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ICHIHARA Akira  市原 明

ORCIDConnect your ORCID iD *help
… Alternative Names

MURAYAMA Akira

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Researcher Number 40035374
External Links
Affiliation (based on the past Project Information) *help 1987 – 1993: 徳島大学, 酵素科学研究センター, 教授
1991: 徳島大学, 酵素研究所, 教授
1991: 徳島大学, 酵素科学研究所, 教授
1990: Inst. for Enz. Sci., Univ. of Tokushima, Professor, 酸素科学研究センター, 教授
1989 – 1990: 徳島大学, 酵素センター, 教授 … More
1989: Institute for Enzyme Research, University of Tokushima, Professor, 教授
1986: Tokyo Metropolitan Inst. of Med. Sci., Chief Researcher
1986: 徳島大, 医学部, 教授
1986: Univ. of Tokushima, School of Medicine, Professor, 医学部, 教授
1986: Institute for Enzyme Research Tokushima University, 酵素科学センター, 教授 Less
Review Section/Research Field
Principal Investigator
Pathological medical chemistry / General medical chemistry
Except Principal Investigator
Pathological medical chemistry / 医学一般 / Legal medicine / General medical chemistry / Biological pharmacy
Keywords
Principal Investigator
増殖因子 / 肝細胞 / 増殖抑制因子 / 初代培養 / プロテアソ-ム / 多機能プロテア-ゼ複合体 / インターロイキン / 分化 / 細胞膜調節因子 / 初代培養肝細胞 … More / 肝再生 / 細胞周期 / 細胞接触 / ユビキチン / プロテアソーム / Phorbol ester(TPA) / cAMP / Interleukin-1beta / Transforming growth factor(TGF)-beta / Cell contact / Primary culture / Growth factors / Hepatocytes / 組織構築 / 細胞分化 / 細胞増殖因子 / 増殖と機能 / 肝細胞培養 / 肝組織 / 混合培養 / 細胞膜 / DNA合成 / 細胞間相互作用 / 増殖 / ホルボ-ルエステル / cyclic AMP / Interleukin(IL-1) / Transfoming Growth Factor(TGF-beta) / ホルボル・エステル(TPA) / CAMP / Interleukin-1β / Transforming growth factor(TGF)-β / MHC classI-restricted antigen presentation / Gamma-interferon / Supramolecular complex / Antigen Processing / Cell cycle / Energy-dependent proteolysis / Ubiquitin / Proteasome / 細胞増殖・分化 / エネルギ-依存性分子識別 / 蛋白質超分子複合体 / エネルギー依存性分子識別 / 分子適合 / 抗原プロセシング・提示 / 細胞内蛋白質分解機構 / 遺伝子転写制御機構 / 多機能プロテアーゼ複合体 / MHCクラスI拘束性抗原提示 / エネルギー依存性蛋白分解 / MHCクラスエ拘束性抗原提示 / 抗原プロセシング / ガンマ型インターフェロン / 超分子複合体 / エネルギー依存性蛋白質分解 / High molecular weight protease / Multisubunit complex / Structural analysis / Multicatalytic protease / Proteasomes / 発生と分化 / cDNAクロ-ニング / 20S環状粒子 / 細胞内プロテア-ゼ / 分子遺伝学 / 高分子量プロテア-ゼ / 構造解析 / 多成分複合体 / 多機能プロテア-ゼ / 肝癌細胞 / TGF-β / 血小板 / 細胞増殖調節 / 前癌状態 / 過形成腫粒 / 肝細胞の増殖と分化 / 肝臓機能 / クロマチン / 転写因子 / 調節領域 / 遺伝子 / ホルモン / 遺伝子破壊 / 癌胎児性蛋白 / 蛋白分解酵素 / 生物工学 / 遺伝子操作 / ツメガエル卵の発現系 / 肝細胞の初代培養 / 卵母細胞 / マイクロインジェクション / ヒト単球 / 細胞工学 / 発現ベクタ- / 増殖制御因子 / 高脂血症 / 糖新生 / 遺伝子発現 / 活性型ビタミンD / サイクリックAMP / インスリン / グルカゴン / ステロイドホルモン / 蛋白復合体 / 白血病細胞 / 異常発現 / 細胞増殖 / がん細胞 / 多機能プロテアーゼ … More
Except Principal Investigator
細胞核 / 細胞膜 / Cytoplasmic factors / Endoplasmic reticulum / Lysosomes / Cell nucleus / Cell membrane / Organella / Metabolic regulation / Cellular responses / 情報伝達 / リソソーム / 代謝制御機構 / 細胞質因子 / 小胞体 / リソソ-ム / オルガネラ / 代謝制御 / 薬物応答 / Tumor Growth Stimulating Activity (TGSA) / Platelet-Derived Growth Inhibitor (PDGI) / Insulin-Stimulating Peptide (ISP) / Erythropoietin-like factor / Fibroblast-derived Endothelial Cell Growth Factor (f-ECGF) / Cartilage-derived Anti-Tumor Factor (CATF) / Cartilage-Derived Factor (CDF) / Bリンパ球分化因子 / 腫瘍増殖促進因子 / 血小板由来増殖阻害因子 / インスリン作用促進因子 / エリスロポエチン様因子 / 線維芽細胞由来内皮細胞増殖因子 / 軟骨由来抗腫瘍因子 / 軟骨由来因子 / Progesterone / Estrogen / Testosterone / Glucocorticoid / Steroid Hormone Receptor / ステロイドホルモンレセプター / 遺伝子発現調節レセプター / ステロイド・ホルモン作用機構 / ステロイド・ホルモン / G protein / gene regulation / transduction / cell nucleus / cytoplasm / cell membrane / receptors / drugs / organella constituents / m‐RNA構造 / 細胞膜タンパク質 / 膜結合性Gキナ-ゼ / ホルモン受容体 / 脂質輸送 / 細胞膜因子 / Cキナーゼ / Gタンパク質 / 遺伝子調節 / トランスダクション / 細胞質 / 受容体 / 薬物 / オルガネラ構成因子 / Antigen presentation / Intracellular protease transport / Amyloidogenic protease / Calpain activation due to inafarotion / Hematocyte coagulation factor / Thrombomodulin / 94K calpain / Limited proteolysis / ニュ-カッスル病ウイルス / 26Sプロテアソ-ム / T細胞エイズレセプタ- / カルパインペプチドの白血球遊走活性 / カルパインの活性化 / プレプロタキキニン遺伝子発現調節因子 / プロテア-ゼによる情報発現 / トランスゴルジ膜結合性プロセシングプロテアーゼ / カテプシンBの抗原阻囎への関与 / 心筋梗塞巣活性化カルパイン / プロガストリンの活性化 / 筋組織特異的カルパイン / カテプシン-インバリアント鎖による抗原提示の調節 / 筋組織特異的94Kカルバイン / カテプシンの抗原提示への関与 / カテプシンの細胞内選別輸送 / アミロイドジェニックプロテアーゼ / 脳梗塞巣活性化カルパイン / 血球内凝固因子 / スロンボモジュリンの発現調節 / 筋組織特異的94Kカルパイン / プロテアーゼによる情報発現 / リン脂質合成欠損変異 / 蛙卵によるmRNAの選別 / 筋原細胞の融合 / 赤血球ゴースト法 / 高物子物質注入 / ペプチド合成 / 細胞操作 / 遺伝子操作 Less
  • Research Projects

