Yaguchi Tomonori 谷口智憲

… Alternative Names

YAGUCHI Tomonori 谷口智憲

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Researcher Number	40424163
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 特定准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 京都大学, 医学研究科, 特定講師 2016 – 2021: 慶應義塾大学, 医学部(信濃町), 講師 2017: 慶應義塾大学, 医学部, 講師 2009 – 2015: Keio University, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Dermatology / Medium-sized Section 50:Oncology and related fields / Basic Section 53050:Dermatology-related / Tumor therapeutics / Experimental pathology Except Principal Investigator Dermatology / Medium-sized Section 53:Organ-based internal medicine and related fields / Obstetrics and gynecology / Medium-sized Section 42:Veterinary medical science, animal science, and related fields … More / Basic Section 42020:Veterinary medical science-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 56040:Obstetrics and gynecology-related / Tumor immunology Less
Keywords	Principal Investigator がん免疫療法 / 腫瘍免疫 / 悪性黒色腫 / 免疫記憶 / がん免疫治療 / ERストレス / メラノーマ / β-カテニン / beta-catenin / 免疫療法 … More / 免疫抑制 / EGFR-TKI / 肺癌 / 線維芽細胞 / 樹状細胞 / 腫瘍間質 / 癌免疫療法 / 腫瘍免疫回避 / 間葉系幹細胞 … More Except Principal Investigator がん免疫療法 / 免疫療法 / 悪性黒色腫 / 免疫抑制 / CAR-T細胞 / 免疫逃避 / 腫瘍免疫学 / 腫瘍 / 犬 / Comparative Oncology / CAR-T細胞療法 / 腫瘍免疫 / 免疫寛容 / 免疫制御 / 卵巣がん / 子宮頸癌 / T細胞 / 腫瘍抗原 / コレステロール25水酸化酵素 / 炎症収束機構 / ポドプラニン / 腫瘍免疫療法 / PDPN / 固形腫瘍 / 獣医腫瘍免疫学 / 細胞療法 / 比較腫瘍学 / HER2 / GPC1 / 心筋細胞 / 腫瘍化 / 再生医療 / ヒト多能性幹細胞 / 奇形腫形成抑制 / 奇形種形成抑制 / 心筋細胞移植 / iPS細胞 / 未分化細胞除去法 / CART細胞療法 / 治療 / T細胞疲弊 / 腫瘍浸潤リンパ球 / 養子免疫療法 / 腫瘍浸潤リンパ球輸注療法 / 免疫制御機構 / コレステロール代謝 / デスモグレイン3 / 免疫寛容機構 / 自己免疫疾患 / 天疱瘡 / 免疫チェックポイント / immunoescape / ovarian cancer / regulatory Tcell / immunotherapy / 制御性T細胞 / がん微小環境 / 卵巣癌 / 分子標的治療 / 分子標的薬 / 分子標的治療薬 / 網羅的分子解析 / サイトカイン / STAT3 / NF-ｋB / HNF-1beta / HOXD9 / 細胞分子機構 / 免疫病態 / TGF-β / TGF-b1 / 免疫抑制機構 / センチネルリンパ節 / 診断 / バイオマーカー / miRNA / 生体内腫瘍破壊法 / エフェクター細胞 / 免疫抑制制御 / 免疫チェックポイント阻害 / 樹状細胞 Less

Comparative analysis of immunological memory against cancersPrincipal Investigator
- Principal Investigator
  
  谷口智憲
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyoto University
犬固形腫瘍に対する併用CAR-T細胞療法の開発
- Principal Investigator
  
  加藤大貴
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  The University of Tokyo
コレステロール代謝を利用した皮膚の新規炎症収束機構の解明
- Principal Investigator
  
  高橋勇人
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Keio University
抗腫瘍免疫応答に関与する遺伝子スプライシング機構の解明Principal Investigator
- Principal Investigator
  
  谷口智憲
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kyoto University
Analysis of immunosuppression by ER stress in cancer microenvironmentsPrincipal Investigator
- Principal Investigator
  
  Yaguchi Tomonori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyoto University
Development of fail-safe system for human iPSC-derived tumor by CAR-T cell therapyCAR-T cell therapy
- Principal Investigator
  
  Fukuda Keiichi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Keio University
Development of a low-cost, ready-made, adaptable CAR-T cell product for canine solid tumors
- Principal Investigator
  
  Kato Daiki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
Functional analysis of novel immune checkpoints and development of combined immunotherapy in gynecological cancer
- Principal Investigator
  
  Nishio Hiroshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Keio University
Analysis on a new immunoregulatory mechanism to control pathogenic T cell repertoires
- Principal Investigator
  
  TAKAHASHI Hayato
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Keio University
Development of TIL culture method for tumor infiltrating T cell therapy for cervical cancer
- Principal Investigator
  
  IWATA Takashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Keio University
Evaluation of the role of beta-catenin pathway in human melanoma in anti-cancer immune responsesPrincipal Investigator
- Principal Investigator
  
  Yaguchi Tomonori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Kyoto University
  Keio University
Identification of the sub-population in human malignant melanoma showing strong resistance to tumor specific cytotoxic T cellsPrincipal Investigator
- Principal Investigator
  
  Yaguchi Tomonori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Development of a novel molecular targeted therapy against acral melanomas
- Principal Investigator
  
  NAMIKI Takeshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Tokyo Medical and Dental University
Investigating cancer-immunoescape mechanism and effective immuunotherapy for ovarian cancer
- Principal Investigator
  
  Hiroshi Nishio
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
Systematic analysis of cellular signaling involved in the melanoma induced immunosuppression
- Principal Investigator
  
  KAWAKAMI Yutaka
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Enhancement of anti-tumor immune responses by EGFR-TKIs (EGFR- tyrosin kinase inhibitors)Principal Investigator
- Principal Investigator
  
  YAGUCHI Tomonori
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Keio University
Elucidation of the condition of construction mechanisms of immunity on sentinel lymph nodes of patients with melanoma and development of novel immunotherapy
- Principal Investigator
  
  SAKURAI TOSHIHARU
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Expression and Functional Analysis of HOXD9 in Cervical Cancer
- Principal Investigator
  
  KATSUMI Tsukazaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
Development of effective immunotherapy by combining interventions on key points in the anti-tumor immune network
- Principal Investigator
  
  KAWAKAMI Yutaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Tumor immunology
- Research Institution
  Keio University
Investigation of roles of miRNA in the immunosuppression and clinical use for patients with melanoma
- Principal Investigator
  
  KAWAKAMI Yutaka
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Keio University
The role of Histatin-1 ectopically expressed in human melanoma cellsPrincipal Investigator
- Principal Investigator
  
  YAGUCHI Tomonori
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Elucidation of the mechanism of immunosuppression by mesenchymal stem cells in cancer microenvironmentsPrincipal Investigator
- Principal Investigator
  
  YAGUCHI Tomonori
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Experimental pathology
- Research Institution
  Keio University

[Book] Cancer Induced Immunosuppression and its Modulation by Signal Inhibitors in “Resistance of cancer cells to CTL-mediated immunotherapy” Eds: Chouaib S and Bonavida B,2015
- Author(s)
  Kawakami Y, Qian L, Kawamura N, Miyazaki J, Tsubota K, Kinoshita T, Nakaura K, Ohmura G, Satomi R, Sugiyama J, Nishio H, Hayakawa T, Popivanova B, Nuchsupha S, Liu TH, Kamijuku H, Kudo-Saito C, Tsukamoto N, Sakurai T, Fujita T, Yaguchi T.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25670506
[Book] Development of personalized combination cancer immunotherapy based on the patients’ immune status in “Inflamamtion and immunity in cancer ” Eds:Tsukasa Seya, Keiko Udaka, Misako Matsumoto, Noriyuki Sato,2015
- Author(s)
  Kawakami Y, Qian L, Kawamura N, Miyazaki J, Nagumo H, Tsubota K, Kinoshita , Nakamura K, Ohmura G, Satomi R, Sugiyama J, Nishio H, Hayakawa T, Popivanova B, Nuchsupha S, Liu TH, Kamijuku H, Kudo-Saito C, Tsukamoto N, Sakurai T, Fujita T, Yaguchi T.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25670506
[Book] Intratumoral Injection of BCG-CWS-Pretreated Dendritic Cells Following Tumor Cryoablation.in “Cancer Vaccines Methods and Protocols” Eds, Michael J.P., Patricia D.2014
- Author(s)
  1.Kawamura N, Udagawa M, Fujita T, Sakurai T, Yaguchi T, Kawakami Y
- Publisher
  Human Press
- Data Source
  KAKENHI-PROJECT-25670506
[Book] The Tumor Immunoenvironment2013
- Author(s)
  Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Kamijuku H, Tsujikawa T,KawamuraN
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23659554
[Book] Roles of signaling pathways in cancer cells and immune cells in generation of immunosuppressive tumor associated microenvironments. in “The Tumor Immunoenvironment” Eds, Michael Shurin, Anatoli Malyguine, Viktor Umansky,2013
- Author(s)
  1. Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Kamijuku H, Tsujikawa T, Kawamura N.
- Publisher
  Springer Science.
- Data Source
  KAKENHI-PROJECT-25670506
[Book] Roles of signaling pathways in cancer cells and immune cells in generation of immunosuppressive tumor associated microenvironments. in "The Tumor Immunoenvironment" Eds, Shurin M, Malyguine A, Umansky V2013
- Author(s)
  Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Kamijuku H, Tsujikawa T, Kawamura N
- Publisher
  Springer Science
- Data Source
  KAKENHI-PROJECT-23240128
[Book] Roles of signaling pathways in cancer cells and immune cells in generation of immunosuppressive tumor associated microenvironments. in “The Tumor Immunoenvironment” Eds, Michael Shurin, Anatoli Malyguine, Viktor Umansky,2013
- Author(s)
  Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Kamijuku H, Tsujikawa T,Kawamura N
- Publisher
  Springer Science
- Data Source
  KAKENHI-PROJECT-23240128
[Book] Human tumor antigens recognized by T cells and their implications for cancer immunotherapy in "Innate immune regulation and Cancer immunotherapy", Wang RF ed2011
- Author(s)
  Ueda R, Yaguchi T, Kawakami Y
- Publisher
  Springer Science. Business Media, New York USA
- Data Source
  KAKENHI-PROJECT-23240128
[Book] Cancer-induced immunosuppressive cascades and their reversal by molecular-targeted therapy. Annals of the New York Academy of Sciences
- Author(s)
  Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Hoon Park J, Kamijuku H, Tsujikawa T, and Kawamura N
- Publisher
  WILEY
- Data Source
  KAKENHI-PROJECT-23659554
[Journal Article] Programmed cell death-1 blockade therapy in melanoma: Resistance mechanisms and combination strategies.2023
- Author(s)
  Zou Y, Yaguchi T
- Journal Title
  
  Experimental Dermatology
  
  Volume: 32 Issue: 3 Pages: 264-275
- DOI
  10.1111/exd.14750
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02785
[Journal Article] Insights from a 30-year journey: function, regulation and therapeutic modulation of PD12023
- Author(s)
  Chamoto Kenji, Yaguchi Tomonori, Tajima Masaki, Honjo Tasuku
- Journal Title
  
  Nature Reviews Immunology
  
  Volume: - Issue: 10 Pages: 682-695
- DOI
  10.1038/s41577-023-00867-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16881, KAKENHI-PROJECT-21H02785
[Journal Article] Inhibition of stearoyl-CoA desaturase 1 (SCD1) enhances the antitumor T cell response through regulating β-catenin signaling in cancer cells and ER stress in T cells and synergizes with anti-PD-1 antibody2022
- Author(s)
  Yuki Katoh, Tomonori Yaguchi, Akiko Kubo, Takashi Iwata, Kenji Morii, Daiki Kato, Shigeki Ohta, Ryosuke Satomi, Yasuhiro Yamamoto, Yoshitaka Oyamada, Kota Ouchi, Shin Takahashi, Chikashi Ishioka, Ryo Matoba, Makoto Suematsu, Yutaka Kawakami
- Journal Title
  
