Iizumi Yosuke 飯泉陽介

… Alternative Names

IIZUMI Yosuke 飯泉陽介

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Researcher Number	20533178
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Affiliation (based on the past Project Information) *help	2011 – 2023: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2012: 京都府立医科大学, 大学院・医学研究科, 助教 2009 – 2011: Kyoto Prefectural University of Medicine, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Hygiene / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Hygiene and public health Except Principal Investigator Complex systems / Hygiene and public health
Keywords	Principal Investigator ナノ磁性ビーズ / ケミカルバイオロジー / がん予防 / 結合タンパク質 / 食品成分 / 作用機序 / 癌予防 / メトホルミン / 糖新生 / β-catenin … More / 結合蛋白 / 標的分子 / がん予防効果 / mTORC1 / AMPK / 結合タンパク質B / 結合タンパク質A / Wnt経路 / 大腸がん / 糖新生抑制タンパク質 / 標的タンパク質 / 化学予防 / 大腸癌 / 遺伝子変異 / 天然由来化合物 / スクリーニング / 天然化合物 / APOBEC3B / NF-kappaB / 質量分析計 / 新規メカニズム / 質量分析 / 細胞死 / 細胞周期 / Akt / p21 / プロテオミクス / アピゲニン / フラボノイド … More Except Principal Investigator 天然物 / がん予防 / Eomes / T-bet / IL-6 / 細胞老化 / NK細胞 / ケミカルバイオロジー / スクリーニング / SASP / 分子予防 / 抗酸化能 / 飲料 / 抗炎症 / 抗酸化 / RB再活性化 / 分子標的予防法 Less

Mechanistic elucidation of chemopreventive effects of metformin through analyzing novel identified metformin-binding proteinsPrincipal Investigator
- Principal Investigator
  
  IIZUMI Yosuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kyoto Prefectural University of Medicine
Detailed analysis of the molecular basis for cancer chemoprevention with metforminPrincipal Investigator
- Principal Investigator
  
  Iizumi Yosuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kyoto Prefectural University of Medicine
Research of molecular-targeting prevention against inflammatory diseases using chemical biology.
- Principal Investigator
  
  Sakai Toshiyuki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto Prefectural University of Medicine
Development of the cancer preventive strategy against a newly identified risk factorPrincipal Investigator
- Principal Investigator
  
  Iizumi Yosuke
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene and public health
- Research Institution
  Kyoto Prefectural University of Medicine
Application of molecular-targeting cancer prevention to human intervention study.
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hygiene and public health
- Research Institution
  Kyoto Prefectural University of Medicine
Identification of the cancer preventive targets useful foractivating the tumor suppressive gene p21Principal Investigator
- Principal Investigator
  
  IIZUMI Yosuke
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Comprehensive identification of cancer chemopreventive target molecules by Chemical Biology and the tailor-made prevention of cancerPrincipal Investigator
- Principal Investigator
  
  IIZUMI Yosuke
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Identification of flavonoids-binding proteins, and basic research of cancer prevention based on molecular mechanismsPrincipal Investigator
- Principal Investigator
  
  IIZUMI Yosuke
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine

All 2022 2021 2020 2019 2018 2017 2015 2014 2013 2011 2010 Other

All Journal Article Presentation Book

[Book] Colloids in Biotechnology(Affinity Magnetic Beads for Chemical Biology and Medicine)Chapter 92011
- Author(s)
  Yosuke Iizumi, Yasuaki Kabe, Mamoru Hatakeyama, Satoshi Sakamoto, Hiroshi Handa
- Publisher
  Monzer Fanun CRC
- Data Source
  KAKENHI-PROJECT-21890223
[Journal Article] Stabilization of CDK6 by ribosomal protein uS7, a target protein of the natural product fucoxanthinol2022
- Author(s)
  Iizumi Y, Sowa Y, Goi W, Aono Y, Watanabe M, Kurumida Y, Kameda T, Akaji K, Kitagawa M, Sakai T.
- Journal Title
  
