YONEKAWA Hiromichi 米川博通

… Alternative Names

Researcher Number	30142110
Other IDs
External Links
Affiliation (Current)	2019 : 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 研究員
Affiliation (based on the past Project Information) *help	2014 – 2019 : 公益財団法人東京都医学総合研究所, 基盤技術研究センター, 特任研究員 2015 : 公益財団法人東京都医学総合研究所, 客員研究員 2014 : 公益財団法人東京都医学総合研究所, 遺伝子改変動物室, 特任研究員 2013 : 公益財団法人東京都医学総合研究所, 基盤技術研究センター, 研究員 2011 : 東京都医学研究所, 基盤技術研究センター, センター長 … More
Review Section/Research Field	Principal Investigator Laboratory animal science / Laboratory animal science / Laboratory animal science / 遺伝 / Otorhinolaryngology Except Principal Investigator Biological Sciences / Laboratory animal science / Laboratory animal science / Virology / Immunology … More
Keywords	Principal Investigator トランスジェニックマウス / マウス / 遺伝子改変マウス / 遺伝子導入動物 / Cre / ヒト疾患モデル / ジフテリア毒素 / ヒト疾患モデルマウス / mtDNA / Nga … More Except Principal Investigator 野生マウス / ミトコンドリアDNA / C型肝炎ウイルス / Sox17 / トランスジェニックマウス / 持続感染 / マウス / X染色体 / Wild mouse / インターフェロン / mouse / 基準近交系マウス / 系統情報 / 腸管形成 / 遺伝的特性検査 / 内胚葉 / 胚凍結保存 / 遺伝子マッピング / Mitochondrial DNA / シグナル伝達 / 病態モデルマウス / ミトコンドリア / 腫瘍発生抑制遺伝子 / 修飾遺伝子 / mtDNA・Dル-プ / 老化 / 自然免疫 / ミトコンドリア病 / TL / Rice / C型肝炎ウィルス / HCV / 野生イネ / transgenic mouse / 感染性cDNAクローン / レトロポゾン / Sox18 / HSP70 / Subspecies group / 微生物特性検査 / rct gene / マウス先天性白内障 / Recombinant Inbred系統 / signal transduction / 遺伝子 / 自己免疫疾患 / 微生物的特性検査 / 免疫寛容 / リコンビナント・インブレッド系マウス / 日本産野生マウス / congenital cataract / コンジェニック系マウス / リコンビナント・インブレッド系統 / Igβ / gut formation / IRF-3 / B細胞分化 / Ribosomal DNA / Vcam-1 / ミトコンドリア遺伝子疾患 / 地理的分布 / modifier gene / Endoderm / 老化関連疾患 / リボソームDNA / 突然変異 / IRES / T細胞レセプタ- / ジフテリア毒素 / p53蛋白質 / disease model mouse / プレB細胞レセプター / Hー2組換ホットスポット / endoderm / cataract mouse / 肝がん / Geographical distribution / mtDNA / ノックアウトマウス / Modifier gene / 免疫抑制 / 動物モデル / 持続感染複製 / ヘモグロビン / 発生・分化 / Recombinant Inbred系マウス / TL遺伝子 / Congenic系マウス / WRN蛋白質 / 再構成ウイルス / 血管形成 / μH chain / Mouse ingerited cataract, / PKC / コンソミック / ES細胞 / ミトコンドリアノックアウト / cDNA塩基配列 / rheumatoid arthritis / Gene targeting / mrct遺伝子 / replication / Genetic background / 生殖系列キメラ / Hー2組換えホットスポット / ウレタン誘発染色体異常 / アトピー性皮膚炎 / 染色体Cバンド / 緑色蛍光色素 / 遺伝変異(地理的変異) / マウス遺伝子のマッピング / 品質管理 / ganglioside / ヘモグロビンβ鎖 / mitochondrial DNA / 動物地理 / 糖鎖 / disease model mice / subspecies / 発癌 / experimental animal / Sox07 / IgE / 野生マウス亜種 / 中国 / animal model / 亜種群 / ANO-1 / 血栓 / イネ / 一炭素代謝 / ミトコンドリア間相互作用 / molecular evolution / ジフテリアトキシン / autoantibody / 系列特異的細胞消去 / 臨床症状の多様性 / 進化 / population genetics / beta-hemoglobin genes / ロシア東部 / 再生医学 / high density lipoprotein / 胸線 / Hepatitis C Virus / ES / raft / マラリア腎症 / 脳マラリア / 栽培化 / コンソミック系統 / 呼吸欠損 / 病態モデル / Gut / Tgマウス / 病態モデルマス / quality check / 地理的分化 / 免疫グロプリン遺伝子再構成 / チトクロームb / がん / Persistent infection / マイクロサテライトマーカー / カルパイン / コレステロール / プロテオミクス解析 / マラリア原虫 / 修飾遺伝子座 / 高密度リポタンパク質 / 胚性幹細胞 / アナフィラキシー / 受精卵遺伝子治療 / monoclonal antibody / 獲得免疫 / プレB細胞 / モデル動物 / アラフィラキシー / レトロウイルス遺伝子 / Mitochondrial diseases / Diabetes mellitus / マイクロサテライトDNA / インスリン分泌細胞 / モデルマウス / Transgenic mouse / 代替軽鎖 / 卵黄嚢 / 生理学 / 胚型転写物 / マウス内在性ウイルス / ダニ抗原 / ミトコンドリアゲノム / 膠原病 / 遺伝学 / T細胞負の選択 / クローンマウス / sperm / 骨格形成遺伝子 / C型肝炎 / 組換えホットスポット / pre B cell receptor / 原因遺伝子座 / Genetic distance / 大型プレB細胞 / surrogate light chain / Mouse mtDNA / ES cell / 戻し交配 / Sox17因子 / ミトコンドリア呼吸欠損 / Asia / germ cells / 発癌感受性遺伝子 / 亜種グループ / TRECKマウス / RI系統 / mitochondrial diseases / development / apolipoprotein / 始原生殖細胞 / Human disease-model mouse / Cre/loxp / カハール介在細胞 / 中国大陸 / RTI / アレルゲン / China / 遺伝的背景 / 哺乳類 / 系統育成 / Hemoglobin variants / cholesterol / modifier genes / 後腸 / mouse mtDNA mutation / 剥製標本 / NCマウス / 疾病モデルマウス / tissue-specific expression / Srcファミリーキナーゼ / マウスBAC contig / 腫瘍発生制御遺伝子 / 低温抵抗性 / ポリオウイルス受容体遺伝子 / 獣医学 / gene therapy by nuclear transplantation / 糖尿病 / がん化 / 種分化 / 肝臓 / 実験動物 / リボゾームDNA / 抗体 / 核移植による遺伝子治療 / ヘテロプラズミー / DNA塩基配列 / ミトコンドリアがん転移原因説 / infectious cDNA / Ano-1 / 裁培化 / クローニング / Aging / 消化管 / 自己免疫 / Shmt2遺伝子 / アレルギー / 全能性 / T細胞 / 内在性ウイルス / 初期発生 / 遺伝変異 / backcross / ゲノム不安定化 / ヒト老化の可逆性 / トランスジェニックスマウス / 生理的役割 / Genetic differentiation of subspecies / 精子 / per B cell receptor (preBCR) / マウスmtDNA / 精子受精能 / レプリコン細胞 / ヒトの移動 / 組織特異的発現 / 卵白アルブミン / FISH analysis / autoimmune deseases / Retroposon / 好塩基球 / HCV遺伝子スイッチング発現 / Apoptosis / H-2 / 生物機能モデル系統 / マウス亜種グループ / ミトコンドリア遺伝病 / 胃 / ウイルス / 癌 / Negative selection of T cell / ヒト老化 / 中央アジア地域 / ミトコンリア間相互作用 / Mitochondria knockout / 生殖細胞 / auto-immune disease / カルシウム / 細胞質遺伝因子 / 蛋白質 / トランスフォーム / 異質性 / マウス細胞質遺伝子 / desease model mouse / HCV cDNAクローン / ウレタン誘発肺腫瘍 / アポリポタンパク質A-I / 感染症 / アポリポタンパク質 / 日本産野生動物 / Interval mapping of mouse genes, / NKκB / 連鎖解析 / プロテオリシス / リボゾ-ムDNA / マウスmtDNA突然変異 / ポリオウイルスレセプター遺伝子 / Human migraion / マウス細胞質遺伝因子 / T細胞レセプター / リボソーム蛋白遺伝子 / rct gene, / 画像データベース / 同胞異種 / 欠陥形成 / プロB細胞 / リボソーム遺伝子 / FISH / Mutation / mrct gene / Gut tube formation / gut endoderm / carbohydrate chain / immunodeficiency / linkage / pro B cell / 突然変異型mtDNA / microsatellite / ラフト / mtDNA突然変異 / 動脈硬化 / ウイルス抑制因子 / 遺伝的亜種分化 / liver / 原因遺伝子群 / shmt2遺伝子破壊マウス / c-kit / B cell differentiation / 遺伝的多型 / ロシア東部地域 / リボソ-ムDNA / 表層粘液細胞 / 胸腺 / siRNA / 細胞分裂阻害 / consomic / mtDNA欠損細胞 / kidney / 腎臓 / clone mice / atherosclerosis / poliovirus receptor gene / 分子進化 / ヘモグロビン遺伝子 / neuropathy / がん転移 / 胚性内胚葉 / 病態モデルマウス(ミトマウス) / Dimer formation / autoimmune disease / Hbb-w1 haplotype / 白内障マウス / mtDNA導入 / 突然変異型 mtDNA / intersubspecies recombinant / 相同組み換え / 低温低抗性 / YACクローン / totipotency / B cell development / ヘモグロビン・ベータ・w1 / 遺伝子再構成 / H-2複合遺伝子 / env遺伝子DNA / 急性リンパ性白血病 / サテライトDNA / ウズベキスタン / ミトコンドリア移植 / 紫外線感受性 / 免疫グロブリン遺伝子再構成 / pathogenesis / マイクロサテライト / ES cells / アポプトーシス / 神経症 / ミトコンドリア老化原因説 / Thymus / development and differentiation / Russia / 中国東北部地域 / 免疫不全症 / Gcnctic differentiation of subspeies / 白内障遺伝子 / Microsatellite DNA / rct遺伝子 / speciation / 遺伝子クローニング / W1型ヘモグロビン / ヘモグロビン変異 / gene cloning / 近交系ラット / 遺伝的組換ホットスポット / Interferon / mrct gene, / pre B cell / FISH分析 / 酵素 / 野生系統育成 / Subspccics group / 血栓性疾患 / 補体制御H蛋白 / 集団遺伝学 / フレンドウイルス抵抗性遺伝子 / chromosome / キメラ形成能 / マウス突然変異型mtDNA / zoogeography / ミトコンドリアゲノム変異 / cataract gene / germ-line chimera / Human migration / 疾患モデル / 遺伝的分化 / μH鎖 / thrombosis / ミトコンドリア遺伝子病 / チロシンリン酸化 / 自己抗体 / angiogenesis Less

