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ISHIURA Shoichi  石浦 章一

ORCIDConnect your ORCID iD *help
Researcher Number 10158743
Other IDs
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Affiliation (based on the past Project Information) *help 2017: 同志社大学, 生命医科学部, 教授
2013 – 2014: 東京大学, 大学院総合文化研究科, 教授
2006: 東京大学, 大学院総合文化研究科, 教授
1997 – 2005: 東京大学, 大学院・総合文化研究科, 教授
2004: The University of Tokyo, Professor, 大学院総合文化研究科, 教授 … More
1998: University of Tokyo, Graduate School of Arts & Sciences Professor, 大学院・総合文化研究所, 教授
1993 – 1997: Institute of Molecular and Cellular Biosciences, The University of Tokyo, Associate Professor, 分子細胞生物学研究所, 助教授
1992 – 1993: Univ. of Tokyo, Inst. Appl. Micro., Assoc. Prof, 応用微生物研究所, 助教授
1991: 国立精神, 神経センター・神経研究所・疾病研究第一部, 室長
1991: Neuroscience Section Chief, 神経センター・神経研究所疾病研究第一部, 室長
1990: 国立精神, 神経センター神経研究所, 室長
1990: Division of Neuromuscular Research National Institute of Neuroscience Division h, 室長
1990: 国立精神神経センター神経研究所, 疾病研究第一部, 室長
1988 – 1990: 国立精神神経センター, 神経研究所, 室長
1989: 国立精神, 神経センター・神経研究所・疾病研究第一部, 室長
1989: NCNP, NIN, Division of Neuromuscular Research, Section Chief, 神経センター神経研究所・疾病研究第一部, 室長
1988: 国立精神, 神経センター神経研究所・疾病研究第1部, 室長
1988: National Institute of Neuroscience, NCNP. Section Chief., 神経研究所, 室長
1987: National Institute of Neuroscience,Section Chief, 神経センター・神経研究所・疾病研究第一部, 室長
1987: 国立精神・神経センター, 神経研究所疾病研究第一部, 室長
1986: 国立精神, 神経センター神経研究所疾病研究第一部, 室長 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Neuroscience in general / Functional biochemistry / 神経内科学 / Functional biochemistry / General medical chemistry
Except Principal Investigator
Neurology / Structural biochemistry / General medical chemistry / Functional biochemistry … More / Neurochemistry/Neuropharmacology / Functional biochemistry / Philosophy/Ethics / Developmental mechanisms and the body works / 実験系心理学 / Pediatrics Less
Keywords
Principal Investigator
アルツハイマー病 / ADAM / プロテアーゼ / アミロイド / セクレターゼ / Alzheimer's disease / トリプレット・リピート / アポトーシス / MDC9 / アミロイド前駆体 … More / 治療 / 情報伝達 / 分泌 / Amyloid / Secretion / Protease / BACE1 / 老化 / 脳神経疾患 / 遺伝子 / 蛋白質 / 神経科学 / 筋緊張性ジストロフィー / イオンチャンネル / 筋小胞体 / 培養細胞 / タンパク分解 / ポリアミノ酸 / 細胞死 / モデル / 細胞 / ホモポリアミノ酸 / トリプレットリピート / オートファジー / ポリグルタミン / ポリアラニン / 筋ジストロフィー / ジストロフィン / Dystrophy / Dystrophin / treatment / C-キナーゼ / アミロイドβ蛋白質 / Signal transduction / C kinase / プロセシング / ソーティング / Signal molecules / Processing / αセレクターゼ / βセレクターゼ / BACE1阻害剤 / 阻害剤 / Tg2576 / βタンパク質 / KMI429 / BACE / ニカストリン / a-Secretase / β-secretase / BACE1 inhibitor / セレクターゼ / シェッディング / αセクレターゼ / dsRNA / 脳 / amyloid / protease / secretase / shedding / therapy / aging / Tリンパ球 / 細胞障害 / ミオパチー / パーフォリン / キラーTリンパ球 / CTL / T-lymphocyte / Cytotoxicity / Myopathy / Perforin / Killer lymphocyte … More
Except Principal Investigator
カルパイン / アルツハイマー病 / 筋ジストロフィー / プロテアーゼ / ジストロフィン / プロテインキナーゼC / ジストロフィン類似蛋白質 / カテプシン / 転写因子 / カルパスタチン / 遺伝子診断 / DNA diagnosis / muscular dystrophy / カルシウム / calpain / calcium / 蛋白質分解 / 筋ジストロフィー症 / p94 / アミロイドタンパク質 / アミロイド前駆体 / 遺伝子発現 / バイオモジュレーター / プロテアソーム / ユビキチン / 脳細胞 / アミロイド蛋白質 / 糖原病II型 / acid α-glucosidase(GAA) / cDNA / 筋芽細胞 / 遺伝子治療 / 細胞移入 / 痴呆 / タウオパチー / アミロイド蛋白 / タウ / ブレインバンク / 神経発生 / RIP / sシグナル伝達 / 細胞応答 / γセクレターゼ / タンパク質分秋 / 哲学 / 人格 / 自然災害 / 物質 / 生命 / 災害 / リスク / 曖昧性 / 放射能 / 物体 / 言語 / 自由 / 責任 / 作業記憶 / 歩行 / 障害物回避動作 / マウス / 身体性 / 3xTg マウス / 障害物回避歩行 / 障害物回避 / プロテアソ-ム / 多機能プロテア-ゼ / 多成分複合体 / 構造解析 / 高分子量プロテア-ゼ / 分子遺伝学 / 多機能プロテア-ゼ複合体 / 細胞内プロテア-ゼ / 20S環状粒子 / cDNAクロ-ニング / 発生と分化 / Proteasomes / Multicatalytic protease / Structural analysis / Multisubunit complex / High molecular weight protease / デュシャンヌ型筋ジストロフィ- / ベッカ-型筋ジストロフィ- / ジストロフィンテスト / 免疫細胞化学 / イムノブロット / 遺伝子産物 / multiplexーPCR法 / 免疫組織化学 / DMD遺伝子 / Duchenne muscular dystrophy / Becker muscular dystrophy / Dystrophin / Dystrophin test / Immunocytochemistry / Immunoblotting / Embryonic Stem Cell / キメラマウス / mdxマウス / 細胞標識 / 筋ジストロフィ- / 発生工学 / トランスジェニックマウス / Embryonic stem cell / トランスジエニツクマウス / 胚幹細胞 / Embryonic stem Cell / chimera mouse / mdx mouse / Cellular marker / developmental biotechnology / transgeneic mouse / 情報伝達 / プロテインキナ-ゼC / ダウンレギュレ-ション / ホルボ-ルエステル / Protein Kinase C / signal transduction / 老年痴呆 / 分子機構 / 神経栄養因子 / 神経細胞死 / 遺伝子解析 / 細胞死 / ベータたんぱく / タウたんぱく / アポEたんぱく / 家族性アルツハイマー病 / 神経原線維変化 / PHF / タウ蛋白 / 老人斑 / Abeta蛋白 / β蛋白 / βアミロイド前駆蛋白 / senile dementia / molecular mechanisms / Alzheimer's disease / neurotrophic factors / neuronal cell death / gene analysis / カルシユム / caplapin / proteases / proteolysis / タンパク分解 / 寿命 / PEOTEIN DEGRADATION / CALCIUM / HALF-LIFE / MUSCULAR DYSTROPHY / コネクチン / タイチン / フォドリン / カルバイン / 筋肉 / connectin / titin / protease / fodrin / ドーパミン / ベイズアプローチ / ギブスサンプリング / 遺伝規定性 / 線虫 / モノアミン / ドーパミン情報伝達系 / ベイズ的アプローチ / DAD多型 / TCI / 構造方程式モデル / MCMC / ギャンブル課題 / 抑うつ傾向 / アパシー傾向 / dopamine / Bayesian Approach / Gibbs Sampling / genetic determinacy / Nematoda / monoamine / Rimmed vacuoleクロロキン / カテプレンBjL / EST / クロロキン / Rimmed racuole / リソゾーム / カテプシンB&L / Chloroquine myopathy / lysosome / cathepsins B and L / 多発性筋炎 / 細胞障害性T-リンパ球 / パ-フォリン / セリンエステラ-ゼ / パ-フォリンインヒビタ- / パーフォリン / セリンエステラーゼ / ポリアラニン / トリプレットリピート / トリプレットリピート病 / ポリアミノ酸 / ポリグルタミン Less
  • Research Projects