  Communications Biology
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] Oridonin inhibits SASP by blocking p38 and NF-κB pathways in senescent cells2022
- Author(s)
  Yasuda Shusuke、Horinaka Mano、Iizumi Yosuke、Goi Wakana、Sukeno Mamiko、Sakai Toshiyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 590 Pages: 55-62
- DOI
  10.1016/j.bbrc.2021.12.098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] A chemoproteoinformatics approach demonstrates that aspirin increases sensitivity to MEK inhibition by directly binding to RPS52022
- Author(s)
  Watanabe M, Boku S, Kobayashi K, Kurumida Y, Sukeno M, Masuda M, Mizushima K, Kato C, Iizumi Y, Hirota K, Naito Y, Mutoh M, Kameda T, Sakai T
- Journal Title
  
  PNAS Nexus
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] Sodium salicylate and 5-aminosalicylic acid synergistically inhibit the growth of human colon cancer cells and mouse intestinal polyp-derived cells2022
- Author(s)
  Takakura H, Horinaka M, Imai A, Aono Y, Nakao T, Miyamoto S, Iizumi Y, Watanabe M, Narita T, Ishikawa H, Mutoh M, Sakai T
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 70 Issue: 2 Pages: 93-102
- DOI
  10.3164/jcbn.21-74
- NAID
  130008165971
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889
[Journal Article] Rabdosianone I, a Bitter Diterpene from an Oriental Herb, Suppresses Thymidylate Synthase Expression by Directly Binding to ANT2 and PHB22021
- Author(s)
  Watanabe M, Yamada Y, Kurumida Y, Kameda T, Sukeno M, Iizuka-Ohashi M, Sowa Y, Iizumi Y, Takakura H, Miyamoto S, Sakai T, Mutoh M.
- Journal Title
  
  Cancers.
  
  Volume: 13 Issue: 5 Pages: 982-982
- DOI
  10.3390/cancers13050982
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079
[Journal Article] Artesunate Inhibits Intestinal Tumorigenesis through Inhibiting Wnt Signaling.2020
- Author(s)
  Hamoya T, Fujii G, Iizumi Y, Narita T, Komiya M, Matsuzawa Y, Miki K, Kondo T, Kishimoto S, Watanabe K, Wakabayashi K, Sakai T, Toshima J, Mutoh M
- Journal Title
  
  Carcinogenesis
  
  Volume: 42 Issue: 1 Pages: 148-58
- DOI
  10.1093/carcin/bgaa084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11066, KAKENHI-PROJECT-19K06571, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H02898, KAKENHI-PROJECT-19J10184
[Journal Article] Synergistic effect of the inhibitors of RAF/MEK and AXL on KRAS-mutated ovarian cancer cells with high AXL expression.2020
- Author(s)
  Umemura S, Sowa Y, Iizumi Y, Kitawaki J, Sakai T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 111 Issue: 6 Pages: 2052-2061
- DOI
  10.1111/cas.14414
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-18K09295
[Journal Article] Histone deacetylase inhibitor OBP-801 and amrubicin synergistically inhibit the growth of squamous cell lung carcinoma by inducing mitochondrial ASK1-dependent apoptosis.2020
- Author(s)
  Chihara Y, Iizumi Y, Horinaka M, Watanabe M, Goi W, Morita M, Nishimoto E, Sowa Y, Yamada T, Takayama K, Sakai T.
- Journal Title
  
  Int J Oncol.
  