Does age-associated down regulation of human SHMT2 and GCAT genes induce short lifespan or longevity?Ongoing
- Principal Investigator
  
  林純一
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  University of Tsukuba
マウス発生過程における異質性mtDNA分離モデル構築と操作技術への応用Ongoing
- Principal Investigator
  
  設楽浩志
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Investigation of age-associated mitochondrial disorders caused by mtDNA or unknown cytoplasmic genetic elements found in mouse strainsOngoing
- Principal Investigator
  
  林純一
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
中枢神経系・感覚器における部位および伝達物質特異的神経細胞除去法の開発Principal InvestigatorOngoing
- Principal Investigator
  
  米川博通
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Elucidation of regeneration mechanism of digestive tract pacemaker cell by modified TRECK method
- Principal Investigator
  
  Hori Masatoshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Integrative animal science
- Research Institution
  The University of Tokyo
Paradigm shift of mammalian mitochondrial genome using intercellular transfer technology
- Principal Investigator
  
  HAYASHI Jun-Ichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Generation and application of mouse models for neurodegenerative diseases by TRECK methodPrincipal Investigator
- Principal Investigator
  
  YONEKAWA Hiromichi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Development of mouse models for heteroplasmic mitochondrial DNA transmission
- Principal Investigator
  
  SHITARA Hiroshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Development of gene manipulation for mammalian mitochondrial DNAPrincipal Investigator
- Principal Investigator
  
  YONEKAWA Hiromichi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Bioimaging of mitochondrial dynamics and generation of model micePrincipal Investigator
- Principal Investigator
  
  YONEKAWA Hiromichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  財団法人東京都医学総合研究所
   Tokyo Metropolitan Organization for Medical Research
モデルマウスによるミトコンドリア病の治療原理とその開発Principal Investigator
- Principal Investigator
  
  米川博通
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Persistent infection of Hepatitis C virus to get over the acquired immunity system
- Principal Investigator
  
  KOHARA Michinori
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Analysis of entire physiological roles of mammalian mtDNA by generation of mice carrying various pathogenic mutations
- Principal Investigator
  
  HAYASHI Jun-ichi
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
2種類のプロモーターで制御可能なTRECK法(DPD-TRECK法)の開発Principal Investigator
- Principal Investigator
  
  米川博通
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
胃カルパインの粘膜特異的発現を応用した粘液分泌機構解析と食品の粘膜保護機能検索
- Principal Investigator
  
  反町洋之
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Food science
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
C型肝炎ウイルスによる遺伝子変異蓄積及び細胞不死化機序の解析
- Principal Investigator
  
  小原道法
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Trial of human tissue-substituted mice and its application to human diseases.Principal Investigator
- Principal Investigator
  
  YONEKAWA Hiromichi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Analysis of Common Genetic Factors for Allergy and Infectious Disease in NC Mice
- Principal Investigator
  
  TAMIO Ohno
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Nagoya University
系列特異的細胞消去法を応用した免疫細胞の生体内機能解析
- Principal Investigator
  
  烏山一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Medical and Dental University
Aberrant migration of primordial germ cells in the Sox 17^<-/-> mouse embryos
- Principal Investigator
  
  KANAI Masami
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kyorin University
C型肝炎ウイルスによる遺伝子変異蓄積及び細胞不死化機序の解析
- Principal Investigator
  
  小原道法
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
トランスジェニックマウスにおける導入遺伝子コピー数の測定法の開発と応用Principal Investigator
- Principal Investigator
  
  米川博通
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
C型肝炎ウイルスによる自然免疫及び獲得免疫系修飾機序の解析とその制御
- Principal Investigator
  
  小原道法
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
The role of Sox 17 during mouse gut formation.
- Principal Investigator
  
  KANAI Masami
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kyorin University
C型肝炎ウイルスの細胞および個体免疫系修飾による持続感染成立機序の解析とその制御
- Principal Investigator
  
  小原道法
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
C型肝炎ウイルスの持続複製による遺伝子不安定化と肝がん発症機序の解析とその制御
- Principal Investigator
  
  小原道法
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Redundant function of Sox17 and Sox18 in mouse angiogenesis
- Principal Investigator
  
  KANAI Yoshiakira
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  The University of Tokyo
C型肝炎ウィルスの細胞および個体免疫系修飾による持続感染成立機序の解析とその制御
- Principal Investigator
  
  小原道法
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Identification of cells or cell lineage responsible for atopic dermatitis-like skin lesions in model mice for human diseases by means of TRECK methodPrincipal Investigator
- Principal Investigator
  
  YONEKAWA Hiromichi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH
Impairment of the dimer formation of interferon regulatory factor-3 by hepatitis C virus core protein leads to evade interferon system
- Principal Investigator
  
  KOHARA Michinori
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Dynamism of B cell development
- Principal Investigator
  
  KARASUYAMA Hajime
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical and Dental University
ヒト先天性白内症モデルマウス、RCT,の原因遺伝子と修飾遺伝子の単離と機能解析
- Principal Investigator
  
  MAEDA Yukiko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  遺伝
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Application of disease-model mice with mutant mtDNA for precise investigation of its pathogenesis
- Principal Investigator
  
  HAYASHI Jun-Ichi
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  University of Tsukuba
C型肝炎ウィルスの細胞および個体免疫系修飾による持続感染成立機序の解析とその制御
- Principal Investigator
  