    (35 results)
  • Research Products

    (75 results)
  • Co-Researchers

    (85 People)
  •  Fundamental research for understanding the working memory during locomotion

    • Principal Investigator
      YANAGIHARA Dai
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Developmental mechanisms and the body works
    • Research Institution
      The University of Tokyo
  •  Molecular mechanism of polyalanine expansion disorders

    • Principal Investigator
      OMA Yoko
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Saitama Medical University
  •  Theoretical and Practical Studies on the Crossing between Philosophy and Natural Science concerning Matter, Life, and Person

    • Principal Investigator
      ICHINOSE Masaki
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Philosophy/Ethics
    • Research Institution
      The University of Tokyo
  •  RIPによる細胞内情報伝達機構

    • Principal Investigator
      鈴木 利治
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Hokkaido University
  •  アミノ酸ホモポリマー沈着による病態の階層モデルPrincipal Investigator

    • Principal Investigator
      石浦 章一
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional biochemistry
    • Research Institution
      The University of Tokyo
  •  Development and use of amyloid secretase modulators in Alzhaimer's disease.Principal Investigator

    • Principal Investigator
      ISHIURA Shoichi
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  ドーパミン関連遺伝子の効果のグラフィックベイズ分析

    • Principal Investigator
      SHIGEMASU Kazuo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      実験系心理学
    • Research Institution
      The University of Tokyo
  •  Shedding activity and physiological role of a newly-found ADAM family metalloprotease familyPrincipal Investigator

    • Principal Investigator
      ISHIURA Shoichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      The University of Tokyo
  •  膜タンパク質セクレターゼ群の情報クロストークPrincipal Investigator

    • Principal Investigator
      石浦 章一
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  メタロプロテアーゼによる細胞膜結合型蛋白質の分泌機構の解明Principal Investigator

    • Principal Investigator
      石浦 章一
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  アルツハイマー病発症分子機構に関する総合的研究

    • Principal Investigator
      森 啓
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka City University
  •  アルツハイマー病発症に関わる新規プロテアーゼの検索Principal Investigator

    • Principal Investigator
      石浦 章一
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  Analysis of molecular mechanism of muscular dystrophy involving skeletal muscle-specific calpain and connectin

