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yonekawa hiromichi  米川 博通

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YONEKAWA Hiromichi  米川 博通

米川 博道

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Researcher Number 30142110
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Affiliation (Current) 2022: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 研究員
2022: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 研究員
Affiliation (based on the past Project Information) *help 2021: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 研究員
2019 – 2020: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 研究員
2014 – 2019: 公益財団法人東京都医学総合研究所, 基盤技術研究センター, 特任研究員
2015: 公益財団法人東京都医学総合研究所, 客員研究員
2014: 公益財団法人東京都医学総合研究所, 遺伝子改変動物室, 特任研究員 … More
2013: 公益財団法人東京都医学総合研究所, 基盤技術研究センター, 研究員
2011: 東京都医学研究所, 基盤技術研究センター, センター長
2011: 東京都医学研究機構, 東京都臨床医学総合研究所, 副所長
2011: 財団法人東京都医学総合研究所, 基盤技術研究センター, センター長
2010: (財)東京都医学研究機構, 総合研究所, 参事研究員
2010: 東京都臨床医学総合研究所, 基盤技術センター, センター長
2005 – 2010: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 参事研究員
2009: (財)東京都医学研究機構, 研究員
2008 – 2009: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 副所長
2007 – 2008: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 参事研究員
2007: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 参事研究(副所長)
2007: (財)東京都医学研究機構, 東京都臨床学総合研究所, 研究員
2007: (財)東京都臨床医学総合研究所, 副所長
2007: Tokyo Metropolitan Institute of Medical Science, 東京都臨床医学研究所, Vice director
2007: 東京都臨床医学総合研究所, 参事研究員
2006: (財)東京都医学研究機構, 東京宇都臨床医学総合研究所, 参事研究員(副所長)
2006: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 研究員
2004 – 2006: TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH, THE TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE, Vice Director, 東京都臨床医学総合研究所, 参事研究員(副所長)
2003 – 2006: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 副所長
2005: Tokyo metropolitan institute of medical science, Vice director, 東京都臨床医学総合研究所, 副所長
2004: (財)東京医学研究機構, 東京都臨床医学総合研究所, 副所長
2004: 東京都医学研究機構, 東京都臨床医学研究所, 副所長
2004: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 参事研究員(副所長)
2003 – 2004: TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH, THE TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE, HEAD, 参事研究員
2003 – 2004: Tokyo Metropolitan Organization for Medical Research, The Tokyo Metropolitan Institute of Medical Science, Vice-director, 東京都臨床医学総合研究所, 副所長
2002 – 2004: 財)東京都医学研究機構, 実験動物研究部門, 副所長(研究職)
2003: (財)東京都医学研究機構, 参事研究員
2003: (財)東京都医学研究機構, 東京都臨床医学総合研究所・参事研究員, 副所長
2002 – 2003: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 参事研究員
2002: (財)東京医学研究機構, 東京都臨床医学総合研究所, 副所長
2002: 東京医科歯科大学, 大学院・医歯学総合研究科, 教授
2002: The Tokyo Metropolitan Institute of Medical Science, Vice-director, 実験動物研究部, 副所長(研究職)
2002: 財団法人 東京都医学研究機構, 東京都臨床医学総合研究所, 参事研究員(副所長)
2002: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 参事研究員(副所長)
2001: (財)東京都医学研究機関, 実験動物研究部門, 副所長(研究職)
2001: 財団法人 東京都医学研究機構, 東京都臨床医学総合研究所・研究員(副所長)
2001: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員〔副所長〕
2001: THE TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE, DEPARTMENT OF LABORATORY ANIMAL SCIENCE, ACTING HEAD(VICE DERECTOR OF THE INSTITUTE), 東京都臨床医学総合研究所・研究員(副所長)
2000 – 2001: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 副所長
2000 – 2001: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員
1999 – 2001: 東京都臨床医学総合研究所, 副所長
2000: The Tokyo Metropolitan Institute of Medical Science, Vice-Director, 実験動物研究部門, 副所長(研究職)
2000: 東京都・臨床医学総合研究所, 副所長
2000: The Tokyo Metropolitan Institute of Medical Science, Vice Director, 医科学研究所, 研究員
2000: 東京都臨床医学総合研究所, 実験動物研究部門, 部長(研究職)
1999 – 2000: Tokyo Metropolitan Organization for Medical Research, The Tokyo Metropolitan Institute of Medical Science, Vice-Director, 東京都臨床医学総合研究所, 副所長
1999 – 2000: 財団法人 東京都医学研究機構, 東京都臨床医学総合研究所, 副所長
1999: (財)東京都臨床医学総合研究所, 副所長(研究職)
1999: 財団法人 東京都医学研究機構, 東京都臨床医学総合研究所, 研究員
1998: (財)東京都臨床医学総合研究所, 動物実験研究部門, 研究員
1998: The Tokyo Metropolitan Institute of Medical Science, Department of Laboratory An, 実験動物研究部門, 研究員
1997 – 1998: (財)東京都臨床医学総合研究所, 実験動物研究部門, 研究員
1996 – 1998: 東京都臨床医学総合研究所, 実験動物研究部門, 部長
1995 – 1998: 財団法人東京都臨床医学総合研究所, 実験動物研究部門, 研究員
1997: Tokyo Metropol.Inst.Med.Sci.Exp.Animal Lab., Lab.Head, 実験動紡研究室, 部長
1996 – 1997: (財)東京都臨床医学総合研究所, 実験動物研究室, 部長
1995 – 1997: 東京都臨床医学総合研究所, 実験動物研究部門, 室長
1996: 東京都臨床医学総合研究所, 実験動物, 部長
1996: 東京都臨床医学総合研究所, 実験動物研究部門, 研究員
1995: 東京都臨床医学総合研究所, 実験動物研究室, 室長
1995: The Tokyo Metropolitan Institute of Medical Science Dept.of Laboratory animal sc, 実験動物研究部門, 研究員
1994: The Tokyo Metropolitan Institute of Medical Science, Department of Laboratory Animal Science, Investigator, 実験動物研究部門, 研究員
1994: 財団法人 東京都臨床医学総合研究所, 実験動物 研究部門, 研究員
1994: The Tokyo Metoropolitan Inst. of Medical Science, Lab.Head, 実験動物研究部, 室長
1993: 財団法人 東京都臨床医学総合研究所, 実験動物研究部門, 研究員
1993: 都臨床研究所, 実験動物研究部, 室長
1992: 都臨床医学総合研究所, 実験動物, 室長
1991 – 1992: Rinshoken, Exp. Ani. Sci., Chief, 実験動物, 室長
1991: The Tokyo Metropolitan Institute of Medical Science, Lab. Head, 実験動物部, 室長
1990 – 1991: 東京都臨床医学総合研究所, 実験動物部, 室長
1988 – 1991: 東京都臨床医学総合研究所, 実験動物研究部門, 室長
1986: 埼玉がんセンター研究所, 生化学部, 主任研究員 Less
Review Section/Research Field
Principal Investigator
Laboratory animal science / Laboratory animal science / Laboratory animal science / Otorhinolaryngology / 遺伝
Except Principal Investigator
Biological Sciences / Laboratory animal science / Immunology / Laboratory animal science / Virology … More / Laboratory animal science / 遺伝 / Basic veterinary science/Basic zootechnical science / General anatomy (including Histology/Embryology) / Experimental pathology / Food science / 遺伝学 / Cell biology / Biological pharmacy / Neurochemistry/Neuropharmacology / Applied animal science / Molecular biology / Basic veterinary science/Basic zootechnical science / Integrative animal science / Basic Section 42040:Laboratory animal science-related Less
Keywords
Principal Investigator
