Tsukamoto Nobuo 塚本信夫

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TSUKAMOTO Nobuo 塚本信夫

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Researcher Number	20407117
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 特任研究員
Affiliation (based on the past Project Information) *help	2023: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 特任研究員 2016 – 2020: 慶應義塾大学, 医学部(信濃町), 助教 2007 – 2015: Keio University, School of Medicine, Instructor 2009: 医学部, 助教 2006: 慶應義塾大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Tumor therapeutics / Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor immunology / Digestive surgery Except Principal Investigator Dermatology / Digestive surgery / Tumor immunology / Biological Sciences
Keywords	Principal Investigator 腫瘍免疫 / 免疫抑制 / IDO / AhR / 併用免疫療法 / 代謝 / berberine / がん免疫療法 / がん微小環境 / TDO2 … More / IDO1 / TDO / がん免疫治療 / Kynurenine / BDCA2 / NKp44 / ILT7 / プラズマ細胞様樹状細胞 / 早期診断 / 腫瘍マーカー / 腫瘍抗原 / 小腸大腸肛門外科学 … More Except Principal Investigator 免疫抑制 / 樹状細胞 / 悪性黒色腫 / 免疫療法 / 腫瘍抗原 / Snail / がん免疫療法 / 消化器癌 / RNA干渉 / 上皮間葉転換 / immunosuppression / gastroenterogic cancer / epithelial-mesenchymal transition / 免疫応答 / コルポスコピー / 細胞診 / 子宮頸癌 / ラマン分光 / 上皮-間葉転換 / 分子標的薬 / 免疫制御 / 分子標的治療薬 / 網羅的分子解析 / 生体内腫瘍破壊法 / エフェクター細胞 / 免疫抑制制御 / 免疫チェックポイント阻害 / T細胞 / メラノサイト / iPS / 皮膚科学 / 色素細胞 / 幹細胞 / iPS細胞 / シグナル伝達 / シグナル伝達異常 / 皮膚腫瘍学 / 癌遺伝子 / 膵癌 / シグナル伝達阻害 / 大腸癌 / DNAチップ / 免疫回避 / HLA遺伝子導入マウス / 網羅的遺伝子解析 / 転移 / 制御性T細胞 / 免疫抵抗性 / がん幹細胞 Less

Elucidation of the mechanism of antitumor immunity enhancing effects of berberine and development of effective combination immunotherapyPrincipal Investigator
- Principal Investigator
  
  Tsukamoto Nobuo
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Cancer Center Japan
  Keio University
Analysis of non-uniform immune-suppressive mechanisms in tumor microenvironment and development of effective anti-tumor immune therapiesPrincipal Investigator
- Principal Investigator
  
  Tsukamoto Nobuo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Keio University
Study on roles of aryl hydrocarbon receptor (AhR) in tumor microenvironment and estimation of AhR as a therapeutic target for cancer patientsPrincipal Investigator
- Principal Investigator
  
  Tsukamoto Nobuo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Keio University
Systematic analysis of cellular signaling involved in the melanoma induced immunosuppression
- Principal Investigator
  
  KAWAKAMI Yutaka
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Development of effective immunotherapy by combining interventions on key points in the anti-tumor immune network
- Principal Investigator
  
  KAWAKAMI Yutaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Tumor immunology
- Research Institution
  Keio University
Analysis of mechanisms for immunosuppression through ILT7/NKp44/BDCA2 ligands expressed on cancer cellsPrincipal Investigator
- Principal Investigator
  
  TSUKAMOTO Nobuo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor immunology
- Research Institution
  Keio University
Elucidation of the resistance mechanisms of immunotherapy by the abnormal signal transduction in melanoma and development of methods to overcome it
- Principal Investigator
  
  SAKURAI Toshiharu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
iPS細胞・間葉系幹細胞からの色素細胞と悪性黒色腫の作成と発現分子の臨床応用
- Principal Investigator
  
  河上裕
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Development of effective immunotherapy by combining methods to restore immunocompetence of cancer patients
- Principal Investigator
  
  KAWAKAMI Yutaka
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Keio University
Development of diagnostic method and immunotherapy using a novel molecule specifically expressed in colorectal carcinomasPrincipal Investigator
- Principal Investigator
  
  TSUKAMOTO Nobuo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Keio University
The study of immunosuppressive mechanisms induced by gastrointestinal cancer during epithelial-mesnchymal transition and clinical application of this target therapy
- Principal Investigator
  
  SAKURAI Toshiharu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Keio University
Development of immunotherapy based on the identification of tumor antigens
- Principal Investigator
  
