Kamio Koichiro 神尾孝一郎

Researcher Number	20465305
Other IDs
Affiliation (Current)	2025: 日本医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 日本医科大学, 医学部, 准教授 2022 – 2023: 日本医科大学, 医学部, 准教授 2017 – 2022: 日本医科大学, 医学部, 講師 2013 – 2017: 日本医科大学, 医学部, 助教 2012: 日本医科大学, 医学部, 講師 2011: 日本医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related / Basic Section 56010:Neurosurgery-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach
Keywords	Principal Investigator 特発性肺線維症 / 制御性T細胞 / マイクロRNA / 肺線維化病態 / M2マクロファージ / 自然リンパ球 / 制御性Ｔ細胞 / MMP-13 / Macrophage polarization / PTEN … More / MAGI2 / macrophage polarization / 骨髄由来細胞 / 再生医療 / 自家骨髄細胞 / IL-10 / FGF9 / ブレオマイシン … More Except Principal Investigator 特発性肺線維症 / エクソソーム / 肺線維芽細胞 / Rho / 血管透過性 / 有害事象 / 間質性肺炎 / 薬剤性肺障害 / 細胞治療 / 感染 / トランスレーショナルリサーチ / 幹細胞 / 脳梗塞 / 免疫調整 / 幹細胞治療 / 脳卒中 / 肺炎 / ＥＭＴ / 肺線維症 / 細胞増殖 / Ⅰ型コラーゲン / 酸化ストレス / ディーゼル排気粒子 / 細胞遊走 / microRNA / マイクロRNA / 上皮間葉転換 / 筋線維芽細胞 / エンドスタチン / 心筋障害 / 臨床呼吸器学 / 内科系臨床医学 / 運動耐容能 / 心筋傷害 / 心血管併存症 / NT-proBNP / 高感度トロポニンT / COPD / ガレクチン-3 / 慢性閉塞性肺疾患 / cutis laxa / exosome / LTBP4 / 肺気腫 / ヒト肺線維芽細胞 / エラスチン / LTBP-4 / HDAC inhibitor / IPF / SPARC / XPLN / mTORC2 / fibrocyte / ピルフェニドン / 線維細胞 Less

肺線維症合併肺癌克服への新規治療戦略―制御性遺伝子ナノ粒子吸入による微小環境変容Principal Investigator
- Principal Investigator
  
  神尾孝一郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nippon Medical School
Rhoキナーゼによる薬剤性肺障害モデルの樹立と治療法の解明
- Principal Investigator
  
  柏田建
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nippon Medical School
肺線維化病態の新規治療戦略ー制御性遺伝子吸入と免疫担当細胞のクロストークの解明ーPrincipal Investigator
- Principal Investigator
  
  神尾孝一郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nippon Medical School
The crosstalk mechanisms between immunological cells responsible for fibrotic microenvironment and the effect of aging.Principal Investigator
- Principal Investigator
  
  KAMIO Koichiro
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nippon Medical School
Dental pulp-derived stem cell therapy for post-stroke pneumonia: Focusing on intrapulmonary immunity and exploring the possibility of therapeutic application.
- Principal Investigator
  
  Suda Satoshi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nippon Medical School
Exacerbation effects and molecular mechanism of diesel exhaust particles in pulmonary fibrosis
- Principal Investigator
  
  LI YINGJI
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Nippon Medical School
Mechanisms of endostatin and microRNAs in pulmonary fibrosis
- Principal Investigator
  
  Azuma Arata
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Cutis laxa類似病態の肺気腫：エクソソームによる診断とLTBP4補充療法
- Principal Investigator
  
  木田厚瑞
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Exploring the role of galectin-3 to elucidate the new mechanism of organ correlation between lung and heart in COPD
- Principal Investigator
  
  Hiramatsu Kumiko
- Project Period (FY)
  2016 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Investigation of the effects of autologous bone marrow and spleen cells on pulmonary fibrosisPrincipal Investigator
- Principal Investigator
  
  Kamio Koichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
The role of mTORC2-SPARC pathway in the pathogenesis of pulmonary fibrosis
- Principal Investigator
  
  Azuma Arata
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Involvement of bone marrow-derived fibrocyte in the pathogenesis of pulmonary fibrosis and the effect of newly developed anti-fibrotic agents
- Principal Investigator
  
  AZUMA Arata
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School

All 2024 2021 2020 2017 2016 2014 2013 Other

All Journal Article Presentation

[Journal Article] Exosome-Derived microRNA-22 Ameliorates Pulmonary Fibrosis by Regulating Fibroblast-to-Myofibroblast Differentiation in Vitro and in Vivo2020
- Author(s)
 Kuse Naoyuki、Kamio Koichiro、Azuma Arata、Matsuda Kuniko、Inomata Minoru、Usuki Jiro、Morinaga Akemi、Tanaka Toru、Kashiwada Takeru、Atsumi Kenichiro、Hayashi Hiroki、Saito Yoshinobu、Seike Masahiro、Gemma Akihiko
- Journal Title
 
