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Yamaoka Kunihiro  山岡 邦宏

… Alternative Names

YAMAOKA Kunihiro  山岡 邦宏

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Researcher Number 20425317
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-8858-9435
Affiliation (Current) 2025: 北里大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 北里大学, 医学部, 教授
2010 – 2011: 産業医科大学, 医学部, 講師
2007 – 2009: University of Occupational and Environmental Health, Japan, School of Medicine, assistant professor
2006: 産業医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 54020:Connective tissue disease and allergy-related / 膠原病・アレルギー・感染症内科学
Except Principal Investigator
膠原病・アレルギー・感染症内科学
Keywords
Principal Investigator
単球 / MS4A4A / 関節リウマチ / 樹状細胞 / マクロファージ / 破骨細胞 / MS4A4A単球 / フローサイトメトリー / ノックアウトマウス / 末梢血 … More / 滑膜細胞 / 単球系細胞 / 共刺激分子 / Jak阻害剤 / Jak3 / 滑膜線維芽細胞 / 骨代謝 / サイトカイン / リウマチ学 / Stat5 / 自己免疫疾患 / Stat6 / 臨床免疫学 … More
Except Principal Investigator
transcriptional regulation / transcriptional factor / inflammatory cytokine / IL1 beta / 遺伝子発現調節 / 転写因子 / 炎症性サイトカイン / IL-1β Less
  • Research Projects

    (6 results)
  • Research Products

    (141 results)
  • Co-Researchers

    (10 People)
  •  自然免疫細胞に発現するMS4A4Aの自己免疫疾患病態との関連と臨床応用Principal Investigator

    • Principal Investigator
      山岡 邦宏
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Kitasato University
  •  Elucidation of MS4A4A function in rheumatoid arthritis pathogenesis and establishment of basic information for new treatment methodsPrincipal Investigator

    • Principal Investigator
      Yamaoka Kunihiro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Kitasato University
  •  Function and clinical application of MS4A4A involved in pathology of rheumatoid arthritisPrincipal Investigator

    • Principal Investigator
      Yamaoka Kunihiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Kitasato University
  •  Development of novel medication strategy and drug efficacy on monocyte lineage cells of a JAK3 inhibitor in rheumatoid arthritis patientsPrincipal Investigator

    • Principal Investigator
      YAMAOKA Kunihiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Function of Stat5 in myeloid lineage cells : A explorative research to control autoimmune diseasePrincipal Investigator

    • Principal Investigator
      YAMAOKA Kunihiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Therapeutic strategy for inflammatory diseases by a novel negative regulatory transcriptional factor of inflammatory cytokines

    • Principal Investigator
      SAITO Kazuyoshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      University of Occupational and Environmental Health, Japan

All 2023 2022 2021 2012 2011 2010 2009 Other

All Journal Article Presentation Book

  • [Book] 関節リウマチ治療 実践バイブル 改訂第2版2021

    • Author(s)
      山岡 邦宏
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Book] 関節リウマチ治療 実践バイブル 改訂第2版2021

    • Author(s)
      有沼 良幸, 山岡 邦宏
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Book] 関節リウマチ薬はこう使う!2021

    • Author(s)
      山岡 邦宏
    • Publisher
      月刊薬事 じほう
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Book] 今日の治療指針2022年版2021

    • Author(s)
      山岡 邦宏
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Book] 内科学2021

    • Author(s)
      山岡 邦宏
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Book] ファーマナビゲーター,リウマチ~生物学的製剤編単独投与、抗リウマチ薬(MTX)の併用との使い分けのコツありますか2010

    • Author(s)
      山岡邦宏, 田中良哉
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Sustained remission following the discontinuation of tofacitinib in patients with rheumatoid arthritis (XANADU study): an open-label randomised study.2023

    • Author(s)
      Kubo S., Miyazaki Y., Amano K., Matsui K., Kameda H., Inoue Y., Nakayamada S., Ogura T., Kaneko Y., Yamaoka K., Tanaka Y
    • Journal Title

      RMD Open

      Volume: 9(2) Issue: 2 Pages: e003029-e003029

    • DOI

      10.1136/rmdopen-2023-003029

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Journal Article] Rituximab in the real-world treatment of lupus nephritis: A retrospective cohort study in Japan2023

    • Author(s)
      Tanaka Y., Nakayamada S., Yamaoka K., Ohmura K., Yasuda S.
    • Journal Title

      Modern Rheumatol

      Volume: 33(1) Issue: 1 Pages: 211-153

    • DOI

      10.1093/mr/roac007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Journal Article] JAK inhibitors in rheumatology2023

    • Author(s)
      Yamaoka Kunihiro、Oku Kenji
    • Journal Title

      Immunological Medicine

      Volume: online ahead Issue: 3 Pages: 1-10

    • DOI

      10.1080/25785826.2023.2172808

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08792, KAKENHI-PROJECT-21K08446
  • [Journal Article] MACE and VTE across upadacitinib clinical trial programmes in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis2023

    • Author(s)
      Charles‐Schoeman C., Choy E., McInnes IB., Mysler E., Nash P., Yamaoka K., Lippe R., Khan N., Shmagel, AK., Palac H., Suboticki J., Curtis JR.
    • Journal Title

      RMD Open

      Volume: 9(4) Issue: 4 Pages: e003392-e003392

    • DOI

      10.1136/rmdopen-2023-003392

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Journal Article] Investigation of the poor prognostic factors for life and functional prognosis in patients with asymptomatic dermatomyositis2023

    • Author(s)
      Kondo J, Oku K., Hasegwa Y., Muramatsu T., Matsueda Y., Arinuma Y., Yamaoka K.
    • Journal Title

      Kitasato Med J.