トランスジェニックマウス / マウス / 遺伝子改変マウス / ヒト疾患モデル / Cre / mtDNA / 毒素受容体 / ジフテリア毒素 / ヒト疾患モデルマウス / 遺伝子導入動物 … More / ミトコンドリアDNA / 標的細胞ノックアウト法 / TRECK法 / T細胞 / ミトコンドリア病 / 組織特異的プロモーター / 蛍光タンパク質 / Cre/loxPシステム / 蛍光蛋白質 / 蛍光蛋白 / ジフテリア毒素受容体 / 中枢神経系 / Transgenesis / アトピー性皮膚炎 / NC / Nga / MSM / 組織特異的プロモータ / 難聴 / コンジェニックマウス / 核・ミトコンドリア相互作用 / 突然変異 / mtGFP-Tgマウス / ホモ接合体 / ヘミ接合体 / リアルタイムPCR / ジンドーセージ / 簡易鑑定法 / 導入遺伝子コピー数 / 比較Ct法 / 実験動物学 / 系統維持 / SCIDマウス / ヒト細胞置換マウス / 肝実質細胞 / SCID-Huマウス / ヒト肝実質細胞 / HCV / 移植 / HSV-TK / ガンシクロビル / ヒト臍帯血 / 肝臓特異的プロモータ / CD4細胞 / CD8細胞 / 組換えBAC / BAC-トランスジェネシス / loxPシステム / Tgマウス / 二重制御系 / 細胞機能 / ミトコンドリア / バイオイメージング / 疾患モデル / 運動失調 / 疾患モデルマウス / コピー数 / 遺伝子治療 / Cre/loxP / 細胞特異的破壊法 / Recombineering / 遺伝子操作 / 人工ヌクレアーゼ / ミトコンドリア内局在型 / TALEN / ミトコンドリア局在型TALEN / モデルマウス / チロシナーゼ / トランスジェネシィス / Tyrosinase / Visible Marker / Transgene / Genotoxicity / Gene Manipulation / 酵母人工染色体 / 大腸菌人工染色体 / トランスジェネシス / 突然変異マウス / 遺伝子レスキュー / YAC / mice / YACs / BACs / in vivo gene rescue / C型肝炎ウィルス(HCV) / LoxP条件付発現 / ウィルス排除機構 / C型肝炎モデルマウス / C型肝炎ウイルス(HCV) / ウイルス排除機構 / C型肝炎 / 病理性発現機序 / 細胞障害性T細胞 / Hepatitis C Virus (HCV) / Transgenic mice / loxP conditional expression / Mechanism for viral exclusion / Animal Models / 野生マウス / ロシア / 中国 / mtDNA多型 / 核型解析 / ヘモグロビンβ鎖多型 / タイプ標本画像データ / 系統化 / 型解析 / 遺伝的多型 / 亜種分化 / ヘモグロビン / ネパール / カザフスタン / Wild mice / Russia / China / mtDNA polymorphism / Karyotype analysis / Hemoglobin β chain variants / specimen / Inbreeding / 高IgE血症 / ラディエーションハイブリッドパネル / 多因子連鎖解析 / マイクロサテライト / 近交系マウス / アトピー性疾患 / 遺伝子マッピング / 皮膚炎 / アレルギー / Model mouse for human diseases / Atopic dermatitis / Mice / Radiation hybrid panel / Linkage disequilibrium / Microsatellite / Ms / マスト細胞 / 細胞標的破壊法 / transgenic mice / atopic dermatitis (eczema) / mast cells / T cells / Diphtheria toxin / Diphtheria toxin receptor / Tissue specific promotor / conditional cell depletion / ノックインマウス / Cre/loxP系 / Dre/rox系 … More
Except Principal Investigator
野生マウス / ミトコンドリアDNA / C型肝炎ウイルス / Sox17 / トランスジェニックマウス / 持続感染 / X染色体 / マウス / 基準近交系マウス / 遺伝的特性検査 / 胚凍結保存 / 系統情報 / 遺伝子マッピング / インターフェロン / ミトコンドリア病 / Wild mouse / mouse / 内胚葉 / 腸管形成 / TL / 腫瘍発生抑制遺伝子 / mtDNA・Dル-プ / 自然免疫 / ミトコンドリア / 病態モデルマウス / 老化 / Mitochondrial DNA / シグナル伝達 / 修飾遺伝子 / Congenic系マウス / Recombinant Inbred系マウス / 微生物的特性検査 / Recombinant Inbred系統 / Hー2組換ホットスポット / コンジェニック系マウス / リコンビナント・インブレッド系マウス / 微生物特性検査 / リコンビナント・インブレッド系統 / T細胞レセプタ- / TL遺伝子 / C型肝炎ウィルス / 免疫抑制 / 免疫寛容 / 動物モデル / 感染性cDNAクローン / 遺伝子 / 肝がん / 持続感染複製 / WRN蛋白質 / p53蛋白質 / ジフテリア毒素 / ミトコンドリア遺伝子疾患 / 突然変異 / 老化関連疾患 / mtDNA / 日本産野生マウス / レトロポゾン / 地理的分布 / 野生イネ / Rice / Ribosomal DNA / Geographical distribution / リボソームDNA / HSP70 / ヘモグロビン / Subspecies group / IRES / transgenic mouse / プレB細胞レセプター / B細胞分化 / Igβ / signal transduction / Modifier gene / HCV / ノックアウトマウス / Endoderm / マウス先天性白内障 / IRF-3 / 自己免疫疾患 / congenital cataract / cataract mouse / rct gene / modifier gene / disease model mouse / Sox18 / Vcam-1 / 発生・分化 / endoderm / gut formation / 補体制御H蛋白 / Hー2組換えホットスポット / 組換えホットスポット / T細胞レセプター / レトロウイルス遺伝子 / リボソーム遺伝子 / アレルギー / アレルゲン / モデル動物 / IgE / 卵白アルブミン / アラフィラキシー / ダニ抗原 / アナフィラキシー / T細胞 / siRNA / 再構成ウイルス / ゲノム不安定化 / HCV遺伝子スイッチング発現 / Tgマウス / 発癌 / レプリコン細胞 / プロテオミクス解析 / ウイルス / 感染症 / 癌 / C型肝炎 / NCマウス / マラリア原虫 / 脳マラリア / マラリア腎症 / アトピー性皮膚炎 / 原因遺伝子群 / 好塩基球 / 相同組み換え / 緑色蛍光色素 / 系列特異的細胞消去 / 獲得免疫 / ミトコンドリアゲノム変異 / 突然変異型 mtDNA / 呼吸欠損 / 突然変異型mtDNA / 病態モデル / 病態モデルマス / モデルマウス / カルパイン / 胃 / 酵素 / 蛋白質 / プロテオリシス / カルシウム / ジフテリアトキシン / 表層粘液細胞 / ミトコンドリアゲノム / ミトコンドリア移植 / 哺乳類 / 生理的役割 / がん化 / がん / ヘテロプラズミー / ウレタン誘発染色体異常 / H-2複合遺伝子 / 紫外線感受性 / RI系統 / ウレタン誘発肺腫瘍 / 発癌感受性遺伝子 / ウイルス抑制因子 / フレンドウイルス抵抗性遺伝子 / env遺伝子DNA / 近交系ラット / H-2 / 腫瘍発生制御遺伝子 / RTI / 遺伝的組換ホットスポット / イネ / リボゾ-ムDNA / 遺伝的亜種分化 / ヒトの移動 / 中国大陸 / リボソ-ムDNA / 遺伝変異 / 進化 / 栽培化 / 遺伝変異(地理的変異) / 裁培化 / Genetic differentiation of subspecies / Human migration / Retroposon / 動物地理 / 種分化 / 集団遺伝学 / 分子進化 / 実験動物 / 日本産野生動物 / 遺伝学 / zoogeography / speciation / population genetics / molecular evolution / experimental animal / 低温抵抗性 / リボゾームDNA / 亜種群 / ヘモグロビンβ鎖 / 染色体Cバンド / 低温低抗性 / Gcnctic differentiation of subspeies / Human migraion / Subspccics group / 胸腺 / T細胞負の選択 / アポプトーシス / 疾患モデル / 胸線 / Transgenic mouse / Thymus / Negative selection of T cell / Apoptosis / Human disease-model mouse / 系統育成 / ヘモグロビン遺伝子 / W1型ヘモグロビン / cDNA塩基配列 / ロシア東部地域 / 中国東北部地域 / 中央アジア地域 / 野生マウス亜種 / ロシア東部 / ウズベキスタン / 野生系統育成 / 剥製標本 / 画像データベース / 遺伝的分化 / 中国 / 生物機能モデル系統 / 地理的分化 / Asia / China / Russia / Genetic distance / beta-hemoglobin genes / Hbb-w1 haplotype / intersubspecies recombinant / マウスmtDNA / ミトコンドリアノックアウト / 糖尿病 / mtDNA欠損細胞 / mtDNA導入 / トランスジェニックスマウス / インスリン分泌細胞 / Mouse mtDNA / Mutation / Mitochondria knockout / Mitochondrial diseases / Diabetes mellitus / Aging / ポリオウイルス受容体遺伝子 / 組織特異的発現 / ポリオウイルスレセプター遺伝子 / YACクローン / poliovirus receptor gene / tissue-specific expression / animal model / コンソミック / 戻し交配 / マイクロサテライト / コンソミック系統 / 連鎖解析 / 遺伝的多型 / マイクロサテライトマーカー / subspecies / chromosome / backcross / microsatellite / consomic / linkage / アポリポタンパク質 / 動脈硬化 / 高密度リポタンパク質 / 自己抗体 / 血栓 / 自己免疫 / 膠原病 / コレステロール / アポリポタンパク質A-I / 血栓性疾患 / apolipoprotein / atherosclerosis / high density lipoprotein / autoantibody / thrombosis / autoimmune disease / rheumatoid arthritis / cholesterol / 糖鎖 / 抗体 / 神経症 / monoclonal antibody / carbohydrate chain / ganglioside / auto-immune disease / neuropathy / プロB細胞 / プレB細胞 / 遺伝子クローニング / ラフト / 免疫グロブリン遺伝子再構成 / 胚型転写物 / 免疫グロプリン遺伝子再構成 / 急性リンパ性白血病 / per B cell receptor (preBCR) / B cell differentiation / pro B cell / pre B cell / gene cloning / raft / ヘモグロビン変異 / 遺伝的背景 / 亜種グループ / マイクロサテライトDNA / FISH分析 / マウス亜種グループ / 骨格形成遺伝子 / リボソーム蛋白遺伝子 / ヘモグロビン・ベータ・w1 / DNA塩基配列 / サテライトDNA / FISH / チトクロームb / Hemoglobin variants / Genetic background / Microsatellite DNA / FISH analysis / トランスフォーム / HCV cDNAクローン / infectious cDNA / pathogenesis / replication / 卵黄嚢 / 後腸 / Gene targeting / Gut tube formation / ES細胞 / 精子 / 生殖系列キメラ / 全能性 / 精子受精能 / キメラ形成能 / 同胞異種 / 胚性幹細胞 / ES cell / mitochondrial DNA / sperm / germ-line chimera / totipotency / マウス遺伝子のマッピング / rct遺伝子 / mrct遺伝子 / マウスBAC contig / 原因遺伝子座 / 修飾遺伝子座 / クローニング / Mouse ingerited cataract, / Interval mapping of mouse genes, / rct gene, / mrct gene, / ES / ES cells / Gut / Hepatitis C Virus / Interferon / Persistent infection / Dimer formation / μH鎖 / 代替軽鎖 / 品質管理 / 免疫不全症 / 遺伝子再構成 / 大型プレB細胞 / チロシンリン酸化 / NKκB / Srcファミリーキナーゼ / PKC / B cell development / pre B cell receptor / μH chain / surrogate light chain / quality check / immunodeficiency / autoimmune deseases / 白内障マウス / 白内障遺伝子 / 疾病モデルマウス / desease model mouse / mrct gene / modifier genes / cataract gene / ミトコンドリア遺伝病 / マウス突然変異型mtDNA / 核移植による遺伝子治療 / クローンマウス / ミトコンドリア遺伝子病 / 病態モデルマウス(ミトマウス) / 受精卵遺伝子治療 / ミトコンドリア間相互作用 / 臨床症状の多様性 / ミトコンリア間相互作用 / mitochondrial diseases / mouse mtDNA mutation / disease model mice / gene therapy by nuclear transplantation / clone mice / 血管形成 / 肝臓 / 腎臓 / 胚性内胚葉 / Sox07 / 欠陥形成 / angiogenesis / liver / kidney / gut endoderm / Sox17因子 / development / 生殖細胞 / 始原生殖細胞 / development and differentiation / germ cells / mtDNA突然変異 / ヒトがん転移 / ヒト老化の可逆的制御 / Shmt2遺伝子破壊マウス / 胚致死 / 1炭素代謝系 / がん転移 / ヒト老化の可逆性 / マウス内在性ウイルス / マウス細胞質遺伝子 / shmt2遺伝子破壊マウス / マウス細胞質遺伝因子 / ミトコンドリア老化原因説 / ミトコンドリアがん転移原因説 / マウスmtDNA突然変異 / 細胞質遺伝因子 / 内在性ウイルス / カハール介在細胞 / TRECKマウス / c-kit / ANO-1 / 消化管 / Cre/loxp / Ano-1 / 獣医学 / 生理学 / 再生医学 / 異質性 / 初期発生 / ヒト老化モデル / ミトコンドリア呼吸欠損 / Shmt2遺伝子 / Gcat遺伝子 / 一炭素代謝 / ヒト老化モデルマウス / 細胞分裂阻害 / Shmt2遺伝子・ Gcat遺伝子 / ヒト老化 / SHMT2遺伝子 / GCAT遺伝子 / ミトコンドリア 呼吸欠損 / Shmt2遺伝子とGcat遺伝子 / 細胞分化阻害 Less
  • Research Projects

