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SORIMACHI Hiroyuki  反町 洋之

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Researcher Number 10211327
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Affiliation (Current) 2022: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 分野長
Affiliation (based on the past Project Information) *help 2017: 公益財団法人 東京都医学総合研究所, 生体分子先端研究分野, 分野長
2011 – 2017: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 分野長
2010: 東京都医学研究機構, 東京都臨床医学総合研究所, 参事研究員
2010: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 参事研究員
2009 – 2010: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 参事研究員 … More
2009: 東京都医学研究機構, 東京臨床医学総合研究所, 副参事研究員
2007 – 2008: Tokyo Metropolitan Organization for Medical Research, the Tokyo Metropolitan Institute of Medical Science, 副参事研究員
2005 – 2008: Tokyo Metropolitan Organization for Medical Research, The Tokyo Metropolitan Institute of Medical Science, 東京都臨床医学総合研究所, 副参事研究員
2004: The Tokyo Metropolitan Institute of Medical Science (Rinshoken), Tokyo Metropolitan Organization for Medical Research, Department of Enzymatic Regulation for Cell Functions, Department Head, 東京都臨床医学総合研究所, 副参事研究員
2004: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所・酵素機能制御研究部門, 副参事研究員
2002 – 2003: 東京大学, 大学院・農学生命科学研究科・応用生命科学専攻, 助教授
1998 – 2003: University of Tokyo, Graduate School of Agriculture and Life, Associate Professo, 大学院・農学生命科学研究科, 助教授
2001: University of Tokyo, Graduate School of Agricultural and Life Sciences Department of Applied Biological Chemistry,, 農学生命科学研究科・応用生命化学専攻, 助教授
2001: 東京大学, 農学部・生命科学研究科応用生命科学専攻, 助教授
2000: 東京大学, 農学生命科学研究科, 助教授
1997: 千葉大学, 大学院・農学生命科学研究科, 助教授
1993 – 1997: Institute of Molecular and Cellular Biosciences, The University of Tokyo, Assist, 分子細胞生物学研究所, 助手
1994: 東京大学分子細胞生物学研究所, 助手
1992: 東京大学, 応用微生物研究所, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Structural biochemistry / Food science / Functional biochemistry / Functional biochemistry / 食品科学・栄養科学
Except Principal Investigator
Functional biochemistry / Structural biochemistry / Neuroscience in general / 食品科学・栄養科学 … More / Biological Sciences / 神経内科学 / Applied molecular and cellular biology / Pathological medical chemistry Less
Keywords
Principal Investigator
カルパイン / カルシウム / 骨格筋 / 筋ジストロフィー / コネクチン / 酵素 / プロテオリシス / システインプロテアーゼ / 組織特異的発現 / 胃 … More / 蛋白分解 / タンパク質 / ノックインマウス / 胃腸 / 蛋白質 / メンブレン・トラフィック / calpain / 遺伝子発現 / alternative splicing / 遺伝病 / 筋原線維 / モジュレータプロテアーゼ / プロセシング / ターンオーバー / シグナル伝達 / 自己消化 / COPI / タイチン / EF-ハンド / 立体構造 / C2ドメイン / サイクリンA / スプライスバリアント / DNAマイクロアレイ解析 / モジュレータ・プロテアーゼ / ユビキチンリガーゼ / 細胞内タンパク質分解 / 胃腸疾患 / 基質特異性 / 遺伝子改変マウス / calpastatin / skeletal muscle / calcium / protein turn-over / autolysis / muscular dystrophy / 胃潰瘍 / enzyme / protein / proteolysis / mutant mouse / altemative splicing / Ca^<2+>結合領域 / 筋原繊維 / 血球分化 / プロモーター / 細胞周期 / 血球細胞 / 筋肉 / ジフテリアトキシン / 表層粘液細胞 / 内膜輸送系 / 質量分析 / 酵素学 / カルパスタチン / 選択的スプライシング / タンパク質の寿命 / 骨格節 / 節ジストロフィー / モジュレータプロタアーゼ / β-COP / 腸 / stomach / membrane trafficking / COPI小胞 / 食品 / 粘膜 / digestive tract / membrane traffiching / 生体分子 / プロテオーム / 構造機能相関 / 組織特異性 / ドメイン構造 / 細胞内プロテオリシス … More
Except Principal Investigator
カルパイン / プロテアーゼ / 筋ジストロフィー / アルツハイマー病 / 転写因子 / カルパスタチン / プロテインキナーゼC / 情報伝達 / カルシウム / ジストロフィン / 味覚 / 蛋白質分解 / calcium / アミロイド / 分泌 / Alzheimer's disease / Amyloid / Secretion / 筋ジストロフィー症 / Protease / フォドリン / p94 / calpain / fodrin / 活性化機構 / GFP / ブロテアーゼ / カテプシン / アミロイドタンパク質 / アミロイド前駆体 / ジストロフィン類似蛋白質 / 遺伝子発現 / 脳細胞 / アミロイド蛋白質 / プロラクチン / ダウンレギュレーション / トリプレット・リピート / アポトーシス / 筋緊張性ジストロフィー / イオンチャンネル / 筋小胞体 / 培養細胞 / 甘味修飾タンパク質 / 二次元電気泳動 / クルクリン / タンパク質分解 / ユビキチン / オートファジー / プロテオリシス / 細胞内情報伝達 / 細胞構造・機能 / 構造生物学 / 治療 / Dystrophy / Dystrophin / treatment / カルシユム / caplapin / proteases / proteolysis / C-キナーゼ / アミロイドβ蛋白質 / Signal transduction / C kinase / タンパク分解 / 寿命 / PEOTEIN DEGRADATION / CALCIUM / HALF-LIFE / MUSCULAR DYSTROPHY / プロセシング / ソーティング / Signal molecules / Processing / コネクチン / タイチン / カルバイン / 筋肉 / connectin / muscular dystrophy / titin / protease / X線構造解析 / 蛋白質の高次構造 / タンパク質の高次構造 / 蛋白質の構造変化 / リン脂質 / Calpain / Calcium / X ray structural analysis / Higher order structure of protein / Activation mechanism / Phopsholipids / 味蕾細胞 / 初代培養 / Caイオン / 遺伝子導入 / 細胞接着 / 基底膜 / ラミニン / インテグリン / taste bud cell / primary culture / Ca ion / gene introduction / cell adhesion / basement membrane / laminin / integrin / 細胞骨格 / タリン / モジュレータプロテアーゼ / ドメイン / talin / calpastatin / cyteskeltal protein / modulator protease / 肢帯型筋ジストロフィー2A型 / カルパイン-3 / 骨格筋 / 筋成熟遅滞 / カルパイン3 / 筋線維型 / 骨格筋の分化成熟 / 肢帯型筋ジストロフィー / カルパイン3 / プロテオミクス / プロテオーム解析 / 肢帯型筋ジストロフィー2A / ノックアウトマウス Less
  • Research Projects

    (38 results)
  • Research Products

    (230 results)
  • Co-Researchers

    (55 People)
  •  A new biology of calpainPrincipal Investigator

    • Principal Investigator
      反町 洋之
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Elucidation of molecular mechanism of limb-girdle muscular dystrophy through comparative analysis of calpain-3 mutant mice

    • Principal Investigator
      SHINKAI-OUCHI Fumiko
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Tissue-specific functional studies on calpainsPrincipal Investigator

    • Principal Investigator
      SORIMACHI Hiroyuki
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Novel functions of evolutionarily conserved calpain-7/PalBH in membrane trafficking system.Principal Investigator

    • Principal Investigator
      SORIMACHI Hiroyuki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  胃カルパインの粘膜特異的発現を応用した粘液分泌機構解析と食品の粘膜保護機能検索Principal Investigator

    • Principal Investigator
      反町 洋之
    • Project Period (FY)
      2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Food science
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Biomodulation by calpainPrincipal Investigator

    • Principal Investigator
      SORIMACHI Hiroyuki
    • Project Period (FY)
      2006 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      財団法人東京都医学研究機構
      Tokyo Metropolitan Organization for Medical Research
  •  Proteolysis in the Regulation of Biological Processes

    • Principal Investigator
      MIZUSHIMA Noboru
    • Project Period (FY)
      2006 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Functional analysis of digestive tract-specific calpains in terms of functional foods.Principal Investigator

    • Principal Investigator
      SORIMACHI Hiroyuki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Food science
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  カルパインによる筋細胞監視システムとその破綻による筋ジストロフィーPrincipal Investigator

    • Principal Investigator
      反町 洋之
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  カルパインp94の新規バリアントによる細胞周期制御Principal Investigator

    • Principal Investigator
      反町 洋之
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Functional analysis of stomach-specific calpain.Principal Investigator

    • Principal Investigator
      SORIMACHI Hiroyuki
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Food science
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
      The University of Tokyo
  •  カルパインによる細胞周期制御Principal Investigator

    • Principal Investigator
      反町 洋之
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  新しい甘味修飾タンパク質の活性構造相関の解析と物質生産

    • Principal Investigator
      ABE Keiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      食品科学・栄養科学
    • Research Institution
      The University of Tokyo
  •  Studies on mechanisms of calpain activation in the cell

    • Principal Investigator
      INOMATA Mitsushi, 鈴木 紘一
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Institute of Gerontology
  •  カルパイン-コネクチンを介した筋原繊維情報伝達系の解析Principal Investigator

    • Principal Investigator
      反町 洋之
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Establishing a primary taste-cell culture system as a basic analysis for new taste engineering

    • Principal Investigator
      ABE Keiko
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied molecular and cellular biology
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  Research on molecular mechanisms of muscle protein turn-over by structure-function relationship studies of calpainPrincipal Investigator

    • Principal Investigator
      SORIMACHI Hiroyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      食品科学・栄養科学
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  Analysis of Activation Mechanism of Calpain on the Basis of its Tertiary Structure

    • Principal Investigator
      SUZUKI Koichi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      Tokyo Metropolitan Institute of Gerontology
  •  Analysis of a protein turnover system using muscle as a model organ.Principal Investigator

    • Principal Investigator
      SORIMACHI Hiroyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      食品科学・栄養科学
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  筋特異的カルパイン欠損型筋ジストロフィー症の分子機構の解明Principal Investigator

    • Principal Investigator
      反町 洋之
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      The University of Tokyo
  •  Analysis of molecular mechanism of muscular dystrophy involving skeletal muscle-specific calpain and connectin

    • Principal Investigator
      SUZUKI Koichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Functional biochemistry
    • Research Institution
      Institute of Molecular and Cellular Biosciences, University of Tokyo
  •  トリプレット・リピート伸長cDNA発現細胞とアポトーシス

    • Principal Investigator
      石浦 章一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  骨格筋特異的カルパインと筋弾性蛋白質の相互作用の生理的意義Principal Investigator

    • Principal Investigator
      反町 洋之
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      The University of Tokyo
  •  Isolation of signal molecules on the secretion of amyloid precursor

    • Principal Investigator
      ISHIURA Shoichi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neuroscience in general
    • Research Institution
      The University of Tokyo
  •  脳細胞選択死のモデルとしての異常cDNA発現細胞の解析

    • Principal Investigator
      鈴木 絋一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  情報伝達におけるプロテインキナーゼCの消失の意義と機構の解析

    • Principal Investigator
      鈴木 紘一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  組織特異的カルパインと相互作用する分子の検索による機能解析Principal Investigator

    • Principal Investigator
      反町 洋之
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo
  •  Determination and regulation of half-life of the proteins

    • Principal Investigator
      SUZUKI Koichi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      University of Tokyo
  •  転写因子の代謝と転写調節

    • Principal Investigator
      鈴木 鉱一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  組織特異的カルパインの検索・分析によるカルパインファミリーの機能解析Principal Investigator

    • Principal Investigator
      反町 洋之
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo
  •  Secretion of amyloid precursor protein via signal transduction pathway

    • Principal Investigator
      ISHIURA Shoichi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Neuroscience in general
    • Research Institution
      The University of Tokyo
  •  転写因子の代謝と転写調節

    • Principal Investigator
      鈴木 紘一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  ジストロフィンの欠損を補う胎児型アイソフォームの発現調節

    • Principal Investigator
      鈴木 紘一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  平滑筋特異的に発現する新しいカルパイン分子種の構造と機能に関する研究Principal Investigator

    • Principal Investigator
      反町 洋之
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo
  •  Structure and physiological function of novel calpain species

    • Principal Investigator
      SUZUKI Koichi
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      University of Tokyo
  •  転写因子の代謝と転写制御

    • Principal Investigator
      SUZUKI Koichi
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  アミロイド前駆体セクレターゼの同定,発現と制御

    • Principal Investigator
      鈴木 紘一
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Role of dystrophin-related protein in the pathogenesis of Duchenne muscular dystrophy.