  J Immunotherapy Cancer
  
  Volume: 10(7) Issue: 7 Pages: e004616-e004616
- DOI
  10.1136/jitc-2022-004616
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07199, KAKENHI-PROJECT-21K15602, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H03534, KAKENHI-PROJECT-21H02785
[Journal Article] Adoptive cell therapy using tumor-infiltrating lymphocytes for melanoma refractory to immune-checkpoint inhibitors.2021
- Author(s)
  Hirai I, Funakoshi T, Kamijuku H, Fukuda K, Mori M, Sakurai M, Koda Y, Kato J, Mori T, Watanabe N, Noji S, Yaguchi T, Iwata T, Ohta S, Fujita T, Tanosaki R, Handa M, Okamoto S, Amagai M, Kawakami Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 112 Issue: 8 Pages: 3163-3172
- DOI
  10.1111/cas.15009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21608, KAKENHI-PROJECT-21K07199, KAKENHI-PROJECT-21K08356, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H03534
[Journal Article] Inhibition of vascular adhesion protein-1 enhances the anti-tumor effects of immune checkpoint inhibitors2021
- Author(s)
  Kinoshita T, Sayem MA, Yaguchi T, Kharma B, Morii K, Kato D, Ohta S, Mashima Y, Asamura H, Kawakami Y
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 4 Pages: 1390-1401
- DOI
  10.1111/cas.14812
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03534, KAKENHI-PROJECT-19K16808, KAKENHI-PROJECT-20K21608, KAKENHI-PROJECT-21K07199, KAKENHI-PROJECT-16H06276
[Journal Article] Immune-resistant mechanisms in cancer immunotherapy2020
- Author(s)
  Kawakami Y, Ohta S, Sayem MA, Tsukamoto N, Yaguchi T.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 25 Issue: 5 Pages: 810-817
- DOI
  10.1007/s10147-019-01611-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08309, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H03534, KAKENHI-PROJECT-19K07758
[Journal Article] Tumor-infiltrating lymphocytes predict survival outcomes in patients with cervical cancer treated with concurrent chemoradiotherapy2020
- Author(s)
  Akiko Ohno, Takashi Iwata, Yuki Katoh, Shiho Taniguchi, Kohsei Tanaka, Hiroshi Nishio, Masaru Nakamura , Tohru Morisada, Guanliang Chen, Miyuki Saito, Tomonori Yaguchi, Yutaka Kawakami, Daisuke Aoki
- Journal Title
  
  Gynecol Oncol .
  
  Volume: 159 Issue: 2 Pages: 329-334
- DOI
  10.1016/j.ygyno.2020.07.106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09832, KAKENHI-PROJECT-20H03534, KAKENHI-PROJECT-18K16813
[Journal Article] GPC1 specific CAR-T cells eradicate established solid tumor without adverse effects and synergize with anti-PD-1 Ab.2020
- Author(s)
  Kato D, Yaguchi T, Iwata T, Katoh Y, Morii K, Tsubota K, Takise Y, Tamiya M, Kamada H, Akiba H, Tsumoto K, Serada S, Naka T, Nishimura R, Nakagawa T, Kawakami Y.
- Journal Title
  
  Elife.
  
  Volume: 9
- DOI
  10.7554/elife.49392
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16813, KAKENHI-PROJECT-20H03141, KAKENHI-PROJECT-19K23705
[Journal Article] S-1 in combination with docetaxel as salvage therapy for patients with metastatic extramammary Paget's disease.2020
- Author(s)
  Fukuda K, Hirai I, Nakamura Y, Fusumae T, Tanese K, Yaguchi T, Kawakami Y, Funakoshi T
- Journal Title
  
  Eur J Dermatol.
  
  Volume: 30 Issue: 3 Pages: 301-302
- DOI
  10.1684/ejd.2020.3782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08309
[Journal Article] Analysis of the tumor reactivity of tumor-infiltrating lymphocytes in a metastatic melanoma lesion that lost MHC class I expression after anti-PD-1 therapy.2019
- Author(s)
  Inozume T, Yaguchi T, Ariyasu R, Togashi Y, Ohnuma T, Honobe A, Nishikawa H, Kawakami Y, Kawamura T.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: 印刷中 Issue: 7 Pages: 30023-5
- DOI
  10.1016/j.jid.2019.01.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08309, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-16K10148, KAKENHI-PROJECT-17K16335, KAKENHI-PROJECT-17K18388, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-19K08744, KAKENHI-PROJECT-19K17794
[Journal Article] 複合免疫療法：分子標的治療薬と免疫チェックポイント阻害薬.2019
- Author(s)
  谷口智憲、河上裕
- Journal Title
  
  がん免疫療法
  
  Volume: 3 Pages: 39-41
- Data Source
  KAKENHI-PROJECT-18K08309
[Journal Article] Killer T細胞耐性とImmune editing2019
- Author(s)
  谷口智憲、河上裕
- Journal Title
  
  腫瘍内科
  
  Volume: 24 Pages: 176-182
- NAID
  40021997604
- Data Source
  KAKENHI-PROJECT-18K08309
[Journal Article] 免疫抑制分子・細胞に対する阻害薬2019
- Author(s)
  谷口智憲、河上裕
- Journal Title
  
  実験医学
  
  Volume: 37 Pages: 152-156
- Data Source
  KAKENHI-PROJECT-18K08309
[Journal Article] Transcription factor homeobox D9 is involved in the malignant phenotype of cervical cancer through direct binding to the human papillomavirus oncogene promoter2019
- Author(s)
  Hirao N, Iwata T, Tanaka K, Nishio H, Nakamura M, Morisada T, Morii K, Maruyama N, Katoh Y, Yaguchi T, Ohta S, Kukimoto I, Aoki D, Kawakami Y.
- Journal Title
  
  Gynecol Oncol
  
  Volume: 155 Issue: 2 Pages: 340-348
- DOI
  10.1016/j.ygyno.2019.08.026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11309, KAKENHI-PROJECT-19K09832, KAKENHI-PROJECT-18K16813, KAKENHI-PROJECT-16H06276
[Journal Article] 免疫チェックポイント阻害を中心とした複合がん免疫療法2017
- Author(s)
  谷口智憲、河上裕
- Journal Title
  
  Current Therapy
  
  Volume: 35 Pages: 68-73
- Data Source
  KAKENHI-PROJECT-15K09783
[Journal Article] 免疫チェックポイント阻害を中心とした複合がん免疫療法2017
- Author(s)
  谷口智憲、河上裕
- Journal Title
  
  Current therapy
  
  Volume: 35 Pages: 166-171
- Data Source
  KAKENHI-PROJECT-15K09783
[Journal Article] 癌免疫応答の制御方法/　免疫制御剤②化学療法剤以外の薬剤2017
- Author(s)
  谷口智憲、河上裕
- Journal Title
  
  実験医学
  
  Volume: 34 Pages: 1967-1975
- Data Source
  KAKENHI-PROJECT-15K09783
[Journal Article] Human PBMC-transferred murine MHC class I/II-deficient NOG mice enable long-term evaluation of human immune responses2017
- Author(s)
  Yaguchi Tomonori、Kobayashi Asuka、Inozume Takashi、Morii Kenji、Nagumo Haruna、Nishio Hiroshi、Iwata Takashi、Ka Yuyo、Katano Ikumi、Ito Ryoji、Ito Mamoru、Kawakami Yutaka
- Journal Title
  
  Cell Mol Immunol.
  
  Volume: 印刷中 Issue: 11 Pages: 1-10
- DOI
  10.1038/cmi.2017.106
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07103, KAKENHI-PROJECT-16K10148, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-17H03571, KAKENHI-PROJECT-15K09783
[Journal Article] がん免疫治療をベースとした併用治療2017
- Author(s)
  谷口智憲、河上裕
- Journal Title
  
  Vita
  
  Volume: 35 Pages: 71-77
- Data Source
  KAKENHI-PROJECT-15K09783
[Journal Article] Melanoma cells control anti-melanoma CTL responses via interaction between TIGIT and CD155 in the effector phase.2016
- Author(s)
  Inozume T, Yaguchi T, Furuta F, Harada K, Kawakami Y, Shimada S.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: 136 Issue: 1 Pages: 255-263
- DOI
  10.1038/jid.2015.404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09783, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-25461687, KAKENHI-PROJECT-26670522
[Journal Article] Cancer-induced heterogeneous immunosuppressive tumor microenvironments and their personalized modulation.2016
- Author(s)
  Yaguchi T, Kawakami Y.
- Journal Title
  
  Int. Immunol.
  
  Volume: 28 Issue: 8 Pages: 393-399
- DOI
  10.1093/intimm/dxw030
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-15K09783
[Journal Article] 免疫制御剤② シグナル阻害剤、IDO阻害剤、COX2阻害剤、CSF-1受容体阻害剤など2016
- Author(s)
  谷口智憲、河上裕
- Journal Title
  
  実験医学
  
  Volume: 34 Pages: 1967-1975
- Data Source
  KAKENHI-PROJECT-15K09783
[Journal Article] 複合がん免疫療法2016
- Author(s)
  谷口智憲、河上裕
- Journal Title
  
  Pharma Medica
  
  Volume: 34 Pages: 59-63
- Data Source
  KAKENHI-PROJECT-15K09783
[Journal Article] Prognostic value of tumor-infiltrating lymphocytes differs depending on histological type and smoking habit in completely resected non-small-cell lung cancer.2016
- Author(s)
  Kinoshita T, Muramatsu R, Fujita T, Nagumo H, Sakurai T, Noji S, Takahata E, Yaguchi T, Tsukamoto N, Kudo-Saito C, Hayashi Y, Kamiyama I, Ohtsuka T, Asamura H, Kawakami Y.
- Journal Title
  
  Ann Oncol.
  
  Volume: 27 Issue: 11 Pages: 2117-2123
- DOI
  10.1093/annonc/mdw319
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-26430122, KAKENHI-PROJECT-15K09783, KAKENHI-PROJECT-15K10731
[Journal Article] NUAK2 amplification coupled with PTEN deficiency promote melanoma development via CDK activation.2015
- Author(s)
  Namiki T, Yaguchi T, Nakamura K, Valencia JC, Coelho SG, Yin L, Kawaguchi M, Vieira WD, Kaneko Y, Tanemura A, Katayama I, Yokozeki H, Kawakami Y, Hearing VJ.
- Journal Title
  
  Cancer Res.
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670506
[Journal Article] Intratumoral Injection of BCG-CWS-Pretreated Dendritic Cells Following Tumor　Cryoablation2014
- Author(s)
  Kawamura N, Udagawa M, Fujita T, Sakurai T, Yaguchi T, Kawakami Y.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1139 Pages: 145-53
- DOI
  10.1007/978-1-4939-0345-0_13
- ISBN
  9781493903443, 9781493903450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592532, KAKENHI-PROJECT-25830122
[Journal Article] TGF-β1 in tumor microenvironments induces immunosuppression in the tumors and sentinel lymph nodes and promotes tumor progression2014
- Author(s)
  Nakamura S, Yaguchi T, Kawamura N, Kobayashi A, Sakurai T, Higuchi H, Takaishi H, Hibi T, Kawakami Y
- Journal Title
  
  J Immunother
  
  Volume: 37(2) Issue: 2 Pages: 63-72
- DOI
  10.1097/cji.0000000000000011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23240128, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24591635, KAKENHI-PROJECT-25830122
[Journal Article] がん免疫における免疫チェックポイント機構の意義とその制御によるがん治療2014
- Author(s)
  河上裕　川村直　ポピバノバ・ボリヤナ　中村謙太　早川妙香　谷口智憲
- Journal Title
  
  がん分子標的治療
  
  Volume: 12 Pages: 15-22
- Data Source
  KAKENHI-PROJECT-25830122
[Journal Article] Immunosuppression through constitutively activated NF-κB signalling in human ovarian cancer and its reversal by an NF-κB inhibitor.2014
- Author(s)
  Nishio H, Yaguchi T, Sugiyama J, Sumimoto H, Umezawa K, Iwata T, Susumu N,Fujii T, Kawamura N, Kobayashi A, Park J, Aoki D, Kawakami Y.
- Journal Title
  
  Br J Cancer.
  
