Nakajima Akira 中島晶

… Alternative Names

中島晶ナカジマアキラ

NAKAJIMA Akira 中島晶

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Researcher Number	20419237
Other IDs
Affiliation (Current)	2025: 弘前大学, 農学生命科学部, 教授
Affiliation (based on the past Project Information) *help	2025: 弘前大学, 農学生命科学部, 教授 2022 – 2023: 弘前大学, 農学生命科学部, 教授 2016: 名古屋大学, 医学系研究科, 講師 2014 – 2015: 名古屋大学, 医学(系)研究科(研究院), 講師 2012: 名古屋大学, 医学(系)研究科(研究院), 講師 … More 2012: 名古屋大学, 医学系研究科, 講師 2011: 名古屋大学, 医学(系)研究科(研究院), 特任講師 2010: 名古屋大学, 医学系研究科, 特任講師 2009: Nagoya University, 大学院・医学系研究科, 特任講師 2007 – 2008: Tohoku University, 大学院・薬学研究科, 助教 2005 – 2006: Tohoku University, Graduate School of Pharmaceutical Sciences, Instructor, 大学院・薬学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 64010:Environmental load and risk assessment-related / Applied pharmacology / General pharmacology / Medical pharmacy / Biological pharmacy Except Principal Investigator Biological pharmacy
Keywords	Principal Investigator 臭素系難燃剤 / 内分泌かく乱物質 / 脳神経系 / 難燃剤 / 神経毒性 / セロトニン / ドーパミン / 危険ドラッグ / 合成カチノン / 神経炎症 … More / Toll様受容体 / アストログリア / 統合失調症 / サイトカイン / 神経発達障害 / IFITM3 / 黒室 / in silico / 黒質 / 胆汁酸 / トランスポーター / 構造活性送還 / ノビレチン / 構造活性相関 / 記憶・学習 … More Except Principal Investigator CapZ / V-1 / CNS neurodegeneration / Regeneratin of brain function / Neurogenesis / TH gene / Transcriptional regulation / Actin dynamics / neurosphere / 蛋白質相互作用 / 天然ハーブエキス / 脳神経幹細胞 / 神経再生 / 神経機能制御 / アクチンフィラメント形成 / レトロウイルスベクター / 中枢神経変性疾患 / 脳機能再生 / 神経新生 / TH遺伝子 / 転写制御 / アクチンダイナミックス Less

有機リン系難燃剤が脳神経系に与える影響の検証Principal Investigator
- Principal Investigator
  
  中島晶
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 64010:Environmental load and risk assessment-related
- Research Institution
  Hirosaki University
内分泌かく乱物質である臭素系難燃剤の脳神経系に対する影響の解明Principal Investigator
- Principal Investigator
  
  中島晶
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 64010:Environmental load and risk assessment-related
- Research Institution
  Hirosaki University
Mechanisms by which synthetic cathinones induce neurotoxicityPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Akira
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Nagoya University
Analysis of upstream and downstream signaling of IFITM3Principal Investigator
- Principal Investigator
  
  NAKAJIMA Akira
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Analysis of functional significance of a newly discovered brain-specific transporterPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Akira
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya University
  Tohoku University
生薬成分ノビレチン誘導体の記憶・学習障害改善効果における構造活性相関研究Principal Investigator
- Principal Investigator
  
  中島晶
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Elucidation of physiological significance of a novel regulator of neuronal functions and its application to functional regeneration of brain
- Principal Investigator
  
  YAMAKUNI Tohru
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University

All 2023 2022 2013 2012 2011 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Tetrabromobisphenol A and hexabromocyclododecane, brominated flame retardants, trigger endoplasmic reticulum stress and activate necroptosis signaling in PC12 cells.2023
- Author(s)
  Abe N, Sasaki M, Nakajima A.
- Journal Title
  
  Environ Toxicol Pharmacol.
  
  Volume: 98 Pages: 104056-104056
- DOI
  10.1016/j.etap.2022.104056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K12411
[Journal Article] Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice2013
- Author(s)
  Ibi D, Nagai T, Nakajima A, Mizoguchi H, Kawase T, Tsuboi D, Kano SI, Sato Y, Hayakawa M, Lange UC, Adams DJ, Surani MA, Satoh T, Sawa A, Kaibuchi K, Nabeshima T, Yamada K
- Journal Title
  
  Glia
  
  Volume: 61 Pages: 679-693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790290
[Journal Article] Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice2013
- Author(s)
  D Ibi, I Nagai, A Nakajima, H Mizoguchi, T Kawase, D Tsuboi, S Kano, Y Sato, M Hayakawa, U. C. Lange, D. J. Adams, M. Azim Surani, T Satoh, A Sawa, K Kaibuchi, T Nabeshima and K Yamada
- Journal Title
  
  Glia
  
  Volume: 61 Issue: 5 Pages: 679-693
- DOI
  10.1002/glia.22461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PROJECT-20227006, KAKENHI-PROJECT-22390046, KAKENHI-PROJECT-23591594, KAKENHI-PROJECT-23790290, KAKENHI-PROJECT-23791220, KAKENHI-PUBLICLY-24111518, KAKENHI-PROJECT-24657140
[Journal Article] Neurobehavioral effects of tetrabromobisphenol A, a brominated flame retardant, in mice2009
- Author(s)
  Nakajima A, Saigusa D, Tetsu N, Yamakuni T, Tomioka Y, Hishinuma T
- Journal Title
  
