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YOKOSAWA Hideyoshi  横沢 英良

ORCIDConnect your ORCID iD *help
… Alternative Names

横沢 英良  ヨコザワ ヒデヨシ

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Researcher Number 90012765
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2015: 愛知学院大学, 薬学部, 教授
2012: 愛知学院大学, 薬学部, 教授
2007: 北海道大学, 大学院・薬学研究院, 教授
2006: 北海道大学, 大学院薬学研究院, 教授
1998 – 2005: 北海道大学, 大学院・薬学研究科, 教授 … More
2001 – 2003: 北海道大学, 大学院・薬学系研究科, 教授
1990 – 1997: School of Pharmacy, Hokkaido University, Professor, 薬学部, 教授
1989: 北海道大学, 薬学部, 助教授
1986 – 1987: 北海道大学, 薬学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / Functional biochemistry / Developmental biology / Biological Sciences / Cell biology / Structural biochemistry
Except Principal Investigator
Structural biochemistry / Science and Engineering / Natural medicines / General fisheries … More / Biological Sciences / Living organism molecular science / General medical chemistry / 動物発生・生理学 / 広領域 / Molecular biology Less
Keywords
Principal Investigator
ユビキチン / プロテアソーム / 受精 / 細胞周期 / ユビキチン様蛋白質 / プロテアーゼ / LHRH / 卵成熟 / 発生 / ユビキチンレセプター … More / 蛋白分解 / 転写因子 / 癌遺伝子 / 癌抑制遺伝子 / ユビキチンリガーゼ / 神経ペプチド / ダイノルフィン / P物質 / Fertilization / Development / Proteasome / 出芽酵母 / ubiquitin / proteasome / budding yeast / 減数分裂 / 細胞分裂 / G蛋白質 / Rho蛋白質 / チロシンリン酸化 / チロシンキナーゼ / 卵黄膜 / SUMO / ストレス応答 / 脱ユビキチン化 / ユビキチンワールド / 細胞増殖抑制因子 / F-box蛋白質 / 癌抑制因子 / SUMO-1 / システインプロテアーゼ / セリンプロテアーゼ / ホヤ類 / ライシン / 高分子量多機能プロテアーゼ / カルモジュリン / GTP結合蛋白質 / ホルボールエステル / 卵膜 / 脳内プロテア-ゼ / ソマトスタチン / Neuropeptidase / Neuroptetide / Substance p / Dynorphin / Somatostatin / GTP-結合蛋白質 / アネキシン / グルコシダーゼ / プロテア-ゼ / プロテアソ-ム / GTPー結合蛋白質 / リポコルチン / グルコシダ-ゼ / GTP-binding protein / 分子認識 / 発生・分化 / Ubiquitin / Protease / Molecular recognition / Cell cycle / Oocyte maturation / cell cycle / 増殖 / 制御サブユニット / growth / regulatory subunit / ubiquitin receptor / 翻訳後修飾 / ペプチドマスフィンガーブリント法 / ポリユビキチン鎖 / ペプチドマスフィンガープリント法 / ポリユビキチン類 / プロテオミクス / UFD経路 / post-translational modification / peptide mass fingerprinting / polyubiquitin chain / ubiquitin-like protein … More
Except Principal Investigator
プロテアソーム / ユビキチン / プロテアーゼ / p53 / 海洋生物 / 抗がん剤 / バイオモジュレーター / カルパイン / カテプシン / オートファジー / リソソーム / 蛋白分解 / 海洋由来微生物 / RPN7 / RPN5 / Fish Pathogen / Listonella anguillara / Metallo protease / Substrate specificity / Anticoagulation / Activated protein C / バイオモジュレータ / 蛋白質分解 / モディファイアー蛋白 / モディファイアー蛋白質 / 基質蛋白質の選別 / ホームページ / ユビキチン活性化酵素 / ユビキチンリガーゼ / Hdm2 / ユビキチン依存的タンパク質分解系 / 海洋無脊椎生物 / 細胞毒性 / タンパク質分解系 / がん抑制遺伝子産物 / 天然低分子化合物 / がん治療薬 / 海洋無脊椎動物 / プロテアソ-ム / 多機能プロテア-ゼ / 多成分複合体 / 構造解析 / 高分子量プロテア-ゼ / 分子遺伝学 / 多機能プロテア-ゼ複合体 / 細胞内プロテア-ゼ / 20S環状粒子 / cDNAクロ-ニング / 発生と分化 / Proteasomes / Multicatalytic protease / Structural analysis / Multisubunit complex / High molecular weight protease / 卵外被 / 卵(黄)膜ライシン / 孵化酵素 / 受精 / 孵化 / タンパク質の構造 / 卵膜硬化 / 卵膜タンパク質 / プロテオソ-ム / 卵膜 / 受精膜 / プロテア-ゼ / Egg envelope / Vitelline coat lysin / Hatching enzyme / Fertilization / Hatching / Protein structure / Proteasome / Hardening of egg envelope / ホヤ / アロ認識機構 / 機能発現 / 金属濃縮 / バナジウム / タンパク質 / 金属イオン / 濃縮 / ホヤの血球 / 組織特異性 / 金属濃縮機構 / Marine organisms / Ascidians / Alloreognition / Expression of functions / Accumulation of metals / Vanadium / Proteins / 蛋白連結システム / アポトーシス / カスパーゼ / 細胞周期 / 細胞分化 / 細胞死 / 自食作用 / カルパスタチン / 細胞文化 / 恒常性の維持 / BIOMODULATOR / PROTEOLYSIS / LYSOSOME / AUTOPHAGY / CONJUGATION SYSTEM / CATHEPSIN / APOPTOSIS / CASPASE / 26Sプロテアソーム / 出芽酵母 / ポリユビキチンSicI / 19S調節因子 / Nob1 / Pno1 / 核移行 / Rpn7 / 26S proteasome / budding yeast / polyubiguitinated SicI / ユビキチン結合酵素E2 / UBE2S / Ubc13 / ユビキチン修飾系 / E2 / 免疫プロテアソーム / 自己免疫疾患 / 創薬 / 天然資源 / ユビキチンープロテアソームシステム Less
  • Research Projects