  Volume: 110 Issue: 12 Pages: 2965-74
- DOI
  10.1038/bjc.2014.251
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25830122, KAKENHI-PROJECT-26221005
[Journal Article] 抗腫瘍免疫応答の総合的な制御2014
- Author(s)
  谷口智憲，河上裕.
- Journal Title
  
  血液フロンティア
  
  Volume: 24 Pages: 1579-1605
- Data Source
  KAKENHI-PROJECT-25830122
[Journal Article] がんの免疫逃避機構と分子標的薬を用いた免疫応答の制御2014
- Author(s)
  谷口智憲, 河上裕
- Journal Title
  
  産科と婦人科
  
  Volume: 81 Pages: 157-163
- Data Source
  KAKENHI-PROJECT-25830122
[Journal Article] Improvement of cancer immunotherapy by combining molecular targeted therapy2013
- Author(s)
  Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Iwata-Kajihara T, Nakamura S, Miyzaki J, Kawamura N, Hoon Park J, Popivanova B, Tsujikawa T
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 36 Pages: 1-7
- DOI
  10.3389/fonc.2013.00136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240128, KAKENHI-PROJECT-24501358, KAKENHI-PROJECT-25670506, KAKENHI-PROJECT-25830122
[Journal Article] 化学療法・分子標的薬による免疫応答増強2013
- Author(s)
  谷口智憲、河上裕
- Journal Title
  
  医学のあゆみ
  
  Volume: 244 Pages: 817-823
- Data Source
  KAKENHI-PROJECT-25830122
[Journal Article] 化学療法・分子標的薬による抗腫瘍免疫応答の制御2013
- Author(s)
  谷口智憲, 里見良輔、西尾浩、杉山重里、大村学、中村謙太、川村直、小林明日香、河上裕
- Journal Title
  
  実験医学
  
  Volume: 31 Pages: 1938-1944
- Data Source
  KAKENHI-PROJECT-25830122
[Journal Article] Angiotensin II type 1 receptor antagonist attenuates lacrimal gland, lung, and liver fibrosis in a murine model of chronic graft-versus-host disease.2013
- Author(s)
  Yaguchi S, Ogawa Y, Shimmura S, Kawakita T, Hatou S, Satofuka S, Nakamura S, Imada T, Miyashita H, Yoshida S, Yaguchi T, Ozawa Y, Mori T, Okamoto S, Kawakami Y, Ishida S, Tsubota K.
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 6 Pages: e64724-e64724
- DOI
  10.1371/journal.pone.0064724
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592590, KAKENHI-PROJECT-24592647, KAKENHI-PROJECT-25830122
[Journal Article] Autocrine and paracrine loops between cancer cells and macrophages promote lymph node metastasis via CCR4/CCL22 in head and neck squamous cell carcinoma2013
- Author(s)
  Tsujikawa T, Yaguchi T, Ohmura G, Ohta S, Kobayashi A, Kawamura N, Fujita T, Nakano H, Shimada T, Takahashi T, Nakao R, Yanagisawa A, Hisa Y, Kawakami Y
- Journal Title
  
  Int J Cancer
  
  Volume: 132(12) Issue: 12 Pages: 2755-2766
- DOI
  10.1002/ijc.27966
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240128, KAKENHI-PROJECT-23791293, KAKENHI-PROJECT-24592532
[Journal Article] 抗PD-1抗体、抗PD-L1抗体による免疫療法2013
- Author(s)
  谷口智憲, 里見良輔, 川村直, 河上裕
- Journal Title
  
  日本臨床
  
  Volume: 71 suppl 6 Pages: 253-257
- Data Source
  KAKENHI-PROJECT-25830122
[Journal Article] 化学療法・分子標的薬による免疫応答増強2013
- Author(s)
  谷口智憲、河上裕
- Journal Title
  
  医学のあゆみ
  
  Volume: 244 Pages: 817-823
- URL
  http://www.ishiyaku.co.jp/magazines/ayumi/AyumiArticleDetail.aspx?BC=924409&AC=12297
- Data Source
  KAKENHI-PROJECT-23791293
[Journal Article] 悪性黒色腫におけるPI3K/AKT経路の役割2013
- Author(s)
  谷口智憲, 川村直, 中村謙太, 河上裕
- Journal Title
  
  日本臨床
  
  Volume: 71 suppl 4 Pages: 139-143
- Data Source
  KAKENHI-PROJECT-25830122
[Journal Article] 化学療法・分子標的による抗腫瘍免疫応答の制御2013
- Author(s)
  谷口智憲、里見良輔、西尾浩、杉山重里、大村学、川村直、小林明日香、河上裕
- Journal Title
  
  実験医学
  
  Volume: 31 Pages: 1938-1944
- Data Source
  KAKENHI-PROJECT-25462614
[Journal Article] Cancer-induced immunosuppressive cascades and their reversal by molecular-targeted therapy.2013
- Author(s)
  Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Hoon Park J, Kamijuku H, Tsujikawa T, Kawamura N
- Journal Title
  
  Ann. N.Y. Acad. Sci.,
  
  Volume: 1284(1) Issue: 1 Pages: 80-86
- DOI
  10.1111/nyas.12094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240128, KAKENHI-PROJECT-25430158, KAKENHI-PROJECT-25462614, KAKENHI-PROJECT-25670506, KAKENHI-PROJECT-25830122
[Journal Article] 特集がん免疫学と免疫療法の新展開 7.分子標的薬を用いたがん免疫応答の制御2012
- Author(s)
  谷口智憲、西尾浩、里見良輔、川村直、小林明日香、河上裕
- Journal Title
  
  血液フロンティア
  
  Volume: 22 Pages: 1229-1238
- URL
  https://www.iyaku-j.com/iyakuj/system/M2-1/summary_viewer.php?trgid=25341
- Data Source
  KAKENHI-PROJECT-23791293
[Journal Article] 【がん免疫学と免疫療法の新展開】がん免疫病態と免疫動態の評価2012
- Author(s)
  河上裕, 谷口智憲, 中村公子, 川瀬芳恵, 野路しのぶ, 大泉梓, 南雲春菜, 長谷川舞, 徐明利, 岡本正人, 桜井敏晴, 藤田知信
- Journal Title
  
  血液フロンティア
  
  Volume: 22 Pages: 1183-1190
- Data Source
  KAKENHI-PROJECT-24591635
[Journal Article] 特集がん免疫学と免疫療法の新展開 1.がん免疫病態と免疫動態の評価2012
- Author(s)
  河上裕、谷口智憲、中村公子、川瀬芳恵、野路しのぶ、大泉梓、南雲春菜、長谷川舞、徐明利、岡本正人、桜井敏晴、藤田知信
- Journal Title
  
  血液フロンティア
  
  Volume: 22 Pages: 1183-1190
- URL
  https://www.iyaku-j.com/iyakuj/system/M2-1/summary_viewer.php?trgid=253355
- Data Source
  KAKENHI-PROJECT-23791293
[Journal Article] Fibroblast Growth Factor-2 Is an Important Factor that Maintains Cellular Immaturity and Contributes to Aggressiveness of Osteosarcoma2012
- Author(s)
  Shimizu T., et al
- Journal Title
  
  Mol Cancer Res
  
  Volume: 10(3) Issue: 3 Pages: 454-468
- DOI
  10.1158/1541-7786.mcr-11-0347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06969, KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-22241052, KAKENHI-PROJECT-22700865, KAKENHI-PROJECT-23790376, KAKENHI-PROJECT-23791293, KAKENHI-PROJECT-24590360
[Journal Article] Immune suppression and resistance mediated by constitutive activation of Wnt/β-catenin signaling in human melanoma cells2012
- Author(s)
  Yaguchi T.
- Journal Title
  
  J Immunol.
  
  Volume: 189 Issue: 5 Pages: 2110-2117
- DOI
  10.4049/jimmunol.1102282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501025, KAKENHI-PROJECT-23240128, KAKENHI-PROJECT-23659554, KAKENHI-PROJECT-23791293, KAKENHI-PROJECT-24501358, KAKENHI-PROJECT-24591635, KAKENHI-PROJECT-24592532
[Journal Article] がん免疫病態と免疫動態の評価:特集「がん免疫学と免疫療法の新展開」2012
- Author(s)
  河上裕、谷口智憲、中村公子、川瀬芳恵、野路しのぶ、大泉梓、南雲春菜、長谷川舞、徐明利、岡本正人、桜井敏晴、藤田知信
- Journal Title
  
  血液フロンティア
  
  Volume: 22(8) Pages: 1183-1190
- Data Source
  KAKENHI-PROJECT-23659554
[Journal Article] 分子標的薬を用いたがん免疫応答の制御2012
- Author(s)
  谷口智憲
- Journal Title
  
  血液フロンティア
  
  Volume: 22 Pages: 1229-1238
- Data Source
  KAKENHI-PROJECT-23791293
[Journal Article] 樹状細胞制御による抗腫瘍免疫増強2011
- Author(s)
  川村直, 宮崎潤一郎, 梶原-岩田知子, 谷口智憲, 河上裕
- Journal Title
  
  胆と膵
  
  Volume: 32 Pages: 123-127
- Data Source
  KAKENHI-PROJECT-21890247
[Journal Article] SEREX法による腫瘍抗原の単離と免疫療法への応用2011
- Author(s)
  宮崎潤一郎, 川村直, 梶原-岩田知子, 谷口智憲, 河上裕
- Journal Title
  
  細胞
  
  Volume: 43 Pages: 4-7
- Data Source
  KAKENHI-PROJECT-21890247
[Journal Article] The mechanisms of cancer immunoescape and development of overcoming strategies2011
- Author(s)
  Yaguchi T, et al
- Journal Title
  
  Int J Hematol
  
  Volume: 93(3) Issue: 3 Pages: 294-300
- DOI
  10.1007/s12185-011-0799-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06969, KAKENHI-PROJECT-21590445, KAKENHI-PROJECT-21591445, KAKENHI-PROJECT-23791293
[Journal Article] The mechanisms of cancer immunoescape and development of overcoming strategies.2011
- Author(s)
  Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Ueda R, Iwata-Kajihara T, Nishio H, Kawamura N, Kawakami Y.
- Journal Title
  
  Int J Hematol 93
  
  Pages: 294-300
- NAID
  10029533724
- URL
  http://www.springerlink.com/content/c478p246673x144p/fulltext.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890247
[Journal Article] 癌微小環境におけるPD-L1/PD-1による免疫抑制病態とその是正2011
- Author(s)
  川村直、谷口智憲、桜井敏晴、河上裕
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 56 Pages: 1-6
- URL
  http://www.kahyo.com/item/M201107-561
- Data Source
  KAKENHI-PROJECT-23791293
[Journal Article] SEREX法によるヒト腫瘍抗原の単離と免疫療法への応用2011
- Author(s)
  宮崎潤一郎、川村直、梶原-岩田知子、谷口智憲、河上裕
- Journal Title
  