      Volume: 53 Pages: 21-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Journal Article] Safety profile of upadacitinib in patients at risk of cardiovascular disease: integrated post hoc analysis of the SELECT phase III rheumatoid arthritis clinical programme2023

    • Author(s)
      Fleischmann R., Curtis JR., Schoeman CC., Mysler E., Yamaoka K., Richez C., Palac H., Dilley D., Liu J., Strengholt S
    • Journal Title

      Ann Rheum Dis

      Volume: 82(9) Issue: 9 Pages: 1130-1141

    • DOI

      10.1136/ard-2023-223916

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Journal Article] Real-world efficacy of belimumab in achieving remission or low-disease activity in systemic lupus erythematosus: A retrospective study2023

    • Author(s)
      Hasegawa Y., Arinuma Y., Asakura H., Shindo R., Ino K., Kanayama Y., Tanaka T., Matsueda Y., Wada T., Oku K., Yamaoka K.
    • Journal Title

      Mod Rheumatol.

      Volume: - Issue: 4 Pages: 732-740

    • DOI

      10.1093/mr/road078

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08446, KAKENHI-PROJECT-20K17449
  • [Journal Article] Efficacy and safety of single-dose ivermectin in mild-to-moderate COVID-19: the double-blind, randomized, placebo-controlled CORVETTE-01 trial2023

    • Author(s)
      Wada t., Hibino M., Yamaoka K,.et al.
    • Journal Title

      Front Med (Lausanne)

      Volume: 10:1139046

    • DOI

      10.3389/fmed.2023.1139046

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Journal Article] Varied risk of developing herpes zoster among molecular targeting therapy in rheumatoid arthritis patients: a single-center study.2023

    • Author(s)
      Muramatsu T., Oku K., Ikenoue T., Kondo J., Hasegawa Y., Matsueda Y., Arinuma Y., Yamaoka, K
    • Journal Title

      Kitasato Med J

      Volume: 53 Pages: 10-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Journal Article] The pathogenic role of lupus-specific autoantibodies and Interleukin-6 on demyelination of the brainstem and spinal cord in systemic lupus erythematosus2023

    • Author(s)
      Hasegawa Yasuhiro、Arinuma Yoshiyuki、Muramatsu Takumi、Kondou Junichi、Matsueda Yu、Kanayama Yoshiro、Ino Kazuma、Tanaka Tomoki、Wada Tatsuhiko、Oku Kenji、Yamaoka Kunihiro
    • Journal Title

      Lupus

      Volume: 32 Issue: 3 Pages: 401-410

    • DOI

      10.1177/09612033231151600

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08792, KAKENHI-PROJECT-21K08446, KAKENHI-PROJECT-20K17449
  • [Journal Article] Malignancy risk with tofacitinib versus TNF inhibitors in rheumatoid arthritis: results from the open-label, randomised controlled ORAL Surveillance trial2023

    • Author(s)
      Curtis JR., Yamaoka K., Chen Y-H., Bhatt DL., Gunay LM., Sugiyama N., Connell CA., Wang C., Wu J., Menon S., Vranic I.,
    • Journal Title

      Ann Rheum Dis

      Volume: 82(3) Issue: 3 Pages: 331-343

    • DOI

      10.1136/ard-2022-222543

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Journal Article] Japan College of Rheumatology guidance for the use of methotrexate in patients with rheumatoid arthritis: Secondary publication2023

    • Author(s)
      Kameda H., Yamaoka K., Yamanishi Y., Tada M., Koike R., Nakajima A., Fusama M., Fujii T
    • Journal Title

      Mod Rheumatol .

      Volume: 34(1) Issue: 1 Pages: 1-10

    • DOI

      10.1093/mr/road098

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Journal Article] Involvement of the complement system in immune thrombocytopenia: review of the literature2023

    • Author(s)
      Shindo R., Abe R., Oku K., Tanaka T., Matsueda., Wada T., Arinuma Y., Tanaka S., Ikenoue T., Miyakawa Y., Yamaoka K
    • Journal Title

      Immunol Med

      Volume: 46(4) Issue: 4 Pages: 182-190

    • DOI

      10.1080/25785826.2023.2213976

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08446, KAKENHI-PROJECT-20K17449
  • [Journal Article] Correlation between soluble TREM2 and anti-GluN2 antibody in lupus patients with diffuse psychiatric and neuropsychological syndromes2022

    • Author(s)
      Arinuma Yoshiyuki、Hasegawa Yasuhiro、Tanaka Tomoki、Matsueda Yu、Wada Tatsuhiko、Oku Kenji、Yamaoka Kunihiro
    • Journal Title

      Rheumatology

      Volume: 62 Issue: 4 Pages: e105-e106

    • DOI

      10.1093/rheumatology/keac488

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08792, KAKENHI-PROJECT-21K08446
  • [Journal Article] Clinical and immunological effects of hydroxychloroquine in patients with active rheumatoid arthritis despite antirheumatic treatment2022

    • Author(s)
      Takei H, Takanashi S, Otomo K, Hanaoka H, Kikuchi J, Yamaoka K, Yoshimoto K, Abe T, Takeuchi T, Kaneko Y.
    • Journal Title

      Mod Rheumatol.

      Volume: - Issue: 1 Pages: 50-59

    • DOI

      10.1093/mr/roac153

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K16350, KAKENHI-PROJECT-22K08527, KAKENHI-PROJECT-21K08446, KAKENHI-PROJECT-21K18227
  • [Journal Article] Safety and efficacy of filgotinib for Japanese patients with RA and inadequate response to MTX: FINCH 1 52-week results and FINCH 4 48-week results2022

    • Author(s)
      Tanaka Yoshiya、Matsubara Tsukasa、Tsutomu Takeuchi, et al.
    • Journal Title

      Modern Rheumatology

      Volume: ー Issue: 4 Pages: 668-679

    • DOI

      10.1093/mr/roac084

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03720, KAKENHI-PROJECT-21K08446
  • [Journal Article] Integrated safety analysis of filgotinib treatment for rheumatoid arthritis in patients from Japan over a median of 1.5 years2022

    • Author(s)
      Ishiguro Naoki、Tanaka Yoshiya、Matsubara Tsukasa、Atsumi Tatsuya、Amano Koichi、Sugiyama Eiji、Yamaoka Kunihiro、Winthrop Kevin、Kivitz Alan、Burmester Gerd R、Gottenberg Jacques-Eric、Genovese Mark C、Matzkies Franziska、Guo Ying、Jiang Deyuan、Takeuchi Tsutomu
    • Journal Title