    • Principal Investigator
      SUZUKI Koichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Functional biochemistry
    • Research Institution
      Institute of Molecular and Cellular Biosciences, University of Tokyo
  •  トリプレット・リピート伸長cDNA発現細胞とアポトーシスPrincipal Investigator

    • Principal Investigator
      石浦 章一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Isolation of signal molecules on the secretion of amyloid precursorPrincipal Investigator

    • Principal Investigator
      ISHIURA Shoichi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neuroscience in general
    • Research Institution
      The University of Tokyo
  •  脳細胞選択死のモデルとしての異常cDNA発現細胞の解析

    • Principal Investigator
      鈴木 絋一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  α-グルコシダーゼcDNA導入細胞を用いた糖原病II型の遺伝子治療

    • Principal Investigator
      臼杵 扶佐子
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Teikyo University
  •  Determination and regulation of half-life of the proteins

    • Principal Investigator
      SUZUKI Koichi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      University of Tokyo
  •  転写因子の代謝と転写調節

    • Principal Investigator
      鈴木 鉱一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  バイオモジュレーターとしてのプロテアーゼ

    • Principal Investigator
      鈴木 紘一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo
  •  Secretion of amyloid precursor protein via signal transduction pathwayPrincipal Investigator

    • Principal Investigator
      ISHIURA Shoichi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Neuroscience in general
    • Research Institution
      The University of Tokyo
  •  転写因子の代謝と転写調節

    • Principal Investigator
      鈴木 紘一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  ジストロフィンの欠損を補う胎児型アイソフォームの発現調節

    • Principal Investigator
      鈴木 紘一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Structure and physiological function of novel calpain species

    • Principal Investigator
      SUZUKI Koichi
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      University of Tokyo
  •  ジストロフィン類似蛋白質の発現と病態

    • Principal Investigator
      SUZUKI Koichi
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  アミロイド前駆体セクレターゼの同定,発現と制御

    • Principal Investigator
      鈴木 紘一
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  MOolecular mechanism of senile dementia. -summary of research-

    • Principal Investigator
      TATEISHI Jun
    • Project Period (FY)
      1992 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      KYUSHU UNIVERSITY
  •  Role of dystrophin-related protein in the pathogenesis of Duchenne muscular dystrophy.Principal Investigator

    • Principal Investigator
      ISHIURA Shoichi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      神経内科学
    • Research Institution
      Institute of Molecular and Cellular Biosciences, The University of Tokyo
  •  Mechanism of down-regulation of protein kinase C and its implications in signal transduction

    • Principal Investigator
      SUZUKI Koichi
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokyo
  •  Manipulation of mdx mouse embryos

    • Principal Investigator
      HANAOKA Kazunori
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      National Institute of Neuroscience NCNP
  •  Structure and Cell Biology of a Novel Multicatalytic Proteinase Complex

    • Principal Investigator
      ICHIHARA Akira
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokushima
  •  Molecular Pathological Analysis of the Duchenne Muscular Dystrophy Gene Product, Dystrophin.

    • Principal Investigator
      ARAHATA Kiichi
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP)
  •  Exploration of the mechanism of muscle necrosis in Polymyositis.

    • Principal Investigator
      SUGITA Hideo
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      National Center of Neurology and Psychiatry (NCNP)
  •  Studies on the mechanism of Cytotoxic T-lymphocyte (CTL)-mediated muscle breakdownPrincipal Investigator

    • Principal Investigator
      ISHIURA Shoichi
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      National Institute of Neuroscience, NCNP
  •  Chloroquine myopathy,its mechanism and treatment with cysteine proteinase inhibitor,EST

    • Principal Investigator
      SUGITA Hideo
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      National Institute of Neuroscience,NCNP

All 2015 2014 2013 2007 2006 2005 2004 2003 2002 2001 2000 Other

All Journal Article Presentation Book

  • [Book] ADAM9. In Proteases in Biology and Disease, volume 4, The ADAM Family of Proteases. (eds. Hooper, Lendeckel)(Kluwer Plenum)2005

    • Author(s)
      Ishiura, S.
    • Total Pages
      344
    • Publisher
      New York(in press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Book] 遺伝子が明かす脳と心のからくり2004

    • Author(s)
      石浦章一
    • Total Pages
      270
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Book] APP α-secretase, a novel target for Alzheimer drug therapy. In Ab metabolism and Alzheimer's Disease (T.C.Saido. ed.)2003

    • Author(s)
      Ishiura, S., Asai, M., Hattori, C., Hotoda, N., Szabo.B., Sasagawa, N., Tanuma, S.
    • Total Pages
      165
    • Publisher
      Eurekah Press
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Book] PP α-secretase, a novel target for Alzheimer drug therapy. in Aβ metabolism and Alzheimer's Disease (T.C. Saido, ed.)2003

    • Author(s)
      Ishiura, S., Asai, M., Hattori, C., Hotoda, N., Szabo.B., Sasagawa, N., Tanuma, S.
    • Publisher
      Eurekah Press
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Book] IQ遺伝子2002

    • Author(s)
      石浦章一
    • Total Pages
      182
    • Publisher
      丸善
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13480202
  • [Book] IQ genes.2002

    • Author(s)
      Ishiura, S.
    • Total Pages
      182
    • Publisher
      Maruzen
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13480202
  • [Book] ADAM9. In Proteases in Biology and Disease, volume 4, The ADAM Family of Proteases. (eds. Hooper, Lendeckel) Kluwer Plenum,

