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Mayanagi Taira  真柳 平

… Alternative Names

MAYANAGI Taira  真柳 平

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Researcher Number 20432544
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-7984-186X
Affiliation (Current) 2025: 岩手医科大学, 医歯薬総合研究所, 講師
Affiliation (based on the past Project Information) *help 2018 – 2024: 岩手医科大学, 医歯薬総合研究所, 講師
2015 – 2017: 岩手医科大学, 医学部, 講師
2013: 岩手医科大学, 医歯薬総合研究所, 講師
2010: 大阪大学, 連合小児発達学研究科, 特任助教(常勤)
2009: 大阪大学, 医学系研究科, 特任助教
2007 – 2009: Osaka University, Graduate School of Medicine, Specially Appointed Assistant Professor
2006: 子どものこころの分子統御機構研究センター, 特任助手(常勤)
Review Section/Research Field
Principal Investigator
Basic Section 52030:Psychiatry-related / Basic Section 46010:Neuroscience-general-related / Basic / Social brain science / Neuroscience in general
Except Principal Investigator
Basic Section 51030:Pathophysiologic neuroscience-related / Natural medicines / General physiology / Neurochemistry/Neuropharmacology / Plastic surgery
Keywords
Principal Investigator
シナプス / PSD-Zip70 / DNAメチル化 / ヒストンアセチル化 / HDAC8 / エピゲノム制御 / 幼少期ストレス / リン酸化制御 / 脱リン酸化 / 局在変化 … More / シナプス応答 / グルタミン酸 / リン酸化・脱リン酸化 / タンパク質局在変化 / シナプス可塑性 / トランスジェニックマウス / 脳機能 / ストレス / Rap2 / 不安 / prefrontal cortex / 動物モデル / ノックアウトマウス / 行動解析 / 発達障害 / 前頭前皮質 / PSD / スパイン / シグナル伝達 / 脳・神経 … More
Except Principal Investigator
シナプス / 周産期・幼少期ストレス / 発達障害 / 幼少期ストレス / エピジェネティクス / バイオマーカー / DNAメチル化 / 微生物由来ガン抑制因子 / ガン抑制遺伝子 / 細胞性粘菌 / ガン抑制因子 / G protein-coupled receptor(GPCR) / LPA receptor / vascular smooth muscle cell / atherosclerosis / dopamine receptor / postsvnantic density(PSD) / synapse / structure biology / 膜ターゲッティング / X線構造解析 / G蛋白質共役型受容体 / X線構造解 / 可塑性 / フーリエ変換 / 神経前駆細胞 / PSD-Zip45 / 膜蛋白質クラスター / ミリスチン酸化 / G蛋白質共役型受容体(GPCR) / 膜ターゲティング / LPAレセプター / 膜クラスター / PSD蛋白質 / ドーパミンD1レセプター / GPCR / 膜貫通型受容体 / G蛋白質共役受容体(GPCR) / LPA受容体 / 血管平滑筋細胞 / 動脈硬化症 / ドーパミン受容体 / シナプス後肥厚部(PSD) / 構造生物学 / 二重還流装置 / インサート / MI細胞 / イオンチャネル / 集合管 / 腎尿細管 / チャネル局在 / チャネル活性 / 膜発現 / パッチクランプ法 / 細胞膜極性 / 腎集合管細胞 / チャネル発現 / 遺伝子導入 / 腎集合管 / 管腔膜 / M-1細胞 / 遺伝子発現 / 膜蛋白質遺伝子発現 / Kチャネル / ROMK / 神経回路網 / カルデスモン / 大脳皮質形成 / 内分泌恒常性 / 甲状腺ホルモン / 内分泌 / シナプス形成障害 / 大脳形成障害 / ストレス / グルココルチコイド / 感情障害 Less
  • Research Projects

    (10 results)
  • Research Products

    (33 results)
  • Co-Researchers

    (22 People)
  •  HDAC8-mediated epigenomic regulation by early life stressPrincipal Investigator

    • Principal Investigator
      真柳 平
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Iwate Medical University
  •  Establishment of Biomarkers for Intellectual and Mental Developmental Delays in Children Due to Stress Exposure During the Perinatal Period

    • Principal Investigator
      Sobue Kenji
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Iwate Medical University
  •  Regulation of synapse plasticity by stimulation-dependent dephosphorylation and translocation of PSD-Zip70Principal Investigator

    • Principal Investigator
      Mayanagi Taira
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 46010:Neuroscience-general-related
    • Research Institution
      Iwate Medical University
  •  ケロイド・肥厚性瘢痕の形成メカニズムの解明と治療法の開発

    • Principal Investigator
      柏 克彦
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Iwate Medical University
  •  Analysis of mechanism of a novel cancersuressor derived from microorganism

    • Principal Investigator
      KUWAYAMA Hidekazu
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Natural medicines
    • Research Institution
      University of Tsukuba
  •  Validation of PSD-Zip70 knockout mice as a novel mouse model for neurodevelopmental disorder.Principal Investigator

    • Principal Investigator
      Mayanagi Taira
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Basic / Social brain science
    • Research Institution
      Iwate Medical University
  •  Molecular mechanisms for expression of renal potassium channels in doubly-perfused cultured collecting duct cells.