    • Principal Investigator
      ISHIURA Shoichi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      神経内科学
    • Research Institution
      Institute of Molecular and Cellular Biosciences, The University of Tokyo

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book Patent

  • [Book] Encyclopedia of Biological Chemistry, Vol.1, A-D2004

    • Author(s)
      Sorimachi, H.
    • Total Pages
      827
    • Publisher
      Elsevier, Oxford (eds., W.J. Lennarz and M.D. Lane)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Elucidation of the molecular mechanism of disease development due to calpain dysfunction ? CALPAIN2018

    • Author(s)
      Sorimachi H, Ono Y, Hata S, Shimakai-Ouchi F
    • Journal Title

      Impact

      Volume: 2018 Pages: 74-76

    • DOI

      10.21820/23987073.2018.2.74

    • Open Access
    • Data Source
      KAKENHI-PROJECT-26450172, KAKENHI-PROJECT-26670166
  • [Journal Article] Predictions of cleavability of calpain proteolysis by quantitative structure-activity relationship analysis using newly determined cleavage sites and catalytic efficiencies of an oligopeptide array.2016

    • Author(s)
      Shinkai-Ouchi F, Koyama S, Ono Y, Hata S, Ojima K, Shindo M, duVerle D, Ueno M, Kitamura F, Doi N, Takigawa I, Mamitsuka H, Sorimachi H.
    • Journal Title

      Molecular and Cellular Proteomics

      Volume: 15 Pages: 1262-1280

    • DOI

      10.1074/mcp.m115.053413

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25440059, KAKENHI-PROJECT-26450172, KAKENHI-PROJECT-26670166, KAKENHI-PROJECT-15H02389
  • [Journal Article] Calpain research for drug discovery: Challenges and potential.2016

    • Author(s)
      Ono Y, Saido TC, Sorimachi H
    • Journal Title

      Nature Reviews Drug Discovery

      Volume: 15 Pages: 854-876

    • DOI

      10.1038/nrd.2016.212

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H02389, KAKENHI-PROJECT-25440059
  • [Journal Article] Disturbance of pre-mRNA splicing by calpain-6 aggravates pinocytotic cholesterol deposition in macrophages.2016

    • Author(s)
      Miyazaki T, Tonami K, Hata S, Aiuchi T, Ohnishi K, Lei XF, Kim-Kaneyama JR, Takeya M, Itabe H, Sorimachi H, Kurihara H, Miyazaki A
    • Journal Title

      J. Clin. Invest.

      Volume: 126 Pages: 3417-32

    • DOI

      10.1172/jci85880

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02389, KAKENHI-PROJECT-26460454, KAKENHI-PROJECT-26461149, KAKENHI-PROJECT-26461368, KAKENHI-PROJECT-15K21367, KAKENHI-PROJECT-26860588, KAKENHI-PROJECT-15K07944, KAKENHI-PROJECT-15K09418, KAKENHI-PROJECT-16K10553, KAKENHI-PROJECT-26450172, KAKENHI-PROJECT-15H02536
  • [Journal Article] An eccentric calpain, CAPN3/p94/calpain-3.2016

    • Author(s)
      Ono, Y., Ojima, K., Shinkai-Ouchi, F., Hata, S., and Sorimachi, H.
    • Journal Title

      Biochimie

      Volume: 122 Pages: 169-187

    • DOI

      10.1016/j.biochi.2015.09.010

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25440059, KAKENHI-PROJECT-26670166, KAKENHI-PROJECT-15H02389, KAKENHI-PROJECT-26450172
  • [Journal Article] A gastrointestinal calpain complex, G-calpain, is a heterodimer of CAPN8 and CAPN9, which play catalytic and regulatory roles, respectively.2016

    • Author(s)
      Hata S, Kitamura F, Yamaguchi M, Shitara H, Murakami M, Sorimachi H
    • Journal Title

      Journal of Biological Chemistry

      Volume: 291 Pages: 27313-27322

    • DOI

      10.1074/jbc.m116.763912

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02389, KAKENHI-PROJECT-26450172
  • [Journal Article] The N- and C-terminal autolytic fragments of CAPN3/p94/calpain-3 restore proteolytic activity by intermolecular complementation.2014

    • Author(s)
      Ono, Y., Shindo, M., Doi, N., Kitamura, F., Gregorio, C. C., and Sorimachi, H.
    • Journal Title

      Proc. Natl. Acad. Sci. U. S. A.

      Volume: 111

    • DOI

      10.1073/pnas.1411959111

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23247021
  • [Journal Article] Calpain-6 deficiency promotes skeletal muscle development and regeneration.2013

    • Author(s)
      Tonami, K., Hata, S., Ojima, K., Ono, Y., Kurihara, Y., Amano, T., Sato, T., Kawamura, Y., Kurihara, H., Sorimachi, H.
    • Journal Title

      PLoS Genetics

      Volume: 9 Pages: 1003668-1003668

    • DOI

      10.1371/journal.pgen.1003668

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-11J02638, KAKENHI-PROJECT-23247021, KAKENHI-PROJECT-23590326, KAKENHI-PROJECT-23780152, KAKENHI-PUBLICLY-24115705, KAKENHI-PROJECT-24249047
  • [Journal Article] Understanding the substrate specificity of conventional calpains2012

    • Author(s)
      Sorimachi, H., Mamitsuka, H., Ono, Y
    • Journal Title

      Biological Chemistry

      Volume: 393 Pages: 853-871

    • DOI

      10.1515/hsz-2012-0143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
  • [Journal Article] Calpains - an elaborate proteolytic system2012

    • Author(s)
      Ono Y, Sorimachi H
    • Journal Title

      Biochimica et Biophysica Acta

      Volume: 1824 Pages: 224-236

    • DOI

      10.1016/j.bbapap.2011.08.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
  • [Journal Article] Functional evolution of duplicated odorant-binding protein genes, Obp57d and Obp57e, in Drosophila.2012

    • Author(s)
      Eriko Harada
    • Journal Title

      PLoS One

      Volume: 7(1)

    • DOI

      10.1371/journal.pone.0029710

    • NAID

      120004738514

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J06539, KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-21688003
  • [Journal Article] Regulation and physiological roles of the calpain system in muscular disorders2012

    • Author(s)
      Sorimachi, H., Ono, Y
    • Journal Title

      Cardiovascular Research

      Volume: 96 Pages: 11-22

    • DOI

      10.1093/cvr/cvs157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
  • [Journal Article] High efficient expression and purification of recombinant human m-calpain using Escherichia coli expression system at low temperature.2012

    • Author(s)
      Hata S, Ueno M, Kitamura F, Sorimachi H
    • Journal Title

      J. Biochem.

      Volume: 151 Pages: 417-422

    • DOI

      10.1093/jb/mvs002

    • NAID

      10031166080

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-23780152
  • [Journal Article] Calpain2012

    • Author(s)
      Sorimachi H
    • Journal Title

      Encyclopedia of Biological Chemistry 2nd Edition(Lane MD, Lennarz WJ, eds., Oxford, UK: Elsevier Academic Press)

      Volume: in press

    • URL

      http://store.elsevier.com/product.jsp?isbn=9780080547756&pagename=search

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Chapter 453-6 and 458. μ-calpain, m-calpain, Muscle calpain, Gastrointestinal calpain, and other calpains.2012

    • Author(s)
      Sorimachi H, Ono Y, Hata S
    • Journal Title

      Handbook of Proteolytic enzymes, 3rd Edition(Rawlings ND, Salvesen G, eds)(Oxford, UK: Elsevier Academic Press.)

      Volume: in press

    • URL

      http://store.elsevier.com/product.jsp?Isbn=9780123822192&pagename=search

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Does the severity of the LGMD2A phenotype in compound heterozygotes depend on the combination of mutations?2011

    • Author(s)
      Saenz A., Ono Y., Sorimachi H., Goicoechea M., Leturcq F., Blazquez L., Garcia-Bragado F., Marina A., Poza J.J., Azpitarte M., Doi N., Urtasun M., Kaplan J.C., Lopez de Munain A.
    • Journal Title

      Muscle Nerve (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Impact of genetic insights into calpain biology.2011

    • Author(s)
      Sorimachi, H.
    • Journal Title

      Journal of Biochemistry

      Volume: 150 Pages: 23-37

    • DOI

      10.1016/b978-0-12-382219-2.00458-0

    • NAID

      10030586192

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23247021
  • [Journal Article] 肢帯型筋ジストロフィーの発症機構2011

    • Author(s)
      反町洋之、小野弥子
    • Journal Title

      生体の科学 62(in press)

    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Calpain-6, a microtubule-stabilizing protein, regulates Racl activity and cell motility through interaction with GEF-Hl.2011

    • Author(s)
      Kazuo Tonami
    • Journal Title

      J Cell Sci

      Volume: 124巻 Pages: 1214-1223

    • DOI

      10.1242/jcs.072561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J02638, KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-23591099
  • [Journal Article] Calpain cleavage prediction using multiple kernel learning.2011

    • Author(s)
      duVerle D. A., Ono Y., Sorimachi H., Mamitsuka H.
    • Journal Title

      PLoS One (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Calpain cleavage prediction using multiple kernel learning2011

    • Author(s)
      duVerle DA, Ono Y, Sorimachi H, Mamitsuka H
    • Journal Title

      PLoS One

      Volume: 6

    • DOI

      10.1371/journal.pone.0019035

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139
  • [Journal Article] 胃粘膜防御に果たすカルパインの役割2011

    • Author(s)
      秦勝志、反町洋之
    • Journal Title

      日本臨床 69(in press)

    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Calpain chronicle-an enzyme family under multidisciplinary characterization.2011

    • Author(s)
      反町洋之, 秦勝志, 小野弥子
    • Journal Title

      Proc.Jpn.Acad.Ser.B 87(in press)

    • NAID

      130000903736

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Calpain 6, a microtubule-stabilizing protein, regulates Rac1 activity and cell motility through interaction with GEF-H1.2011

    • Author(s)
      Tonami K., Kurihara Y., Arima S., Nishiyama K., Uchijima Y., Asano T., Sorimachi H., Kurihara H.
    • Journal Title

      J.Cell Sci. 124(in press)

      Pages: 2011-2011

    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Does the severity of the LGMD2A phenotype in compound heterozygotes depend on the combination of mutations?2011

    • Author(s)
      Saenz A, Ono Y, Sorimachi H, Goicoechea M, Leturcq F, Blazquez L, Garcia-Bragado F, Marina A, Poza JJ, Azpitarte M, Doi N, Urtasun M, Kaplan JC, Lopez de Munain A
    • Journal Title

      Muscle Nerve

      Volume: 44 Pages: 710-714

    • DOI

      10.1002/mus.22194

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
  • [Journal Article] 骨格筋特異的カルパイン-3の活性制御因子は細胞内Na^+~例外か多様性か2011

    • Author(s)
      小野弥子,反町洋之
    • Journal Title

      化学と生物 49

      Pages: 229-231

    • NAID

      10028117186

    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Calpain chronicle--an enzyme family under multidisciplinary characterization.2011

    • Author(s)
      Sorimachi H, HataS, Ono Y
    • Journal Title

      Proc Jpn Acad Ser B Phys Biol Sci

      Volume: 87 Pages: 287-327

    • NAID

      130000903736

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Impact of genetic insights into calpain biology.2011

    • Author(s)
      Sorimachi H, Hata S, Ono Y
    • Journal Title

      J. Biochem

      Volume: 150 Pages: 23-37

    • DOI

      10.1093/jb/mvr070

    • NAID

      10030586192

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139
  • [Journal Article] Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles.2011

    • Author(s)
      Ojima K., Ono Y., Ottenheijm C., Hata S., Suzuki H., Granzier H., Sorimachi H.
    • Journal Title

      J.Mol.Biol. 407

      Pages: 439-449

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Calpain chronicle-an enzyme family under multidisciplinary characterization.2011

    • Author(s)
      Sorimachi, H
    • Journal Title

      Proc.Jpn.Acad.Ser.B

      Volume: 87(in press)

    • NAID

      130000903736

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-18076008
  • [Journal Article] Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles2011

    • Author(s)
      Ojima K, Ono Y, Ottenheijm C, HataS, Suzuki H, Granzier H, Sorimachi H
    • Journal Title

