SUZUKI Mari 鈴木マリ

Researcher Number	20455405
Other IDs	https://orcid.org/0000-0001-7495-1675
Affiliation (based on the past Project Information) *help	2023: 公益財団法人東京都医学総合研究所, 疾患制御研究分野, 主任研究員 2020 – 2021: 公益財団法人東京都医学総合研究所, 疾患制御研究分野, 主任研究員 2016 – 2021: 公益財団法人東京都医学総合研究所, 運動・感覚システム研究分野, 主任研究員 2015: 大阪大学, 医学系研究科, 特任助教 2011: (独)国立精神・神経医療研究センター, 神経研究所疾病研究第四部, 外来研究員 2010: 独立行政法人国立精神・神経医療研究センター, 神経研究所・疾病研究第四部, 外来研究員
Review Section/Research Field	Principal Investigator Neurology / Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 52020:Neurology-related Except Principal Investigator Medium-sized Section 52:General internal medicine and related fields / Neurology
Keywords	Principal Investigator ショウジョウバエ / ライソソーム病 / 脂質 / αシヌクレイン / レビー小体型認知症 / パーキンソン病 / 神経変性疾患 / Rubicon / ポリグルタミン病 / 老化 / オートファジー / プリオノイド株 … More Except Principal Investigator … More 凝集 / αシヌクレイン / シヌクレイノパチー / ショウジョウバエ / 伝播 / 脳神経疾患 / 神経科学 / 分子デザイン / ペプチド / 治療薬 / アミロイド / 蛋白質 / ポリグルタミン病 / 神経変性疾患 Less

糖尿病性神経障害におけるグリア細胞プロテオスタシス変容の分子機構とその役割Principal Investigator
- Principal Investigator
  
  鈴木マリ
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Mechanism of age-related decline of autophagy and treatment for neurodegenerative diseases through its regulationPrincipal Investigator
- Principal Investigator
  
  SUZUKI Mari
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Exploration of master genes for disease transmission in synucleinopathies
- Principal Investigator
  
  Sugie Atsushi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Niigata University
Analyses of the effect of lipid interactions on alpha-synuclein toxic conversionPrincipal Investigator
- Principal Investigator
  
  SUZUKI Mari
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
In vivo analysis of prion-like conversion and transmission of alpha-SynucleinPrincipal Investigator
- Principal Investigator
  
  SUZUKI Mari
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
  Osaka University
Development of a drug for the polyglutamine diseases by molecular design of chemical analogues of the aggregation inhibitor peptide QBP1
- Principal Investigator
  
  NAGAI Yoshitaka
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  National Center of Neurology and Psychiatry

All 2022 2021 2020 2019 2018 2017 2016 2015 2011

All Journal Article Presentation

[Journal Article] Roles of α-Synuclein and Disease-Associated Factors in Drosophila Models of Parkinson’s Disease2022
- Author(s)
  Suzuki Mari、Sango Kazunori、Nagai Yoshitaka
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 3 Pages: 1519-1519
- DOI
  10.3390/ijms23031519
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07987, KAKENHI-PROJECT-20K07773, KAKENHI-PROJECT-21H02840
[Journal Article] 老化およびアルツハイマー病に対するNADと前駆体の効果について2022
- Author(s)
  大場柾樹、福井浩二、三五一憲、鈴木マリ
- Journal Title
  
  ビタミン
  
  Volume: 96 Pages: 7-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07987
[Journal Article] Divergent CPEB prion-like domains reveal different assembly mechanisms for a generic amyloid-like fold2021
- Author(s)
  Hervas R, Fernandez-Ramirez MC, Galera-Prat A, Suzuki M, Nagai Y, Bruix M, Menendez M, Laurents DV, Carrion-Vazquez M
- Journal Title
  