      Modern Rheumatology

      Volume: 33 Issue: 1 Pages: 64-72

    • DOI

      10.1093/mr/roac020

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03720, KAKENHI-PROJECT-21K08446
  • [Journal Article] Incidence and risk factors for herpes zoster in patients with rheumatoid arthritis receiving upadacitinib: a pooled analysis of six phase III clinical trials.2022

    • Author(s)
      Winthrop KL., Nash P., Yamaoka K., Mysler E., Khan N., Camp K L., Song Y., Suboticki J L., Curtis J R .
    • Journal Title

      Annals of the Rheumatic Diseases

      Volume: 81(2): Issue: 2 Pages: 206-213

    • DOI

      10.1136/annrheumdis-2021-220822

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Journal Article] Clinical management of herpes zoster in patients with rheumatoid arthritis and psoriatic arthritis receiving tofacitinib treatment.2022

    • Author(s)
      Winthrop KL., Curtis JR., Yamaoka K., Lee EB. ,Hirose T., Rivas JL., Kwok K., Burmester GR.
    • Journal Title

      Rheumatology and Therapy

      Volume: 9(1) Issue: 1 Pages: 243-263

    • DOI

      10.1007/s40744-021-00390-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Journal Article] Long-term safety and efficacy of filgotinib treatment for rheumatoid arthritis in Japanese patients naive to MTX treatment (FINCH 3)2022

    • Author(s)
      Atsumi Tatsuya、Tanaka Yoshiya、Matsubara Tsukasa、Amano Koichi、Ishiguro Naoki、Sugiyama Eiji、Yamaoka Kunihiro、Westhovens Ren、Ching Daniel W T、Messina Osvaldo Daniel、Burmester Gerd R、Genovese Mark、Bartok Beatrix、Pechonkina Alena、Kondo Akira、Yin Zhaoyu、Gong Qi、Tasset Chantal、Takeuchi Tsutomu
    • Journal Title

      Modern Rheumatology

      Volume: ー Issue: 4 Pages: 657-667

    • DOI

      10.1093/mr/roac083

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03720, KAKENHI-PROJECT-21K08446
  • [Journal Article] Serum cytokines and bone metabolic markers in patients with rheumatoid arthritis treated with biological disease modifying anti-rheumatic drugs2022

    • Author(s)
      Tamai Hiroya、Nishina Naoshi、Kikuchi Jun、Izumi Keisuke、Otomo Kotaro、Yoshimoto Keiko、Yamaoka Kunihiro、Takeuchi Tsutomu、Kaneko Yuko
    • Journal Title

      Clinical Rheumatology

      Volume: 42 Issue: 3 Pages: 721-730

    • DOI

      10.1007/s10067-022-06390-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03720, KAKENHI-PROJECT-21K08446
  • [Journal Article] Efficacy and safety of upadacitinib over 84 weeks in Japanese patients with rheumatoid arthritis (SELECT-SUNRISE).2021

    • Author(s)
      Kameda H, Takeuchi T, Yamaoka K, Oribe M, Kawano M, Yokoyama M, Pangan A, Konishi Y, Meerwein S,Tanaka Y.
    • Journal Title

      Arthritis Research & Therapy

      Volume: 23(1):9 Issue: 1 Pages: 1-10

    • DOI

      10.1186/s13075-020-02387-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Journal Article] Thymus variants on imaging in patients with rheumatoid arthritis-Clinical and immunological significance.2021

    • Author(s)
      Murata O., Suzuki K., Takeuchi T., Sugiura H., Kondo Y., Takeshita M., Koga K., Takiguchi M., Kassai Y., Yasuoka H., Yamaoka K., Morita R., Yoshimura A.
    • Journal Title

      Rheumatology(Oxford)

      Volume: 60(12) Issue: 12 Pages: 5595-5600

    • DOI

      10.1093/rheumatology/keab164

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Journal Article] A Case of Anti-MDA5 Antibody-positive Dermatomyositis Developing Reversible Cerebral Vasospasm Syndrome Successfully Treated by Multi-Immunosuppressant Combination Including Mycophenolate Mofetil.2021

    • Author(s)
      Muramatsu T, Tono T, Kanayama Y, Hasegawa Y, Kondo J, Hoshiyama T, Wada T, Arinuma Y, Tanaka S, Yamaoka K.
    • Journal Title

      Modern Rheumatology Case Reports

      Volume: 5 (1) Issue: 1 Pages: 69-75

    • DOI

      10.1080/24725625.2020.1810398

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Journal Article] Janus kinase (JAK)阻害薬tofacitinibの作用機序と自己免疫疾患治療薬への可能性2012

    • Author(s)
      山岡邦宏、田中良哉
    • Journal Title

      リウマチ科

      Volume: 47 Pages: 97-100

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Anti-rheumatic effect of JAK inhibitors2012

    • Author(s)
      Yamaoka K., Maeshima K., Kubo S., Sonomoto K., Tanaka Y.
    • Journal Title

      Jpn J Clin.Immunol

      Volume: 35 Pages: 112-117

    • NAID

      10030573749

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Effect of COX-2 selective inhibitor celecoxib on upper gastrointestinal symptoms in patients with rheumatoid arthritis-Evaluation of switch from non-steroidal anti-inflammatory drugs2012

    • Author(s)
      Hirata S., Saito K., Sawamukai N., Nakano K., Yamaoka K., Tanaka Y.
    • Journal Title

      Kyushu J Rheumatol

      Volume: 32 Pages: 17-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] JAK-Statシグナル伝達経路を介したIL-10の産生制御2012

    • Author(s)
      山岡邦宏、田中良哉
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 57 Pages: 470-474

    • NAID

      40019309840

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Churg-Strauss syndrome complicated by bilateral central retinal artery occlusion2012

    • Author(s)
      Katsuyama T., Saito K., Yamaoka K, Hirata S., Tsujimura S., Nawata M., Tanaka Y.
    • Journal Title

      Kyushu J Rheumatol

      Volume: 32 Pages: 52-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] JAK阻害薬2012

    • Author(s)
      山岡邦宏、田中良哉
    • Journal Title

      医薬ジャーナル

      Volume: (In press)

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Mesenchymal stem cells : A new treatment tool for rheumatoid arthritis2012