    (68 results)
  • Research Products

    (79 results)
  • Co-Researchers

    (174 People)
  •  Does age-associated down regulation of human SHMT2 and GCAT genes induce short lifespan or longevity?

    • Principal Investigator
      Hayashi Jun-Ichi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      University of Tsukuba
  •  The segregation of heteroplasmic mtDNA during mouse development and its application to manipulation techniques

    • Principal Investigator
      SHITARA Hiroshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Investigation of age-associated mitochondrial disorders caused by mtDNA or unknown cytoplasmic genetic elements found in mouse strains

    • Principal Investigator
      HAYASHI Jun-Ichi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      University of Tsukuba
  •  Development of locus- and/or neurotransmitter-specific cell depletion method in CNS and/or sensory organsPrincipal Investigator

    • Principal Investigator
      YONEKAWA Hiromichi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Elucidation of regeneration mechanism of digestive tract pacemaker cell by modified TRECK method

    • Principal Investigator
      Hori Masatoshi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Integrative animal science
    • Research Institution
      The University of Tokyo
  •  Paradigm shift of mammalian mitochondrial genome using intercellular transfer technology

    • Principal Investigator
      HAYASHI Jun-Ichi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      University of Tsukuba
  •  Generation and application of mouse models for neurodegenerative diseases by TRECK methodPrincipal Investigator

    • Principal Investigator
      YONEKAWA Hiromichi
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Development of mouse models for heteroplasmic mitochondrial DNA transmission

    • Principal Investigator
      SHITARA Hiroshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Development of gene manipulation for mammalian mitochondrial DNAPrincipal Investigator

    • Principal Investigator
      YONEKAWA Hiromichi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Bioimaging of mitochondrial dynamics and generation of model micePrincipal Investigator

    • Principal Investigator
      YONEKAWA Hiromichi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      財団法人東京都医学総合研究所
      Tokyo Metropolitan Organization for Medical Research
  •  モデルマウスによるミトコンドリア病の治療原理とその開発Principal Investigator

    • Principal Investigator
      米川 博通
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Persistent infection of Hepatitis C virus to get over the acquired immunity system

    • Principal Investigator
      KOHARA Michinori
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Analysis of entire physiological roles of mammalian mtDNA by generation of mice carrying various pathogenic mutations

    • Principal Investigator
      HAYASHI Jun-ichi
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Laboratory animal science
    • Research Institution
      University of Tsukuba
  •  2種類のプロモーターで制御可能なTRECK法(DPD-TRECK法)の開発Principal Investigator

    • Principal Investigator
      米川 博通
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  胃カルパインの粘膜特異的発現を応用した粘液分泌機構解析と食品の粘膜保護機能検索

    • Principal Investigator
      反町 洋之
    • Project Period (FY)
      2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Food science
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  C型肝炎ウイルスによる遺伝子変異蓄積及び細胞不死化機序の解析

    • Principal Investigator
      小原 道法
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Trial of human tissue-substituted mice and its application to human diseases.Principal Investigator

    • Principal Investigator
      YONEKAWA Hiromichi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Analysis of Common Genetic Factors for Allergy and Infectious Disease in NC Mice

    • Principal Investigator
      TAMIO Ohno
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Nagoya University
  •  系列特異的細胞消去法を応用した免疫細胞の生体内機能解析

    • Principal Investigator
      烏山 一
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Tokyo Medical and Dental University
  •  Aberrant migration of primordial germ cells in the Sox 17^<-/-> mouse embryos

    • Principal Investigator
      KANAI Masami
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Kyorin University
  •  C型肝炎ウイルスによる遺伝子変異蓄積及び細胞不死化機序の解析

    • Principal Investigator
      小原 道法
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  トランスジェニックマウスにおける導入遺伝子コピー数の測定法の開発と応用Principal Investigator

    • Principal Investigator
      米川 博通
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  C型肝炎ウイルスによる自然免疫及び獲得免疫系修飾機序の解析とその制御

    • Principal Investigator
      小原 道法
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  The role of Sox 17 during mouse gut formation.

