Uchimura Arikuni 内村有邦

… Alternative Names

UCHIMURA Arikuni 内村有邦

内村有邦ウチムラアリクニ

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Researcher Number	20513063
Affiliation (Current)	2025: 公益財団法人放射線影響研究所, 分子生物科学部, 副部長 2025: 大阪大学, 大学院生命機能研究科, 招へい教員
Affiliation (based on the past Project Information) *help	2022 – 2024: 公益財団法人放射線影響研究所, 分子生物科学部, 室長 2016 – 2020: 大阪大学, 生命機能研究科, 招へい教員 2016: 大阪大学, 生命機能研究科, 助教 2016: 大阪大学, 大学院生命機能研究科, 助教 2012 – 2015: 大阪大学, 生命機能研究科, 特任助教(常勤) … More 2014: 大阪大学, 生命機能研究科, 助教 2012: 大阪大学, 生命機能研究科, 特任助教 2009 – 2010: Osaka University, 大学院・生命機能研究科, 特任研究員 Less
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Basic Section 63040:Environmental impact assessment-related / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Environmental impact assessment / Risk sciences of radiation and chemicals / Laboratory animal science / Evolutionary biology Except Principal Investigator Basic Section 63020:Radiation influence-related / Laboratory animal science / Medium-sized Section 63:Environmental analyses and evaluation and related fields / Laboratory animal science
Keywords	Principal Investigator 突然変異 / 生殖細胞 / モザイク変異 / 哺乳類 / リスク評価 / マウス / 胚発生 / 細胞系譜 / 次世代シーケンサー / 次世代影響 … More / 生殖系列 / 変異 / 動物モデル / 後世代影響 / 哺乳類モデル / 遺伝毒性試験 / 音声コミュニケーション / モデル動物 / マウス遺伝学 / 進化 … More Except Principal Investigator 体細胞変異 / 量的形質 / マウス / 突然変異 / 進化 / 疾患モデル / バイオドシメトリ / 変異シグネチャー / DNA複製 / ゲノム / 放射線被ばく / クローン造血 / バイオインフォーマティクス / 低線量率放射線影響 / オミクス解析 / 進化多様性 / ミュータジェネシス / 放射線 / 老化 / クローン化 / 悪性腫瘍 / 晩発障害 / DNA損傷 / 生活習慣病 / 多様性 / 遺伝学 / 塩基配列 / 生殖細胞 / DNAポリメラーゼ / 哺乳類 / 遺伝子 / 生殖系列 / エピスタシス / がん / 表現型 Less

Risk assessment of next-generation effects based on Whole Genome Sequencing at the T2T LevelPrincipal Investigator
- Principal Investigator
  
  内村有邦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63040:Environmental impact assessment-related
- Research Institution
  Radiation Effects Research Foundation
Analysis of changes in radiation-induced mutational signatures induced by DNA repair inhibitors and their impact on carcinogenic risk.
- Principal Investigator
  
  松田由喜子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Radiation Effects Research Foundation
Mechanisms of next generation inheritance of genomic information including hypervariable mega-genomic regionsPrincipal Investigator
- Principal Investigator
  
  内村有邦
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Radiation Effects Research Foundation
High-throughput and precision analysis of biological effects of low-dose-rate radiation.
- Principal Investigator
  
  権藤洋一
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 63:Environmental analyses and evaluation and related fields
- Research Institution
  Osaka University
Time-resolved biodosimetry based on clonal hematopoiesis and somatic mutations in atomic-bomb survivors
- Principal Investigator
  
  吉田健吾
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Radiation Effects Research Foundation
Whole-genome sequence analysis of radiation-induced mutations in human hematopoietic stem cells
- Principal Investigator
  
  田邉修
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Radiation Effects Research Foundation
Cell lineage analysis by using post-zygotic spontaneous mutationsPrincipal Investigator
- Principal Investigator
  
  UCHIMURA Arikuni
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Osaka University
Single molecular analysis of germline mutagenesis and risk assessment for future generationPrincipal Investigator
- Principal Investigator
  
  UCHIMURA Arikuni
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Environmental impact assessment
- Research Institution
  Osaka University
In vivo genotoxicity test focusing on mosaic mutations in germline cellsPrincipal Investigator
- Principal Investigator
  
  UCHIMURA Arikuni
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Osaka University
A life design model using mutator mice
- Principal Investigator
  
  YAGI Takeshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Osaka University
Novel animal model by using high germline mutation rate
- Principal Investigator
  
  YAGI Takeshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Osaka University
New mouse model for an aural communicationPrincipal Investigator
- Principal Investigator
  
  UCHIMURA Arikuni
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Osaka University
Production of new design mice by accumulation of mutations
- Principal Investigator
  
  YAGI Takeshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Osaka University
高頻度突然変異発生マウス系統を利用した実験室内哺乳類進化実験モデル系の構築Principal Investigator
- Principal Investigator
  
  内村有邦
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Evolutionary biology
- Research Institution
  Osaka University

