.2010
- Author(s)
  Ono, Y.
- Journal Title
  
  Neuromuscul.Disord.
  
  Volume: 20 Pages: 608-608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] Redundant and non-redundant effects of Ca^<2+> and Na^+ on the activation of p94/calpain-32010
- Author(s)
  Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H.
- Journal Title
  
  Neuromuscul.Disord.
  
  Volume: 20 Pages: 608-608
- Data Source
  KAKENHI-PROJECT-22770139
[Journal Article] Expanding members and roles of the calpain superfamily and their genetically modified animals2010
- Author(s)
  Sorimachi, H., Hata, S., and Ono, Y
- Journal Title
  
  Exp. Anim
  
  Volume: 59 Pages: 549-566
- NAID
  130000419250
- URL
  https://www.jstage.jst.go.jp/article/expanim/59/5/59_5_549/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770139
[Journal Article] Redundant and non-redundant effects of Ca^<2+> and Na^+ on the activation of p94/calpain-3.2010
- Author(s)
  Ono Y, Ojima K, Torii F, Takaya E, Doi N, Nakagawa K, Hata S, Abe K, Sorimachi H
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 20 Pages: 608-608
- URL
  http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy.2010
- Author(s)
  Ojima K., Kawabata Y., Nakao H., Nakao K., Doi N., Kitamura F., Ono Y., Hata S., Suzuki H., Kawahara H., Bogomolovas J., Witt C., Ottenheijm C., Labeit S., Granzier H., Toyama-Sorimachi N., Sorimachi M., Suzuki K., Maeda T., Abe K., Aiba A., Sorimachi H.
- Journal Title
  
  J.Clin.Invest. 120
  
  Pages: 2672-2683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] CaMPDB : a Resource for Calpain and Modulatory Proteolysis.2009
- Author(s)
  duVerle D. A., Takigawa I. Ono Y., Sorimachi H., Mamitsuka H.
- Journal Title
  
  Genome Informatics 22
  
  Pages: 202-214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] CaMPDB : a Resource for Calpain and Modulatory Proteolysis.2009
- Author(s)
  duVerle, D.A., Takigawa, I., Ono, Y., Sorimachi, H., Mamitsuka, H.
- Journal Title
  
  Genome Informatics 22
  
  Pages: 202-214
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] The importance of conserved amino acid residues in protease sub-domain IIb and the IS2 region in p94 for constitutive autolysis2008
- Author(s)
  Ono, Y., Hayashi, C., Doi, N., Tagami, M., Sorimachi, H
- Journal Title
  
  FEBS Lett 582
  
  Pages: 691-698
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] カルパインの生理機能とその不全による病態「カルパイノパチー」2008
- Author(s)
  小野弥子,反町洋之
- Journal Title
  
  実験医学 26
  
  Pages: 306-315
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] Muscle RING-finger protein MuRF1 as a connector of muscle energy metabolism and protein synthesis2008
- Author(s)
  Koyama, S., Hata, S., Witt, C. C. , Ono, Y., Lerche, S., Ojima, K., Chiba, T., Doi, N., Kitamura, F., Tanaka, K., Abe, K., Witt, S., Rybin, V., Gasch, A., Franz, T., Labeit, S., Sorimachi, H
- Journal Title
  
  J. Mol. Biol 376
  
  Pages: 1224-1236
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] The importance of conserved amino acid residues in protease sub-domain IIb and the IS2 region in p94 for constitutive autolysis2008
- Author(s)
  Ono, Y., Hayashi, C., Doi, N., Tagami, M., Sorimachi, H.
- Journal Title
  
  FEBS Lett. 582
  
  Pages: 691-698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] The importance of conserved amino acid residues in p94 protease sub-domain IIb and the IS2 refion for constitutive autolysis2008
- Author(s)
  Ono. Y., Hayaslu, C., Doi, N., Tagami, M., and Sorimachi, H.
- Journal Title
  
  FEBS Lett 582
  
  Pages: 691-698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18770124
[Journal Article] Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle.2008
- Author(s)
  Hayashi C., Ono Y., Doi N., Kitamura F., Tagami M., Mineki R., Arai T., Taguchi H., Yanagida M., Hirner S., Labeit D., Labeit S., Sorimachi H.
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 14801-14814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activityin skeletal muscle2008
- Author(s)
  Hayashi, C., Ono, Y., Doi, N., Kitamura, F., Tagami, M., Mineki, R., Arai, T., Taguchi, H., Yanagida, M., Hirner, S., Labeit, D., Labeit, S., Sorimachi, H
- Journal Title
  
  J. Biol. Chem 283
  
  Pages: 14801-14814
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Muscle RING-Finger Protein(MuRFl)as a Connector of Muscle Energy Metabolism and Protein Synthesis2008
- Author(s)
  Koyama, S., Hata, S., Witt, C.C., Ono, Y., Lerche, S., Ojima, K., Chiba, T., Doi, N., Kitamura, F., Tanaka, K., Abe, K., Witt, S., Rybin, V., Gasch, A., Franz, T., Labeit, S., and Sorimachi, H.
- Journal Title
  
  J.Mol.Biol 376
  
  Pages: 1224-1236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18770124
[Journal Article] Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle2008
- Author(s)
  Hayashi, C., Ono, Y., Doi, N., Kitamura, F., Tagami, M., Mineki, R., Arai, T., Taguchi, H., Yanagida, M., Hirner, S., Labeit, D., Labeit, S., Sorimachi, H.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 14801-14814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p74/calpain 3 activity in skeletal muscle.2008
- Author(s)
  Hayashi, C., Ono. Y., Doi, N., Kitamura, E, Tagami, M., Mineki, R., Arai, T., Taguchi, H., Yanagida, M., Hirner, S., Labeit, D., Labeit, S, and Sorimaclu, H
- Journal Title
  