  KOHARA Michinori
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
ミトコンドリア遺伝子の異常を伴うヒト遺伝性難聴に対するモデルマウスの作製とその解析Principal Investigator
- Principal Investigator
  
  米川博通
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
A cell-autonomous activity of mouse Sox17 gene in mouse embryogenesis
- Principal Investigator
  
  KANAI Yoshiakira
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  THE UNIVERSITY OF TOKYO
Effect of different type of mitochondrial DNA on germline-differentiating potency of ES cell line in the mouse
- Principal Investigator
  
  NAGAO Yasumitsu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied animal science
- Research Institution
  KYOTO UNIVERSITY
Cloning of causative gene responsible for a new ingerited cataract in the mouse
- Principal Investigator
  
  MAEDA Yukiko Y.
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo Metropolitan Organization for Medical Science
慢性アレルギー疾患モデル動物の開発とアレルギー病態の解析
- Principal Investigator
  
  KARASUYAMA Hajime
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical and Dental University
  Tokyo Metropolitan Organization for Medical Research
Characterization of HCV replication and pathogenesis in animal model
- Principal Investigator
  
  KOHARA Michinori
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Virology
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
Functional analysis of mouse Sox17 gene by using the gene targeting method.
- Principal Investigator
  
  KANAI Yoshiakira
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  THE UNIVERSITY OF TOKYO
Russia-Japan Cooperative Survey and Breeding of Wild MicePrincipal Investigator
- Principal Investigator
  
  YONEKAWA Hiromichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  遺伝
- Research Institution
  Tokyo Organization for Medical Research, The Tokyo Metropolitan Institute of Medical Science
TOWARD TO POSITIONAL CLONING OF HUMAN POLYGENIC DISEASES USING MOUSE MODELS WITH SPECIAL REFERENCE TO ATOPIC DERMATITISPrincipal Investigator
- Principal Investigator
  
  YONEKAWA HIROMICHI
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH, THE TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE
Study on B cell differentiation signaling by using a novel system
- Principal Investigator
  
  KARASUYAMA Hajime
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical and Dental University
  Tokyo Metropolitan Organization for Medical Research
Evolutionary status of the genetic background in the wild mice and its participation in manifestation of the genes for biological functions in mouse models
- Principal Investigator
  
  MORIWAKI Kazuo
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Laboratory animal science
- Research Institution
  The Graduate University for Advanced Studies
Establishment of laboratory transgenic mouse strains for hepatitis C virus infectionPrincipal Investigator
- Principal Investigator
  
  YONEKAWA Hiromichi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Generation of model mice for auto immune neuropathy by transfection with anti-carbohydrate chain antibody genes.
- Principal Investigator
  
  TAI Tadashi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Animal model of autoimmune-induced atherosclerosis : Clinical significance of autoantibody against apolipoprotein A-I
- Principal Investigator
  
  UMEDA Masato
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
Cino-Japanese cooperative research on surveying genetic variants in Chinese wild mice and developing their inbred strains
- Principal Investigator
  
  MORIWAKI Kazuo
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  遺伝
- Research Institution
  The Graduate University for Advanced Studies
Analyzes of genes responsible for aging and the pathogenesis of diabetes by isolation of transgenic mice with pathogenic mtDNA mutation
- Principal Investigator
  
  HAYASHI Jun-ichi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
Establishement of in vivo Rescue Techniques for Mutant Genes by YAC-TransgenesisPrincipal Investigator
- Principal Investigator
  
  YONEKAWA Hiromichi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
Development of transgenic mice susceptible to orally-inoculated poliovirus
- Principal Investigator
  
  SHIROKI Kazuko
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Establishment of Mouse Consomic Lines
- Principal Investigator
  
  SHIROISHI Toshihiko
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  National Institute of Genetics
Analysis of transgenic mice expressing human HSP70
- Principal Investigator
  
  ISHII Ai
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
Establishment of Transgene Detection System with Mouse Tyrosinase Gene as a Visible Reporter GenePrincipal Investigator
- Principal Investigator
  
  YONEKAWA Hiromichi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
野生遺伝子の導入による生物機能モデル動物の開発
- Principal Investigator
  
  森脇和郎
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
Sino-Japnese cooperative studies on the genetic differentiation of Wild mice and rice.
- Principal Investigator
  
  MORIWAKI Kazuo
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Fukuyama University
  National Institute of Genetics
がん研究のための実験動物の維持と開発
- Principal Investigator
  
  森脇和郎
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Institute of Genetics
野生遺伝子の導入による生物機能モデル動物の開発
- Principal Investigator
  
  森脇和郎
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
がん研究のための実験動物の維持と開発
- Principal Investigator
  
  森脇和郎
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Institute of Genetics
野生遺伝子の導入による生物機能モデル動物の開発
- Principal Investigator
  
  森脇和郎
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
がん研究のための実験動物の維持と開発
- Principal Investigator
  
  MORIWAKI Kazuo
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Institute of Genetics
野生遺伝子の導入による生物機能モデル動物の開発
- Principal Investigator
  
  森脇和郎
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
Sino-Japanese cooperative studies on the genetics differentiation in the plants and animal in China
- Principal Investigator
  
  MORIWAKI Kazuo
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  National Institute of Genetics
Molecular Population Genetics of Japanese Wild Animal Species
- Principal Investigator
  
  MORIWAKI Kazuo
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  遺伝学
- Research Institution
  National Institute of Genetics
がん研究のための実験動物の維持と開発
- Principal Investigator
  
  森脇和郎
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Institute of Genetics
野生遺伝子の導入による生物機能モデル動物の開発
- Principal Investigator
  
  森脇和郎
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
哺乳動物による発癌制御の遺伝機構に関する研究
- Principal Investigator
  
  森脇和郎
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Institute of Genetics

[Book] 生物機能モデルと新しいリソース・リサーチツール2011
- Author(s)
  米川博通(編集)
- Total Pages
  671
- Publisher
  Life-Science Information Center(LIC)
- Data Source
  KAKENHI-PROJECT-21240044
[Book] 生物機能モデルと新しいリソース・リサーチツール2011
- Author(s)
  米川博通(編集)
- Total Pages
  671
- Publisher
  Life-Science Information Center(LIC)
- Data Source
  KAKENHI-PROJECT-21650102
[Book] Mouse Lab Manual (in Japanese)2003
- Author(s)
  Yonekawa, H. et al. ed.
- Total Pages
  376
- Publisher
  Springer Verlag Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208098
[Journal Article] Mechanistic insights into human pre-mRNA splicing of human ultra-short introns: potential unusual2018
- Author(s)
  Suzuki S, Hoshino H, Yoshida K, Nakanishi J, Tsuchiya-Hirata S, Kobuke S, Haruyama N, Nishimura F, Shiba H.
- Journal Title
  
  Biochemical and biophysical research communications.
  
  Volume : 495 Pages : 100-106
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K17135, KAKENHI-PROJECT-15K20009, KAKENHI-PROJECT-15H04354, KAKENHI-PROJECT-15K19316, KAKENHI-PROJECT-16K09809, KAKENHI-PROJECT-24592794, KAKENHI-PROJECT-25290038, KAKENHI-PROJECT-26461436, KAKENHI-PROJECT-15K18371, KAKENHI-PROJECT-25461363, KAKENHI-PROJECT-26860180, KAKENHI-PROJECT-15H02364, KAKENHI-PROJECT-13J02691, KAKENHI-PROJECT-24592514, KAKENHI-PROJECT-24592808, KAKENHI-PROJECT-25460392, KAKENHI-PROJECT-25830044, KAKENHI-PUBLICLY-26111518, KAKENHI-PUBLICLY-26117516, KAKENHI-PROJECT-24890233, KAKENHI-PROJECT-25461387, KAKENHI-PROJECT-11J06922, KAKENHI-PROJECT-21390248, KAKENHI-PROJECT-22500353, KAKENHI-PROJECT-22510221, KAKENHI-PROJECT-23650621, KAKENHI-PROJECT-23790501
[Journal Article] Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal2018
- Author(s)
  Tani H, Ohnishi S, Shitara H, Mito T, Yamaguchi M, Yonekawa H, Hashizume O, Ishikawa K, Nakada K, Hayashi JI.
- Journal Title
  
  Sci. Rep.
  