  Toxicol Lett
  
  Volume: 189 Pages: 78-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390044
[Journal Article] Neurobehavioral effects of tetrabromobisphenol A, a brominated flame retardant, in mice2009
- Author(s)
  Akira Nakajima, et al.
- Journal Title
  
  Toxicol Lett 189
  
  Pages: 78-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390044
[Journal Article] Nobiletin, a citrus flavonoid that improves memory impairment, rescues bulbectomy-induced cholinergic neurodegeneration in mice.2007
- Author(s)
  Nakajima A, Yamakuni T, Haraguchi M, Omae N, Song SY, Kato C, Nakagawasai O, Tadano T, Yokosuka A, Mimaki Y, Sashida Y, Ohizumi Y.
- Journal Title
  
  J. Pharmacol. Sci. 105
  
  Pages: 122-126
- NAID
  10024316002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790040
[Journal Article] Nobiletin, a citrus flavonoid, reverses learning impairment associated with NMDA receptor antagonism by activation of ERK signaling.2007
- Author(s)
  Nakajima A, Yamakuni T, Matsuzaki K, Nakata N, Onozuka H, Yokosuka A, Sashida Y, Mimaki Y, Ohizumi Y.
- Journal Title
  
  J. Pharmacol. Exp. Ther. 321
  
  Pages: 784-790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790040
[Presentation] RNA-seq解析を用いた臭素系難燃剤であるテトラブロモビスフェノールA とヘキサブロモシクロドデカンによる神経毒性発現メカニズムの検討2023
- Author(s)
  中島晶、佐々木麻音、阿部ななみ
- Organizer
  第５０回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-22K12411
[Presentation] 臭素系難燃剤であるテトラブロモビスフェノールAとヘキサブロモシクロドデカンはPC12細胞においてネクロトーシスシグナルを活性化する2022
- Author(s)
  中島晶、阿部ななみ
- Organizer
  第４９回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-22K12411
[Presentation] 培養アストログリア細胞における Toll 様受容体刺激は神経発達障害関連膜タンパク質IFITM3 の発現を誘導する2012
- Author(s)
  中島晶ら
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790290
[Presentation] 神経発達障害に関連する膜タンパク質IFITM3のTLRリガンドによる発現誘導2011
- Author(s)
  中島晶ら
- Organizer
  第41回日本神経精神薬理学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790290
[Presentation] 生薬成分ノビレチンはアミロイド前駆体蛋白質(APP)トランスジェニックマウスの記憶障害およびアミロイド沈着を改善する2008
- Author(s)
  中島晶、小野塚寛、松崎健太郎、辛龍雲、萩野晃一、北本哲也、横須賀章人、指田豊、三巻祥浩、大泉康、山國徹
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18790040
[Presentation] 神経発達障害に関連する膜タンパク質IFITM3のTLRリガンドによる発現誘導
- Author(s)
  中島晶、衣斐大祐、永井拓、鍋島俊隆、山田清文
- Organizer
  第４１回日本神経精神薬理学会
- Place of Presentation
  東京（京王プラザホテル）
- Data Source
  KAKENHI-PROJECT-23790290
[Presentation] 培養アストログリア細胞におけるToll様受容体刺激は神経発達障害関連膜タンパク質IFITM3の発現を誘導する
- Author(s)
  中島晶、衣斐大祐、永井拓、鍋島俊隆、山田清文
- Organizer
  第８５回日本薬理学会年会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-23790290

1. MANO Nariyasu (50323035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. TOMIOKA Yoshihisa (00282062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. YAMAGUCHI Hiroaki (80400373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. YAMAKUNI Tohru (30333793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OHIZUMI Yasushi (00006355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAITO Shin-ya (80271849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 織田進吾 (10725534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 李玉山 (50344685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Nakajima Akira 中島 晶

中島 晶 ナカジマ アキラ

NAKAJIMA Akira 中島 晶

Research Projects

Research Products

Co-Researchers

有機リン系難燃剤が脳神経系に与える影響の検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

内分泌かく乱物質である臭素系難燃剤の脳神経系に対する影響の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms by which synthetic cathinones induce neurotoxicityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of upstream and downstream signaling of IFITM3Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of functional significance of a newly discovered brain-specific transporterPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

生薬成分ノビレチン誘導体の記憶・学習障害改善効果における構造活性相関研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of physiological significance of a novel regulator of neuronal functions and its application to functional regeneration of brain

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Tetrabromobisphenol A and hexabromocyclododecane, brominated flame retardants, trigger endoplasmic reticulum stress and activate necroptosis signaling in PC12 cells.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice2013

Author(s)

Journal Title

Data Source

[Journal Article] Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neurobehavioral effects of tetrabromobisphenol A, a brominated flame retardant, in mice2009

Author(s)

Journal Title

Data Source

[Journal Article] Neurobehavioral effects of tetrabromobisphenol A, a brominated flame retardant, in mice2009

Author(s)

Journal Title

Data Source

[Journal Article] Nobiletin, a citrus flavonoid that improves memory impairment, rescues bulbectomy-induced cholinergic neurodegeneration in mice.2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Nobiletin, a citrus flavonoid, reverses learning impairment associated with NMDA receptor antagonism by activation of ERK signaling.2007

Author(s)

Journal Title

Data Source

[Presentation] RNA-seq解析を用いた臭素系難燃剤であるテトラブロモビスフェノールA とヘキサブロモシクロドデカンによる神経毒性発現メカニズムの検討2023

Nakajima Akira 中島晶

中島晶ナカジマアキラ

NAKAJIMA Akira 中島晶