  KAWAKAMI Yutaka
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University

[Book] Cancer Induced Immunosuppression and its Modulation by Signal Inhibitors in “Resistance of cancer cells to CTL-mediated immunotherapy” Eds: Chouaib S and Bonavida B,2015
- Author(s)
  Kawakami Y, Qian L, Kawamura N, Miyazaki J, Tsubota K, Kinoshita T, Nakaura K, Ohmura G, Satomi R, Sugiyama J, Nishio H, Hayakawa T, Popivanova B, Nuchsupha S, Liu TH, Kamijuku H, Kudo-Saito C, Tsukamoto N, Sakurai T, Fujita T, Yaguchi T.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25670506
[Book] Development of personalized combination cancer immunotherapy based on the patients’ immune status in “Inflammation and immunity in cancer ”　Eds:Tsukasa Seya, Keiko Udaka, Misako Matsumoto, Noriyuki Sato2015
- Author(s)
  Kawakami Y, Qian L, Kawamura N, Miyazaki J, Nagumo H, Tsubota K, Kinoshita T, Nakamura K, Ohmura G, Satomi R, Sugiyama J, Nishio H, Hayakawa T, Popivanova B, Nuchsupha S, Liu TH, Kamijuku H, Kudo-Saito C, Tsukamoto N, Sakurai T, Fujita T, Yaguchi T
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25430158
[Book] Development of personalized combination cancer immunotherapy based on the patients’ immune status in “Inflamamtion and immunity in cancer ” Eds:Tsukasa Seya, Keiko Udaka, Misako Matsumoto, Noriyuki Sato,2015
- Author(s)
  Kawakami Y, Qian L, Kawamura N, Miyazaki J, Nagumo H, Tsubota K, Kinoshita , Nakamura K, Ohmura G, Satomi R, Sugiyama J, Nishio H, Hayakawa T, Popivanova B, Nuchsupha S, Liu TH, Kamijuku H, Kudo-Saito C, Tsukamoto N, Sakurai T, Fujita T, Yaguchi T.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25670506
[Book] Roles of signaling pathways in cancer cells and immune cells in generation of immunosuppressive tumor associated microenvironments. in “The Tumor Immunoenvironment” Eds, Michael Shurin, Anatoli Malyguine, Viktor Umansky,2013
- Author(s)
  1. Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Kamijuku H, Tsujikawa T, Kawamura N.
- Publisher
  Springer Science.
- Data Source
  KAKENHI-PROJECT-25670506
[Book] Roles of signaling pathways in cancer cells and immune cells in generation of immunosuppressive tumor associated microenvironments. in "The Tumor Immunoenvironment" Eds, Shurin M, Malyguine A, Umansky V2013
- Author(s)
  Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Kamijuku H, Tsujikawa T, Kawamura N
- Publisher
  Springer Science
- Data Source
  KAKENHI-PROJECT-23240128
[Book] Roles of signaling pathways in cancer cells and immune cells in generation of immunosuppressive tumor associated microenvironments. in “The Tumor Immunoenvironment” Eds, Michael Shurin, Anatoli Malyguine, Viktor Umansky,2013
- Author(s)
  Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Kamijuku H, Tsujikawa T,Kawamura N
- Publisher
  Springer Science
- Data Source
  KAKENHI-PROJECT-23240128
[Book] Gene Therapy(Development of individualized immunotherapy based on the analysis on anti-tumor immune responses to the human tumor antigens identified using immunological and genetic methods)2009
- Author(s)
  Kawakami Y, Fujita T, Kudo C, Sakurai T, Udagawa M, Hasegawa G, Ishida A, Kitagawa Y, Tanabe M, Saito M, Izumi Y, Kawamura M, Yaguchi T, Ueda Y, Hayashi E, Wang Q, Tsukamoto N, Matsuzaki Y, Sumimoto H,Takeuchi H, Tanikawa A, Handa M, Amagai M, Kobayashi K, Ikeda Y, Azuma I, Kitajima M
- Data Source
  KAKENHI-PROJECT-17016070
[Journal Article] Immune-resistant mechanisms in cancer immunotherapy2020
- Author(s)
  Kawakami Y, Ohta S, Sayem MA, Tsukamoto N, Yaguchi T.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 25 Issue: 5 Pages: 810-817
- DOI
  10.1007/s10147-019-01611-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08309, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H03534, KAKENHI-PROJECT-19K07758
[Journal Article] CCL2 is critical for immunosuppression to promote cancer metastasis2013
- Author(s)
  Kudo-Saito C.
- Journal Title
  
  Clin Exp Metastasis
  
  Volume: 30 Issue: 4 Pages: 393-405
- DOI
  10.1007/s10585-012-9545-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501025, KAKENHI-PROJECT-23240128, KAKENHI-PROJECT-25430158
[Journal Article] CCL2 is critical for immunosuppression to promote cancer metastasis.2013
- Author(s)
  Kudo-Saito C, Shirako H, Ohike M, Tsukamoto N, Kawakami Y.
- Journal Title
  
  Clin Exp Metastasis
  
  Volume: 30 Pages: 393-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501025
[Journal Article] Cancer-induced immunosuppressive cascades and their reversal by molecular-targeted therapy.2013
- Author(s)
  Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Hoon Park J, Kamijuku H, Tsujikawa T, Kawamura N
- Journal Title
  
  Ann. N.Y. Acad. Sci.,
  
  Volume: 1284(1) Issue: 1 Pages: 80-86
- DOI
  10.1111/nyas.12094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240128, KAKENHI-PROJECT-25430158, KAKENHI-PROJECT-25462614, KAKENHI-PROJECT-25670506, KAKENHI-PROJECT-25830122
[Journal Article] Immunotherapy targeting cancer stem cells.2012
- Author(s)
  Kawakami Y, Matsushita M, Ueda R, Tsukamoto N, Ohta S.
- Journal Title
  
  Nihon Rinsho
  
  Volume: 70 Pages: 2142-6
- NAID
  40019493388
- Data Source
  KAKENHI-PROJECT-22501025
[Journal Article] Cancer-testis antigen BORIS is a novel prognostic marker for patients with esophageal cancer.2012
- Author(s)
  Okabayashi K, Fujita T, Miyazaki J, Okada T, Iwata T, Hirao N, Noji S, Tsukamoto N, Goshima N, Hasegawa H, Takeuchi H, Ueda M, Kitagawa Y, Kawakami Y.
- Journal Title
  
  Cancer Sci
  
  Volume: 103(9) Issue: 9 Pages: 1617-24
- DOI
  10.1111/j.1349-7006.2012.02355.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390263, KAKENHI-PROJECT-22501025, KAKENHI-PROJECT-22791544, KAKENHI-PROJECT-23240128, KAKENHI-PROJECT-23590908, KAKENHI-PROJECT-24592532
[Journal Article] Immune suppression and resistance mediated by constitutive activation of Wnt/β-catenin signaling in human melanoma cells2012
- Author(s)
  Yaguchi T.
- Journal Title
  
  J Immunol.
  