  Volume : 8 Pages : 425-425
- DOI
  10.1038/s41598-017-18828-3
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18535, KAKENHI-PROJECT-16K19034, KAKENHI-PROJECT-16H02463, KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-16H04688, KAKENHI-PROJECT-16K14719
[Journal Article] Establishment of a heteroplasmic mouse strain with interspecific mitochondrial DNA haplotypes and improvement of a PCR-RFLP-based measurement system for estimation of mitochondrial DNA heteroplasmy.2017
- Author(s)
  H. Shitara, L. Cao,　M. Yamaguchi,　H. Yonekawa、C. Taya
- Journal Title
  
  Transgenic Research
  
  Volume : 26 Pages : 559-565
- DOI
  10.1007/s11248-017-0009-2
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25290038, KAKENHI-PROJECT-24228005, KAKENHI-PROJECT-16H04688
[Journal Article] Skin CD4+ Memory T Cells Play an Essential Role in Acquired Anti-Tick Immunity through Interleukin-3-Mediated Basophil Recruitment to Tick-Feeding Sites2017
- Author(s)
  Ohta Takuya、Yoshikawa Soichiro、Tabakawa Yuya、Yamaji Kayoko、Ishiwata Kenji、Shitara Hiroshi、Taya Choji、Oh-hora Masatsugu、Kawano Yohei、Miyake Kensuke、Yamanishi Yoshinori、Yonekawa Hiromichi、Watanabe Naohiro、Kanuka Hirotaka、Karasuyama Hajime
- Journal Title
  
  Front Immunol
  
  Volume : 8 Pages : 1348-1348
- DOI
  10.3389/fimmu.2017.01348
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15719, KAKENHI-PROJECT-15H05786, KAKENHI-PROJECT-16H04688, KAKENHI-PROJECT-15K20969
[Journal Article] Essential Contribution of CD4+ T Cells to Antigen-Induced Nasal Hyperresponsiveness in Experimental Allergic Rhinitis2016
- Author(s)
  Nishimura, T., Kaminuma, O., Saeki, M., Kitamura, N., Matsuoka, K., Yoneyama, H., Mori, A., and Hiroi, T.
- Journal Title
  
  PLoS ONE
  
  Volume : １１
- DOI
  10.1371/journal.pone.0146686
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461497, KAKENHI-PROJECT-26860122, KAKENHI-PROJECT-16H04688, KAKENHI-PROJECT-25290038
[Journal Article] Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation in Cdh23.2016
- Author(s)
  Miyasaka Y, Shitara H, Suzuki S, Yoshimoto S, Seki Y, Ohshiba Y, Okumura K, Taya C, Tokano H, Kitamura K, Takada T, Hibino H, Shiroishi T, Kominami R, Yonekawa H, Kikkawa Y
- Journal Title
  
  Human Molecular Genetics
  
  Volume : 印刷中 Pages : 2045-2059
- DOI
  10.1093/hmg/ddw078
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J06119, KAKENHI-PROJECT-25430097, KAKENHI-PROJECT-25293058, KAKENHI-PROJECT-15H04291, KAKENHI-PROJECT-16H04688, KAKENHI-PROJECT-25290038, KAKENHI-PROJECT-15K18393
[Journal Article] Mouse somatic mutation orthologous to MELAS A3302G mutation in the mitochondrial tRNALeu(UUR) gene confers respiration defects2015
- Author(s)
  Shimizu A, Enoki S, Ishikawa K, Mito T, Obata K, Nagashima R, Yonekawa H, Nakada K, Hayashi J.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume : 467 Pages : 1097-102
- DOI
  10.1016/j.bbrc.2015.09.072
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23117005, KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-14J00467, KAKENHI-PROJECT-25290038
[Journal Article] G7731A mutation in mouse mitochondrial tRNA(Lys) regulates late-onset disorders in transmitochondrial mice.2015
- Author(s)
  Shimizu A, Mito T, Hashizume O, Yonekawa H, Ishikawa K, Nakada K, Hayashi J-I
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume : 459 Pages : 66-70
- DOI
  10.1016/j.bbrc.2015.02.070
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J00467, KAKENHI-PLANNED-23117005, KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-25640057, KAKENHI-PROJECT-25290038
[Journal Article] Administration of an Antioxidant Prevents Lymphoma Development in Transmitochondrial Mice Overproducing Reactive Oxygen Species2014
- Author(s)
  Yamanashi H, Hashizume O, Yonekawa H, Nakada K, Hayashi J.
- Journal Title
  
  Exp Anim.
  
  Volume : 63 Issue : 4 Pages : 459-466
- DOI
  10.1538/expanim.14-0038
- Language
  English
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25250011
[Journal Article] Administration of an antioxidant prevents lymphoma development in transmitochondrial mice overproducing reactive oxygen species.2014
- Author(s)
  Yamanashi H, Hashizume O, Yonekawa H, Nakada K, Hayashi J.
- Journal Title
  
  Exp Anim.
  
  Volume : 63 Pages : 459-466
- Acknowledgement Compliant / Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25290038
[Journal Article] Administration of an antioxidant prevents lymphoma development in transmitochondrial mice overproducing reactive oxygen species.2014
- Author(s)
  Yamanashi H, Hashizume O, Yonekawa H, Nakada K, Hayashi J.
- Journal Title
  
  Exp Anim.
  
  Volume : 63(4) Pages : 459-466
- Acknowledgement Compliant / Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640057
[Journal Article] Generation of mouse models for type 1 diabetes by selective depletion of pancreatic beta cells using toxin receptor-mediated cell knockout2013
- Author(s)
  K. Matsuoka, M. Saito, K. Shibata, M. Sekine, H. Shitara, C. Taya, Z. Zhang, T. Takahashi, K. Kohno, Y. Kikkawa & H. Yonekawa
- Journal Title
  
  Biochem Biophys. Res. Commun.
  
  Volume : 436 Pages : 400-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25290038
[Journal Article] Novel Basophil- or Eosinophil-Depleted Mouse Models for Functional Analyses of Allergic Inflammation2013
- Author(s)
  Matsuoka K, Shitara H, Taya C, Kohno K, Kikkawa Y, Yonekawa H.
- Journal Title
  
  PlosOne
  
  Volume : 8
- DOI
  10.1371/journal.pone.0060958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24228005, KAKENHI-PROJECT-25290038
[Journal Article] Comprehensive application of an mtDsRed2-Tg mouse strain for mitochondrial imaging.2012
- Author(s)
  Yamaguchi, J., Nishiyama, S., Shimanuki, M., Ono, T., Sato, A., Nakada, K., Hayashi, J-I., Yonekawa, H., Shitara, H
- Journal Title
  
  Transgenic Res
  
  Volume : 21巻 Pages : 439447-439447
- DOI
  10.1007/s11248-011-9539-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240044, KAKENHI-PROJECT-22650091, KAKENHI-PROJECT-22680035, KAKENHI-PROJECT-24700442
[Journal Article] Over-expression of Tfam improves the mitochondrial disease phenotypes in a mouse model system2010
- Author(s)
  Nishiyama, S., Shitara, H., Nakada, K., Ono, T., Sato, A., Suzuki, H., Ogawa, T., Masaki, H., Hayashi, J-I., Yonekawa, H
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume : 401巻 Pages : 26-31
- DOI
  10.1016/j.bbrc.2010.08.143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240044, KAKENHI-PROJECT-22650091, KAKENHI-PROJECT-22680035
[Journal Article] Generation of trans-mitochondrial mito-mice by the introduction of a pathogenic G13997A mtDNA from highly metastatic lung carcinoma cells.2010
- Author(s)
  Yokota, M., Shitara, H., Hashizume, O., Ishikawa, K., Nakada, K., Ishii, R., Taya, C., Takenaga, K., Yonekawa, H., Hayashi, J
- Journal Title
  
  FEBS Lett
  
  Volume : 584巻 Pages : 3943-3948
- DOI
  10.1016/j.febslet.2010.07.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240044, KAKENHI-PROJECT-22650091, KAKENHI-PROJECT-22680035
[Journal Article] Global imaging of mitochondrial morphology in tissues using transgenic mice expressing mitochondrially targeted enhanced green fluorescent protein2010
- Author(s)
  Shitara, H., Shimanuki, M., Hayashi, J-I., Yonekawa, H
- Journal Title
  