  J.Biol.Chem 283
  
  Pages: 14801-14814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18770124
[Journal Article] The importance of conserved amino acid residues in protease sub-domain Iib and the IS2 region in p94 for constitutive autolysis.2008
- Author(s)
  Ono, Y., Hayashi, C., Doi, N., Tagami, M., and Sorimachi, H.
- Journal Title
  
  FEBS Lett. 582
  
  Pages: 691-698
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis.2008
- Author(s)
  Koyama S, HataS, Witt CC, Ono Y, Lerche S, Ojima K, Chiba T, Doi N, Kitamura F, Tanaka K, Abe K, Witt SH, Rybin V, Gasch A, Franz T, Labeit S, Sorimachi H
- Journal Title
  
  J Mol Biol
  
  Volume: 376 Issue: 5 Pages: 1224-1236
- DOI
  10.1016/j.jmb.2007.11.049
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] The importance of conserved amino acid residues in p94 protease sub-domain IIb and the IS2 region for constitutive autolysis.2008
- Author(s)
  Ono Y, Hayashi C, Doi N, Tagami M, Sorimachi H
- Journal Title
  
  FEBS Lett
  
  Volume: 582 Pages: 691-698
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Muscle RING-finger protein MuRF1 as a connector of muscle energy metabolism and protein synthesis.2008
- Author(s)
  Koyama S., Hata S., Witt C. C., Ono Y., Lerche S., Ojima K., Chiba T., Doi N., Kitamura F., Tanaka K., Abe K., Witt S., Rybin V., Gasch A., Franz T., Labeit S., Sorimachi H.
- Journal Title
  
  J.Mol.Biol. 376
  
  Pages: 1224-1236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p94/caplain 3 activity in skeletal muscle.2008
- Author(s)
  Hayashi, C., Ono, Y., Doi, N., Kitamura, F., Tagami, M., Mineki, R., Arai, T., Taguchi, H., Yanagida, M., Hirner, S., Labeit, D., Labeit, S., and Sorimachi, H.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 14801-14814
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] The importance of conserved amino acid residues in protease sub-domain IIb and the IS2 region in p94 for constitutive autolysis.2008
- Author(s)
  Ono Y., Hayashi C., Doi N., Tagami M., Sorimachi H.
- Journal Title
  
  FEBS Lett. 582
  
  Pages: 691-698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370055
[Journal Article] Multiple molecular interactions implicate the connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle.2008
- Author(s)
  Hayashi C, Ono Y, Doi N, Kitamura F, Tagami M, Mineki R, Arai T, Taguchi H, Yanagida M, Hirner S, Labeit D, Labeit S, Sorimachi H
- Journal Title
  
  J Biol Chem
  
  Volume: 283 Pages: 14801-14
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Comprehensive survey of p94/calpain 3 substrates by comparative proteomics - Possible regulation of protein synthesis by p942007
- Author(s)
  Ono, Y., Hayashi, C., Doi, N., Kitamura, F., Shindo, M., Kudo, K., Tsubata, T., Yanagida, M., Sorimachi, H
- Journal Title
  
  Biotech. J 2
  
  Pages: 565-576
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Myogenic stage, sarcomere length, and protease activity modulate localization of muscle-specific calpain.2007
- Author(s)
  Ojima K, Ono Y, Doi N, Yoshioka K, Kawabata Y, Labeit S, Sorimachi H
- Journal Title
  
  J Biol Chem
  
  Volume: 282 Issue: 19 Pages: 14493-14504
- DOI
  10.1074/jbc.m610806200
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Comprehensive survey of p94/calpain 3 substrates by comparative proteomics -Possible regulation of protein synthesis by p94.2007
- Author(s)
  Ono, Y., Hayashi, C., Doi, N., Kitamura, F., Shindo, M., Kudo, K., Tsubata, T., Yanagida, M., Sorimachi, H.
- Journal Title
  
  Biotech. J. (in press)
- Data Source
  KAKENHI-PROJECT-18770124
[Journal Article] Myogenic stage, sarcomere length and protease activity modulate localization ofmuscle-specific calpain2007
- Author(s)
  Ojima, K., Ono, Y., Doi, N., Yoshioka, K., Kawabata, Y., Labeit, S., Sorimachi, H
- Journal Title
  
  J. Biol. Chem 282
  
  Pages: 14493-14504
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Comprehensive survey of p94/calpain 3 substrates by comparative proteomics--possible regulation of protein synthesis by p94.2007
- Author(s)
  Ono Y, Hayashi C, Doi N, Kitamura F, Shindo M, Kudo K, Tsubata T, Yanagida M, Sorimachi H
- Journal Title
  
  Biotech J
  
  Volume: 2 Issue: 5 Pages: 565-576
- DOI
  10.1002/biot.200700018
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Suppressed disassembly of autolyzing p94/CAPN3 by N2A connectin/titin in a genetic reporter system.2006
- Author(s)
  Ono Y, Torii F, Ojima K, Doi N, Yoshioka K, Kawabata Y, Labeit D, LabeitS, Suzuki K, Abe K, Maeda T, Sorimachi H
- Journal Title
  