    • Author(s)
      Sonomoto K., Yamaoka K., Tanaka Y.
    • Journal Title

      Inflammation and Regeneration Journal

      Volume: (In press)

    • NAID

      130004482298

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Regulation of inflammation through JAK3-Stat6 pathway in dendritic cells2012

    • Author(s)
      Yamaoka K, Maeshima K, Kubo S, Tanaka Y
    • Journal Title

      Jpn J Clin Immunol

      Volume: 35 Pages: 62-68

    • NAID

      10030465675

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] In vitro and in vivo analysis of a Jak inhibitor in rheumatoid arthritis2012

    • Author(s)
      Tanaka Y, Maeshima K, Yamaoka K
    • Journal Title

      Ann Rheum Dis

      Volume: 71(Supp II)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] JAK3の発見から臨床応用まで2012

    • Author(s)
      山岡邦宏、田中良哉
    • Journal Title

      炎症と免疫

      Volume: 20 Pages: 268-271

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] JAK阻害薬tofacitinibの抗リウマチ作用2012

    • Author(s)
      山岡邦宏、田中良哉
    • Journal Title

      医学のあゆみ

      Volume: 240 Pages: 562-566

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] ヒトB細胞活性化におけるSykを介したTLR9シグナルの増幅メカニズム2012

    • Author(s)
      岩田慈、山岡邦宏、新納宏昭、赤司浩一、田中良哉
    • Journal Title

      臨床免疫・アレルギー科

      Volume: (In press)

    • NAID

      130006947788

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Involvement of Syk in pathology of systemic autoimmune disease2012

    • Author(s)
      Iwata S, Yamaoka K, Tanaka Y
    • Journal Title

      Jpn J Clin Immunol

      Volume: 35 Pages: 56-61

    • NAID

      10030465649

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Amplification of toll-like receptor-mediated signaling through Syk in human B cell activation2012

    • Author(s)
      Iwata S, Yamaoka K, Tanaka Y
    • Journal Title

      J Allergy and Clinical Immunology

    • NAID

      40019337340

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] 樹状細胞におけるJAK3-Stat6を介した炎症制御機構2012

    • Author(s)
      山岡邦宏、久保智史、前島圭佑、田中良哉
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 57 Pages: 264-268

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] ヒト間葉系幹細胞による破骨細胞の活性制御2012

    • Author(s)
      尾下浩一、山岡邦宏、田中良哉
    • Journal Title

      リウマチ科

      Volume: (In press)

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] JAK阻害薬の有用性は?2012

    • Author(s)
      前島圭佑、山岡邦宏、石井宏治、田中良哉
    • Journal Title

      内科

      Volume: 109 Pages: 664-666

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Anti-rheumatic effect of JAK inhibitors2012

    • Author(s)
      Yamaoka K, Maeshima K, Kubo S, Sonomoto K, Tanaka Y
    • Journal Title

      Jpn J Clin. Immunol

    • NAID

      10030573749

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Marked improvement of calcinosis in adult dermatomyositis with etidronate therapy2012

    • Author(s)
      Mori H., Okada Y., Yamaoka K., Tanaka Y.
    • Journal Title

      J Bone Miner Metab

      Volume: 30 Pages: 114-118

    • NAID

      10031168760

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] JAK inhibitor : tofacitinib, a new disease modifying anti-rheumatic drug2011

    • Author(s)
      Yamaoka K, Kubo S, Sonomoto K, Maeshima K, Tanaka Y
    • Journal Title

      Inflammation and Regeneration Journal

      Volume: 31 Pages: 349-353

    • NAID

      130004482280

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] In vitro and in vivo analysis of a Jak inhibitor in rheumatoid arthritis2011

    • Author(s)
      Tanaka Y., Maeshima K., Yamaoka K.
    • Journal Title

      Ann Rheum Dis

      Volume: 71

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Phenotypic Changes of Lymphocytes in Patients with Systemic Lupus Erythematosus who are in the long-term remission After B Cell Depletion Therapy with Rituximab2011

    • Author(s)
      Iwata S, Yamaoka K, Tanaka Y
    • Journal Title

      J Rheumatol

      Volume: 38 Pages: 633-641

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Jak and Syk : Emerging their relevance to the treatment of inflammatory diseases2011

    • Author(s)
      Tanaka Y, Iwata S, Yamaoka K
    • Journal Title

      Inflammation and Regeneration Journal

      Volume: 31 Pages: 237-44

    • NAID

      130004943791

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Human mesenchymal stem cells inhibit osteoclastogenesis through osteoprotegerin production2011

    • Author(s)
      Oshita K, Yamaoka K, Tanaka Y
    • Journal Title

      Arthritis Rheum

      Volume: 63 Pages: 1658-1667

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Janus kinase(JAK) inhibitors in rheumatoid arthritis2011

    • Author(s)
      Yamaoka K, Tanaka Y
    • Journal Title

      Curr Rheum Rev

      Volume: 7 Pages: 306-312

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Janus kinase (JAK)特異的阻害薬の効果に基づく作用機序の検討2011

    • Author(s)
      山岡邦宏、田中良哉
    • Journal Title

      リウマチ科

      Volume: 46 Pages: 84-88

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Pericarditis induced by prophylactic administration of isoniazid in a patient with rheumatoid arthritis2011

    • Author(s)
      Kubo S, Yamaoka K, Saito K, Tanaka Y
    • Journal Title

      Joint Bone spine

      Volume: 78 Pages: 99-100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Efficacy of combination therapy of anti-TNF-α antibody infliximab and methotrexate in refractory entero-Behcet's disease2011

    • Author(s)
      Iwata S, Yamaoka K, Tanaka Y
    • Journal Title

      Mod Rheumatol

      Volume: 21 Pages: 184-191

    • NAID

      10029361883

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Human mesenchymal stem cells inhibit osteoclastogenesis through osteoprotegerin production.2011

    • Author(s)
      Oshita K., Yamaoka K., et al.
    • Journal Title

      Arthritis Rheumatol.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Janus kinase (JAK) inhibitors in rheumatoid arthritis2011