  Experimental Animals
  
  Volume : 59巻 Pages : 99-103
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20224174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240044
[Journal Article] Generation of trans-mitochondrial mito-mice by the introduction of a pathogenic G13997A mtDNA from highly metastatic lung carcinoma cells2010
- Author(s)
  Mutsumi Yokota, Hiroshi Shitara, Osamu Hashizume, Kaori Ishikawa, Kazuto Nakada, Rie Ishii, Choji Taya, Keizo Takenaga, Hiromichi Yonekawa, and Jun-Ichi Hayashi
- Journal Title
  
  FEBS Lett
  
  Volume : 84 Pages : 3943-3948
- URL
  https://www.tulips.tsukuba.ac.jp/dspace/handle/2241/106654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19100007
[Journal Article] The innate immune system in host mice targets cells with allogenic mitochondrial DNA2010
- Author(s)
  Kaori Ishikawa, Noriko Toyama-Sorimachi, Kazuto Nakada, Mami Morimoto, Hirotake Imanishi, Mariko Yoshizaki, Shigemi Sasawatari, Mamoru Niikura, Keizo Takenaga, Hiromichi Yonekawa, and Jun-Ichi Hayashi
- Journal Title
  
  J Exp. Med
  
  Volume : 207 Pages : 2297-2305
- URL
  https://www.tulips.tsukuba.ac.jp/dspace/handle/2241/107854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19100007
[Journal Article] Global imaging of mitochondrial morphology in tissues using transgenic mice expressing mitochondrially targeted enhanced green fluorescent protein2010
- Author(s)
  Hiroshi Shitara, Midori Shimanuki, Jun-Ichi Hayashi, Hiromichi Yonekawa
- Journal Title
  
  Exp. Anim. 59
  
  Pages : 99-103
- Data Source
  KAKENHI-PROJECT-19100007
[Journal Article] New evidence confirms that the mitochondrial bottleneck is generated without reduction of mitochondrial DNA content in early peimordial germ cells of mice2009
- Author(s)
  Liqin Cao, Hiroshi Shitara, Michihiko Sugimoto, Kuniya Abe, Jun-Ichi Hayashi, Hiromichi Yonekawa
- Journal Title
  
  PLoS Genet 5
- Data Source
  KAKENHI-PROJECT-19100007
[Journal Article] Disruption of IFN Signaling and HCV Synergistically Enhance Lymphoproliferation through Type II CD95 and Interleukins2009
- Author(s)
  Keigo Machida, Kyoko Tsukiyama-Kohara,Eiji Seike, ShigenobuTone, Yukiko Hayashi, Yuri Kasama, Masumi Shimizu, Hidemi Takahashi, Chyoji Taya, Hiromichi Yonekawa, Nobuyuki Tanaka, and Michinori Kohara
- Journal Title
  
  Gastroenterology
- Data Source
  KAKENHI-PROJECT-19041077
[Journal Article] New evidence confirms that the mitochondrial bottleneck is generated without reduction of mitochondrial DNA content in early primordial germ cells of mice2009
- Author(s)
  Cao, L., Shitara, H., Sugimoto, M., Hayashi, J.=I., Abe, K., Yonekawa, H.
- Journal Title
  
  PLoS genetics
  
  Volume : Vol5
- DOI
  10.1371/journal.pgen.1000756
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062013, KAKENHI-PROJECT-21240044
[Journal Article] Disruption of IFN Signaling and HCV Synergistically Enhance Lympho- proliferation through Type II CD95 and Interleukins.2009
- Author(s)
  K. Machida, K. Tsukiyama-Kohara, E. Seike, S. Tone, Y. Hayashi, Y. Kasama, M. Shimizu, H. Takahashi, C. Taya, H. Yonekawa, N. Tanaka, M. Kohara.
- Journal Title
  
  Gastroenterology in press
  
  Pages : 0-0
- Data Source
  KAKENHI-PROJECT-18200028
[Journal Article] Disruption of IFN Signaling and HCV Synergistically Enhance Lympho proliferation through Type II CD95 and Interleukins2009
- Author(s)
  K. Machida, H. Yonekawa, M. Kohara, et al.
- Journal Title
  
  Gastroenterology (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18200028
[Journal Article] The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells2007
- Author(s)
  Liqin Cao, Hiroshi Shitara, Takuro Horii, Yasumitsu Nagao, Hiroshi Imai, Kuniya Abe, Takahiko Hara, Jun-Ichi Hayashi, and Hiromichi Yonekawa
- Journal Title
  
  Nat. Genet
  
  Volume : 39 Pages : 386-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19100007
[Journal Article] Deletion-mutant mtDNA increases in somatic tissues but decreases in female germ cells with age2007
- Author(s)
  Akitsugu Sato, Kazuto Nakada, Hiroshi Shitara, Atsuko Kasahara, Hitomichi Yonekawa, and Jun-Ichi Hayashi
- Journal Title
  
  Geneics
  
  Volume : 177 Pages : 2031-2037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19100007
[Journal Article] Deletion-mutant mtDNA increases in somatic tissues but decreases in female germcells with age2007
- Author(s)
  Akitsugu Sato, Kazuto Nakada, Hiroshi Shitara, Atsuko Kasahara, Hiromichi Yonekawa, Jun-Ichi Hayashi
- Journal Title
  
  Genetics 177
  
  Pages : 2031-2037
- Data Source
  KAKENHI-PROJECT-19100007
[Journal Article] The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells.2007
- Author(s)
  Cao L, Shitara H, Horii T, Nagao Y, Imai H, Abe K, Hara T, Hayashi J, Yonekawa H.
- Journal Title
  
  Nat Gent. 39(3)
  
  Pages : 386-90
- Data Source
  KAKENHI-PROJECT-14GS0305
[Journal Article] The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells.2007
- Author(s)
  Cao L, Shitara H, Horii T, Nagao Y, Imai H, Abe K, Hara T, Hayashi J, Yonekawa H.
- Journal Title
  
  Nat Genet. 39(3)
  
  Pages : 386-90
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14GS0305
[Journal Article] The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells2007
- Author(s)
  Cao L, Shitara H, Horii T, Nagao Y, Imai I, Abe K, Hara T, Hayashi JI, Yonekawa H
- Journal Title
  
  Nature Genetis 39
  
  Pages : 386-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19100007
[Journal Article] The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells2007
- Author(s)
  Cao L, Shitara H, Horii T, Nagao Y, Imai H, Abe K, Hara T, Hayashi J, Yonekawa H.
- Journal Title
  
  Nat Genet 39(3)
  
  Pages : 386-90
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14GS0305
[Journal Article] Mitochondria-related male infertility.2006
- Author(s)
  Nakada K, Sato A, Yoshida K, Morita T, Tanaka H, Inoue S, Yonekawa H, Hayashi J.
- Journal Title
  
  Proc Natl Acad Sci U S A. 103(41)
  
  Pages : 15148-53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14GS0305
[Journal Article] Mitochondria-related male infertility2006
- Author(s)
  Nakada K, Sato A, Yoshida K, Morita T, Tanaka H, Inoue S, Yonekawa H, Hayashi J.
- Journal Title
  
  Proc Natl Acad Sci U S A. 103(41)
  
  Pages : 15148-53
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14GS0305
[Journal Article] Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation.2005
- Author(s)
  Sato A, Kono T, Nakada K, Ishikawa K, Inoue S, Yonekawa H, Hayashi J.
- Journal Title
  
  Proc Natl Acad Sci U S A. 102(46)
  
  Pages : 16765-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14GS0305
[Journal Article] Rare creation of recombinant mtDNA haplotypes in mammalian tissues.2005
- Author(s)
  Sato A, Nakada K, Akimoto M, Ishikawa K, Ono T, Shitara H, Yonekawa H, Hayashi J.
- Journal Title
  
  Proc Natl Acad Sci U S A. 102(17)
  