  J Biol Chem
  
  Volume: 281 Issue: 27 Pages: 18519-31
- DOI
  10.1074/jbc.m601029200
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] How do defects in proteolytic functions of skeletal muscle-specific calpain, p94/calpain 3, cause calpainopathy/LGMD2A?2006
- Author(s)
  Sorimachi H, Ojima K, Yanagida M, Ogawa H, Hayashi C, Doi N, Ono Y
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 16
- URL
  http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description.
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Effect of N2A connectin/titin on disassembly of p94/CAPN3 caused by auaolysis in IS2.2006
- Author(s)
  Ono Y, Torii F, Ojima K, Doi N, Yoshioka K, Labeit D, Labeit S, Suzuki K, Abe K, Maeda T, Sorimachi H
- Journal Title
  
  FEBS Journal
  
  Volume: 273 Supp1. Issue: s1 Pages: 50-50
- DOI
  10.1111/j.1742-4658.2006.05276.x
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Spatio-temporal expression of muscle-specific calpain, p94/calpain 3, during myogenesis.2006
- Author(s)
  Ojima K, Ono Y, Doi N, Labeit S, Sorimachi H
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 16
- URL
  http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description.
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] N2A connectin/titin suppressed disassembly of p94/CAPN3 caused by autolysis of IS2 but not IS1 in a genetic reporter system.2006
- Author(s)
  Ono, Y.et al.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 18519-18531
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Suppressed disassembly of autolyzing p94/CAPN3 in a genetic reporter system2006
- Author(s)
  Ono, Y., Torii, F., Ojima, K., Doi, N., Yoshioka, K., Kawabata, Y., Labeit, D., Labeit, S., Suzuki,K., Abe, K., Maeda, T., Sorimachi, H
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 18519-18531
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Spatio-temporal expression of muscle-specific calpain, p94/calpain 3, during myogenesis.2006
- Author(s)
  Ojima, K., Ono, Y., Doi, N., Labeit, S., Sorimachi, H.
- Journal Title
  
  Neuromuscul. Disord. 16, suppl
  
  Pages: 56-56
- Data Source
  KAKENHI-PROJECT-18770124
[Journal Article] How do defects in proteolytic functions of skeletal muscle-specific calpain, p94/calpain 3, cause calpainopathy/LGMD2A?2006
- Author(s)
  Sorimachi, H., Ojima, K., Yanagida, M., Ogawa, H., Hayashi, C., Doi, N., Ono, Y.
- Journal Title
  
  Neuromuscul. Disord. 16, suppl.
  
  Pages: 148-148
- Data Source
  KAKENHI-PROJECT-18770124
[Journal Article] Relationships between p94/CAPN3 and N2A connectin/titin in skeletal muscle under the normal and dystrophic conditions.2006
- Author(s)
  Ono Y, Ojima K, Doi N, Hayashi C, Torii F, 40K, Labeit D, Labeit S, Suzuki K, Abe K, Maeda T, Sorimachi H
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 16
- URL
  http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description.
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Relationships between p94/CAPN3 and N2A connectin/titin in skeletal muscle under the normal and dystrophic conditions.2006
- Author(s)
  Ono, Y., Ojima, K., Doi, N., Hayashi, C., Torii, F., Yoshioka, K., Labeit, D., Labeit, S., Suzuki, K., Abe, K., Maeda, T., Sorimachi, H.
- Journal Title
  
  Neuromuscul. Disord. 16, suppl
  
  Pages: 72-72
- Data Source
  KAKENHI-PROJECT-18770124
[Journal Article] Suppressed disassembly of autolyzing p94/CAPN3 in a genetic reporter system.2006
- Author(s)
  Ono, Y., Torii, F., Ojima, K., Doi, N., Yoshioka, K., Kawabata, Y., Labeit, D., Labeit, S., Suzuki, K., Abe, K., Maeda, T., Sorimachi, H.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 15219-15231
- Data Source
  KAKENHI-PROJECT-18770124
[Journal Article] Effect of N2A connectin/titin on disassembly of p94/CAPN3 caused by auaolysis in IS2.2006
- Author(s)
  Ono, Y., Torii, F., Ojima, K., Doi, N., Yoshioka, K., Labeit, D., Labeit, S., Suzuki, K., Abe, K., Maeda, T., Sorimachi, H.
- Journal Title
  
  FEBS J. 273, suppl.
  