All 2023 2022 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Spectra and characteristics of somatic mutations induced by ionizing radiation in hematopoietic stem cells2023
- Author(s)
  Matsuda Yukiko、Uchimura Arikuni、Satoh Yasunari、Kato Naohiro、Toshishige Masaaki、Kajimura Junko、Hamasaki Kanya、Yoshida Kengo、Hayashi Tomonori、Noda Asao、Tanabe Osamu
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 15
- DOI
  10.1073/pnas.2216550120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K12388, KAKENHI-PROJECT-23K28234
[Journal Article] 実験用マウスを用いた放射線被ばくの次世代遺伝影響の解析2020
- Author(s)
  佐藤康成、内村有邦
- Journal Title
  
  広島医学
  
  Volume: 73 Pages: 228-232
- Data Source
  KAKENHI-PROJECT-18K19340
[Journal Article] Characteristics of induced mutations in offspring derived from irradiated mouse spermatogonia and mature oocytes2020
- Author(s)
  Yasunari Satoh, Jun-ichi Asakawa, Mayumi Nishimura, Tony Kuo, Norio Shinkai, Harry M. Cullings, Yohei Minakuchi, Jun Sese, Atsushi Toyoda, Yoshiya Shimada, Nori Nakamura, Arikuni Uchimura
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 37-37
- DOI
  10.1038/s41598-019-56881-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19340, KAKENHI-PROJECT-16H06279
[Journal Article] 変異蓄積モデルを利用した生殖系列変異の後世代影響の解析2017
- Author(s)
  内村有邦、樋口真弓、八木健
- Journal Title
  
  放射線生物研究
  
  Volume: 52(4) Pages: 402-415
- NAID
  40021447934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05890
[Journal Article] 変異蓄積モデルを利用した生殖系列変異の後世代影響の解析2017
- Author(s)
  内村有邦、樋口真弓、八木健
- Journal Title
  
  放射線生物研究
  
  Volume: 52(4) Pages: 402-415
- NAID
  40021447934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K12205
[Journal Article] Delineation of a frequency-organized region isolated from the mouse primary auditory cortex.2015
- Author(s)
  Tsukano H, Horie M, Bo T, Uchimura A, Hishida R, Kudoh M, Takahashi K, Takebayashi H, Shibuki K
- Journal Title
  
  J Neurophysiol
  
  Volume: 印刷中 Issue: 7 Pages: 2900-2920
- DOI
  10.1152/jn.00932.2014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22115011, KAKENHI-PROJECT-24650235, KAKENHI-PROJECT-26830008, KAKENHI-PROJECT-26430011
[Journal Article] 集団遺伝学から考える脳の進化2015
- Author(s)
  内村有邦、八木健
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 33 Pages: 909-911
- Data Source
  KAKENHI-PROJECT-15K12205
[Journal Article] 集団遺伝学から考える脳の進化2015
- Author(s)
  内村有邦、八木健
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 33 Pages: 909-911
- Data Source
  KAKENHI-PROJECT-15K14368
[Journal Article] 生殖系列の変異率と変異蓄積マウス系統2015
- Author(s)
  内村有邦
- Journal Title
  
  実験医学
  
  Volume: 33 Pages: 3123-3126
- Data Source
  KAKENHI-PROJECT-15K12205
[Journal Article] 生殖系列の変異率と変異蓄積マウス系統2015
- Author(s)
  内村有邦
- Journal Title
  
  実験医学
  
  Volume: 33 Pages: 3123-3126
- Data Source
  KAKENHI-PROJECT-15K14368
[Journal Article] Germline mutation rates and the long-term phenotypic effects of mutation accumulation in wild-type laboratory mice and mutator mice2015
- Author(s)
  Arikuni Uchimura, Mayumi Higuchi, Yohei Minakuchi, Mizuki Ohno, Atsushi Toyoda, Asao Fujiyama, Ikuo Miura, Shigeharu Wakana, Jo Nishino, Takeshi Yagi
- Journal Title
  
  Genome Research
  
  Volume: 25 Issue: 8 Pages: 1125-1134
- DOI
  10.1101/gr.186148.114
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K12205, KAKENHI-PROJECT-15K14368, KAKENHI-PROJECT-221S0002, KAKENHI-PROJECT-26281022
[Journal Article] International Symposium on “Germline Mutagenesis and Biodiversification”2014
- Author(s)
  Arikuni Uchimura, Yuichiro Hara, Yoichi Gondo, Yusaku Nakabeppu
- Journal Title
  
  Genes Genet. Syst.
  
  Volume: 89 Issue: 2 Pages: 93-95
- DOI
  10.1266/ggs.89.93
- NAID
  130004687235
- ISSN
  1341-7568, 1880-5779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24650235, KAKENHI-PROJECT-25241016, KAKENHI-PROJECT-25640047
[Journal Article] Expansion of stochastic expression repertoire by tandem duplication in mouse Protocadherin-α cluster.2014
- Author(s)
  Kaneko R, Abe M, Hirabayashi T, Uchimura A, Sakimura K, Yanagawa Y, Yagi T.
- Journal Title
  
  Sci Rep.
  