    • Principal Investigator
      KANAI Masami
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Kyorin University
  •  C型肝炎ウイルスの細胞および個体免疫系修飾による持続感染成立機序の解析とその制御

    • Principal Investigator
      小原 道法
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  C型肝炎ウイルスの持続複製による遺伝子不安定化と肝がん発症機序の解析とその制御

    • Principal Investigator
      小原 道法
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Redundant function of Sox17 and Sox18 in mouse angiogenesis

    • Principal Investigator
      KANAI Yoshiakira
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      The University of Tokyo
  •  C型肝炎ウィルスの細胞および個体免疫系修飾による持続感染成立機序の解析とその制御

    • Principal Investigator
      小原 道法
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Identification of cells or cell lineage responsible for atopic dermatitis-like skin lesions in model mice for human diseases by means of TRECK methodPrincipal Investigator

    • Principal Investigator
      YONEKAWA Hiromichi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH
  •  Impairment of the dimer formation of interferon regulatory factor-3 by hepatitis C virus core protein leads to evade interferon system

    • Principal Investigator
      KOHARA Michinori
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Dynamism of B cell development

    • Principal Investigator
      KARASUYAMA Hajime
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Tokyo Medical and Dental University
  •  ヒト先天性白内症モデルマウス、RCT,の原因遺伝子と修飾遺伝子の単離と機能解析

    • Principal Investigator
      MAEDA Yukiko
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      遺伝
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Application of disease-model mice with mutant mtDNA for precise investigation of its pathogenesis

    • Principal Investigator
      HAYASHI Jun-Ichi
    • Project Period (FY)
      2002 – 2006
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      University of Tsukuba
  •  C型肝炎ウィルスの細胞および個体免疫系修飾による持続感染成立機序の解析とその制御

    • Principal Investigator
      KOHARA Michinori
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  ミトコンドリア遺伝子の異常を伴うヒト遺伝性難聴に対するモデルマウスの作製とその解析Principal Investigator

    • Principal Investigator
      米川 博通
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  A cell-autonomous activity of mouse Sox17 gene in mouse embryogenesis

    • Principal Investigator
      KANAI Yoshiakira
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  Effect of different type of mitochondrial DNA on germline-differentiating potency of ES cell line in the mouse

    • Principal Investigator
      NAGAO Yasumitsu
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied animal science
    • Research Institution
      KYOTO UNIVERSITY
  •  Cloning of causative gene responsible for a new ingerited cataract in the mouse

    • Principal Investigator
      MAEDA Yukiko Y.
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Science
  •  慢性アレルギー疾患モデル動物の開発とアレルギー病態の解析

    • Principal Investigator
      KARASUYAMA Hajime
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Immunology
    • Research Institution
      Tokyo Medical and Dental University
      Tokyo Metropolitan Organization for Medical Research
  •  Characterization of HCV replication and pathogenesis in animal model

    • Principal Investigator
      KOHARA Michinori
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Virology
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  Functional analysis of mouse Sox17 gene by using the gene targeting method.

    • Principal Investigator
      KANAI Yoshiakira
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  Russia-Japan Cooperative Survey and Breeding of Wild MicePrincipal Investigator

    • Principal Investigator
      YONEKAWA Hiromichi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      遺伝
    • Research Institution
      Tokyo Organization for Medical Research, The Tokyo Metropolitan Institute of Medical Science
  •  TOWARD TO POSITIONAL CLONING OF HUMAN POLYGENIC DISEASES USING MOUSE MODELS WITH SPECIAL REFERENCE TO ATOPIC DERMATITISPrincipal Investigator

    • Principal Investigator
      YONEKAWA HIROMICHI
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH, THE TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE
  •  Study on B cell differentiation signaling by using a novel system

    • Principal Investigator
      KARASUYAMA Hajime
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Immunology
    • Research Institution
      Tokyo Medical and Dental University
      Tokyo Metropolitan Organization for Medical Research
  •  Evolutionary status of the genetic background in the wild mice and its participation in manifestation of the genes for biological functions in mouse models

    • Principal Investigator
      MORIWAKI Kazuo
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Laboratory animal science
    • Research Institution
      The Graduate University for Advanced Studies
  •  Establishment of laboratory transgenic mouse strains for hepatitis C virus infectionPrincipal Investigator

    • Principal Investigator
      YONEKAWA Hiromichi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Generation of model mice for auto immune neuropathy by transfection with anti-carbohydrate chain antibody genes.

    • Principal Investigator
      TAI Tadashi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Animal model of autoimmune-induced atherosclerosis : Clinical significance of autoantibody against apolipoprotein A-I

    • Principal Investigator
      UMEDA Masato
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  Cino-Japanese cooperative research on surveying genetic variants in Chinese wild mice and developing their inbred strains

    • Principal Investigator
      MORIWAKI Kazuo
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      遺伝
    • Research Institution
      The Graduate University for Advanced Studies
  •  Analyzes of genes responsible for aging and the pathogenesis of diabetes by isolation of transgenic mice with pathogenic mtDNA mutation

    • Principal Investigator
      HAYASHI Jun-ichi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      University of Tsukuba
  •  Establishement of in vivo Rescue Techniques for Mutant Genes by YAC-TransgenesisPrincipal Investigator

    • Principal Investigator
      YONEKAWA Hiromichi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  Development of transgenic mice susceptible to orally-inoculated poliovirus

    • Principal Investigator
      SHIROKI Kazuko
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Virology
    • Research Institution
      The University of Tokyo
  •  Establishment of Mouse Consomic Lines

    • Principal Investigator
      SHIROISHI Toshihiko
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      National Institute of Genetics
  •  Analysis of transgenic mice expressing human HSP70

    • Principal Investigator
      ISHII Ai
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  Establishment of Transgene Detection System with Mouse Tyrosinase Gene as a Visible Reporter GenePrincipal Investigator

    • Principal Investigator
      YONEKAWA Hiromichi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  野生遺伝子の導入による生物機能モデル動物の開発

    • Principal Investigator
      森脇 和郎
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Institute of Genetics
  •  Sino-Japnese cooperative studies on the genetic differentiation of Wild mice and rice.

    • Principal Investigator
      MORIWAKI Kazuo
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Fukuyama University
      National Institute of Genetics
  •  がん研究のための実験動物の維持と開発

    • Principal Investigator
      森脇 和郎
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Institute of Genetics
  •  野生遺伝子の導入による生物機能モデル動物の開発

    • Principal Investigator
      森脇 和郎
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Institute of Genetics
  •  がん研究のための実験動物の維持と開発

    • Principal Investigator
      森脇 和郎
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Institute of Genetics
  •  野生遺伝子の導入による生物機能モデル動物の開発

    • Principal Investigator
      森脇 和郎
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Institute of Genetics
  •  がん研究のための実験動物の維持と開発

    • Principal Investigator
      MORIWAKI Kazuo
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Institute of Genetics
  •  野生遺伝子の導入による生物機能モデル動物の開発

    • Principal Investigator
      森脇 和郎
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Institute of Genetics
  •  Sino-Japanese cooperative studies on the genetics differentiation in the plants and animal in China

    • Principal Investigator
      MORIWAKI Kazuo
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      National Institute of Genetics
  •  Molecular Population Genetics of Japanese Wild Animal Species

    • Principal Investigator
      MORIWAKI Kazuo
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      遺伝学
    • Research Institution
      National Institute of Genetics
  •  がん研究のための実験動物の維持と開発

    • Principal Investigator
      森脇 和郎
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Institute of Genetics
  •  野生遺伝子の導入による生物機能モデル動物の開発

    • Principal Investigator
      森脇 和郎
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Institute of Genetics
  •  哺乳動物による発癌制御の遺伝機構に関する研究

    • Principal Investigator
      森脇 和郎
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Institute of Genetics

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2003 Other

All Journal Article Presentation Book

  • [Book] 生物機能モデルと新しいリソース・リサーチツール2011

    • Author(s)
      米川博通(編集)
    • Total Pages
      671
    • Publisher
      Life-Science Information Center(LIC)
    • Data Source
      KAKENHI-PROJECT-21240044
  • [Book] 生物機能モデルと新しいリソース・リサーチツール2011

    • Author(s)
      米川博通(編集)
    • Total Pages
      671
    • Publisher
      Life-Science Information Center(LIC)
    • Data Source
      KAKENHI-PROJECT-21650102
  • [Book] Mouse Lab Manual (in Japanese)2003

    • Author(s)
      Yonekawa, H. et al. ed.
    • Total Pages
      376
    • Publisher
      Springer Verlag Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14208098
  • [Journal Article] OHC-TRECK: A Novel System Using a Mouse Model for Investigation of the Molecular Mechanisms Associated with Outer Hair Cell Death in the Inner Ear2019

    • Author(s)
      Matsuoka Kunie、Wada Kenta、Miyasaka Yuki、Yasuda Shumpei P.、Seki Yuta、Nishito Yasumasa、Yonekawa Hiromichi、Taya Choji、Shitara Hiroshi、Kikkawa Yoshiaki
    • Journal Title

      Scientific Reports

      Volume: 9: 5285

    • DOI

      10.1038/s41598-019-41711-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H04688
  • [Journal Article] Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal2018

    • Author(s)
      Tani H, Ohnishi S, Shitara H, Mito T, Yamaguchi M, Yonekawa H, Hashizume O, Ishikawa K, Nakada K, Hayashi JI.
    • Journal Title

      Sci. Rep.