  Pages: 50-50
- Data Source
  KAKENHI-PROJECT-18770124
[Journal Article] N2A connectin/titin suppressed disassembly of p94/CAPN3 caused by autolysis of IS2 but not IS1 in a genetic reporter system.2006
- Author(s)
  Ono, Y.et al.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 18519-18531
- Data Source
  KAKENHI-PROJECT-17028055
[Presentation] nexpected protein products from calpain-10 (CAPN10) cDNA.2019
- Author(s)
  Ono, Y.
- Organizer
  FASEB Summer Research Conferences; The Biology of Calpains in Health and Disease Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06236
[Presentation] カルパインの特性を規定する基質特異性の定量的構造活性相関解析2017
- Author(s)
  大内史子、小山傑、進藤真由美、馬見塚拓、瀧川一学、尾嶋孝一、秦勝志、小野弥子、反町洋之
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学（京都府京都市）
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-26670166
[Presentation] カルパイン3の自己分解と活性化について2017
- Author(s)
  1.小野弥子，土井奈穂子，反町洋之
- Organizer
  2017年度日本農芸化学会大会
- Place of Presentation
  京都女子大学（京都府京都市）
- Data Source
  KAKENHI-PROJECT-25440059
[Presentation] カルパイン３欠損型およびプロテアーゼ活性欠失変異型マウスの比較プロテオミクスによる肢帯型筋ジストロフィー2A型発症機序の解析2016
- Author(s)
  大内史子、進藤真由美、伊藤義城、小野弥子、秦勝志、今西美知子、反町洋之
- Organizer
  日本農芸化学会大会
- Place of Presentation
  札幌コンベンションセンター、北海道札幌市
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-26670166
[Presentation] Quantitative structure-acitivity relationship (QSAR) analysis of calpain substrate specificity---Can we predict cleavage by calpain?2016
- Author(s)
  Shinkai-Ouchi F, Koyama S, Shindo M, Mamitsuka H, Ono Y, Sorimachi H.
- Organizer
  FASEB Science Research Conferences, “The biology of Calpains in health and desease”
- Place of Presentation
  米国　モンタナ州　ビッグスカイ
- Year and Date
  2016-07-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670166
[Presentation] カルパインの基質部位の予測、第21回日本病態プロテアーゼ学会2016
- Author(s)
  2大内史子、小山傑、小野弥子、秦勝志、尾嶋孝一、進藤真由美、duVerle D., 土井奈緖子、瀧川一学、馬見塚拓、反町洋之
- Organizer
  第21回日本病態プロテアーゼ学会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-26670166
[Presentation] Proteomic approach for elucidation of calpains’ substrate specificities2016
- Author(s)
  Shinkai-Ouchi F, Koyama S, Shindo M, Hata S, Ono Y, Mamitsuka H, Sorimachi H
- Organizer
  医学研国際シンポジウム
- Place of Presentation
  公益財団法人東京都医学総合研究所　(東京都世田谷区）
- Year and Date
  2016-06-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670166
[Presentation] 肢帯型筋ジストロフィー2A型のモデルとしてのカルパイン３ノックアウトおよびプロテアーゼ活性欠失変異型マウスの比較プロテオーム解析2015
- Author(s)
  大内史子、進藤真由美、伊藤義城、小野弥子、秦勝志、今西美知子、反町洋之
- Organizer
  病態プロテアーゼ学会
- Place of Presentation
  ANAクラウンプラザホテルグランコート名古屋、愛知県名古屋市
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-26670166
[Presentation] カルパインの基質切断部位の特異席解明に向けた網羅的解析2015
- Author(s)
  大内史子、進藤真由美、小野弥子、秦勝志、反町洋之
- Organizer
  日本農芸化学会大会
- Place of Presentation
  岡山大学　岡山市
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-26670166
[Presentation] Calpain functions and muscle homeostasis/dystrophies2014
- Author(s)
  Sorimachi H, Shinkai-Ouchi F, Tonami K, Ojima K, Doi N, Kitamura F, Hata S, Ono Y
- Organizer
  2014 Yonsei BK21plus-Igakuken joint symposium
- Place of Presentation
  延正大学、ソウル、大韓民国
- Year and Date
  2014-06-19
- Data Source
  KAKENHI-PROJECT-26670166
[Presentation] カルパイン３ノックアウトマウス（CAPN3-KO）、プロテアーゼ活性欠失変異型マウス（CAPN3-CSKI）の表現型比較とCAPN3の非酵素的機能2014
- Author(s)
  大内史子、小野弥子、秦勝志、今西美知子、反町洋之
- Organizer
  病態プロテアーゼ学会
- Place of Presentation
  千里ライフサイエンスセンター　大阪府豊中市
- Year and Date
  2014-08-08
- Data Source
  KAKENHI-PROJECT-26670166
[Presentation] Similarity and difference of substrate selectivities between two conventional calpains2014
- Author(s)
  Shinkai-Ouchi F, Shindo M, Hata S, Ono Y, Sorimachi H
- Organizer
  2014 Yosnei BK21plus-CBSM international joint symposium
- Place of Presentation
  安東、大韓民国
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-26670166
[Presentation] Muscle homeostasis modulated by calpains.2014
- Author(s)
  Sorimachi H, Tonami K, Shinkai-Ouchi F, Hata S, Ojima K, Ono Y
- Organizer
  XIVth Symposium on Proteases, Inhibitors and Biological Control.
- Place of Presentation
  Portoroz, Slovenia
- Year and Date
  2014-09-09
- Invited
- Data Source
  KAKENHI-PROJECT-26670166
[Presentation] カルパイン機能不全と疾患 Calpains in health and disease2013
- Author(s)
  反町洋之、秦勝志、礪波一夫、大内史子、小野弥子
- Organizer
  日本薬学会第133回年会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23247021
[Presentation] Identification of phosphorylation sites of muscle-specific calpain-32013
- Author(s)
  Koichi Ojima, Yasuko Ono, Shoji Hata, Oe Mika, Ikuyo Nakajima, Susumu Muroya, Koichi Chikuni, Hiroyuki Sorimachi
- Organizer
  FASEB Science Research Conferences, The Biology of Calpains in Health and Disease
- Place of Presentation
  Saxton River, VT, USA
- Data Source
  KAKENHI-PROJECT-23500477
[Presentation] Effects of phosphorylation of muscle-specific calpain-3 on its proteolytic activity.2013
- Author(s)
  Koichi Ojima, Yasuko Ono, Shoji Hata, Oe Mika, Ikuyo Nakajima, Susumu Muroya, Koichi Chikuni, Hiroyuki Sorimachi
- Organizer
  2013 Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  NewOrleans, LA, USA
- Data Source
  KAKENHI-PROJECT-23500477
[Presentation] カルパイン3のリン酸化が酵素活性に与える影響2013
- Author(s)
  尾嶋孝一, 小野弥子, 秦勝志, 大江美香, 中島郁世, 千国幸一, 室谷進, 反町洋之
- Organizer
  日本畜産学会第117回大会
- Place of Presentation
  新潟市
- Data Source
  KAKENHI-PROJECT-23500477
[Presentation] STRUCTURE-FUNCTION RELATIONSHIP OF Na^+-DEPENDENT ACTIVITY OF MUSCLE-SPECIFIC CALPAIN2012
- Author(s)
  Ono,Y., Takaya, E., Doi, N., Kitamura, F., Sorimachi, H
- Organizer
  SPIBC 2012(第13回プロテアーゼおよびその阻害剤と生体制御に関する国際会議)
- Place of Presentation
  Portoroz, Slovenia
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] 筋特異的カルパインCAPN3/p94活性化機構における分子間相補の解析 (Inter-molecular interaction involved in the activation of CAPN3/p94)2012
- Author(s)
  小野弥子,田尾あすみ,北村ふじ子,反町洋之
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] 骨格筋特異的に発現するカルパイン3はNa+により活性化する2012