      Journal of Molecular Biology

      Volume: 407 Pages: 439-449

    • DOI

      10.1016/j.jmb.2011.01.057

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
  • [Journal Article] カルパインの組織機能論2011

    • Author(s)
      反町洋之、秦勝志、小野弥子
    • Journal Title

      実験医学 29(in press)

    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Calpain chronicle--an enzyme family under multidisciplinary characterization.2011

    • Author(s)
      Sorimachi, H.
    • Journal Title

      Proc Jpn Acad Ser B Phys Biol Sci

      Volume: 87 Pages: 287-327

    • NAID

      130000903736

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23247021
  • [Journal Article] Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense.2010

    • Author(s)
      Hata S, Abe M, Suzuki H, Kitamura F, Toyama-Sorimachi N, Abe K, Sakimura K, Sorimachi H
    • Journal Title

      PLoS Genet

      Volume: 6

    • DOI

      10.1371/journal.pgen.1001040

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Skeletal muscle-specific calpain is an intracellular Na+-dependent protease.2010

    • Author(s)
      Ono Y., Ojima K., Torii F., Takaya E., Doi N., Nakagawa K., Hata S., Abe K., Sorimachi H.
    • Journal Title

      J.Biol.Chem. 285

      Pages: 22986-22998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Calpain 8/nCL-2 and Calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense.2010

    • Author(s)
      Hata S., Abe M., Suzuki H., Kitamura F., Toyama-Sorimachi N., Abe K., Sakimura K., Sorimachi H.
    • Journal Title

      PLoS Genet.(PLoS Genet. Featured Research選出;SciBX 3(31); doi:10.1038/scibx.2010.956で紹介された) 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy2010

    • Author(s)
      Ojima K, Kawabata Y, Nakao H, Nakao K, Doi N, Kitamura F, Ono Y, HataS, Suzuki H, Kawahara H, Bogomolovas J,Will C, Ottenheijm C, LabeitS, Granzier H, Toyama-Sorimachi N, Sorimachi M, Suzuki K, Maeda T, Abe K, Aiba A, Sorimachi H
    • Journal Title

      J. Clin. Invest

      Volume: 120 Pages: 2672-2683

    • DOI

      10.1172/jci40658

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22300106, KAKENHI-PROJECT-22770139
  • [Journal Article] Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy2010

    • Author(s)
      Ojima, K., Kawabata, Y., Nakao, H., Nakao, K., Doi, N., Kitamura, F., Ono, Y., Hata, S., Suzuki, H., Kawahara, H., Bogomolovas, J., Witt, C., Ottenheijm, C., Labeit, S., Granzier, H., Toyama-Sorimachi, N., Sorimachi, M., Suzuki, K., Maeda, T., Abe, K., Aiba, A., Sorimachi, H.
    • Journal Title

      J.Clin.Invest.

      Volume: 120 Pages: 2672-2683

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Une contribution a l'histoire de la decouverte des calpainopathies.(in French).2010

    • Author(s)
      Fardeau M, Beckmann JS, Sorimachi H, Urtizberea JA
    • Journal Title

      Les Cahiers de Myologie

      Volume: 2 Pages: 5-10

    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Expanding members and roles of the calpain superfamily and their genetically modified animals.2010

    • Author(s)
      Sorimachi H, Hata S, Ono Y
    • Journal Title

      Exp Anim

      Volume: 59 Pages: 549-566

    • NAID

      130000419250

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21030783

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Skeletal muscle-specific calpain is an intracellular Na^+-dependent protease2010

    • Author(s)
      Ono Y, Ojima K, Torii F, Takaya E, Doi N, Nakagawa K, Hata S, Abe K, Sorimachi H
    • Journal Title

      J. Biol. Chem

      Volume: 285 Pages: 22986-22998

    • DOI

      10.1074/jbc.m110.126946

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139
  • [Journal Article] CaMPDB: a resource for calpain and modulatory proteolysis.2010

    • Author(s)
      duVerle DA, Takigawa I, Ono Y, Sorimachi H, Mamitsuka H
    • Journal Title

      Genome Inform

      Volume: 22 Pages: 202-213

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Expanding members and roles of the calpain superfamily and their genetically modified animals.2010

    • Author(s)
      反町洋之, 秦勝志, 小野弥子
    • Journal Title

      Exp.Anim. 59

      Pages: 549-566

    • NAID

      130000419250

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Skeletal muscle-specific calpain is an intracellular Na^+-dependent protease2010

    • Author(s)
      Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H.
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 22986-22998

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Skeletal muscle-specific calpain, p94/calpain-3, dynamically distributes in skeletal muscle cells to adapt to physical stress, defects of which cause muscular dystrophy.2010

    • Author(s)
      Ojima K, Ono Y, Doi N, Kitamura F, Kawabata Y, Suzuki K, Maeda T, Abe K, Nakao H, Aiba A, Suzuki H, Kawahara H, Witt C,Ottenheijm C, Labeit S, Ottenheijm C, Granzier H, Toyama-Sorimachi N, Sorimachi M, Sorimachi H
    • Journal Title

      Neuromuscul Disord

      Volume: 20 Pages: 598-599

    • URL

      http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Une contribution a l'histoire de la decouverte des calpainopathies.2010

    • Author(s)
      Fardeau M., Beckmann J.S., Sorimachi H., Urtizberea J.A.
    • Journal Title

      Les Cahiers de Myologie 2

      Pages: 5-10

    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Expanding members and roles of the calpain superfamily and their genetically modified animals2010

    • Author(s)
      Sorimachi, H
    • Journal Title

      Exp.Anim.

      Volume: 59 Pages: 549-566

    • NAID

      130000419250

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-18076008
  • [Journal Article] Calpain 8/nCL-2 and Calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense2010

    • Author(s)
      Hata, S., Abe, M., Suzuki, H., Kitamura, F., Toyama-Sorimachi, N., Abe, K., Sakimura, K., Sorimachi, H.
    • Journal Title

      PLoS Genet.

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Redundant and non-redundant effects of Ca^<2+> and Na^+ on the activation of p94/calpain-3.2010

    • Author(s)
      Ono Y, Ojima K, Torii F, Takaya E, Doi N, Nakagawa K, Hata S, Abe K, Sorimachi H
    • Journal Title

      Neuromuscul Disord

      Volume: 20 Pages: 608-608

    • URL

      http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy.2010

    • Author(s)
      Ojima K., Kawabata Y., Nakao H., Nakao K., Doi N., Kitamura F., Ono Y., Hata S., Suzuki H., Kawahara H., Bogomolovas J., Witt C., Ottenheijm C., Labeit S., Granzier H., Toyama-Sorimachi N., Sorimachi M., Suzuki K., Maeda T., Abe K., Aiba A., Sorimachi H.
    • Journal Title

      J.Clin.Invest. 120

      Pages: 2672-2683

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Inhibition of calpain increases LIS1 expression and partially rescues in vivo phenotypes in a mouse model of lissencephaly2009

    • Author(s)
      Yamada M, Yoshida Y, Mori D, Takitoh T, Kengaku M, Umeshima H, Takao K, Miyakawa T, Sato M, Sorimachi H, Wynshaw-Boris A, Hirotsune S
    • Journal Title

      Nat. Med

      Volume: 15 Pages: 1202-1207

    • DOI

      10.1038/nm.2023

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-21300121, KAKENHI-PROJECT-21390052
  • [Journal Article] CaMPDB : a Resource for Calpain and Modulatory Proteolysis.2009

    • Author(s)
      duVerle D. A., Takigawa I. Ono Y., Sorimachi H., Mamitsuka H.
    • Journal Title

      Genome Informatics 22

      Pages: 202-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] CaMPDB : a Resource for Calpain and Modulatory Proteolysis.2009

    • Author(s)
      duVerle, D.A., Takigawa, I., Ono, Y., Sorimachi, H., Mamitsuka, H.
    • Journal Title

      Genome Informatics 22

      Pages: 202-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Inhibition of calpain increases LIS1(PAFAH1B1) and partially rescues in vivo phenotypes in a mouse model of lissencephaly.2009

    • Author(s)
      Yamada M., Yoshida Y., Mori D., Takitoh T., Kengaku M., Umeshima H., Takao K., Miyakawa T., Sato M., Sorimachi H., Wynshaw-Boris A., Hirotsune S.
    • Journal Title

      Nature Med. 15

      Pages: 1202-1207

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Inhibition of calpain increases LIS1(PAFAH1B1) and partially rescues in vivo phenotypes in a mouse model of lissencephaly.2009

    • Author(s)
      Yamada, M., Yoshida, Y., Mori, D., Takitoh, T., Kengaku, M., Umeshima, H., Takao, K., Miyakawa, T., Sato, M., Sorimachi, H., Wynshaw-Boris, A., Hirotsune, S.
    • Journal Title

      Nat.Med. 15

      Pages: 1202-1207

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] The importance of conserved amino acid residues in protease sub-domain IIb and the IS2 region in p94 for constitutive autolysis2008

    • Author(s)
      Ono, Y., Hayashi, C., Doi, N., Tagami, M., Sorimachi, H
    • Journal Title

      FEBS Lett 582

      Pages: 691-698

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] カルパインの生理機能とその不全による病態「カルパイノパチー」2008

    • Author(s)
      小野弥子,反町洋之
    • Journal Title

      実験医学 26

      Pages: 306-315

    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Single-cell chemical lysis method for analyses of intracellular molecules using an array of picoliter-scale microwells.2008

    • Author(s)
      Sasuga Y, Iwasawa T, Terada K, Oe Y, Sorimachi H, Ohara O, Harada Y
    • Journal Title

      Anal Chem

      Volume: 80 Pages: 9141-9149

    • DOI

      10.1021/ac8016423

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Muscle RING-finger protein MuRF1 as a connector of muscle energy metabolism and protein synthesis2008

    • Author(s)
      Koyama, S., Hata, S., Witt, C. C. , Ono, Y., Lerche, S., Ojima, K., Chiba, T., Doi, N., Kitamura, F., Tanaka, K., Abe, K., Witt, S., Rybin, V., Gasch, A., Franz, T., Labeit, S., Sorimachi, H
    • Journal Title

      J. Mol. Biol 376

      Pages: 1224-1236

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] The importance of conserved amino acid residues in protease sub-domain IIb and the IS2 region in p94 for constitutive autolysis2008

    • Author(s)
      Ono, Y., Hayashi, C., Doi, N., Tagami, M., Sorimachi, H.
    • Journal Title

      FEBS Lett. 582

      Pages: 691-698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle.2008

    • Author(s)
      Hayashi C., Ono Y., Doi N., Kitamura F., Tagami M., Mineki R., Arai T., Taguchi H., Yanagida M., Hirner S., Labeit D., Labeit S., Sorimachi H.
    • Journal Title

      J.Biol.Chem. 283

      Pages: 14801-14814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activityin skeletal muscle2008

    • Author(s)
      Hayashi, C., Ono, Y., Doi, N., Kitamura, F., Tagami, M., Mineki, R., Arai, T., Taguchi, H., Yanagida, M., Hirner, S., Labeit, D., Labeit, S., Sorimachi, H
    • Journal Title

      J. Biol. Chem 283

      Pages: 14801-14814

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle2008

    • Author(s)
      Hayashi, C., Ono, Y., Doi, N., Kitamura, F., Tagami, M., Mineki, R., Arai, T., Taguchi, H., Yanagida, M., Hirner, S., Labeit, D., Labeit, S., Sorimachi, H.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 14801-14814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] The importance of conserved amino acid residues in protease sub-domain Iib and the IS2 region in p94 for constitutive autolysis.2008

    • Author(s)
      Ono, Y., Hayashi, C., Doi, N., Tagami, M., and Sorimachi, H.
    • Journal Title

      FEBS Lett. 582

      Pages: 691-698

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] A simple single-cell chemical lysis method for analyses of intracellular molecules using an array of picoliter-scale microwells2008

    • Author(s)
      Sasuga, Y., Iwasawa, T., Terada, K., Oe, Y., Sorimachi, H., Ohara, O., Harada, Y.
    • Journal Title

      Anal. Chem. 80

      Pages: 9141-9149

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis.2008

    • Author(s)
      Koyama S, HataS, Witt CC, Ono Y, Lerche S, Ojima K, Chiba T, Doi N, Kitamura F, Tanaka K, Abe K, Witt SH, Rybin V, Gasch A, Franz T, Labeit S, Sorimachi H
    • Journal Title