  Volume: 189 Issue: 5 Pages: 2110-2117
- DOI
  10.4049/jimmunol.1102282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501025, KAKENHI-PROJECT-23240128, KAKENHI-PROJECT-23659554, KAKENHI-PROJECT-23791293, KAKENHI-PROJECT-24501358, KAKENHI-PROJECT-24591635, KAKENHI-PROJECT-24592532
[Journal Article] Immune suppression and resistance mediated by constitutive activation of Wnt/β-catenin signaling in human melanoma cells.2012
- Author(s)
  Yaguchi T, Goto Y, Kido K, Mochimaru H, Sakurai T, Tsukamoto N, Kudo-Saito C, Fujita T, Sumimoto H, Kawakami Y.
- Journal Title
  
  J Immunol.
  
  Volume: 189 Pages: 2110-2117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501025
[Journal Article] Cancer-testis antigen BORIS is a novel prognostic marker for patients with esophageal cancer.2012
- Author(s)
  Okabayashi K, Fujita T, Miyazaki J, Okada T, Iwata T, Hirao N, Noji S, Tsukamoto N, Goshima N, Hasegawa H, Takeuchi H, Ueda M, Kitagawa Y, Kawakami Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 103 Pages: 1617-1624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501025
[Journal Article] The mechanisms of cancer immunoescape and development of overcoming strategies.2011
- Author(s)
  Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Ueda R, Iwata-Kajihara T, Nishio H, Kawamura N, Kawakami Y.
- Journal Title
  
  Int J Hematol.
  
  Volume: 93 Pages: 294-300
- NAID
  10029533724
- Data Source
  KAKENHI-PROJECT-22501025
[Journal Article]2011
- Author(s)
  Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Ueda R, Iwata-Kajihara T, Nishio H, Kawamura N, Kawakami Y
- Journal Title
  
  Int J Hematol
  
  Volume: Vol.93, No.3 Pages: 294-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591445
[Journal Article] 腫瘍免疫制御機構とその克服2009
- Author(s)
  河上裕、住本秀敏、工藤千恵、塚本信夫、桜井敏晴、植田良、谷口智憲、川村直、梶原知子
- Journal Title
  
  最新医学
  
  Volume: Vol.64、No.11
- Data Source
  KAKENHI-PROJECT-21591445
[Journal Article] Involvement of Hyaluronan and Its Receptor CD44 with Choroidal Neovascularization2009
- Author(s)
  Mochimaru H., Takahashi E., Tsukamoto N., Miyazaki J., Yaguchi T., Koto T., Kurihara T., Noda K., Ozawa Y., Ishimoto T., Kawakami Y., Tanihara H., Saya H., Ishida S., Tsubota K.
- Journal Title
  
  Invest Ophthalmol Vis Sci (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591562
[Journal Article] Impairment of pDC for IFN production by the ligand for immunoglobulin-like transcript 7(ILT7) expressed on human cancer cells2009
- Author(s)
  Tsukamoto N, Okada S, Onami Y, Sasaki Y, Umezawa K, Kawakami Y
- Journal Title
  
  Clin Cancer Res
  
  Volume: Vol.15, No.18 Pages: 5733-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591445
[Journal Article] Impairment of pDC for IFN production by the ligand forimmunoglobulin-like transcript 7 (ILT7) expressed on human cancer cells.2009
- Author(s)
  Tsukamoto N, et al.
- Journal Title
  
  Clin Cancer Res. 15(18)
  
  Pages: 5733-5743
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016070
[Journal Article] Impairment of pDC for IFN production by the ligand for immunoglobulin-like transcript 7 (ILT7) expressed on human cancer cells.2009
- Author(s)
  Tsukamoto N, Okada S, Onami Y, Sasaki Y, Umezawa K, Kawakami Y
- Journal Title
  
  Clin Cancer Res. 15(18)
  
  Pages: 5733-5743
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016070
[Journal Article] Dendritic cell based personalized immunotherapy based on cancer antigen research2008
- Author(s)
  Kawakami Y, Fujita T, Kudo C, Sakurai T, Udagawa M, Hasegawa G, Ishida A, Kitagawa Y, Tanabe M, Saito M, Izumi Y, Kawamura M, Yaguchi T, Ueda Y, Hayashi E, Wang Q, Okada S, Tsukamoto N, Matsuzaki Y, Sumimoto H, Takeuchi H, Tanikawa A, Handa M, Amagai M, Kobayashi K, Ikeda Y, Azuma I, Kitajima M.
- Journal Title
  
  Frontier in Bioscience 13
  
  Pages: 1952-1958
- Data Source
  KAKENHI-PROJECT-19591562
[Journal Article] Dendritic cell based personalized immunotherapy based on cancer antigen research2008
- Author(s)
  Kawakami Y, Fujita T, Kudo C, Sakurai T, Udagawa M, Yaguchi T, Hasegawa G, Hayashi E, Ueda Y, Iwata T, Wang Q, Okada S, Tsukamoto N, Matsuzaki Y, Sumimoto H.
- Journal Title
  
  Frontier in Bioscience 13
  
  Pages: 1952-1958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390355
[Journal Article] Development of individualized immunotherapy based on the analysis on anti-tumor immune responses to the human tumor antigens identified using immunological and genetic methods2007
- Author(s)
  Kawakami Y, Fujita T, Kudo C, Sakurai T, Udagawa M, Hasegawa G, Ishida A, Kitagawa Y, Tanabe M, Saito M, Izumi Y, Kawamura M, Yaguchi T, Ueda Y, Hayashi E, Wang Q, Tsukamoto N, Matsuzaki Y, Sumimoto H, Takeuchi H, Tanikawa A, Handa M, Amagai M, Kobayashi K, Ikeda Y, Azuma I, and Kitajima M.
- Journal Title
  