  Volume: 56 Pages: 848-856
- DOI
  10.3892/ijo.2020.4969
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-19K22773
[Journal Article] Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 2.2018
- Author(s)
  Aono Y, Horinaka M, Iizumi Y, Watanabe M, Taniguchi T, Yasuda S, Sakai T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 505 Pages: 1203-1210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02529
[Journal Article] Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 22018
- Author(s)
  Aono Yuichi、Horinaka Mano、Iizumi Yosuke、Watanabe Motoki、Taniguchi Tomoyuki、Yasuda Shusuke、Sakai Toshiyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 505 Issue: 4 Pages: 1203-1210
- DOI
  10.1016/j.bbrc.2018.10.050
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-16H05260, KAKENHI-PROJECT-17K19829
[Journal Article] Ribosomal protein S3 regulates XIAP expression independently of the NF-κB pathway in breast cancer cells2017
- Author(s)
  Ono H, Iizumi Y, Goi W, Sowa Y, Taguchi T, Sakai T
- Journal Title
  
  Oncol Rep
  
  Volume: 38 Issue: 5 Pages: 3205-3210
- DOI
  10.3892/or.2017.6008
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06398
[Journal Article] The flavonoid apigenin downregulates CDK1 by directly targeting ribosomal protein S92013
- Author(s)
  Iizumi Y, Oishi M, Taniguchi T, Goi W, Sowa Y, Sakai T
- Journal Title
  
  PLoS One.
  
  Volume: 8(8) Issue: 8 Pages: e73219-e73219
- DOI
  10.1371/journal.pone.0073219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10279, KAKENHI-PROJECT-23689036
[Journal Article] Apigenin sensitizes prostate cancer cells to Apo2L/TRAIL by targeting adenine nucleotide translocase-22013
- Author(s)
  Oishi M, Iizumi Y, Taniguchi T, Goi W, Miki T, Sakai T
- Journal Title
  
  PLoS One
  
  Volume: Vol. 8、 No. 2 Issue: 2 Pages: e55922-e55922
- DOI
  10.1371/journal.pone.0055922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042, KAKENHI-PROJECT-23659335, KAKENHI-PROJECT-23689036
[Journal Article] Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway.2010
- Author(s)
  Kanako Kume, Yosuke Iizumi, Masashi Shimada, Yuki Ito, Tsutomu Kishi, Yuki Yamaguchi, Hiroshi Handa
- Journal Title
  
  Genes to Cells 15(4)
  