      J Mol Biol

      Volume: 376 Pages: 1224-1236

    • DOI

      10.1016/j.jmb.2007.11.049

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] The importance of conserved amino acid residues in p94 protease sub-domain IIb and the IS2 region for constitutive autolysis.2008

    • Author(s)
      Ono Y, Hayashi C, Doi N, Tagami M, Sorimachi H
    • Journal Title

      FEBS Lett

      Volume: 582 Pages: 691-698

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Muscle RING-finger protein MuRF1 as a connector of muscle energy metabolism and protein synthesis.2008

    • Author(s)
      Koyama S., Hata S., Witt C. C., Ono Y., Lerche S., Ojima K., Chiba T., Doi N., Kitamura F., Tanaka K., Abe K., Witt S., Rybin V., Gasch A., Franz T., Labeit S., Sorimachi H.
    • Journal Title

      J.Mol.Biol. 376

      Pages: 1224-1236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Muscle RING-Finger Protein MuRF1 as a Connector of Muscle Energy Metabolism and Protein Synthesis.2008

    • Author(s)
      Koyama, S.*, Hata, S.*, Witt, C. C.*, Ono, Y., Lerche, S., Ojima, K., Chiba, T., Doi, N., Kitamura, F., Tanaka, K., Abe, K., Witt, S., Rybin, V., Gasch, A., Franz, T., Labeit, S., and Sorimachi, H. (*equally contributed first authors)
    • Journal Title

      J. Mol. Biol. 376, (peer-reviewed)

      Pages: 1224-1236

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18380085
  • [Journal Article] A simple single-cell chemical lysis method for analyses of intracellular molecules using an array of picoliter-scale microwells.2008

    • Author(s)
      Sasuga Y., Iwasawa T., Terada K., Oe Y., Sorimachi H., Ohara O., Harada Y.
    • Journal Title

      Anal.Chem. 80

      Pages: 9141-9149

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Multiple molecular interactions implicate connectin/titin N2A region as a modulating scaffold for p94/caplain 3 activity in skeletal muscle.2008

    • Author(s)
      Hayashi, C., Ono, Y., Doi, N., Kitamura, F., Tagami, M., Mineki, R., Arai, T., Taguchi, H., Yanagida, M., Hirner, S., Labeit, D., Labeit, S., and Sorimachi, H.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 14801-14814

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] The importance of conserved amino acid residues in protease sub-domain IIb and the IS2 region in p94 for constitutive autolysis.2008

    • Author(s)
      Ono Y., Hayashi C., Doi N., Tagami M., Sorimachi H.
    • Journal Title

      FEBS Lett. 582

      Pages: 691-698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Journal Article] Multiple molecular interactions implicate the connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle.2008

    • Author(s)
      Hayashi C, Ono Y, Doi N, Kitamura F, Tagami M, Mineki R, Arai T, Taguchi H, Yanagida M, Hirner S, Labeit D, Labeit S, Sorimachi H
    • Journal Title

      J Biol Chem

      Volume: 283 Pages: 14801-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] A simple single-cell chemical lysis method for analyses of intracellular molecules using an array of picoliter-scale microwells.2008

    • Author(s)
      Sasuga, Y., Iwasawa, T., Terada, K., Oe, Y., Sorimachi, H., Ohara, O., and Harada, Y.
    • Journal Title

      Anal. Chem. 80

      Pages: 9141-9149

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Comprehensive survey of p94/calpain 3 substrates by comparative proteomics - Possible regulation of protein synthesis by p942007

    • Author(s)
      Ono, Y., Hayashi, C., Doi, N., Kitamura, F., Shindo, M., Kudo, K., Tsubata, T., Yanagida, M., Sorimachi, H
    • Journal Title

      Biotech. J 2

      Pages: 565-576

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Suppression of calpain-dependent cleavage of the CDK5 activator p35 to p25 by site-specific phosphorylation.2007

    • Author(s)
      Kamei H, Saito T, Ozawa M, Fujita Y, Asada A, Bibb JA, Saido TC, Sorimachi H, Hisanaga S
    • Journal Title

      J Biol Chem

      Volume: 282 Pages: 1687-1694

    • DOI

      10.1074/jbc.m610541200

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Myogenic stage, sarcomere length, and protease activity modulate localization of muscle-specific calpain.2007

    • Author(s)
      Ojima K, Ono Y, Doi N, Yoshioka K, Kawabata Y, Labeit S, Sorimachi H
    • Journal Title

      J Biol Chem

      Volume: 282 Pages: 14493-14504

    • DOI

      10.1074/jbc.m610806200

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Stomach-specific calpain, nCL-2/calpain 8, is active without calpain regulatory subunit and oligomerizes through C2-like domains.2007

    • Author(s)
      Hata S, Doi N, Kitamura F, Sorimachi H
    • Journal Title

      J Biol Chem

      Volume: 282 Pages: 27847-56

    • DOI

      10.1074/jbc.m703168200

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Stomach-specific calpain, nCL-2/calpain 8, is active without calpain regulatory subunit, and oligomerizes through C2-like domains.2007

    • Author(s)
      Hata, S., Doi, N., Kitamura, F., and Sorimachi, H.
    • Journal Title

      J. Biol. Chem. 282, (peer-reviewed)

      Pages: 27847-27856

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18380085
  • [Journal Article] Myogenic stage, sarcomere length and protease activity modulate localization ofmuscle-specific calpain2007

    • Author(s)
      Ojima, K., Ono, Y., Doi, N., Yoshioka, K., Kawabata, Y., Labeit, S., Sorimachi, H
    • Journal Title

      J. Biol. Chem 282

      Pages: 14493-14504

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Stomach-specific calpain, nCL-2/calpain 8, is activewithout calpain regulatory subunit, and oligomerizes through C2-like domains2007

    • Author(s)
      Hata, S., Doi, N., Kitamura, F., Sorimachi, H
    • Journal Title

      J. Biol. Chem 282

      Pages: 27847-27856

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Comprehensive survey of p94/calpain 3 substrates by comparative proteomics--possible regulation of protein synthesis by p94.2007

    • Author(s)
      Ono Y, Hayashi C, Doi N, Kitamura F, Shindo M, Kudo K, Tsubata T, Yanagida M, Sorimachi H
    • Journal Title

      Biotech J

      Volume: 2 Pages: 565-576

    • DOI

      10.1002/biot.200700018

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Crystal structure of neoculin : insights into its sweetness and taste-modifying activity.2006

    • Author(s)
      Shimizu-Ibuka, A., Morita, Y., Terada, T., Asakura, T., Nakajima, K., Iwata, S., Misaka, T., Sorimachi, H., Arai, S., Abe, K.
    • Journal Title

      J.Mol.Biol. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Nutrient-dependent multimerization of the mammalian target of rapamycin through the N-terminal HEAT repeat region.2006

    • Author(s)
      Takahara T, Hara K, Yonezawa K, Sorimachi H, Maeda T
    • Journal Title

      J Biol Chem

      Volume: 281 Pages: 28605-28614

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the β-subunit of coatomer complex, β-COP.2006

    • Author(s)
      Hata S, Koyama S, Kawahara H, Doi N, Maeda T, Toyama-Sorimachi N, Abe K, Suzuki K, Sorimachi H
    • Journal Title

      J Biol Chem

      Volume: 281 Pages: 11214-24

    • DOI

      10.1074/jbc.m509244200

    • NAID

      80019185214

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the β-subunit of coatomer complex, β-COP.2006

    • Author(s)
      Hata, S., Koyama, S., Kawahara, H., Doi, N., Maeda, T., Toyama-Sorimachi, N., Abe, K., Suzuki, K., and Sorimachi, H.
    • Journal Title

      J. Biol. Chem. 281, (peer-reviewed)

      Pages: 11214-11224

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18380085
  • [Journal Article] Suppressed disassembly of autolyzing p94/CAPN3 by N2A connectin/titin in a genetic reporter system.2006

    • Author(s)
      Ono Y, Torii F, Ojima K, Doi N, Yoshioka K, Kawabata Y, Labeit D, LabeitS, Suzuki K, Abe K, Maeda T, Sorimachi H
    • Journal Title

      J Biol Chem

      Volume: 281 Pages: 18519-31

    • DOI

      10.1074/jbc.m601029200

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Calpain system regulates the differentiation of adult primitive mesenchymal ST-13 adipocytes.2006

    • Author(s)
      Yajima Y, Sato M, Sorimachi H, Inomata M, Maki M, Kawashima S
    • Journal Title

      Endocrinology

      Volume: 147 Pages: 4811-4819

    • DOI

      10.1210/en.2005-1647

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] How do defects in proteolytic functions of skeletal muscle-specific calpain, p94/calpain 3, cause calpainopathy/LGMD2A?2006

    • Author(s)
      Sorimachi H, Ojima K, Yanagida M, Ogawa H, Hayashi C, Doi N, Ono Y
    • Journal Title

      Neuromuscul Disord

      Volume: 16

    • URL

      http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description.

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Neoculin, a taste-modifying protein, is recognized by human sweet taste receptor.2006

    • Author(s)
      Nakajima K, Asakura T, Oike H, Morita Y, Shimizu-Ibuka A, Misaka T, Sorimachi H, Arai S, Abe K
    • Journal Title

      Neuroreport

      Volume: 17 Pages: 1241-44

    • DOI

      10.1097/01.wnr.0000230513.01339.3b

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Effect of N2A connectin/titin on disassembly of p94/CAPN3 caused by auaolysis in IS2.2006

    • Author(s)
      Ono Y, Torii F, Ojima K, Doi N, Yoshioka K, Labeit D, Labeit S, Suzuki K, Abe K, Maeda T, Sorimachi H
    • Journal Title

      FEBS Journal

      Volume: 273 Supp1. Pages: 50-50

    • DOI

      10.1111/j.1742-4658.2006.05276.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Possible functions of p94 in connectin-mediated signaling pathways in skeletal muscle cells.2006

    • Author(s)
      Ojima, K., Ono, Y., Hata, S., Koyama, S., Doi, N., Sorimachi, H.
    • Journal Title

      J.Muscle Res.Cell Motil. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Spatio-temporal expression of muscle-specific calpain, p94/calpain 3, during myogenesis.2006

    • Author(s)
      Ojima K, Ono Y, Doi N, Labeit S, Sorimachi H
    • Journal Title

      Neuromuscul Disord

      Volume: 16

    • URL

      http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description.

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Suppressed disassembly of autolyzing p94/CAPN3 in a genetic reporter system2006

    • Author(s)
      Ono, Y., Torii, F., Ojima, K., Doi, N., Yoshioka, K., Kawabata, Y., Labeit, D., Labeit, S., Suzuki,K., Abe, K., Maeda, T., Sorimachi, H
    • Journal Title

      J. Biol. Chem 281

      Pages: 18519-18531

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Relationships between p94/CAPN3 and N2A connectin/titin in skeletal muscle under the normal and dystrophic conditions.2006

    • Author(s)
      Ono Y, Ojima K, Doi N, Hayashi C, Torii F, 40K, Labeit D, Labeit S, Suzuki K, Abe K, Maeda T, Sorimachi H
    • Journal Title

      Neuromuscul Disord

      Volume: 16

    • URL

      http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description.