  細胞
  
  Volume: 43 Pages: 88-91
- URL
  http://hokuryukan-ns.co.jp/magazines/archives/2011/02/20113_2.html
- Data Source
  KAKENHI-PROJECT-23791293
[Journal Article] ヒトがん細胞に対する免疫応答機構と免疫制御の可能性2011
- Author(s)
  河上裕、小室美紗、小林明日香、梶原-岩田知子、宮崎潤一郎、川村直、谷口智憲.
- Journal Title
  
  腫瘍内科
  
  Volume: 8 Pages: 409-416
- URL
  http://www.kahyo.com/item/ON201111-085
- Data Source
  KAKENHI-PROJECT-23791293
[Journal Article] 特集「ヒト誕生・老化・疾患を運ぶエクソソーム」癌細胞由来エクソソームによる免疫系への作用とその臨床応用2011
- Author(s)
  植田良、Li Qian、中村公子、谷口智憲、宮崎潤一郎、川村直、河上裕
- Journal Title
  
  実験医学
  
  Volume: 29 Pages: 410-414
- URL
  https://www.yodosha.co.jp/jikkenigaku/book/9784758100687/
- Data Source
  KAKENHI-PROJECT-23791293
[Journal Article] The mechanisms of cancer immunoescape and development of overcoming strategies.2011
- Author(s)
  Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Ueda R, Iwata-Kajihara T, Nishio H, Kawamura N, Kawakami Y
- Journal Title
  
  International Journal of Hematology
  
  Volume: 93 Pages: 294-300
- NAID
  10029533724
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890247
[Journal Article] 癌微小環境におけるPD-L1/PD-1による免疫抑制病態とその是正2011
- Author(s)
  川村直、谷口智憲、桜井敏晴、河上裕
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 56 Pages: 1-6
- Data Source
  KAKENHI-PROJECT-23240128
[Journal Article] 特集:膵癌・胆道癌に対する免疫治療、ワクチン療法の新展開樹状細胞抑制による抗腫瘍免疫増強2011
- Author(s)
  川村直、宮崎潤一郎、梶原-岩田知子、谷口智憲、河上裕
- Journal Title
  
  胆と膵
  
  Volume: 32 Pages: 123-127
- URL
  http://www.igakutosho.co.jp/magazine/t_s/2011/zt3202.html
- Data Source
  KAKENHI-PROJECT-23791293
[Journal Article] 癌細胞由来エクソソームによる免疫系への作用とその臨床応用2010
- Author(s)
  植田良, LiQian, 中村公子, 谷口智憲, 宮崎潤一郎, 川村直, 河上裕
- Journal Title
  
  実験医学
  
  Volume: 29 Pages: 410-414
- Data Source
  KAKENHI-PROJECT-21890247
[Journal Article] Emerging concepts in biomarker discovery ; The US-Japan workshop on immunological molecular markers in oncology.2009
- Author(s)
  Tahara H, Yaguchi T, et al.
- Journal Title
  
  J Transl Med. 7
  
  Pages: 45-45
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/19534815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890247
[Journal Article] Immunosuppression through constitutively activated NF-κB signaling in human ovarian cancer and its reversal by a NF-κB inhibitor
- Author(s)
  Nishio H, Yaguchi T, Sugiyama J, SumimotoH, UmezawaK, Iwata T, Susumu N, Fujii T, KawamuraN, KobayashiA, Park JH, Aoki D, Kawakami Y
- Journal Title
  