  Pages: 339-349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890223
[Presentation] 延命草成分オリドニンはp38とNF-κBを介して老化関連分泌現象を阻害する2022
- Author(s)
  安田周祐, 堀中真野, 飯泉陽介, 後居和佳奈, 助野真美子, 酒井敏行
- Organizer
  第21回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] PIK3CA変異大腸癌細胞においてグルタミン代謝阻害がアスピリンに対する感受性を促進する2021
- Author(s)
  朴将源, 渡邉元樹, 飯塚まひろ, 曽和義広, 増田光治, 飯泉陽介, 成田匠, 佐竹悠良, 酒井敏行, 武藤倫弘
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 細胞外グルタミン濃度はがん予防薬の感受性に影響する2021
- Author(s)
  渡邉元樹, 朴将源, 宮本景子, 曽和義広, 飯泉陽介, 増田光治, 成田匠, 中尾俊雅, 武藤倫弘, 酒井敏行
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] xCT inhibition increases sensitivity to vorinostat in a ROS-dependent manner.2020
- Author(s)
  渡邉元樹, 宮本景子, 朴将源, 阪口晃一, 田口哲也, 曽和義広, 飯泉陽介, 増田光治, 成田匠, 鱧屋隆博, 酒井敏行, 武藤倫弘
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] Synergistic effect of the inhibitors of RAF/MEK and AXL on KRAS-mutated ovarian cancer cells with high AXL expression.2020
- Author(s)
  楳村史織, 曽和義広, 飯泉陽介, 酒井敏行
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 新規スリンダクスルホン結合タンパク質VDACによる細胞周期制御のメカニズムの解析2019
- Author(s)
  青野裕一，堀中真野，飯泉陽介，渡邉元樹，谷口知行，安田周祐，酒井敏行
- Organizer
  第18回分子予防環境医学研究会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] スリンダク代謝体の大腸腺腫形成抑制作用における新規標的分子の探索と作用機序の解析2019
- Author(s)
  青野裕一，堀中真野，飯泉陽介，渡邉元樹，谷口知行，安田周祐，酒井敏行
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] セサミノール結合タンパク質ANT2の発見がもたらす新たな細胞周期調節機構の解明2018
- Author(s)
  渡邉元樹、飯泉陽介、助野真美子、曽和義広、酒井敏行
- Organizer
  第88回　日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] クルクミンによるがん予防効果の分子機構解明の試み2018
- Author(s)
  飯泉陽介、小野寿子、後居和佳奈、曽和義広、酒井敏行
- Organizer
  第88回　日本衛生学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] 新規セサミノール結合蛋白質ANT2によるcyclin D1の多面的制御機構の解明2018
- Author(s)
  渡邉元樹、飯泉陽介、曽和義広、酒井敏行
- Organizer
  第２２回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] セサミノール結合タンパク質ANT2の発見がもたらすcyclin D1の多面的制御機構の解明2018
- Author(s)
  渡邉元樹、飯泉陽介、助野真由美、曽和義広、酒井敏行
- Organizer
  第１７回分子予防環境医学研究会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] クルクミンによるがん予防効果の分子機構の解析2018
- Author(s)
  飯泉陽介、小野寿子、後居和佳奈、曽和義広、酒井敏行
- Organizer
  第17回　分子予防環境医学研究会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] セサミノール結合タンパク質ANT2の発見がもたらすcyclin D1の多面的制御機構の解明2018
- Author(s)
  渡邉元樹、飯泉陽介、助野真美子、曽和義広、酒井敏行
- Organizer
  第17回　分子予防環境医学研究会
- Data Source
  KAKENHI-PLANNED-17H06398
[Presentation] セサミノール結合タンパク質ANT2の発見がもたらす新たな細胞周期調節機構の解明2018
- Author(s)
  渡邉元樹、飯泉陽介、助野真由美、曽和義広、酒井敏行
- Organizer
  第８８回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] The strategy of molecular-targeting cancer prevention (がんの分子標的予防戦略)2017
- Author(s)
  堀中真野, 飯泉陽介, 渡邉元樹, 増田光治, 曽和義広, 酒井敏行
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] がん分子標的予防の実現に向けて2015
- Author(s)
  飯泉陽介　他
- Organizer
  日本衛生学会
- Place of Presentation
  和歌山県民文化会館
- Year and Date
  2015-03-27
- Invited
- Data Source
  KAKENHI-PROJECT-23689036
[Presentation] ポリフェノール結合タンパク質の比較によるアピゲニンのTRAIL感受性増強機構の解明2014
- Author(s)
  飯泉陽介　他
- Organizer
  日本衛生学会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2014-05-26
- Data Source
  KAKENHI-PROJECT-23689036
[Presentation] ポリフェノール結合タンパク質同定法の開発と細胞周期制御機構の解析2014
- Author(s)
  飯泉陽介　他
- Organizer
  日本癌学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-23689036
[Presentation] ポリフェノール標的タンパク質同定法の開発と作用機序解明2014
- Author(s)
  飯泉陽介　他
- Organizer
  日本がん分子標的治療学会
- Place of Presentation
  TKPガーデンシティ仙台
- Year and Date
  2014-06-26
- Data Source
  KAKENHI-PROJECT-23689036
[Presentation] ケミカルバイオロジーを用いたポリフェノール標的タンパク質の同定法2014
- Author(s)
  飯泉陽介　他
- Organizer
  日本がん予防学会
- Place of Presentation
  国立がん研究センター築地キャンパス
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-23689036
[Presentation] ポリフェノール標的タンパク質の同定法とその応用2014
- Author(s)
  飯泉陽介　他
- Organizer
  日本衛生学会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2014-05-26
- Data Source
  KAKENHI-PROJECT-23689036
[Presentation] ケミカルバイオロジーを活用した抗癌剤開発と癌予防研究2011
- Author(s)
  飯泉陽介、後居和佳奈、谷口知行、大石正勝、曽和義広、酒井敏行
- Organizer
  日本ケミカルバイオロジー学会
- Place of Presentation
  東京工業大学大岡山キャンパス
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-23689036
[Presentation] ポリフェノール結合タンパク質の同定と比較による、アピゲニンの抗腫瘍性サイトカインTRAIL 感受性増強機構の解明
- Author(s)
  飯泉陽介　他
- Organizer
  日本がん分子標的治療学会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23689036
[Presentation] ケミカルバイオロジーを活用した抗癌剤開発と癌予防研究
- Author(s)
  飯泉　陽介、後居和佳奈、谷口知行、大石正勝、曽和義広、酒井敏行
- Organizer
  日本ケミカルバイオロジー学会
- Place of Presentation
  東京工業大学　大岡山キャンパス
- Data Source
  KAKENHI-PROJECT-23659335
[Presentation] ポリフェノール結合タンパク質の同定と比較によるアピゲニンのTRAIL感受性増強機構の解明
- Author(s)
  飯泉陽介　他
- Organizer
  日本がん予防学会
- Place of Presentation
  日本薬学会長井記念館
- Data Source
  KAKENHI-PROJECT-23689036
[Presentation] ポリフェノール標的タンパク質の同定法の開発
- Author(s)
  飯泉陽介　他
- Organizer
  分子予防環境医学研究会
- Place of Presentation
  和歌山県民文化会館
- Data Source
  KAKENHI-PROJECT-23689036