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the β-subunitof coatomer complex2006

    • Author(s)
      Hata, S., Koyama, S., Kawahara, H., Doi, N., Maeda, T., Toyama-Sorimachi, N., Abe, K., Suzuki, K., Sorimachi, H
    • Journal Title

      β-COP. J. Biol. Chem 281

      Pages: 11214-11224

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Crystal structure of neoculin: insights into its sweetness and taste-modifying activity.2006

    • Author(s)
      Shimizu-Ibuka A, Morita Y, Terada T, Asakura T, Nakajima K, Iwata S, Misaka T, Sorimachi H, Arai S, Abe K
    • Journal Title

      J Mol Biol

      Volume: 359 Pages: 148-158

    • DOI

      10.1016/j.jmb.2006.03.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the β-subunit of coatomer complex, β-COP.2006

    • Author(s)
      Hata, S., Koyama, S., Kawahara, H., Doi, N., Maeda, T., Toyama-Sorimachi, N., Abe, K., Suzuki, K., Sorimachi, H.
    • Journal Title

      J Biol.Chem. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Extracellular production of a heterodimeric protein, neoculin, with sweet-tasting and taste-modifying activities by Aspergillus oryzae.2006

    • Author(s)
      Nakajima, K., Asakura, T., Maruyama, J., Morita, J., Oike, H., Shimizu-Ibuka, A., Misaka, Misaka, T., Sorimachi, H., Arai, S., Kitamoto, K., Abe, K.
    • Journal Title

      Appl.Environ.Microbiol. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Extracellular production of neoculin, a sweet-tasting heterodimeric protein with taste-modifying activity, by Aspergillus oryzae.2006

    • Author(s)
      Nakajima K, Asakura T, Maruyama J, Morita Y, Oike H, Shimizu-Ibuka A, Misaka T, Sorimachi H, Arai S, Kitamoto K, Abe K
    • Journal Title

      Appl Environ Microbiol

      Volume: 72 Pages: 3716-3723

    • DOI

      10.1128/aem.72.5.3716-3723.2006

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Journal Article] Inhibitory NK receptor Ly49Q is expressed on subsets of dendritic cells in a cellular maturation- and cytokine stimulation-dependent manner.2005

    • Author(s)
      Toyama-Sorimachi, N.
    • Journal Title

      J.Immun. 174

      Pages: 4621-4629

    • Data Source
      KAKENHI-PROJECT-16026209
  • [Journal Article] Constitutive activation of the pH-responsive Rim 101 pathway in yeast mutants defective in late steps of the MVB/ESCRT pathway.2005

    • Author(s)
      Hayashi, M., Fukuzawa, T., Sorimachi, H., Maeda, T.
    • Journal Title

      Mol.Cell.Biol. 174

      Pages: 4621-4629

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Inhibitory NK receptor Ly49Q is expressed on subsets of dendritic cells in a cellular maturation- and cytokine stimulation-dependent manner.2005

    • Author(s)
      Toyama-Sorimachi, N., Omatsu, Y., Onoda, A., Tsujimura, Y., Iyoda, T., Maki, A., Sorimachi, H., Dohi, T., Taki, S., Inaba, K., Karasuyama, H.
    • Journal Title

      J.Immun. 25

      Pages: 9478-9490

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Inhibitory NK receptor Ly49Q is expressed on subsets of dendritic cells in a cellular maturation- and cytokine stimulation-dependent manner.2005

    • Author(s)
      Toyama-Sorimachi, N., Omatsu, Y., Onoda, A., Tsujimura, Y., Iyoda, T., Maki, A., Sorimachi, H., Dohi, T., Taki, S., Inaba, K., Karasuyama, H.
    • Journal Title

      J.Immun. (in press)

    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Inhibitory NK receptor Ly49Q is expressed on subsets of dendritic cells in a cellular maturation-and cytokine stimulation-dependent manner.2005

    • Author(s)
      Toyama-Sorimachi, N.
    • Journal Title

      J.Immun. 174

      Pages: 4621-4629

    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Inhibitory NK receptor Ly49Q is expressed on subsets of dendritic cells in a cellular maturation- and cytokine stimulation-dependent manner.2005

    • Author(s)
      Toyama-Sorimachi, N., Omatsu, Y., Onoda, A., Tsujimura, Y., Iyoda, T., Maki, A., Sorimachi, H., Dohi, T., Taki, S., Inaba, K., Karasuyama, H.
    • Journal Title

      J.Immun. (in press)

    • Data Source
      KAKENHI-PROJECT-16026209
  • [Journal Article] Possible functions of p94 in connectin-mediated signaling pathways in skeletal muscle cells2005

    • Author(s)
      Ojima, K., Ono, Y., Hata, S., Koyama, S., Doi, N., Sorimachi, H.
    • Journal Title

      J.Muscle Res.Cell Motil (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Inhibitory NK receptor Ly49Q is expressed on subsets of dendritic cells in a cellular maturation-and cytokine stimulation-dependent manner.2005

    • Author(s)
      Toyama-Sorimachi, N., Omatsu, Y., Onoda, A., Tsujimura, Y., Iyoda, T., Maki, A., Sorimachi, H., Dohi, T., Taki, S., Inaba, K., Karasuyama, H.
    • Journal Title

      J.Immun. 174

      Pages: 4621-4629

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Inhibitory NK receptor Ly49Q is expressed on subsets of dendritic cells in a cellular maturation- and cytokine stimulation-dependent manner.2005

    • Author(s)
      Toyama-Sorimachi, N.
    • Journal Title

      J.Immun. 174

      Pages: 4621-4629

    • Data Source
      KAKENHI-PROJECT-17028055
  • [Journal Article] Inhibitory NK receptor Ly49O is expressed on subsets of dendritic cells in a cellular maturation- and cytokine stimulation-dependent manner.2005

    • Author(s)
      Toyama-Sorimachi, N.
    • Journal Title

      J. Immun. 174

      Pages: 4621-4629

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Calpain.2004

    • Author(s)
      Sorimachi, H., Ono, Y.
    • Journal Title

      Encyclopedia of Biological Chemistry(eds., W.J.Lennarz, M.D.Lane)(Elsevier, Oxford) vol.1

      Pages: 300-306

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Calpain.2004

    • Author(s)
      Sorimachi, H., Ono, Y.
    • Journal Title

      in "Encyclopedia of Biological Chemistry" (Elsevier, Oxford; eds., W.J.Lennarz, M.D.Lane) Vol.1

      Pages: 300-306

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Degradation of fodrin by m-calpain in fibroblasts adhering to fibrillar collagen I gel.2004

    • Author(s)
      Sato, K., Hattori, S., Irie, S., Sorimachi, H., Inomata, M., Kawashima, S.
    • Journal Title

      J.Biochem 136

      Pages: 777-785

    • NAID

      10016204238

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Induction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signaling.2004

    • Author(s)
      Witt, C.C.*, Ono, Y.*, Puschmann, E., McNabb, M., Wu, Y., Gotthardt, M., Witt, S.H., Haak, M., Labeit, D., Gregorio, C.C., Sorimachi, H., Granzier, H., Labeit, S.(*equally contributed first authors)
    • Journal Title

      J.Mol.Biol. 336

      Pages: 145-154

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Possible regulation of the conventional calpain system by skeletal muscle-specific calpain, p94/calpain 3.2004

    • Author(s)
      Ono, Y., Kakinuma, K., Torii, F., Irie, A., Nakagawa, K., Labeit, S., Abe, K., Suzuki, K., Sorimachi, H.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 2761-2771

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Possible regulation of the conventional calpain system by skeletal muscle-specific calpain, p94/calpain 3.2004

    • Author(s)
      Ono, Y., Kakinuma, K., Torii, F., Irie, A., Nakagawa, K., Labeit, S., Abe, K., Suzuki, K., Sorimachi, H.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 2761-2771

    • Data Source
      KAKENHI-PROJECT-16026209
  • [Journal Article] Calpain.2004

    • Author(s)
      Sorimachi, H., Ono, Y.
    • Journal Title

      Encyclopedia of Biological Chemistry (eds., W.J.Lennarz and M.D.Lane)(Elsevier, Oxford) 1

      Pages: 300-306

    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Degradation of fodrin by m-calpain in fibroblasts adhering to fibrillar collagen I gel.2004

    • Author(s)
      Sato, K., Hattori, S., Irie, S., Sorimachi, H., Inomata, M., Kawashima, S.
    • Journal Title

      J.Biochem. 136

      Pages: 777-785

    • NAID

      10016204238

    • Data Source
      KAKENHI-PROJECT-16026209
  • [Journal Article] Degradation of fodrin by m-calpain in fibroblasts adhering to fibrillar collagen I gel.2004

    • Author(s)
      Sato, K., Hattori, S., Irie, S., Sorimachi, H., Inomata, M., Kawashima, S.
    • Journal Title

      J.Biochem. 136

      Pages: 777-785

    • NAID

      10016204238

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Neoculin as a New Taste-modifying Protein Occurring in the Fruit of Curculigo latifolia.2004

    • Author(s)
      Shirasuka, Y., Nakajima, K., Asakura, T., Yamashita, H., Yamamoto, A., Hata, S., Nagata, S., Abo, M., Sorimachi, H., Abe, K.
    • Journal Title

      Biosci.Biotechnol.Biochem. 68

      Pages: 1403-1407

    • NAID

      10013287069

    • Data Source
      KAKENHI-PROJECT-16026209
  • [Journal Article] Neoculin as a New Taste-modifying Protein Occurring in the Fruit of Curculigo latifolia.2004

    • Author(s)
      Shirasuka, Y., Nakajima, K., Asakura, T., Yamashita, H., Yamamoto, A., Hata, S., Nagata, S., Abo, M., Sorimachi, H., Abe, K.
    • Journal Title

      Biosci.Biotechnol.Biochem. 68

      Pages: 1403-1407

    • NAID

      10013287069

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Calpain.2004

    • Author(s)
      Sorimachi, H., Ono, Y.
    • Journal Title

      Encyclopedia of Biological Chemistry(eds., W.J.Lennarz, M.D.Lane)(Elsevier, Oxford) 1

      Pages: 300-306

    • Data Source
      KAKENHI-PROJECT-16026209
  • [Journal Article] Possible regulation of the conventional calpain system by skeletal muscle-specific calpain, p94/calpain 3.2004

    • Author(s)
      Ono, Y., Kakinuma, K., Torii, F., Irie, A., Nakagawa, K., Labeit, S., Abe, K., Suzuki, K., Sorimachi, H.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 2761-2771

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Neoculin as a New Taste-modifying Protein Occurring in the Fruit of Curculigo latifolia.2004

    • Author(s)
      Shirasuka, Y., Nakajima, K., Asakura, T., Yamashita, H., Yamamoto, A., Hata, S., Nagata, S., Abo, M., Sorimachi, H., Abe, K.
    • Journal Title

      Biosci.Biotechnol.Biochem. 68

      Pages: 1403-1407

    • NAID

      10013287069

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Induction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signaling.2004

    • Author(s)
      Witt, C.C.^*, Ono, Y.^*, Puschmann, E., McNabb, M., Wu, Y., Gotthardt, M., Witt, S.H., Haak, M., Labeit, D., Gregorio, C.C., Sorimachi, H., Granzier, H., Labeit, S.(^*equally contributed first authors)
    • Journal Title

      J.Mol.Biol. 336

      Pages: 145-154

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Neoculin as a New Taste-modifying Protein Occurring in the Fruitof Curculigo latifolia.2004

    • Author(s)
      Shirasuka, Y., Nakajima, K., Asakura, T., Yamashita, H., Yamamoto, A., Hata, S., Nagata, S., Abo, M., Sorimachi, H., Abe, K.
    • Journal Title

      Biosci.Biotechnol.Biochem. 68

      Pages: 1403-1407

    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Structure, activation, and biology of calpain.2004

    • Author(s)
      Suzuki, K., Hata, S., Kawabata, Y., Sorimachi, H.
    • Journal Title

      Diabetes 53

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Degradation of fodrin by m-calpain in fibroblasts adhering to fibrillar collagen I gel.2004

    • Author(s)
      Sato, K., Hattori, S., Irie, S., Sorimachi, H., Inomata, M., Kawashima, S.
    • Journal Title

      J.Biochem. 136

      Pages: 777-785

    • NAID

      10016204238

    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Calpain.2004

    • Author(s)
      Sorimachi, H., Ono, Y.
    • Journal Title

      Encyclopedia of Biological Chemistry(Elsevier, Oxford ; eds., W.J.Lennarz, M.D.Lane) 1

      Pages: 300-306

    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Neoculin as a New Taste-modifying Protein Occurring in the Fruit of Curculigo latifolia.2004

    • Author(s)
      Shirasuka, Y., Nakajima, K., Asakura, T., Yamashita, H., Yamamoto, A., Hata, S., Nagata, S., Abo, M., Sorimachi, H., Abe, K.
    • Journal Title

      Biosce.Biotechnol.Biochem. 68

      Pages: 1403-1407

    • NAID

      10013287069

    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Calpain.2004

    • Author(s)
      Sorimachi, H., Ono, Y.
    • Journal Title

      Encyclopedia of Biological Chemistry(eds., W.J.Lennarz, M.D.Lane)(Elsevier, Oxford) 1

      Pages: 300-306

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Induction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signaling.2004

    • Author(s)
      Witt, C.C.^*, Ono, Y.^*, Puschmann, E., McNabb, M., Wu, Y., Gottharth, M., Witt, S.H., Haak, M., Labeit, D., Gregorio, C.C., Sorimachi, H., Granzier, H., Labeit, S.
    • Journal Title

      J.Mol.Biol. 336

      Pages: 145-154

    • Data Source
      KAKENHI-PROJECT-16026209
  • [Journal Article] Induction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signaling.2004

