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ono yasuko  小野 弥子

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… Alternative Names

ONO Yasuko  小野 弥子

小野 弥子  オノ ヤスコ

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Researcher Number 20392376
Other IDs
Affiliation (Current) 2025: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 副参事研究員
Affiliation (based on the past Project Information) *help 2021 – 2024: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 副参事研究員
2020: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, プロジェクトリーダー
2018 – 2019: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 副参事研究員
2017: 公益財団法人 東京都医学総合研究所, 生体分子先端研究分野, 副参事研究員
2016: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 副参事研究員 … More
2013 – 2015: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主席研究員
2014: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 主席研究員
2011: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主席研究員
2010: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員
2010: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主席研究員
2008: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員
2007: 東京都臨床医学総合研究所, 主任研究員
2007: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 主任研究員
2005 – 2006: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 Less
Review Section/Research Field
Principal Investigator
Functional biochemistry / Basic Section 43030:Functional biochemistry-related / Basic Section 44010:Cell biology-related
Except Principal Investigator
Functional biochemistry / Biological Sciences / Basic Section 59040:Nutrition science and health science-related / Pathological medical chemistry / Neurophysiology and muscle physiology
Keywords
Principal Investigator
カルパイン / プロテアーゼ / 骨格筋 / 筋ジストロフィー / サルコメア / プロテオーム解析 / タンパク質分解 / 機能制御 / ストレス応答 / CBSWドメイン … More / ほ乳類 / タンパク質間相互作用 / ドメイン構造 / プロテアーゼ複合体 / ノックイン / ドメイン / 相互作用タンパク質 / 致死 / ノックアウト / マウス / タンパク質代謝 / ノックアウトマウス / 進化的保存性 / 細胞内局在 / 相互作用検出 / 致死性 / タンパク質相互作用 / プロテオーム / ノックインマウス / 自己消化活性 / 分解断片の定量 / MS / LC-MS / タンパク質発現系 / 骨格筋のストレス応答系 / MARP(筋アンキリンリピートタンパク質 / 活性制御 / mdmマウス / タイチン / コネクチン / カルパイン3 / p94 … More
Except Principal Investigator
カルパイン / 骨格筋 / プロテオリシス / 筋ジストロフィー / 酵素 / メンブレン・トラフィック / 蛋白質 / 胃腸 / カルシウム / 細胞内タンパク質分解 / シグナル伝達 / ユビキチンリガーゼ / ノックインマウス / モジュレータ・プロテアーゼ / 死細胞クリアランス / 肥満 / マクロファージ / mRNAスプライシング / ノックアウトマウス / 肢帯型筋ジストロフィー2A / プロテオーム解析 / プロテオミクス / カルパイン3 / 肢帯型筋ジストロフィー / 骨格筋の分化成熟 / 筋線維型 / カルパイン3 / 筋成熟遅滞 / カルパイン-3 / 肢帯型筋ジストロフィー2A型 / プロテアーゼ / 遺伝子改変マウス / 組織特異的発現 / 基質特異性 / 酵素学 / 自己消化 / 胃腸疾患 / 質量分析 / 内膜輸送系 / コネクチン / タンパク質 Less
  • Research Projects

    (12 results)
  • Research Products

    (164 results)
  • Co-Researchers

    (13 People)
  •  筋特異的カルパインの構造と局在変化による多機能性の解明Principal Investigator

    • Principal Investigator
      小野 弥子
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Homeostatic regulation of metabolic organs by splicing factors and its clinical application

    • Principal Investigator
      宮崎 拓郎
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Showa University
  •  Characterization of structure dependent CAPN7 activityPrincipal Investigator

    • Principal Investigator
      ONO Yasuko
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Elucidation of molecular mechanism of limb-girdle muscular dystrophy through comparative analysis of calpain-3 mutant mice

    • Principal Investigator
      SHINKAI-OUCHI Fumiko
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  The role of CAPN7 in the adaptation to environmental changePrincipal Investigator

    • Principal Investigator
      ONO Yasuko
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Tissue-specific functional studies on calpains

    • Principal Investigator
      SORIMACHI Hiroyuki
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Developing sensor-proteins to detect CAPN3 protease activity

    • Principal Investigator
      OJIMA Koichi
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      National Agriculture and Food Research Organization
  •  Functional aspect of skeletal muscle-specific calpain systemPrincipal Investigator

    • Principal Investigator
      ONO Yasuko
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      公益財団法人東京都医学総合研究所
      Tokyo Metropolitan Organization for Medical Research
  •  Novel functions of evolutionarily conserved calpain-7/PalBH in membrane trafficking system.

    • Principal Investigator
      SORIMACHI Hiroyuki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Biomodulation by calpain

    • Principal Investigator
      SORIMACHI Hiroyuki
    • Project Period (FY)
      2006 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      財団法人東京都医学研究機構
      Tokyo Metropolitan Organization for Medical Research
  •  骨格筋におけるカルパインシステムの役割と制御機構の解析Principal Investigator

    • Principal Investigator
      小野 弥子
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  カルパインによる筋細胞監視システムとその破綻による筋ジストロフィー

    • Principal Investigator
      SORIMACHI Hiroyuki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book Other

  • [Book] In "Encyclopedia of Biological Chemistry 2^<nd> Edition2013

    • Author(s)
      Sorimachi, H., Hata, S., and Ono, Y. Calpain
    • Total Pages
      3232
    • Publisher
      Elsevier, Oxford; eds., M.D. Lane and W. J. Lennarz
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Book] Chapter 471: μ-calpain, Chapter 472: m-calpain, Chapter 473: Muscle calpain, Chapter 474: Gastrointestinal calpain, Chapter 476: Other calpains. in: Handbook of Proteolytic enzymes, 3rd Edition. N.D. RawlIngs, G. Salvesen, editors2013

    • Author(s)
      Sorimachi, H., Hata, S., Ono, Y
    • Total Pages
      3932
    • Publisher
      Elsevier Academic Press (Oxford)
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Book] 「カルパイン」,モデル動物利用マニュアル…<生物機能モデルと新しいリソース・リサーチツール>2011

    • Author(s)
      反町洋之,秦勝志,小野弥子
    • Total Pages
      671
    • Publisher
      株式会社LIC
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Book] 骨格筋特異的カルパイン-3の活性制御因子は細胞内Na+~例外か多様性か(化学と生物 49-4))2011

    • Author(s)
      小野弥子
    • Total Pages
      3
    • Publisher
      学会出版センター
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Journal Article] Cryptic splicing events result in unexpected protein products from calpain-10 (CAPN10) cDNA2022

    • Author(s)
      Ono Yasuko、Doi Naoko、Shindo Mayumi、Panico Pablo、Salazar Ana Maria
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

      Volume: 1869 Issue: 3 Pages: 119188-119188

    • DOI

      10.1016/j.bbamcr.2021.119188

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06236
  • [Journal Article] Enyzmes | Calpains2021

    • Author(s)
      Ono Yasuko、Shinkai-Ouchi Fumiko、Noguchi Aya、Hata Shoji
    • Journal Title

      Encyclopedia of Biological Chemistry

      Volume: 3 Pages: 280-291

    • DOI

      10.1016/b978-0-12-819460-7.00330-3

    • ISBN
      9780128220405
    • Open Access
    • Data Source
      KAKENHI-PROJECT-18K06236
  • [Journal Article] A muscle-specific calpain, CAPN3, forms a homotrimer2020

    • Author(s)
      Hata Shoji、Doi Naoko、Shinkai-Ouchi Fumiko、Ono Yasuko
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

      Volume: 1868 Issue: 7 Pages: 140411-140411

    • DOI

      10.1016/j.bbapap.2020.140411

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06236, KAKENHI-PROJECT-20K07044
  • [Journal Article] Calpain-2 participates in the process of calpain-1 inactivation.2020

    • Author(s)
      Shinkai-Ouchi F, Shindo M, Doi N, Hata S, Ono Y
    • Journal Title

      Bioscience Report

      Volume: 40 Issue: 11

    • DOI

      10.1042/bsr20200552

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06236, KAKENHI-PROJECT-20K07044
  • [Journal Article] Developing fluorescence sensor probe to capture activated muscle-specific calpain-3 (CAPN3) in living muscle cells2020

    • Author(s)
      Ojima K, Hata S, Shinkai-Ouchi F, Oe M, Muroya S, Sorimachi H, Ono Y
    • Journal Title