 Journal of Nippon Medical School
 
 Volume: 87 Issue: 3 Pages: 118-128
- DOI
 10.1272/jnms.JNMS.2020_87-302
- NAID
 130007872706
- ISSN
 1345-4676, 1347-3409
- Year and Date
 2020-06-30
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-17K09675
[Journal Article] XPLN is modulated by HDAC inhibitors and negatively regulates SPARC expression by targeting mTORC2 in human lung fibroblasts2017
- Author(s)
  Koichiro Kamio, Arata Azuma, Jiro Usuki, Kuniko Matsuda, Minoru Inomata, Nobuhiko Nishijima, Shioto Itakura, Hiroki Hayashi, Takeru Kashiwada, Nariaki Kokuho, Kenichiro Atsumi, Tomoyoshi Yamaguchi, Kazue Fujita, Yoshinobu Saito, Shinji Abe, Kaoru Kubota, Akihiko Gemma
- Journal Title
  
  Pulmonary Pharmacology & Therapeutics
  
  Volume: 44 Pages: 61-69
- DOI
  10.1016/j.pupt.2017.03.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461201, KAKENHI-PROJECT-26461202, KAKENHI-PROJECT-15K19433
[Journal Article] Pirfenidone inhibits fibrocyte accumulation in the lungs in bleomycin-induced murine pulmonary fibrosis2014
- Author(s)
  Minoru Inomata, Koichiro Kamio, Arata Azuma, Kuniko Matsuda, Nariaki Kokuho, Yukiko Miura, Hiroki Hayashi, Takahito Nei, Kazue Fujita, Yoshinobu Saito and Akihiko Gemma
- Journal Title
  