  BMC Biology
  
  Volume: 19 Issue: 1 Pages: 1-14
- DOI
  10.1186/s12915-021-00967-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07987, KAKENHI-PLANNED-20H05927
[Journal Article] Dataset on the effect of Rubicon overexpression on polyglutamine-induced locomotor dysfunction in Drosophila2021
- Author(s)
  Oba Masaki、Fukui Koji、Sango Kazunori、Suzuki Mari
- Journal Title
  
  Data in Brief
  
  Volume: 37 Pages: 107222-107222
- DOI
  10.1016/j.dib.2021.107222
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07987, KAKENHI-PROJECT-20J22554, KAKENHI-PROJECT-20K07773
[Journal Article] Glial insulin regulates cooperative or antagonistic Golden goal/Flamingo interactions during photoreceptor axon guidance2021
- Author(s)
  Takechi Hiroki、Hakeda-Suzuki Satoko、Nitta Yohei、Ishiwata Yuichi、Iwanaga Riku、Sato Makoto、Sugie Atsushi、Suzuki Takashi
- Journal Title
  
  eLife
  
  Volume: 10
- DOI
  10.7554/elife.66718
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14835, KAKENHI-PROJECT-18J00367, KAKENHI-PROJECT-18K06250, KAKENHI-PROJECT-19K22592, KAKENHI-PUBLICLY-19H04771, KAKENHI-PROJECT-23K20226, KAKENHI-PROJECT-23K21312
[Journal Article] Arginine is a disease modifier for polyQ disease models that stabilizes polyQ protein conformation.2020
- Author(s)
  Minakawa EN, Popiel HA, Tada M, Takahashi T, Yamane H, Saitoh Y, Takahashi Y, Ozawa D, Takeda A, Takeuchi T, Okamoto Y, Yamamoto K, Suzuki M, Fujita H, Ito C, Yagihara H, Saito Y, Watase K, Adachi H, Katsuno M, Mochizuki H, Shiraki K, Sobue G, Toda T, Wada K, Onodera O, Nagai Y.
- Journal Title
  
  Brain
  
  Volume: 143 Issue: 6 Pages: 1811-1825
- DOI
  10.1093/brain/awaa115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07970, KAKENHI-PROJECT-19K07987, KAKENHI-PROJECT-20K07737, KAKENHI-PROJECT-17K09755, KAKENHI-PLANNED-20H05927
[Journal Article] Arylsulfatase A, a genetic modifier of Parkinson's disease, is an α-synuclein chaperone.2019
- Author(s)
  J. S. Lee, K. Kanai, M. Suzuki, W. S. Kim, H. S. Yoo, Y. Fu, D-K. Kim, B. C. Jung, M. Choi, K. W. Oh, Y. Li, M. Nakatani, T. Nakazato, S. Sekimoto, M. Furuyama, H. Yoshino, S. Kubo, K. Nishioka, R. Sakai, M. Ueyama, H. Mochizuki, H-J. Lee, S. P. Sardi, G. M. Halliday, Y. Nagai, P. H. Lee, N. Hattori, S-J. Lee
- Journal Title
  
  Brain
  
  Volume: 142 Issue: 9 Pages: 2845-59
- DOI
  10.1093/brain/awz205
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07823, KAKENHI-PROJECT-19K07987, KAKENHI-PROJECT-19K08003, KAKENHI-PROJECT-17K09811, KAKENHI-PROJECT-17K19658, KAKENHI-PUBLICLY-17H05699, KAKENHI-PROJECT-16H05325
[Journal Article] Lipids as trans-acting effectors for α-synuclein in the pathogenesis of Parkinson’s disease2019
- Author(s)
  Ikenaka K, Suzuki M, Mochizuki H, Nagai Y
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 13 Pages: 693-693
- DOI
  10.3389/fnins.2019.00693
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07987, KAKENHI-PROJECT-17K19658, KAKENHI-PUBLICLY-17H05699, KAKENHI-PROJECT-16H05325
[Journal Article] Glycolaldehyde induces sensory neuron death through activation of the c-Jun N-terminal kinase and p-38 MAP kinase pathways.2019
- Author(s)
  Akamine T, Takaku S, Suzuki M, Niimi N, Yako H, Matoba K, Kawanami D, Utsunomiya K, Nishimura R, Sango K
- Journal Title
  