  Gene Therapy
  
  Pages: 240-248
- Data Source
  KAKENHI-PROJECT-19390355
[Journal Article] Development of individualized immunotherapy based on the analysis on anti-tumor immune responses to the human tumor antigens identified using immunological and genetic methods2007
- Author(s)
  Kawakami Y, Fujita T, Kudo C, Sakurai T, Udagawa M, Hasegawa G, Ishida A, Kitagawa Y, Tanabe M, Saito M, Izumi Y, Kawamura M, Yaguchi T, Ueda Y, Hayashi E, Wang Q, Tsukamoto N, Matsuzaki Y, Sumimoto H, Takeuchi H, Tanikawa A, Handa M, Amagai M, Kobayashi K, Ikeda Y, Azuma I, and Kitajima M.
- Journal Title
  
  Gene Therapy 2007
  
  Pages: 240-248
- Data Source
  KAKENHI-PROJECT-19591562
[Patent] 抗腫瘍免疫療法増強剤2018
- Inventor(s)
  塚本信夫、河上裕
- Industrial Property Rights Holder
  塚本信夫、河上裕
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-16K07181
[Patent] 抗腫瘍免疫療法増強剤2017
- Inventor(s)
  塚本信夫、河上裕
- Industrial Property Rights Holder
  塚本信夫、河上裕
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-127973
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K07181
[Patent] がん免疫療法2012
- Inventor(s)
  塚本信夫、松下麻衣子、服部豊、河上裕
- Industrial Property Rights Holder
  塚本信夫、松下麻衣子、服部豊、河上裕
- Industrial Property Number
  2012-132288
- Filing Date
  2012-06-11
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] Immunosuppression caused by IDO protein stability in tumor microenvironment2019
- Author(s)
  TSUKAMOTO Nobuo, KUROSAKI Sou, INOUE Jun-ichiro, KAWAKAMI Yutaka
- Organizer
  第４８回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K07758
[Presentation] がん微小環境の代謝制御による免疫チェックポイント阻害剤の治療効果増強2018
- Author(s)
  河上裕、塚本信夫、谷口智憲
- Organizer
  第２２回日本がん免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07181
[Presentation] Berberine augments tumor antigen specific T cells in vivo through metabolic remodeling in CD8+ T cells in tumors and lymph nodes.2017
- Author(s)
  Nobuo Tsukamoto, Hajime Kamijuku, Yutaka Kawakami
- Organizer
  第46回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K07181
[Presentation] Signal crosstalk of aryl hydrocarbon receptor (AhR) and IDO phosphorylation in tumor microenvironment.2016
- Author(s)
  Nobuo Tsukamoto, Kento Shimamoto, Yuto Sakai, Hajime Kamijuku and Yutaka Kawakami
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  Okinawa Convention Center（沖縄県・宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-16K07181
[Presentation] Molecular mechanisms of immunosuppression by aryl hydrocarbon receptor (AhR) in tumor microenvironment2015
- Author(s)
  Nobuo Tsukamoto, Hajime Kamijuku, Yutaka Kawakami
- Organizer
  2015 日本免疫学会総会・学術集会
- Place of Presentation
  Sapporo Convention Center（北海道・札幌市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-25430158
[Presentation] 白血病幹細胞に発現する新規がん精巣抗原の同定2015
- Author(s)
  松下麻衣子、小沢光司、中村美紀、鈴木拓真、市川大樹、塚本信夫、河上裕、服部豊
- Organizer
  第12回日本免疫治療学研究会学術集会
- Place of Presentation
  東京ガーデンパレス（東京都文京区）
- Year and Date
  2015-02-28
- Data Source
  KAKENHI-PROJECT-25430158
[Presentation] Berberine has direct enhancing activities on anti-tumor memory and effector T cells2015
- Author(s)
  Hajime Kamijuku, Nobuo Tsukamoto, Jeong Hoon Park, Hsin-ju Liu, Yutaka Kawakami
- Organizer
  International Conference of Cancer Immunotherapy and Macrophages 2015
- Place of Presentation
  東京大学伊藤国際学術センター内伊藤謝恩ホール（東京都・文京区）
- Year and Date
  2015-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430158
[Presentation] Berberine has direct enhancing activities on anti-tumor memory and effector T cells2015
- Author(s)
  Hajime Kamijuku, Nobuo Tsukamoto, Yutaka Kawakami
- Organizer
  第74回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25430158
[Presentation] In vivo anti-tumor effects of berberine through augmentation of anti-tumor T-cell responses2014
- Author(s)
  Kamijuku H, Tsukamoto N, Park JH, Liu H, Kawakami Y.
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] In vivo anti-tumor effects of berberine through augmentation of anti-tumor T-cell responses2014
- Author(s)
  Hajime Kamijuku, Nobuo Tsukamoto, Jeong Hoon Park, Hsin-ju Liu and Yutaka Kawakami
- Organizer
  第43回　日本免疫学会学術集会
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PROJECT-25430158
[Presentation] Immunosuppression by downstream molecules regulated by aryl hydrocarbon receptor (AhR) in tumor microenvironment2014
- Author(s)
  Tsukamoto N, Park JH, Kamijuku H, Kawakami Y.
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] Role of aryl hydrocarbon receptor in immunosuppression of tumor microenvironment.2013
- Author(s)
  Park JH, Tsukamoto N, Kamijuku H, Kimura A, Kawakami Y
- Organizer
  2013 日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-25430158
[Presentation] Augmentation of anti-tumor immune responses by Kampo medicine compounds with aryl hydrocarbon receptor (AhR) antagonistic activity.2013
- Author(s)
  Tsukamoto Nobuo, Park Jeong Hoon, Kamijuku Hajime, Popivanova Boryana, Kawakami Yutaka.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ、千葉県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Augmentation of anti-tumor immune responses by Kampo medicine compounds which inhibits signaling associated with cancer induced immunosuppression.2013
- Author(s)
  Kamijuku H, Tsukamoto N, Park JH, Kawakami Y
- Organizer
  2013 日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-25430158
[Presentation] Identification of novel cancer-testis antigen expressed in leukemic stem cells of chronic myelogenous leukemia.2013
- Author(s)
  Nakamura M, Matsushita M, Ichikawa D, Tsukamoto N, Kawakami Y, Hattori Y
- Organizer