    • Author(s)
      Witt, C.C.^*, Ono, Y.^*, Puschmann, E., McNabb, M., Wu, Y., Gotthardt, M., Witt, S.H., Haak, M., Labeit, D., Gregorio, C.C., Sorimachi, H., Granzier, H., Labeit, S.
    • Journal Title

      J.Mol.Biol. 336

      Pages: 145-154

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Induction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signaling.2004

    • Author(s)
      Witt, C.C., Ono, Y., Puschmann, E., McNabb, M., Wu, Y., Gotthardt, M., Witt, S.H., Haak, M., Labeit, D., Gregorio, C.C., Sorimachi, H., Granzier, H., Labei, S.
    • Journal Title

      J.Mol.Biol. 336

      Pages: 145-154

    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Structure, activation, and biology of calpain.2004

    • Author(s)
      Suzuki, K., Hata, S., Kawabata, Y., Sorimachi, H.
    • Journal Title

      Diabetes 53

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Possible regulation of the conventional calpain system by skeletal muscle-specific calpain, p94/calpain3.2004

    • Author(s)
      Ono, Y., Kakinuma, K., Torii, F., Irie, A., Nakagawa, K., Labeit, S., Abe, K., Suzuki, K., Sorimachi, H.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 2761-2771

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Induction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signaling.2004

    • Author(s)
      Witt, C.C.^*, Ono, Y.^*, Puschmann, E., McNabb, M., Wu, Y., Gotthardt, M., Witt, S.H., Haak, M., Labeit, D., Gregorio, C.C., Sorimachi, H., Granzier, H., Labeit, S.
    • Journal Title

      J.Mol.Biol. 336

      Pages: 145-154

    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Newly identified exons encoding novel variants of p94/calpain3 are expressed ubiquitously and overlap the α-ulucosidase C gene.2003

    • Author(s)
      Kawabata, Y., Hata, S., Ono, Y., Ito, Y., Suzuki, K., Abe, K., Sorimachi, H.
    • Journal Title

      WEBS Lett. 555

      Pages: 623-630

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Newly identified exons encoding novel variants of p94/calpain3 are expressed ubiquitously and overlap the α-glucosidase C gene.2003

    • Author(s)
      Kawabata, Y., Hata, S., Ono, Y., Ito, Y., Suzuki, K., Abe, K., Sorimachi, H.
    • Journal Title

      FEBS Lett. 555

      Pages: 623-630

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Heterogeneous nuclear ribonucleoprotein K interacts with and is proteolyzed by calpain in vivo.2003

    • Author(s)
      Kimura, E., Abe, K., Suzuki, K., Sorimachi, H.
    • Journal Title

      Biosci.Biotechnol.Biochem. 67

      Pages: 3786-1796

    • NAID

      110002694302

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Heterogeneous nuclear ribonucleoprotein K interacts with and is proteolyzed by calpain in vivo.2003

    • Author(s)
      Kimura, E., Abe, K., Suzuki, K., Sorimachi, H.
    • Journal Title

      Biosci.Biotechnol.Biochem 67

      Pages: 1786-1796

    • NAID

      110002694302

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] カルパインと病態-構造活性相関からの考察-2003

    • Author(s)
      反町 洋之
    • Journal Title

      薬理学会誌 122・1

      Pages: 21-29

    • NAID

      130000085994

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15380089
  • [Journal Article] Defects of non-lysosomal proteolysis : Calpain3 deficiency.2002

    • Author(s)
      Sorimachi, H., Beckmann, J.S.
    • Journal Title

      Structural and Molecular Basis of Skeletal Muscle Diseases(ed., Karpati.G.) (ISN Neuropath.Press.Basel)

      Pages: 148-153

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Muscle-specific RING finger 1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein 1.2002

    • Author(s)
      McElhinny, A.S., Kakinuma, K., Sorimachi, H., Labeit, S., Gregorio, C.C.
    • Journal Title

      J.Cell Biol. 157

      Pages: 125-136

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Defects of non-lysosomal proteolysis : Calpain3 deficiency.2002

    • Author(s)
      Sorimachi, H., Beckmann, J.S.
    • Journal Title

      Structural and Molecular Basis of Skeletal Muscle Diseases(ed, Karpati, G.)(ISN Neuropath.Press, Basel)

      Pages: 148-153

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] C/EBP_is required for proteolytic cleavage of cyclin A by calpain 3 in myeloid precursor cells.2002

    • Author(s)
      Welm, A.L., Timchenko, N.A., Ono, Y., Sorimachi, H., Radomska, H.S., Tenen, D.G., Lekstrom-Himes, J., Darlington, G.J.
    • Journal Title

      J.Biol.Chem. 277

      Pages: 33848-33856

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Stable expression of calpain 3 from a muscle transgene in vivo : Immature muscle in transgenic mice suggests a role for calpain 3 in muscle maturation.2002

    • Author(s)
      Spencer, M.J., Guyon, J.R., Sorimachi, H., Potts, A., Richard, I., Herasse, M., Chamberlain, J., Dalkilic, I., Kunkel, L.M., Beckmann, J.S.
    • Journal Title

      Proc.Natl.Acad.Sci.U.S.A. 929

      Pages: 8874-8879

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Muscle-specific RING finger 1 interacts with titin to regulate sarcomeric M-line and thick filaments structure and may have nuclear functions via its interaction with glucocorticoid2002

    • Author(s)
      McElhinny, A.S., Kakinuma, K., Sorimachi, H., Labeit, S., Gregorio, C.C.
    • Journal Title

      J.Cell Biol. 157

      Pages: 125-136

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Stable expression of calpain 3 from a muscle transgene in vivo : Immature muscle in transgenic mice suggests a role for calpain 3 in muscle maturation.2002

    • Author(s)
      Spencer, M.J., Guyon, J.R., Sorimachi, H., Potts, A., Richard, I., Herasse, M., Chamberlain, J., Dalkilic, I., Kunkel, L.M., Beckmann, J.S.
    • Journal Title

      Proc.Natl.Acad.Sci.U.S.A. 99

      Pages: 8874-8879

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] C/EBP_is required for proteolytic cleavage of cyclin A by calpain 3 in myeloid precursor cells.2002

    • Author(s)
      Welm, A., L, Timchenko, N.A., Ono, Y., Sorimachi, H., Radomska, H.S., Tenen, D.G., Lekstrom-Himes, J., Darlington, G.J.
    • Journal Title

      J.Biol.Chem. 277

      Pages: 33848-33856

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Journal Article] Flexibility analysis and structure comparison of two crystal forms of calcium-free human m-calpain.2002

    • Author(s)
      Reverter, D., Braun, M., Femandez-Catalan, C., Strobl, S., Sorimachi, H., Bode, W.
    • Journal Title

      Biol Chem. 383

      Pages: 1415-1422

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380309
  • [Patent] 組換えヒトm-カルパインの調製方法2016

    • Inventor(s)
      反町洋之、秦勝志
    • Industrial Property Rights Holder
      反町洋之、秦勝志
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-04-02
    • Acquisition Date
      2017-03-03
    • Data Source
      KAKENHI-PROJECT-15H02389
  • [Presentation] カルパインの特性を規定する基質特異性の定量的構造活性相関解析2017

    • Author(s)
      大内 史子、小山傑、進藤 真由美、馬見塚拓、瀧川一学、尾嶋孝一、秦 勝志、小野 弥子、反町 洋之
    • Organizer
      日本農芸化学会2017年度大会
    • Place of Presentation
      京都女子大学(京都府京都市)
    • Year and Date
      2017-03-19
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] カルパイン-1と-2の機能差を示唆するプロテアーゼドメイン内の自己分解2017

    • Author(s)
      大内 史子、進藤 真由美、秦 勝志、反町 洋之
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] カルパイン3の自己分解と活性化について2017

    • Author(s)
      小野弥子、土井奈穂子、反町洋之
    • Organizer
      日本農芸化学会大会2017年度大会
    • Place of Presentation
      京都女子大学他(京都府京都市)
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-15H02389
  • [Presentation] カルパイン-1および-2の機能調節に関わる自己切断点2017

    • Author(s)
      大内 史子、進藤 真由美、秦 勝志、反町 洋之
    • Organizer
      第22回日本病態プロテアーゼ学会学術集会
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] カルパインの特性を規定する基質特異性の定量的構造-活性相関解析2017

    • Author(s)
      大内史子、小山傑、進藤真由美、馬見塚拓、瀧川一学、尾嶋孝一、秦勝志、小野弥子、反町洋之
    • Organizer
      日本農芸化学会大会2017年度大会
    • Place of Presentation
      京都女子大学他(京都府京都市)
    • Data Source
      KAKENHI-PROJECT-15H02389
  • [Presentation] カルパイン3の筋線維の分化への影響の遺伝子改変マウスを用いた解析2017

    • Author(s)
      伊藤義城、大内史子、三上恭平、反町洋之
    • Organizer
      第22回日本病態プロテアーゼ学会学術集会
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] カルパイン3欠損型およびプロテアーゼ活性欠失変異型マウスの比較プロテオミクスによる肢帯型筋ジストロフィー2A型発症機序の解析2016

    • Author(s)
      大内史子、進藤真由美、伊藤義城、小野弥子、秦勝志、今西美知子、反町洋之
    • Organizer
      日本農芸化学会大会
    • Place of Presentation
      札幌コンベンションセンター、北海道札幌市
    • Year and Date
      2016-03-29
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] Quantitative structure-acitivity relationship (QSAR) analysis of calpain substrate specificity---Can we predict cleavage by calpain?2016

    • Author(s)
      Shinkai-Ouchi F, Koyama S, Shindo M, Mamitsuka H, Ono Y, Sorimachi H.
    • Organizer
      FASEB Science Research Conferences, “The biology of Calpains in health and desease”
    • Place of Presentation
      米国 モンタナ州 ビッグスカイ
    • Year and Date
      2016-07-18
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] 乾癬発症におけるカルパインの関与とその機能解析2016

    • Author(s)
      秦勝志、山本圭、西藤泰昌、北村ふじ子、村上誠、反町洋之
    • Organizer
      日本病態プロテアーゼ学会第21回大会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2016-08-05
    • Data Source
      KAKENHI-PROJECT-15H02389
  • [Presentation] CALPAIN, a maverick protease.2016

    • Author(s)
      Sorimachi, H.
    • Organizer
      A3 Foresight Symposium
    • Place of Presentation
      新潟大学医学部(新潟県新潟市)
    • Year and Date
      2016-02-18
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02389
  • [Presentation] カルパインの基質切断部位の予測2016

    • Author(s)
      大内史子、小山傑、小野弥子、秦勝志、尾嶋孝一、進藤真由美、David deVerle、土井奈穂子、瀧川一学、馬見塚拓、反町洋之
    • Organizer
      日本病態プロテアーゼ学会第21回大会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2016-08-05
    • Data Source
      KAKENHI-PROJECT-15H02389
  • [Presentation] カルパインの基質部位の予測、第21回 日本病態プロテアーゼ学会2016

    • Author(s)
      2大内史子、小山傑、小野弥子、秦勝志、尾嶋孝一、進藤真由美、duVerle D., 土井奈緖子、瀧川一学、馬見塚拓、反町洋之
    • Organizer
      第21回 日本病態プロテアーゼ学会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2016-08-05
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] Proteomic approach for elucidation of calpains’ substrate specificities2016

    • Author(s)
      Shinkai-Ouchi F, Koyama S, Shindo M, Hata S, Ono Y, Mamitsuka H, Sorimachi H
    • Organizer
      医学研国際シンポジウム
    • Place of Presentation
      公益財団法人東京都医学総合研究所 (東京都世田谷区)
    • Year and Date
      2016-06-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] 肢帯型筋ジストロフィー2A型のモデルとしてのカルパイン3ノックアウトおよびプロテアーゼ活性欠失変異型マウスの比較プロテオーム解析2015

    • Author(s)
      大内史子、進藤真由美、伊藤義城、小野弥子、秦勝志、今西美知子、反町洋之
    • Organizer
      病態プロテアーゼ学会
    • Place of Presentation
      ANAクラウンプラザホテルグランコート名古屋、愛知県名古屋市
    • Year and Date
      2015-08-21
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] カルパインの基質切断部位の特異席解明に向けた網羅的解析2015

    • Author(s)
      大内史子、進藤真由美、小野弥子、秦勝志、反町洋之
    • Organizer
      日本農芸化学会大会
    • Place of Presentation
      岡山大学 岡山市
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] Calpain functions and muscle homeostasis/dystrophies2014