      Biology Open

      Volume: 9

    • DOI

      10.1242/bio.048975

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06236, KAKENHI-PROJECT-20K07044, KAKENHI-PROJECT-19H04014
  • [Journal Article] Elucidation of the molecular mechanism of disease development due to calpain dysfunction-CALPAIN.2018

    • Author(s)
      Sorimachi H, Ono Y, Hata S, Shimakai-Ouchi F
    • Journal Title

      Impact

      Volume: 2018 Issue: 2 Pages: 74-76

    • DOI

      10.21820/23987073.2018.2.74

    • Open Access
    • Data Source
      KAKENHI-PROJECT-26450172, KAKENHI-PROJECT-26670166
  • [Journal Article] Predictions of Cleavability of Calpain Proteolysis by Quantitative Structure-Activity Relationship Analysis Using Newly Determined Cleavage Sites and Catalytic Efficiencies of an Oligopeptide Array.2016

    • Author(s)
      Shinkai-Ouchi F, Koyama S, Ono Y, Hata S, Ojima K, Shindo M, duVerle D, Ueno M, Kitamura F, Doi N, Takigawa I, Mamitsuka H, Sorimachi H.
    • Journal Title

      Mol Cell Proteomics

      Volume: 15 Issue: 4 Pages: 1262-1280

    • DOI

      10.1074/mcp.m115.053413

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25440059, KAKENHI-PROJECT-26450172, KAKENHI-PROJECT-26670166, KAKENHI-PROJECT-15H02389
  • [Journal Article] Calpain research for drug discovery: challenges and potential.2016

    • Author(s)
      Ono Y, Saido TC, Sorimachi H
    • Journal Title

      Nat Rev Drug Discov

      Volume: 15 Issue: 12 Pages: 854-876

    • DOI

      10.1038/nrd.2016.212

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H02389, KAKENHI-PROJECT-25440059
  • [Journal Article] An eccentric calpain, CAPN3/p94/calpain-3.2016

    • Author(s)
      Ono, Y., Ojima, K., Shinkai-Ouchi, F., Hata, S., and Sorimachi, H.
    • Journal Title

      Biochimie

      Volume: 122 Pages: 169-87

    • DOI

      10.1016/j.biochi.2015.09.010

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25440059, KAKENHI-PROJECT-26670166, KAKENHI-PROJECT-15H02389, KAKENHI-PROJECT-26450172
  • [Journal Article] Involvement of calpain-7 in epidermal growth factor receptor degradation via the endosomal sorting pathway2014

    • Author(s)
      Yuki Maemoto, Yasuko Ono, Satomi Kiso, Hideki Shibata, Terunao Takahara, Hiroyuki Sorimachi, Masatoshi Maki
    • Journal Title

      The FEBS Journal

      Volume: 281 Issue: 16 Pages: 3642-3655

    • DOI

      10.1111/febs.12886

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24580138, KAKENHI-PROJECT-25440059
  • [Journal Article] Muscle-specific calpain-3 is phosphorylated in its unique insertion region for enrichment in a myofibril fraction2014

    • Author(s)
      Ojima, K. Ono, Y. Hata, S. Noguchi, S. Nishino, I. Sorimachi, H.
    • Journal Title

      Genes to Cells

      Volume: 19 Issue: 11 Pages: 830-841

    • DOI

      10.1111/gtc.12181

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23500477, KAKENHI-PROJECT-26450172
  • [Journal Article] The N- and C-terminal autolytic fragments of CAPN3/p94/calpain-3 restore proteolytic activity by intermolecular complementation.2014

    • Author(s)
      Ono, Y., Shindo, M., Doi, N., Kitamura, F., Gregorio, C. C., and Sorimachi, H.
    • Journal Title

      Proc. Natl. Acad. Sci. U. S. A.

      Volume: 111 Issue: 51

    • DOI

      10.1073/pnas.1411959111

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23247021
  • [Journal Article] PLEIAD/SIMC1/C5orf25, a Novel Autolysis Regulator for a Skeletal-Muscle-Specific Calpain, CAPN3, Scaffolds a CAPN3 Substrate, CTBP12013

    • Author(s)
      Ono, Y., Iemura, SI., Novak, S. M., Doi, N., Kitamura, F., Natsume, T., Gregorio, C. C., Sorimachi H
    • Journal Title

      J. Mol. Biol

      Volume: (in press) Issue: 16 Pages: 2955-2972

    • DOI

      10.1016/j.jmb.2013.05.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770139, KAKENHI-PLANNED-24115007
  • [Journal Article] Calpain-6 deficiency promotes skeletal muscle development and regeneration.2013

    • Author(s)
      Tonami, K., Hata, S., Ojima, K., Ono, Y., Kurihara, Y., Amano, T., Sato, T., Kawamura, Y., Kurihara, H., Sorimachi, H.
    • Journal Title

      PLOS Genetics

      Volume: 9 Issue: 8 Pages: 1003668-1003668

    • DOI

      10.1371/journal.pgen.1003668

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-11J02638, KAKENHI-PROJECT-23247021, KAKENHI-PROJECT-23590326, KAKENHI-PROJECT-23780152, KAKENHI-PUBLICLY-24115705, KAKENHI-PROJECT-24249047
  • [Journal Article] Understanding the substrate specificity of conventional calpains2012

    • Author(s)
      Sorimachi, H., Mamitsuka, H., Ono, Y
    • Journal Title

      Biol. Chem

      Volume: 393 Issue: 9 Pages: 853-871

    • DOI

      10.1515/hsz-2012-0143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
  • [Journal Article] Calpains - An elaborate proteolytic system2012

    • Author(s)
      Ono Y, Sorimachi H
    • Journal Title

      Biochim Biophys Acta

      Volume: 1824 Issue: 1 Pages: 224-236

    • DOI

      10.1016/j.bbapap.2011.08.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
  • [Journal Article] Regulation and physiological roles of the calpain system in muscular disorders2012

    • Author(s)
      Sorimachi, H., Ono, Y
    • Journal Title

      Cardiovasc. Res

      Volume: 96 Issue: 1 Pages: 11-22

    • DOI

      10.1093/cvr/cvs157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
  • [Journal Article] Chapter 453-6 and 458. μ-calpain, m-calpain, Muscle calpain, Gastrointestinal calpain, and other calpains.2012

    • Author(s)
      Sorimachi H, Ono Y, Hata S
    • Journal Title

      Handbook of Proteolytic enzymes, 3rd Edition(Rawlings ND, Salvesen G, eds)(Oxford, UK: Elsevier Academic Press.)

      Volume: in press

    • URL

      http://store.elsevier.com/product.jsp?Isbn=9780123822192&pagename=search

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Does the severity of the LGMD2A phenotype in compound heterozygotes depend on the combination of mutations?2011

    • Author(s)
      Saenz A., Ono Y., Sorimachi H., Goicoechea M., Leturcq F., Blazquez L., Garcia-Bragado F., Marina A., Poza J.J., Azpitarte M., Doi N., Urtasun M., Kaplan J.C., Lopez de Munain A.
    • Journal Title

      Muscle Nerve (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] 肢帯型筋ジストロフィーの発症機構2011

    • Author(s)
      反町洋之、小野弥子
    • Journal Title

      生体の科学 62(in press)

    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Calpain cleavage prediction using multiple kernel learning.2011

    • Author(s)
      duVerle D. A., Ono Y., Sorimachi H., Mamitsuka H.
    • Journal Title

      PLoS One (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Calpain cleavage prediction using multiple kernel learning.2011

    • Author(s)
      duVerle DA, Ono Y, Sorimachi H, Mamitsuka H
    • Journal Title

      PLoS One

      Volume: 6 Issue: 5 Pages: e19035-e19035

    • DOI

      10.1371/journal.pone.0019035

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139
  • [Journal Article] 肢帯型筋ジストロフィーの発症機構2011

    • Author(s)
      反町洋之,小野弥子
    • Journal Title

      生体の科学

      Volume: 62-2 Pages: 95-99

    • Data Source
      KAKENHI-PROJECT-22770139
  • [Journal Article] Calpain chronicle-an enzyme family under multidisciplinary characterization2011

    • Author(s)
      Sorimachi, H., Hata, S., Ono, Y
    • Journal Title

      Proc Jpn Acad Ser B Phys Biol Sci

      Volume: 87 Pages: 287-327

    • NAID

      130000903736

    • URL

      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153876/

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Journal Article] Calpain chronicle-an enzyme family under multidisciplinary characterization.2011