    • Author(s)
      Yamaoka K., Tanaka Y.
    • Journal Title

      Curr Rheum Rev

      Volume: 7 Pages: 306-312

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Cytokine-mediated signals as targets for treatment of rheumatoid arthritis : a JAK inhibitor in vitro and in vivo2011

    • Author(s)
      Tanaka Y, Yamaoka K
    • Journal Title

      Int J Clin Rheumatol

      Volume: 6 Pages: 439-4444

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Dopamine induces IL-6-dependent IL-17 production via D1-like receptor on CD4 naive T-cells and a D1-like receptor antagonist SCH-23390 inhibits cartilage destruction in a human rheumatoid arthritis/SCID mouse chimera model2011

    • Author(s)
      Nakano K, Yamaoka K, Tanaka Y
    • Journal Title

      J Immunol

      Volume: 186 Pages: 3745-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Dopamine induces IL-6-dependent IL-17 production via D1-like receptor on CD4 naive T-ceIts and a Dl-like receptor antagonist SCH-23390 inhibits cartilage destruction in a human rheumatoid arthritis/SCID mouse chimera model.2011

    • Author(s)
      Nakano K, Yamaoka K., et al.
    • Journal Title

      J Immunol

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] 細胞内シグナル分子を標的とした治療:JAK2011

    • Author(s)
      山岡邦宏、田中良哉
    • Journal Title

      最新医学

      Volume: in press

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] A JAK inhibitor tofacitinib regulates synovitis through inhibition of IFN-・and IL-17 production by human CD4+T cells2011

    • Author(s)
      Maeshima K, Yamaoka K, Tanaka Y
    • Journal Title

      Arthritis Rheum

      Volume: (In press) Issue: 6 Pages: 1790-1798

    • DOI

      10.1002/art.34329

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Involvement of mast cells in systemic sclerosis2010

    • Author(s)
      Yukawa S, Yamaoka K, Tanaka Y
    • Journal Title

      Jpn. J. Clin. Immunol

      Volume: 33 Pages: 81-86

    • NAID

      10027753435

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] C5a promotes migration, proliferation, and vessel-formation in endothelial cells2010

    • Author(s)
      Kurihara R, Yamaoka K, Tanaka Y
    • Journal Title

      Inflamm Res

      Volume: 59 Pages: 659-666

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] シグナル伝達分子を標的とした関節リウマチ治療:新規抗リウマチ薬の可能性2009

    • Author(s)
      山岡邦宏、田中良哉
    • Journal Title

      医学のあゆみ 230

      Pages: 786-791

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Jak阻害の特異性と関節リウマチに対する治療効果2009

    • Author(s)
      山岡邦宏、田中良哉
    • Journal Title

      感染・炎症・免疫 39

      Pages: 63-65

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Jak inhibitor ; possibility and mechanism as a new disease modifying anti-rheumatic drug2009

    • Author(s)
      Yamaoka K, Tanaka Y
    • Journal Title

      Jpn J Clin Immunol

      Volume: 32 Pages: 85-91

    • NAID

      10024962052

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Jak3阻害2009

    • Author(s)
      山岡邦宏、田中良哉
    • Journal Title

      炎症と免疫 17

      Pages: 524-529

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] RAにおけるチロシンキナーゼ阻害薬の役割2009

    • Author(s)
      山岡邦宏、田中良哉
    • Journal Title

      Frontiers in Rheuma& Clinlmmunol 3

      Pages: 32-36

    • NAID

      40017004423

    • Data Source
      KAKENHI-PROJECT-21591275
  • [Journal Article] Amplification of toll-like receptor-mediated signaling through Syk in human B cell activation

    • Author(s)
      Iwata S., Yamaoka K, Niiro H., Nakano K., Wang SP., Akashi K., Tanaka Y.
    • Journal Title

      J Allergy and Clinical Immunology

      Volume: (In press)

    • NAID

      40019337340

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] 最新エビデンスから紐解く関節リウマチ治療~JAK阻害薬のベネフィット・リスク~2023

    • Author(s)
      山岡 邦宏
    • Organizer
      第8回日本骨免疫学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] 膠原病に伴う慢性血栓塞栓性肺高血圧症の臨床的特徴の検討.2023

    • Author(s)
      下手 公介、松枝 佑、次田 奈央、池田 慶介、岩楯 洋祐、朝倉 啓友、田中 知樹、和田 達彦、有沼 良幸、奥 健志、田中 住明、山岡 邦宏.
    • Organizer
      第67回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] 分子標的治療薬を用いたD2TRA治療2023

    • Author(s)
      山岡 邦宏
    • Organizer
      第67回日本リウマチ学会総会・学術集会 シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] 帯状疱疹ワクチンの既存情報からリウマチ膠原病患者での接種方法を考える2023

    • Author(s)
      山岡 邦宏
    • Organizer
      第38回日本臨床リウマチ学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] 関節リウマチの骨破壊病態に対する分子標的治療薬の作用と臨床的効果2023

    • Author(s)
      山岡 邦宏
    • Organizer
      第7回日本骨免疫学会冬期学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] Decreased peripheral monocyte and neutrophil count associate with drug persistency in rheumatoid arthritis patients treated with a Janus kinase inhibitor.2023

    • Author(s)
      Shishido E,. Matsueda Y,. Yamaoka K.et al
    • Organizer
      25rd The Asia Pacific League of Associations for Rheumatology(APLAR)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] expression in peripheral blood monocytes of patients with rheumatoid arthritis.2023

    • Author(s)
      村松匠、奥 健志、松枝 佑、近藤 惇一、長谷川 靖浩、山岡 邦宏.
    • Organizer
      第67回日本リウマチ学会
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] MS4A4A expression in peripheral blood monocytes of patients with rheumatoid arthritis.2023

    • Author(s)
      Muramatsu T, Oku K, Matsueda Y, Kondo J, Hasegawa Y, Yamaoka K.
    • Organizer
      第67回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] 当院における膠原病疾患合併間質性肺疾患(CTD-ILD)に対するnintedanib治療の実際.2023