  Histochemistry and cell biology
  
  Volume: 153 Issue: 2 Pages: 111-119
- DOI
  10.1007/s00418-019-01830-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07987, KAKENHI-PROJECT-19K08714, KAKENHI-PROJECT-18K15985, KAKENHI-PROJECT-20K07773, KAKENHI-PROJECT-20K16127
[Journal Article] E46K mutantα-synuclein is more degradation resistant and exhibits greater toxic effects than wild-typeα-synuclein in Drosophila models of Parkinson's disease.2019
- Author(s)
  R. Sakai, M. Suzuki, M. Ueyama, T. Takeuchi, E. N. Minakawa, H. Hayakawa, K. Baba, H. Mochizuki, Y. Nagai
- Journal Title
  
  PLoS ONE
  
  Volume: 14 Issue: 6 Pages: e0218261-e0218261
- DOI
  10.1371/journal.pone.0218261
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07823, KAKENHI-PROJECT-19K07987, KAKENHI-PROJECT-17K19658, KAKENHI-PUBLICLY-17H05699, KAKENHI-PROJECT-16H05325
[Journal Article] Suppression of autophagic activity by Rubicon is a signature of aging.2019
- Author(s)
  Nakamura S, Oba M, Suzuki M, Takahashi A, Yamamuro T, Fujiwara M, Ikenaka K, Minami S, Tabata N, Yamamoto K, Kubo S, Tokumura A, Akamatsu K, Miyazaki Y, Kawabata T, Hamasaki M, Fukui K, Sango K, Watanabe Y, Takabatake Y, Kitajima T, Okada Y, Mochizuki H, Isaka Y, Antebi A, Yoshimori T.
- Journal Title
  
  Nat Commun
  
  Volume: 10 Issue: 1 Pages: 847-847
- DOI
  10.1038/s41467-019-08729-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07505, KAKENHI-PROJECT-26251020, KAKENHI-PROJECT-16H06161, KAKENHI-PROJECT-17H05064, KAKENHI-PROJECT-17K16134, KAKENHI-PROJECT-19K07987, KAKENHI-PLANNED-18H05549, KAKENHI-PROJECT-16K07048
[Journal Article] オートファジー抑制蛋白質Rubiconの発現抑制はポリグルタミン病モデルショウジョウバエの神経症状を改善させる2018
- Author(s)
  大場柾樹, 永井義隆, 福井浩二, 三五一憲, 鈴木マリ
- Journal Title
  
  日本病態生理学会雑誌
  
  Volume: 27 Pages: 28-32
- Data Source
  KAKENHI-PROJECT-17K16134
[Journal Article] Parkinson’s disease-linked DNAJC13 mutation aggravates α-synuclein-induced neurotoxicity through perturbation of endosomal trafficking.2018
- Author(s)
  Yoshida S, Hasegawa T, Suzuki M, Sugeno N, Kobayashi J, Ueyama M, Fukuda M, Ido-Fujibayashi A, Sekiguchi K, Ezura M, Kikuchi A, Baba T, Takeda A, Mochizuki H, Nagai Y and Aoki M.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 27 Issue: 5 Pages: 823-836
- DOI
  10.1093/hmg/ddy003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09744, KAKENHI-PROJECT-17K09745, KAKENHI-PROJECT-17K19658, KAKENHI-PROJECT-17K16134, KAKENHI-PROJECT-16H05325, KAKENHI-PUBLICLY-17H05682, KAKENHI-PUBLICLY-17H05683, KAKENHI-PROJECT-26461303, KAKENHI-PROJECT-15K19502, KAKENHI-PROJECT-17K09789, KAKENHI-PROJECT-15K09331
[Journal Article] A spontaneously immortalized Schwann cell line from aldose reductase-deficient mice as a useful tool for studying polyol pathway and aldehyde metabolism.2018
- Author(s)
  2.Niimi N, Yako H, Takaku S, Kato H, Matsumoto T, Nishito Y, Watabe K, Ogasawara S, Mizukami H, Yagihashi S, Chung SK, Sango K.
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 印刷中 Pages: 97-106
- DOI
  10.1016/j.neuint.2017.12.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07048, KAKENHI-PROJECT-17K19658, KAKENHI-PROJECT-17K16134, KAKENHI-PROJECT-16H05325, KAKENHI-PROJECT-15K19502
[Journal Article] ショウジョウバエを用いたパーキンソン病の病態解明2017
- Author(s)
  堺竜介、鈴木マリ、永井義隆
- Journal Title
  