    (28 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (46 People)
  •  Search for specific inhibitors of the ubiquitin-conjugating enzyme E2

    • Principal Investigator
      Tsukamoto Sachiko
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Natural medicines
    • Research Institution
      Kumamoto University
  •  Search for drug leads of autoimmune disease targeting the immunoproteasome

    • Principal Investigator
      Tsukamoto Sachiko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Natural medicines
    • Research Institution
      Kumamoto University
  •  Search for Natural Products which Enhance the Function of TumorSuppressor Protein and Study of the Mechanisms of Effects

    • Principal Investigator
      TSUKAMOTO Sachiko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Kumamoto University
  •  ユビキチン依存的タンパク質分解系に作用する低分子化合物の海洋資源からの探索

    • Principal Investigator
      塚本 佐知子
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Kanazawa University
  •  ユビキチン依存的タンパク質分解系を標的とする海洋生物由来の新規化合物の探索

    • Principal Investigator
      TSUKAMOTO Sachiko
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Kanazawa University
  •  Proteomic analysis of ubiquitin modificationPrincipal Investigator

    • Principal Investigator
      YOKOSAWA Hideyoshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  ユビキチン化修飾を司る癌関運遺伝子の探索Principal Investigator

    • Principal Investigator
      横沢 英良
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  Genetic and biochemical dissection of the 26S proteasomes

    • Principal Investigator
      AKIO Toh-c
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Molecular biology
    • Research Institution
      The University of Tokyo
  •  蛋白質分解-新しいモディフアイアー蛋白質による制御

    • Principal Investigator
      木南 英紀
    • Project Period (FY)
      2000 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Juntendo University
  •  受精機構におけるユビキチン-プロテアソームシステムPrincipal Investigator

    • Principal Investigator
      横沢 英良
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  ユビキチン依存的蛋白分解を指標とする癌関連遺伝子の探索Principal Investigator

    • Principal Investigator
      横沢 英良
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  ユビキチンワールド:新しい生体反応制御システムPrincipal Investigator

    • Principal Investigator
      横沢 英良
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Hokkaido University
  •  REGULATORY MECHANISMS OF THE 26S PROTEASOME ASSEMBLYPrincipal Investigator

    • Principal Investigator
      YOKOSAWA Hideyoshi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  受精のシグナル伝達におけるRho蛋白質の位置づけPrincipal Investigator

    • Principal Investigator
      横沢 英良
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Developmental biology
    • Research Institution
      Hokkaido University
  •  BIOMODULATOR FUNCTIONS OF PROTEOLYSIS

    • Principal Investigator
      KOMINAMI Eiki
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      JUNTENDO UNIVERITY
  •  Regulation of cell cycle progression by the ubiquitin-proteasome systemPrincipal Investigator