    • Author(s)
      池田 慶介、田中 知樹、次田 奈央、岩楯 洋祐、朝倉 啓友、下手 公介、松枝 佑、有沼 良幸、和田 達彦、奥 健志、田中 住明、山岡 邦宏
    • Organizer
      第67回日本リウマチ学会総会・学術集会.
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] JAK阻害第一次無効により他のb/tsDMARDへスイッチを行った関節リウマチ患者尾予後.2023

    • Author(s)
      尾方 優香、村松 匠、有沼 良幸、奥 健志、山岡 邦宏
    • Organizer
      第67回日本リウマチ学会総会・学術集会.
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] Finding the right treatment for the right patient: what similarities and key differences among RA, PsA and axSpA determine treatment decisions,2023

    • Author(s)
      Yamaoka K
    • Organizer
      European congress of Pheumatology(EULAR 2023)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] 抗Sm抗体はMMP-2を介してClaudin-5の分解を促進しカプトプリルにより回復する2023

    • Author(s)
      有沼 良幸、奥 健志、山岡 邦宏
    • Organizer
      第51回日本臨床免疫学会総会
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] べリムマブ投与後に不安症状を呈した全身性エリテマトーデスの1例における髄液IL-6と抗MMDA受容体サブユニットGluN2抗体の変化2023

    • Author(s)
      有沼 良幸、奥 健志、山岡 邦宏.
    • Organizer
      第51回日本臨床免疫学会総会
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] csDMARDで効果不十分な日本人関節リウマチ(RA) 患者におけるウパダシニブ(UPA)の有効性及び安全性:SELECT-SUNRISE試験5年間の結果.2023

    • Author(s)
      亀田 秀人、竹内 勤、山岡 邦宏、織部 元廣、川野 光弘、横山 雅行、小西 裕子、長南 寿実、Penn SK, Camp HS、 田中 良哉.
    • Organizer
      第67回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] MTX皮下注射製剤を含めたMTXの用法・用量2023

    • Author(s)
      山岡 邦宏
    • Organizer
      第67回日本リウマチ学会総会・学術集会 シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] べリムマブ投与後に不安症状を呈した全身性エリテマトーデスの1例における髄液IL-6と抗NMDA受容体サブユニットGluN2抗体の変化.2023

    • Author(s)
      有沼 良幸、下出 公介、進藤 理沙、長谷川 靖浩、田中 知樹、松枝 佑、和田 達彦、奥 健志、山岡 邦宏.
    • Organizer
      第67回日本リウマチ学会総会・学術集会.
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] 関節リウマチ治療におけるtsDMARDsの課題に向けた取り組み2023

    • Author(s)
      山岡 邦宏
    • Organizer
      第38回日本臨床リウマチ学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] 関節リウマチに対する分子標的治療の安全性と課題.2023

    • Author(s)
      山岡 邦宏
    • Organizer
      第31回日本医学会総会学術集会
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] 分子の基礎的解析から治療薬へ、そしてその先へ2023

    • Author(s)
      山岡 邦宏
    • Organizer
      日本臨床免疫学会・第4回免疫疾患横断セミナー
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] Non-HIV ニューモシスチス肺炎(PCP)に続発した慢性呼吸窮迫症候群(ARDS)対しトシリズマブ(TCZ)が有効であった関節リウマチ(RA)の一例.2023

    • Author(s)
      次田 奈央、和田 達彦、池田 慶介、岩楯 洋祐、朝倉 啓友、下手 公介、田中 知樹、松枝 佑、有沼 良幸、奥 健志、田中 住明、山岡 邦宏.
    • Organizer
      第67回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] 関節リウマチ患者に対する生物学的製剤導入クリニカルパス入院の患者満足度調査結果と感染症による入院の予防効果の検証.2023

    • Author(s)
      中村 絵美里、井下 千葉美、西川 美紀、東野 俊洋、田中 知樹、山岡 邦宏.
    • Organizer
      第67回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] ANCA関連血管炎の寛解維持におけるリツキシマブ治療の効果.2023

    • Author(s)
      岩楯 洋祐、奥 健志、池田 慶介、木下 奈々、京田 俊介、阪本 陽介、宍戸 瑛理、朝倉 啓友、田中 知樹、松枝 佑、和田 達彦、有沼 良幸、田中 住明、山岡 邦宏.
    • Organizer
      第67回日本リウマチ学会総会・学術集会.
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] Effect of Belimumab on Patient-Reported Outcomes in patients with systemic lupus erythematosus.2023

    • Author(s)
      Hasegawa Y, Arinuma Y, Oku K, Yamaoka K.
    • Organizer
      第67回日本リウマチ学会総会・学術集会.
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] 日本人関節リウマチ患者におけるヒドロキシクロロキンの有効性、安全性の検討.2023

    • Author(s)
      武井 裕史、高梨 敏史、大友 耕太郎、花岡 洋成、菊池 潤、山岡 邦宏、吉本 桂子、竹内 勤、金子 祐子.
    • Organizer
      第67回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] 初発全身性エリテマトーデス患者におけるヒドロキシクロロキン単剤療法の有効性と関連する臨床的因子の検討.2023

    • Author(s)
      田中 宏昌、長谷川 靖浩、有沼 良幸、奥 健志、山岡 邦宏.
    • Organizer
      第67回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] Investigation of poor prognostic factors in patients with asymptomatic dermatomyositis2023

    • Author(s)
      Kondo J, Oku K, Matseda Y, Hasegawa Y, Muramatsu T, Kanayama Y, Ino K, Shindo R, Arinuma Y, Yamaoka K.
    • Organizer
      第67回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] Two-Year Outcome of Belimumab Therapy in Patients with Systemic Lupus Erythematosus.2023

    • Author(s)
      AsakuraH, Hasegawa Y, Arinuma Y, Tsugita N, Ikeda K, Iwadate Y, Shimode K, Tanaka T, Matsueda Y, Wada T, Tanaka S, Oku K, Yamaoka K.
    • Organizer
      第67回日本リウマチ学会総会・学術集会.
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] Treatment goals, targets and guidelines in lupus nephritis2021

    • Author(s)
      Yamaoka K
    • Organizer
      23nd Asia-Pacific League of Associations for Rhuematology Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] JAKと生物製剤による関節破壊治療の最前線  Front-line treatments forthe joint destructive disease; JAK inhibitors andbiologics2021