  Pages : 6057-62
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14GS0305
[Journal Article] Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α. ハ2005
- Author(s)
  Sasaki, J., Sasaki, T., Yamazaki, M., Matsuoka, M., Taya, C., Shitara, H., Takasuga, S., Nishino, M., Mizuno, K., Wada, T., Miyazai, H., Watanabe, H., Iizuka, R., Kubo, S., Murata, S, Chiba, T., Maehama, T., Hamad, K., Kishimoto, H., Frohman, M.A., Tanaka, K., Penninger, J.M., Yonekawa, H., Suzuki, A., Kanaho, Y.
- Journal Title
  
  J. Exp. Med. 201
  
  Pages : 859-870
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208098
[Journal Article] PCRの功罪 -親子鑑定、化石、そしてジュラシックパーク2005
- Author(s)
  米川博通
- Journal Title
  
  蛋白質核酸酵素「2005年11月増刊:二層膜オルガネラの遺伝学」(林純一他編集) 50・14
  
  Pages : 1912-1916
- Data Source
  KAKENHI-PROJECT-17650123
[Journal Article] Influence on spatiotemporal patterns of a male-specific Sox9 activation by ectopic Sry Expression during early phases of testis differentiation in mice.2005
- Author(s)
  Kidokoro, T., Matoba S., Hiramatsu, R., Fujisawa, M., Kanai-Azuma, M., Taya, C., Kurohmaru, M., Kawakami, H., Hayashi, Y., Kanai Y., Yonekawa, H.
- Journal Title
  
  Dev.Biol. 278
  
  Pages : 511-525
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580254
[Journal Article] Origins of mouse inbred strains deduced from whole-genome scanning by polymorphic microsatellite loci.2005
- Author(s)
  Sakai, T., Kikkawa, Y., Miura, I., Inoue, T., Moriwaki, K., Shiroishi, T., Satta, Y., Takahata, N., Yonekawa, H.
- Journal Title
  
  Mamm.Genome 16
  
  Pages : 11-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14540570
[Journal Article] Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation2005
- Author(s)
  Sato A, Kono T, Nakada K, Ishikawa K, Inoue S, Yonekawa H, Hayashi J.
- Journal Title
  
  Proc Natl Acad Sci U S A. 102(46)
  
  Pages : 16765-70
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14GS0305
[Journal Article] Origins of mouse inbred strains deduced from whole-genome scanning by polymorphic microsatellite loci.2005
- Author(s)
  Sakai, T., Kikkawa, Y., Miura, I., Inoue, T., Moriwaki, K., Shiroishi, T., Satta, Y., Takahata, N., Yonekawa, H.
- Journal Title
  
  Mamm.Genome 16
  
  Pages : 11-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208098
[Journal Article] Origins of mouse inbred strains deduced from whole-genome scanning by polymorphic microsatellite loci2005
- Author(s)
  Sakai, T., KikKawa, Y., Miura, I., Inoue, I., Moriwaki, K., Shiroishi, T., Satta, Y., Takahata, N., Yonekawa, H
- Journal Title
  
  Mamm. Genome 16
  
  Pages : 11-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208098
[Journal Article] Influence on spatiotemporal patterns of a male-specific Sox9 activation by ectopic Sry expression during early phases of testis differentiation in mice.2005
- Author(s)
  Kidokoro T., Matoba S., Hiramatsu R., Fujisawa M., Kanai-Azuma M, Taya C., Kurohmaru M., Kawakami H., Hayashi Y., Kanai Y., Yonekawa H.
- Journal Title
  
  Dev Biol. 278
  
  Pages : 511-525
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590152
[Journal Article] Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type Iα.2005
- Author(s)
  Sasaki, J., Sasaki, T., Yamazaki, M., Matsuoka, M., Taya, C., Shitara, H., Takasuga, S., Nishio, M., Mizuno, K., Wada, T., Miyazaki, H., Watanabe, H., Iizuka, R., Kubo, S., Murata, S., Chiba, T., Maehama, T., Hamada, K., Kishimoto, H., Frohman, M.A., Tanaka, K., Penninger, J.M., Yonekawa, H., Suzuki, A., Kanaho, Y.
- Journal Title
  
  J.Exp.Med. 201
  
  Pages : 859-870
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208098
[Journal Article] Rare creation of recombinant mtDNA haplotypes in mammalian tissues2005
- Author(s)
  Sato A, Nakada K, Akimoto M, Ishikawa K, Ono T, Shitara H, Yonekawa H, Hayashi J.
- Journal Title
  
  Proc Natl Acad Sci U S A. 102(17)
  
  Pages : 6057-62
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14GS0305
[Journal Article] Origins of mouse inbred strains deduced from whole-genome scanning by polymorphic microsatellite loci.2005
- Author(s)
  Sakai, T., Kikkawa, Y., Miura, I., Inoue, T., Moriwaki, K., Shiroishi, T., Satta, Y., Takahata, N., Yonekawa, H.
- Journal Title
  
  Mamm. Genome 16
  
  Pages : 11-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14540570
[Journal Article] A small deletion hotspot in the type II keratin gene mK6irs1/Krt2-6g on mouse chromosome 15, a candidate for causing the wavy hair of the caracul (Ca) mutation.2003
- Author(s)
  Kikkawa, Y., Oyama, A., Ishii, R., Miura, I., Amano, T., Ishii, R, Yoshikawa, Y., Masuya, H., Wakana, S., Shiroishi, T., Taya, C., Yonekawa, H.
- Journal Title
  
  Genetics 165
  
  Pages : 721-733
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14540570
[Journal Article] Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin.2003
- Author(s)
  Weil, D., El-Amraoui, A., Masmoudi, S., Mustapha, M., Kikkawa, Y., Laine, S., Delmaghani, S., Adato, A., Nadifi, S., Zina, Z.B., Hamel, C., Gal, A., Ayadi, H., Yonekawa, H., Petit, C.
- Journal Title
  
  Hum.Mol.Genet. 12
  
  Pages : 463-471
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14540570
[Journal Article] A small deletion hotspot in the type II keratin gene mK6irs1/Krt2-6g on mouse chromosome 15, a candidate for causing the wavy hair of the caracul (Ca) mutation.2003
- Author(s)
  Kikkawa Y, Oyama A, Ishii R, Miura I, Amano T, Ishii Y, Yoshiwaka Y, Masuya H, Wakana S, Shiroishi T, Taya C, Yonekawa H.
- Journal Title
  
  Genetics 165
  
  Pages : 721-733
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14540570
[Journal Article] Long-term maintenance of IgE-mediated memory in mast cells in the absence of detectable serum IgE2003
- Author(s)
  Kubo, S., Nakayama, T., Matsuoka, K., Yonekawa, H., Karasuyama, H
- Journal Title
  
  J. Immunol. 170
  
  Pages : 775-780
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208098
[Journal Article] Mutations in a new scaffold protein Sans cause deafness in Jackson shaker mice.2003
- Author(s)
  Kikkawa, Y., Shitara, H., Wakana, S., Kohara, Y., Takada, T., Okamoto, M., Taya, C., Kamiya, K., Yoshikawa, Y., Tokano, H., Kitamura, K., Shimizu, K., Wakabayashi, Y., Shiroishi, T., Kominami, R., Yonekawa, H.
- Journal Title
  
  Hum.Mol.Genet. 12
  
  Pages : 453-461
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14540570
[Journal Article] Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protem that associates with the USHIC protein, harmonin.2003
- Author(s)
  Weil.D, El-Amraoui A, Masmoudi S, Mustapha M, Kikkawa Y, Zina ZB, Hamel C, Gal A, Ayadi H, Yonekawa H, Petit C
- Journal Title
  
  Hum Mol Genet. 12
  
  Pages : 463-471
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14540570
[Journal Article] Long-term maintenance of IgE-mediated memory in mast cells in the absence of detectable serum IgE.2003
- Author(s)
  Kubo, S., Nakayama, T., Matsuoka, K., Yonekawa, H., Karasuyama, H.
- Journal Title
  
  J.Immunol. 170
  
  Pages : 775-780
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208098
[Journal Article] Mutations in a new scaffole protein Sans cause deafness in Jackson shaker mice.2003
- Author(s)
  Kikkawa Y, Shitara H, Wakana S, Kohara Y, Takada T, Okamoto M, Taya C, Kamiya K, Yoshikawa Y, Tokano H, Kitamura K, Shimizu K, Wakabayashi Y, Shiroishi T, Kominami R, Yonekawa H.
- Journal Title
  