  Volume: 4 Issue: 1 Pages: 6263-6263
- DOI
  10.1038/srep06263
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24500375, KAKENHI-PROJECT-24650235, KAKENHI-PROJECT-25640047, KAKENHI-PUBLICLY-26115516, KAKENHI-PROJECT-26350979, KAKENHI-PROJECT-26640007
[Presentation] X線照射によりマウス造血幹細胞に誘発される体細胞変異とクローン性増殖2023
- Author(s)
  松田由喜子、内村有邦、佐藤康成、加藤直広、利重匡亮、梶村順子、濱崎幹也、吉田健吾、林奉権、野田朝男、田邉修
- Organizer
  日本放射線影響学会第66会大会
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] Genome-wide frequencies and signatures of somatic mutations introduced by whole-body X-irradiation in mouse long-term hematopoietic stem cells2023
- Author(s)
  Matsuda Y, Uchimura A, Satoh Y, Kato N, Toshishige M, Kajimura J, Hamasaki K, Yoshida K, Hayashi T, Noda A, Tanabe O
- Organizer
  17th International Congress for Radiation Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] Genome-wide analysis of radiation-induced somatic mutations in mouse long-term hematopoietic stem cells2023
- Author(s)
  Matsuda Y, Uchimura A, Satoh Y, Kato N, Toshishige M, Kume K, Kajimura J, Hamasaki K, Yoshida K, Hayashi T, Noda A, Tanabe O
- Organizer
  75th Annual Meeting of the American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K28234
[Presentation] 全身X線照射後のマウス造血幹細胞の体細胞変異とクローン動態の全ゲノムシーケンスによる解析2023
- Author(s)
  松田由喜子、内村有邦、佐藤康成、加藤直広、利重匡亮、梶村順子、濱崎幹也、吉田健吾、林奉権、野田朝男、田邉修
- Organizer
  日本環境変異原ゲノム学会第52回大会
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] Longitudinal trajectories of clonal hematopoiesis before and after 3-Gy whole-body irradiation in mice2023
- Author(s)
  Yoshida K, Uchimura A, Satou Y, Matsuda Y, Tanabe O, Noda A, Misumi M, Kusunoki Y
- Organizer
  17th International Congress of Radiation Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K28234
[Presentation] 全身X線照射後のマウス造血幹細胞の体細胞変異とクローン動態の全ゲノムシーケンスによる解析2023
- Author(s)
  松田由喜子、内村有邦、佐藤康成、加藤直広、利重匡亮、梶村順子、濱崎幹也、吉田健吾、林奉権、野田朝男、田邉修
- Organizer
  日本環境変異原ゲノム学会第52回大会
- Data Source
  KAKENHI-PROJECT-23K28234
[Presentation] 全身X線照射後のマウス骨髄細胞におけるリンパ球受容体と反復体細胞突然変異の次世代シーケンスによる評価2023
- Author(s)
  楠洋一郎、三浦允彦、長村浩子、山岡美佳、久保美子、小山和章、利重匡亮、三角宗近、京泉誠之、佐藤康成、内村有邦、吉田健吾
- Organizer
  第66回日本放射線影響学会年会
- Data Source
  KAKENHI-PROJECT-23K28234
[Presentation] Genome-wide analysis of radiation-induced somatic mutations in mouse long-term hematopoietic stem cells2023
- Author(s)
  Matsuda Y, Uchimura A, Satoh Y, Kato N, Toshishige M, Kume K, Kajimura J, Hamasaki K, Yoshida K, Hayashi T, Noda A, Tanabe O
- Organizer
  73rd Annual Meeting of the American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] X線照射によりマウス造血幹細胞に誘導される体細胞変異の頻度と特徴2022
- Author(s)
  松田由喜子、内村有邦、佐藤康成、加藤直広、利重匡亮、梶村順子、久保美子、山岡美佳、濱崎幹也、吉田健吾、野田朝男、田邉修
- Organizer
  日本放射線影響学会第 65 回大会
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] De novo生殖系列変異の特徴と後世代影響2020
- Author(s)
  内村有邦、佐藤康成、樋口真弓、水口洋平、豊田敦、八木健
- Organizer
  日本遺伝学会第92回大会
- Data Source
  KAKENHI-PROJECT-18K19340
[Presentation] Induced mutations in offspring derived from irradiated mouse spermatogonia and mature oocytes2019
- Author(s)
  Yasunari Satoh, Jun-ichi Asakawa, Mayumi Nishimura, Harry M. Cullings, Yoshiya Shimada, Nori Nakamura, Arikuni Uchimura
- Organizer
  The 16th International Congress of Radiation Research 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19340
[Presentation] De novo germline mutations and their phenotypic effects on future generations2019
- Author(s)
  Arikuni Uchimura, Yasunari Satoh
- Organizer
  第6回アジア環境変異原学会／日本環境変異原学会第48回大会合同大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19340
[Presentation] Mutation spectrum in the genome of offspring derived from irradiated mouse spermatogonia and mature oocytes2019
- Author(s)
  Yasunari Satoh, Mayumi Nishimura, Tony Kuo, Norio Shinkai, Harry M. Cullings, Yohei Minakuchi, Jun Sese, Atsushi Toyoda, Yoshiya Shimada, Nori Nakamura, Arikuni Uchimura