    • Principal Investigator
      KUBOKAWA Manabu
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Iwate Medical University
  •  PSD‐Zip70によるシナプス形成・可塑性の動的制御Principal Investigator

    • Principal Investigator
      真柳 平
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neuroscience in general
    • Research Institution
      Osaka University
  •  Study for the molecular basis of affective disorders caused by the dysregulated homeostasis of endocrine system

    • Principal Investigator
      SOBUE Kenji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka University
  •  Establishment of a novel analysis system for three-dimentional structure of transmembrane receptors based on neuronal and vascular cell plasticity

    • Principal Investigator
      SOBUE Kenji
    • Project Period (FY)
      2003 – 2007
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Osaka University

All 2020 2019 2018 2017 2016 2015 2014 2013 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book

  • [Book] 生物学辞典2010

    • Author(s)
      真柳平、祖父江憲治(共著), 石川統、黒岩常祥、塩見正衛、松本忠夫、守隆夫、八杉貞夫、松本正幸編集
    • Publisher
      東京化学同人
    • Data Source
      KAKENHI-PROJECT-21700352
  • [Journal Article] Social Stress-Induced Postsynaptic Hyporesponsiveness in Glutamatergic Synapses Is Mediated by PSD-Zip70-Rap2 Pathway and Relates to Anxiety-Like Behaviors2020

    • Author(s)
      Taira Mayanagi, Kenji Sobue
    • Journal Title

      Frontiers in Cellular Neuroscience

      Volume: 13 Pages: 564-564

    • DOI

      10.3389/fncel.2019.00564

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06466
  • [Journal Article] Kensuke Asakura, Taira Mayanagi, Shingo Kimura, Tamotsu Sugai, Takayuki Matsumoto, Kenji Sobue.2019

    • Author(s)
      Kensuke Asakura, Taira Mayanagi, Shingo Kimura, Tamotsu Sugai, Takayuki Matsumoto, Kenji Sobue.
    • Journal Title

      岩手医学雑誌

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06466
  • [Journal Article] Myocardin-related transcription factor A (MRTF-A) regulates TGF-β2-induced type I collagen production in human lens epithelial cells.2018

    • Author(s)
      Takashi Okuno , Toshiyasu Imaizumi, Umi Sakamoto, Daisuke Sakai, Kazuhiro Fukuda, Atsushi Sanbe, Taira Mayanagi, Kenji Sobue, Daijiro Kurosaka.
    • Journal Title

      岩手医学雑誌

      Volume: 70 Pages: 81-90

    • NAID

      130007473038

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06466
  • [Journal Article] Na+/H+ exchange regulatory factor 1 is required for ROMK1 K+ channel expression in the surface membrane of cultured M-1 cortical collecting duct cells.2017

    • Author(s)
      Takashi Suzuki, Kazuyoshi Nakamura, Taira Mayanagi, Kenji Sobue, Manabu Kubokawa.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 489 (2) Issue: 2 Pages: 116-122

    • DOI

      10.1016/j.bbrc.2017.05.104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K21319
  • [Journal Article] Docosahexaenoic Acid Promotes Axon Outgrowth by Translational Regulation of Tau and Collapsin Response Mediator Protein 2 Expression.2016

    • Author(s)
      Toshinari Mita* Taira Mayanagi*, Hiroshi Ichijo, Kentaro Fukumoto, Kotaro Otsuka, Akio Sakai, Kenji Sobue. (* equal contribution)
    • Journal Title

      Journal of Biological Chemistry

      Volume: 291 Issue: 10 Pages: 4955-4965

    • DOI

      10.1074/jbc.m115.693499

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K21319
  • [Journal Article] Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity.2016

    • Author(s)
      Kishi Takayuki, Mayanagi Taira, Iwabuchi Sadahiro, Akasaka Toshihide, Sobue Kenji.
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 44 Pages: 72113-72130