    • Author(s)
      反町洋之, 秦勝志, 小野弥子
    • Journal Title

      Proc.Jpn.Acad.Ser.B 87(in press)

    • NAID

      130000903736

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] カルパインの組織機能論2011

    • Author(s)
      反町洋之,秦勝志,小野弥子
    • Journal Title

      実験医学

      Volume: 29 Pages: 1882-1890

    • Data Source
      KAKENHI-PROJECT-22770139
  • [Journal Article] Does the severity of the LGMD2A phenotype in compound heterozygotes depend on the combination of mutations?2011

    • Author(s)
      Saenz A, Ono Y, Sorimachi H, Goicoechea M, Leturcq F, Blazquez L, Garcia-Bragado F, Marina A, Poza JJ, Azpitarte M, Doi N, Urtasun M, Kaplan JC, Lopez de Munain A
    • Journal Title

      Muscle and Nerve

      Volume: 44 Issue: 5 Pages: 710-714

    • DOI

      10.1002/mus.22194

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
  • [Journal Article] 骨格筋特異的カルパイン-3の活性制御因子は細胞内Na^+~例外か多様性か2011

    • Author(s)
      小野弥子,反町洋之
    • Journal Title

      化学と生物 49

      Pages: 229-231

    • NAID

      10028117186

    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Calpain chronicle--an enzyme family under multidisciplinary characterization.2011

    • Author(s)
      Sorimachi H, HataS, Ono Y
    • Journal Title

      Proc Jpn Acad Ser B Phys Biol Sci

      Volume: 87 Pages: 287-327

    • NAID

      130000903736

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Impact of genetic insights into calpain biology2011

    • Author(s)
      Sorimachi H, Hata S, Ono Y
    • Journal Title

      J Biochem

      Volume: 150 Issue: 1 Pages: 23-37

    • DOI

      10.1093/jb/mvr070

    • NAID

      10030586192

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139
  • [Journal Article] Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles.2011

    • Author(s)
      Ojima K., Ono Y., Ottenheijm C., Hata S., Suzuki H., Granzier H., Sorimachi H.
    • Journal Title

      J.Mol.Biol. 407

      Pages: 439-449

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles.2011

    • Author(s)
      Ojima K, Ono Y, Ottenheijm C, HataS, Suzuki H, Granzier H, Sorimachi H
    • Journal Title

      J Mol Biol

      Volume: 407 Issue: 3 Pages: 439-449

    • DOI

      10.1016/j.jmb.2011.01.057

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
  • [Journal Article] カルパインの組織機能論2011

    • Author(s)
      反町洋之、秦勝志、小野弥子
    • Journal Title

      実験医学 29(in press)

    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] 骨格筋特異的カルパイン-3の活性制御因子は細胞内Na^+~例外か多様性か2011

    • Author(s)
      小野弥子,反町洋之
    • Journal Title

      化学と生物

      Volume: 49-4 Pages: 229-231

    • NAID

      10028117186

    • Data Source
      KAKENHI-PROJECT-22770139
  • [Journal Article] Skeletal muscle-specific calpain is an intracellular Na+-dependent protease.2010

    • Author(s)
      Ono Y., Ojima K., Torii F., Takaya E., Doi N., Nakagawa K., Hata S., Abe K., Sorimachi H.
    • Journal Title

      J.Biol.Chem. 285

      Pages: 22986-22998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy.2010

    • Author(s)
      Ojima K, Kawabata Y, Nakao H, Nakao K, Doi N, Kitamura F, Ono Y, HataS, Suzuki H, Kawahara H, Bogomolovas J,Will C, Ottenheijm C, LabeitS, Granzier H, Toyama-Sorimachi N, Sorimachi M, Suzuki K, Maeda T, Abe K, Aiba A, Sorimachi H
    • Journal Title

      J Clin Invest

      Volume: 120 Issue: 8 Pages: 2672-2683

    • DOI

      10.1172/jci40658

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22300106, KAKENHI-PROJECT-22770139
  • [Journal Article] Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy2010

    • Author(s)
      Ojima, K., Kawabata, Y., Nakao, H., Nakao, K., Doi, N., Kitamura, F., Ono, Y., Hata, S., Suzuki, H., Kawahara, H., Bogomolovas, J., Witt, C., Ottenheijm, C., Labeit, S., Granzier, H., Toyama-Sorimachi, N., Sorimachi, M., Suzuki, K., Maeda, T., Abe, K., Aiba, A., Sorimachi, H.
    • Journal Title

      J.Clin.Invest.

      Volume: 120 Pages: 2672-2683

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Redundant and non-redundant effects of Ca^<2+> and Na^+ on the activation of p94/calpain-3.2010

    • Author(s)
      Ono, Y.
    • Journal Title

      Neuromuscul. Disord.

      Volume: 20 Pages: 608-608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Expanding members and roles of the calpain superfamily and their genetically modified animals.2010

    • Author(s)
      Sorimachi H, Hata S, Ono Y
    • Journal Title

      Exp Anim

      Volume: 59 Pages: 549-566

    • NAID

      130000419250

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21030783

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Skeletal muscle-specific calpain is an intracellular Na^+-dependent protease.2010

    • Author(s)
      Ono Y, Ojima K, Torii F, Takaya E, Doi N, Nakagawa K, Hata S, Abe K, Sorimachi H
    • Journal Title

      J Biol Chem

      Volume: 285 Issue: 30 Pages: 22986-22998

    • DOI

      10.1074/jbc.m110.126946

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139
  • [Journal Article] CaMPDB: a resource for calpain and modulatory proteolysis.2010

    • Author(s)
      duVerle DA, Takigawa I, Ono Y, Sorimachi H, Mamitsuka H
    • Journal Title

      Genome Inform

      Volume: 22 Pages: 202-213

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Skeletal muscle-specific calpain is an intracellular Na^+-dependent protease2010

    • Author(s)
      Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H.
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 22986-22998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Journal Article] Expanding members and roles of the calpain superfamily and their genetically modified animals.2010

    • Author(s)
      反町洋之, 秦勝志, 小野弥子
    • Journal Title

      Exp.Anim. 59

      Pages: 549-566

    • NAID

      130000419250

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Skeletal muscle-specific calpain is an intracellular Na^+-dependent protease2010

    • Author(s)
      Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H.
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 22986-22998

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Skeletal muscle-specific calpain, p94/calpain-3, dynamically distributes in skeletal muscle cells to adapt to physical stress, defects of which cause muscular dystrophy.2010

    • Author(s)
      Ojima K, Ono Y, Doi N, Kitamura F, Kawabata Y, Suzuki K, Maeda T, Abe K, Nakao H, Aiba A, Suzuki H, Kawahara H, Witt C,Ottenheijm C, Labeit S, Ottenheijm C, Granzier H, Toyama-Sorimachi N, Sorimachi M, Sorimachi H
    • Journal Title

      Neuromuscul Disord

      Volume: 20 Pages: 598-599

    • URL

      http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Redundant and non-redundant effects of Ca^<2+> and Na^+ on the activation of p94/calpain-3.2010

    • Author(s)
      Ono, Y.
    • Journal Title

      Neuromuscul.Disord.

      Volume: 20 Pages: 608-608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Redundant and non-redundant effects of Ca^<2+> and Na^+ on the activation of p94/calpain-32010

    • Author(s)
      Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H.
    • Journal Title

      Neuromuscul.Disord.