      Volume: 8 Pages: 425-425

    • DOI

      10.1038/s41598-017-18828-3

    • NAID

      120007134501

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K18535, KAKENHI-PROJECT-16K19034, KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-16K14719, KAKENHI-PROJECT-18K06203, KAKENHI-PROJECT-16H02463, KAKENHI-PROJECT-16H04688, KAKENHI-PROJECT-18J20289
  • [Journal Article] Skin CD4+ Memory T Cells Play an Essential Role in Acquired Anti-Tick Immunity through Interleukin-3-Mediated Basophil Recruitment to Tick-Feeding Sites2017

    • Author(s)
      Ohta Takuya、Yoshikawa Soichiro、Tabakawa Yuya、Yamaji Kayoko、Ishiwata Kenji、Shitara Hiroshi、Taya Choji、Oh-hora Masatsugu、Kawano Yohei、Miyake Kensuke、Yamanishi Yoshinori、Yonekawa Hiromichi、Watanabe Naohiro、Kanuka Hirotaka、Karasuyama Hajime
    • Journal Title

      Front Immunol

      Volume: 8 Pages: 1348-1348

    • DOI

      10.3389/fimmu.2017.01348

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15719, KAKENHI-PROJECT-15H05786, KAKENHI-PROJECT-16H04688, KAKENHI-PROJECT-15K20969
  • [Journal Article] Establishment of a heteroplasmic mouse strain with interspecific mitochondrial DNA haplotypes and improvement of a PCR-RFLP-based measurement system for estimation of mitochondrial DNA heteroplasmy.2017

    • Author(s)
      H. Shitara, L. Cao, M. Yamaguchi, H. Yonekawa、C. Taya
    • Journal Title

      Transgenic Research

      Volume: 26 Pages: 559-565

    • DOI

      10.1007/s11248-017-0009-2

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25290038, KAKENHI-PROJECT-24228005, KAKENHI-PROJECT-16H04688
  • [Journal Article] Essential contribution of T cells to antigen-induced nasal hyperresponsiveness in experimental allergic rhinitis.2016

    • Author(s)
      Nishimura, T., Kaminuma, O., Saeki, M., Kitamura, N., Matsuoka, K., Yoneyama, H., Mori, A., and Hiroi, T.
    • Journal Title

      PLoS ONE

      Volume: 11

    • DOI

      10.1371/journal.pone.0146686

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461497, KAKENHI-PROJECT-26860122, KAKENHI-PROJECT-16H04688, KAKENHI-PROJECT-25290038
  • [Journal Article] Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation in Cdh23.2016

    • Author(s)
      Miyasaka Y, Shitara H, Suzuki S, Yoshimoto S, Seki Y, Ohshiba Y, Okumura K, Taya C, Tokano H, Kitamura K, Takada T, Hibino H, Shiroishi T, Kominami R, Yonekawa H, Kikkawa Y
    • Journal Title

      Human Molecular Genetics

      Volume: 印刷中 Pages: 2045-2059

    • DOI

      10.1093/hmg/ddw078

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-14J06119, KAKENHI-PROJECT-25430097, KAKENHI-PROJECT-25293058, KAKENHI-PROJECT-15H04291, KAKENHI-PROJECT-16H04688, KAKENHI-PROJECT-25290038, KAKENHI-PROJECT-15K18393
  • [Journal Article] G7731A mutation in mouse mitochondrial tRNA(Lys) regulates late-onset disorders in transmitochondrial mice.2015

    • Author(s)
      Shimizu A, Mito T, Hashizume O, Yonekawa H, Ishikawa K, Nakada K, Hayashi J.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 459 Pages: 66-70

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25290038
  • [Journal Article] G7731A mutation in mouse mitochondrial tRNALys regulates late-onset disorders in transmitochondrial mice2015

    • Author(s)
      Shimizu A, Mito T, Hashizume O, Yonekawa H, Ishikawa K, Nakada K, Hayashi J-I
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 459 Pages: 66-70

    • DOI

      10.1016/j.bbrc.2015.02.070

    • NAID

      120007130287

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J00467, KAKENHI-PLANNED-23117005, KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-25640057, KAKENHI-PROJECT-25290038
  • [Journal Article] A mouse somatic mutation orthologous to a MELAS A3302G mutation in the mitochondrial tRNALeu(UUR) gene confers the respiration defects.2015

    • Author(s)
      Shimizu A, Enoki S, Ishikawa K, Mito T, Obata K, Nagashima R, Yonekawa H, Nakada K, Hayashi J.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 467 Pages: 1097-102

    • DOI

      10.1016/j.bbrc.2015.09.072

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23117005, KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-14J00467, KAKENHI-PROJECT-25290038
  • [Journal Article] Administration of an antioxidant prevents lymphoma development in transmitochondrial mice overproducing reactive oxygen species.2014

    • Author(s)
      Yamanashi H, Hashizume O, Yonekawa H, Nakada K, Hayashi J.
    • Journal Title

      Exp Anim.

      Volume: 63(4) Pages: 459-466

    • NAID

      130004701643

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25640057
  • [Journal Article] Administration of an Antioxidant Prevents Lymphoma Development in Transmitochondrial Mice Overproducing Reactive Oxygen Species2014

    • Author(s)
      Yamanashi H, Hashizume O, Yonekawa H, Nakada K, Hayashi J.
    • Journal Title

      Experimental Animals

      Volume: 63 Issue: 4 Pages: 459-466

    • DOI

      10.1538/expanim.14-0038

    • NAID

      130004701643

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25250011
  • [Journal Article] Administration of an antioxidant prevents lymphoma development in transmitochondrial mice overproducing reactive oxygen species.2014

    • Author(s)
      Yamanashi H, Hashizume O, Yonekawa H, Nakada K, Hayashi J.
    • Journal Title

      Exp Anim.

      Volume: 63 Pages: 459-466

    • NAID

      130004701643

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25290038
  • [Journal Article] Generation of mouse models for type 1 diabetes by selective depletion of pancreatic beta cells using toxin receptor-mediated cell knockout2013

    • Author(s)
      K. Matsuoka, M. Saito, K. Shibata, M. Sekine, H. Shitara, C. Taya, Z. Zhang, T. Takahashi, K. Kohno, Y. Kikkawa & H. Yonekawa
    • Journal Title

      Biochem Biophys. Res. Commun.

      Volume: 436 Pages: 400-405

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25290038
  • [Journal Article] Novel Basophil- or Eosinophil-Depleted Mouse Models for Functional Analyses of Allergic Inflammation2013

    • Author(s)
      Matsuoka K, Shitara H, Taya C, Kohno K, Kikkawa Y, Yonekawa H.
    • Journal Title

      PlosOne

      Volume: 8

    • DOI

      10.1371/journal.pone.0060958

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24228005, KAKENHI-PROJECT-25290038
  • [Journal Article] Comprehensive application of an mtDsRed2-Tg mouse strain for mitochondrial imaging.2012

    • Author(s)
      Yamaguchi, J., Nishiyama, S., Shimanuki, M., Ono, T., Sato, A., Nakada, K., Hayashi, J-I., Yonekawa, H., Shitara, H
    • Journal Title

      Transgenic Res

      Volume: 21巻 Pages: 439447-439447

    • DOI

      10.1007/s11248-011-9539-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21240044, KAKENHI-PROJECT-22650091, KAKENHI-PROJECT-22680035, KAKENHI-PROJECT-24700442
  • [Journal Article] Global imaging of mitochondrial morphology in tissues using transgenic mice expressing mitochondrially targeted enhanced green fluorescent protein2010

    • Author(s)
      Hiroshi Shitara, Midori Shimanuki, Jun-Ichi Hayashi, Hiromichi Yonekawa
    • Journal Title

      Exp. Anim. 59

      Pages: 99-103

    • NAID

      10027852751

    • Data Source
      KAKENHI-PROJECT-19100007
  • [Journal Article] Global imaging of mitochondrial morphology in tissues using transgenic mice expressing mitochondrially targeted enhanced green fluorescent protein2010

    • Author(s)
      Shitara, H., Shimanuki, M., Hayashi, J-I., Yonekawa, H
    • Journal Title