- Organizer
  日本放射線影響学会第62回大会
- Data Source
  KAKENHI-PROJECT-18K19340
[Presentation] A new approach for de novo germline mutations using a mutation accumulation mouse model2019
- Author(s)
  Arikuni Uchimura, Mayumi Higuchi, Yasunari Satoh, Yohei Minakuchi, Takahiro Tsuji, Masaaki Imanaka, Akiko Miura, Atsushi Toyoda, Takeshi Yagi
- Organizer
  日本放射線影響学会第62回大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19340
[Presentation] De novo germline mutations and the phenotypic effects of mutation accumulation in laboratory mice2019
- Author(s)
  Arikuni Uchimura, Yasunari Satoh, Mayumi Higuchi, Yohei Minakuchi, Jo Nishino, Atsushi Toyoda, Takeshi Yagi
- Organizer
  The 16th International Congress of Radiation Research 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19340
[Presentation] マウス生殖系列で発生するde novo変異から見る哺乳類ゲノムの進化2018
- Author(s)
  内村有邦、樋口真弓、水口洋平、松本拡高、若山清香、若山照彦、佐藤康成、福村龍太郎、辻隆弘、今中正明、中本芳子、三浦昭子、権藤洋一、豊田敦、八木健
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05890
[Presentation] マウスモデルを用いた放射線の次世代遺伝影響のゲノムワイド解析2018
- Author(s)
  佐藤康成、Kuo Tony、瀬々潤、西村まゆみ、島田義也、内村有邦
- Organizer
  第43回中国地区放射線影響研究会
- Data Source
  KAKENHI-PROJECT-16H05890
[Presentation] マウスの生殖系列で発生する挿入欠失変異の発生頻度とその特徴2018
- Author(s)
  内村有邦、樋口真弓、水口洋平、佐藤康成、辻隆弘、中本芳子、今中正明、三浦昭子、豊田敦、八木健
- Organizer
  日本放射線影響学会第61回大会
- Data Source
  KAKENHI-PROJECT-18K19340
[Presentation] 精原細胞期と成熟卵母細胞期のマウス生殖細胞への放射線照射は子どものゲノムに小さなサイズの欠失とマルチサイト変異を誘発する2018
- Author(s)
  佐藤康成、Kuo Tony、瀬々潤、西村まゆみ、島田義也、中村典、内村有邦
- Organizer
  日本放射線影響学会第61回大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05890
[Presentation] マウス生殖系列で発生するde novo変異から見る哺乳類ゲノムの進化2018
- Author(s)
  内村有邦、樋口真弓、水口洋平、松本拡高、若山清香、若山照彦、佐藤康成、福村龍太郎、辻隆弘、今中正明、中本芳子、三浦昭子、権藤洋一、豊田敦、八木健
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19340
[Presentation] マウスの生殖系列で発生する挿入欠失変異の発生頻度とその特徴2018
- Author(s)
  内村有邦、樋口真弓、水口洋平、佐藤康成、辻隆弘、中本芳子、今中正明、三浦昭子、豊田敦、八木健
- Organizer
  日本放射線影響学会第61回大会
- Data Source
  KAKENHI-PROJECT-16H05890
[Presentation] 実験室内進化モデルを利用して、哺乳類の進化の過程を理解する2017
- Author(s)
  内村有邦
- Organizer
  第10回Evo-Devo青年の会
- Invited
- Data Source
  KAKENHI-PROJECT-15K12205
[Presentation] 放射線照射されたヒト培養細胞の全ゲノムシーケンス法による塩基置換型突然変異の予備的解析2017
- Author(s)
  佐藤康成、三角宗近、藤本明洋、内村有邦
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-16H05890
[Presentation] 変異蓄積マウス系統を用いた生殖系列変異の解析2017
- Author(s)
  内村有邦、樋口真弓、水口洋平、豊田敦、西野穣、八木健
- Organizer
  第42回中国地区放射線影響研究会
- Data Source
  KAKENHI-PROJECT-16H05890
[Presentation] 日本産野生マウス由来近交系MSM/Msにおける自然突然変異の検出2017
- Author(s)
  福村龍太郎、中井祐治、金相完、森一樹、門田雅世、目加田和之、田代康介、久原哲、吉木淳、豊田敦、藤山秋佐夫、内村有邦、権藤洋一
- Organizer
  日本遺伝学会第89回大会
- Data Source
  KAKENHI-PROJECT-16H05890
[Presentation] 変異蓄積マウス系統は、放射線の遺伝影響を理解するための新たな方法論を提供する2017
- Author(s)
  内村有邦、樋口真弓、水口洋平、福村龍太郎、西野穣、豊田敦、権藤洋一、八木健
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-15K12205
[Presentation] 変異蓄積マウス系統を用いた生殖系列変異の解析2017
- Author(s)
  内村有邦、樋口真弓、水口洋平、豊田敦、西野穣、八木健
- Organizer
  第42回中国地区放射線影響研究会
- Data Source
  KAKENHI-PROJECT-15K12205
[Presentation] 変異蓄積マウス系統は、放射線の遺伝影響を理解するための新たな方法論を提供する2017
- Author(s)
  内村有邦、樋口真弓、水口洋平、福村龍太郎、西野穣、豊田敦、権藤洋一、八木健
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-16H05890
[Presentation] Mutation accumulation experiment with laboratory mice2017
- Author(s)
  Uchimura A,Yagi T
- Organizer
  International Symposium "The start of New Genomics"
- Place of Presentation
  東京大学伊藤国際学術研究センター（東京都文京区）
- Year and Date
  2017-01-10
- Data Source
  KAKENHI-PROJECT-15K14368
[Presentation] 放射線照射されたヒト培養細胞の全ゲノムシーケンス法による塩基置換型突然変異の予備的解析2017
- Author(s)
  佐藤康成、三角宗近、藤本明洋、内村有邦
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-15K12205
[Presentation] Mutation accumulation experiment with laboratory mice2017
- Author(s)
  Arikuni Uchimura
- Organizer
  International Symposium, The Start of New Genomics
- Place of Presentation
  東京大学伊藤国際学術研究センター（東京都文京区）
- Year and Date
  2017-01-10
- Data Source