    • DOI

      10.18632/oncotarget.12350

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K21319
  • [Journal Article] SD-Zip70-deficiency causes prefrontal hypofunction associated with glutamatergic synapse maturation defects by dysregulation of Rap2 activity.2015

    • Author(s)
      Taira Mayanagi, Hiroki Yasuda, and Kenji Sobue
    • Journal Title

      Journal of Neuroscience

      Volume: 35 Issue: 42 Pages: 14327-14340

    • DOI

      10.1523/jneurosci.2349-15.2015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26430003, KAKENHI-PROJECT-15K21319
  • [Journal Article] Diversification of caldesmon-linked actin cytoskeleton in cell motility.2011

    • Author(s)
      Mayanagi T., Sobue K.(共著)
    • Journal Title

      Cell Adhesion and Migration

      Volume: 5 Pages: 150-159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21700352
  • [Journal Article] Diversification of caldesmon-linked actin cytoskeleton in cell motility.2011

    • Author(s)
      Mayanagi T, Sobue K.
    • Journal Title

      Cell Adh.Migr

      Volume: 5 Pages: 150-159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240038
  • [Journal Article] Diversification of caldesmon-linked actin cytoskeleton in cell motility.2011

    • Author(s)
      Mayanagi T, Sobue K
    • Journal Title

      Cell Adh.Migr. 5(2)

      Pages: 150-159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240038
  • [Journal Article] Detrimental effects of glucocorticoids on neuronal miglation during brain development.2009

    • Author(s)
      Fukumoto K, Morita T, Mayanagi T, Tanokashira D, Yoshida T, Sakai A, Sobue K
    • Journal Title

      Mol.Psychiatry 14(12)

      Pages: 1119-1131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240038
  • [Journal Article] Detrimental effects of glucocorticoids on neuronal migration during brain development.2009

    • Author(s)
      Fukumoto K, Morita T, Mayanagi T, Tanokashira D, Yoshida T, Sakai A, Sobue K.
    • Journal Title

      Molecular Psychiatry 14

      Pages: 1119-1131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21700352
  • [Journal Article] Glucocorticoid receptor-mediated expression of caldesmon regulates cell migration via the reorganization of the actin cytoskeleton.2008

    • Author(s)
      Mayanagi T., et al.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 31183-31196

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240038
  • [Journal Article] Glucocorticoid receptor-mediated expression of caldesmon regulates cell migration via the reorganization of the actin cytoskeleton.2008

    • Author(s)
      Mayanagi T, Morita T, Hayashi K, Fukumoto K, Sobue K
    • Journal Title

      J.Biol.Chem. 283(45)

      Pages: 31183-31196

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240038
  • [Presentation] Involvement of Rap2-mediated prefrontal dysfunction in social stress-induced anxiety.2018

    • Author(s)
      真柳 平、祖父江 憲治
    • Organizer
      第41回 日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-18K06466
  • [Presentation] 消化管平滑筋におけるh-Caldesmonの生理的役割の解明2018

    • Author(s)
      朝倉謙輔 、真柳平、木村眞吾、菅井有、祖父江憲治、松本主之
    • Organizer
      第56回小腸学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K06466
  • [Presentation] ストレス起因性の不安におけるRap2活性化を伴う前頭前皮質の機能低下の関与2018

    • Author(s)
      真柳 平、祖父江 憲治
    • Organizer
      日本生化学会東北支部第84回例会 (矢巾)
    • Data Source
      KAKENHI-PROJECT-15K21319
  • [Presentation] Involvement of Rap2-mediated prefrontal dysfunction in social stress-induced anxiety.2018

    • Author(s)
      Taira Mayanagi, Kenji Sobue
    • Organizer
      第41回日本神経科学大会 (神戸)
    • Data Source
      KAKENHI-PROJECT-15K21319
  • [Presentation] Possible role of h-caldesmon in the pathogenesis of gastrointestinal motility disorders2018

    • Author(s)
      Kensuke Asakura, Taira Mayanagi, Shingo Kimura, Tamotsu Sugai, Kenji Sobue, Takayuki Matsumoto
    • Organizer
      GI Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06466
  • [Presentation] ストレス起因性の不安におけるRap2活性化を伴う前頭前皮質の機能低下の関与2018

    • Author(s)
      真柳 平、祖父江 憲治
    • Organizer
      日本生化学会 東北支部 第84回 例会
    • Data Source
      KAKENHI-PROJECT-18K06466
  • [Presentation] Characteristics of exogenous expression of ROMK K channels with EGFP fused to the different terminus in polarized and non-polarized membranes in cultured M-1 cells2014