    • Author(s)
      Ishiura, S.
    • Publisher
      New York (in press)
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Nuclear localization of MBNL1: splicing-mediated autoregulation and repression of repeat-derived aberrant proteins.2015

    • Author(s)
      Kino Y, Washizu C, Kurosawa M, Oma Y, Hattori N, Ishiura S, Nukina N.
    • Journal Title

      Human Molecular Genetecs

      Volume: 24 Pages: 740-56

    • DOI

      10.1093/hmg/ddu492

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22110004, KAKENHI-PROJECT-25461299, KAKENHI-PROJECT-25860844
  • [Journal Article] Manumycin A corrects aberrant splicing of Clcn1 in myotonic dystrophy type 1 (DM1) mice.2013

    • Author(s)
      Kosuke Oana, Yoko Oma, Satoshi Suo, Masanori P. Takahashi, Ichizo Nishino, Shin'ichi Takeda, Shoichi Ishiura
    • Journal Title

      Sci Rep

      Volume: VOL.3 Pages: 2142-2142

    • DOI

      10.1038/srep02142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J08474, KAKENHI-PROJECT-23591245, KAKENHI-PROJECT-25860844
  • [Journal Article] Expression of MBNL and CELF mRNA transcripts in muscles with myotonic dystrophy.2007

    • Author(s)
      Nezu, Y., Kino, Y., Sasagawa, N., Nishino, I., Ishiura, S.
    • Journal Title

      Neuromuscular Disorders 17

      Pages: 306-312

    • Data Source
      KAKENHI-PROJECT-17657043
  • [Journal Article] A novel β-secretase inhibitor KMI-429 reduces amyloid β peptide (Aβ) production in amyloid precursor protein (APP) transgenic and wild-type mice.2006

    • Author(s)
      Asai, M., Hattori, C., Iwata, N., Saido, S.C., Sasagawa, N., Szabo, B., Hashimoto, Y., Maruyama, K., Tanuma, S., Kiso, Y., Ishiura, S.
    • Journal Title

      J.Neurochem. 96

      Pages: 533-540

    • Data Source
      KAKENHI-PROJECT-17657043
  • [Journal Article] The Hesr1 knockout mice exhibit behavioral alterations through the dopaminergic nervous system.2006

    • Author(s)
      Fuke, S., Minami, N., Kokubo, H., Yoshikawa, A., Yasumatsu, H., Sasagawa, N., Saga, Y., Tsukahara, T., Ishiura, S.
    • Journal Title

      J.Neurosci.Res. 84

      Pages: 1555-1563

    • Data Source
      KAKENHI-PROJECT-17657043
  • [Journal Article] A simple, one step cloning method to obtain long artificial triplet repeats.2006

    • Author(s)
      Sasagawa, N., Ishiura, S.
    • Journal Title

      Anal.Biochem. 357

      Pages: 308-310

    • Data Source
      KAKENHI-PROJECT-17657043
  • [Journal Article] BACE1 interacts with lipid raft proteins2006

    • Author(s)
      Hattori, C., Asai, M., Onishi, H., Sasagawa, N., Hashimoto, Y., Saido, T.C., Maruyama, K., Mizutani, S., Ishiura.S.
    • Journal Title

      J.Neurosci.Res. 84

      Pages: 912-917

    • Data Source
      KAKENHI-PROJECT-17657043
  • [Journal Article] DAPT-induced intracellularaccumulations of longer amyloid □-protein : Further implications for the mechanism of intramembrane cleavage by □-secretase.2006

    • Author(s)
      Yagishita, S., Kawashima-Morishima, M., Tanimura, Y., Ishiura, S., Ihara, Y.
    • Journal Title

      Biochemistry 45

      Pages: 3952-3960

    • Data Source
      KAKENHI-PROJECT-17657043
  • [Journal Article] Regulation of splicing by MBNL and CELF family of RNA binding protein.2005

    • Author(s)
      Ishiura, S., Kino, Y., Nezu, Y., Onishi, H., Ohno, E., Sasagawa, N.
    • Journal Title

      Acta Myologica 14

      Pages: 74-77

    • Data Source
      KAKENHI-PROJECT-17657043
  • [Journal Article] Characterization of a novel D2-like dopamine receptor with a truncated splice variant and a D1-like dopamine receptor unique to invertebrates from Caenorhabditis elegans.2005

    • Author(s)
      Sugiura, M., Fuke, S., Suo, S., Sasagawa, N., Van Tol, H.H.M.Ishiura, S.
    • Journal Title

      J.Neurochem. 94

      Pages: 1146-1157

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Denervation enhances the expression of SHPS-1 in the rat skeletal muscle.2005

    • Author(s)
      Mitsuhashi, H., Ysohikawa, A., Sasagawa, N., Hayashi, Y., Ishiura, S.
    • Journal Title

      J.Biochem. 137

      Pages: 495-502

    • Data Source
      KAKENHI-PROJECT-17657043
  • [Journal Article] Comparative analysis of the cytotoxicity of homopolymeric amino acid2005

    • Author(s)
      Oma, Y., Kino, Y., Sasagawa, N., Ishiura S.
    • Journal Title