  KAKENHI-PROJECT-15K12205
[Presentation] 日本産野生マウス由来近交系MSM/Msにおける自然突然変異の検出2017
- Author(s)
  福村龍太郎、中井祐治、金相完、森一樹、門田雅世、目加田和之、田代康介、久原哲、吉木淳、豊田敦、藤山秋佐夫、内村有邦、権藤洋一
- Organizer
  日本遺伝学会第89回大会
- Data Source
  KAKENHI-PROJECT-15K12205
[Presentation] 実験室内進化モデルを利用して、哺乳類の進化の過程を理解する2017
- Author(s)
  内村有邦
- Organizer
  第10回Evo-Devo青年の会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05890
[Presentation] マウスを用いた実験室内進化モデルは、ヒトも含めた哺乳類の進化研究に新たな方法論を提供する2016
- Author(s)
  内村有邦、樋口真弓、水口洋平、豊田敦、藤山秋佐夫、若菜茂晴、西野穣、八木健
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14368
[Presentation] 実験用マウスの生殖系列の突然変異率とその後世代への影響2016
- Author(s)
  内村有邦、樋口真弓、水口洋平、豊田敦、藤山秋佐夫、若菜茂晴、西野穣、八木健
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  ミューザ川崎シンフォニーホール（神奈川県川崎市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K14368
[Presentation] マウスを用いた実験室内進化モデルは、ヒトも含めた哺乳類の進化研究に新たな方法論を提供する2016
- Author(s)
  内村有邦、樋口真弓、水口洋平、豊田敦、藤山秋佐夫、若菜茂晴、西野穣、八木健
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-15K12205
[Presentation] 実験用マウスの生殖系列の突然変異率とその後世代への影響2016
- Author(s)
  内村有邦、樋口真弓、水口洋平、豊田敦、藤山秋佐夫、若菜茂晴、西野穣、八木健
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  ミューザ川崎シンフォニーホール（神奈川県川崎市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K12205
[Presentation] マウス変異蓄積系統を利用した生殖系列の突然変異率の推定とその特徴2015
- Author(s)
  内村有邦、樋口真弓、新見恵理、水口洋平、豊田敦、藤山秋佐夫、西野穣、八木健
- Organizer
  日本遺伝学会第87回大会
- Place of Presentation
  東北大学　（宮城県仙台市）
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-15K12205
[Presentation] Germline mutation rates and mutation accumulation lines in mice2015
- Author(s)
  内村　有邦
- Organizer
  第29回国際哺乳類ゲノム会議
- Place of Presentation
  横浜市開港記念会館（神奈川県横浜市）
- Year and Date
  2015-11-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14368
[Presentation] マウス変異蓄積統計を利用した生殖系列の突然変異率の推定2015
- Author(s)
  内村　有邦
- Organizer
  日本遺伝学会第87回大会
- Place of Presentation
  東北大学川内キャンパス内（宮城県仙台市）
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-15K14368
[Presentation] Germline mutation rates and mutation accumulation lines in mice2015
- Author(s)
  Arikuni Uchimura, Mayumi Higuchi, Yohei Minakuchi, Atsushi Toyoda, Asao Fujiyama, Shigeharu Wakana, Jo Nishino, Takeshi Yagi
- Organizer
  29th International Mammalian Genome Conference
- Place of Presentation
  横浜開港記念館（神奈川県横浜市）
- Year and Date
  2015-11-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12205
[Presentation] DNA replication errors that fuel genetic and phenotypic diversities in mammals2014
- Author(s)
  Arikuni Uchimura
- Organizer
  International Symposium on “Germline Mutagenesis and Biodiversification”
- Place of Presentation
  Kyushu University
- Invited
- Data Source
  KAKENHI-PROJECT-24650235
[Presentation] New genetics by using long-term breeding mutator mouse lines2014
- Author(s)
  Arikuni Uchimura
- Organizer
  RIKEN GSC Tanabata Meeting
- Place of Presentation
  RIKEN Yokohama Campus
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-24650235
[Presentation] Experimental mouse evolution model can produce variable novel phenotypes: the birth of singing mice2013
- Author(s)
  内村有邦
- Organizer
  新学術領域研究「ゲノム支援」国際シンポジウム
- Place of Presentation
  東京大学：伊藤国際学術研究センター
- Data Source
  KAKENHI-PROJECT-23650234
[Presentation] Experimental mouse evolution model can produce variable novel phenotypes: the birth of singing mice2013
- Author(s)
  内村有邦
- Organizer
  新学術領域研究「ゲノム支援」国際シンポジウム
- Place of Presentation
  東京大学:伊藤国際学術研究センター
- Data Source
  KAKENHI-PROJECT-23650234
[Presentation] ヒト可聴音域で発声行動を示す新規変異マウスの解析2012
- Author(s)
  内村有邦
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  九州大学
- Year and Date
  2012-09-26
- Data Source
  KAKENHI-PROJECT-23650234
[Presentation] mutatorマウスの内村有邦長期継代が個体の表現型に及ぼす影響の解析2012
- Author(s)
  内村有邦
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  九州大学
- Year and Date
  2012-09-24
- Data Source
  KAKENHI-PROJECT-23650234