- Author(s)
  尾嶋孝一, 小野弥子, 中島郁世, 大江美香, 室谷進 , 反町洋之
- Organizer
  日本畜産学会第115回大会
- Place of Presentation
  名古屋大学（愛知県）
- Data Source
  KAKENHI-PROJECT-23500477
[Presentation] Towards understanding the enigmatic substrate specificity of calpains2012
- Author(s)
  Sorimachi, H., duVerle, D., Hata, S., Tonami, K., Ouchi, F., Ojima, K., Takigawa, I., Mamitsuka, H. and Ono, Y.
- Organizer
  XIIIth Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  Portoroz, Slovenia
- Invited
- Data Source
  KAKENHI-PROJECT-23247021
[Presentation] Characterization of sodium-dependent protease activity of muscle-specific calpain2012
- Author(s)
  Ono,Y., Ouchi, F., Kitamura, F., Sorimachi, H
- Organizer
  CAPN3. EMC2012(第41回ヨーロッパ筋機能研究学会)
- Place of Presentation
  Rhodes, Greek
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] 筋特異的カルパインCAPN3/p94の新奇活性化機構の解析2011
- Author(s)
  小野弥子,田尾あすみ,北村ふじ子,反町洋之
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] Structure-function relationship of Na^+-dependent activity of calpain-3/p942011
- Author(s)
  Ono, Y
- Organizer
  Korea-Japan symposium on protein metabolism
- Place of Presentation
  Seoul National University, Seoul, Korea
- Year and Date
  2011-01-28
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] Structure-function relationship of Na^+-dependent activity of calpain-3/p942011
- Author(s)
  Ono, Y.
- Organizer
  Korea-Japan symposium on protein metabolism
- Place of Presentation
  ソウル大学(韓国)(招待講演)
- Year and Date
  2011-01-28
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] Studies of titin signaling and CAPN3.2011
- Author(s)
  Sorimachi, H., Ojima, K., and Ono, Y.
- Organizer
  LGMD2A Workshop: Coalition to Cure Calpain 3(C3)
- Place of Presentation
  Santa Monica, USA.
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Structure-Function relationship of Na+-dependent activity of calpain-3/p94.2011
- Author(s)
  小野弥子
- Organizer
  The 17th Symposium on Ca2+-Binding Proteins and Ca2+ Function in Health and Disease
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] Autolytic activity of skeletal muscle-specific calpain, CAPN3, diversifies its functions?2011
- Author(s)
  Ono, Y., Doi, N., Kitamura, F., Sorimachi, H
- Organizer
  CMM, MCB, and CBC joint retreat, Biosphere 2
- Place of Presentation
  University of Arizona, Tucson, USA
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] Does the severity of the LGMD2A phenotype in compound heterozygotes depend on the combination of mutations?2011
- Author(s)
  Ono, Y., Saenz, A., Sorimachi, H., Lopez de Munain, A
- Organizer
  The 7th International Proteolysis Society meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] Functional aspects of unique autolytic activity of CAPN32011
- Author(s)
  Ono, Y
- Organizer
  Department of Cellular and Molecular Medicine
- Place of Presentation
  University of Arizona, Tucson, USA
- Year and Date
  2011-02-11
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] Unique properties of muscle-specific calpain and muscular dystrophy caused by its defect.2011
- Author(s)
  Sorimachi, H., Ojima, K., and Ono, Y.
- Organizer
  IPS2011 - Seventh General Meeting of the International Proteolysis Society
- Place of Presentation
  San Diego, USA.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Calpain-3/p94のNa依存性について2011
- Author(s)
  小野弥子
- Organizer
  平成22年度科学研究費補助金特定領域研究「タンパク質分解による細胞・個体機能の制御」班会議
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] Structural functions of skeletal muscle-specific calpain in Ca2+ efflux from the sarcoplasmic reticulum2011
- Author(s)
  Koichi Ojima, Yasuko Ono, Coen Ottenheijm, Shoji Hata, Hidenori Suzuki, Mika Oe, Ikuyo Nakajima, Susumu Muroya, Henk Granzier, and Hiroyuki Sorimachi
- Organizer
  2011 Annual Meeting of the American Society for Cell Biology.
- Place of Presentation
  Denver, CO. (USA)
- Data Source
  KAKENHI-PROJECT-23500477
[Presentation] Skeletal muscle-specific calpain is an intracellular Ca^<2+> and Na^+-dependent protease.2011
- Author(s)
  Sorimachi, H., Ojima, K., Takaya, E., and Ono Y.
- Organizer
  CaBP17 - The 17th International Symposium on Ca^<2+>-binding proteins and Ca^<2+> function in health and disease.
- Place of Presentation
  Beijing, China.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Structure-Function relationship of Na^+-dependent activity of calpain-3/p942011
- Author(s)
  Ono, Y., Takaya, E., Doi, N., Kitamura, F., Sorimachi, H
- Organizer
  The 17th Symposium on Ca^<2+>-Binding Proteins and Ca^<2+> Function in Health and Disease
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] Characteristics of p94/calpain 3 as an intracellular Na^+-dependent protease2010
- Author(s)
  Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H.
- Organizer
  FASEB Summer Research Conferences
- Place of Presentation
  Carefree, AZ(米国)
- Year and Date
  2010-07-28
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] Unique functions of mammalian unconventional calpains.2010
- Author(s)
  Sorimachi, H., Hata, S., Ojima, K., Labeit, S., and Ono, Y.
- Organizer
  FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
- Place of Presentation
  Arizona, USA.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Functions of calpain-3/p94 indicated by its unique properties2010
- Author(s)
  Ono, Y.
- Organizer
  CHUV (Le Centre Hospitalier Universitaire Vaudois) Special Seminar
- Place of Presentation
  CHUV大学(スイス)(招待講演)
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] Functions of calpain-3/p94 indicated by its unique properties2010
- Author(s)
  Ono, Y
- Organizer
  CHUV (Le Centre Hospitalier Universitaire Vaudois) Special Seminar
- Place of Presentation
  Lausanne, Switzerland