  British Journal of Cancer
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240128
[Patent] 悪性黒色腫の診断マーカー、ヒスタチン－１タンパク質の機能抑制物質を含有する医薬組成物、および、免疫抑制剤2011
- Inventor(s)
  谷口智憲, 河上裕
- Industrial Property Rights Holder
  谷口智憲, 河上裕
- Filing Date
  2011
- Overseas
- Data Source
  KAKENHI-PROJECT-23791293
[Patent] MMの診断マーカー、ヒスタチン-1タンパク質の機能抑制物質を含有する医薬組成物、および、免疫抑制剤2011
- Inventor(s)
  谷口智憲河上裕
- Industrial Property Rights Holder
  谷口智憲河上裕
- Filing Date
  2011-08-18
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] Analysis of intertumoral and intratumoral heterogeneity based on molecular subtypes in clear cell renal cell carcinoma reveals immune suppressive phenotype of the angiogenesis-related immune signatures.2024
- Author(s)
  Katsuhiro Itoh, Tomonori Yaguchi, Kenji Chamoto, Takayuki Sumiyoshi, Yuki Kita, Takashi Kobayashi, Tasuku Honjo.
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02785
[Presentation] グリピカン-1を標的としたキメラ抗原受容体遺伝子導入T細胞の開発2024
- Author(s)
  加藤大貴, 井口貴瑛, 岩田卓, 加藤侑希, 守井賢二, 世良田聡, 仲哲治, 西村亮平, 中川貴之, 谷口智憲, 河上裕
- Organizer
  2024年がん関連三学会Rising Starネットワーキング発表会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03141
[Presentation] 淡明細胞型腎細胞癌における分子サブタイプに特徴的な免疫微小環境の解析.2023
- Author(s)
  伊藤克弘、谷口智憲、茶本健司、住吉崇幸、北悠希、小林恭、本庶佑
- Organizer
  第27回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-21H02785
[Presentation] Current state of mouse models and possible use of non-rodent companion animal models for cancer immunology research2022
- Author(s)
  谷口智憲
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02785
[Presentation] 免疫賦活療法の功罪2022
- Author(s)
  谷口智憲
- Organizer
  第50回日本臨床免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02785
[Presentation] がん免疫療法の最近の動向2021
- Author(s)
  谷口智憲
- Organizer
  臨床免疫学会主催　アニュアルエビデンスレビュー2021（AER2021）
- Invited
- Data Source
  KAKENHI-PROJECT-18K08309
[Presentation] 複合がん免疫療法の開発2021
- Author(s)
  谷口智憲
- Organizer
  第37回　日本皮膚悪性腫瘍学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02785
[Presentation] 固形がんに対するCAR-T細胞療法の開発2020
- Author(s)
  谷口智憲、加藤大貴、守井賢二、世良田聡、仲哲治、河上裕
- Organizer
  第19回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08309
[Presentation] がん免疫療法の最近の動向2020
- Author(s)
  谷口智憲
- Organizer
  第48回日本臨床免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08309
[Presentation] CARTと免疫チェックポイント阻害薬の併用2019
- Author(s)
  1.Tomonori Yaguchi, Daiki Kato, Kenji Morii, Satoshi Serada, Tetsuji Naka, Yutaka Kawakami
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08309
[Presentation] 抗PD-1抗体により長期安定後に悪化した病巣のメラノーマ細胞とTILの解析2018
- Author(s)
  猪爪隆史、谷口智憲、河上裕、川村龍吉
- Organizer
  第22回日本がん免疫学会
- Data Source
  KAKENHI-PROJECT-18K08309
[Presentation] IMMUNE MODULATION OF THE TUMOR MICROENVIRONMENT FOR ENHANCING THE CANCER IMMUNOTHERAPIES2018
- Author(s)
  Tomonori Yaguchi
- Organizer
  The 3rd INTER-ACADEMY CANCER SYMPOSIUM (KEIO-NCC GCSP Communications in Cancer Science)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08309
[Presentation] New humanized mouse models to investigate in vivo interaction of immune system and human cancer.2018
- Author(s)
  Tomonori Yaguchi
- Organizer
  2nd Annual HuNIT (Humanized NOG mice for ImmunoTherapy) Platform Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08309
[Presentation] A BRAF inhibitor and a Toll-like receptor 7 agonist synergistically enhanced anti-tumor immune resonses depending on CD8+ T cell2017
- Author(s)
  Nakamura Kenta, Yaguchi Tomonori, Murata Masashi, Ota Yosuke, Kiniwa Yukiko, Okuyama Ryuhei, Kawakami Yutaka.
- Organizer
  The 42thAnnual Meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] IL-8 has a negative role on tumor infiltrating CD8+T cells in various cancers.2017
- Author(s)
  Sayem Mohammad A, Yaguchi Tomonori, Noji Shinobu, Iwata Takashi, Fujita Tomonobu, Kawakami Yutaka.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] CSF-1受容体阻害による腫瘍関連マクロファージ制御を介したPD-1阻害療法の抵抗性改善と治療効果増強2017
- Author(s)
  田宮将樹、守井賢二、谷口智憲、河上裕
- Organizer
  第45回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] 癌微小環境における免疫回避抑制機構とその克服法2017
- Author(s)
  谷口智憲、藤田知信、河上裕
- Organizer
  第26回日本がん転移学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] スタチン系製剤はmTORC1を介して制御性T細胞を制御し抗腫瘍免疫応答を増強する2017
- Author(s)
  坪田欣也、谷口智憲、守井賢二、河上裕
- Organizer
  第21回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] 4-1BB刺激は免疫チェックポイント阻害と相乗的にメラノーマ特異的CTLの活性を増強する2017
- Author(s)
  猪爪隆史、谷口智憲、河上裕
- Organizer
  第21回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] Reversal of anti-PD-1/PD-L1 therapy resistance by modulation of tumor-associated macrophages using CSF-1 receptor blockade.2017
- Author(s)
  Tamiya Masaki, Yaguchi Tomonori, Morii Kenji, Kawakami Yutaka
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] Immunobiology and immunotherapy for gynecological cancers2017
- Author(s)
  Yutaka Kawakami, Tomonori Yaguchi, Taeko Hayakwa, Kinya Tsubota, Juri Sugiyama, Takashi Nishio, Taku Iwata, Tomonobu Fujita, Daisuke Aoki.
- Organizer
  The 5thBiennial Meeting of Asian Society of Gynecologic Oncology
- Invited
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] スタチン系製剤は制御性T細胞を抑制し抗腫瘍免疫応答を増強する2017
- Author(s)
  坪田欣也、谷口智憲、後藤浩、河上裕
- Organizer
  第45回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] Immunomodulation of ovarian clear cell carcinoma by targeting HNF-1β-NH-kB-IL6 pathway enhances anti-tumor immunity.2017
- Author(s)
  Kagawa Masaki, Yaguchi Tomonori, Morii Kenji, Takise Yoshiaki, Nishio Hiroshi, Sugiyama Juri, Iwata Takashi, Fujita Tomonobu, Kawakami Yutaka
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] 新規腫瘍抗原グリピカン-1を標的としたキメラ抗原受容体遺伝子導入T細胞は正常組織への副作用なく強い抗腫瘍活性を示す2017
- Author(s)
  加藤大貴、谷口智憲、守井賢二、世良田聡、仲哲治、中川貴之、西村亮平、河上裕
- Organizer
  第21回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] ヒト腫瘍免疫学の最近の進歩とがん免疫療法の展望2016
- Author(s)
  谷口智憲、河上裕
- Organizer
  第79回日本皮膚科学会東京･東部支部合同学術集会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2016-02-20
- Invited
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] 既存薬を用いた、がん微小環境の免疫抑制解除による、免疫チェックポイント阻害薬の抗腫瘍効果の増強2016
- Author(s)
  谷口智憲、中村謙太、早川妙香、坪田欣也、河上裕
- Organizer
  第20回日本がん免疫学会
- Place of Presentation
  大阪国際交流センター(大阪府大阪市)
- Year and Date
  2016-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] 症例ごとの免疫状態評価に基づいた個別化がん免疫療法2016
- Author(s)
  河上裕、藤田知信、谷口智憲
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-07
- Invited
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] がんシグナル伝達分子阻害薬による免疫抑制の解除2016
- Author(s)
  谷口智憲、岩田卓、里見良輔、守井賢二、西尾浩、杉山重里、中村謙太、香川昌樹、藤田知信、河上裕
- Organizer
  第20回日本がん免疫学会
- Place of Presentation
  大阪国際交流センター(大阪府大阪市)
- Year and Date
  2016-07-29
- Invited
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] がんシグナル伝達分子阻害薬を用いた、がん微小環境の免疫抑制解除による、がん免疫療法の増強2016
- Author(s)
  谷口智憲、里見良輔、西尾浩、早川妙香、坪田欣也、河上裕
- Organizer
  第44回日本臨床免疫学会総会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2016-09-08
- Invited
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] Combined cancer immunotherapies using molecular-targeting drugs.2015
- Author(s)
  Yaguchi T.
- Organizer
  The 4th CSI/JSI/KAI Joint Symposium on Immunology(日本･中国･韓国合同シンポジウム)
- Place of Presentation
  蘇州(中国)
- Year and Date
  2015-09-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] Co-blockade of TIGIT and PD-1 signals in tumor-infiltrating cytotoxic T lymphocytes is an effective antimelanoma therapy2015
- Author(s)
  Takashi Inozume, Tomonori Yaguchi, Junpei Furuta, Kazutoshi Harada, Yutaka Kawakami, Shinji Shimada
- Organizer
  第40回日本研究皮膚科学会
- Place of Presentation
  岡山コンベンションセンター(岡山県岡山市)
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] ヒトがん微小環境の免疫学的評価　＝T細胞の腫瘍浸潤を規定する因子の解析＝2015
- Author(s)
  谷口智憲
- Organizer
  Human immunology forum
- Place of Presentation
  京王プラザホテル札幌(北海道札幌市)
- Year and Date
  2015-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] CD155-TIGIT interaction is an immune checkpoint regulating antimelanoma TIL responses2015
- Author(s)
  Inozume Takashi, Yaguchi Tomonori, Kawakami Yutaka, Shimada Shinji
- Organizer
  がん免疫療法・マクロファージ国際会議2015
- Place of Presentation
  東京大学伊藤国際学術センター内伊藤謝恩ホール(東京都文京区)
- Year and Date
  2015-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] CD155/TIGITシグナルは悪性黒色腫において腫瘍抗原特異的T細胞応答をエフェクターフェーズで制御する2015
- Author(s)
  谷口智憲、猪爪隆史、古田潤平、原田和俊、島田眞路、河上裕
- Organizer
  第43回日本臨床免疫学会総会,
- Place of Presentation
  神戸国際会議場(兵庫県神戸市)
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] 子宮頸がん局所に浸潤するT細胞を用いた免疫療法の開発2015
- Author(s)
  Sunthamala Nuchsupha、西尾浩、谷口智憲、岩田卓、河上裕、青木大輔
- Organizer
  婦人科がん分子標的研究会
- Place of Presentation
  美ヶ原温泉ホテル(長野県松本市）
- Year and Date
  2015-07-17
- Data Source
  KAKENHI-PROJECT-25462614
[Presentation] The screening for drugs which augment anti-tumor activity of tumor specific effector T cells2015
- Author(s)
  Takise Yoshiaki, Yaguchi Tomonori, Sunthamala Nuchsupha, Kawakami Yutaka
- Organizer
  第44回日本免疫学会
- Place of Presentation
  札幌コンベンションセンター(北海道札幌市)
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K09783
[Presentation] Cancer-induced differential immune-status among patients and it'smodification for effective cancer treatment2014
- Author(s)
  Kawakami Y, Popivanova B, Nagumo H, Muramatsu R, Shinobu Noji, Xu M, Fujita T, Okamoto M, Sakurai T, Sugiyama J, Hayakawa T, Satomi R, Nishio H, Yaguchi T
- Organizer
  Cold Spring Harbor Asia, Frontiers of Immunology in Health and Diseases
- Place of Presentation
  Suzhou, China　(中国）
- Year and Date
  2014-09-04
- Invited
- Data Source
  KAKENHI-PROJECT-24591635
[Presentation] クルクミン併用による免疫抑制改善効果を介した免疫チェックポイント阻害療法の効果増強2014
- Author(s)
  早川妙香、杉山重里、谷口智憲、今泉厚、河上裕
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] Enhanced anti-tumor effects of the PD-1/PD-L1 blockade by combining a highly absorptive form of NF-kB/STAT3 inhibitor curcumin.2014
- Author(s)
  Hayakawa T, Sugiyama J, Yaguchi T, Imaizumi A, Kawakami Y.
- Organizer
  The 29th Society for Immunotherapy of Cancer Annual Meeting
- Place of Presentation
  National Harbor, MD, USA
- Year and Date
  2014-11-06
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] Cancer-induced differential immune-status among patients and it'smodification for effective cancer treatment2014
- Author(s)
  Kawakami Y, Popivanova B, Nagumo H, Muramatsu R, Shinobu Noji, Xu M, Fujita T, Okamoto M, Sakurai T, Sugiyama J, Hayakawa T, Satomi R, Nishio H, Yaguchi T.
- Organizer
  Cold Spring Harbor Asia,Frontiers of Immunology in Health and Diseases
- Place of Presentation
  Suzhou, China
- Year and Date
  2014-09-04
- Invited
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] CD155-TIGIT interactiono is an immune checkpoit regulating antimelanoma immune responses2014
- Author(s)
  猪爪隆史、谷口智憲、古田潤平、原田和俊、伊藤守、河上裕、島田眞路
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  ひめぎんホール、愛媛県
- Year and Date
  2014-07-31
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] Development of Immunotherapy based on the immunological chracteristics of Gynecologic Cancers2014
- Author(s)
  Kawakami Y, Sugiyama J, Nishio H, Hayakawa T, Iwata T, Aoki D, Yaguchi T.
- Organizer
  The 19thJapan-Korea Cancer Research Workshop
- Place of Presentation
  Jeju, Korea
- Year and Date
  2014-11-29
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] 局所性Renin-Angiotensin systemの阻害による、がん関連線維芽細胞や骨髄系免疫細胞の制御を介したPD-1/PD-L1免疫チェックポイント阻害療法の効果増強2014
- Author(s)
  中村謙太、谷口智憲、大村学、小林明日香、川村直、杉山重里、桜井敏晴、木庭幸子、奥山隆平、河上裕
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  ひめぎんホール (愛媛)
- Year and Date
  2014-08-01
- Data Source
  KAKENHI-PROJECT-24591635
[Presentation] Effective cancer immunotherapy for human melanoma by combination of BRAF inhibitor and Toll-like receptor 7 agonist.2014
- Author(s)
  Nakamura K, Yaguchi T, Popivanova B, Murata M, Mikoshiba A, Kiniwa Y, Okuyama R, Kawakami Y.
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] 高吸収クルクミン併用による免疫抑制改善効果を介した免疫チェックポイント阻害療法の効果増強2014
- Author(s)
  早川妙香、杉山重里、今泉厚、谷口智憲、河上裕
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  ひめぎんホール、愛媛県
- Year and Date
  2014-08-01
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] 分子標的薬併用による効果的な個別化がん免疫療法2014
- Author(s)
  河上裕、早川妙香、中村謙太、ポピバノバボリヤナ、杉山重里、西尾浩、谷口智憲
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] ヒト末梢血移入マウスMHC class I/IIノックアウトNOGマウスを用いたヒト腫瘍免疫応答のin vivo解析2014
- Author(s)
  谷口智憲、小林明日香、片野いくみ、河裕遥、猪爪隆史、伊藤守、河上裕
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  ひめぎんホール、愛媛県
- Year and Date
  2014-07-31
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] 局所性Renin-Angiotensin systemの阻害による、がん関連線維芽細胞や骨髄系免疫細胞の制御を介したPD-1/PD-L1免疫チェックポイント阻害療法の効果増強2014
- Author(s)
  中村謙太、谷口智憲、大村学、小林明日香、川村直、杉山重里、桜井敏晴、木庭幸子、奥山隆平、河上裕
- Organizer
  第42回日本臨床免疫学会
- Place of Presentation
  京王プラザホテル（東京）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24591635
[Presentation] 局所性Renin-Angiotensin systemの阻害による、がん関連線維芽細胞や骨髄系免疫細胞の制御を介したPD-1/PD-L1免疫チェックポイント阻害療法の効果増強2014
- Author(s)
  中村謙太、谷口智憲、大村学、小林明日香、川村直、杉山重里、桜井敏晴、木庭幸子、奥山隆平、河上裕
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  ひめぎんホール、愛媛県
- Year and Date
  2014-08-01
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] 局所性Renin-Angiotensin systemの阻害による、がん関連線維芽細胞や骨髄系免疫細胞の制御を介したPD-1/PD-L1免疫チェックポイント阻害療法の効果増強2014
- Author(s)
  中村謙太、谷口智憲、大村学、小林明日香、川村直、杉山重里、桜井敏晴、木庭幸子、奥山隆平、河上裕
- Organizer
  第42回日本臨床免疫学会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] Systemic administration of a highly absorptive form of curcumin reverses cancer-induced immunosuppression through inhibiting NF-kB and STAT32013