    • Author(s)
      山岡 邦宏.
    • Organizer
      第42回炎症・再生医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] Considering the efficacy of tofacitinibthrough recent information on safety.2021

    • Author(s)
      Yamaoka K
    • Organizer
      23nd Asia-Pacific League of Associations for Rhuematology Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] 関節リウマチの新規治療2021

    • Author(s)
      山岡 邦宏
    • Organizer
      第36回 日本臨床リウマチ学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] 乾癬性関節炎患者におけるウパダシニブの安全性:全体集団及び日本人集団における臨床試験併合解析の結果(Safety Profile of Upadacitinib in Psoriatic Arthritis (PsA): Findings in the Global Population and Japanese Subgroup From a Pooled Analysis of 2 Phase 3 Clinical Trials.)2021

    • Author(s)
      Yamaoka K., Burmester GR., Winthrop K., Nash P. Goupille P., Azevedo VF., Salvarani C., Mccaskill RM., Liu J, Pierre-Louis BJ., Anderson JK., Ruderman EM.
    • Organizer
      第65回日本リウマチ学会総会・学術集会.
    • Data Source
      KAKENHI-PROJECT-21K08446
  • [Presentation] JAK-Statシグナル伝達経路阻害による抗炎症作用2011

    • Author(s)
      山岡邦宏、田中良哉
    • Organizer
      第29回日本骨代謝学会
    • Place of Presentation
      大阪国際会議場(大阪)(招待講演)
    • Year and Date
      2011-07-28
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] 次世代低分子化合物を用いた治療-JAK阻害薬2011

    • Author(s)
      山岡邦宏
    • Organizer
      第55回日本リウマチ学会総会Next decadeシンポジウム
    • Place of Presentation
      神戸ポートピアホテル(神戸)
    • Year and Date
      2011-07-19
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] JAK-STATシグナル伝達経路阻害による炎症抑制作用2011

    • Author(s)
      山岡邦宏、前島圭佑、久保智史、園本格士郎、湯川宗之助、岩田慈、田中伸哉、宮原寿明、田中良哉
    • Organizer
      第32回日本炎症再生医学会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2011-06-03
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] A JAK inhibitor, tofacitinib reduces IL-6 and matrix metalloproteinase-3 production in rheumatoid arthritis with suppressed cartilage destruction2011

    • Author(s)
      Yamaoka K., Kubo S., Sonomoto K., Maeshima K., Tanaka Y.
    • Organizer
      1st Bio-Rheumatology International Congress
    • Place of Presentation
      ヒルトン東京ベイホテル(東京)
    • Year and Date
      2011-11-15
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] IL-10 production induced by LPS is negatively regulated by Stat6 in dendritic cells2011

    • Author(s)
      Yamaoka K
    • Organizer
      第40回日本免疫学会学術集会
    • Place of Presentation
      幕張メッセ(千葉)
    • Year and Date
      2011-11-27
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] リウマチ性疾患の治療の進歩-低分子化合物の可能性と作用機序2011

    • Author(s)
      山岡邦宏、田中良哉
    • Organizer
      第39回日本臨床免疫学会総会
    • Place of Presentation
      京王プラザホテル(東京)(招待講演)
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] JAK-Statシグナル伝達経路阻害による抗炎症作用2011

    • Author(s)
      山岡邦宏
    • Organizer
      第29回日本骨代謝学会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2011-07-28
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] JAK-STATシグナル伝達経路阻害による炎症抑制作用2011

    • Author(s)
      山岡邦宏
    • Organizer
      第32回日本炎症再生医学会
    • Place of Presentation
      第32回日本炎症再生医学会京都国際会館(京都)
    • Year and Date
      2011-06-03
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] リウマチ性疾患の治療の進歩-低分子化合物の可能性と作用機序2011

    • Author(s)
      山岡邦宏
    • Organizer
      合同シンポジウム1第39回日本臨床免疫学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] JAK阻害薬による関節リウマチ治療とその作用機序2011

    • Author(s)
      山岡邦宏
    • Organizer
      第39回日本臨床免疫学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] 次世代低分子化合物を用いた治療-JAK阻害薬2011

    • Author(s)
      山岡邦宏、田中良哉
    • Organizer
      第55回日本リウマチ学会総会学術集会
    • Place of Presentation
      神戸ポートピアホテル(神戸)(招待講演)
    • Year and Date
      2011-07-19
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Tofacitinib reduces Interleukin-6 and Matrix Metalloproteinase-3 production and inhibits cartilage destruction in rheumatoid arthritis2011

    • Author(s)
      Yamaoka K., Kubo S., Maeshima K., Sonomoto K., Nakano K., Sawamukai N., Iwata S., Nawata M., Saito K., Tanaka Y.
    • Organizer
      American college of Rheumatology
    • Place of Presentation
      McCormick Place West(シカゴ)
    • Year and Date
      2011-11-06
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] JAK阻害薬投与による関節リウマチ患者由来CD4+T細胞のIL-17産生抑制作用2011

    • Author(s)
      山岡邦宏
    • Organizer
      第55回日本リウマチ学会総会学術集会
    • Place of Presentation
      神戸ポートピアホテル(神戸)
    • Year and Date
      2011-07-19
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] 低分子化合物を用いた治療の進歩2011

    • Author(s)
      山岡邦宏
    • Organizer
      シンポジウム19;関節リウマチの診療の革新的進歩第61回日本アレルギー学会秋季学術大会
    • Place of Presentation
      グランドプリンスホテル新高輪(東京)
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Tofacitinib reduces Interleukin-6 and Matrix Metalloproteinase-3 production and inhibits cartilage destruction in rheumatoid arthritis2011

    • Author(s)
      Yamaoka K
    • Organizer
      American college of Rheumatology McCormick Place West
    • Place of Presentation
      シカゴ
    • Year and Date
      2011-11-06
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] 樹状細胞Stat6のIL-10産生制御機構2011

    • Author(s)
      山岡邦宏
    • Organizer
      第39回日本臨床免疫学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] 低分子化合物を用いた治療の進歩2011