  医学のあゆみ
  
  Volume: 262(6) Pages: 641-646
- Data Source
  KAKENHI-PROJECT-15K19502
[Journal Article] ショウジョウバエを用いたパーキンソン病の病態解明2017
- Author(s)
  堺竜介、鈴木マリ、永井義隆
- Journal Title
  
  医学のあゆみ
  
  Volume: 262(6) Pages: 641-646
- Data Source
  KAKENHI-PROJECT-17K16134
[Journal Article] パーキンソン病リスク遺伝子GBAの機能喪失はα-シヌクレインの異常構造変化を促進して神経変性を悪化させる2016
- Author(s)
  鈴木マリ、藤掛伸宏、武内敏秀、香山(古金谷)綾子、中嶋和紀、平林義雄、和田圭司、永井義隆
- Journal Title
  
  日本病態生理学会雑誌
  
  Volume: 25 Pages: 36-44
- Data Source
  KAKENHI-PROJECT-15K19502
[Journal Article] Studying human neurodegenerative diseases using Drosophila melanogaster2016
- Author(s)
  鈴木マリ、永井義隆
- Journal Title
  
  生体の科学
  
  Volume: 67 Issue: 6 Pages: 589-595
- DOI
  10.11477/mf.2425200559
- ISSN
  0370-9531, 1883-5503
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-15K19502
[Journal Article] Molecular Basis of Orb2 Amyloidogenesis and Blockade of Memory Consolidation2016
- Author(s)
  Hervas R, Li L, Majumdar A, Fernandez-Ramirez Mdel C, Unruh JR, Slaughter BD, Galera-Prat A, Santana E, Suzuki M, Nagai Y, Bruix M, Casas-Tinto S, Menendez M, Laurents DV, Si K, Carrio-Vazquez M.
- Journal Title
  
  PLoS Biol
  
  Volume: 26 Issue: 1 Pages: e1002361-e1002361
- DOI
  10.1371/journal.pbio.1002361
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19502, KAKENHI-PROJECT-26670446
[Journal Article] Glucocerebrosidase deficiency accelerates the accumulation of proteinase K-resistant α-synuclein and aggravates neurodegeneration in a Drosophila model of Parkinson's disease.2015
- Author(s)
  Suzuki M, Fujikake N, Takeuchi T, Kohyama-Koganeya A, Nakajima K, Hirabayashi Y, Wada K, Nagai Y.
- Journal Title
  
  Hum Mol Genet. 2015 Dec 1;24(23):6675-86
  
  Volume: 24 Issue: 23 Pages: 6675-6686
- DOI
  10.1093/hmg/ddv372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19016, KAKENHI-PROJECT-15K19502, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-26670446, KAKENHI-PROJECT-26713030
[Journal Article] Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level.2015
- Author(s)
  Takeuchi T, Suzuki M, Fujikake N, Popiel HA, Kikuchi H, Futaki S, Wada K, Nagai Y
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: in press Issue: 19
- DOI
  10.1073/pnas.1412651112
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25110741, KAKENHI-PROJECT-15K19502, KAKENHI-PROJECT-24591287, KAKENHI-PROJECT-26670446, KAKENHI-PROJECT-26713030
[Journal Article] Normalization of overexpressed alpha-synuclein causing Parkinson’s disease by a moderate gene silencing with RNA interference.2015
- Author(s)
  Takahashi M., Suzuki M., Fukuoka M., Fujikake N., Watanabe S., Murata M., Wada K., Nagai Y., and *Hohjoh H.
- Journal Title
  