[Presentation] 哺乳類の生殖系列突然変異が後世代の個体に及ぼす影響の解析2012
- Author(s)
  内村有邦
- Organizer
  第25回変異機構研究会夏の学校
- Place of Presentation
  小牧勤労センター
- Data Source
  KAKENHI-PROJECT-23650234
[Presentation] ヒト可聴音域で発声行動を示す新規変異マウスの解析2012
- Author(s)
  八木健、内村有邦、井之上幸範、樋口真弓、日高裕子、涌井菜央、吉岡芳親、石川征司、楯谷一郎、仲川涼子、岡ノ谷一夫、三浦郁生、若菜茂晴
- Organizer
  日本遺伝学会第８４回大会
- Place of Presentation
  九州大学
- Invited
- Data Source
  KAKENHI-PROJECT-24650235
[Presentation] Understanding genetic buffering system in mammalian2012
- Author(s)
  Arikuni Uchimura, Mouse evolution project
- Organizer
  Indo-Japan meeting National Center for Biological Sciences
- Place of Presentation
  Bangalore (India)
- Year and Date
  2012-01-10
- Data Source
  KAKENHI-PROJECT-23650234
[Presentation] マウスをモデルとした、高頻度に発生する生殖系列突然変異が次世代以降の個体に与える影響の解析2011
- Author(s)
  内村有邦、日高裕子、増村健一、能美健彦、三浦郁夫、若菜茂晴、八木健
- Organizer
  日本環境変異原学会第40回大会
- Place of Presentation
  東京
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-23650234
[Presentation] 内因的な突然変異率上昇マウス系統を用いた実験室内進化モデルの試み2010
- Author(s)
  内村有邦
- Organizer
  第57回日本実験動物学会総会
- Place of Presentation
  京都テルサ
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-21657062
[Presentation] 内在的な突然変異率操作による哺乳類進化機構への新たなアプローチ2010
- Author(s)
  内村有邦
- Organizer
  定量生物学の会第二回年会
- Place of Presentation
  大阪大学
- Year and Date
  2010-01-10
- Data Source
  KAKENHI-PROJECT-21657062
[Presentation] 高い突然変異率がもたらす哺乳類集団への影響と新たな表現型の創出2010
- Author(s)
  内村有邦
- Organizer
  第12回日本進化学会大会
- Place of Presentation
  東京工業大学
- Year and Date
  2010-08-03
- Data Source
  KAKENHI-PROJECT-21657062
[Presentation] DNAボリメラーゼδ変異マウスを利用した高い生殖系列突然変異率が後世代に及ぼす影響の解析2010
- Author(s)
  内村有邦
- Organizer
  日本環境変異原学会第39回大会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21657062
[Presentation] 高い突然変異率が哺乳類集団へ及ぼす影響と新たな表現型の創出2010
- Author(s)
  内村有邦
- Organizer
  躰遺伝学会第82回札幌大会
- Place of Presentation
  北海道大学
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21657062
[Presentation] A Effects of a high spontaneous mutation rate in mammalian germline by using mutator mice modified replicative DNA polymerase δ2010
- Author(s)
  内村有邦
- Organizer
  24th International Mammalian Genome Conference
- Place of Presentation
  クレタ(ギリシア)
- Year and Date
  2010-10-19
- Data Source
  KAKENHI-PROJECT-21657062
[Presentation] DNAポリメラーゼδ改変マウス系統を利用した突然変異蓄積の継世代影響2010
- Author(s)
  内村有邦
- Organizer
  変異機構研究会第23回夏の学校
- Place of Presentation
  愛知県小牧勤労センター(招待講演)
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-21657062
[Presentation] 高い突然変異率が哺乳類集団へ及ぼす影響と新たな表現型の創出2010
- Author(s)
  内村有邦
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(招待講演)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21657062
[Presentation] DNA複製エラーを利用した実験室内哺乳類進化実験モデル系の構築2009
- Author(s)
  内村有邦
- Organizer
  第11回日本進化学会大会
- Place of Presentation
  北海道大学
- Year and Date
  2009-09-02
- Data Source
  KAKENHI-PROJECT-21657062
[Presentation] DNAの不連続鎖合成と進化-進化加速の試み-2009
- Author(s)
  内村有邦
- Organizer
  第19回日本熱帯生態学会年次大会
- Place of Presentation
  大阪市立大学
- Year and Date
  2009-06-21
- Data Source
  KAKENHI-PROJECT-21657062
[Presentation] Gene regulatory changes in Protocadherin-a cluster by gene duplication
- Author(s)
  Ryosuke Kaneko, Manabu Abe, Takahiro Hirabayashi, Arikuni Uchimura, Kenji Sakimura, Yuchio Yanagawa, Takeshi Yagi
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650234
[Presentation] mutatorマウスの長期継代が個体の表現型に及ぼす影響の解析
- Author(s)
  内村有邦
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  九州大学
- Invited
- Data Source
  KAKENHI-PROJECT-23650234
[Presentation] A singing strain in mutants from mutator mouse breeding
- Author(s)
  八木健、樋口真弓、水口洋平、豊田敦、藤山秋佐夫、三浦郁生、若菜茂晴、内村有邦
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-10 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24650235
[Presentation] New genetics by using long-term breeding mutator mouse lines