    • Author(s)
      山岡邦宏、田中良哉
    • Organizer
      第61回日本アレルギー学会秋季学術大会
    • Place of Presentation
      グランドプリンスホテル新高輪(東京)(招待講演)
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Stat6 in dendritic cells is involved in inflammation by negatively regulating IL-10 production2010

    • Author(s)
      Yamaoka K
    • Organizer
      第14回国際免疫学会
    • Place of Presentation
      神戸ポートピアホテル(神戸)
    • Year and Date
      2010-08-24
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Jak阻害薬の抗リウマチ薬としての可能性とその作用機序2010

    • Author(s)
      山岡邦宏
    • Organizer
      第75回日本インターフェロンサイトカイン学会
    • Place of Presentation
      北九州国際会議場(北九州)
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] JAKインヒビター2010

    • Author(s)
      山岡邦宏
    • Organizer
      第31回日本炎症再生医学会
    • Place of Presentation
      シンポジウム京王プラザホテル(東京)
    • Year and Date
      2010-08-06
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Jak阻害薬(CP-690, 550)による臨床的効果とMMP-3低下作用2010

    • Author(s)
      山岡邦宏
    • Organizer
      第54回日本リウマチ学会総会学術集会
    • Place of Presentation
      神戸ポートピアホテル(神戸)
    • Year and Date
      2010-04-23
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Involvement of Stat6 in inflammation by negatively regulating IL-10production2010

    • Author(s)
      Yamaoka K
    • Organizer
      第11回欧州リウマチ学会
    • Place of Presentation
      Fiera di Roma(ローマ)
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] 樹状細胞のJak3-Stat6によるIL-10産生制御を介した炎症性疾患制御2010

    • Author(s)
      山岡邦宏
    • Organizer
      第54回日本リウマチ学会総会学術集会
    • Place of Presentation
      神戸(神戸ポートピアホテル)
    • Year and Date
      2010-04-22
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Jak阻害薬の抗リウマチ薬としての可能性とその作用機序2010

    • Author(s)
      山岡邦宏
    • Organizer
      第54回日本リウマチ学会総会学術集会
    • Place of Presentation
      神戸ポートピアホテル(神戸)
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] 樹状細胞のJak3-Stat6によるIL-10産生制御を介した炎症性疾患制御2010

    • Author(s)
      山岡邦宏
    • Organizer
      第54回日本リウマチ学会総会学術集会
    • Place of Presentation
      神戸ポートピアホテル(神戸)
    • Year and Date
      2010-04-22
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] JAK-STATシグナル伝達経路阻害による炎症抑制作用2010

    • Author(s)
      山岡邦宏
    • Organizer
      第75回日本インターフェロンサイトカイン学会
    • Place of Presentation
      北九州国際会議場(北九州)
    • Year and Date
      2010-06-25
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Role of Jak3-Stat6 and effect of Jak inhibitor on dendritic cells and itsinvolvement in rheumatoid arthritis2009

    • Author(s)
      山岡邦宏, 他
    • Organizer
      日本臨床免疫学会
    • Place of Presentation
      東京(東京ステーションコンファレンス)
    • Year and Date
      2009-11-14
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] 関節リウマチに対するJak阻害剤の樹状細胞を介した効果2009

    • Author(s)
      山岡邦宏
    • Organizer
      第53回日本リウマチ学会総会学術集会
    • Place of Presentation
      グランドプリンスホテル新高輪(東京)
    • Year and Date
      2009-04-26
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Role of Jak3-Stat6 in dendritic cells and its involvement in inflammation2009

    • Author(s)
      山岡邦宏, 他
    • Organizer
      日本免疫学会
    • Place of Presentation
      大阪(大阪国際会議場)
    • Year and Date
      2009-12-04
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Inhibition of Jak3-Stat6 pathway leading to an anti-inflammatory process in rheumatoid arthritis2009

    • Author(s)
      山岡邦宏, 他
    • Organizer
      アメリカリウマチ学会
    • Place of Presentation
      フィラデルフィア、USA(Pennsylvania Convention Center)
    • Year and Date
      2009-10-19
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Role of Jak3-Stat6 and effect of Jak inhibitor on dendritic cells and its involvement in rheumatoid arthritis2009

    • Author(s)
      Yamaoka K
    • Organizer
      第37回日本臨床免疫学会
    • Place of Presentation
      東京ステーションコンファレンス(東京)
    • Year and Date
      2009-11-14
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Role of Jak3-Stat6 in dendritic cells and its involvement in inflammation2009

    • Author(s)
      Yamaoka K
    • Organizer
      第39回日本免疫学会総会学術集会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] 関節リウマチに対するJak阻害剤の樹状細胞を介した効果2009

    • Author(s)
      山岡邦宏, 他
    • Organizer
      日本リウマチ学会
    • Place of Presentation
      東京(グランドプリンスホテル新高輪)
    • Year and Date
      2009-04-24
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Jak3-Stat6 in dendritic cells ; involvement in the pathological condition of RA2009

    • Author(s)
      Yamaoka K
    • Organizer
      第74回日本インターフェロンサイトカイン学会
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2009-06-27
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Jak3-Stat6 in dendritic cells ; involvement in the pathological condition of RA2009

    • Author(s)
      山岡 邦宏, 他
    • Organizer
      日本インターフェロン・サイトカイン学会
    • Place of Presentation
      京都(日芝蘭会館)
    • Year and Date
      2009-06-27
    • Data Source
      KAKENHI-PROJECT-21591275
  • [Presentation] Inhibition of Jak3-Stat6 pathway leading to an anti-inflammatory process in rheumatoid arthritis2009

    • Author(s)
      Yamaoka K
    • Organizer
      American college of Rheumatology Pennsylvania convention center
    • Place of Presentation
      フィラデルフィア
    • Year and Date
      2009-10-18
    • Data Source
      KAKENHI-PROJECT-21591275
  • 1.  TANAKA Yoshiya (30248562)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 49 results
  • 2.  松枝 佑 (00623208)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 3.  SAITO Kazuyoshi (30279327)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  竹内 勤 (50179610)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 5.  吉本 桂子 (20383292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  有沼 良幸 (30527437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 18 results
  • 7.  奥 健志 (70544295)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  高梨 敏史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  近藤 泰
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  金子 祐子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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