      Volume: 20 Pages: 608-608

    • Data Source
      KAKENHI-PROJECT-22770139
  • [Journal Article] Expanding members and roles of the calpain superfamily and their genetically modified animals2010

    • Author(s)
      Sorimachi, H., Hata, S., and Ono, Y
    • Journal Title

      Exp. Anim

      Volume: 59 Pages: 549-566

    • NAID

      130000419250

    • URL

      https://www.jstage.jst.go.jp/article/expanim/59/5/59_5_549/_article

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Journal Article] Redundant and non-redundant effects of Ca^<2+> and Na^+ on the activation of p94/calpain-3.2010

    • Author(s)
      Ono Y, Ojima K, Torii F, Takaya E, Doi N, Nakagawa K, Hata S, Abe K, Sorimachi H
    • Journal Title

      Neuromuscul Disord

      Volume: 20 Pages: 608-608

    • URL

      http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy.2010

    • Author(s)
      Ojima K., Kawabata Y., Nakao H., Nakao K., Doi N., Kitamura F., Ono Y., Hata S., Suzuki H., Kawahara H., Bogomolovas J., Witt C., Ottenheijm C., Labeit S., Granzier H., Toyama-Sorimachi N., Sorimachi M., Suzuki K., Maeda T., Abe K., Aiba A., Sorimachi H.
    • Journal Title

      J.Clin.Invest. 120

      Pages: 2672-2683

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] CaMPDB : a Resource for Calpain and Modulatory Proteolysis.2009

    • Author(s)
      duVerle D. A., Takigawa I. Ono Y., Sorimachi H., Mamitsuka H.
    • Journal Title

      Genome Informatics 22

      Pages: 202-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] CaMPDB : a Resource for Calpain and Modulatory Proteolysis.2009

    • Author(s)
      duVerle, D.A., Takigawa, I., Ono, Y., Sorimachi, H., Mamitsuka, H.
    • Journal Title

      Genome Informatics 22

      Pages: 202-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] The importance of conserved amino acid residues in protease sub-domain IIb and the IS2 region in p94 for constitutive autolysis2008

    • Author(s)
      Ono, Y., Hayashi, C., Doi, N., Tagami, M., Sorimachi, H
    • Journal Title

      FEBS Lett 582

      Pages: 691-698

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] カルパインの生理機能とその不全による病態「カルパイノパチー」2008

    • Author(s)
      小野弥子,反町洋之
    • Journal Title

      実験医学 26

      Pages: 306-315

    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Muscle RING-finger protein MuRF1 as a connector of muscle energy metabolism and protein synthesis2008

    • Author(s)
      Koyama, S., Hata, S., Witt, C. C. , Ono, Y., Lerche, S., Ojima, K., Chiba, T., Doi, N., Kitamura, F., Tanaka, K., Abe, K., Witt, S., Rybin, V., Gasch, A., Franz, T., Labeit, S., Sorimachi, H
    • Journal Title

      J. Mol. Biol 376

      Pages: 1224-1236

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] The importance of conserved amino acid residues in protease sub-domain IIb and the IS2 region in p94 for constitutive autolysis2008

    • Author(s)
      Ono, Y., Hayashi, C., Doi, N., Tagami, M., Sorimachi, H.
    • Journal Title

      FEBS Lett. 582

      Pages: 691-698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] The importance of conserved amino acid residues in p94 protease sub-domain IIb and the IS2 refion for constitutive autolysis2008

    • Author(s)
      Ono. Y., Hayaslu, C., Doi, N., Tagami, M., and Sorimachi, H.
    • Journal Title

      FEBS Lett 582

      Pages: 691-698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18770124
  • [Journal Article] Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle.2008

    • Author(s)
      Hayashi C., Ono Y., Doi N., Kitamura F., Tagami M., Mineki R., Arai T., Taguchi H., Yanagida M., Hirner S., Labeit D., Labeit S., Sorimachi H.
    • Journal Title

      J.Biol.Chem. 283

      Pages: 14801-14814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activityin skeletal muscle2008

    • Author(s)
      Hayashi, C., Ono, Y., Doi, N., Kitamura, F., Tagami, M., Mineki, R., Arai, T., Taguchi, H., Yanagida, M., Hirner, S., Labeit, D., Labeit, S., Sorimachi, H
    • Journal Title

      J. Biol. Chem 283

      Pages: 14801-14814

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Muscle RING-Finger Protein(MuRFl)as a Connector of Muscle Energy Metabolism and Protein Synthesis2008

    • Author(s)
      Koyama, S., Hata, S., Witt, C.C., Ono, Y., Lerche, S., Ojima, K., Chiba, T., Doi, N., Kitamura, F., Tanaka, K., Abe, K., Witt, S., Rybin, V., Gasch, A., Franz, T., Labeit, S., and Sorimachi, H.
    • Journal Title

      J.Mol.Biol 376

      Pages: 1224-1236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18770124
  • [Journal Article] Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle2008

    • Author(s)
      Hayashi, C., Ono, Y., Doi, N., Kitamura, F., Tagami, M., Mineki, R., Arai, T., Taguchi, H., Yanagida, M., Hirner, S., Labeit, D., Labeit, S., Sorimachi, H.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 14801-14814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p74/calpain 3 activity in skeletal muscle.2008

    • Author(s)
      Hayashi, C., Ono. Y., Doi, N., Kitamura, E, Tagami, M., Mineki, R., Arai, T., Taguchi, H., Yanagida, M., Hirner, S., Labeit, D., Labeit, S, and Sorimaclu, H
    • Journal Title

      J.Biol.Chem 283

      Pages: 14801-14814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18770124
  • [Journal Article] The importance of conserved amino acid residues in protease sub-domain Iib and the IS2 region in p94 for constitutive autolysis.2008

    • Author(s)
      Ono, Y., Hayashi, C., Doi, N., Tagami, M., and Sorimachi, H.
    • Journal Title

      FEBS Lett. 582

      Pages: 691-698

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis.2008

    • Author(s)
      Koyama S, HataS, Witt CC, Ono Y, Lerche S, Ojima K, Chiba T, Doi N, Kitamura F, Tanaka K, Abe K, Witt SH, Rybin V, Gasch A, Franz T, Labeit S, Sorimachi H
    • Journal Title

      J Mol Biol

      Volume: 376 Issue: 5 Pages: 1224-1236

    • DOI

      10.1016/j.jmb.2007.11.049

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] The importance of conserved amino acid residues in p94 protease sub-domain IIb and the IS2 region for constitutive autolysis.2008

    • Author(s)
      Ono Y, Hayashi C, Doi N, Tagami M, Sorimachi H
    • Journal Title

      FEBS Lett

      Volume: 582 Pages: 691-698

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Muscle RING-finger protein MuRF1 as a connector of muscle energy metabolism and protein synthesis.2008

    • Author(s)
      Koyama S., Hata S., Witt C. C., Ono Y., Lerche S., Ojima K., Chiba T., Doi N., Kitamura F., Tanaka K., Abe K., Witt S., Rybin V., Gasch A., Franz T., Labeit S., Sorimachi H.
    • Journal Title

      J.Mol.Biol. 376

      Pages: 1224-1236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p94/caplain 3 activity in skeletal muscle.2008

    • Author(s)
      Hayashi, C., Ono, Y., Doi, N., Kitamura, F., Tagami, M., Mineki, R., Arai, T., Taguchi, H., Yanagida, M., Hirner, S., Labeit, D., Labeit, S., and Sorimachi, H.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 14801-14814

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] The importance of conserved amino acid residues in protease sub-domain IIb and the IS2 region in p94 for constitutive autolysis.2008

    • Author(s)
      Ono Y., Hayashi C., Doi N., Tagami M., Sorimachi H.
    • Journal Title

      FEBS Lett. 582

      Pages: 691-698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Multiple molecular interactions implicate the connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle.2008

    • Author(s)
      Hayashi C, Ono Y, Doi N, Kitamura F, Tagami M, Mineki R, Arai T, Taguchi H, Yanagida M, Hirner S, Labeit D, Labeit S, Sorimachi H
    • Journal Title

      J Biol Chem

      Volume: 283 Pages: 14801-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Comprehensive survey of p94/calpain 3 substrates by comparative proteomics - Possible regulation of protein synthesis by p942007

    • Author(s)
      Ono, Y., Hayashi, C., Doi, N., Kitamura, F., Shindo, M., Kudo, K., Tsubata, T., Yanagida, M., Sorimachi, H
    • Journal Title

      Biotech. J 2

      Pages: 565-576

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Myogenic stage, sarcomere length, and protease activity modulate localization of muscle-specific calpain.2007

    • Author(s)
      Ojima K, Ono Y, Doi N, Yoshioka K, Kawabata Y, Labeit S, Sorimachi H
    • Journal Title

      J Biol Chem

      Volume: 282 Issue: 19 Pages: 14493-14504

    • DOI

      10.1074/jbc.m610806200

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Comprehensive survey of p94/calpain 3 substrates by comparative proteomics -Possible regulation of protein synthesis by p94.2007

    • Author(s)
      Ono, Y., Hayashi, C., Doi, N., Kitamura, F., Shindo, M., Kudo, K., Tsubata, T., Yanagida, M., Sorimachi, H.
    • Journal Title