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] Skeletal muscle-specific calpain, p94/calpain-3, dynamically distributes in skeletal muscle cells to adapt to physical stress, defects of which cause muscular dystrophy.2010
- Author(s)
  Ono Y., Ojima K., Torii F., Takaya E., Doi N., Nakagawa K., Hata S., Abe K., Sorimachi H.
- Organizer
  15th International Congress of the World Muscle Society
- Place of Presentation
  Kumamoto, Japan
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-20370055
[Presentation] Skeletal muscle-specific calpain, p94/calpain-3, is an intracellular Na^+-dependent protease2010
- Author(s)
  Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H
- Organizer
  XIIth Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  Portoroz, Slovenia
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] p94/calpain3自己消化機構の解析, Inter/Intra molecular interaction involved in the autocatalytic proteolysis of p94/calpain 32010
- Author(s)
  小野弥子,土井奈穂子,高谷恵美,北村ふじ子,反町洋之
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] 鈴木紘一先生追悼講演「CANPからカルパインそしてCAPNへ」2010
- Author(s)
  小野弥子,秦勝志,川原裕之,前田達哉,反町洋之
- Organizer
  日本病態プロテアーゼ学会第15回大会
- Place of Presentation
  大阪
- Year and Date
  2010-08-20
- Data Source
  KAKENHI-PROJECT-20370055
[Presentation] Calpains-introduction2010
- Author(s)
  Ono, Y., Hata, S., and Sorimachi, H.
- Organizer
  CHUV(Le Centre Hospitalier Universitaire Vaudois) Special Seminar
- Place of Presentation
  Lausanne, Swizerland.
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] [Selected for oral presentation] Skeletal muscle-specific calpain, p94/calpain-3, dynamically distributes in skeletal muscle cells to adapt to physical stress, defects of which cause muscular dystrophy.2010
- Author(s)
  Ojima K., Ono Y., Doi N., Kitamura F., Hata S., Kawabata Y., Suzuki K., Maeda T., Abe K., Nakao H., Aiba A., Nakao K., Suzuki H., Kawahara H., Witt C., Labeit S., Ottenheijm, C., Granzier H., Toyama-Sorimachi N., Sorimachi M., Sorimachi H.
- Organizer
  15th International Congress of the World Muscle Society
- Place of Presentation
  Kumamoto, Japan
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-20370055
[Presentation] Characteristics of p94/calpain-3 as an intracellular Na^+-dependent protease2010
- Author(s)
  Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., and Sorimachi, H
- Organizer
  FASEB Summer Research Conferences . Biology of the calpains in Health and Disease, Carefree, AZ
- Place of Presentation
  USA
- Year and Date
  2010-07-28
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] (Selected for oral presentation) Characteristics of p94/calpain 3 as an intracellular Na^+-dependent protease2010
- Author(s)
  Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., and Sorimachi, H.
- Organizer
  FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
- Place of Presentation
  Arizona, USA.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Calpains-introduction CHUV (Le Centre Hospitalier Universitaire Vaudois) Special Seminar2010
- Author(s)
  小野弥子, 秦勝志, 反町洋之
- Place of Presentation
  Lausanne, Swizerland
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-20370055
[Presentation] Redundant and non-redundant effects of Ca^<2+> and Na^+ on the activation of p94/calpain 32010
- Author(s)
  Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H
- Organizer
  The 15th International Congress of the World Muscle Society
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] Skeletal muscle-specific calpain, p94/calpain-3, is an intracellular Na^+-dependent protease2010
- Author(s)
  Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H.
- Organizer
  XIIth Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  Portoroz(スロベニア)
- Year and Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] p94/calpain3自己消化機構の解析2010
- Author(s)
  小野弥子、土井奈穂子、高谷恵美、北村ふじ子、反町洋之
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] [The closing lecture] Unique functions of mammalian unconventional calpains.2010
- Author(s)
  Sorimachi H., Hata S., Ojima K., Labeit S., Ono Y.
- Organizer
  FASEB Summer Research Conferences-The Biology of Calpains in Health & Disease
- Place of Presentation
  Arizona, USA
- Year and Date
  2010-07-30
- Data Source
  KAKENHI-PROJECT-20370055
[Presentation] The closing lecture]In Memoriam Koichi Suzuki: Calpains in muscles and stomach XIIth Symposium on Proteases2010
- Author(s)
  Ono, Y., Hata, S., Ojima, K., Tonami, K., Kitamura, F., Ueno, M., Takaya, E., Granzier, H., Labeit, S., and Sorimachi, H.
- Organizer
  Inhibitors and Biological Control
- Place of Presentation
  Portoroz, Slovenia.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Calpain3/p94自己消化機構の解析2010
- Author(s)
  小野弥子, 土井奈穂子, 高谷恵美, 北村ふじ子, 反町洋之
- Organizer
  BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  ポートピアホテル(神戸)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] [The closing lecture] In Memoriam Koichi Suzuki : Calpains in muscles and stomach2010
- Author(s)
  Ono Y., Hata S., Ojima K., Tonami K., Kitamura F., Ueno M., Takaya E., Granzier H., Labeit S., Sorimachi H.
- Organizer
  12^<th> Symposium on Proteases, Inhibitors and Biological Control
- Place of Presentation
  Portoroz, Slovenia
- Year and Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-20370055
[Presentation] Calpain3/p94自己消化機構の解析2010
- Author(s)
  小野弥子,土井奈穂子,高谷恵美,北村ふじ子,反町洋之
- Organizer
  BMB2010 (第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22770139
[Presentation] Calpain-3 and molecular interactions.2009
- Author(s)
  Sorimachi H., Ojima K., Hata S., Ono Y.
- Organizer
  Calpaines et Calpainopathies. VII^<es> Journees annuelles de la Societe Francaise de Myologie
- Place of Presentation
  Hendaye, France
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-20370055
[Presentation] Calpain-3 and molecular interactions. Calpaines et Calpainopathies.2009