  Respiratory Research
  
  Volume: 15巻 Issue: 1 Pages: 16-30
- DOI
  10.1186/1465-9921-15-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591163, KAKENHI-PROJECT-23790926
[Presentation] 肺線維化病態におけるMAGI2の関与についての検討2024
- Author(s)
  佐藤陽三、神尾孝一郎、久世眞之、松田久仁子、鏑木翔太、田中徹、宮永晃彦、田中庸介、齋藤好信、清家正博
- Organizer
  第64回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08614
[Presentation] MAGI2 Is Involved in the Pathogenesis of Pulmonary Fibrosis2024
- Author(s)
  Y. Sato, K. Kamio, N. Kuse, K. Matsuda, S. Kaburaki, T. Tanaka, A. Miyanaga, Y. Tanaka, Y. Saito, and M. Seike
- Organizer
  American Thoracic Society 2024 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08614
[Presentation] 自家骨髄細胞による肺線維症モデルマウスの病態改善効果に関する研究2021
- Author(s)
  神尾孝一郎、吾妻安良太、松田久仁子、猪俣稔、久世眞之、臼杵二郎、田中徹、柏田建、佐藤純平、西島伸彦、渥美健一郎、齋藤好信、清家正博、弦間昭彦
- Organizer
  第61回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08614
[Presentation] 自家骨髄細胞による肺線維症モデルマウスの病態改善効果に関する研究2021
- Author(s)
  神尾孝一郎、吾妻安良太、松田久仁子、猪俣稔、久世眞之、臼杵二郎、田中徹、柏田建、佐藤純平、西島伸彦、渥美健一郎、齋藤好信、清家正博、弦間昭彦
- Organizer
  第61回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08614
[Presentation] XPLN Negatively Regulates SPARC Expression by Targeting mTORC2 in Human Lung Fibroblasts2016
- Author(s)
  Koichiro Kamio, Arata Azuma, Jiro Usuki, Kuniko Matsuda, Minoru Inomata, Nobuhiko Nishijima, Shioto Itakura, Nariaki Kokuho, Hiroki Hayashi, Tomoyoshi Yamaguchi, Kazue Fujita, Yoshinobu Saito, Shinji Abe, Kaoru Kubota, Akihiko Gemma
- Organizer
  American Thoracic Society
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2016-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461201
[Presentation] XPLN Negatively Regulates SPARC Expression by Targeting mTORC2 in Human Lung Fibroblasts2016
- Author(s)
  Koichiro Kamio, Arata Azuma, Jiro Usuki, Kuniko Matsuda, Minoru Inomata, Nobuhiko Nishijima, Shioto Itakura, Nariaki Kokuho, Hiroki Hayashi, Tomoyoshi Yamaguchi, Kazue Fujita, Yoshinobu Saito, Shinji Abe, Kaoru Kubota, Akihiko Gemma
- Organizer
  American Thoracic Society
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2016-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461202
[Presentation] Pirfenidone Inhibits Bone Marrow-Derived Fibrocytes Influx into the Lungs in Bleomycin-induced Murine Pulmonary Fibrosis2013
- Author(s)
  Minoru Inomata, Koichiro Kamio, Kuniko Matsuda, Nariaki Kokuho, Yukiko Miura, Kazue Fujita, Yoshinobu Saito, Akihiko Gemma, Arata Azuma
- Organizer
  American Thoracic Society
- Place of Presentation
  米国フィラデルフィア
- Data Source
  KAKENHI-PROJECT-23591163
[Presentation] ブレオマイシン誘発肺障害モデルマウスにおけるピルフェニドンの骨髄由来fibrocyte抑制効果に関する検討2013
- Author(s)
  猪俣稔、神尾孝一郎、松田久仁子、國保成暁、根井貴仁、三浦由記子、藤田和恵、齋藤好信、弦間昭彦、吾妻安良太
- Organizer
  第53回日本呼吸域学会学術講演会
- Year and Date
  2013-04-20
- Data Source
  KAKENHI-PROJECT-23591163
[Presentation] Pirfenidone Inhibits Bone Marrow-Derived Fibrocytes Influx Into The Lungs In Bleomycin-Induced Murine Pulmonary Fibrosis2013
- Author(s)
  Minoru Inomata, Koichiro Kamio, Kuniko Matsuda, Nariaki Kokuho, Yukiko Miura, Kazue Fujita, Yoshinobu Saito, Akihiko Gemma, Arata Azuma
- Organizer
  American Thoracic Society Conference 2013
- Year and Date
  2013-05-22
- Data Source
  KAKENHI-PROJECT-23591163
[Presentation] ブレオマイシン誘発肺障害モデルマウスにおけるピルフェニドンの骨髄由来fibrocyte抑制効果に関する検討2013
- Author(s)
  猪俣稔、神尾孝一郎、松田久仁子、國保成暁、根井貴仁、三浦由記子、藤田和恵、齋藤好信、弦間昭彦、吾妻安良太
- Organizer
  第53回　日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591163
[Presentation] ブレオマイシン誘発肺障害モデルマウスにおけるピルフェニドンの骨髄由来fibrocyte抑制効果に関する検討
- Author(s)
  猪俣稔、神尾孝一郎、吾妻安良太
- Organizer
  日本呼吸器学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591163
[Presentation] Pirfenidone Inhibits Bone Marrow-Derived Fibrocytes Influx into the Lungs In Bleomycin-induced Murine Pulmonary Fibrosis
- Author(s)
  猪俣稔、神尾孝一郎、吾妻安良太
- Organizer
  American Thoracic Society
- Place of Presentation
  米国
- Data Source
  KAKENHI-PROJECT-23591163

1. AZUMA Arata (10184194)

# of Collaborated Projects: 7 results

# of Collaborated Products: 12 results
2. 木田厚瑞 (90142645)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 新井富生 (20232019)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 石井健男 (90445750)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MATSUDA Kuniko

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. Hiramatsu Kumiko (40409173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. LI YINGJI (60350039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Suda Satoshi (00366733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 石井正紀 (20724438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 別役智子 (60333605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 宮武佳子 (10267213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 川田智之 (00224791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 平田幸代 (40322515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 稲垣弘文 (50213111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 臼田実男 (60338803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 野呂林太郎 (50366738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 仁藤智香子 (30409172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 横堀将司 (70449271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 柏田建 (50754991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kamio Koichiro 神尾 孝一郎

Research Projects

Research Products

Co-Researchers

肺線維症合併肺癌克服への新規治療戦略―制御性遺伝子ナノ粒子吸入による微小環境変容Principal Investigator

Principal Investigator

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肺線維化病態の新規治療戦略ー制御性遺伝子吸入と免疫担当細胞のクロストークの解明ーPrincipal Investigator

Principal Investigator

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Review Section

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The crosstalk mechanisms between immunological cells responsible for fibrotic microenvironment and the effect of aging.Principal Investigator

Principal Investigator

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Principal Investigator

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Investigation of the effects of autologous bone marrow and spleen cells on pulmonary fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

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Principal Investigator

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[Journal Article] Exosome-Derived <i>microRNA</i>-<i>22</i> Ameliorates Pulmonary Fibrosis by Regulating Fibroblast-to-Myofibroblast Differentiation <i>in Vitro</i> and <i>in Vivo</i>2020

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ISSN

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[Journal Article] XPLN is modulated by HDAC inhibitors and negatively regulates SPARC expression by targeting mTORC2 in human lung fibroblasts2017

Author(s)

Journal Title

Kamio Koichiro 神尾孝一郎