      Biotech. J. (in press)

    • Data Source
      KAKENHI-PROJECT-18770124
  • [Journal Article] Myogenic stage, sarcomere length and protease activity modulate localization ofmuscle-specific calpain2007

    • Author(s)
      Ojima, K., Ono, Y., Doi, N., Yoshioka, K., Kawabata, Y., Labeit, S., Sorimachi, H
    • Journal Title

      J. Biol. Chem 282

      Pages: 14493-14504

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Comprehensive survey of p94/calpain 3 substrates by comparative proteomics--possible regulation of protein synthesis by p94.2007

    • Author(s)
      Ono Y, Hayashi C, Doi N, Kitamura F, Shindo M, Kudo K, Tsubata T, Yanagida M, Sorimachi H
    • Journal Title

      Biotech J

      Volume: 2 Issue: 5 Pages: 565-576

    • DOI

      10.1002/biot.200700018

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Suppressed disassembly of autolyzing p94/CAPN3 by N2A connectin/titin in a genetic reporter system.2006

    • Author(s)
      Ono Y, Torii F, Ojima K, Doi N, Yoshioka K, Kawabata Y, Labeit D, LabeitS, Suzuki K, Abe K, Maeda T, Sorimachi H
    • Journal Title

      J Biol Chem

      Volume: 281 Issue: 27 Pages: 18519-31

    • DOI

      10.1074/jbc.m601029200

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] How do defects in proteolytic functions of skeletal muscle-specific calpain, p94/calpain 3, cause calpainopathy/LGMD2A?2006

    • Author(s)
      Sorimachi H, Ojima K, Yanagida M, Ogawa H, Hayashi C, Doi N, Ono Y
    • Journal Title

      Neuromuscul Disord

      Volume: 16

    • URL

      http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description.

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Effect of N2A connectin/titin on disassembly of p94/CAPN3 caused by auaolysis in IS2.2006

    • Author(s)
      Ono Y, Torii F, Ojima K, Doi N, Yoshioka K, Labeit D, Labeit S, Suzuki K, Abe K, Maeda T, Sorimachi H
    • Journal Title

      FEBS Journal

      Volume: 273 Supp1. Issue: s1 Pages: 50-50

    • DOI

      10.1111/j.1742-4658.2006.05276.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Spatio-temporal expression of muscle-specific calpain, p94/calpain 3, during myogenesis.2006

    • Author(s)
      Ojima K, Ono Y, Doi N, Labeit S, Sorimachi H
    • Journal Title

      Neuromuscul Disord

      Volume: 16

    • URL

      http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description.

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] N2A connectin/titin suppressed disassembly of p94/CAPN3 caused by autolysis of IS2 but not IS1 in a genetic reporter system.2006

    • Author(s)
      Ono, Y.et al.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 18519-18531

    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Suppressed disassembly of autolyzing p94/CAPN3 in a genetic reporter system2006

    • Author(s)
      Ono, Y., Torii, F., Ojima, K., Doi, N., Yoshioka, K., Kawabata, Y., Labeit, D., Labeit, S., Suzuki,K., Abe, K., Maeda, T., Sorimachi, H
    • Journal Title

      J. Biol. Chem 281

      Pages: 18519-18531

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Spatio-temporal expression of muscle-specific calpain, p94/calpain 3, during myogenesis.2006

    • Author(s)
      Ojima, K., Ono, Y., Doi, N., Labeit, S., Sorimachi, H.
    • Journal Title

      Neuromuscul. Disord. 16, suppl

      Pages: 56-56

    • Data Source
      KAKENHI-PROJECT-18770124
  • [Journal Article] How do defects in proteolytic functions of skeletal muscle-specific calpain, p94/calpain 3, cause calpainopathy/LGMD2A?2006

    • Author(s)
      Sorimachi, H., Ojima, K., Yanagida, M., Ogawa, H., Hayashi, C., Doi, N., Ono, Y.
    • Journal Title

      Neuromuscul. Disord. 16, suppl.

      Pages: 148-148

    • Data Source
      KAKENHI-PROJECT-18770124
  • [Journal Article] Relationships between p94/CAPN3 and N2A connectin/titin in skeletal muscle under the normal and dystrophic conditions.2006

    • Author(s)
      Ono Y, Ojima K, Doi N, Hayashi C, Torii F, 40K, Labeit D, Labeit S, Suzuki K, Abe K, Maeda T, Sorimachi H
    • Journal Title

      Neuromuscul Disord

      Volume: 16

    • URL

      http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description.

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Relationships between p94/CAPN3 and N2A connectin/titin in skeletal muscle under the normal and dystrophic conditions.2006

    • Author(s)
      Ono, Y., Ojima, K., Doi, N., Hayashi, C., Torii, F., Yoshioka, K., Labeit, D., Labeit, S., Suzuki, K., Abe, K., Maeda, T., Sorimachi, H.
    • Journal Title

      Neuromuscul. Disord. 16, suppl

      Pages: 72-72

    • Data Source
      KAKENHI-PROJECT-18770124
  • [Journal Article] Suppressed disassembly of autolyzing p94/CAPN3 in a genetic reporter system.2006

    • Author(s)
      Ono, Y., Torii, F., Ojima, K., Doi, N., Yoshioka, K., Kawabata, Y., Labeit, D., Labeit, S., Suzuki, K., Abe, K., Maeda, T., Sorimachi, H.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 15219-15231

    • Data Source
      KAKENHI-PROJECT-18770124
  • [Journal Article] Effect of N2A connectin/titin on disassembly of p94/CAPN3 caused by auaolysis in IS2.2006

    • Author(s)
      Ono, Y., Torii, F., Ojima, K., Doi, N., Yoshioka, K., Labeit, D., Labeit, S., Suzuki, K., Abe, K., Maeda, T., Sorimachi, H.
    • Journal Title

      FEBS J. 273, suppl.

      Pages: 50-50

    • Data Source
      KAKENHI-PROJECT-18770124
  • [Journal Article] N2A connectin/titin suppressed disassembly of p94/CAPN3 caused by autolysis of IS2 but not IS1 in a genetic reporter system.2006

    • Author(s)
      Ono, Y.et al.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 18519-18531

    • Data Source
      KAKENHI-PROJECT-17028055
  • [Presentation] nexpected protein products from calpain-10 (CAPN10) cDNA.2019

    • Author(s)
      Ono, Y.
    • Organizer
      FASEB Summer Research Conferences; The Biology of Calpains in Health and Disease Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06236
  • [Presentation] カルパインの特性を規定する基質特異性の定量的構造活性相関解析2017

    • Author(s)
      大内 史子、小山傑、進藤 真由美、馬見塚拓、瀧川一学、尾嶋孝一、秦 勝志、小野 弥子、反町 洋之
    • Organizer
      日本農芸化学会2017年度大会
    • Place of Presentation
      京都女子大学(京都府京都市)
    • Year and Date
      2017-03-19
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] カルパイン3の自己分解と活性化について2017

    • Author(s)
      1.小野弥子,土井奈穂子,反町洋之
    • Organizer
      2017年度日本農芸化学会大会
    • Place of Presentation
      京都女子大学(京都府京都市)
    • Data Source
      KAKENHI-PROJECT-25440059
  • [Presentation] カルパイン3欠損型およびプロテアーゼ活性欠失変異型マウスの比較プロテオミクスによる肢帯型筋ジストロフィー2A型発症機序の解析2016

    • Author(s)
      大内史子、進藤真由美、伊藤義城、小野弥子、秦勝志、今西美知子、反町洋之
    • Organizer
      日本農芸化学会大会
    • Place of Presentation
      札幌コンベンションセンター、北海道札幌市
    • Year and Date
      2016-03-29
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] Quantitative structure-acitivity relationship (QSAR) analysis of calpain substrate specificity---Can we predict cleavage by calpain?2016

    • Author(s)
      Shinkai-Ouchi F, Koyama S, Shindo M, Mamitsuka H, Ono Y, Sorimachi H.
    • Organizer
      FASEB Science Research Conferences, “The biology of Calpains in health and desease”
    • Place of Presentation
      米国 モンタナ州 ビッグスカイ
    • Year and Date
      2016-07-18
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] カルパインの基質部位の予測、第21回 日本病態プロテアーゼ学会2016

