Yamane Masaomi 山根正修

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YAMANE Masaomi 山根正修

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Researcher Number	20432643
Other IDs
Affiliation (Current)	2025: 島根大学, 学術研究院医学・看護学系, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 島根大学, 学術研究院医学・看護学系, 教授 2019 – 2023: 岡山大学, 医歯薬学総合研究科, 准教授 2014: 岡山大学, 医学部附属病院, 助教 2013 – 2014: 岡山大学, 大学病院, 助教 2012: 岡山大学, 医学部附属病院, 助教 … More 2011: 岡山大学, 大学病院, 助教 2009 – 2011: Okayama University, 岡山大学病院, 助教 2010: 岡山大学, 医学部歯学部附属病院, 助教 2009: 岡山大学, 医学部・歯学部付属病院, 助教 2009: 岡山大学, 大学病院, 助教 2009: Okayama University, 病院, 助教 2009: 岡山大学, 腫瘍・胸部外科, 助教 2007 – 2008: Okayama University, Okayama University Hospital, Research Associates 2006: 岡山大学, 医学部・歯学部附属病院, 助手 2006: 岡山大学, 医学部歯学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Thoracic surgery / Basic Section 55040:Respiratory surgery-related Except Principal Investigator Thoracic surgery / Basic Section 55040:Respiratory surgery-related / General surgery / Immunology
Keywords	Principal Investigator 肺移植 / 虚血再灌流障害 / 急性拒絶 / Egr-1 / 虚血再還流障害 / 急性肺障害 / サイトカイン / 核酸医薬 / Spred２ / 虚血再灌流 … More / 肺障害 / SPRED2 / MAPキナーゼ / spred2 / 移植免疫 / マウス肺移植モデル / 急性拒絶反応 / EGR-1 / マウス肺移植 / Egr-l / 転写因子 … More Except Principal Investigator 肺移植 / 虚血再灌流障害 / 心停止ドナー / 温虚血 / 急性拒絶反応 / HMGB1 / HMGB１ / S100 / 抗S100A8/A9中和抗体 / S100A9 / S100A8 / Heparin / Cardiac massage / Urokinese / Non-heart-beating donor / Lung transplantation / ヘパリン / 心マッサージ / ウロキナーゼ / 心臓死ドナー / γδ細胞 / 制御性T細胞 / ヒト / 移植免疫 / アポトーシス / 閉塞性細気管支炎 / 慢性拒絶反応 / ex-vivo evaluation / 再灌流 / Ex-vivo evaluation / 抗ドナー抗体 / 非侵襲的診断法 / 生体肺移植 / 抗ドナー特異的抗体価 / 両側生体肺移植 / 肺移植後急性拒絶反応 / 抗ドナー抗体価 Less

Development of a method for preserving transplanted lung function using Gapmer-type antisense nucleic acidPrincipal Investigator
- Principal Investigator
  
  山根正修
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Shimane University
Elucidation of the role of S100A8/A9 in pulmonary ischemia-reperfusion injury and development of new therapeutic strategies
- Principal Investigator
  
  Okazaki Mikio
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Okayama University
Therapeutic effects of anti-HMGB1 monoclonal antibody on lung ischemia reperfusion injury in mice
- Principal Investigator
  
  OTANI SHINJI
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Ehime University
  Okayama University
Development of transplanted lung function-preserving method using a mouse model focusing on the anti-inflammatory related molecule Spred2Principal Investigator
- Principal Investigator
  
  Yamane Masaomi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Shimane University
  Okayama University
Mechanism and inhibition of ischemia reperfusion injury after lung transplantation from donation after cardiac death
- Principal Investigator
  
  OKAZAKI MIKIO
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Ehime University
Peculiar mechanisms of reperfusion injury and acute rejection after lung transplantationPrincipal Investigator
- Principal Investigator
  
  YAMANE Masaomi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University
臨床肺移植の予後改善を目指した移植免疫学的研究の新たな展開
- Principal Investigator
  
  小柴貴明
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
A large animal experimental study to establish a clinical applicable method for lung transplantation utilizing non-heart beating donors
- Principal Investigator
  
  DATE Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kyoto University
Research of the Airway Apoptosis after Lung Transplant Rejection
- Principal Investigator
  
  OKAZAKI Mikio
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Okayama University
basic research for ischemia reperfusion injury following lung transplantation using a mouse orthotropic lung transplant modelPrincipal Investigator
- Principal Investigator
  
  YAMANE Masaomi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University
The serum level of de novo donor specific antibody can predict acute rejection in lung transplantation.
- Principal Investigator
  
  SANO Yoshifumi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University
ラット肺移植モデルを用いた移植後虚血再環流障害における分子レベル変化の研究Principal Investigator
- Principal Investigator
  