    • Principal Investigator
      YOKOSAWA Hideyoshi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  減数分裂に関与するプロテアーゼの作用機構Principal Investigator

    • Principal Investigator
      横沢 英良
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  バイオモジュレーターとしてのプロテアーゼ

    • Principal Investigator
      鈴木 紘一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo
  •  バイオモジュレーターとしてのプロテアーゼ

    • Principal Investigator
      SUZUKI Koichi
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo
  •  魚病細菌Listonella anguillaraのプロテイナーゼの新しい機能

    • Principal Investigator
      鈴木 聡
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General fisheries
    • Research Institution
      Kochi University
  •  Co-operative Research on Differentiation and Functional Expression of Blood Cells in Ascidiar

    • Principal Investigator
      MICHIBATA Hitoshi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      広領域
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Mechanisms of molecular recognition and cell cycle control in ubiquitin-proteasome systemPrincipal Investigator

    • Principal Investigator
      YOKOSAWA Hideyoshi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Hokkaido University, Faculty of Pharm.Sci.
  •  Study on regulatory factors involved in fertilization and developmentPrincipal Investigator

    • Principal Investigator
      YOKOSAWA Hideyoshi
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  Mechanism of Egg Envelope Dissolution-Action of the vitelline Coat Lysin and the Hatching Enzyme

    • Principal Investigator
      YAMAGAMI Kenjirou
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      動物発生・生理学
    • Research Institution
      Faculty of Science and Technology, Sophia University
  •  Structure and Cell Biology of a Novel Multicatalytic Proteinase Complex

    • Principal Investigator
      ICHIHARA Akira
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokushima
  •  Study on Physiological Roles of NeuropeptidasesPrincipal Investigator

    • Principal Investigator
      YOKOSAWA Hideyoshi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  受精に関与する配偶子プロテアーゼの生化学的・生理学的研究Principal Investigator

    • Principal Investigator
      横沢 英良
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  神経ペプチドの生成と分解に関与する脳内プロテアーゼの研究Principal Investigator

    • Principal Investigator
      横沢 英良
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University

All 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

  • [Journal Article] Niphateolide A, Isolation from the marine sponge Niphates olemda and determination of its absolute configuration by an ECD analysis2015

    • Author(s)
      H. Kato, T. Nehira, K. Matsuo, T. Kawabata, Y. Kobashigawa, H. Morioka, F. Losung, R. E. P. Mangindaan, N. J. de Voogd, H. Yokosawa, S. Tsukamoto
    • Journal Title

      Tetrahedron

      Volume: 71 Pages: 6956-6960

    • DOI

      10.1016/j.tet.2015.07.009

    • NAID

      120006897988

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07028, KAKENHI-PROJECT-26660093, KAKENHI-PROJECT-26860067, KAKENHI-PROJECT-25293025, KAKENHI-PROJECT-26305005
  • [Journal Article] Strongylophorines, meroditerpenoids from the marine sponge Petrosia corticata, function as proteasome inhibitors2015

    • Author(s)
      A. Noda, E. Sakai, H. Kato, F. Losung, R. E. P. Mangindaan, N. J. de Voogd, H. Yokosawa, S. Tsukamoto
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: 25

    • NAID

      120006897981

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293025
  • [Journal Article] Acantholactam and Pre-neo-kauluamine, Manzamine-Related Alkaloids from the Indonesian Marine Sponge Acanthostrongylophora ingens.2014

    • Author(s)
      A. H. El-Desoky, H. Kato, K. Eguchi, T. Kawabata, Y. Fujiwara, F. Losung, R. E. P. Mangindaan, N. J. de Voogd, M. Takeya, H. Yokosawa, S. Tsukamoto
    • Journal Title

      Journal of natural products

      Volume: 77 Pages: 1536-1540

    • DOI

      10.1021/np500290a

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293025, KAKENHI-PROJECT-25293089, KAKENHI-PROJECT-25860501, KAKENHI-PROJECT-26305005, KAKENHI-PROJECT-26860067
  • [Journal Article] 1-Hydroxyethylhalenaquinone: a new proteasome inhibitor from the marine sponge Xestospongia sp.2014

    • Author(s)
      M. Yamakuma, H. Kato, K. Matsuo, A. H. El-Desoky, T. Kawabata, F. Losung, R. E. P. Mangindaan, N. J. de Voogd, H. Yokosawa, S. Tsukamoto
    • Journal Title