    • Author(s)
      2大内史子、小山傑、小野弥子、秦勝志、尾嶋孝一、進藤真由美、duVerle D., 土井奈緖子、瀧川一学、馬見塚拓、反町洋之
    • Organizer
      第21回 日本病態プロテアーゼ学会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2016-08-05
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] Proteomic approach for elucidation of calpains’ substrate specificities2016

    • Author(s)
      Shinkai-Ouchi F, Koyama S, Shindo M, Hata S, Ono Y, Mamitsuka H, Sorimachi H
    • Organizer
      医学研国際シンポジウム
    • Place of Presentation
      公益財団法人東京都医学総合研究所 (東京都世田谷区)
    • Year and Date
      2016-06-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] 肢帯型筋ジストロフィー2A型のモデルとしてのカルパイン3ノックアウトおよびプロテアーゼ活性欠失変異型マウスの比較プロテオーム解析2015

    • Author(s)
      大内史子、進藤真由美、伊藤義城、小野弥子、秦勝志、今西美知子、反町洋之
    • Organizer
      病態プロテアーゼ学会
    • Place of Presentation
      ANAクラウンプラザホテルグランコート名古屋、愛知県名古屋市
    • Year and Date
      2015-08-21
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] カルパインの基質切断部位の特異席解明に向けた網羅的解析2015

    • Author(s)
      大内史子、進藤真由美、小野弥子、秦勝志、反町洋之
    • Organizer
      日本農芸化学会大会
    • Place of Presentation
      岡山大学 岡山市
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] Calpain functions and muscle homeostasis/dystrophies2014

    • Author(s)
      Sorimachi H, Shinkai-Ouchi F, Tonami K, Ojima K, Doi N, Kitamura F, Hata S, Ono Y
    • Organizer
      2014 Yonsei BK21plus-Igakuken joint symposium
    • Place of Presentation
      延正大学、ソウル、大韓民国
    • Year and Date
      2014-06-19
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] カルパイン3ノックアウトマウス(CAPN3-KO)、プロテアーゼ活性欠失変異型マウス(CAPN3-CSKI)の表現型比較とCAPN3の非酵素的機能2014

    • Author(s)
      大内史子、小野弥子、秦勝志、今西美知子、反町洋之
    • Organizer
      病態プロテアーゼ学会
    • Place of Presentation
      千里ライフサイエンスセンター 大阪府豊中市
    • Year and Date
      2014-08-08
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] Similarity and difference of substrate selectivities between two conventional calpains2014

    • Author(s)
      Shinkai-Ouchi F, Shindo M, Hata S, Ono Y, Sorimachi H
    • Organizer
      2014 Yosnei BK21plus-CBSM international joint symposium
    • Place of Presentation
      安東、大韓民国
    • Year and Date
      2014-06-20
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] Muscle homeostasis modulated by calpains.2014

    • Author(s)
      Sorimachi H, Tonami K, Shinkai-Ouchi F, Hata S, Ojima K, Ono Y
    • Organizer
      XIVth Symposium on Proteases, Inhibitors and Biological Control.
    • Place of Presentation
      Portoroz, Slovenia
    • Year and Date
      2014-09-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] カルパイン機能不全と疾患 Calpains in health and disease2013

    • Author(s)
      反町洋之、秦勝志、礪波一夫、大内史子、小野弥子
    • Organizer
      日本薬学会第133回年会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-23247021
  • [Presentation] Identification of phosphorylation sites of muscle-specific calpain-32013

    • Author(s)
      Koichi Ojima, Yasuko Ono, Shoji Hata, Oe Mika, Ikuyo Nakajima, Susumu Muroya, Koichi Chikuni, Hiroyuki Sorimachi
    • Organizer
      FASEB Science Research Conferences, The Biology of Calpains in Health and Disease
    • Place of Presentation
      Saxton River, VT, USA
    • Data Source
      KAKENHI-PROJECT-23500477
  • [Presentation] Effects of phosphorylation of muscle-specific calpain-3 on its proteolytic activity.2013

    • Author(s)
      Koichi Ojima, Yasuko Ono, Shoji Hata, Oe Mika, Ikuyo Nakajima, Susumu Muroya, Koichi Chikuni, Hiroyuki Sorimachi
    • Organizer
      2013 Annual Meeting of the American Society for Cell Biology
    • Place of Presentation
      NewOrleans, LA, USA
    • Data Source
      KAKENHI-PROJECT-23500477
  • [Presentation] カルパイン3のリン酸化が酵素活性に与える影響2013

    • Author(s)
      尾嶋孝一, 小野弥子, 秦勝志, 大江美香, 中島郁世, 千国幸一, 室谷進, 反町洋之
    • Organizer
      日本畜産学会第117回大会
    • Place of Presentation
      新潟市
    • Data Source
      KAKENHI-PROJECT-23500477
  • [Presentation] STRUCTURE-FUNCTION RELATIONSHIP OF Na^+-DEPENDENT ACTIVITY OF MUSCLE-SPECIFIC CALPAIN2012

    • Author(s)
      Ono,Y., Takaya, E., Doi, N., Kitamura, F., Sorimachi, H
    • Organizer
      SPIBC 2012(第13回プロテアーゼおよびその阻害剤と生体制御に関する国際会議)
    • Place of Presentation
      Portoroz, Slovenia
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] 筋特異的カルパインCAPN3/p94活性化機構における分子間相補の解析 (Inter-molecular interaction involved in the activation of CAPN3/p94)2012

    • Author(s)
      小野弥子,田尾あすみ,北村ふじ子,反町洋之
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] 骨格筋特異的に発現するカルパイン3はNa+により活性化する2012

    • Author(s)
      尾嶋孝一, 小野弥子, 中島郁世, 大江美香, 室谷進 , 反町洋之
    • Organizer
      日本畜産学会第115回大会
    • Place of Presentation
      名古屋大学(愛知県)
    • Data Source
      KAKENHI-PROJECT-23500477
  • [Presentation] Towards understanding the enigmatic substrate specificity of calpains2012

    • Author(s)
      Sorimachi, H., duVerle, D., Hata, S., Tonami, K., Ouchi, F., Ojima, K., Takigawa, I., Mamitsuka, H. and Ono, Y.
    • Organizer
      XIIIth Symposium on Proteases, Inhibitors and Biological Control
    • Place of Presentation
      Portoroz, Slovenia
    • Invited
    • Data Source
      KAKENHI-PROJECT-23247021
  • [Presentation] Characterization of sodium-dependent protease activity of muscle-specific calpain2012

    • Author(s)
      Ono,Y., Ouchi, F., Kitamura, F., Sorimachi, H
    • Organizer
      CAPN3. EMC2012(第41回ヨーロッパ筋機能研究学会)
    • Place of Presentation
      Rhodes, Greek
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] 筋特異的カルパインCAPN3/p94の新奇活性化機構の解析2011

    • Author(s)
      小野弥子,田尾あすみ,北村ふじ子,反町洋之
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] Structure-function relationship of Na^+-dependent activity of calpain-3/p942011

    • Author(s)
      Ono, Y
    • Organizer
      Korea-Japan symposium on protein metabolism
    • Place of Presentation
      Seoul National University, Seoul, Korea
    • Year and Date
      2011-01-28
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] Structure-function relationship of Na^+-dependent activity of calpain-3/p942011

    • Author(s)
      Ono, Y.
    • Organizer
      Korea-Japan symposium on protein metabolism
    • Place of Presentation
      ソウル大学(韓国)(招待講演)
    • Year and Date
      2011-01-28
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] Studies of titin signaling and CAPN3.2011

    • Author(s)
      Sorimachi, H., Ojima, K., and Ono, Y.
    • Organizer
      LGMD2A Workshop: Coalition to Cure Calpain 3(C3)
    • Place of Presentation
      Santa Monica, USA.
    • Year and Date
      2011-10-27
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Structure-Function relationship of Na+-dependent activity of calpain-3/p94.2011

    • Author(s)
      小野弥子
    • Organizer
      The 17th Symposium on Ca2+-Binding Proteins and Ca2+ Function in Health and Disease
    • Place of Presentation
      Beijing, China
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] Autolytic activity of skeletal muscle-specific calpain, CAPN3, diversifies its functions?2011

    • Author(s)
      Ono, Y., Doi, N., Kitamura, F., Sorimachi, H
    • Organizer
      CMM, MCB, and CBC joint retreat, Biosphere 2
    • Place of Presentation
      University of Arizona, Tucson, USA
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] Does the severity of the LGMD2A phenotype in compound heterozygotes depend on the combination of mutations?2011