- Author(s)
  Sorimachi, H., Ojima, K., Hata, S., andOno, Y.
- Organizer
  VIIes Journees annuelles de la SFM(Societe Francaise de Myologie)
- Place of Presentation
  Hendaye, France.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] カルパインの多彩な生理機能とその破綻による病態2009
- Author(s)
  反町洋之,小野弥子,秦勝志,尾嶋孝一
- Organizer
  第82回日本生化学会大会シンポジウム「プロテオリシスの多彩な生理機能とその破綻による病態」
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20370055
[Presentation] カルパイン及びコネクチンの構造-病態生理相関(Structure-Pathophysiological-Function Relationships of Calpain and Connectin/Titin.)2008
- Author(s)
  反町洋之、小野弥子、尾嶋孝一、林智佳子、土井奈穂子、北村ふじ子、小山傑、楠畑かおり、秦勝志、Labeit, S.
- Organizer
  第8回日本蛋白質科学会年会シンポジウム「蛋白質の輪廻転生-セントラルドグマを超えて」
- Place of Presentation
  東京
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Roles of skeletal muscle-specific calpain, p94/calpain 3, on multiple molecular interactions using connectin/titin N2A region as a modulating scaffold2008
- Author(s)
  Sorimachi, H., Hayashi, C., Hata, S., Ojima, K., Koyama, S., Doi, N., Kitamura, F., Takaya, E., Ueno, M., Kaneko, N., Ono, Y.
- Organizer
  11th International Symposium on PROTEINASE INHIBITORS AND BIOLOGICAL CONTROL
- Place of Presentation
  Portoroz, Slovenia
- Year and Date
  2008-09-02
- Data Source
  KAKENHI-PROJECT-20370055
[Presentation] Analysis of structure-function relationships of p94 by proteinase-trapping system2008
- Author(s)
  Ono, Y
- Organizer
  The Joint 4th AOHUP (Asian Oceania Human Proteome Organisation) and 2nd PRICPS (Pacific Rim International Conference on Protein Science)
- Place of Presentation
  Cairns, Australia
- Year and Date
  2008-06-22
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Roles of skeletal muscle-specific calpain, p94/calpain 3, on multiple molecular interactions using connectin/titin N2A region as a modulating scaffold.2008
- Author(s)
  Sorimachi H., Hayashi C., Hata S., Ojima K., Koyama S., Doi N., Kitamura F., Takaya E., Ueno M., Kaneko N., Ono Y.
- Organizer
  11^<th> International Symposium on Proteinase Inhibitors and Biological Control
- Place of Presentation
  Portoroz, Slovenia
- Year and Date
  2008-09-02
- Data Source
  KAKENHI-PROJECT-20370055
[Presentation] Roles of skeletal muscle-specific calpain, p94/calpain 3, on multiple molecular interactions using connectin/titin N2A region as a modulating scaffold.2008
- Author(s)
  Sorimachi, H., Hayashi, C., Hata, S., Ojima, K., Koyama, S., Doi, N., Kitamura, F., Takaya, E., Ueno, M., Kaneko, N., and Ono, Y.
- Organizer
  11th International Symposium on PROTEINASE INHIBITORS AND BIOLOGICAL CONTROL
- Place of Presentation
  Portoroz, Slovenia.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Toward Understanding Relationships between Proteolytic Activity of Skeletal Muscle-Specific Calpain and Calpainopathy.2007
- Author(s)
  Ono, Y., Ojima, K., Hata, S., and Sorimachi, H.
- Organizer
  2007 Korea-Japan Joint Symposium "Protein Modification and Degradation in Human Diseases"
- Place of Presentation
  Seoul, South Korea.
- Year and Date
  2007-09-05
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Unconventional calpains.2007
- Author(s)
  Ono, Y., Ojima, K., Hayashi, C., Doi, N., Kitamura, F., Koyama, S., Hata, S., Labeit, S., Yanagida, M., Maeda, T., and Sorimachi, H.
- Organizer
  FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
- Place of Presentation
  Colorado, USA.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Comprehensive survey of p94/calpain 3 substrates by comparafive proteomics.2007
- Author(s)
  Ono.Y., Hayasly, C., Doi, N., Kitamura, F., Shindo, M., Kenichi Kudo, Tsubata, T., Yanagida, M., and Sorimachi, H.
- Organizer
  FASEB Summer Research Conferences-The Biology of Calpainsin Health & Disease
- Place of Presentation
  Colorado,USA
- Year and Date
  2007-07-15
- Data Source
  KAKENHI-PROJECT-18770124
[Presentation] Novel approaches for analysis of proteolytic activity of muscle-specific calpain p94/calpain 32007
- Author(s)
  Ono, Y., Ojima, K., Hayashi, C., Doi, N., Kitamura, F., Koyama, S., Hata, S., Labeit, S., Yanagida, M., Maeda, T., and Sorimachi, H.
- Organizer
  Xth International Symposium on PROTEINASE INHIBITORS AND BIOLOGICAL CONTROL: From single molecules to degradomics
- Place of Presentation
  Portoroz, Slovenia.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] How do defects in proteolytic functions of skeletal muscle-specific calpain, p94/calpain 3, cause calpainopathy/LGMD2A?2006
- Author(s)
  Sorimachi, H., Ojima, K., Yanagida, M., Ogawa, H., Hayashi, C., Doi, N., and Ono, Y.
- Organizer
  XIth International Congress on Neuromuscular Diseases
- Place of Presentation
  Istanbul, Turkey.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] A novel genetic assay system for a rapidly autolyzing muscle-specific calpain p94/calpain 32006
- Author(s)
  Ono, Y., Torii, F., Ojima, K., Doi, N., Yoshioka, K., Kawabata, Y., Labeit, D., Labeit, S., Suzuki, K., Abe, K., Maeda, T., Hata, S., Koyama, S., and Sorimachi, H.
- Organizer
  5^<th> Internationla Conference on Cysteine Proteinases and Their Inhitbitors: From Structure to Regulation and Biology
- Place of Presentation
  Portoroz, Slovenia.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Extended concept for calpain “activity” – non-proteolytic functions of unconventional calpains.
- Author(s)
  Sorimachi, H., Tonami, K., Shinkai-Ouchi, F., Hata, S., Ojima, K., and Ono, Y.
- Organizer
  FASEB Summer Research Conferences – Biology of Calpains in Health & Disease
- Place of Presentation
  Vermont, USA.
- Year and Date
  2013-07-21 – 2013-07-26
- Invited
- Data Source
  KAKENHI-PROJECT-23247021
[Presentation] 筋特異的カルパインCAPN3/p94の新奇活性化機構の解析
- Author(s)
  小野弥子
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22770139