    • Author(s)
      Sorimachi H, Shinkai-Ouchi F, Tonami K, Ojima K, Doi N, Kitamura F, Hata S, Ono Y
    • Organizer
      2014 Yonsei BK21plus-Igakuken joint symposium
    • Place of Presentation
      延正大学、ソウル、大韓民国
    • Year and Date
      2014-06-19
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] Similarity and difference of substrate selectivities between two conventional calpains2014

    • Author(s)
      Shinkai-Ouchi F, Shindo M, Hata S, Ono Y, Sorimachi H
    • Organizer
      2014 Yosnei BK21plus-CBSM international joint symposium
    • Place of Presentation
      安東、大韓民国
    • Year and Date
      2014-06-20
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] カルパイン3ノックアウトマウス(CAPN3-KO)、プロテアーゼ活性欠失変異型マウス(CAPN3-CSKI)の表現型比較とCAPN3の非酵素的機能2014

    • Author(s)
      大内史子、小野弥子、秦勝志、今西美知子、反町洋之
    • Organizer
      病態プロテアーゼ学会
    • Place of Presentation
      千里ライフサイエンスセンター 大阪府豊中市
    • Year and Date
      2014-08-08
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] Muscle homeostasis modulated by calpains.2014

    • Author(s)
      Sorimachi H, Tonami K, Shinkai-Ouchi F, Hata S, Ojima K, Ono Y
    • Organizer
      XIVth Symposium on Proteases, Inhibitors and Biological Control.
    • Place of Presentation
      Portoroz, Slovenia
    • Year and Date
      2014-09-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670166
  • [Presentation] カルパイン機能不全と疾患 Calpains in health and disease2013

    • Author(s)
      反町洋之、秦勝志、礪波一夫、大内史子、小野弥子
    • Organizer
      日本薬学会第133回年会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-23247021
  • [Presentation] Muscle-specific calpain modulates stress response in muscle cells.2012

    • Author(s)
      Sorimachi, H.
    • Organizer
      The 3rd Japan-Korea Joint Symposium on Life Science
    • Place of Presentation
      Tokyo
    • Invited
    • Data Source
      KAKENHI-PROJECT-23247021
  • [Presentation] Calpin-3 and connectin/titin as physical stress sensor system for skeletal muscle.2012

    • Author(s)
      Sorimachi, H.
    • Organizer
      4th Sensing Biology Symposium
    • Place of Presentation
      Tokyo
    • Invited
    • Data Source
      KAKENHI-PROJECT-23247021
  • [Presentation] Towards understanding the enigmatic substrate specificity of calpains2012

    • Author(s)
      Sorimachi, H., duVerle, D., Hata, S., Tonami, K., Ouchi, F., Ojima, K., Takigawa, I., Mamitsuka, H. and Ono, Y.
    • Organizer
      XIIIth Symposium on Proteases, Inhibitors and Biological Control
    • Place of Presentation
      Portoroz, Slovenia
    • Invited
    • Data Source
      KAKENHI-PROJECT-23247021
  • [Presentation] 胃腸特異的カルパインはストレス性胃粘膜防御に関与する2011

    • Author(s)
      秦勝志、反町洋之
    • Organizer
      第29回Cytoprotection研究会特別講演
    • Place of Presentation
      京都
    • Year and Date
      2011-03-11
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Studies of titin signaling and CAPN3.2011

    • Author(s)
      Sorimachi, H., Ojima, K., and Ono, Y.
    • Organizer
      LGMD2A Workshop: Coalition to Cure Calpain 3(C3)
    • Place of Presentation
      Santa Monica, USA.
    • Year and Date
      2011-10-27
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] 胃腸特異的カルパインはストレス性胃粘膜防御に関与する2011

    • Author(s)
      反町洋之
    • Organizer
      第29回Cytoprotection研究会
    • Place of Presentation
      メルパルク京都(京都府)
    • Year and Date
      2011-03-11
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Unique properties of muscle-specific calpain and muscular dystrophy caused by its defect.2011

    • Author(s)
      Sorimachi, H., Ojima, K., and Ono, Y.
    • Organizer
      IPS2011 - Seventh General Meeting of the International Proteolysis Society
    • Place of Presentation
      San Diego, USA.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] 胃腸特異的カルパインはストレス性胃粘膜防御に関与する2011

    • Author(s)
      反町洋之
    • Organizer
      第29回Cytoprotection研究会
    • Place of Presentation
      メルパルク京都(京都府)(招待講演)
    • Year and Date
      2011-03-11
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Skeletal muscle-specific calpain is an intracellular Ca^<2+> and Na^+-dependent protease.2011

    • Author(s)
      Sorimachi, H., Ojima, K., Takaya, E., and Ono Y.
    • Organizer
      CaBP17 - The 17th International Symposium on Ca^<2+>-binding proteins and Ca^<2+> function in health and disease.
    • Place of Presentation
      Beijing, China.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Unique functions of mammalian unconventional calpains.2010

    • Author(s)
      Sorimachi, H., Hata, S., Ojima, K., Labeit, S., and Ono, Y.
    • Organizer
      FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
    • Place of Presentation
      Arizona, USA.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] タンパク質のリサイクル-私たちの体にある「エコ」なシステムについて-2010

    • Author(s)
      反町洋之
    • Organizer
      第29回東京都臨床医学総合研究所公開講演会
    • Place of Presentation
      東京
    • Year and Date
      2010-04-14
    • Data Source
      KAKENHI-ORGANIZER-18076008
  • [Presentation] Legacy: Structure-function relationships of calpain.2010

    • Author(s)
      Sorimachi, H., A Koichi Suzuki
    • Organizer
      FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
    • Place of Presentation
      Arizona, USA.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Skeletal muscle-specific calpain, p94/calpain-3, dynamically distributes in skeletal muscle cells to adapt to physical stress, defects of which cause muscular dystrophy.2010

    • Author(s)
      Ono Y., Ojima K., Torii F., Takaya E., Doi N., Nakagawa K., Hata S., Abe K., Sorimachi H.
    • Organizer
      15th International Congress of the World Muscle Society
    • Place of Presentation
      Kumamoto, Japan
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] 鈴木先生の哲学とカルパイン2010

    • Author(s)
      反町洋之
    • Organizer
      鈴木紘一先生メモリアルシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-07-06
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Unique functions of mammalian unconventional calpains2010

    • Author(s)
      Sorimachi, H.
    • Organizer
      FASEB Summer Research Conferences-The Biology of Calpains in Health & Disease
    • Place of Presentation
      Carefree, Arizona, USA(招待講演)
    • Year and Date
      2010-07-30
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] 鈴木紘一先生追悼講演「CANPからカルパインそしてCAPNへ」2010

    • Author(s)
      小野弥子,秦勝志,川原裕之,前田達哉,反町洋之
    • Organizer
      日本病態プロテアーゼ学会第15回大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-08-20
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Calpains-introduction2010

    • Author(s)
      Ono, Y., Hata, S., and Sorimachi, H.
    • Organizer
      CHUV(Le Centre Hospitalier Universitaire Vaudois) Special Seminar
    • Place of Presentation
      Lausanne, Swizerland.
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] 胃腸特異的G-カルパインはカルパイン8と9のヘテロ二量体であり胃粘膜保護に機能する2010

    • Author(s)
      秦勝志,阿部学,鈴木英紀,北村ふじ子,反町典子,阿部啓子,崎村建司,反町洋之
    • Organizer
      BMB2010シンポジウム「生命の鍵を握るタンパク質分解」
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] [Selected for oral presentation] Skeletal muscle-specific calpain, p94/calpain-3, dynamically distributes in skeletal muscle cells to adapt to physical stress, defects of which cause muscular dystrophy.2010

    • Author(s)
      Ojima K., Ono Y., Doi N., Kitamura F., Hata S., Kawabata Y., Suzuki K., Maeda T., Abe K., Nakao H., Aiba A., Nakao K., Suzuki H., Kawahara H., Witt C., Labeit S., Ottenheijm, C., Granzier H., Toyama-Sorimachi N., Sorimachi M., Sorimachi H.
    • Organizer
      15th International Congress of the World Muscle Society
    • Place of Presentation
      Kumamoto, Japan
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] (Selected for oral presentation) Characteristics of p94/calpain 3 as an intracellular Na^+-dependent protease2010

    • Author(s)
      Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., and Sorimachi, H.
    • Organizer
      FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
    • Place of Presentation
      Arizona, USA.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Calpains-introduction CHUV (Le Centre Hospitalier Universitaire Vaudois) Special Seminar2010

    • Author(s)
      小野弥子, 秦勝志, 反町洋之
    • Place of Presentation
      Lausanne, Swizerland
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] タンパク質のリサイクルと私たちの体の調子を整えるしくみについて2010

    • Author(s)
      反町洋之
    • Organizer
      第37回三省堂サイエンスカフェ〔日本農芸化学会シリーズ(12)〕
    • Place of Presentation
      東京
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-ORGANIZER-18076008
  • [Presentation] [The closing lecture] In Memoriam Koichi Suzuki : Calpains in muscles and stomach2010

    • Author(s)
      Ono Y., Hata S., Ojima K., Tonami K., Kitamura F., Ueno M., Takaya E., Granzier H., Labeit S., Sorimachi H.
    • Organizer
      12^<th> Symposium on Proteases, Inhibitors and Biological Control
    • Place of Presentation
      Portoroz, Slovenia
    • Year and Date
      2010-09-28
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] [The closing lecture] Unique functions of mammalian unconventional calpains.2010

    • Author(s)
      Sorimachi H., Hata S., Ojima K., Labeit S., Ono Y.
    • Organizer
      FASEB Summer Research Conferences-The Biology of Calpains in Health & Disease
    • Place of Presentation
      Arizona, USA
    • Year and Date
      2010-07-30
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] (Murachi Award-winning oral presentation)Possible interacting proteins for G-calpain, a novel gastrointestinal calpain complex of calpain 8/nCL-2 and calpain 9/nCL-4.2010

    • Author(s)
      Matsushita, G, Hata, S., and Sorimachi, H.
    • Organizer
      FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
    • Place of Presentation
      Arizona, USA.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] The closing lecture]In Memoriam Koichi Suzuki: Calpains in muscles and stomach XIIth Symposium on Proteases2010

    • Author(s)
      Ono, Y., Hata, S., Ojima, K., Tonami, K., Kitamura, F., Ueno, M., Takaya, E., Granzier, H., Labeit, S., and Sorimachi, H.
    • Organizer
      Inhibitors and Biological Control
    • Place of Presentation
      Portoroz, Slovenia.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] (Selected for oral presentation) Calpain 8/nCL-2 and Calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense2010

    • Author(s)
      Hata, S., Abe, M., Suzuki, H., Kitamura, F., Toyama-Sorimachi, N., Abe, K., Sakimura, K., and Sorimachi, H.
    • Organizer
      FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
    • Place of Presentation
      Arizona, USA.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] A Koichi Suzuki Legacy : Structure-function relationships of calpain.2010

    • Author(s)
      反町洋之
    • Organizer
      FASEB Summer Research Conferences-The Biology of Calpains in Health & Disease
    • Place of Presentation
      Arizona, USA
    • Year and Date
      2010-07-29
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] 鈴木先生の哲学とカルパイン2010

    • Author(s)
      反町洋之
    • Organizer
      鈴木紘一先生メモリアルシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-07-06
    • Data Source
      KAKENHI-ORGANIZER-18076008
  • [Presentation] Unique functions of mammalian unconventional calpains2010

    • Author(s)
      Hiroyuki Sorimachi.
    • Organizer
      FASEB Summer Research Conferences-The Biology of Calpains in Health & Disease
    • Place of Presentation
      Arizona, U.S.A.
    • Data Source
      KAKENHI-ORGANIZER-18076008
  • [Presentation] Calpain-3 and molecular interactions.2009

    • Author(s)
      Sorimachi H., Ojima K., Hata S., Ono Y.
    • Organizer
      Calpaines et Calpainopathies. VII^<es> Journees annuelles de la Societe Francaise de Myologie
    • Place of Presentation
      Hendaye, France
    • Year and Date
      2009-10-30
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Calpain-3 and molecular interactions. Calpaines et Calpainopathies.2009

    • Author(s)
      Sorimachi, H., Ojima, K., Hata, S., andOno, Y.
    • Organizer
      VIIes Journees annuelles de la SFM(Societe Francaise de Myologie)
    • Place of Presentation
      Hendaye, France.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Calpaines et Calpainopathies.2009