      Heterocycles

      Volume: 89 Pages: 2605-2610

    • DOI

      10.3987/com-14-13087

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293025, KAKENHI-PROJECT-26305005, KAKENHI-PROJECT-26860067
  • [Journal Article] Halenaquinone inhibits RANKL-induced osteoclastogenesis.2014

    • Author(s)
      S. Tsukamoto, T. Takeuchi, T. Kawabata, H. Kato, M. Yamakuma, K. Matsuo, A. H. El-Desoky, F. Losung, R. E. P. Mangindaan, N. J. de Voogd, Y. Arata, H. Yokosawa.
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: 24 Pages: 5315-5317

    • DOI

      10.1016/j.bmcl.2014.09.043

    • NAID

      120006897978

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293025, KAKENHI-PROJECT-26305005
  • [Journal Article] Variabines A and B, new β-carboline alkaloids from the marine sponge Luffariella variabilis.2014

    • Author(s)
      E. Sakai, H. Kato, H. Rotinsulu, F. Losung, R. E. P. Mangindaan, N. J. de Voogd, H. Yokosawa, S. Tsukamoto
    • Journal Title

      J. Nat. Med.

      Volume: 68 Pages: 215-219

    • NAID

      120006897985

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293025
  • [Journal Article] Acanthomanzamines A-E with unprecedented manzamine frameworks from the marine sponge Acanthostrongylophora ingens2014

    • Author(s)
      A. Furusato, H. Kato, T. Nehira, K. Eguchi, T. Kawabata, Y. Fujiwara, F. Losung, R. E. P. Mangindaan, N. J. de Voogd, M. Takeya, H. Yokosawa, S. Tsukamoto
    • Journal Title

      Organic letters

      Volume: 16 Pages: 3888-3891

    • DOI

      10.1021/ol5015569

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293025, KAKENHI-PROJECT-25410044, KAKENHI-PROJECT-25860501, KAKENHI-PROJECT-26305005, KAKENHI-PROJECT-26660093, KAKENHI-PROJECT-26860067
  • [Journal Article] Spongiacidin C, a bromopyrrole alkaloid from the marine sponge Stylissa massa, functions as a USP7 inhibitor.2013

    • Author(s)
      M.Yamaguchi, R.E.P.Mangindaan, S.Tsukamoto
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: 23 Pages: 3884-3886

    • DOI

      10.1016/j.bmcl.2013.04.066

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22406001, KAKENHI-PUBLICLY-25108719, KAKENHI-PROJECT-25293025
  • [Journal Article] Siladenoserinols A-L: NewSulfonated Serinol Derivatives from aTunicate as Inhibitors of p53-Hdm2Interaction2013

    • Author(s)
      H. Yokosawa, S. Tsukamoto
    • Journal Title

      Org. Lett

      Volume: 15 Pages: 322-325

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310138
  • [Journal Article] Siladenoserinols A-L : new sulfonated serinol derivatives from a tunicate as inhibitors of p53-Hdm2 interaction2013

    • Author(s)
      Nakamura, Y.
    • Journal Title

      Org. Lett.

      Volume: 15 Pages: 322-325

    • DOI

      10.1021/ol3032363

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310138, KAKENHI-PROJECT-22406001, KAKENHI-PUBLICLY-25108719, KAKENHI-PROJECT-25293025
  • [Journal Article] Manadosterols A and B, SulfonatedSterol Dimers Inhibiting Ubc13-Uev1AInteraction, Isolated from the MarineSponge Lissodendryx fibrosa2012

    • Author(s)
      H. Yokosawa, S. Tsukamoto
    • Journal Title

      J. Nat. Prod.

      Volume: 75 Pages: 1495-1499

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310138
  • [Journal Article] Hirtioreticulines A-E, IndoleAlkaloids Inhibiting the Ubiquitinactivating Enzyme, from the Marine SpongeHyrtios reticulatus2012

    • Author(s)
      H. Yokosawa, S. Tsukamoto
    • Journal Title

      Bioorg. Med. Chem

      Volume: 20 Pages: 4437-4442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310138
  • [Journal Article] ユビキチン修飾系を標的とする創薬シーズの探索(総説).2012

    • Author(s)
      塚本佐知子、横沢英良
    • Journal Title

      実験医学・増刊「シグナル伝達 研究最前線2012」

      Volume: 30 Pages: 171-176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310138
  • [Journal Article] ユビキチン依存的タンパク質分解系を標的とする創薬 (総説)2011