    • Author(s)
      Ono, Y., Saenz, A., Sorimachi, H., Lopez de Munain, A
    • Organizer
      The 7th International Proteolysis Society meeting
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] Functional aspects of unique autolytic activity of CAPN32011

    • Author(s)
      Ono, Y
    • Organizer
      Department of Cellular and Molecular Medicine
    • Place of Presentation
      University of Arizona, Tucson, USA
    • Year and Date
      2011-02-11
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] Unique properties of muscle-specific calpain and muscular dystrophy caused by its defect.2011

    • Author(s)
      Sorimachi, H., Ojima, K., and Ono, Y.
    • Organizer
      IPS2011 - Seventh General Meeting of the International Proteolysis Society
    • Place of Presentation
      San Diego, USA.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Calpain-3/p94のNa依存性について2011

    • Author(s)
      小野弥子
    • Organizer
      平成22年度科学研究費補助金特定領域研究「タンパク質分解による細胞・個体機能の制御」班会議
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] Structural functions of skeletal muscle-specific calpain in Ca2+ efflux from the sarcoplasmic reticulum2011

    • Author(s)
      Koichi Ojima, Yasuko Ono, Coen Ottenheijm, Shoji Hata, Hidenori Suzuki, Mika Oe, Ikuyo Nakajima, Susumu Muroya, Henk Granzier, and Hiroyuki Sorimachi
    • Organizer
      2011 Annual Meeting of the American Society for Cell Biology.
    • Place of Presentation
      Denver, CO. (USA)
    • Data Source
      KAKENHI-PROJECT-23500477
  • [Presentation] Skeletal muscle-specific calpain is an intracellular Ca^<2+> and Na^+-dependent protease.2011

    • Author(s)
      Sorimachi, H., Ojima, K., Takaya, E., and Ono Y.
    • Organizer
      CaBP17 - The 17th International Symposium on Ca^<2+>-binding proteins and Ca^<2+> function in health and disease.
    • Place of Presentation
      Beijing, China.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Structure-Function relationship of Na^+-dependent activity of calpain-3/p942011

    • Author(s)
      Ono, Y., Takaya, E., Doi, N., Kitamura, F., Sorimachi, H
    • Organizer
      The 17th Symposium on Ca^<2+>-Binding Proteins and Ca^<2+> Function in Health and Disease
    • Place of Presentation
      Beijing, China
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] Characteristics of p94/calpain 3 as an intracellular Na^+-dependent protease2010

    • Author(s)
      Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H.
    • Organizer
      FASEB Summer Research Conferences
    • Place of Presentation
      Carefree, AZ(米国)
    • Year and Date
      2010-07-28
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] Unique functions of mammalian unconventional calpains.2010

    • Author(s)
      Sorimachi, H., Hata, S., Ojima, K., Labeit, S., and Ono, Y.
    • Organizer
      FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
    • Place of Presentation
      Arizona, USA.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Functions of calpain-3/p94 indicated by its unique properties2010

    • Author(s)
      Ono, Y.
    • Organizer
      CHUV (Le Centre Hospitalier Universitaire Vaudois) Special Seminar
    • Place of Presentation
      CHUV大学(スイス)(招待講演)
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] Functions of calpain-3/p94 indicated by its unique properties2010

    • Author(s)
      Ono, Y
    • Organizer
      CHUV (Le Centre Hospitalier Universitaire Vaudois) Special Seminar
    • Place of Presentation
      Lausanne, Switzerland
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] Skeletal muscle-specific calpain, p94/calpain-3, dynamically distributes in skeletal muscle cells to adapt to physical stress, defects of which cause muscular dystrophy.2010

    • Author(s)
      Ono Y., Ojima K., Torii F., Takaya E., Doi N., Nakagawa K., Hata S., Abe K., Sorimachi H.
    • Organizer
      15th International Congress of the World Muscle Society
    • Place of Presentation
      Kumamoto, Japan
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Skeletal muscle-specific calpain, p94/calpain-3, is an intracellular Na^+-dependent protease2010

    • Author(s)
      Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H
    • Organizer
      XIIth Symposium on Proteases, Inhibitors and Biological Control
    • Place of Presentation
      Portoroz, Slovenia
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] p94/calpain3自己消化機構の解析, Inter/Intra molecular interaction involved in the autocatalytic proteolysis of p94/calpain 32010

    • Author(s)
      小野弥子,土井奈穂子,高谷恵美,北村ふじ子,反町洋之
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] 鈴木紘一先生追悼講演「CANPからカルパインそしてCAPNへ」2010

    • Author(s)
      小野弥子,秦勝志,川原裕之,前田達哉,反町洋之
    • Organizer
      日本病態プロテアーゼ学会第15回大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-08-20
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Calpains-introduction2010

    • Author(s)
      Ono, Y., Hata, S., and Sorimachi, H.
    • Organizer
      CHUV(Le Centre Hospitalier Universitaire Vaudois) Special Seminar
    • Place of Presentation
      Lausanne, Swizerland.
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] [Selected for oral presentation] Skeletal muscle-specific calpain, p94/calpain-3, dynamically distributes in skeletal muscle cells to adapt to physical stress, defects of which cause muscular dystrophy.2010

    • Author(s)
      Ojima K., Ono Y., Doi N., Kitamura F., Hata S., Kawabata Y., Suzuki K., Maeda T., Abe K., Nakao H., Aiba A., Nakao K., Suzuki H., Kawahara H., Witt C., Labeit S., Ottenheijm, C., Granzier H., Toyama-Sorimachi N., Sorimachi M., Sorimachi H.
    • Organizer
      15th International Congress of the World Muscle Society
    • Place of Presentation
      Kumamoto, Japan
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Characteristics of p94/calpain-3 as an intracellular Na^+-dependent protease2010

    • Author(s)
      Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., and Sorimachi, H
    • Organizer
      FASEB Summer Research Conferences . Biology of the calpains in Health and Disease, Carefree, AZ
    • Place of Presentation
      USA
    • Year and Date
      2010-07-28
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] (Selected for oral presentation) Characteristics of p94/calpain 3 as an intracellular Na^+-dependent protease2010

    • Author(s)
      Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., and Sorimachi, H.
    • Organizer
      FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
    • Place of Presentation
      Arizona, USA.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Calpains-introduction CHUV (Le Centre Hospitalier Universitaire Vaudois) Special Seminar2010

    • Author(s)
      小野弥子, 秦勝志, 反町洋之
    • Place of Presentation
      Lausanne, Swizerland
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Redundant and non-redundant effects of Ca^<2+> and Na^+ on the activation of p94/calpain 32010

    • Author(s)
      Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H
    • Organizer
      The 15th International Congress of the World Muscle Society
    • Place of Presentation
      Kumamoto, Japan
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] Skeletal muscle-specific calpain, p94/calpain-3, is an intracellular Na^+-dependent protease2010

    • Author(s)
      Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H.
    • Organizer
      XIIth Symposium on Proteases, Inhibitors and Biological Control
    • Place of Presentation
      Portoroz(スロベニア)
    • Year and Date
      2010-09-28
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] p94/calpain3自己消化機構の解析2010

    • Author(s)
      小野弥子、土井奈穂子、高谷恵美、北村ふじ子、反町洋之
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] [The closing lecture] Unique functions of mammalian unconventional calpains.2010

    • Author(s)
      Sorimachi H., Hata S., Ojima K., Labeit S., Ono Y.
    • Organizer
      FASEB Summer Research Conferences-The Biology of Calpains in Health & Disease
    • Place of Presentation
      Arizona, USA
    • Year and Date
      2010-07-30
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] The closing lecture]In Memoriam Koichi Suzuki: Calpains in muscles and stomach XIIth Symposium on Proteases2010

    • Author(s)
      Ono, Y., Hata, S., Ojima, K., Tonami, K., Kitamura, F., Ueno, M., Takaya, E., Granzier, H., Labeit, S., and Sorimachi, H.
    • Organizer
      Inhibitors and Biological Control
    • Place of Presentation
      Portoroz, Slovenia.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Calpain3/p94自己消化機構の解析2010

    • Author(s)
      小野弥子, 土井奈穂子, 高谷恵美, 北村ふじ子, 反町洋之
    • Organizer
      BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
    • Place of Presentation
      ポートピアホテル(神戸)
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] [The closing lecture] In Memoriam Koichi Suzuki : Calpains in muscles and stomach2010