  2013 日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-25430158
[Presentation] Augmentation of anti-tumor immune responses by Kampo medicine compounds with aryl hydrocarbon receptor (AhR) antagonistic activity.2013
- Author(s)
  Tsukamoto N, Park JH, Kamijuku H, Popivanova B, Kawakami Y
- Organizer
  2013 日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-25430158
[Presentation] Augmentation of anti-tumor immune responses by a Kampo medicine compound which inhibits signaling associated with cancer induced immunosuppression2013
- Author(s)
  Kamijuku Hajime, Tsukamoto Nobuo, Park Jeong Hoon Kawakami Yutaka
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ、千葉県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Identification of novel cancer-testis antigen expressed in leukemic stem cells of chronic myelogenous leukemia2013
- Author(s)
  Nakamura Miki, Matsushita Maiko, Ichikawa Daiju, Tsukamoto Nobuo, Kawakami Yutaka.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ、千葉県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Role of aryl hydrocarbon receptor in immunosuppression of tumor microenvironment.2013
- Author(s)
  Park Jeong Hoon, Tsukamoto Nobuo, Kamijuku Hajime, Kimura Akihiro, Kawakami Yutaka.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ、千葉県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Roles of aryl hydrocarbon receptor (AhR) in cancer progression in tumor microenvironment2012
- Author(s)
  Tsukamoto N, 4名, Kawakami Y.
- Organizer
  2012年日本癌学会
- Place of Presentation
  ロイトン札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] New diagnostic and therapeutic target KU-MEL9 for chronic myeloid leukemia (CML)2012
- Author(s)
  Matsushita M, 3 名, Tsukamoto N,Kawakami Y, 3 名.
- Organizer
  AACR Anual Meeting2012
- Place of Presentation
  Chicago USA
- Year and Date
  2012-04-02
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] Identification of human melanoma antigen with favorable characteristics for the use in immunotherapy2012
- Author(s)
  Tsukamoto N, 3 名, Kawakami Y.
- Organizer
  2012 年日本免疫学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2012-12-06
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] Identification of human melanoma antigen with favorable characteristics for the use in immunotherapy2012
- Author(s)
  Nobuo Tsukamoto
- Organizer
  第４１回日本免疫学会総会・学術集会
- Place of Presentation
  神戸国際会議場他（神戸市）
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] Roles of aryl hydrocarbon receptor (AhR) in cancer progression in tumor microenvironment2012
- Author(s)
  Nobuo Tsukamoto
- Organizer
  第７１回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌他（札幌市）
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] Augmentation of anti-tumor immune responses by Kampo medicine compound which inhibits signaling associated with cancer induced immunosuppression2012
- Author(s)
  Kamijuku H, 1 名, Tsukamoto N, 4 名,Kawakami Y.
- Organizer
  2012 年日本免疫学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] トリプトファン代謝産物による芳香族炭化水素受容体を介したがん免疫抑制2011
- Author(s)
  小室美紗、塚本信夫、松村友美子、河上裕
- Organizer
  第40回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉県)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] がん免疫逃避機構とその制御2011
- Author(s)
  河上裕、住本秀敏、岩田知子、川村直、谷口智憲、西尾浩、工藤千恵、塚本信夫
- Organizer
  第15回日本がん免疫学会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府)
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] がん免疫逃避機構とその制御2011
- Author(s)
  河上裕, 6名, 塚本信夫
- Organizer
  2011 年日本がん免疫学会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] Enhanced metastasis through immunosuppressive cancer microenvironment and its control by targeting signaling molecules2011
- Author(s)
  Kawakami Y, 2 名, Tsukamoto N, 4 名.
- Organizer
  2011年日本癌学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] がん免疫逃避機構とその制御2011
- Author(s)
  河上裕、塚本信夫, その他
- Organizer
  第15回日本がん免疫学会総会
- Place of Presentation
  大阪府・千里ライフサイエンスセンター、大阪
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-21591445
[Presentation] がん微小環境免疫抑制病態による転移促進とその制御2011
- Author(s)
  河上裕、工藤、住本、塚本信夫, 他4名
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)(招待講演)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] がん免疫逃避機構とその制御2011
- Author(s)
  河上裕、塚本信夫, その他
- Organizer
  第15回日本がん免疫学会
- Place of Presentation
  大阪府・千里ライフサイエンスセンター
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-21591445
[Presentation] Involvement of CCL22/CCR4 in lymph node metastasis of human head and neck cancer via increasing invasion ability2011
- Author(s)
  Tsujikawa T, 3名, Tsukamoto N, 4名,Kawakami Y.
- Organizer
  2011年日本癌学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] CCL22/CCE4は癌細胞浸潤能増加によりヒト頭頸部扁平上皮癌のリンパ節転移に関与する2011
- Author(s)
  辻川敬裕、谷口、小林、植田、塚本信夫, 他5名
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] Enhanced metastasis through immunosuppressive cancer microenvironment and its control by targeting signaling molecules2011
- Author(s)
  Kawakami Y, Tsukamoto N, その他
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋国際会議場、名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21591445
[Presentation] IDO-catabolized tryptophan metabolite may be involved in the generation of immunosuppressive tumor microenvironment through induction of Treg via AhR activation2011
- Author(s)
  Komuro M, Tsukamoto N, 1名, Kawakami Y.
- Organizer
  2011年日本免疫学会
- Place of Presentation
  幕張メッセ
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] Enhanced metastasis through immunosuppressive cancer microenvironment and its control by targeting signaling molecules2011