      Biochim.Biophys.Acta 1748

      Pages: 174-179

    • Data Source
      KAKENHI-PROJECT-17657043
  • [Journal Article] Characterization of a novel D2-like dopamine receptor with a truncated splice variant and a D1-like dopamine receptor unique to invertebrates from Caenorhabditis elegans.2005

    • Author(s)
      Sugiura, M., Fuke, S., Suo, S., Sasagawa, N., Van Tol, H.H.M., Ishiura, S.
    • Journal Title

      J.Neurochem. 94(in press)

      Pages: 1146-1157

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Denervation enhances the expression of SHPS-1 in the rat skeletal muscle.2005

    • Author(s)
      Mitsuhashi, H., Yoshikawa, A., Sasagawa, N., Hayashi, Y.Ishiura, S.
    • Journal Title

      J.Biochem. 137

      Pages: 495-502

    • NAID

      10017344589

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Identification and characterization of Hesr1/Hey1 as a candidate trans-acting factor on gene expression through the 3' non-coding polymorphic region of the human dopamine transporter (DAT1) gene.2005

    • Author(s)
      Fuke, S., Sasagawa, N., Ishiura, S.
    • Journal Title

      J.Biochem. 137

      Pages: 205-216

    • NAID

      10017343257

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Characterization of a novel D2-like dopamine receptor with a truncated splice variant and a D1-like dopamine receptor unique to invertebrates from Caenorhabditis elegans.2005

    • Author(s)
      Sugiura, M., Fuke, S., Suo, S., Sasagawa, N., Van Tol, H.H.M., Ishiura, S.
    • Journal Title

      J.Neurochem. 94

      Pages: 1146-1157

    • Data Source
      KAKENHI-PROJECT-17657043
  • [Journal Article] Independent accumulations of tau and amyloid b protein in the human entorhinal cortex.2005

    • Author(s)
      Katsuno, T., Morishima-Kawashima, M., Saito, Y., Yamanouchi, H., Ishiura, S., Muyarama, S., Ihara, Y.
    • Journal Title

      Neurology 64

      Pages: 687-692

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Comparative analysis of the cytotoxicity of homopolymeric amino acids.2005

    • Author(s)
      Oma, Y., Kino, Y., Sasagawa, N.Ishiura, S.
    • Journal Title

      Biochim.Biophys.Acta 1748

      Pages: 174-179

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Denervation enhances the expression of SHPS-1 in the rat skeletal muscle.2005

    • Author(s)
      Mitsuhashi, H., Yoshikawa, A., Sasagawa, N., Hayashi, Y., Ishiura, S.
    • Journal Title

      J.Biochem. 137

      Pages: 495-502

    • NAID

      10017344589

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Independent accumulations of tau and amyloid β protein in the human entorhinal cortex.2005

    • Author(s)
      Katsuno, T., Morishima-Kawashima, M., Saito, Y., Yamanouchi, H., Ishiura, S., Muyarama, S., Ihara, Y.
    • Journal Title

      Neurology 64

      Pages: 687-692

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Comparative analysis of the cytotoxicity of homopolymeric amino acids.2005

    • Author(s)
      Oma, Y., Kino, Y., Sasagawa, N., Ishiura, S.
    • Journal Title

      Biochim.Biophys.Acta 1748

      Pages: 174-179

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Identification and characterization of Hesrl/Hey1 as a candidate trans-acting factor on gene expression through the 3' non-coding polymorphic region of the human dopamine transporter (DAT1) gene.2005

    • Author(s)
      Fuke, S., Sasagawa, N.Ishiura, S.
    • Journal Title

      J.Biochem. 137

      Pages: 205-216

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Intracellular localization of homopolymeric amino acid-containing proteins expressed in mammalian cells.2004

    • Author(s)
      Oma, Y., Kino, Y., Sasagawa, N., Ishiura S.
    • Journal Title

      J.Biol.Chem. 278

      Pages: 21217-21222

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Expression of amyloid-β1-40 and 1-42 peptides in Capsicum annum var. angulosum for oral immunization.2004

    • Author(s)
      Szabo, B., Hori, K., Nakajima, A., Sasagawa, N., Watanabe, Y.Ishiura, S.
    • Journal Title

      ASSAY and Drug Development Technologies. 2

      Pages: 383-388

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] KMI-358 and KMI-370, highly potent and small-sized BACE 1 inhibitors containing phenylnorstatine.2004

    • Author(s)
      Kimura, T., Shuto, D., Kasai, S., Liu, P., Hidaka, K., Hamada, T., Hayashi, Y., Hattori, C., Asai, M., Kitazume, S., Saido, T.C., Ishiura, S.Kiso, Y.
    • Journal Title

      Bioorg.Med.Chem.Lett. 14

      Pages: 1527-1531

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Intracellular localization of homopolymeric amino acid-containing proteins expressed in mammalian cells.2004

    • Author(s)
      Oma, Y., Kino, Y., Sasagawa, N.Ishiura S.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 21217-21222

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Expression of amyloid-bl-40 and 1-42 peptides in Capsicum annum var. angulosum for oral immunization.2004

    • Author(s)
      Szabo, B., Hori, K., Nakajima, A., Sasagawa, N., Watanabe, Y., Ishiura, S.
    • Journal Title

      ASSAY and Drug Development Technologies 2

      Pages: 383-388

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Mammalian D-aspartyl endopeptidase : a scavenger for noxious racemized proteins in aging.2004