  Mol Ther Nucleic Acids
  
  Volume: 4 Pages: e241-e241
- DOI
  10.1038/mtna.2015.14
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390226, KAKENHI-PROJECT-15K19502, KAKENHI-PROJECT-25670428, KAKENHI-PROJECT-26670446, KAKENHI-PROJECT-25871169
[Presentation] オートファジー抑制因子 Rubicon の加齢に伴う翻訳後修飾変化の解析2022
- Author(s)
  大場柾樹、進藤真由美、福井浩二、三五一憲、鈴木マリ
- Organizer
  第30回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07987
[Presentation] 糖尿病性神経障害モデルショウジョウバエにおけるグリア細胞プロテオスタシスの役割2022
- Author(s)
  鈴木マリ、黒見坦、進藤真由美、新見直子、齊藤実、三五一憲
- Organizer
  第30回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07987
[Presentation] Tau発現ショウジョウバエにおけるMetformin, Pioglitazoneの治療効果の検討2021
- Author(s)
  坂田望、木村真梨、大場柾樹、福井浩二、三五一憲、鈴木マリ
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07987
[Presentation] 食餌制限が神経変性疾患モデルショウジョウバエの神経変性を改善する分子メカニズムの解明.2020
- Author(s)
  鈴木マリ, Anne-Marie Neumann, 斉藤勇二, 藤掛伸宏, 和田圭司, 三五一憲, 永井義隆
- Organizer
  第34回日本糖尿病・肥満動物学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K07987
[Presentation] オートファジー抑制因子Rubiconの発現抑制によるポリグルタミン病の改善2020
- Author(s)
  鈴木マリ
- Organizer
  第63回日本神経化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07987
[Presentation] Proteostasis in aging and neurodegenerative diseases.2019
- Author(s)
  Suzuki M.
- Organizer
  NEURO2019（第42回日本神経科学大会・第62回日本神経化学会大会）
- Invited
- Data Source
  KAKENHI-PROJECT-19K07987
[Presentation] ポリグルタミン病モデルショウジョウバエの神経症状はオートファジー抑制蛋白質Rubiconの発現抑制により改善する.2019
- Author(s)
  大場柾樹, 永井義隆, 福井浩二, 三五一憲, 鈴木マリ
- Organizer
  第9回認知症研究を知る若手研究者の集まり
- Data Source
  KAKENHI-PROJECT-19K07987
[Presentation] Knockdown of Rubicon, a negative regulator of autophagy, suppresses polyglutamine-induced toxicity in Drosophila.2019
- Author(s)
  Oba M, Nagai Y, Fukui K, Sango K, Suzuki M
- Organizer
  49th Annual Meeting of Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07987
[Presentation] Therapeutic effects of Rubicon knockdown in a Drosophila model of polyglutamine disease.2019
- Author(s)
  Suzuki M*, Oba M, Nagai Y, Fukui K, Sango K
- Organizer
  Keystone Symposia “Neurodegenerative Diseases: New Insights and Therapeutic Opportunities”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07987
[Presentation] オートファジー抑制蛋白質Rubiconの発現抑制は野生型ショウジョウバエの寿命を延長させる.2019
- Author(s)
  大場柾樹, 永井義隆, 福井浩二, 三五一憲, 鈴木マリ
- Organizer
  第29回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07987
[Presentation] ポリグルタミン病モデルショウジョウバエの神経症状はオートファジー抑制因子Rubiconの発現抑制により改善する.2019
- Author(s)
  大場柾樹, 永井義隆, 福井浩二, 三五一憲, 鈴木マリ
- Organizer
  首都大学東京バイオコンファレンス2019
- Data Source
  KAKENHI-PROJECT-19K07987
[Presentation] Dietary yeast restriction attenuates polyglutamine toxicity via insulin-like signaling and immune signaling in Drosophila2019
- Author(s)
  Suzuki M, Neumann A-M, Saitoh Y, Fujikake N, Wada K, K. Sango K, Nagai Y
- Organizer
  49th Annual Meeting of Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07987
[Presentation] ショウジョウバエを用いた神経変性疾患研究.2019
- Author(s)
  鈴木マリ
- Organizer
  第789回九州大学生体防御医学研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K07987
[Presentation] ショウジョウバエを用いた神経変性疾患研究2018
- Author(s)
  鈴木マリ
- Organizer
  第4回日本ミエリン研究会大会
- Data Source
  KAKENHI-PROJECT-17K16134