      Experimental Animals

      Volume: 59巻 Pages: 99-103

    • NAID

      10027852751

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20224174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21240044
  • [Journal Article] Generation of trans-mitochondrial mito-mice by the introduction of a pathogenic G13997A mtDNA from highly metastatic lung carcinoma cells.2010

    • Author(s)
      Yokota, M., Shitara, H., Hashizume, O., Ishikawa, K., Nakada, K., Ishii, R., Taya, C., Takenaga, K., Yonekawa, H., Hayashi, J
    • Journal Title

      FEBS Lett

      Volume: 584巻 Pages: 3943-3948

    • DOI

      10.1016/j.febslet.2010.07.048

    • NAID

      120007137913

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21240044, KAKENHI-PROJECT-22650091, KAKENHI-PROJECT-22680035
  • [Journal Article] Over-expression of Tfam improves the mitochondrial disease phenotypes in a mouse model system2010

    • Author(s)
      Nishiyama, S., Shitara, H., Nakada, K., Ono, T., Sato, A., Suzuki, H., Ogawa, T., Masaki, H., Hayashi, J-I., Yonekawa, H
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 401巻 Pages: 26-31

    • DOI

      10.1016/j.bbrc.2010.08.143

    • NAID

      120007137866

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21240044, KAKENHI-PROJECT-22650091, KAKENHI-PROJECT-22680035
  • [Journal Article] Generation of trans-mitochondrial mito-mice by the introduction of a pathogenic G13997A mtDNA from highly metastatic lung carcinoma cells2010

    • Author(s)
      Mutsumi Yokota, Hiroshi Shitara, Osamu Hashizume, Kaori Ishikawa, Kazuto Nakada, Rie Ishii, Choji Taya, Keizo Takenaga, Hiromichi Yonekawa, and Jun-Ichi Hayashi
    • Journal Title

      FEBS Lett

      Volume: 84 Pages: 3943-3948

    • NAID

      120007137913

    • URL

      https://www.tulips.tsukuba.ac.jp/dspace/handle/2241/106654

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19100007
  • [Journal Article] The innate immune system in host mice targets cells with allogenic mitochondrial DNA2010

    • Author(s)
      Kaori Ishikawa, Noriko Toyama-Sorimachi, Kazuto Nakada, Mami Morimoto, Hirotake Imanishi, Mariko Yoshizaki, Shigemi Sasawatari, Mamoru Niikura, Keizo Takenaga, Hiromichi Yonekawa, and Jun-Ichi Hayashi
    • Journal Title

      J Exp. Med

      Volume: 207 Pages: 2297-2305

    • NAID

      120007137786

    • URL

      https://www.tulips.tsukuba.ac.jp/dspace/handle/2241/107854

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19100007
  • [Journal Article] Disruption of IFN Signaling and HCV Synergistically Enhance Lymphoproliferation through Type II CD95 and Interleukins2009

    • Author(s)
      Keigo Machida, Kyoko Tsukiyama-Kohara,Eiji Seike, ShigenobuTone, Yukiko Hayashi, Yuri Kasama, Masumi Shimizu, Hidemi Takahashi, Chyoji Taya, Hiromichi Yonekawa, Nobuyuki Tanaka, and Michinori Kohara
    • Journal Title

      Gastroenterology

    • Data Source
      KAKENHI-PROJECT-19041077
  • [Journal Article] New evidence confirms that the mitochondrial bottleneck is generated without reduction of mitochondrial DNA content in early peimordial germ cells of mice2009

    • Author(s)
      Liqin Cao, Hiroshi Shitara, Michihiko Sugimoto, Kuniya Abe, Jun-Ichi Hayashi, Hiromichi Yonekawa
    • Journal Title

      PLoS Genet 5

    • Data Source
      KAKENHI-PROJECT-19100007
  • [Journal Article] Disruption of IFN Signaling and HCV Synergistically Enhance Lympho proliferation through Type II CD95 and Interleukins2009

    • Author(s)
      K. Machida, H. Yonekawa, M. Kohara, et al.
    • Journal Title

      Gastroenterology (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18200028
  • [Journal Article] New evidence confirms that the mitochondrial bottleneck is generated without reduction of mitochondrial DNA content in early primordial germ cells of mice2009

    • Author(s)
      Cao, L., Shitara, H., Sugimoto, M., Hayashi, J.=I., Abe, K., Yonekawa, H.
    • Journal Title

      PLoS genetics

      Volume: Vol5

    • DOI

      10.1371/journal.pgen.1000756

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062013, KAKENHI-PROJECT-21240044
  • [Journal Article] Disruption of IFN Signaling and HCV Synergistically Enhance Lympho- proliferation through Type II CD95 and Interleukins.2009

    • Author(s)
      K. Machida, K. Tsukiyama-Kohara, E. Seike, S. Tone, Y. Hayashi, Y. Kasama, M. Shimizu, H. Takahashi, C. Taya, H. Yonekawa, N. Tanaka, M. Kohara.
    • Journal Title

      Gastroenterology in press

      Pages: 0-0

    • Data Source
      KAKENHI-PROJECT-18200028
  • [Journal Article] The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells2007

    • Author(s)
      Cao L, Shitara H, Horii T, Nagao Y, Imai I, Abe K, Hara T, Hayashi JI, Yonekawa H
    • Journal Title

      Nature Genetis 39

      Pages: 386-390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19100007
  • [Journal Article] The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells.2007

    • Author(s)
      Cao L, Shitara H, Horii T, Nagao Y, Imai H, Abe K, Hara T, Hayashi J, Yonekawa H.
    • Journal Title

      Nat Gent. 39(3)

      Pages: 386-90

    • Data Source
      KAKENHI-PROJECT-14GS0305
  • [Journal Article] The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells2007

    • Author(s)
      Liqin Cao, Hiroshi Shitara, Takuro Horii, Yasumitsu Nagao, Hiroshi Imai, Kuniya Abe, Takahiko Hara, Jun-Ichi Hayashi, and Hiromichi Yonekawa
    • Journal Title

      Nat. Genet

      Volume: 39 Pages: 386-390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19100007
  • [Journal Article] Deletion-mutant mtDNA increases in somatic tissues but decreases in female germ cells with age2007

    • Author(s)
      Akitsugu Sato, Kazuto Nakada, Hiroshi Shitara, Atsuko Kasahara, Hitomichi Yonekawa, and Jun-Ichi Hayashi
    • Journal Title

      Geneics

      Volume: 177 Pages: 2031-2037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19100007
  • [Journal Article] Deletion-mutant mtDNA increases in somatic tissues but decreases in female germcells with age2007

    • Author(s)
      Akitsugu Sato, Kazuto Nakada, Hiroshi Shitara, Atsuko Kasahara, Hiromichi Yonekawa, Jun-Ichi Hayashi
    • Journal Title

      Genetics 177

      Pages: 2031-2037

    • Data Source
      KAKENHI-PROJECT-19100007
  • [Journal Article] The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells.2007

    • Author(s)
      Cao L, Shitara H, Horii T, Nagao Y, Imai H, Abe K, Hara T, Hayashi J, Yonekawa H.
    • Journal Title

      Nat Genet. 39(3)

      Pages: 386-90

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14GS0305
  • [Journal Article] The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells2007

    • Author(s)
      Cao L, Shitara H, Horii T, Nagao Y, Imai H, Abe K, Hara T, Hayashi J, Yonekawa H.
    • Journal Title

      Nat Genet 39(3)

      Pages: 386-90

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14GS0305
  • [Journal Article] Mitochondria-related male infertility2006

    • Author(s)
      Nakada K, Sato A, Yoshida K, Morita T, Tanaka H, Inoue S, Yonekawa H, Hayashi J.
    • Journal Title

      Proc Natl Acad Sci U S A. 103(41)

      Pages: 15148-53

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14GS0305
  • [Journal Article] Mitochondria-related male infertility.2006

    • Author(s)
      Nakada K, Sato A, Yoshida K, Morita T, Tanaka H, Inoue S, Yonekawa H, Hayashi J.
    • Journal Title

      Proc Natl Acad Sci U S A. 103(41)

      Pages: 15148-53

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14GS0305
  • [Journal Article] Origins of mouse inbred strains deduced from whole-genome scanning by polymorphic microsatellite loci2005

    • Author(s)
      Sakai, T., KikKawa, Y., Miura, I., Inoue, I., Moriwaki, K., Shiroishi, T., Satta, Y., Takahata, N., Yonekawa, H
    • Journal Title

      Mamm. Genome 16

      Pages: 11-19

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14208098
  • [Journal Article] Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type Iα.2005