1. SAKAI Toshiyuki (20186993)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
2. 友杉真野 (80512037)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. 増田光治 (10305568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 曽和義広 (70315935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 渡邉元樹 (40723581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. 石川秀樹 (30351795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 早川芳弘 (10541956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 安田周祐 (10643398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. Imai Ayaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Goi Wakana

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 藤井元

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Iizumi Yosuke 飯泉 陽介

IIZUMI Yosuke 飯泉 陽介

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Mechanistic elucidation of chemopreventive effects of metformin through analyzing novel identified metformin-binding proteinsPrincipal Investigator

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Detailed analysis of the molecular basis for cancer chemoprevention with metforminPrincipal Investigator

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Research of molecular-targeting prevention against inflammatory diseases using chemical biology.

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Development of the cancer preventive strategy against a newly identified risk factorPrincipal Investigator

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Application of molecular-targeting cancer prevention to human intervention study.

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Identification of the cancer preventive targets useful foractivating the tumor suppressive gene p21Principal Investigator

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Comprehensive identification of cancer chemopreventive target molecules by Chemical Biology and the tailor-made prevention of cancerPrincipal Investigator

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Identification of flavonoids-binding proteins, and basic research of cancer prevention based on molecular mechanismsPrincipal Investigator

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[Book] Colloids in Biotechnology(Affinity Magnetic Beads for Chemical Biology and Medicine)Chapter 92011

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[Journal Article] Stabilization of CDK6 by ribosomal protein uS7, a target protein of the natural product fucoxanthinol2022

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[Journal Article] Oridonin inhibits SASP by blocking p38 and NF-κB pathways in senescent cells2022

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[Journal Article] A chemoproteoinformatics approach demonstrates that aspirin increases sensitivity to MEK inhibition by directly binding to RPS52022

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[Journal Article] Sodium salicylate and 5-aminosalicylic acid synergistically inhibit the growth of human colon cancer cells and mouse intestinal polyp-derived cells2022

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[Journal Article] Rabdosianone I, a Bitter Diterpene from an Oriental Herb, Suppresses Thymidylate Synthase Expression by Directly Binding to ANT2 and PHB22021

Author(s)

Iizumi Yosuke 飯泉陽介

IIZUMI Yosuke 飯泉陽介