- Author(s)
  Arikuni Uchimura
- Organizer
  理研Genomic Sciences Research Complex (GSC)七夕ミーティング2014
- Place of Presentation
  理化学研究所横浜キャンパス（神奈川県）
- Year and Date
  2014-07-11 – 2014-07-12
- Invited
- Data Source
  KAKENHI-PROJECT-25640047
[Presentation] シンギングマウス(sng変異体)が示す新規ヒト可聴音域発声行動の解析
- Author(s)
  有賀理瑛、井之上幸範、木津川尚史、内村有邦、八木健
- Organizer
  第4回社会神経科学研究会「社会認知とコミュニケーション」
- Place of Presentation
  生理学研究所（愛知県）
- Year and Date
  2014-10-30 – 2014-10-31
- Data Source
  KAKENHI-PROJECT-25640047
[Presentation] 高い突然変異率が後世代の哺乳類集団に及ぼす影響の解析
- Author(s)
  内村有邦、樋口真弓、八木健
- Organizer
  NGS現場の会　第三回研究会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-25640047
[Presentation] DNA replication errors that fuel genetic and phenotypic diversities in mammals
- Author(s)
  Arikuni Uchimura, Mayumi Higuchi, Yohei Minakuchi, Atsushi Toyoda, Asao Fujiyama, Ikuo Miura, Shigeharu Wakana, Takeshi Yagi
- Organizer
  International Symposium on “Germline Mutagenesis and Biodiversification”
- Place of Presentation
  九州大学
- Invited
- Data Source
  KAKENHI-PROJECT-25640047
[Presentation] マウス長期継代系統を用いた生殖系列突然変異率の閾値とその影響
- Author(s)
  内村有邦、樋口真弓、水口洋平、西野穣、豊田敦、藤山秋佐夫、八木健
- Organizer
  日本環境変異原学会　第43回大会
- Place of Presentation
  一橋大学：一橋講堂（東京都）
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-25640047
[Presentation] Mouse evolution project: Understanding genetic buffering system in mammalian
- Author(s)
  Arikuni Uchimura
- Organizer
  Indo-Japan meeting National Center for Biological Sciences
- Place of Presentation
  Bangalore (Indis)
- Data Source
  KAKENHI-PROJECT-23650234
[Presentation] シンギングマウス(sng変異体)が示す新規ヒト可聴音域発声行動の解析
- Author(s)
  有賀理瑛、井之上幸範、木津川尚史、内村有邦、八木健
- Organizer
  第4回社会神経科学研究会「社会認知とコミュニケーション」
- Place of Presentation
  生理学研究所　（愛知県）
- Year and Date
  2014-10-30 – 2014-10-31
- Data Source
  KAKENHI-PROJECT-24650235
[Presentation] マウス長期継代系統を用いた生殖系列突然変異率の閾値とその影響
- Author(s)
  内村有邦、樋口真弓、水口洋平、西野穣、豊田敦、藤山秋佐夫、八木健
- Organizer
  日本環境変異原学会　第43回大会
- Place of Presentation
  一橋講堂　（東京都）
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-24650235
[Presentation] 高い突然変異率が後世代の哺乳類集団に及ぼす影響
- Author(s)
  内村有邦、樋口真弓、豊田敦、藤山秋佐夫、三浦郁生、若菜茂晴、八木健
- Organizer
  日本遺伝学会　第85回大会
- Place of Presentation
  慶応大学　日吉キャンパス
- Data Source
  KAKENHI-PROJECT-25640047
[Presentation] シンギングマウス（sng変異体）が示す新規ヒト可聴音域発声行動
- Author(s)
  有賀理瑛、井之上幸範、木津川尚史、内村有邦、八木健
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-10 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25640047
[Presentation] 長期継代マウス系統を用いた突然変異率の推定と新しい遺伝学
- Author(s)
  内村有邦、樋口真弓、水口洋平、西野穣、豊田敦、藤山秋佐夫、三浦郁生、若菜茂晴、八木健
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  長浜バイオ大学（滋賀県）
- Year and Date
  2014-09-17 – 2014-09-19
- Invited
- Data Source
  KAKENHI-PROJECT-25640047
[Presentation] マウスをモデルとした、高頻度に発生する生殖系列突然変異が次世代以降の個体に与える影響の解析
- Author(s)
  内村有邦、日高裕子、増村健一、能美健彦、三浦郁夫、若菜茂晴、八木健
- Organizer
  日本環境変異原学会　第40回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23650234
[Presentation] Singing mice(sng mutant) exhibited a novel human-audible vocalization behavior
- Author(s)
  有賀理瑛、井之上幸範、木津川尚史、内村有邦、八木健
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-10 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24650235
[Presentation] Mutatorマウスの継代から産まれた「ヒト可聴音域で鳴くマウス」
- Author(s)
  八木健、樋口真弓、水口洋平、豊田敦、藤山秋佐夫、三浦郁生、若菜茂晴、内村有邦
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-10 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25640047
[Presentation] 長期継代マウス系統を用いた突然変異率の推定と新しい遺伝学
- Author(s)
  内村有邦、樋口真弓、水口洋平、西野穣、豊田敦、藤山秋佐夫、三浦郁生、若菜茂晴、八木健
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  長浜バイオ大学　（滋賀県）
- Year and Date
  2014-09-17 – 2014-09-19
- Invited
- Data Source
  KAKENHI-PROJECT-24650235
[Presentation] プロトカドヘリンーaクラスターにおける重複遺伝子の差次的発現
- Author(s)
  金子涼輔、阿部学、平林敬浩、内村有邦、崎村建司、柳川右千夫、八木健
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650234