- Author(s)
  Kawakami Y、Tsukamoto N, その他
- Organizer
  第70回日本癌学会
- Place of Presentation
  愛知県・名古屋国際会議場
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21591445
[Presentation] トリプトファン代謝産物による芳香族炭化水素受容体を介したがん免疫抑制2011
- Author(s)
  小室美紗、塚本信夫, 他2名
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉県)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] 悪性黒色腫および樹状細胞でのWnt/β-cateninシグナル亢進はがん微小環境での免疫抑制に関与する2010
- Author(s)
  谷口智憲、桜井敏晴、塚本信夫、藤田知信、河上裕
- Organizer
  第14回日本がん免疫学会総会
- Place of Presentation
  KKRホテル熊本、熊本
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-21591445
[Presentation] がん免疫逃避機構とその制御2010
- Author(s)
  河上裕, 2名, 塚本信夫, 4名
- Organizer
  2010 年日本がん免疫学会
- Place of Presentation
  KKRホテル熊本
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] Immune escape of Snail/Slug induced EMT cancer cells through down-regulation of MICA and MICB2010
- Author(s)
  Tsukamoto N, 3名, Kawakami Y.
- Organizer
  2010年日本癌学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] Possible improvement of cancer immunotherapy based on the analyses of anti-tumor immune responses in human2010
- Author(s)
  Yutaka Kawakami, Nobuo Tsukamoto, Tomonobu Fujita, Toshiharu Sakurai, Tomonori Yaguchi
- Organizer
  金沢国際がん生物学シンポジュウム
- Place of Presentation
  KKRホテル金沢、金沢
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-21591445
[Presentation] Cancer-testis antigen BORIS is a novel prognostic marker for patients with esophageal cancer2010
- Author(s)
  Okabayashi K, 6名, Tsukamoto N, 4名,Kawakami Y.
- Organizer
  2010年日本癌学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] NKp44 ligand expression on cancer cells is down-regulated by EMT2010
- Author(s)
  Ida Y., Tsukamoto N, 6名, Kawakami Y.
- Organizer
  2010年日本癌学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] NKp44 ligand expression on cancer cells is down-regulated by EMT.2010
- Author(s)
  井田陽介、塚本信夫, 他7名
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22501025
[Presentation] ヒト悪性黒色腫癌細胞株side populadon分画の癌肝細胞様性質と免疫抵抗性2009
- Author(s)
  塚本信夫、長谷川豪、永濱康晴、大波陽子、河上裕
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  国際フォーラム
- Year and Date
  2009-03-06
- Data Source
  KAKENHI-PROJECT-17016070
[Presentation] ヒト悪性黒色腫癌細胞株sidepopulation分画の癌幹細胞様性質と免疫抵抗性2009
- Author(s)
  塚本信夫、長谷川豪、永濱康晴、大浪陽子、河上裕
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2009-03-06
- Data Source
  KAKENHI-PROJECT-19591562
[Presentation] 癌細胞におけるMAPKシグナル亢進による腫瘍免疫逃避機構の解明2008
- Author(s)
  谷口智憲、木藤健治、塚本信夫、桜井敏晴、藤田知信、持丸博史、丸山正太郎、里見良輔、井田陽介、住本秀敏、河上裕
- Organizer
  第38回日本免疫学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-17016070
[Presentation] 大腸癌新規診断マーカーとしてのKU-CR4の同定2008
- Author(s)
  塚本信夫, 寺本華菜, 岡田勉, 大浪陽子, 井田陽介, 河上裕
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19390355
[Presentation] 大腸癌新規診断マーカーとしてのKU-CR4の同定2008
- Author(s)
  塚本信夫、寺本華菜、岡田勉、大浪陽子、井田陽介、河上裕
- Organizer
  第67回日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19390355
[Presentation] Molecular mechanismis for immuno-suppression induced by melanoma cells2008
- Author(s)
  Kawakami Y, Sumimoto H, Kudo C, Tsukamoto N, Yaguchi T
- Organizer
  20th International Pigment Cell Conference & 5th International Melanoma Research Congress
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2008-05-12
- Data Source
  KAKENHI-PROJECT-17016070
[Presentation] 癌肝細胞様性質を示すヒト癌細胞株sidepopulatiOn分画の免疫抵抗性機序2008
- Author(s)
  塚本信夫、長谷川豪、永濱康晴、大波陽子、河上裕
- Organizer
  第38回日本免疫学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-17016070
[Presentation] Tomonobu Fujita, Toshiharu Sakurai, Tomonori Yaguchi, Tomoko Iwata, Naoshi Kawamura, Use of cultured dendritic cells for immunotherapy of cancer2008
- Author(s)
  Yutaka Kawakami, Hidetoshi Sumimoto, Chie Kudo, Nobuo Tsukamoto
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19591562
[Presentation] 癌細胞におけるMAPKシグナル亢進による腫瘍免疫逃避機構の解明2008
- Author(s)
  谷口智憲, 木藤健治, 塚本信夫, 桜井敏晴, 藤田知信, 持丸博史, 丸山正太郎, 里見良輔, 井田陽介, 住本秀敏, 河上裕
- Organizer
  第38回日本免疫学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19390355
[Presentation] 癌幹細胞様性質を示すヒト癌細胞株side pqpulation分画の免疫抵抗性機序2008
- Author(s)
  塚本信夫、永濱康晴、長谷川豪、大浪陽子、河上裕
- Organizer
  第12回基盤的癌免疫研究会総会
- Place of Presentation
  大宮ソニックシティ
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-17016070
[Presentation] 癌細胞におけるMAPKシグナル亢進による腫瘍免疫逃避機構の解明2008
- Author(s)
  谷口智憲、木藤健治、塚本信夫、桜井敏晴、藤田知信、持丸博史、丸山正太郎、里見良輔、井田陽介、住本秀敏、河上裕
- Organizer
  第38回日本免疫学会
- Place of Presentation
  京都
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19390355
[Presentation] Molecular mechanismis for immuno-suppression induced by melanoma cells2008
- Author(s)
  Kawakami Y, Sumimoto H, Kudo C, Tsukamoto N. Yaguchi T
- Organizer
  20th International Pigment Cell Conference & 5th International Melanoma Research Congress
- Place of Presentation
  Royton Sapporo(Japan)
- Year and Date
  2008-05-12
- Data Source
  KAKENHI-PROJECT-17016070
[Presentation] Identification of KU-CR4 as a Potential Diagnostic Marker for Colorectal Carcinomas2008
- Author(s)
  Nobuo Tsukamoto, Kana Teramoto, Tsutomu Okada, Yoko Onami, Yosuke Ida, Yuko Kitagawa, Yutaka Kawakami
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19591562
[Presentation] 培養樹状細胞を用いた免疫療法2008
- Author(s)
  河上裕, 住本秀敏, 工藤千恵, 塚本信夫, 藤田知信, 桜井敏晴, 谷口智憲, 岩田知子, 川村直
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19390355
[Presentation] Wnt/β-cateninシグナル亢進による悪性黒色腫の免疫逃避機構の解明2008
- Author(s)
  谷口智憲、木藤健治、塚本信夫、桜井敏晴、持丸博史、丸山正太郎、里見良輔、井田陽介、住本秀敏、河上裕
- Organizer
  第12回基盤的癌免疫研究会総会
- Place of Presentation
  大宮ソニックシティ
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-17016070