1. SORIMACHI Hiroyuki (10211327)

# of Collaborated Projects: 5 results

# of Collaborated Products: 92 results
2. HATA Shoji (10392375)

# of Collaborated Projects: 5 results

# of Collaborated Products: 49 results
3. OJIMA Koichi (60415544)

# of Collaborated Projects: 2 results

# of Collaborated Products: 37 results
4. MATSUOKA Kunie (40291158)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TONAMI Kazuo (70511393)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. SHINKAI-OUCHI Fumiko (00435710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. 宮崎拓郎 (80398693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 佐竹炎 (20280688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 松本英成 (30861132)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SHINDO Mayumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
11. ITOH Yoshiki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 大西紘二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 柴田秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 牧正敏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ono yasuko 小野 弥子

ONO Yasuko 小野 弥子

小野 弥子 オノ ヤスコ

Research Projects

Research Products

Co-Researchers

筋特異的カルパインの構造と局在変化による多機能性の解明Principal Investigator

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Homeostatic regulation of metabolic organs by splicing factors and its clinical application

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Characterization of structure dependent CAPN7 activityPrincipal Investigator

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Elucidation of molecular mechanism of limb-girdle muscular dystrophy through comparative analysis of calpain-3 mutant mice

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The role of CAPN7 in the adaptation to environmental changePrincipal Investigator

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Tissue-specific functional studies on calpains

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Developing sensor-proteins to detect CAPN3 protease activity

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Functional aspect of skeletal muscle-specific calpain systemPrincipal Investigator

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Novel functions of evolutionarily conserved calpain-7/PalBH in membrane trafficking system.

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Biomodulation by calpain

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骨格筋におけるカルパインシステムの役割と制御機構の解析Principal Investigator

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カルパインによる筋細胞監視システムとその破綻による筋ジストロフィー

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[Book] In "Encyclopedia of Biological Chemistry 2^<nd> Edition2013

Author(s)

ono yasuko 小野弥子

ONO Yasuko 小野弥子

小野弥子オノヤスコ