1. YAGI Takeshi (10241241)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
2. 田邉修 (70221398)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. 松田由喜子 (10735301)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
4. HIGUCHI Mayumi

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
5. 吉田健吾 (70443596)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
6. 権藤洋一 (40225678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 大野みずき (70380524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 松本義久 (20302672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 楠洋一郎 (60333548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 濱崎幹也 (80443597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. TSUKANO Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 渋木克栄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 菱田竜一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 柳川右千夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 木村実

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 阿部修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 青木茂樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 崎村建司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Uchimura Arikuni 内村 有邦

UCHIMURA Arikuni 内村 有邦

内村 有邦 ウチムラ アリクニ

Research Projects

Research Products

Co-Researchers

Risk assessment of next-generation effects based on Whole Genome Sequencing at the T2T LevelPrincipal Investigator

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Analysis of changes in radiation-induced mutational signatures induced by DNA repair inhibitors and their impact on carcinogenic risk.

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Mechanisms of next generation inheritance of genomic information including hypervariable mega-genomic regionsPrincipal Investigator

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High-throughput and precision analysis of biological effects of low-dose-rate radiation.

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Time-resolved biodosimetry based on clonal hematopoiesis and somatic mutations in atomic-bomb survivors

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Whole-genome sequence analysis of radiation-induced mutations in human hematopoietic stem cells

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Cell lineage analysis by using post-zygotic spontaneous mutationsPrincipal Investigator

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Single molecular analysis of germline mutagenesis and risk assessment for future generationPrincipal Investigator

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In vivo genotoxicity test focusing on mosaic mutations in germline cellsPrincipal Investigator

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A life design model using mutator mice

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Novel animal model by using high germline mutation rate

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New mouse model for an aural communicationPrincipal Investigator

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Production of new design mice by accumulation of mutations

Principal Investigator

Uchimura Arikuni 内村有邦

UCHIMURA Arikuni 内村有邦

内村有邦ウチムラアリクニ