    • Author(s)
      Kinouchi, T., Ishiura, S., Mabuchi, Y., Urakami-Manaka, Y., Nishio, H., Nishiuchi, Y., Tsunemi, M., Takeda K., Watanabe, M., Ikeda, M., Matsui, H., Tomioka, S., Kawahara, H., Hamamoto, T., Suzuki.K., Kagawa, Y.
    • Journal Title

      Biochem.Biophys.Res.Commun 314

      Pages: 730-736

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Muscleblind protein, MBNL1/EXP, binds specifically to CHHG repeats.2004

    • Author(s)
      Kino, Y., Oma, Y., Sasagawa, N., Ishiura, S.
    • Journal Title

      Human Mol.Genet. 13

      Pages: 495-507

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] KMI-358 and KMI-370, highly potent and small-sized BACE1 inhibitors containing phenylnorstatine.2004

    • Author(s)
      Kimura.T., Shuto, D., Kasai, S., Liu, P., Hidaka, K., Hamada, T., Hayashi, Y., Hattori, C., Asai, M., Kitazume, S., Saido, T.C., Ishiura, S., Kiso, Y.
    • Journal Title

      Bioorg. Med. Chem. Lett. 14

      Pages: 1527-1531

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] ADAMs, a disintegrin metalloproteinases, mediate shedding of oxytocinase.2004

    • Author(s)
      Ito, N., Nomura, S., Iwase, A., Ito, T., Kikkawa, F., Tsujimoto, M., Ishiura, S., Mizutani, S.
    • Journal Title

      J.Biochem. 314

      Pages: 1008-1013

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Dopamine receptors in C.elegans.2004

    • Author(s)
      Suo, S., Ishiura, S., Van Tol, H.H.M.
    • Journal Title

      Eur.J.Pharmacol. 500

      Pages: 159-166

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] BDopamine receptors in C.elegans.2004

    • Author(s)
      Suo, S., Ishiura, S., Van Tol, H.H.M.
    • Journal Title

      Eur.J.Pharmacol. 500

      Pages: 159-166

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Mammalian D-aspartyl endopeptidase : a scavenger for noxious racemized proteins in aging.2004

    • Author(s)
      Kinouchi, T., Ishiura, S., Mabuchi, Y., Urakami-Manaka, Y., Nishio, H., Nishiuchi, Y., Tsunemi, M., Takeda, K., Watanabe, M., Ikeda, M., Matsui, H., Tomioka, S., Kawahara, H., Hamamoto, T., Suzuki, K, Kagawa, Y.
    • Journal Title

      Biochem.Biophys.Res.Commun. 314

      Pages: 730-736

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] ADAMs, a disintegrin metalloproteinases, mediate shedding of oxytocinase.2004

    • Author(s)
      Ito, N., Nomura, S., Iwase, A., Ito, T., Kikkawa, F., Tsujimoto, M., Ishiura, S.Mizutani, S.
    • Journal Title

      Biochem.Biophys.Res.Commun. 314

      Pages: 1008-1013

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Muscleblind protein, MBNL1/EXP, binds specifically to CHHG repeats.2004

    • Author(s)
      Kino, Y., Oma, Y., Sasagawa, N.Ishiura, S.
    • Journal Title

      Human Mol.Genet. 13

      Pages: 495-507

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] KMI-008, a novel beta-secretase inhibitor containing a hydroxymethylcarbonyl isostere as a transition-state mimic : Design and synthesis of substrate-based octapeptides.2003

    • Author(s)
      Shuto, D., Kasai, S., Kimura T., Liu, P., Hidaka, K., Hamada T., Shibakawa, S., Hayashi, Y., Hattori.C., Szabo, B., Ishiura S., Kiso, Y.
    • Journal Title

      Bioorg. Med. Chem. Lett. 13

      Pages: 4273-4276

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Expression of ARPP-16/19 in rat denervated skeletal muscle.2003

    • Author(s)
      Yoshikawa, A., Mitsuhashi, H., Sasagawa, N., Tsukahara, T., Hayashi, Y., Nishino, I., Goto, Y., Ishiura, S.
    • Journal Title

      J.Biochem. 134

      Pages: 57-61

    • NAID

      10012056067

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] KMI-008, a novel beta-secretase inhibitor containing a hydroxymethylcarbonyl isostere as a transition-state mimic : Design and synthesis of substrate-based octapeptides.2003

    • Author(s)
      Shuto, D., Kasai, S., Kimura, T., Liu, P., Hidaka, K., Hamada, T., Shibakawa, S., Hayashi, Y., Hattori, C., Szabo, B., Ishiura S., Kiso, Y.
    • Journal Title

      Bioorg.Med.Chem.Lett. 13

      Pages: 4273-4276

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Putative function of ADAM9, ADAM10, and ADAM17 as APP α-secretase.2003

    • Author(s)
      Asai, M., Hattori, C., Szabo, B., Sasagawa, N., Maruyama, K., Tanuma, S., Ishiura, S.
    • Journal Title

      Biochem.Biophys.Res.Commun. 301

      Pages: 231-235

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13480202
  • [Journal Article] Cloning and characterization of a C. elegans D2-like dopamine receptor.2003

    • Author(s)
      Suo, S., Sasagawa, N., Ishiura, S.
    • Journal Title

      J.Neurochem. 86

      Pages: 869-878

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Potential link between amyloid beta protein 42 and C-terminal fragment gamma49-99 of beta amyloid precursor protein.2003