  山根正修
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University
Experimental Study on Microthrombi Formation for Lung Transplantation from Non-Heart-Beating Donor
- Principal Investigator
  
  DATE Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University

All 2022 2021 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Inhibiting S100A8/A9 attenuates airway obstruction in a mouse model of heterotopic tracheal transplantation2022
- Author(s)
  Shimizu Dai、Okazaki Mikio、Sugimoto Seiichiro、Kinoshita Rie、Nakata Kentaro、Tanaka Shin、Hashimoto Kohei、Miyoshi Kentaroh、Yamane Masaomi、Matsukawa Akihiro、Sakaguchi Masakiyo、Toyooka Shinichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 629 Pages: 86-94
- DOI
  10.1016/j.bbrc.2022.08.087
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09164, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20K07636, KAKENHI-PROJECT-22H04923
[Journal Article] Functional Blockage of S100A8/A9 Ameliorates Ischemia Reperfusion Injury in the Lung2022
- Author(s)
  Nakata Kentaro、Okazaki Mikio、Sakaue Tomohisa、Kinoshita Rie、Komoda Yuhei、Shimizu Dai、Yamamoto Haruchika、Tanaka Shin、Suzawa Ken、Shien Kazuhiko、Miyoshi Kentaroh、Yamamoto Hiromasa、Ohara Toshiaki、Sugimoto Seiichiro、Yamane Masaomi、Matsukawa Akihiro、Sakaguchi Masakiyo、Toyooka Shinichi
- Journal Title
  
  Bioengineering
  
  Volume: 9 Issue: 11 Pages: 673-673
- DOI
  10.3390/bioengineering9110673
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09164, KAKENHI-PROJECT-20KK0203, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20K07636, KAKENHI-PROJECT-22H04923
[Journal Article] Protective effects of anti-HMGB1 monoclonal antibody on lung ischemia reperfusion injury in mice2021
- Author(s)
  Nakata Kentaro、Okazaki Mikio、Shimizu Dai、Suzawa Ken、Shien Kazuhiko、Miyoshi Kentaroh、Otani Shinji、Yamamoto Hiromasa、Sugimoto Seiichiro、Yamane Masaomi、Ousaka Daiki、Ohara Toshiaki、Matsukawa Akihiro、Nishibori Masahiro、Toyooka Shinichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 573 Pages: 164-170
- DOI
  10.1016/j.bbrc.2021.08.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09305, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20K09176
[Journal Article] EGR1-A NOVEL TARGET FOR AMELIORATING ACUTE ALLOGRAFT REJECTION IN AN EXPERIMENTAL LUNG-TRANSPLANT MODEL2012
- Author(s)
  Waki N, Yamane M, Yamamoto S, 他
- Journal Title
  
  Eur J Cardiothorac Surg
  
  Volume: 41(3) Pages: 669-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791311
[Journal Article] Peculiar mechanisms of graft recovery through anti-inflammatory responses after rat lung transplantation from donation after cardiac death2011
- Author(s)
  Yamamoto S, Okazaki M, Yamane M, 他
- Journal Title
  
  Transpl Immunol
  
  Volume: 26(2-3) Pages: 133-9
- NAID
  120005425638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791311
[Journal Article] Activations of mitogen-activated protein kinases and regulation of their downstream molecules after rat lung transplantation from donors after cardiac death2011
- Author(s)
  Yamamoto S, Yamane M, Yoshida O, 他
- Journal Title
  
  Transplant Proc
  
  Volume: 43(10) Pages: 3628-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791311
[Journal Article] Early effects of the ex vivo evaluation system on graft function after swine lung transplantation.2011
- Author(s)
  Otani S, Oto T, Kakishita T, Miyoshi K, Hori S, Yamane M, Toyooka S, Miyoshi S.
- Journal Title
  
  Eur J Cardiothorac Surg Epub ahead of print
- Data Source
  KAKENHI-PROJECT-20390367
[Journal Article] Effect of donor pre-mortem hypoxia and hypotension on graft function and start of warm ischemia in donation after cardiac death lung transplantation.2011
- Author(s)
  Miyoshi K, Oto T, Otani T, Tanaka S, Harada M, Kakishita T, Hori S, Waki N, Yamane M, Miyoshi S.
- Journal Title
  
  J Heart Lung Transplant 30(4)
  
  Pages: 445-451
- NAID
  130004505725
- Data Source
  KAKENHI-PROJECT-20390367
[Journal Article] Suppression of inflammatory cytokines during ex vivo lung perfusion with an absorbent membrane.2010
- Author(s)
  Kakishita T, Oto T, Hori S, Miyoshi K, Otani S, Yamamoto S, Waki N, Yoshida O, Okazaki M, Yamane M, Toyooka S, Sano Y, Miyoshi S.
- Journal Title
  
  Ann Thorac Surg 89(6)
  