    (19 results)
  • Co-Researchers

    (49 People)
  •  Studies on structure and the biological functions of a large multi-molecular complex "the proteasome"Principal Investigator

    • Principal Investigator
      ICHIHARA Akira
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      Institute for Enzyme Research, The University of Tokushima
  •  Roles of proteases in signal transduction and their disorders

    • Principal Investigator
      SASAKI Makoto
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Nagoys City Unversity Medcal School
  •  Co-operative Responses of Organella Constituents to Drug stimulation

    • Principal Investigator
      OHBA Yoshiki
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kanazawa University
  •  プロテアソ-ム(巨大蛋白分解酵素復合体)の構造解析と癌化における発現異常の解明Principal Investigator

    • Principal Investigator
      市原 明
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokushima
  •  ホルモンによる遺伝子発現調節および病態に関する研究Principal Investigator

    • Principal Investigator
      市原 明
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokushima
  •  培養肝細胞を用いた機能と増殖を調節する肝組織構築の生化学的研究Principal Investigator

    • Principal Investigator
      市原 明
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokushima
  •  多機能プロテアーゼ復合体(プロテアソーム)の機能と癌化における異常発現機構の解析Principal Investigator

    • Principal Investigator
      市原 明
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokushima
  •  ホルモンによる遺伝子発現調節および病態に関する研究Principal Investigator

    • Principal Investigator
      市原 明
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokushima
  •  肝細胞増殖制御因子の生物工学的技法による同定,遺伝子構造解析と大量生産のシステム化Principal Investigator

    • Principal Investigator
      市原 明
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokushima
  •  Structure and Cell Biology of a Novel Multicatalytic Proteinase ComplexPrincipal Investigator

    • Principal Investigator
      ICHIHARA Akira
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokushima
  •  培養肝細胞を用いた増殖と分化の制御機構の研究Principal Investigator

    • Principal Investigator
      市原 明
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokushima
  •  Analysis of Functional Cooperations between Organella in Responses to Medicines

    • Principal Investigator
      ISHIBASHI Sadahiko.
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Legal medicine
    • Research Institution
      Hiroshima University
  •  培養肝細胞を用いた増殖と分化の制御機構の研究Principal Investigator

    • Principal Investigator
      市原 明
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokushima
  •  細胞工学的手法によるヒトを含む高等動物細胞の体細胞遺伝生理学的研究

    • Principal Investigator
      岡田 善雄
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      医学一般
    • Research Institution
      Osaka University
  •  培養肝細胞を用いた増殖と分化の制御機構の研究Principal Investigator

    • Principal Investigator
      市原 明
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokushima
  •  細胞工学的手法によるヒトを含む高等動物細胞の遺伝生理学的研究

    • Principal Investigator
      岡田 善雄
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      医学一般
    • Research Institution
      Osaka University
  •  Biochemical studies on tissue architecture of liver, which controls functions and growth, using primary cultured hepatocytesPrincipal Investigator

    • Principal Investigator
      ICHIHARA Akira
    • Project Period (FY)
      1986 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Tokushima
  •  Molecular Mechanism of Steroid Hormone Action and Modulation of Gene Expression

    • Principal Investigator
      SAKAMOTO Yukiya
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University
  •  Reaction mechanisms of various growth regulators and differentiation regulators and their clinical applications

    • Principal Investigator
      SUZUKI Fujio
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  • 1.  TANAKA Keiji (10108871)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 2.  TOMITA Yumiko (00089913)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 3.  NODA Chiseko (40035506)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 4.  OHBA Yoshiki (10012634)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  中村 敏一 (00049397)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  ISHIBASHI Sadahiko (90012616)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  NATORI Shunji (50012662)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  谷口 維紹 (50133616)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  SASAKI Makoto (10080003)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  ICHIKAWA Atsushi (10025695)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  NOMURA Yasuyuki (00034041)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  森 正敬 (40009650)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  市山 新 (90025601)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  岡田 善雄 (30029756)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  田代 裕 (40077558)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  内田 驍 (40029781)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  松原 謙一 (20037394)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  新垣 理恵子 (00193061)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  YOKOSAWA Hideyoshi (90012765)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  ISHIURA Shoichi (10158743)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  IKAI Atsushi (50011713)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  YOSHIMURA Tetsuro (30035472)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  OHKUBO Iwao (80152073)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  IWANAGA Sadaaki (90029942)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  SUZUKI Koichi (80011948)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  KATUNUMA Nobuhiko (50035375)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  OKAMOTO Hiroshi (60025632)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  SAKAMOTO Yukiya (60028280)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  ENDO Hiroyoshi (50012604)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  OTA Minoru (70048255)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  ICHII Shogo (80032150)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  SUZUKI Fujio (40028717)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  KISHIMOTO Tadamitsu (10093402)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  TAKEDA Yoshiro (00028705)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  TAKAKU Fumimaro (40048955)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  KATO Keitaro (70037571)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  尾形 悦郎 (70013761)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  田中 武彦 (60028272)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  藤井 義明 (00098146)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  井村 裕夫 (10025570)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  黒木 登志夫 (90006073)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  石川 勝利 (00008608)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  村地 孝 (10089104)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  高橋 健治 (70011533)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  木南 英紀 (10035496)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  村山 昭 (10109952)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  佐藤 威 (80125567)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  赤松 穣 (00072900)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  YAMANE Isao
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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