- Author(s)
  Taeko Hayakawa, Juri Sugiyama, Yaguchi Tomonori, Atsushi Imaizumi, Yutaka Kawakami
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ、千葉県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Different immunoenvironments among cancer patients-Possible Biomarkers and modification for effective cancer treatments2013
- Author(s)
  Kawakami Y, Xu M, Nagumo H, Fujita T, Okamoto M, Sakurai T, Noji S, Sugiyama J, Hayakawa T, Nishio H, Yaguchi T
- Organizer
  Cold Spring Harbor Conferences Asia, Tumor Immunolgy & Immunotherapy
- Place of Presentation
  Suzhou Dushu Lake Conference Center Suzhou, China
- Year and Date
  2013-10-29
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Different immunoenvironments among cancer patients-Possible Biomarkers and modification for effective cancer treatments.2013
- Author(s)
  Yutaka Kawaami, Mingli Xu, haruna Nagumo, Tomonobu Fujita, Masato Okamoto, Toshiharu Sakurai, Shinobu Noji, Juri Sugiyama, Taeko Hayakawa, Hiroshi Nishio, Tomonori Yaguchi,
- Organizer
  2013Cold Spring Harbor Conferences Asia, Tumor Immunolgy & Immunotherapy
- Place of Presentation
  Suzhou Dushu Lake Conference Center　蘇州、中国
- Invited
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] 局所性Renin-Angiotensin systemは免疫抑制的がん微小環境の構築に関与する2013
- Author(s)
  中村　謙太、谷口　智憲、大村　学、小林　明日香、川村　直、杉山　重里、桜井　敏晴、木庭　幸子、奥山　隆平、河上　裕
- Organizer
  第17回　日本がん免疫学会総会
- Place of Presentation
  宇部、山口、日本
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] EGFR-TKIs (EGFR-tyrosin kinase inhibitors) enhance anti-tumor immune responses in an EGFR independent manner2013
- Author(s)
  Yaguchi T, Satomi R, Kobayashi A, Soejima K, Betsuyaku T, Kawakami Y
- Organizer
  第72回　日本癌学会学術総会
- Place of Presentation
  横浜、神奈川、日本
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] がん微小環境の免疫病態の理解とその制御2013
- Author(s)
  河上裕、徐明利、谷口智憲、藤田知信
- Organizer
  第51回日本癌治療学会
- Place of Presentation
  国立京都国際会館・グランドプリンスホテル、京都府
- Invited
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Myosin 1bは頭頸部癌で過剰発現し、腫瘍細胞の浸潤・遊走・転移を促進する2013
- Author(s)
  大村学、辻川敬裕、谷口智憲、川村直、中村謙太、杉山重里、三上修治、中野宏、島田剛敏、久育男、河上裕
- Organizer
  第72回　日本癌学会学術総会
- Place of Presentation
  横浜、神奈川、日本
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] NF-kBシグナルを標的とした卵巣癌局所における免疫抑制環境の改善と治療への応用2013
- Author(s)
  岩田卓、田中京子、杉山重里、西尾浩、平尾薫丸、森定徹、早川妙香、谷口智憲、河上裕、青木大輔
- Organizer
  第72回　日本癌学会学術総会
- Place of Presentation
  横浜、神奈川、日本
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] Different immunoenvironments among cancer patients-Possible Biomarkers and modification for effective cancer treatments.2013
- Author(s)
  Yutaka Kawaami, Mingli Xu, haruna Nagumo, Tomonobu Fujita, Masato Okamoto, Toshiharu Sakurai, Shinobu Noji, Juri Sugiyama, Taeko Hayakawa, Hiroshi Nishio, Tomonori Yaguchi,
- Organizer
  2013Cold Spring Harbor Conferences Asia, Tumor Immunolgy & Immunotherapy,
- Place of Presentation
  Suzhou Dushu Lake Conference Center　蘇州、中国
- Invited
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Immunosuppresive roles of local renin angiotensin system (RAS) in cancer microenvironments.2013
- Author(s)
  Nakamura Kenta, Tomonori Yaguchi, Gaku Ohmura, Asuka Kobayasi, Naosi Kawamura, Juri Sugiyama, Toshiharu Sakurai, Yukiko Kiniwa, Ryuhei Okuyama, Yutaka Kawakami
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  パシフィコ横浜　（横浜）
- Data Source
  KAKENHI-PROJECT-24591635
[Presentation] 卵巣明細胞腺癌においてHNF-1βは腫瘍免疫の抑制に関与する2013
- Author(s)
  杉山重里、谷口智憲、川村直、中村謙太、大村学、岩田卓、藤田知信、青木大輔、河上裕
- Organizer
  第72回日本癌学会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] MHC class I/II deficient NOG mice are useful for analysis of human T/B cell responses for human tumor immunology research2013
- Author(s)
  Yaguchi T, Kobayashi A, Ka Y, Katano I, Ito M, Kawakami Y
- Organizer
  SiTC 2013 28th annual meeting
- Place of Presentation
  National Harbor, MD, USA
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] EGFR-チロシンキナーゼ阻害薬はEGFR非依存的に抗腫瘍免疫応答を増強する2013
- Author(s)
  谷口智憲、里見良輔、小林明日香、守井賢二、副島研造、別役智子、河上裕
- Organizer
  第72回日本癌学会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] ヒト卵巣癌におけるNF-κB活性化による免疫抑制誘導とNF-κB阻害剤による改善2013
- Author(s)
  西尾浩、谷口智憲、住本秀敏、梅澤一夫、杉山重里、岩田卓、青木大輔、河上裕
- Organizer
  第72回日本癌学会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Administration of a highly absorptive form ofcurcumin augments anti-tumor immune responses through reversal of cancer-induced immunosuppression via NF-kB and STAT3 inhibition.2013
- Author(s)
  Taeko Hayakawa, Juri Sugiyama, Tomonori Yaguchi, Atsushi Imaizumi, Yutaka Kawakami.
- Organizer
  2013Cold Spring Harbor Conferences Asia, Tumor Immunolgy & Immunotherapy
- Place of Presentation
  Suzhou Dushu Lake Conference Center　蘇州、中国
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] NF-kBシグナルを標的とした卵巣癌局所における免疫抑制環境の改善と治療への応用2013
- Author(s)
  岩田卓、田中京子、杉山重里、西尾浩、平尾薫丸、森定徹、早川妙香、谷口智憲、河上裕、青木大輔
- Organizer
  第72回日本癌学会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Immunosuppressive roles of local renin–angiotensin system (RAS) in cancer microenvironments2013
- Author(s)
  Nakamura K, Yaguchi T, Ohmura G. Kobayashi A Kawamura N, Sugiyama J, Sakurai T, Kiniwa Y, Okuyama R, Kawakami Y
- Organizer
  第72回　日本癌学会学術総会
- Place of Presentation
  横浜、神奈川、日本
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] ヒト卵巣明細胞腺癌に発現するHNF-1βは免疫抑制的がん微小環境の構築に関与2013
- Author(s)
  杉山重里、谷口智憲、川村直、中村謙太、大村学、岩田卓、藤田智信、青木大輔、河上裕
- Organizer
  第17回日本がん免疫学会
- Place of Presentation
  ANAクラウンプラザホテル宇部、山口県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Tumor immunology Different tumor immunoenvironments among patients: Biomarkers and their modification for cancer treatments2013
- Author(s)
  Kawakami Yutaka, Xu Mingli, Nagumo Haruna, Fujita Tomonobu, Okamoto Masato, Sakurai Toshiharu, Noji Shinobu, Sugiyama Juri, Hayakawa Taeko, Nishio Hiroshi, Yaguchi Tomonori
- Organizer
  第42回日本免疫学会総会
- Place of Presentation
  幕張メッセ　（千葉）
- Data Source
  KAKENHI-PROJECT-24591635
[Presentation] がん微小環境における制御性免疫細胞の誘導とその制御2013
- Author(s)
  谷口智憲、中村謙太、杉山重里、西尾浩、川村直、里見良輔、河上裕
- Organizer
  第41回日本臨床免疫学会
- Place of Presentation
  海峡メッセ下関、山口県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Systemic administration of a highly absorptive form of curcumin reverses cancer-induced immunosuppression through inhibiting NF-kB and STAT32013
- Author(s)
  Hayakawa T, Sugiyama J, Yaguchi T, Imaizumi A, Kawakami Y
- Organizer
  第42回　日本免疫学会総会
- Place of Presentation
  幕張、千葉、日本
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] Human PBMC transferred murine MHC class I/II deficient NOG mice are useful for analysis of human T/B cell responses2013
- Author(s)
  Yaguchi T, Kobayashi A, Ka Y, Katano I, Ito M, Kawakami Y
- Organizer
  第42回　日本免疫学会総会
- Place of Presentation
  幕張、千葉、日本
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] ヒトがん免疫病態の解明と免疫バイオマーカーの同定2013
- Author(s)
  河上裕、徐明利、谷口智憲、野路しのぶ、南雲春菜、岡本正人、桜井敏晴、藤田知信、鳥越俊彦、佐藤昇志、中面哲也、垣見和宏、池田裕明、珠玖洋、奥野清隆、杉浦史哲、中山睿一、硲彰一、岡正朗、伊東恭悟
- Organizer
  第17回日本がん免疫学会
- Place of Presentation
  ANAクラウンプラザホテル宇部、山口県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] ifferent tumor immunoenvironments among patients: Biomarkers and their modification for cancer treatment.2013
- Author(s)
  Kawakami Yutaka, Xu Mingli, Nagumo Haruna, Fujita Tomonobu , Okamoto Masato, Sakurai Toshiharu, Noji Shinobu, Sugiyama Juri, Hakawa Taeko, Nishio Hiroshi, Yaguchi Tomonori,
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ、千葉県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] HNF-1β is an upstream molecule in immunosuppression by human ovarian clear cell carcinoma (OCCC)2013
- Author(s)
  Sugiyama J, Yaguchi T, Kawamura N, Nakamura K, Ohmura G. Iwata T, Fujita T, Aoki D, Kawakami Y
- Organizer
  第72回　日本癌学会学術総会
- Place of Presentation
  横浜、神奈川、日本
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] EGFR-TKIs (EGFR-tyrosin kinase inhibitors)は非小細胞肺癌と免疫担当細胞の両者に作用し抗腫瘍免疫応答を増強させる2013
- Author(s)
  里見良輔、谷口智憲、小林　明日香、副島研造、別役智子、河上裕
- Organizer
  第17回　日本がん免疫学会総会
- Place of Presentation
  宇部、山口、日本
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] STK24 mediates immunosuppressive and tumor promoting conditions in tumor microenvironment2013
- Author(s)
  川村直、住本秀敏、谷口智憲、辻川敬裕、守井賢二、小林明日香、河上裕
- Organizer
  第40回日本臨床免疫学会
- Place of Presentation
  京王プラザホテル、東京都
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] 癌微小環境におけるレニン・アンジオテンシンシステムの免疫抑制性の役割2013
- Author(s)
  中村謙太、谷口智憲、大村学、小林明日香、川村直、杉山重里、桜井敏晴、木庭幸子、奥山隆平、河上裕
- Organizer
  第72回日本癌学会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] 卵巣明細胞腺癌においてHNF-1βは腫瘍免疫の抑制に関与する2013
- Author(s)
  杉山重里、西尾浩、岩田卓、谷口智憲、青木大輔、河上裕
- Organizer
  第65回日本産科婦人科学会
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-25462614
[Presentation] CD155はメラノーマ細胞に発現され、PD-L1と協調的にメラノーマ特異的CTLの活性化を抑制する2013
- Author(s)
  猪爪隆史、古田潤平、谷口智憲、河上裕、島田眞路
- Organizer
  第17回日本がん免疫学会
- Place of Presentation
  ANAクラウンプラザホテル宇部、山口県
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] 悪性黒色腫に異所性に発現するHistatin-1は樹状細胞を抑制し、がん免疫回避に関与する2013
- Author(s)
  谷口智憲、栗原智樹、後藤康文、伊藤有毅、守井賢二、小林明日香、西尾浩、住本秀敏、河上裕
- Organizer
  第23回日本樹状細胞研究会
- Place of Presentation
  京都、京都、日本
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] IMMUNOSUPPRESSION THROUGH HNF-1β SIGNALING IN HUMAN OVARIAN CLEAR CELL CANCER2013
- Author(s)
  Hiroshi Nishio, Juri Sugiyama, Tomonori Yaguchi, Daisuke Aoki, Yutaka Kawakami,
- Organizer
  28th Society for Immunotherapy of Cancer
- Place of Presentation
  National Harbor, MD,　ワシントン、アメリカ
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] 局所性Renin-Angiotensin systemは免疫抑制的がん微小環境の構築に関与する2013
- Author(s)
  中村謙太、谷口智憲、大村学、小林明日香、川村直、杉山重里、桜井敏晴、木庭幸子、奥山隆平、河上裕
- Organizer
  第17回日本がん免疫学会
- Place of Presentation
  ANAクラウンプラザホテル宇部、山口県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Reversal of immunosuppression in ovarian cancer microenvironment by targeting NF-kB signal and its clinical application2013
- Author(s)
  Nishio H, Yaguchi T, Sumimoto H, Umezawa K, Sugiyama J, Iwata T, Aoki D, Kawakami Y
- Organizer
  第72回　日本癌学会学術総会
- Place of Presentation
  横浜、神奈川、日本
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] ヒト卵巣明細胞腺癌に発現するHNF-1βは免疫抑制的がん微小環境の構築に関与する2013
- Author(s)
  杉山重里、谷口智憲、川村直、中村謙太、大村学、岩田卓、藤田知信、青木大輔、河上裕
- Organizer
  第17回　日本がん免疫学会総会
- Place of Presentation
  宇部、山口、日本
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] ヒト卵巣癌における NF-κB活性化による免疫抑制誘導と NF-κB 阻害剤による改善2013
- Author(s)
  西尾浩、谷口智憲、住本秀敏、梅澤一夫、岩田卓、藤井多久磨、青木大輔、河上裕
- Organizer
  第72回日本癌学会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Data Source
  KAKENHI-PROJECT-25462614
[Presentation] ヒトがん免疫病態の解明と免疫バイオマーカーの同定2013
- Author(s)
  河上裕、徐明利、谷口智憲、野路しのぶ、南雲春菜、岡本正人、桜井敏晴、藤田知信、鳥越俊彦、佐藤昇志、中面哲也、垣見和宏、池田裕明、珠玖洋、奥野清隆、杉浦史哲、中山睿一、硲彰一、岡正朗、伊東恭悟,
- Organizer
  第17回日本がん免疫学会
- Place of Presentation
  ANAクラウンプラザホテル宇部、山口県
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] 悪性黒色腫に異所性に発現するHistatin-1は樹状細胞を抑制し、がん免疫回避に関与する2013
- Author(s)
  谷口智憲
- Organizer
  第23回日本樹状細胞研究会
- Place of Presentation
  国立京都国際会館、京都府
- Data Source
  KAKENHI-PROJECT-25670506
[Presentation] がん微小環境における抑制性免疫細胞の誘導とその制御2013
- Author(s)
  谷口　智憲、中村　謙太、杉山　重里、西尾　浩、川村　直、里見　良輔、河上　裕
- Organizer
  第41回　臨床免疫学会総会
- Place of Presentation
  下関、山口、日本
- Invited
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] EGFR-TKIs(EGFR-tyrosin kinase inhibitors)は非小細胞肺癌と免疫担当細胞の両者に作用し抗腫瘍免疫応答を増強させる2013
- Author(s)
  里見良輔、谷口智憲、小林明日香、副島研造、別所智子、河上裕
- Organizer
  第17回日本がん免疫学会
- Place of Presentation
  ANAクラウンプラザホテル宇部、山口県
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Altered Wnt/β-cateninsignal in human melanoma inducesimmunosuppressive and tumorpromoting tumor microenvironment2012
- Author(s)
  Yaguchi T
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] miR-221とmiR-222は免疫抑制性サイトカインの産生を介してヒト悪性黒色腫細胞による免疫抑制を促進する2012
- Author(s)
  宮崎潤一郎、植田良、谷口智憲、藤田知信、河上裕
- Organizer
  第71回日本癌学会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23659554
[Presentation] 悪性黒色腫で亢進するWnt/β-cateninシグナルは免疫抑制的で腫瘍を促進する微小環境を誘導する2012
- Author(s)
  谷口智憲、栗原智樹、後藤康文、伊藤有毅、守井賢二、小林明日香、西尾浩、住本秀敏、河上裕
- Organizer
  第71回日本癌学会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-24591635
[Presentation] Altered Wnt/β-catenin signal in human melanoma induces immunosuppressive and tumor promoting tumor microenvironment2012
- Author(s)
  Yaguchi T
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] 悪性黒色腫に異所性に発現するHistatin-1はin vivoで細胞運動能と免疫抑制能を亢進させる2012
- Author(s)
  谷口智憲
- Organizer
  第16回日本がん免疫学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] 悪性黒色腫に異所性に発現するHistatin-1はin vivoで細胞運動能と免疫抑制能を亢進させる2012
- Author(s)
  谷口智憲、栗原智樹、後藤康文、伊藤有毅、守井賢二、小林明日香、西尾浩、住本秀敏、河上裕
- Organizer
  第16回日本がん免疫学会
- Place of Presentation
  北海道大学学術交流会館
- Data Source
  KAKENHI-PROJECT-24591635
[Presentation] 悪性黒色腫に異所性に発現するHistatin-1は細胞運動能と免疫抑制能を亢進させる2011
- Author(s)
  谷口智憲、栗原智樹、後藤康文、伊藤有毅、守井賢二、小林明日香、西尾浩、住本秀敏、河上裕
- Organizer
  第15回日本がん免疫学会
- Place of Presentation
  大阪　千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] がん免疫逃避機構とその制御2011
- Author(s)
  河上裕、住本秀敏、岩田知子、川村直、谷口智憲、西尾浩、工藤千恵、塚本信夫
- Organizer
  第15回日本がん免疫学会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府)
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] Novel mouse models for analysis of in vivo interaction of immune system and human cancer2011
- Author(s)