  Pages: 1773-1779
- Data Source
  KAKENHI-PROJECT-20390367
[Presentation] 虚血再灌流肺障害にはMAPK/ERK経路の活性化が関与する2012
- Author(s)
  岡田真典, 山根正修, 伊賀徳周, 他
- Organizer
  日本肺および心肺移植研究会
- Place of Presentation
  仙台
- Year and Date
  2012-01-29
- Data Source
  KAKENHI-PROJECT-22791311
[Presentation] Effects of ex-vivo lung evaluation system on post-transplant graft function in swine donation after cardiac death (DCD) lung trasnsplantation.2010
- Author(s)
  Otani S, Oto T, Kakishita T, Harada M, Yamamoto S, Miyoshi K, Okazaki M, Waki N, Hori S, Sugimoto S, Soh J, Yamane M, Toyoka S, Miyoshi S.
- Organizer
  The 6^<th> Lung Transplant Conference
- Place of Presentation
  日仙台
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-20390367
[Presentation] 急性拒絶反応発症と抗ドナー特異的抗体価推移-急性拒絶反応発症を予見できるか2010
- Author(s)
  三好健太郎, 佐野由文, 大谷真二, 脇直久, 山根正修, 大藤剛宏, 三好新一郎
- Organizer
  第26回日本肺および心肺移植研究会
- Place of Presentation
  大阪大学中之島センター
- Year and Date
  2010-01-30
- Data Source
  KAKENHI-PROJECT-19591626
[Presentation] Does the ex-vivo lung evaluation system affect post-transplant graft dysfunction in swine donation after cardiac death (DCD) lung transplantation?2010
- Author(s)
  Otani S, Oto T, Kakishita T, Harada M, Yamamoto S, Miyoshi K, Okazaki M, Waki N, Hori S, Sugimoto S, Soh J, Yamane M, Toyoka S, Miyoshi S.
- Organizer
  30^<th> Annual Meeting and Scientific Sessions of International Society for Heart Lung Transplantation Society
- Data Source
  KAKENHI-PROJECT-20390367
[Presentation] 心停止ドナー肺移植後虚血再灌流障害からの回復における抗炎症性因子の重要性2009
- Author(s)
  山本澄治、山根正修
- Organizer
  第45回日本移植学会総会
- Place of Presentation
  東京
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-20790988
[Presentation] Egr-1ノックアウトマウスを用いた肺移植後再灌流障害2009
- Author(s)
  山本澄治、山根正修
- Organizer
  第45回日本移植学会総会
- Place of Presentation
  東京
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-20790988

1. TOMIOKA Shinichi (30397880)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
2. SANO Yoshifumi (60322228)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
3. DATE Hiroshi (60252962)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. OKAZAKI Mikio (50467750)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
5. BANDO Toru (20293954)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TSUYOSHI Shoji (80402840)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. OTO Takahiro (40452578)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
8. OTANI SHINJI (10770779)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 杉本誠一郎 (40570148)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
10. 阪口政清 (70379840)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. KOIKE Kaoru (10267164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. CHEN Fengshi (00452334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. FUJINAGA Takuji (00444456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OKAMOTO Toshihiro (90467465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 小柴貴明 (60362521)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 李頴 (30437222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 青江基 (80260660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 松川昭博 (90264283)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 坂上倫久 (20709266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 山本寛斉 (40467733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 木下理恵 (40518297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. 王登莉 (40815693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 西堀正洋 (50135943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 三好健太郎 (50534773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. DANIEL Kreisel

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. YOSHIDA Osamu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. YAMAMOTO Sumiharu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. KAWAKAMI Tetsuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yamane Masaomi 山根 正修

YAMANE Masaomi 山根 正修

Research Projects

Research Products

Co-Researchers

Development of a method for preserving transplanted lung function using Gapmer-type antisense nucleic acidPrincipal Investigator

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Development of transplanted lung function-preserving method using a mouse model focusing on the anti-inflammatory related molecule Spred2Principal Investigator

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Research Category

Review Section

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Principal Investigator

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Peculiar mechanisms of reperfusion injury and acute rejection after lung transplantationPrincipal Investigator

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basic research for ischemia reperfusion injury following lung transplantation using a mouse orthotropic lung transplant modelPrincipal Investigator

Principal Investigator

Project Period (FY)

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Principal Investigator

Project Period (FY)

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ラット肺移植モデルを用いた移植後虚血再環流障害における分子レベル変化の研究Principal Investigator

Principal Investigator

Project Period (FY)

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Research Field

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Principal Investigator

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Research Institution

[Journal Article] Inhibiting S100A8/A9 attenuates airway obstruction in a mouse model of heterotopic tracheal transplantation2022

Author(s)

Journal Title

DOI

Data Source

Yamane Masaomi 山根正修

YAMANE Masaomi 山根正修