[Presentation] Possible mechanisms for immune-resistance of side population of human cancer cell lines with cancer stem like characteristics2008
- Author(s)
  Nobuo Tsukamoto, Go Hasegawa, Yasuharu Nagahama, Yoko Onami, Yutaka Kawakami
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19591562
[Presentation] Wnt/beta-cateninシグナル亢進による悪性黒色種の免疫逃避機構の解明2008
- Author(s)
  谷口智憲、木藤健治、塚本信夫、桜井敏晴、持丸博史、丸山正太郎、里見良輔、井田陽介、住本秀敏、河上裕
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-17016070
[Presentation] MMAIによる細胞増殖とインテグリンを介した細胞接着増強によるヒト悪性黒色腫転移機構2008
- Author(s)
  藤田知信、松崎ゆり子、宮崎潤一郎、岩田卓、塚本信夫、河上裕
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-17016070
[Presentation] Identification of KU-CR4 as a Potential Diagnostic Marker for Colorectal Carcinomas.2008
- Author(s)
  Nobuo Tsukamoto
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19591562
[Presentation] 培養樹状細胞を用いた免疫療法2008
- Author(s)
  河上裕、住本秀敏、工藤千恵、塚本信夫、藤田知信、桜井敏晴、谷口智憲、岩田知子、川村直
- Organizer
  第67回日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19390355
[Presentation] Possible immunosuppression by pDC impairment through expression of immunoglobulin-like transcript 7 ligand (ILT7L) on lung cancer cells2008
- Author(s)
  Nobuo Tsukamoto, and Yutaka Kawakami
- Organizer
  The 13^<th> Japan-Korea Cancer Research Workshop
- Place of Presentation
  韓国
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-19591562
[Presentation] 培養樹状細胞を用いた免疫療法2008
- Author(s)
  河上裕、住本秀敏、工藤千恵、塚本信夫、藤田知信、桜井敏晴、谷口智憲、岩田知子、川村直
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-17016070
[Presentation] 癌細胞におけるimmunoglobulin-like transcript 7 (ILT7) リガンドの発現と免疫抑制2007
- Author(s)
  Tsukamoto N, Okada S, Sasaki Y, Kawakami Y
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19390355
[Presentation] Possible immunosuppression by ligands for immunoglobulin-like transcript 7 (ILT7) expressed on cancer cells2007
- Author(s)
  Nobuo Tsukamoto, Starlyn Okada, Yusuke Sasaki, Yutaka Kawakami
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  グランドプリンスホテル新高輪
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19591562
[Presentation] Immunoglobulin-like transcript 7(ILT7)リガンドの癌細胞株における発現2007
- Author(s)
  塚本信夫、Okada S、佐々木雄亮、河上裕
- Organizer
  第11回基盤的癌免疫研究会
- Place of Presentation
  東京
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-19390355
[Presentation] Immunosuppressive mechanisms induced by tumor cells during epithelial-mesenchymal transition2007
- Author(s)
  Kudo C, Shirako H, Oike M, Tsukamoto N, Kawakami Y
- Organizer
  第66回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19390355
[Presentation] Immunoglobiilin-like transcript 7(ILT7)リガンドの癌細胞株における発現2007
- Author(s)
  塚本信夫その他
- Organizer
  第11回基盤的癌免疫研究会
- Place of Presentation
  東京大学・鉄門講堂
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-17016070
[Presentation] Immunoglobulin-like transcript 7 (ILT7)リガンドの癌細胞株における発現2007
- Author(s)
  塚本信夫, その他
- Organizer
  第11回基盤的癌免疫研究会
- Place of Presentation
  東京大学・鉄門講堂
- Year and Date
  2007-01-11
- Data Source
  KAKENHI-PROJECT-19390355
[Presentation] BORIS is a possible marker for poor prognosis with distant metastasis in patients with colorectal cancer2007
- Author(s)
  Fujita T, Hirao N, Okada T, Tsukamoto N, Okabayashi K, Kitagawa Y, Kitajima M, Kawakami Y
- Organizer
  第66回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19390355
[Presentation] Immunosuppressive mechanisms induced by tumor cells duringepitherial-mesenchymal transitions2007
- Author(s)
  Chie Kudo, Nobuo Tsukamoto, Yutaka Kawakami, et. al.
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜・パセフィコ横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-18591484
[Presentation] Possible immunosuppression by ligands for immunoglobiilm-like transcript7(ILT7)・2007
- Author(s)
  Tsukamoto N, et. al.
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  グランドプリンスホテル新高輪
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-17016070
[Presentation] Possible immunosuppression by ligands for immunoglobulin-like transcript 7(ILT7)2007
- Author(s)
  Tsukamoto N, et. al.
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  グランドプリンスホテル新高輪
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19390355
[Presentation] Development of invidualized immunotherapy by intratumoral injection of dendritc cells based on the immunological analysis of the malanoma antigens identified by various methods2005
- Author(s)
  Kawakami Y, Fujita T, Matsuzaki Y, Sakurai T, Tsukamoto M, Sumimoto H, Hasegawa G, Udagawa M
- Organizer
  19th International Pigment cell Conference
- Place of Presentation
  Reston VA, USA
- Year and Date
  2005-09-21
- Data Source
  KAKENHI-PROJECT-17016070
[Presentation] ん微小環境における芳香族炭化水素受容体のがん悪性化への役割
- Author(s)
  塚本信夫
- Organizer
  第71回日本癌学会
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Immunosuppression by downstream molecules regulated by aryl hydrocarbon receptor (AhR) in tumor microenvironment
- Author(s)
  Nobuo Tsukamoto, Jeong Hoon Park, Hajime Kamijuku and Yutaka Kawakami
- Organizer
  第43回　日本免疫学会学術集会
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25430158
[Presentation] IDENTIFICATION OF NOVEL CANCER-TESTIS ANTIGEN EXPRESSED IN LEUKEMIC STEM CELLS OF CHRONIC MYELOGENOUS LEUKEMIA
- Author(s)
  Maiko Matsushita, Miki Nakamura, Daiju Ichikawa, Nobuo Tsukamoto, Yutaka Kawakami, Yutaka Hattori
- Organizer
  ISEH 43rd Annual Scientific Meeting
- Place of Presentation
  モントリオール（カナダ）
- Year and Date
  2014-08-21 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-25430158