    • Author(s)
      Kubokawa M, Nakamura K, Mayanagi T, Sobue K
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-23590264
  • [Presentation] Expression of exogenously transfected ROMK K^+ channel activity favors the polarized apical membrane of cultured M-1 collecting duct cells2013

    • Author(s)
      Kubokawa M, Nakamura K, Mayanagi T, Sobue K
    • Organizer
      37th International Conference of Physiological Sciences (IUPS)
    • Place of Presentation
      Birmingham, UK
    • Data Source
      KAKENHI-PROJECT-23590264
  • [Presentation] Functional expression of transfected ROMK potassium channels in polarized and non-polarized membranes of cultured M1 cells2013

    • Author(s)
      Kubokawa M, Nakamura K, Mayanagi T, Sobue K
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590264
  • [Presentation] 培養M1集合管細胞へのROMK遺伝子導入によるチャネル活性発現と細胞膜極性との関連2013

    • Author(s)
      久保川学, 中村一芳, 真柳平, 祖父江憲司
    • Organizer
      第56回日本腎臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590264
  • [Presentation] 新皮質発生時におけるグルココルチコイド誘発性のカルデスモン亢進による神経細胞移動の障害2009

    • Author(s)
      福本健太郎、森田強、真柳平、田之頭大輔、吉田智之、酒井明夫、祖父江憲治
    • Organizer
      第61回日本細胞生物学会大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20240038
  • [Presentation] グルココルチコイドによるカルデスモンの発現上昇を介した大脳皮質形成障害2009

    • Author(s)
      福本健太郎、森田強、真柳平、田之頭大輔、吉田智之、酒井明夫、祖父江憲治
    • Organizer
      第61回 日本細胞生物学会大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-06-02
    • Data Source
      KAKENHI-PROJECT-21700352
  • [Presentation] グルココルチコイドによるカルデスモンの発現上昇を介した大脳皮質形成障害2009

    • Author(s)
      福本健太郎、森田強、真柳平、田之頭大輔、吉田智之、酒井明夫、祖父江憲治
    • Organizer
      第32回 日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-09-17
    • Data Source
      KAKENHI-PROJECT-21700352
  • [Presentation] グルココルチコイドによるカルデスモンの発現上昇を介した大脳皮質形成障害2009

    • Author(s)
      福本健太郎、森田強、真柳平、田之頭大輔、吉田智之、酒井明夫、祖父江憲治
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20240038
  • [Presentation] 脳皮質形成のメカニズム 神経化学からの貢献グルココルチコイドにより誘導される神経細胞移動障害の分子メカニズム2008

    • Author(s)
      祖父江憲治、福本健太郎、真柳平
    • Organizer
      第51回日本神経化学日本神経化学会大会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-20240038
  • [Presentation] グルココルチコイドによるCaldesmonの発現誘導を介した細胞形態・運動の制御2007

    • Author(s)
      真柳 平, 他
    • Organizer
      第30回日本分子生物学会・第80回日本生化学会合同大会
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15GS0312
  • [Presentation] Glucocorticoid regulates cell morphology and motiolity via caldesmon induction.2007

    • Author(s)
      Mayanagi, T., et. al.
    • Organizer
      The 30th Annual Meeting of the Molecular Biology Society of Japan, The 80th Annual Meeting of the Japanese Biochemical Society.
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15GS0312
  • [Presentation] 培養M1集合管細胞へのROMK遺伝子導入によるチャネル活性発現と細胞膜極性との関連

    • Author(s)
      久保川 学、中村一芳、真柳 平、祖父江憲司
    • Organizer
      第56回日本腎臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590264
  • 1.  SOBUE Kenji (20112047)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 19 results
  • 2.  HAYASHI Ken'ichiro (90238105)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  MORITA Tsuyoshi (80403195)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 4.  FUKUMOTO Kentar (00514407)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 5.  木村 眞吾 (30214878)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 6.  KUBOKAWA Manabu (70153327)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 7.  NAKAMURA Kazuyoshi (50237385)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 8.  INUI Makoto (70223237)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KUWAYAMA Hidekazu (40397659)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  MAEDA Yasuo (50025417)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  CHIDA Junji (20437651)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  柏 克彦 (70169423)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  小林 誠一郎 (00295966)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  那須 和佳子 (80282177)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  柴田 克志 (70296565)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  今野 大治郎 (00362715)
    # of Collaborated Projects: 1 results
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  • 17.  八木 淳子 (80636035)
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  • 18.  清水 厚志 (30327655)
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  • 19.  赤坂 真奈美 (00405797)
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  • 20.  大桃 秀樹 (90453406)
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  • 21.  小巻 翔平 (90789629)
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  • 22.  安田 浩樹
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