  Tomonori Yaguchi, Asuka Kobayashi, Hiroshi Nishio, Tyoji Ito, Ikumi Katano, Kazuo Umezawa, Mamoru Ito, Yutaka Kawakami
- Organizer
  第40回日本免疫学会(招待講演)
- Place of Presentation
  千葉　幕張メッセ
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] CCL22/CCR4は癌細胞浸潤能増加によりヒト頭頸部扁平上皮癌のリンパ節転移に関与する2011
- Author(s)
  辻川敬裕、谷口智憲、小林明日香、植田良、塚本信夫、藤田知信、中野宏、島田剛敏、柳澤昭夫、河上裕
- Organizer
  第70回日本癌学会
- Place of Presentation
  愛知　名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] 悪性黒色腫に異所性に発現するHistatin-1は細胞運動能と免疫抑制能を亢進させる2011
- Author(s)
  谷口智憲
- Organizer
  第15回日本がん免疫学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] Analysis of human immune responses using newly developed murine MHC class I and II-deficient NOG mice by human PBMC inoculation2011
- Author(s)
  Tomonori Yaguchi, Asuka Kobayashi, Mamoru Ito, Ryoji Ito, Yutaka Kawakami
- Organizer
  3rd International Workshop on HUMANIZED MICE
- Place of Presentation
  Pittsburgh, Pennsylvania, USA
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] NGFRはIFN-g刺激でメラノーマ細胞上に発現増強されメラノーマ特異的T細胞からの認識を制御する2011
- Author(s)
  猪爪隆史、花田賢一、古田潤平、谷口智憲、河上裕、ローゼンバーグスティーブ、島田眞路、ヤングジェームス
- Organizer
  第15回日本がん免疫学会
- Place of Presentation
  大阪　千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] The ImmunosuppressiveRole of WNT/beta-catenin signals inmelanoma cancer microenvironments2011
- Author(s)
  Yaguchi T
- Organizer
  26th Annual Meeting Society forImmunotherapy of Cancer
- Place of Presentation
  North Bethesda,Maryland USA
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] 悪性黒色腫で異所性に発現するHistatin-1は細胞運動能と免疫抑制能を亢進させる2011
- Author(s)
  谷口智憲、栗原智樹、後藤康文、伊藤有毅、守井賢二、小林明日香、西尾浩、住本秀敏、河上裕
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] The Immunosuppressive Role of WNT/beta-catenin signals in melanoma cancer microenvironments2011
- Author(s)
  Tomonori Yaguchi, Yasufumi Goto, Tomoki Kurihara, Asuka Kobayashi, Kenji Morii, Hidetoshi Sumimoto, Yutaka Kawakami
- Organizer
  26th Annual Meeting Society for Immunotherapy of Cancer
- Place of Presentation
  North Bethesda, MD, USA
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] がん微小環境免疫抑制病態による転移促進とその制御2011
- Author(s)
  河上裕、工藤千恵、住本秀敏、塚本信夫、岩田知子、西尾浩、川村直、谷口智憲
- Organizer
  第70回日本癌学会(招待講演)
- Place of Presentation
  愛知　名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] The Immunosuppressive Role of WNT/beta-catenin signals in melanoma cancer microenvironments2011
- Author(s)
  Tomonori Yaguchi, et al
- Organizer
  26thAnnual Meeting Society for Immunotherapy of Cancer
- Place of Presentation
  North Bethesda, MD (USA)
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] ヒト卵巣癌におけるNF-κBの活性化は免疫抑制状態を誘導する2011
- Author(s)
  西尾浩、谷口智憲、住本秀敏、梅澤一夫、藤田知信、岩田卓、藤井多久磨、青木大輔、河上裕
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] ヒト卵巣癌におけるNF-κBの活性化は免疫抑制状態を誘導する2011
- Author(s)
  西尾浩、谷口智憲、住本秀敏、梅澤一夫、藤田知信、岩田卓、藤井多久磨、青木大輔、河上裕
- Organizer
  第70回日本癌学会
- Place of Presentation
  愛知　名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] 悪性黒色腫に異所性に発現するHistatin-1は細胞運動能と免疫抑制能を亢進させる2011
- Author(s)
  谷口智憲、栗原智樹、後藤康文、伊藤有毅、守井賢二、小林明日香、西尾浩、住本秀敏、河上裕
- Organizer
  第15回日本がん免疫学会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] 悪性黒色腫で異所性に発現するHistatin-1は細胞運動能と免疫抑制能を亢進させる2011
- Author(s)
  谷口智憲
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] がん免疫逃避機構とその制御2011
- Author(s)
  河上裕、住本秀敏、岩田知子、川村直、谷口智憲、西尾浩、工藤千恵、塚本信夫
- Organizer
  第15回日本がん免疫学会(招待講演)
- Place of Presentation
  大阪　千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] Novel mouse models foranalysis of in vivo interaction ofimmune system and human cancer2011
- Author(s)
  Yaguchi T
- Organizer
  第40回日本免疫学会
- Place of Presentation
  千葉(招待講演)
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] Role of IL6/IL8-NF-KB AXIS in the Immunosuppression and resistance to immunotherapy2011
- Author(s)
  Yutaka Kawakami, Hiroshi Nishio, Tomonori Yaguchi, Yoshie Kawase, Azusa Ohizumi, Shinobu Noji, Toshiharu Sakurai, Kazuo Umezawa, Tomonobu Fujita
- Organizer
  26th Annual Meeting Society for Immunotherapy of Cancer
- Place of Presentation
  North Bethesda, MD, USA
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] ヒトPBMC移入MHCノックアウトNOGマウスにおけるヒト免疫応答の解析2011
- Author(s)
  小林明日香、谷口智憲、伊藤亮治、片野いくみ、伊藤守、河上裕
- Organizer
  第40回日本免疫学会
- Place of Presentation
  千葉　幕張メッセ
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] Role of IL6/IL8-NF-KB AXIS in the Immunosuppression and resistance to immunotherapy2011
- Author(s)
  Kawakami Y, Nishio H, Yaguchi T, Kawase Y, Ohizumi A, Noji S, Sakurai T, Umezawa K, Fujita T
- Organizer
  26th Annual Meeting Society for Immunotherapy of Cancer
- Place of Presentation
  North Bethesda, MD, USA
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] NF-kB阻害剤の投与はヒト卵巣癌による免疫抑制病態を改善し、腫瘍の免疫学的排除効果を増強する2011
- Author(s)
  西尾浩、谷口智憲、藤田知信、杉山重里、岩田卓、守井賢二、青木大輔、河上裕
- Organizer
  第15回日本がん免疫学会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] NF-kB阻害剤の投与はヒト卵巣癌による免疫抑制病態を改善し、腫瘍の免疫学的排除効果を増強する2011
- Author(s)
  西尾浩、谷口智憲、藤田知信、杉山重里、岩田卓、守井賢二、青木大輔、河上裕
- Organizer
  第15回日本がん免疫学会
- Place of Presentation
  大阪　千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] 悪性黒色腫で異所性に発現するHistatin-1は細胞運動能と免疫抑制能を亢進させる2011
- Author(s)
  谷口智憲、栗原智樹、後藤康文、伊藤有毅、守井賢二、小林明日香、西尾浩、住本秀敏、河上裕
- Organizer
  第70回日本癌学会
- Place of Presentation
  愛知　名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] 腫瘍産生性TGF-βはセンチネルリンパ節において免疫抑制を誘導し、抗腫瘍免疫応答を抑制する2011
- Author(s)
  中村公子、谷口智憲、小林明日香、川村直、樋口肇、新部彩乃、高石官均、日比紀文、河上裕
- Organizer
  第70回日本癌学会
- Place of Presentation
  愛知　名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] Analysis of humanimmune responses using newlydeveloped murine MHC class I andII-deficient NOG mice by humanPBMC inoculation2011
- Author(s)
  Yaguchi T
- Organizer
  3rd International Workshop onHUMANIZED MICE
- Place of Presentation
  Pittsburgh,Pennsylvania USA
- Data Source
  KAKENHI-PROJECT-23791293
[Presentation] 卵巣癌におけるNF-κBシグナルの亢進は、IL-6の産生およびMDSCの誘導により、免疫抑制に関与する2010
- Author(s)
  西尾浩、谷口智憲、岩田卓、桜井敏晴、塚本信夫、工藤千恵、藤田知信、河上裕
- Organizer
  第14回日本がん免疫学会
- Place of Presentation
  KKRホテル熊本
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-21890247
[Presentation] 悪性黒色腫および樹状細胞でのWnt/β-cateninシグナル亢進はがん微小環境での免疫抑制に関与する2010
- Author(s)
  谷口智憲、守井賢二、西尾浩、桜井敏晴、塚本信夫、工藤千恵、藤田知信、河上裕
- Organizer
  第14回日本がん免疫学会
- Place of Presentation
  KKRホテル熊本
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-21890247
[Presentation] MicroRNA-222 is a potential target for developing blood-based biomarker assay and treatment of malignant glioma.2010
- Author(s)
  Ryo Ueda, Li Qian, Tomonori Yaguchi, Nobuyoshi Kosaka, Tomonobu Fujita, Hideho Okada, Takahiro Ochiya, Yutaka Kawakami
- Organizer
  第16回日本遺伝子治療学会
- Place of Presentation
  栃木県総合文化センター
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-21890247
[Presentation] Blockade of activated NF-kB in cancer and immune cells mayeliminate immunosuppressive state in human ovarian cancer2010
- Author(s)
  Hiroshi Nishio, Tomonori Yaguchi, Tomonobu Fujita, Kazuo Umezawa, Takashi Iwata, Takuma Fujii, Hidetoshi Sumimoto, Daisuke Aoki, Yutaka Kawakami
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21890247
[Presentation] Immunosuppression by human cancer cells and its control for effective immunotherapy.2010
- Author(s)
  Yutaka kawakami, Chie Kudo-Saito, Hidetoshi Sumimoto, Nobuo Tsukamoto, Ryo Ueda, Tomonori Yaguchi.
- Organizer
  14thInternational Congress of Immunology 2010
- Place of Presentation
  Kobe International Convention Center
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21890247
[Presentation] シンポジウム2「次世代がん免疫療法の開発に向けた基礎・応用研究「がん免疫逃避機構とその制御」2010
- Author(s)
  河上裕、住本秀敏、工藤千恵、塚本信夫、植田良、梶原知子、川村直,谷口智憲,
- Organizer
  第14回日本がん免疫学会
- Place of Presentation
  KKRホテル熊本
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-21890247
[Presentation] MicroRNA-222 is a potential target for developing blood-based diagnostic methods and treatment of malignant glioma.2010
- Author(s)
  Ryo Ueda, Qian Li, Tomonori Yaguchi, Nobuyoshi Kosaka, Tomonobu Fujita, Hideho Okada, Takahiro Ochiya, Yutaka Kawakami
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21890247
[Presentation] Immune escape of human melanoma via activated Wnt/β-catenin signaling.2010
- Author(s)
  Yaguchi T, Goto Y, Kido K, Mochimaru H, Sakurai T, Tsukamoto N, Kudo-Saito C, Fujita T, Sumimoto H, Kawakami Y.
- Organizer
  14^<th> International Congress of Immunology 2010
- Place of Presentation
  Kobe International Convention Center
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21890247
[Presentation] Immunosuppressions by human cancer cells and their control for effective immunotherapy.2010
- Author(s)
  Yutaka Kawakami, Chie Kudo-saito, Hidetoshi Sumimoto, Nobuo Tsukamoto, Ryo Ueda, Naoshi Kawamura, Tomonori Yaguchi
- Organizer
  第72回日本血液学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21890247
[Presentation] Possible improvement of cancer immunotherapy based on thaanalyses of anti-tumor immune responses in human.2010
- Author(s)
  Yutaka Kawakami, Chie kudo-Saito, Hidetoshi Sumimoto, Ryo Ueda, Nobuo Tsukamoto, Tomonobu Fujita, Toshiharu Sakurai, Tomonori Yaguchi
- Organizer
  金沢国際がん生物学シンポジウム
- Place of Presentation
  KKRホテル金沢
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-21890247
[Presentation] Reversal of cancer induced immunosuppression by targeting altered signaling molecules in cancer cells and immune cells.2010
- Author(s)
  Yutaka Kawakami, Hidetoshi sumimoto, Tomoko Iwata-Kajihara, Tomonori Yaguchi, Naoshi Kawamura, Chie Kudo-Saito, Nobuo Tsukamoto
- Organizer
  14thInternational Congress of Immunology 2010
- Place of Presentation
  Kobe International Convention Center
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21890247
[Presentation] Immune escape of human melanoma via activated Wnt/β-catenin signaling.2010
- Author(s)
  Tomonori Yaguchi, Yasufumi Goto, Kenji Kido, Hiroshi Mochimaru, Toshiharu Sakurai, Nobuo Tsukamoto, Chie Kudo-Saito, Tomonobu Fujita, Hidetoshi Sumimoto, Yutaka Kawakami
- Organizer
  14thInternational Congress of Immunology 2010
- Place of Presentation
  Kobe International Convention Center
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21890247
[Presentation] Increased cell motility and immunosuppression ability of human melanoma via ectopically expressed histatin-12010
- Author(s)
  Tomonori Yaguchi, Tomoki Kurihara, Yasufumi Goto, Yuki Ito, Kenji Morii, Hidetoshi Sumimoto, Yutaka Kawakami
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21890247
[Presentation] MAPK signaling is a potential target for improvement of immunotherapy through reversal of immunosuppressive tumor microenvironment.2009
- Author(s)
  谷口智憲、岩田-梶原知子、川村直、工藤-斉藤千恵、住本秀敏、河上裕
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21890247
[Presentation] EGFR-TKIs (EGFR- tyrosin kinase inhibitors) enhance anti-tumor immune responses by acting on both non-small cell lung carcinoma cells and immune cells
- Author(s)
  Yaguchi T, Satomi R, Kobayashi A, Morii K, Kawakami Y.
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] 分子標的薬併用による効果的な個別化がん免疫療法
- Author(s)
  河上裕、早川妙香、中村謙太、ボリヤナポピバノバ、杉山重里、西尾浩、谷口智憲
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] 悪性黒色腫に異所性に発現するHistatin-1はin vivoで細胞運動能と免疫抑制能を亢進させる
- Author(s)
  谷口智憲
- Organizer
  第16回日本がん免疫学会
- Place of Presentation
  北海道大学学術交流会館（北海道）
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] 局所性Renin-Angiotensin systemの阻害による、がん関連線維芽細胞や骨髄系免疫細胞の制御を介したPD-1/PD-L1免疫チェックポイント阻害療法の効果増強
- Author(s)
  中村謙太、谷口智憲、大村学、小林明日香、川村直、杉山重里、桜井敏晴、木庭幸子、奥山隆平、河上裕
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  松山
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] 高吸収性クルクミン併用による免疫抑制改善効果を介した免疫チェックポイント阻害療法の効果増強
- Author(s)
  早川妙香、杉山重里、今泉厚、谷口智憲、河上裕
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  松山
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] CD155-TIGIT interaction is an immune checkpoint regulating antimelanoma immune responses
- Author(s)
  猪爪隆史、谷口智憲、古田潤平、原田和俊、伊藤守、河上裕、島田眞路
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  松山
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] Effective cancer immunotherapy for human melanoma by combination of BRAF inhibitor and Toll-like receptor 7 agonist
- Author(s)
  Nakamura K, Yaguchi T, Popivanova B, Murata M, Mikoshiba A, Kiniwa Y, Okuyama R, Kawakami Y
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] Enhanced anti-tumor effects of the PD-1/PD-L1 blockade by combining a highly absorptive form of NF-kB/STAT3 inhibitor curcumin
- Author(s)
  Hayakawa T, Sugiyama J, Yaguchi T, Imaizumi A, Kawakami Y.
- Organizer
  Society for Immunotherapy of Cancer 29th Annual Meeting
- Place of Presentation
  National Harbor, MD, USA.
- Year and Date
  2014-11-06 – 2014-11-09
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] ヒト末梢血移入マウスMHC class I/IIノックアウトNOGマウスを用いたヒト腫瘍免疫応答のin vivo解析
- Author(s)
  谷口智憲、小林明日香、片野いくみ、何裕遥、猪爪隆史、伊藤守、河上裕
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  松山
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-25830122
[Presentation] 悪性黒色腫で亢進するWnt/β-cateninシグナルは免疫抑制的で腫瘍を促進する微小環境を誘導する
- Author(s)
  谷口智憲
- Organizer
  第71回日本癌学会
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-23240128
[Presentation] ルクミン併用による免疫抑制改善効果を介した免疫チェックポイント阻害療法の効果増強
- Author(s)
  早川妙香、杉山重里、谷口智憲、今泉厚、河上裕
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25830122