    • Author(s)
      塚本佐知子、横沢英良
    • Journal Title

      化学と生物

      Volume: 49 Pages: 745-754

    • Data Source
      KAKENHI-PROJECT-22310138
  • [Journal Article] Isolation of Salsolinol, aTetrahydroisoquinoline Alkaloid, from theMarine Sponge Xestospongia cf. vansoestias a Proteasome Inhibitor2011

    • Author(s)
      H. Yokosawa, S. Tsukamoto(
    • Journal Title

      Chem. Pharm.Bull

      Volume: 59 Pages: 287-290

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310138
  • [Journal Article] タンパク質分解の不思議:ユビキチン‐プロテアソームシステムの仕組みと創薬(総説)2010

    • Author(s)
      塚本佐知子、横沢英良
    • Journal Title

      愛知学院大学薬学会誌

      Volume: 3 Pages: 1-18

    • Data Source
      KAKENHI-PROJECT-22310138
  • [Journal Article] Aaptamine, an Alkaloid from theSponge Aaptos suberitoides, Functions asa Proteasome Inhibitor2010

    • Author(s)
      S. Tsukamoto, H. Yokosawa
    • Journal Title

      Bioorg. Med. Chem.Lett

      Volume: 20 Pages: 3341-3343

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310138
  • [Journal Article] Inhibition ofthe Ubiquitin-proteasome System byNatural Products for Cancer Therapy(Review)2010

    • Author(s)
      S. Tsukamoto, H. Yokosawa
    • Journal Title

      Planta Med

      Volume: 76 Pages: 1064-1074

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310138
  • [Journal Article] Variabines A and B, New -CarbolineAlkaloids from the Marine SpongeLuffariella variabilis

    • Author(s)
      H. Yokosawa, S. Tsukamoto
    • Journal Title

      J. Nat. Med

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310138
  • [Journal Article] Spongiacidin C, a BromopyrroleAlkaloid from the Marine Sponge Stylissamassa, Functions as a USP7 Inhibitor

    • Author(s)
      H. Yokosawa, S. Tsukamoto
    • Journal Title

      Bioorg. Med. Chem. Lett

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310138
  • [Presentation] ユビキチン-プロテアソームシステムに対する阻害剤の開発2014

    • Author(s)
      塚本佐知子、横沢英良
    • Organizer
      第19回日本病態プロテアーゼ学会 学術集会シンポジウム「ユビキチンとプロテアソーム研究の最前線」
    • Place of Presentation
      大阪(千里ライフサイエンスセンター)
    • Year and Date
      2014-08-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293025
  • 1.  KOMINAMI Eiki (10035496)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  TSUKAMOTO Sachiko (40192190)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 21 results
  • 3.  SUZUKI Koichi (80011948)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  SAWADA Hitoshi (60158946)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  NATORI Shunji (50012662)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  TANAKA Keiji (10108871)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  HOSHI M (20012411)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  WASHIMA Seiichika (60008571)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  ISHIURA Shoichi (10158743)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  ISHIKAWA Katsutoshi (00008608)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  ICHIHARA Akira (40035374)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SASAKI Makoto (10080003)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  IKAI Atsushi (50011713)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  YAMAGAMI Kenjirou (50011474)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  NOMURA K (30073026)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  IUCHI I (10011694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  FUKUSHIMA Kazu (70087138)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SAGATA Noriyuki (80142024)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  SENO Takashi (30076989)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  MICHIBATA Hitoshi (00111740)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  KAWAMURA Kazuo (30136361)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  SAITOH Yasunori (00196015)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  UCHIYAMA Yasuo (10049091)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  OHSUMI Yoshinori (30114416)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  AKIO Toh-c (90029249)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  鈴木 聡 (90196816)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  楠田 理一 (90036715)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  木戸 博 (50144978)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  中西 重忠 (20089105)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  水野 義邦 (30049043)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  川原 裕之 (70291151)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  山尾 文明 (10158074)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  小南 欽一郎 (80304830)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  岩井 一宏 (60252459)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  安田 秀世 (40111554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  千葉 智樹 (00311423)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  村地 孝 (10089104)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  西田 宏記 (60192689)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  佐藤 矩行 (30025481)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  三浦 正幸 (50202338)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  FUJIWARA Yukio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 42.  KAYO Hikaru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 43.  竹屋 元裕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  川畑 哲郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 45.  松尾 光一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  根平 達夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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