  Hum Mol Genet. 12
  
  Pages : 453-461
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14540570
[Journal Article] Mitochondrial physiology and gene expression analyses reveal metabolic and translational dysregulation in oocyte-induced somatic nuclear reprogramming
- Author(s)
  Esteves, T. C., Psathaki, O. E., Pfeiffer, M. J., Balbach, S. T., Zeuschner, D., Shitara, H., Yonekawa, H., Siatkowski, M., Fuellen, G., Boiani, M
- Journal Title
  
  PLoS One
  
  Volume : (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240044
[Presentation] C57BL/6JおよびMus spretus由来ミトコンドリアゲノムを有する異質性マウス系統の開発2016
- Author(s)
  設楽浩志、曹麗琴、山口碧、米川博通、多屋長治
- Organizer
  第６３回日本実験動物学会総会
- Place of Presentation
  ミューザ川崎シンフォニーホール（神奈川県川崎市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-25430101
[Presentation] Proportion of large deleted mitochondrial DNA in single primary adherent cells from mouse tail2013
- Author(s)
  Midori Shimanuki, Junya Yamaguchi, Choji Taya, Hiromichi Yonekawa, Jun-Ichi Hayashi, Hiroshi Shitara
- Organizer
  International Symposium on Mitochondria 2013: The 13th Conference of Japanese Society of Mitochondrial Research and Medicine (J-Mit)
- Place of Presentation
  Roppongi Academyhills 49 (Tokyo, Japan)
- Data Source
  KAKENHI-PROJECT-25430101
[Presentation] １日の時間変化による組織ミトコンドリアDNA量の解析2013
- Author(s)
  島貫　碧、米川　博通、設楽　浩志
- Organizer
  第６０日本実験動物学会総会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Data Source
  KAKENHI-PROJECT-25430101
[Presentation] マウス初代接着性細胞におけるミトコンドリア核様体の挙動解析2013
- Author(s)
  山口　潤也、島貫　碧、米川　博通、設楽　浩志
- Organizer
  第６０日本実験動物学会総会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Data Source
  KAKENHI-PROJECT-25430101
[Presentation] ミトコンドリア転写因子A過剰発現によるミトコンドリア機能低下の抑制効果2011
- Author(s)
  設楽浩志、中田和人、林純一、米川博通
- Organizer
  第84回日本生化学会大会(シンポジウム)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21240044
[Presentation] マウスモデルを用いたTfam過剰発現によるミトコンドリア機能低下の抑制効果の解析2011
- Author(s)
  設楽浩志、西山哲史、中田和人、小野富男、佐藤晃嗣、鈴木英紀、小川哲弘、正木晴彦、林純一、米川博通
- Organizer
  第58日本実験動物学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21240044
[Presentation] Mitochondrial imaging of in tissues by using mtDsRed2-Tg mouse strain2011
- Author(s)
  Yamaguchi, J., Nishiyama, S., Shimanuki, M., Ono, T., Sato, A., Nakada, K., Hayashi, J-I., Yonekawa, H., Shitara, H
- Organizer
  The 10th Transgenic Technology Meeting(TT2011)
- Place of Presentation
  Florida, USA
- Data Source
  KAKENHI-PROJECT-21240044
[Presentation] マウスにおけるmtDNAの遺伝様式2010
- Author(s)
  設楽浩志、米川博通
- Organizer
  日本植物学会第74回大会
- Place of Presentation
  春日井、愛知県(招待講演)
- Data Source
  KAKENHI-PROJECT-21240044
[Presentation] マウスにおけるmtDNAの遺伝様式2010
- Author(s)
  設楽浩志、米川博通
- Organizer
  日本植物学会第74回大会
- Place of Presentation
  春日井、愛知県(招待講演)
- Data Source
  KAKENHI-PROJECT-21650102
[Presentation] マウス初代培養細胞におけるミトコンドリア速度解析2009
- Author(s)
  設楽浩志、佐藤晃嗣、島貫碧、林純一、米川博通
- Organizer
  第55日本実験動物学会総会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-21240044
[Presentation] 2種類のプロモーターで制御可能なTRECK法(DPD-TRECK法)の開発2009
- Author(s)
  山口潤也, 米川博通
- Organizer
  第56回日本実験動物学会総会
- Place of Presentation
  大宮ソニックシティー
- Data Source
  KAKENHI-PROJECT-19650109
[Presentation] Gene therapy of mitochondrial diseases in a mouse model2009
- Author(s)
  設楽浩志、西山哲史、中田和人、林純一、米川博通
- Organizer
  第32回日本分子生物学会年会.ワークショップ
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21240044
[Presentation] 標的細胞ノックアウト法の胎仔組織への応用2008
- Author(s)
  松岡邦枝、土屋真衣子、設楽浩志、松尾千古、河野憲二、米川博通
- Organizer
  日本実験動物科学技術2008(第55回日本実験動物学会総会・第42回日本実験動物技術者協会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-18200028
[Presentation] 標的細胞ノックアウト法の胎仔組織への応用2008
- Author(s)
  松岡邦枝、土屋真衣子、設楽浩志、松尾千古、河野憲二、米川博通
- Organizer
  BMB2008(第31回日本分子生物学会年会、第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18200028
[Presentation] 標的細胞ノックアウト法の胎仔組織への応用2008
- Author(s)
  松岡邦枝, 米川博通, 他
- Organizer
  (BMB2008)第31回日本分子生物学会年会、第81回日本生化学大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18200028
[Presentation] Improvement of a tissue-specific gene expression for TRECK method using a BAC clone2008
- Author(s)
  H. Yonekawa, K. Shibata, M. Sekine, K. Matsuoka, H. Shitara, C. Taya, T. Amano
- Organizer
  The 22nd International Mammalian Genome Conference (IMGC2008)
- Place of Presentation
  Prague, Czech
- Data Source
  KAKENHI-PROJECT-18200028
[Presentation] Improvement of a tissue-specific gene expression for TRECK method using a BAC clone.2008
- Author(s)
  Yonekawa, H., Shibata, K., Sekine, M., Matsuoka, K., Shitara, H., Taya, C. Amano, T.
- Organizer
  The 22nd International Mammalian Genome Conference (IMGC2008)
- Place of Presentation
  Prague, Czech
- Data Source
  KAKENHI-PROJECT-18200028
[Presentation] ヒト肝置換Tgマウスの作製方法2008
- Author(s)
  米川博通、松岡邦枝
- Organizer
  第7回研究交流フォーラム
- Place of Presentation
  東京
- Year and Date
  2008-02-27
- Data Source
  KAKENHI-PROJECT-18200028
[Presentation] 標的細胞ノックアウト法の胎仔組織への応用2008
- Author(s)
  松岡邦枝, 米川博通, 他
- Organizer
  日本実験動物科学技術2008(第55回日本実験動物学会総会・第42回日本実験動物技術者協会総会)
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-18200028

1. MORIWAKI Kazuo (50000229)

# of Collaborated Projects : 16results

# of Collaborated Products : 0results
2. SHITARA Hiroshi (90321885)

# of Collaborated Projects : 13results

# of Collaborated Products : 29results
3. KOHARA Michinori (10250218)

# of Collaborated Projects : 12results

# of Collaborated Products : 3results
4. TAYA Choji (90175456)

# of Collaborated Projects : 10results

# of Collaborated Products : 8results
5. SHIROISHI Toshihiko (90171058)

# of Collaborated Projects : 9results

# of Collaborated Products : 0results
6. KARASUYAMA Hajime (60195013)

# of Collaborated Projects : 7results

# of Collaborated Products : 3results
7. SHUDA Masahiro (10356256)

# of Collaborated Projects : 7results

# of Collaborated Products : 0results
8. 木南凌 (40133615)

# of Collaborated Projects : 6results

# of Collaborated Products : 0results
9. HAYASHI Jun-ichi (60142113)

# of Collaborated Projects : 6results

# of Collaborated Products : 21results
10. TSUCHIYA Kimiyuki (30155402)

# of Collaborated Projects : 6results

# of Collaborated Products : 0results
11. 高木信夫 (20001852)

# of Collaborated Projects : 6results

# of Collaborated Products : 0results
12. KIKKAWA Yoshiaki (20280787)

# of Collaborated Projects : 5results

# of Collaborated Products : 3results
13. ISHII Rie (00425688)

# of Collaborated Projects : 5results

# of Collaborated Products : 1results
14. SUZUKI Hitoshi (40179239)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
15. MIYASHITA Nobumoto (10190779)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
16. MATSUDA Yoichi (70165835)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
17. 小幡裕一 (30177290)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
18. MAEDA YUKIKO (40109947)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
19. MATSUOKA Kunie (40291158)