    • Author(s)
      Sato, T., Dohmae, N., Qi, Y., Misonou H., Mitsumori, R., Maruyama H., Koo, E.H., Haass, C., Takio, K., Morishima-Kawashima M., Ishiura S., Ihara Y.
    • Journal Title

      J.Biol.Chem. 278

      Pages: 24294-24301

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Putative function of ADAM9, ADAM10, and ADAM17 as APP a-secretase.2003

    • Author(s)
      Asai, M., Hattori, C., Szabo, B., Sasagawa, N., Maruyama, K., Tanuma, S., Ishiura, S.
    • Journal Title

      Biochem.Biophys.Res.Commun. 301

      Pages: 231-235

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Putative function of ADAM9, ADAM 10, and ADAM 17 as APP a-secretase.2003

    • Author(s)
      Asai, M., Hattori, C., Szabo, B., Sasagawa, N., Maruyama, K., Tanuma, S., Ishiura, S.
    • Journal Title

      Biochem.Biophys.Res.Commun. 301

      Pages: 231-235

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Potential link between amyloid beta protein 42 and C-terminal fragment gamma49-99 of beta amyloid precursor protein.2003

    • Author(s)
      Sato, T., Dohmae, N., Qi, Y., Misonou, H., Mitsumori, R., Maruyama, H., Koo, E.H., Haass, C., Takio, K., Morishima-Kawashima, M, Ishiura, S., Ihara, Y.
    • Journal Title

      J.Biol.Chem. 278

      Pages: 24294-24301

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] A secreted form of ADAM9 has an α-secretase activity for APP.2002

    • Author(s)
      Hotoda, N., Koike, H., Sasagawa, N., Ishiura, S.
    • Journal Title

      Biochem.Biophys.Res.Commun. 293

      Pages: 800-805

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13480202
  • [Journal Article] The first molecular evidence that autophagy relates rimmed vacuole formation in chloroquine myopathy.2002

    • Author(s)
      Suzuki, T., Nakagawa, M., Yoshikawa, A., Sasagawa, N., Yoshimori, T., Ohsumi, Y., Nishsino, I., Ishiura, S., Nonaka, I.
    • Journal Title

      J.Biochem. 131

      Pages: 647-651

    • NAID

      10010647759

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] A secreted form of ADAM9 has an a-secretase activity for APP.2002

    • Author(s)
      Hotoda, N., Koike, H., Sasagawa, N., Ishiura, S.
    • Journal Title

      Biochem.Biophys.Res.Commun. 293

      Pages: 800-805

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] The first molecular evidence that autophagy relates rimmed vacuole formation in chloroquine myopathy.2002

    • Author(s)
      Suzuki, T., Nakagawa, M., Yoshikawa, A., Sasagawa, N., Yoshimori, T., Ohsumi, Y., Nishsino, I., Ishiura, S.Nonaka, I.
    • Journal Title

      J.Biochem. 131

      Pages: 647-651

    • NAID

      10010647759

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Identification of a dopamine receptor from Caenohabditis elegans.2002

    • Author(s)
      Suo, S., Sasagawa, N., Ishiura, S.
    • Journal Title

      Neurosci.Lett. 319

      Pages: 13-16

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] BACE1 interacts with nicastrin.2002

    • Author(s)
      Hattori, C., Asai, M., Oma, Y., Kino, Y., Sasagawa, N., Saido, T.C., Mariyama, K., Ishiura, S.
    • Journal Title

      Biochem.Biophys.Res.Commun. 293

      Pages: 1228-1232

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13480202
  • [Journal Article] Identification of a dopamine receptor from Caenohabditis elegans.2002

    • Author(s)
      Suo, S., Sasagawa, N.Ishiura, S.
    • Journal Title

      Neurosci.Lett. 319

      Pages: 13-16

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] BACE 1 interacts with nicastrin.2002

    • Author(s)
      Hattori, C., Asai, M., Oma, Y., Kino, Y., Sasagawa, N., Saido, T.C., Mariyama, K., Ishiura, S.
    • Journal Title

      Biochem.Biophys.Res.Commun. 293

      Pages: 1228-1232

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] A secreted form of ADAM9 has an a-secretase activity for APP.2002

    • Author(s)
      Hotoda, N., Koike, H., Sasagawa, N., Ishiura, S.
    • Journal Title

      Biochem.Biophys.Res. Commun. 293

      Pages: 800-805

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] BACE1 interacts with nicastrin.2002

    • Author(s)
      Hattori, C., Asai, M., Oma, Y., Kino, Y., Sasagawa, N., Saido, T.C., Mariyama, K., Ishiura, S.
    • Journal Title

      Biochem.Biophys.Res.Commun. 293

      Pages: 1228-1232

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] The VNTR polymorphism of the human dopamine transporter (DAT1) gene affects gene expression.2001

    • Author(s)
      Fuke, S., Suo, S., Takahashi, N., Koike, H., Sasagawa, N., Ishiura, S.
    • Journal Title

      The Pharmacogenomics J. 1

      Pages: 152-156

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Alzheimer amyloid α-secretase : a special target for drug development.2001

    • Author(s)
      Ishiura, S., Hotoda, N., Szabo, B., Asai, M., Hattori, C., Tanaka, E., Koike, H., Sasagawa, N.
    • Journal Title