1. KAWAKAMI Yutaka (50161287)

# of Collaborated Projects: 8 results

# of Collaborated Products: 105 results
2. IWATA TAKASHI (30296652)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
3. OHTA Shigeki (20365406)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. Hiroshi Nishio (90445239)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. SAKURAI Toshiharu (20101933)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
6. TSUKAMOTO Nobuo (20407117)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
7. INOZUME Takashi (80334853)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. TAKAHASHI Hayato (40398615)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. Kato Daiki (60843216)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. 臼井達哉 (80727652)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KUDO Chie (90424126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. FUJITA Tomonobu (20199334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
13. AMAGAI Masayuki (90212563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KINIWA Yukiko (20436893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAKAMURA Shoko (20528228)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. KATSUMI Tsukazaki (40118972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NAMIKI Takeshi (50401352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. YOKOZEKI Hiroo (90210608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KATAYAMA Ichiro (80191980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TANEMURA Atsushi (50457016)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. KANEKO Yasuhiko (50373387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. Fukuda Keiichi (20199227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 舩越建 (80365353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
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# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
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# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
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# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 富安博隆 (70776111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 西村亮平 (80172708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
29. 辻本元 (60163804)

# of Collaborated Projects: 1 results

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30. 桃井康行 (40303515)

# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
32. 池田凡子 (60967339)

# of Collaborated Projects: 1 results

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33. 高橋洋介 (50912549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 有田誠 (80292952)

# of Collaborated Projects: 1 results

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35. 福田桂太郎 (60464848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 飯田慶 (00387961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. ITO Ryoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. OGAWA Yoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 榛村重人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 坪田一男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 但馬正樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 柊元巌

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yaguchi Tomonori 谷口 智憲

YAGUCHI Tomonori 谷口 智憲

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Comparative analysis of immunological memory against cancersPrincipal Investigator

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抗腫瘍免疫応答に関与する遺伝子スプライシング機構の解明Principal Investigator

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Analysis of immunosuppression by ER stress in cancer microenvironmentsPrincipal Investigator

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Evaluation of the role of beta-catenin pathway in human melanoma in anti-cancer immune responsesPrincipal Investigator

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Identification of the sub-population in human malignant melanoma showing strong resistance to tumor specific cytotoxic T cellsPrincipal Investigator

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Yaguchi Tomonori 谷口智憲

YAGUCHI Tomonori 谷口智憲