# of Collaborated Projects : 3results

# of Collaborated Products : 4results
20. WAKANA Shigeharu (90192434)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
21. KANAI Yoshiakira (30260326)

# of Collaborated Projects : 3results

# of Collaborated Products : 1results
22. HAYASHI Yoshihiro (90092303)

# of Collaborated Projects : 3results

# of Collaborated Products : 1results
23. 早川純一郎 (50110622)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
24. 豊田裕 (90050418)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
25. LI Hai

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
26. 王成懐

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
27. JIN Meilei

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
28. WANG Chenghuai

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
29. MAKI Kazushige (10311424)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
30. KANEDA Hideki (00214479)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
31. YASUI Fumihiko (40399473)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
32. NURIYA Hideko (80270685)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
33. KOHARA Kyoko (20225478)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
34. HIRANO Hiroyuki (00192716)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
35. TANO Shigemitsu (80011881)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
36. SANO Yoshio (70109528)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
37. MAEKAWA Masahiko (00142703)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
38. SAKAI Shunnosuke (90092783)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
39. MORIO Tomohiro (30239628)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
40. SORIMACHI Noriko (30217468)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
41. KANAI Masami (70321883)

# of Collaborated Projects : 2results

# of Collaborated Products : 1results
42. 浜岡利之 (60028529)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
43. 池田秀利 (60101119)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
44. 野村大成 (90089871)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
45. 小高健 (00012691)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
46. 高橋智 (50271896)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
47. KORABLEV V.

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
48. TSUCHIYA Masayuki

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
49. 邵啓全

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
50. 易豪雄

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
51. 凌定厚

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
52. 王斌

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
53. 何新橋

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
54. 呉政安

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
55. SHAO Qiquan

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
56. YI Haoziong

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
57. 王鳳山

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
58. 金攻蕾

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
59. TAMIO Ohno (90293620)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
60. HAYASHI Masahiro (70446566)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
61. SEKIGUCHI Satoshi (10462780)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
62. KOMATSU Masaaki (90356254)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
63. ONO Tomio (60231239)

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
64. YAMAGUCHI Midori (20593643)

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
65. IYAMA Shiya (00000232)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
66. OGATA Kazuo (40224092)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
67. SAKAIZUMI Mitsuru (40175360)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
68. MATSUI Masafumi (40101240)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
69. MORISHIMA Hiroko (70000247)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
70. ISHII Ai (80124436)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
71. MORIYAMA Kenji (00250217)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
72. SHIROKI Kazuko (40012744)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
73. TERADA Eiji (10113440)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
74. UMEDA Masato (10185069)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
75. ARAI Morio (00212605)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
76. TAI Tadashi (70112092)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
77. OKAMATO MIEKO (80152354)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
78. SATO Shingo (10143562)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
79. SHIGEAKI Nonoyama (40280961)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
80. YAMAGUCHI Yasunori (60191243)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
81. SATTA Yoko (20222010)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
82. FUJITA Takasi (10156870)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
83. TOYODA Tetsuya (00197972)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
84. YAZAKI Kazumori (20124498)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
85. NAGAO Yasumitsu (80303874)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
86. IMAI Hirosi (10303869)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
87. KOHNO KENJI (50142005)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
88. MATASUDA HIROSHI (80145820)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
89. Hori Masatoshi (70211547)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
90. 谷口克 (80110310)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
91. 山村研一 (90115197)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
92. 久保秀一 (00251223)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
93. 高野貴士 (20462781)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
94. 河野洋平 (20401383)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
95. 反町洋之 (10211327)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
96. 日合弘 (10073131)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
97. 山田淳三 (90025651)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
98. 高橋利忠 (00124529)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
99. 原田正史 (20117964)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
100. 小原良孝 (90003673)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
101. ISHIKAWA AKIRA (20211724)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
102. 永田喜三郎 (10291155)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
103. 北村ふじ子 (90124453)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
104. 倉持敏美 (90291153)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
105. 南直次郎 (30212236)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
106. 神沼修 (80342921)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
107. YAKIMENKO L.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
108. KANAI Noboru

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
109. KOIKE Morio

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
110. 王春燕

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
111. 李安生

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
112. 梁承業

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
113. 金玖〓

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
114. 施立明

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
115. 汪松

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
116. HE Xinqiao

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
117. SHI Liming

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
118. WANG Sung

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
119. WU Zheng-an

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
120. WANG Chun Yan

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
121. WANG Bin

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
122. LI An Sheng

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
123. LIANG Cheng Ye

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
124. QI Ding Hou

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
125. 金玖蕾

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
126. 王成懷

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
127. 孟筱崎

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
128. 王成壊

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
129. MENG Xiao qi

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
130. WR Zheng-an

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
131. SHUNNOSUKE Sakai

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
132. EANG Fengshan

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
133. 金〓蕾

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
134. 鮑世民

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
135. 寧磊

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
136. MENG Xiaoqi

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
137. WU Shaolin

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
138. AZIMOV Djaloliddin

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
139. AKBARZADEH Johangir

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
140. WANG Fenshan

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
141. YU Guode

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
142. KRYUKOV Alexei

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
143. GAIBOV N

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
144. AKBARZADEH J

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
145. KRUYKOV A

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
146. 于国徳

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
147. 孟筱くぃ

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
148. 呉祥林

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
149. 孟筱埼

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
150. 五十嵐浩二

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
151. 金井晃

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
152. 徳永智之

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
153. NAKADA Kazuto

# of Collaborated Projects : 0results

# of Collaborated Products : 6results
154. Kiyuna Tasuku

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
155. HIRAI Takahisa

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
156. ANDO Keiko

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
157. YOSHIDA Chiharu

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
158. MATSUO Isao

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
159. ABE Kuniya

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
160. SUGIMOTO Michihiko

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
161. YASAKA TAKU

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
162. SEKI Yuta

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
163. SUZUKI Sari

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
164. 小武家誠司

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
165. 當銘保則

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
166. 顧建国

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
167. 新田沙由梨

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
168. 池田和博

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
169. 織田公光

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
170. 芦原英司

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
171. 成瀬雅衣

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
172. 石田均

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
173. 北村大志

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
174. 上野博夫

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
175. 厚海奈穂

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
176. 東辻久子

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
177. 岡元邦彰

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
178. 筑波隆幸

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
179. 小島裕正

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
180. 中嶋弘一

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
181. 井上敏昭

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
182. 関山一成

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
183. 綿田裕孝

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
184. 安井正人

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
185. 吉田明雄

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
186. 久留一郎

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
187. 大内憲明

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
188. 権田幸祐

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
189. 谷口一郎

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
190. 島貫碧

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
191. 石川香

# of Collaborated Projects : 0results

# of Collaborated Products : 3results
192. 森晶夫

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
193. 佐伯真弓

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
194. 高田豊行

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
195. 日比野浩

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
196. 宮坂勇輝

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
197. 山西吉典

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

YONEKAWA Hiromichi 米川 博通

米川 博道

Research Projects

Research Products

Co-Researchers

Does age-associated down regulation of human SHMT2 and GCAT genes induce short lifespan or longevity?Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マウス発生過程における異質性mtDNA分離モデル構築と操作技術への応用Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of age-associated mitochondrial disorders caused by mtDNA or unknown cytoplasmic genetic elements found in mouse strainsOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

中枢神経系・感覚器における部位および伝達物質特異的神経細胞除去法の開発Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Generation and application of mouse models for neurodegenerative diseases by TRECK methodPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of gene manipulation for mammalian mitochondrial DNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Bioimaging of mitochondrial dynamics and generation of model micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

モデルマウスによるミトコンドリア病の治療原理とその開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

2種類のプロモーターで制御可能なTRECK法(DPD-TRECK法)の開発Principal Investigator

Principal Investigator

YONEKAWA Hiromichi 米川博通

米川博道