    • Author(s)
      Sorimachi, H.
    • Organizer
      VIIes Journees annuelles de la SFM (Societe Francaise de Myologie)
    • Place of Presentation
      Hendaye,France
    • Year and Date
      2009-10-30
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] カルパインの多彩な生理機能とその破綻による病態2009

    • Author(s)
      反町洋之,小野弥子,秦勝志,尾嶋孝一
    • Organizer
      第82回日本生化学会大会シンポジウム「プロテオリシスの多彩な生理機能とその破綻による病態」
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Roles of skeletal muscle-specific calpain, p94/calpain 3, on multiple molecular interactions using connectin/titin N2A region as a modulating scaffold2008

    • Author(s)
      Sorimachi, H
    • Organizer
      11th International Symposium on PROTEINASE INHIBITORS AND BIOLOGICAL CONTROL
    • Place of Presentation
      Portoroz, Slovenia
    • Year and Date
      2008-09-02
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] カルパイン及びコネクチンの構造-病態生理相関(Structure-Pathophysiological-Function Relationships of Calpain and Connectin/Titin.)2008

    • Author(s)
      反町洋之、小野弥子、尾嶋孝一、林智佳子、土井奈穂子、北村ふじ子、小山傑、楠畑かおり、秦勝志、Labeit, S.
    • Organizer
      第8回日本蛋白質科学会年会 シンポジウム「蛋白質の輪廻転生-セントラルドグマを超えて」
    • Place of Presentation
      東京
    • Year and Date
      2008-06-12
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Roles of skeletal muscle-specific calpain, p94/calpain 3, on multiple molecular interactions using connectin/titin N2A region as a modulating scaffold2008

    • Author(s)
      Sorimachi, H., Hayashi, C., Hata, S., Ojima, K., Koyama, S., Doi, N., Kitamura, F., Takaya, E., Ueno, M., Kaneko, N., Ono, Y.
    • Organizer
      11th International Symposium on PROTEINASE INHIBITORS AND BIOLOGICAL CONTROL
    • Place of Presentation
      Portoroz, Slovenia
    • Year and Date
      2008-09-02
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] La calpaina como "proteina moduladora" en la enfermedad y la salud. (Calpain as a "modulator protease" in health and muscle disease.)2008

    • Author(s)
      Sorimachi, H
    • Organizer
      UPV/EHU (Universidad del Pais Vasco/Euskal Herriko Unibertsitatea) Summer Course Symposium: Distrofias por Deficit de Calpaina-3: Una Vision General
    • Place of Presentation
      San Sebastian, Spain
    • Year and Date
      2008-07-14
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Lacalpaina como "proteina moduladora" en la enfermedad y la salud.(Calpain as a "modulator protease" in health and muscle disease.)2008

    • Author(s)
      Sorimachi, H.
    • Organizer
      UPV/EHU(Universidad del Pais Vasco/Euskal Herriko Unibertsitatea) Summer Course Symposium: Distrofias por Deficit de Calpaina-3: Una Vision General
    • Place of Presentation
      San Sebastian, Spain.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Roles of skeletal muscle-specific calpain, p94/calpain 3, on multiple molecular interactions using connectin/titin N2A region as a modulating scaffold.2008

    • Author(s)
      Sorimachi H., Hayashi C., Hata S., Ojima K., Koyama S., Doi N., Kitamura F., Takaya E., Ueno M., Kaneko N., Ono Y.
    • Organizer
      11^<th> International Symposium on Proteinase Inhibitors and Biological Control
    • Place of Presentation
      Portoroz, Slovenia
    • Year and Date
      2008-09-02
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Roles of skeletal muscle-specific calpain, p94/calpain 3, on multiple molecular interactions using connectin/titin N2A region as a modulating scaffold.2008

    • Author(s)
      Sorimachi, H., Hayashi, C., Hata, S., Ojima, K., Koyama, S., Doi, N., Kitamura, F., Takaya, E., Ueno, M., Kaneko, N., and Ono, Y.
    • Organizer
      11th International Symposium on PROTEINASE INHIBITORS AND BIOLOGICAL CONTROL
    • Place of Presentation
      Portoroz, Slovenia.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Calpain as a "modulator protease" in health and muscle disease.2008

    • Author(s)
      反町洋之
    • Organizer
      Universidad del Pais Vasco/Euskal Herriko Unibertsitatea Summer Course Symposium : Distrofias por Deficit de Calpaina-3: Una Vision General
    • Place of Presentation
      San Sebastian, Spain
    • Year and Date
      2008-07-14
    • Data Source
      KAKENHI-PROJECT-20370055
  • [Presentation] Proteolytic regulation of creatine-kinase by muscle-specific RING-finger protein, MURF1.2008

    • Author(s)
      Koyama, S., Hata, S., Witt, C. C., Ono, Y., Ojima, K., Chiba, T., Doi, N., Kitamura, F., Tanaka, K., Abe, K., Witt, S., Labeit, S., and Sorimachi, H.
    • Organizer
      Nogei-kagakukai
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2008-03-28
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18380085
  • [Presentation] Unconventional calpains. FASEB Summer Research Conferences2007

    • Author(s)
      Sorimachi, H
    • Organizer
      The Biology of Calpains in Health & Disease
    • Place of Presentation
      Colorado, USA
    • Year and Date
      2007-07-15
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Toward Understanding Relationships between Proteolytic Activity of Skeletal Muscle-Specific Calpain and Calpainopathy2007

    • Author(s)
      Sorimachi, H
    • Organizer
      2007 Korea-Japan Joint Symposium "Protein Modification and Degradation in Human Diseases"
    • Place of Presentation
      Seoul, South Korea
    • Year and Date
      2007-09-05
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Toward Understanding Relationships between Proteolytic Activity of Skeletal Muscle-Specific Calpain and Calpainopathy.2007

    • Author(s)
      Ono, Y., Ojima, K., Hata, S., and Sorimachi, H.
    • Organizer
      2007 Korea-Japan Joint Symposium "Protein Modification and Degradation in Human Diseases"
    • Place of Presentation
      Seoul, South Korea.
    • Year and Date
      2007-09-05
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Novel approaches for analysis of proteolytic activity of muscle-specific calpain p94/calpain 32007

    • Author(s)
      Sorimachi, H
    • Organizer
      Xth International Symposium on PROTEINASE INHIBITORS AND BIOLOGICAL CONTROL: From single molecules to degradomics
    • Place of Presentation
      Portoroz, Slovenia
    • Year and Date
      2007-06-24
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Unconventional calpains2007

    • Author(s)
      Sorimachi, H.
    • Organizer
      FASEB Summer Research Conferences-The Biologyof Calpainsin Health & Disease
    • Place of Presentation
      Colorado,USA
    • Year and Date
      2007-07-15
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Unconventional calpains.2007

    • Author(s)
      Ono, Y., Ojima, K., Hayashi, C., Doi, N., Kitamura, F., Koyama, S., Hata, S., Labeit, S., Yanagida, M., Maeda, T., and Sorimachi, H.
    • Organizer
      FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
    • Place of Presentation
      Colorado, USA.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Enzymatic characterization of stomach-apecific calpain, nCL-2.2007

    • Author(s)
      Hata, S., Kitamura, F., Doi, N., and Sorimachi, H.
    • Organizer
      BMB2007
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2007-12-12
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18380085
  • [Presentation] Novel approaches for analysis of proteolytic activity of muscle-specific calpain p94/calpain 32007

    • Author(s)
      Ono, Y., Ojima, K., Hayashi, C., Doi, N., Kitamura, F., Koyama, S., Hata, S., Labeit, S., Yanagida, M., Maeda, T., and Sorimachi, H.
    • Organizer
      Xth International Symposium on PROTEINASE INHIBITORS AND BIOLOGICAL CONTROL: From single molecules to degradomics
    • Place of Presentation
      Portoroz, Slovenia.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Unconventional calpains.2007

    • Author(s)
      Sorimachi, H.
    • Organizer
      FASEB Summer Research Conferences-The Biology of Calpains in Health & Disease
    • Place of Presentation
      Colorado,USA
    • Year and Date
      2007-07-15
    • Data Source
      KAKENHI-PROJECT-19658057
  • [Presentation] How do defects in proteolytic functions of skeletal muscle-specific calpain, p94/calpain 3, cause calpainopathy/LGMD2A?2006

    • Author(s)
      Sorimachi, H., Ojima, K., Yanagida, M., Ogawa, H., Hayashi, C., Doi, N., and Ono, Y.
    • Organizer
      XIth International Congress on Neuromuscular Diseases
    • Place of Presentation
      Istanbul, Turkey.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Physiological functions of a stomach-specific calpain, nCL-2, in the mucus secreting cells.2006

    • Author(s)
      ata, S., Koyama, S., Kawahara, H., Doi, N., Maeda, T., Toyama-Sorimachi, N., Abe, K., Suzuki, K., and Sorimachi, H.
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress.
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2006-06-23
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18380085
  • [Presentation] A novel genetic assay system for a rapidly autolyzing muscle-specific calpain p94/calpain 32006

    • Author(s)
      Ono, Y., Torii, F., Ojima, K., Doi, N., Yoshioka, K., Kawabata, Y., Labeit, D., Labeit, S., Suzuki, K., Abe, K., Maeda, T., Hata, S., Koyama, S., and Sorimachi, H.
    • Organizer
      5^<th> Internationla Conference on Cysteine Proteinases and Their Inhitbitors: From Structure to Regulation and Biology
    • Place of Presentation
      Portoroz, Slovenia.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Novel function of calpain at the membranes.2006

    • Author(s)
      Sorimachi, H., Maeda, T., Suzuki, K.
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology and 11^<th> FAOBMB Congress.
    • Place of Presentation
      Kyoto, Japan.
    • Data Source
      KAKENHI-PLANNED-18076007
  • [Presentation] Extended concept for calpain “activity” – non-proteolytic functions of unconventional calpains.

    • Author(s)
      Sorimachi, H., Tonami, K., Shinkai-Ouchi, F., Hata, S., Ojima, K., and Ono, Y.
    • Organizer
      FASEB Summer Research Conferences &#8211; Biology of Calpains in Health & Disease
    • Place of Presentation
      Vermont, USA.
    • Year and Date
      2013-07-21 – 2013-07-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-23247021
  • 1.  SUZUKI Koichi (80011948)
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    # of Collaborated Products: 5 results
  • 2.  ISHIURA Shoichi (10158743)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 0 results
  • 3.  ONO Yasuko (20392376)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 98 results
  • 4.  HATA Shoji (10392375)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 62 results
  • 5.  INOMATA Mitsushi (30142649)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 6.  TOMIOKA Shigeo (90159046)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  ABE Keiko (10151094)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  OJIMA Koichi (60415544)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 31 results
  • 9.  MIZUSHIMA Noboru (10353434)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  IWAI Kazuhiro (60252459)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  SAKAI Yasuyoshi (60202082)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  MATSUOKA Kunie (40291158)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TONAMI Kazuo (70511393)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 14.  TAGAWA Kazuhiko (80245795)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  SAIDO Takaomi (80205690)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KIMURA Sumiko (50093232)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  IWASHITA Yoshiko (50111498)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  MAEDA Tatsuya (90280627)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  EMORI Yasufumi (60160389)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  NAKAO Masayuki (90242007)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SHINKAI-OUCHI Fumiko (00435710)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 17 results
  • 22.  富岡 茂雄 (90159054)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  平井 秀一 (80228759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  秋田 朗子 (40124432)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  杤尾 豪人 (70336593)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  千葉 智樹 (00311423)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  米川 博通 (30142110)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  KOMINAMI Eiki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  YOSHIDA Masasuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  NAGATA Kazuhiro
    # of Collaborated Projects: 1 results
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  • 32.  TANAKA Keiji
    # of Collaborated Projects: 1 results
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  • 33.  UCHIYAMA Yasuo
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    # of Collaborated Projects: 1 results
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  • 35.  BECKMANN Jacques
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    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
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  • 37.  TSUKANAOTO Yoshinori
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  SHINDO Mayumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 39.  ITOH Yoshiki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 40.  RICHARD Isab
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  NISHIYAMA Koichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  MATSUO Takashi
    # of Collaborated Projects: 0 results
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  • 43.  TAKAO Keizo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  MIYAZAKI Takuro
    # of Collaborated Projects: 0 results
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  • 45.  KAWAMURA Yumiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  饗場 篤
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  • 47.  宮川 剛
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    # of Collaborated Products: 1 results
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  • 49.  大西 紘二
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    # of Collaborated Products: 2 results

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