[Presentation] DNAJC13 mutation aggravates alpha-synuclein-induced toxicity through perturbation of trafficking.2018
- Author(s)
  吉田隼, 長谷川隆文, 鈴木マリ, 菅野直人, 小林潤平, 上山盛夫, 福田光則, 藤林明美, 関口清俊, 江面道典, 菊池昭夫, 馬場徹, 武田篤, 望月秀樹, 永井義隆, 青木正志
- Organizer
  第59回神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K16134
[Presentation] Knockdown of Rubicon extends lifespan and attenuates polyglutamine toxicity in Drosophila2018
- Author(s)
  Suzuki M, Oba M, Fukui K, Nagai Y, Sango K
- Organizer
  第59回神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K16134
[Presentation] オートファジー抑制蛋白質Rubiconの発現抑制によるポリグルタミン病モデルの症状改善2018
- Author(s)
  大場柾樹, 永井義隆, 福井浩二, 三五一憲, 鈴木マリ
- Organizer
  第37回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16134
[Presentation] Establishment of α-synuclein transgenic Drosophila model by site-specific transgenesis2018
- Author(s)
  堺竜介, 鈴木マリ, 上山盛夫, 武内敏秀, 永井義隆, 望月秀樹
- Organizer
  第59回神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K16134
[Presentation] オートファジー抑制蛋白質Rubiconの発現抑制はポリグルタミン病モデルショウジョウバエの神経症状を改善させる2018
- Author(s)
  大場柾樹, 永井義隆, 福井浩二, 三五一憲, 鈴木マリ
- Organizer
  第28回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-17K16134
[Presentation] オートファジー抑制蛋白質Rubiconの発現抑制はポリグルタミン病モデルショウジョウバエの神経症状を改善させる2018
- Author(s)
  大場柾樹, 永井義隆, 福井浩二, 三五一憲, 鈴木マリ
- Organizer
  第41回日本神経科学会大会
- Data Source
  KAKENHI-PROJECT-17K16134
[Presentation] パーキンソン病におけるαシヌクレイン－脂質相互作用の役割.2017
- Author(s)
  鈴木マリ, 永井義隆
- Organizer
  第12回臨床ストレス応答学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-15K19502
[Presentation] パーキンソン病におけるαシヌクレイン－脂質相互作用の役割.2017
- Author(s)
  鈴木マリ, 永井義隆.
- Organizer
  第12回臨床ストレス応答学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K16134
[Presentation] GBA機能喪失はα-シヌクレインの異常構造変化を促進して神経変性を悪化させる.2017
- Author(s)
  鈴木マリ, 藤掛伸宏, 武内敏秀, 香山（古金谷）綾子, 中嶋和紀, 平林義雄, 和田圭司, 三五一憲, 永井義隆.
- Organizer
  第36回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-15K19502
[Presentation] Dietary restriction improves misfolding protein-related neurodegeneration in Drosophila.2017
- Author(s)
  Mari Suzuki, Anne-Marie Neumann, Yuji Saitoh, Nobuhiro Fujikake, Keiji Wada, Kazunori Sango, Yoshitaka Nagai.
- Organizer
  Keystone Symposia “Aging and Mechanisms of Aging-Related Disease”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19502
[Presentation] Improvement of misfolding protein-induced neurodegeneration by dietary restriction in Drosophila.2017
- Author(s)
  Mari Suzuki, Anne-Marie Neumann, Yuji Saitoh, Nobuhiro Fujikake, Keiji Wada, Kazunori Sango, Yoshitaka Nagai.
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19502
[Presentation] 食餌制限は神経変性疾患モデルショウジョウバエの神経変性を改善する.2017
- Author(s)
  鈴木マリ, Anne-Marie Neumann, 斉藤勇二, 藤掛伸宏, 和田圭司, 三五一憲, 永井義隆.
- Organizer
  第27回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-15K19502
[Presentation] Dietary restriction improves neurodegeneration in Drosophila models of neurodegenerative diseases.2017
- Author(s)
  Mari Suzuki, Anne-Marie Neumann, Yuji Saitoh, Nobuhiro Fujikake, Keiji Wada, Kazunori Sango, Yoshitaka Nagai.
- Organizer
  EMBO/EMBL Symposium “Mechanisms of Neurodegeneration”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19502