    • Author(s)
      Ono Y., Hata S., Ojima K., Tonami K., Kitamura F., Ueno M., Takaya E., Granzier H., Labeit S., Sorimachi H.
    • Organizer
      12^<th> Symposium on Proteases, Inhibitors and Biological Control
    • Place of Presentation
      Portoroz, Slovenia
    • Year and Date
      2010-09-28
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Calpain3/p94自己消化機構の解析2010

    • Author(s)
      小野弥子,土井奈穂子,高谷恵美,北村ふじ子,反町洋之
    • Organizer
      BMB2010 (第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22770139
  • [Presentation] Calpain-3 and molecular interactions.2009

    • Author(s)
      Sorimachi H., Ojima K., Hata S., Ono Y.
    • Organizer
      Calpaines et Calpainopathies. VII^<es> Journees annuelles de la Societe Francaise de Myologie
    • Place of Presentation
      Hendaye, France
    • Year and Date
      2009-10-30
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Calpain-3 and molecular interactions. Calpaines et Calpainopathies.2009

    • Author(s)
      Sorimachi, H., Ojima, K., Hata, S., andOno, Y.
    • Organizer
      VIIes Journees annuelles de la SFM(Societe Francaise de Myologie)
    • Place of Presentation
      Hendaye, France.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] カルパインの多彩な生理機能とその破綻による病態2009

    • Author(s)
      反町洋之,小野弥子,秦勝志,尾嶋孝一
    • Organizer
      第82回日本生化学会大会シンポジウム「プロテオリシスの多彩な生理機能とその破綻による病態」
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] カルパイン及びコネクチンの構造-病態生理相関(Structure-Pathophysiological-Function Relationships of Calpain and Connectin/Titin.)2008

    • Author(s)
      反町洋之、小野弥子、尾嶋孝一、林智佳子、土井奈穂子、北村ふじ子、小山傑、楠畑かおり、秦勝志、Labeit, S.
    • Organizer
      第8回日本蛋白質科学会年会 シンポジウム「蛋白質の輪廻転生-セントラルドグマを超えて」
    • Place of Presentation
      東京
    • Year and Date
      2008-06-12
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Roles of skeletal muscle-specific calpain, p94/calpain 3, on multiple molecular interactions using connectin/titin N2A region as a modulating scaffold2008

    • Author(s)
      Sorimachi, H., Hayashi, C., Hata, S., Ojima, K., Koyama, S., Doi, N., Kitamura, F., Takaya, E., Ueno, M., Kaneko, N., Ono, Y.
    • Organizer
      11th International Symposium on PROTEINASE INHIBITORS AND BIOLOGICAL CONTROL
    • Place of Presentation
      Portoroz, Slovenia
    • Year and Date
      2008-09-02
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Analysis of structure-function relationships of p94 by proteinase-trapping system2008

    • Author(s)
      Ono, Y
    • Organizer
      The Joint 4th AOHUP (Asian Oceania Human Proteome Organisation) and 2nd PRICPS (Pacific Rim International Conference on Protein Science)
    • Place of Presentation
      Cairns, Australia
    • Year and Date
      2008-06-22
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Roles of skeletal muscle-specific calpain, p94/calpain 3, on multiple molecular interactions using connectin/titin N2A region as a modulating scaffold.2008

    • Author(s)
      Sorimachi H., Hayashi C., Hata S., Ojima K., Koyama S., Doi N., Kitamura F., Takaya E., Ueno M., Kaneko N., Ono Y.
    • Organizer
      11^<th> International Symposium on Proteinase Inhibitors and Biological Control
    • Place of Presentation
      Portoroz, Slovenia
    • Year and Date
      2008-09-02
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Roles of skeletal muscle-specific calpain, p94/calpain 3, on multiple molecular interactions using connectin/titin N2A region as a modulating scaffold.2008

    • Author(s)
      Sorimachi, H., Hayashi, C., Hata, S., Ojima, K., Koyama, S., Doi, N., Kitamura, F., Takaya, E., Ueno, M., Kaneko, N., and Ono, Y.
    • Organizer
      11th International Symposium on PROTEINASE INHIBITORS AND BIOLOGICAL CONTROL
    • Place of Presentation
      Portoroz, Slovenia.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Toward Understanding Relationships between Proteolytic Activity of Skeletal Muscle-Specific Calpain and Calpainopathy.2007

    • Author(s)
      Ono, Y., Ojima, K., Hata, S., and Sorimachi, H.
    • Organizer
      2007 Korea-Japan Joint Symposium "Protein Modification and Degradation in Human Diseases"
    • Place of Presentation
      Seoul, South Korea.
    • Year and Date
      2007-09-05
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Unconventional calpains.2007

    • Author(s)
      Ono, Y., Ojima, K., Hayashi, C., Doi, N., Kitamura, F., Koyama, S., Hata, S., Labeit, S., Yanagida, M., Maeda, T., and Sorimachi, H.
    • Organizer
      FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
    • Place of Presentation
      Colorado, USA.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Comprehensive survey of p94/calpain 3 substrates by comparafive proteomics.2007

    • Author(s)
      Ono.Y., Hayasly, C., Doi, N., Kitamura, F., Shindo, M., Kenichi Kudo, Tsubata, T., Yanagida, M., and Sorimachi, H.
    • Organizer
      FASEB Summer Research Conferences-The Biology of Calpainsin Health & Disease
    • Place of Presentation
      Colorado,USA
    • Year and Date
      2007-07-15
    • Data Source
      KAKENHI-PROJECT-18770124
  • [Presentation] Novel approaches for analysis of proteolytic activity of muscle-specific calpain p94/calpain 32007

    • Author(s)
      Ono, Y., Ojima, K., Hayashi, C., Doi, N., Kitamura, F., Koyama, S., Hata, S., Labeit, S., Yanagida, M., Maeda, T., and Sorimachi, H.
    • Organizer
      Xth International Symposium on PROTEINASE INHIBITORS AND BIOLOGICAL CONTROL: From single molecules to degradomics
    • Place of Presentation
      Portoroz, Slovenia.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] How do defects in proteolytic functions of skeletal muscle-specific calpain, p94/calpain 3, cause calpainopathy/LGMD2A?2006

    • Author(s)
      Sorimachi, H., Ojima, K., Yanagida, M., Ogawa, H., Hayashi, C., Doi, N., and Ono, Y.
    • Organizer
      XIth International Congress on Neuromuscular Diseases
    • Place of Presentation
      Istanbul, Turkey.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] A novel genetic assay system for a rapidly autolyzing muscle-specific calpain p94/calpain 32006

    • Author(s)
      Ono, Y., Torii, F., Ojima, K., Doi, N., Yoshioka, K., Kawabata, Y., Labeit, D., Labeit, S., Suzuki, K., Abe, K., Maeda, T., Hata, S., Koyama, S., and Sorimachi, H.
    • Organizer
      5^<th> Internationla Conference on Cysteine Proteinases and Their Inhitbitors: From Structure to Regulation and Biology
    • Place of Presentation
      Portoroz, Slovenia.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Extended concept for calpain “activity” – non-proteolytic functions of unconventional calpains.

    • Author(s)
      Sorimachi, H., Tonami, K., Shinkai-Ouchi, F., Hata, S., Ojima, K., and Ono, Y.
    • Organizer
      FASEB Summer Research Conferences &#8211; Biology of Calpains in Health & Disease
    • Place of Presentation
      Vermont, USA.
    • Year and Date
      2013-07-21 – 2013-07-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-23247021
  • [Presentation] 筋特異的カルパインCAPN3/p94の新奇活性化機構の解析

    • Author(s)
      小野弥子
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22770139
  • []

  • 1.  SORIMACHI Hiroyuki (10211327)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 92 results
  • 2.  HATA Shoji (10392375)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 49 results
  • 3.  OJIMA Koichi (60415544)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 37 results
  • 4.  MATSUOKA Kunie (40291158)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  TONAMI Kazuo (70511393)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  SHINKAI-OUCHI Fumiko (00435710)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 7.  宮崎 拓郎 (80398693)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  佐竹 炎 (20280688)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  松本 英成 (30861132)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  SHINDO Mayumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 11.  ITOH Yoshiki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  柴田 秀樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  牧 正敏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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