1. KAWAKAMI Yutaka (50161287)

# of Collaborated Projects: 12 results

# of Collaborated Products: 94 results
2. SAKURAI Toshiharu (20101933)

# of Collaborated Projects: 5 results

# of Collaborated Products: 15 results
3. FUJITA Tomonobu (20199334)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
4. KUDO Chie (90424126)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
5. SUMIMOTO Hidetoshi (00306838)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
6. OHTA Shigeki (20365406)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. YAGUCHI Tomonori (40424163)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
8. UEDA Ryo (30317143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. MATSUZAKI Yuriko (40255435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TSUKAMOTO Makoto (50365441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
11. KITAGAWA Yuukou (20204878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. KAWAMURA Naoshi (30570246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 長谷川豪 (80383751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 竹内裕也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 鈴木ゆり子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Tsukamoto Nobuo 塚本 信夫

TSUKAMOTO Nobuo 塚本 信夫

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of antitumor immunity enhancing effects of berberine and development of effective combination immunotherapyPrincipal Investigator

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Analysis of non-uniform immune-suppressive mechanisms in tumor microenvironment and development of effective anti-tumor immune therapiesPrincipal Investigator

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Study on roles of aryl hydrocarbon receptor (AhR) in tumor microenvironment and estimation of AhR as a therapeutic target for cancer patientsPrincipal Investigator

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Systematic analysis of cellular signaling involved in the melanoma induced immunosuppression

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Development of effective immunotherapy by combining interventions on key points in the anti-tumor immune network

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Analysis of mechanisms for immunosuppression through ILT7/NKp44/BDCA2 ligands expressed on cancer cellsPrincipal Investigator

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Elucidation of the resistance mechanisms of immunotherapy by the abnormal signal transduction in melanoma and development of methods to overcome it

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iPS細胞・間葉系幹細胞からの色素細胞と悪性黒色腫の作成と発現分子の臨床応用

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Development of effective immunotherapy by combining methods to restore immunocompetence of cancer patients

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Development of diagnostic method and immunotherapy using a novel molecule specifically expressed in colorectal carcinomasPrincipal Investigator

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The study of immunosuppressive mechanisms induced by gastrointestinal cancer during epithelial-mesnchymal transition and clinical application of this target therapy

Principal Investigator

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Development of immunotherapy based on the identification of tumor antigens

Principal Investigator

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Review Section

Research Institution

[Book] Cancer Induced Immunosuppression and its Modulation by Signal Inhibitors in “Resistance of cancer cells to CTL-mediated immunotherapy” Eds: Chouaib S and Bonavida B,2015

Author(s)

Publisher

Tsukamoto Nobuo 塚本信夫

TSUKAMOTO Nobuo 塚本信夫

[Book] Development of personalized combination cancer immunotherapy based on the patients’ immune status in “Inflammation and immunity in cancer ”　Eds:Tsukasa Seya, Keiko Udaka, Misako Matsumoto, Noriyuki Sato2015