[Presentation] Dietary restriction improves neurodegeneration in Drosophila models of neurodegenerative diseases.2017
- Author(s)
  Mari Suzuki, Anne-Marie Neumann, Yuji Saitoh, Nobuhiro Fujikake, Keiji Wada, Kazunori Sango, Yoshitaka Nagai.
- Organizer
  EMBO/EMBL Symposium “Mechanisms of Neurodegeneration”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16134
[Presentation] GBA機能喪失はα-シヌクレインの異常構造変化を促進して神経変性を悪化させる.2017
- Author(s)
  鈴木マリ, 藤掛伸宏, 武内敏秀, 香山（古金谷）綾子, 中嶋和紀, 平林義雄, 和田圭司, 三五一憲, 永井義隆.
- Organizer
  第36回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16134
[Presentation] Improvement of misfolding protein-induced neurodegeneration by dietary restriction in Drosophila.2017
- Author(s)
  Mari Suzuki, Anne-Marie Neumann, Yuji Saitoh, Nobuhiro Fujikake, Keiji Wada, Kazunori Sango, Yoshitaka Nagai.
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16134
[Presentation] Dietary restriction improves misfolding protein-related neurodegeneration in Drosophila.2017
- Author(s)
  Mari Suzuki, Anne-Marie Neumann, Yuji Saitoh, Nobuhiro Fujikake, Keiji Wada, Kazunori Sango, Yoshitaka Nagai.
- Organizer
  Keystone Symposia “Aging and Mechanisms of Aging-Related Disease”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16134
[Presentation] 食餌制限は神経変性疾患モデルショウジョウバエの神経変性を改善する.2017
- Author(s)
  鈴木マリ, Anne-Marie Neumann, 斉藤勇二, 藤掛伸宏, 和田圭司, 三五一憲, 永井義隆.
- Organizer
  第27回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-17K16134
[Presentation] GBA deficiency accelerates α-synuclein prion-like conversion and promotes its neurotoxicity2016
- Author(s)
  鈴木マリ、藤掛伸宏、武内敏秀、香山(古金谷)綾子、中嶋和紀、平林義雄、和田圭司、永井義隆
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K19502
[Presentation] パーキンソン病リスク遺伝子GBAの機能喪失はα-シヌクレインの異常構造変化を促進して神経変性を悪化させる2016
- Author(s)
  鈴木マリ、藤掛伸宏、武内敏秀、香山(古金谷)綾子、中嶋和紀、平林義雄、和田圭司、永井義隆
- Organizer
  第26回日本病態生理学会大会
- Place of Presentation
  金沢医科大学（石川県河北郡）
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-15K19502
[Presentation] グルコセレブロシダーゼ機能欠失はαシヌクレインの異常構造変化を促進して神経変性を増悪する2016
- Author(s)
  鈴木マリ、藤掛伸宏、武内敏秀、香山(古金谷)綾子、中嶋和紀、平林義雄、和田圭司、永井義隆
- Organizer
  第10回パーキンソン病・運動障害疾患コングレス
- Place of Presentation
  京都ホテルオークラ（京都府京都市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K19502
[Presentation] Effect of dietary conditions on Drosophila models of neurodegenerative diseases2015
- Author(s)
  Mari Suzuki, Anne-Marie Neumann, Yuji Saitoh, Nobuhiro Fujikake, Keiji Wada, Yoshitaka Nagai
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  新潟コンベンションセンター（新潟市中央区）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-15K19502
[Presentation] 神経変性疾患モデルショウジョウバエの神経変性は過栄養摂取により増悪する2015
- Author(s)
  永井義隆、鈴木マリ、Neumann Anne-Marie、藤掛伸宏、和田圭司
- Organizer
  第34回日本認知症学会学術集会
- Place of Presentation
  リンクステーションホール青森（青森市堤町）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K19502
[Presentation] 高栄養負荷は神経変性疾患モデルショウジョウバエにおける神経変性を増悪する2011
- Author(s)
  鈴木マリ、藤掛伸宏、和田圭司、永井義隆
- Organizer
  第34回日本神経科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22659172
[Presentation] 高栄養負荷は神経変性疾患モデルショウジョウバエにおける神経変性を増悪する2011
- Author(s)
  鈴木マリ
- Organizer
  第34回日本神経科学会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-22659172