    • Author(s)
      Sasaki, J., Sasaki, T., Yamazaki, M., Matsuoka, M., Taya, C., Shitara, H., Takasuga, S., Nishio, M., Mizuno, K., Wada, T., Miyazaki, H., Watanabe, H., Iizuka, R., Kubo, S., Murata, S., Chiba, T., Maehama, T., Hamada, K., Kishimoto, H., Frohman, M.A., Tanaka, K., Penninger, J.M., Yonekawa, H., Suzuki, A., Kanaho, Y.
    • Journal Title

      J.Exp.Med. 201

      Pages: 859-870

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14208098
  • [Journal Article] Origins of mouse inbred strains deduced from whole-genome scanning by polymorphic microsatellite loci.2005

    • Author(s)
      Sakai, T., Kikkawa, Y., Miura, I., Inoue, T., Moriwaki, K., Shiroishi, T., Satta, Y., Takahata, N., Yonekawa, H.
    • Journal Title

      Mamm.Genome 16

      Pages: 11-19

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14540570
  • [Journal Article] Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation2005

    • Author(s)
      Sato A, Kono T, Nakada K, Ishikawa K, Inoue S, Yonekawa H, Hayashi J.
    • Journal Title

      Proc Natl Acad Sci U S A. 102(46)

      Pages: 16765-70

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14GS0305
  • [Journal Article] Rare creation of recombinant mtDNA haplotypes in mammalian tissues2005

    • Author(s)
      Sato A, Nakada K, Akimoto M, Ishikawa K, Ono T, Shitara H, Yonekawa H, Hayashi J.
    • Journal Title

      Proc Natl Acad Sci U S A. 102(17)

      Pages: 6057-62

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14GS0305
  • [Journal Article] Rare creation of recombinant mtDNA haplotypes in mammalian tissues.2005

    • Author(s)
      Sato A, Nakada K, Akimoto M, Ishikawa K, Ono T, Shitara H, Yonekawa H, Hayashi J.
    • Journal Title

      Proc Natl Acad Sci U S A. 102(17)

      Pages: 6057-62

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14GS0305
  • [Journal Article] Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation.2005

    • Author(s)
      Sato A, Kono T, Nakada K, Ishikawa K, Inoue S, Yonekawa H, Hayashi J.
    • Journal Title

      Proc Natl Acad Sci U S A. 102(46)

      Pages: 16765-70

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14GS0305
  • [Journal Article] Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α. ハ2005

    • Author(s)
      Sasaki, J., Sasaki, T., Yamazaki, M., Matsuoka, M., Taya, C., Shitara, H., Takasuga, S., Nishino, M., Mizuno, K., Wada, T., Miyazai, H., Watanabe, H., Iizuka, R., Kubo, S., Murata, S, Chiba, T., Maehama, T., Hamad, K., Kishimoto, H., Frohman, M.A., Tanaka, K., Penninger, J.M., Yonekawa, H., Suzuki, A., Kanaho, Y.
    • Journal Title

      J. Exp. Med. 201

      Pages: 859-870

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14208098
  • [Journal Article] PCRの功罪 -親子鑑定、化石、そしてジュラシックパーク2005

    • Author(s)
      米川博通
    • Journal Title

      蛋白質核酸酵素「2005年11月増刊:二層膜オルガネラの遺伝学」(林純一他 編集) 50・14

      Pages: 1912-1916

    • Data Source
      KAKENHI-PROJECT-17650123
  • [Journal Article] Influence on spatiotemporal patterns of a male-specific Sox9 activation by ectopic Sry Expression during early phases of testis differentiation in mice.2005

    • Author(s)
      Kidokoro, T., Matoba S., Hiramatsu, R., Fujisawa, M., Kanai-Azuma, M., Taya, C., Kurohmaru, M., Kawakami, H., Hayashi, Y., Kanai Y., Yonekawa, H.
    • Journal Title

      Dev.Biol. 278

      Pages: 511-525

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15580254
  • [Journal Article] Origins of mouse inbred strains deduced from whole-genome scanning by polymorphic microsatellite loci.2005

    • Author(s)
      Sakai, T., Kikkawa, Y., Miura, I., Inoue, T., Moriwaki, K., Shiroishi, T., Satta, Y., Takahata, N., Yonekawa, H.
    • Journal Title

      Mamm.Genome 16

      Pages: 11-19

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14208098
  • [Journal Article] Influence on spatiotemporal patterns of a male-specific Sox9 activation by ectopic Sry expression during early phases of testis differentiation in mice.2005

    • Author(s)
      Kidokoro T., Matoba S., Hiramatsu R., Fujisawa M., Kanai-Azuma M, Taya C., Kurohmaru M., Kawakami H., Hayashi Y., Kanai Y., Yonekawa H.
    • Journal Title

      Dev Biol. 278

      Pages: 511-525

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590152
  • [Journal Article] Origins of mouse inbred strains deduced from whole-genome scanning by polymorphic microsatellite loci.2005

    • Author(s)
      Sakai, T., Kikkawa, Y., Miura, I., Inoue, T., Moriwaki, K., Shiroishi, T., Satta, Y., Takahata, N., Yonekawa, H.
    • Journal Title

      Mamm. Genome 16

      Pages: 11-19

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14540570
  • [Journal Article] Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protem that associates with the USHIC protein, harmonin.2003

    • Author(s)
      Weil.D, El-Amraoui A, Masmoudi S, Mustapha M, Kikkawa Y, Zina ZB, Hamel C, Gal A, Ayadi H, Yonekawa H, Petit C
    • Journal Title

      Hum Mol Genet. 12

      Pages: 463-471

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14540570
  • [Journal Article] Long-term maintenance of IgE-mediated memory in mast cells in the absence of detectable serum IgE2003

    • Author(s)
      Kubo, S., Nakayama, T., Matsuoka, K., Yonekawa, H., Karasuyama, H
    • Journal Title

      J. Immunol. 170

      Pages: 775-780

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14208098
  • [Journal Article] A small deletion hotspot in the type II keratin gene mK6irs1/Krt2-6g on mouse chromosome 15, a candidate for causing the wavy hair of the caracul (Ca) mutation.2003

    • Author(s)
      Kikkawa, Y., Oyama, A., Ishii, R., Miura, I., Amano, T., Ishii, R, Yoshikawa, Y., Masuya, H., Wakana, S., Shiroishi, T., Taya, C., Yonekawa, H.
    • Journal Title

      Genetics 165

      Pages: 721-733

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14540570
  • [Journal Article] Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin.2003

    • Author(s)
      Weil, D., El-Amraoui, A., Masmoudi, S., Mustapha, M., Kikkawa, Y., Laine, S., Delmaghani, S., Adato, A., Nadifi, S., Zina, Z.B., Hamel, C., Gal, A., Ayadi, H., Yonekawa, H., Petit, C.
    • Journal Title

      Hum.Mol.Genet. 12

      Pages: 463-471

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14540570
  • [Journal Article] A small deletion hotspot in the type II keratin gene mK6irs1/Krt2-6g on mouse chromosome 15, a candidate for causing the wavy hair of the caracul (Ca) mutation.2003

    • Author(s)
      Kikkawa Y, Oyama A, Ishii R, Miura I, Amano T, Ishii Y, Yoshiwaka Y, Masuya H, Wakana S, Shiroishi T, Taya C, Yonekawa H.
    • Journal Title

      Genetics 165

      Pages: 721-733

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14540570
  • [Journal Article] Mutations in a new scaffold protein Sans cause deafness in Jackson shaker mice.2003

    • Author(s)
      Kikkawa, Y., Shitara, H., Wakana, S., Kohara, Y., Takada, T., Okamoto, M., Taya, C., Kamiya, K., Yoshikawa, Y., Tokano, H., Kitamura, K., Shimizu, K., Wakabayashi, Y., Shiroishi, T., Kominami, R., Yonekawa, H.
    • Journal Title

      Hum.Mol.Genet. 12

      Pages: 453-461

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14540570
  • [Journal Article] Long-term maintenance of IgE-mediated memory in mast cells in the absence of detectable serum IgE.2003

    • Author(s)
      Kubo, S., Nakayama, T., Matsuoka, K., Yonekawa, H., Karasuyama, H.
    • Journal Title

      J.Immunol. 170

      Pages: 775-780

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14208098
  • [Journal Article] Mutations in a new scaffole protein Sans cause deafness in Jackson shaker mice.2003

    • Author(s)
      Kikkawa Y, Shitara H, Wakana S, Kohara Y, Takada T, Okamoto M, Taya C, Kamiya K, Yoshikawa Y, Tokano H, Kitamura K, Shimizu K, Wakabayashi Y, Shiroishi T, Kominami R, Yonekawa H.
    • Journal Title