      Psychogeriatrics 1

      Pages: 273-276

    • NAID

      10019049816

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Limited proteolysis of filamin is catalyzed by caspase-3 in U937 and Jurkat cells.2001

    • Author(s)
      Umeda T, Kouchi Z, Kawahara H, Tomioka S, Sasagawa N, Maeda T, Sorimachi H, Ishiura S, Suzuki K.
    • Journal Title

      J.Biochem. 130

      Pages: 535-542

    • NAID

      130003534268

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Alzheimer amyloid α.secretase : a special target for drug development.2001

    • Author(s)
      Ishiura, S., Hotoda, N., Szabo, B., Asai, M., Hattori, C., Tanaka, E., Koike, H.Sasagawa, N.
    • Journal Title

      Psychogeriatrics 1

      Pages: 273-276

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Limited proteolysis of filamin is catalyzed by caspase-3 in U937 and Jurkat cells.2001

    • Author(s)
      Umeda T, Kouchi Z, Kawahara H, Tomioka S, Sasagawa N, Maeda T, Sorimachi H, Ishiura S, Suzuki K
    • Journal Title

      J.Biochem. 130

      Pages: 535-542

    • NAID

      130003534268

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Myopathy phenotype of transgenic mice expressing active site-mutated inactive p94 skeletal muscle-specific calpain, the gene product responsible for limb girdle muscular dystrophy type 2A.2000

    • Author(s)
      Tagawa, K., Taya, C., Hayashi, Y., Nakagawa, M., Ono, Y., Fukuda, R., Karasuyama, H., Toyama-Sorimachi, N., Katsui, Y., Hata, S., Ishiura, S., Nonaka, I., Seyama, Y., Arahata, K., Yonekawa, H., Sorimachi, H., Suzuki, K.
    • Journal Title

      Human Mol.Genet. 9

      Pages: 1393-1402

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Molecular interactions between presenilin and calpain : inhibition of m-calpain protease activity by presenilin-1, 2 and cleavage of presenilin-1 by m-, μ-calpain.2000

    • Author(s)
      Maruyama, K., Usami, M., Kametani, F., Tomita, T., Iwatsubo, T., Saido, T.C., Mori, H., Ishiura, S.
    • Journal Title

      Int.J.Mol.Med. 5

      Pages: 269-273

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Metabolism of amyloid precursor protein in COS cells transfected with a β-secretase candidate.2000

    • Author(s)
      Koike, H., Kouchi, Z., Kinouchi, T., Maeda, T., Sorimachi, H., Saido.T.C., Maruyama, K., Okuyama, A., Suzuki, K., Ishiura, S.
    • Journal Title

      Cytotechnology 33

      Pages: 213-219

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Myopathy phenotype of transgenic mice expressing active site-mutated inactive p94 skeletal muscle-specific calpain, the gene product responsible for limb girdle muscular dystrophy type 2A.2000

    • Author(s)
      Tagawa, K., Tgya, C., Hayashi, Y., Nakagawa, M., Ono, Y., Fukuda, R., Karasuyama, H., Toyama-Sorimachi, N., Katsui, Y., Hata S., Ishiura S., Nonaka, I., Seyama Y., Arahata, K., Yonekawa.H., Sorimachi, H., Suzuki, K.
    • Journal Title

      Human Mol.Genet 9

      Pages: 1393-1402

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Molecular interactions between presenilin and calpain : inhibition of m-calpain protease activity by presenilin-1, 2 and cleavage of presenilin-1 by m-, μ-calpain.2000

    • Author(s)
      Maruyama, K., Usami, M., Kametani, F., Tomita, T., Iwatsubo, T., Saido, T.C., Mori, H, Ishiura, S.
    • Journal Title

      Int.J.Mol.Med. 5

      Pages: 269-273

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Journal Article] Metabolism of amvloid precursor protein in COS cells transfected with a β-secretase candidate.2000

    • Author(s)
      Koike, H., Kouchi, Z., Kinouchi, T., Maeda, T., Sorimachi, H., Saido.T.C., Maruyama, K., Okuyama, A., Suzuki, K., Ishiura, S.
    • Journal Title

      Cytotechnology 33

      Pages: 213-219

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13210027
  • [Presentation] 野生型および変異型(ポリアラニン伸長型)Sox3の神経発生における機能解析2015

    • Author(s)
      大間 陽子, 高橋 秀治, 渡邊 ゆり, 石浦 章一, 小谷 典弘, 村越 隆之
    • Organizer
      第38回 日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-02
    • Data Source
      KAKENHI-PROJECT-25860844
  • [Presentation] グルタミン酸・グルタミンリピートの長さがタンパク質の安定性に与える影響2014

    • Author(s)
      中本千里菜, 大間陽子, 三橋弘明, 石浦章一
    • Organizer
      日本生化学会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2014-10-18
    • Data Source
      KAKENHI-PROJECT-25860844
  • 1.  SUZUKI Koichi (80011948)
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  • 2.  SORIMACHI Hiroyuki (10211327)
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  • 76.  星 美奈子
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  • 77.  ORIMO Satoshi
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  • 78.  ARIKAWA Eri
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  • 79.  有川 恵理
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  • 80.  織茂 智之
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  • 81.  RICHARD Isab
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  • 82.  安楽 治美
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  • 83.  ANRAKU Harumi
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  • 84.  KINO Yoshihiro
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  • 85.  TAKAHASHI Masanori
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