1. NAGAI Yoshitaka (60335354)

# of Collaborated Projects: 4 results

# of Collaborated Products: 31 results
2. SAKAI Ryusuke

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. OBA Masaki

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. Sugie Atsushi (50777000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ADACHI Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. NAKAJIMA Kazuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. WATANABE Yoshihisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 上山盛夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 新田陽平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 平林義雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 北条浩彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 長谷川隆文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 三五一憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SUZUKI Mari 鈴木 マリ

Research Projects

Research Products

Co-Researchers

糖尿病性神経障害におけるグリア細胞プロテオスタシス変容の分子機構とその役割Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Mechanism of age-related decline of autophagy and treatment for neurodegenerative diseases through its regulationPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Exploration of master genes for disease transmission in synucleinopathies

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Analyses of the effect of lipid interactions on alpha-synuclein toxic conversionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In vivo analysis of prion-like conversion and transmission of alpha-SynucleinPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Development of a drug for the polyglutamine diseases by molecular design of chemical analogues of the aggregation inhibitor peptide QBP1

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Roles of α-Synuclein and Disease-Associated Factors in Drosophila Models of Parkinson’s Disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 老化およびアルツハイマー病に対するNADと前駆体の効果について2022

Author(s)

Journal Title

Data Source

[Journal Article] Divergent CPEB prion-like domains reveal different assembly mechanisms for a generic amyloid-like fold2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dataset on the effect of Rubicon overexpression on polyglutamine-induced locomotor dysfunction in Drosophila2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glial insulin regulates cooperative or antagonistic Golden goal/Flamingo interactions during photoreceptor axon guidance2021

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Journal Title

DOI

Data Source

[Journal Article] Arginine is a disease modifier for polyQ disease models that stabilizes polyQ protein conformation.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Arylsulfatase A, a genetic modifier of Parkinson's disease, is an α-synuclein chaperone.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lipids as trans-acting effectors for α-synuclein in the pathogenesis of Parkinson’s disease2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycolaldehyde induces sensory neuron death through activation of the c-Jun N-terminal kinase and p-38 MAP kinase pathways.2019

SUZUKI Mari 鈴木マリ