      Hum Mol Genet. 12

      Pages: 453-461

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14540570
  • [Journal Article] Mitochondrial physiology and gene expression analyses reveal metabolic and translational dysregulation in oocyte-induced somatic nuclear reprogramming

    • Author(s)
      Esteves, T. C., Psathaki, O. E., Pfeiffer, M. J., Balbach, S. T., Zeuschner, D., Shitara, H., Yonekawa, H., Siatkowski, M., Fuellen, G., Boiani, M
    • Journal Title

      PLoS One

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21240044
  • [Presentation] C57BL/6JおよびMus spretus由来ミトコンドリアゲノムを有する異質性マウス系統の開発2016

    • Author(s)
      設楽浩志、曹麗琴、山口碧、米川博通、多屋長治
    • Organizer
      第63回日本実験動物学会総会
    • Place of Presentation
      ミューザ川崎シンフォニーホール(神奈川県川崎市)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-25430101
  • [Presentation] 1日の時間変化による組織ミトコンドリアDNA量の解析2013

    • Author(s)
      島貫 碧、米川 博通、設楽 浩志
    • Organizer
      第60日本実験動物学会総会
    • Place of Presentation
      つくば国際会議場(茨城県つくば市)
    • Data Source
      KAKENHI-PROJECT-25430101
  • [Presentation] Proportion of large deleted mitochondrial DNA in single primary adherent cells from mouse tail2013

    • Author(s)
      Midori Shimanuki, Junya Yamaguchi, Choji Taya, Hiromichi Yonekawa, Jun-Ichi Hayashi, Hiroshi Shitara
    • Organizer
      International Symposium on Mitochondria 2013: The 13th Conference of Japanese Society of Mitochondrial Research and Medicine (J-Mit)
    • Place of Presentation
      Roppongi Academyhills 49 (Tokyo, Japan)
    • Data Source
      KAKENHI-PROJECT-25430101
  • [Presentation] マウス初代接着性細胞におけるミトコンドリア核様体の挙動解析2013

    • Author(s)
      山口 潤也、島貫 碧、米川 博通、設楽 浩志
    • Organizer
      第60日本実験動物学会総会
    • Place of Presentation
      つくば国際会議場(茨城県つくば市)
    • Data Source
      KAKENHI-PROJECT-25430101
  • [Presentation] マウスモデルを用いたTfam過剰発現によるミトコンドリア機能低下の抑制効果の解析2011

    • Author(s)
      設楽浩志、西山哲史、中田和人、小野富男、佐藤晃嗣、鈴木英紀、小川哲弘、正木晴彦、林純一、米川博通
    • Organizer
      第58日本実験動物学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21240044
  • [Presentation] ミトコンドリア転写因子A過剰発現によるミトコンドリア機能低下の抑制効果2011

    • Author(s)
      設楽浩志、中田和人、林純一、米川博通
    • Organizer
      第84回日本生化学会大会(シンポジウム)
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21240044
  • [Presentation] Mitochondrial imaging of in tissues by using mtDsRed2-Tg mouse strain2011

    • Author(s)
      Yamaguchi, J., Nishiyama, S., Shimanuki, M., Ono, T., Sato, A., Nakada, K., Hayashi, J-I., Yonekawa, H., Shitara, H
    • Organizer
      The 10th Transgenic Technology Meeting(TT2011)
    • Place of Presentation
      Florida, USA
    • Data Source
      KAKENHI-PROJECT-21240044
  • [Presentation] マウスにおけるmtDNAの遺伝様式2010

    • Author(s)
      設楽浩志、米川博通
    • Organizer
      日本植物学会第74回大会
    • Place of Presentation
      春日井、愛知県(招待講演)
    • Data Source
      KAKENHI-PROJECT-21240044
  • [Presentation] マウスにおけるmtDNAの遺伝様式2010

    • Author(s)
      設楽浩志、米川博通
    • Organizer
      日本植物学会第74回大会
    • Place of Presentation
      春日井、愛知県(招待講演)
    • Data Source
      KAKENHI-PROJECT-21650102
  • [Presentation] マウス初代培養細胞におけるミトコンドリア速度解析2009

    • Author(s)
      設楽浩志、佐藤晃嗣、島貫碧、林純一、米川博通
    • Organizer
      第55日本実験動物学会総会
    • Place of Presentation
      大宮
    • Data Source
      KAKENHI-PROJECT-21240044
  • [Presentation] 2種類のプロモーターで制御可能なTRECK法(DPD-TRECK法)の開発2009

    • Author(s)
      山口潤也, 米川博通
    • Organizer
      第56回日本実験動物学会総会
    • Place of Presentation
      大宮ソニックシティー
    • Data Source
      KAKENHI-PROJECT-19650109
  • [Presentation] Gene therapy of mitochondrial diseases in a mouse model2009

    • Author(s)
      設楽浩志、西山哲史、中田和人、林純一、米川博通
    • Organizer
      第32回日本分子生物学会年会.ワークショップ
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21240044
  • [Presentation] 標的細胞ノックアウト法の胎仔組織への応用2008

    • Author(s)
      松岡邦枝、土屋真衣子、設楽浩志、松尾千古、河野憲二、米川博通
    • Organizer
      BMB2008(第31回日本分子生物学会年会、第81回日本生化学会大会合同大会)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-18200028
  • [Presentation] 標的細胞ノックアウト法の胎仔組織への応用2008

    • Author(s)
      松岡邦枝、土屋真衣子、設楽浩志、松尾千古、河野憲二、米川博通
    • Organizer
      日本実験動物科学技術2008(第55回日本実験動物学会総会・第42回日本実験動物技術者協会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-18200028
  • [Presentation] 標的細胞ノックアウト法の胎仔組織への応用2008

    • Author(s)
      松岡邦枝, 米川博通, 他
    • Organizer
      (BMB2008)第31回日本分子生物学会年会、第81回日本生化学大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-18200028
  • [Presentation] Improvement of a tissue-specific gene expression for TRECK method using a BAC clone.2008

    • Author(s)
      Yonekawa, H., Shibata, K., Sekine, M., Matsuoka, K., Shitara, H., Taya, C. Amano, T.
    • Organizer
      The 22nd International Mammalian Genome Conference (IMGC2008)
    • Place of Presentation
      Prague, Czech
    • Data Source
      KAKENHI-PROJECT-18200028
  • [Presentation] Improvement of a tissue-specific gene expression for TRECK method using a BAC clone2008

    • Author(s)
      H. Yonekawa, K. Shibata, M. Sekine, K. Matsuoka, H. Shitara, C. Taya, T. Amano
    • Organizer
      The 22nd International Mammalian Genome Conference (IMGC2008)
    • Place of Presentation
      Prague, Czech
    • Data Source
      KAKENHI-PROJECT-18200028
  • [Presentation] 標的細胞ノックアウト法の胎仔組織への応用2008

    • Author(s)
      松岡邦枝, 米川博通, 他
    • Organizer
      日本実験動物科学技術2008(第55回日本実験動物学会総会・第42回日本実験動物技術者協会総会)
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-18200028
  • [Presentation] ヒト肝置換Tgマウスの作製方法2008

    • Author(s)
      米川博通、松岡邦枝
    • Organizer
      第7回研究交流フォーラム
    • Place of Presentation
      東京
    • Year and Date
      2008-02-27
    • Data Source
      KAKENHI-PROJECT-18200028
  • 1.  MORIWAKI Kazuo (50000229)
    # of Collaborated Projects: 16 results
    # of Collaborated Products: 0 results
  • 2.  SHITARA Hiroshi (90321885)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 30 results
  • 3.  KOHARA Michinori (10250218)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 3 results
  • 4.  TAYA Choji (90175456)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 8 results
  • 5.  SHIROISHI Toshihiko (90171058)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 6.  KARASUYAMA Hajime (60195013)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 3 results
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  • 147.  KRUYKOV A
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  • 148.  于 国徳
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  • 153.  金井 晃
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  • 156.  YAMAJI Kayoko
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  • 157.  ISHIWATA Kenji
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  • 158.  WATANABE Naohiro
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  • 159.  SUGIMOTO Michihiko
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  • 160.  YASAKA TAKU
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  • 161.  SEKI Yuta
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  • 162.  SUZUKI Sari
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  • 163.  中田 和人
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  • 164.  島貫 碧
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  • 165.  石川 香
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  • 166.  吉川 宗一郎
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    # of Collaborated Products: 1 results
  • 167.  山西 吉典
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  • 168.  橋爪 脩
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    # of Collaborated Products: 1 results
  • 169.  阿部 訓也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 170.  森 晶夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 171.  佐伯 真弓
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 172.  高田 豊行
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    # of Collaborated Products: 1 results
  • 173.  日比野 浩
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 174.  宮坂 勇輝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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