Kimura Akihiro 木村彰宏

… Alternative Names

KIMURA Akihiro 木村彰宏

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Researcher Number	20533318
Other IDs
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立国際医療研究所肝炎・免疫研究センター, 室長
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人国立国際医療研究センター, その他部局等, 室長 2017 – 2023: 国立研究開発法人国立国際医療研究センター, その他部局等, 室長 2017: 慶應義塾大学, 医学部, 助教 2014: 独立行政法人国立国際医療研究センター, その他部局等, その他 2010 – 2013: Keio University, 医学部, 助教 2009: Osaka University, 大学院・生命機能研究科, 寄附講座助教
Review Section/Research Field	Principal Investigator Immunology / Basic Section 49070:Immunology-related Except Principal Investigator Basic Section 49070:Immunology-related / Immunology
Keywords	Principal Investigator IL-6 / マクロファージ / LPS / NQO1 / Th17細胞 / Th17 / 活性酸素 / リステリア / ダイオキシン受容体 / 自然免疫 … More / IL-10 / 酸化ストレス / 多発性硬化症 / NAD( P)H：キノン酸化還元酵素 1 / PDLIM2 / Treg細胞 / アルカロイド / Treg / ハルミン / リステリオリジン O / AIM / listeria monocytogenes / 関節リウマチ / Ahr … More Except Principal Investigator 自然免疫 / マクロファージ / 炎症 / 慢性炎症 / 自己免疫疾患 / 炎症性サイトカイン / シトルリン化 / アラーミン / 関節リウマチ / チロシンキナーゼ / インフラマゾーム / 細菌 / 生体恒常性 / T細胞 / 組織傷害 / TGFβ / アレルギー・ぜんそく / 免疫学 / レチノイン酸受容体 / 転写因子 / スカベンジャー受容体 / 修復機構 / 組織損傷 / 脳梗塞 / 修復 / 組織障害 / 制御性T細胞 / シグナル伝達 / サイトカイン Less

細胞外アミノアシルtRNA合成酵素による炎症老化に伴う自己免疫疾患発症機構の解明Principal Investigator
- Principal Investigator
  
  木村彰宏
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  National Center for Global Health and Medicine
Development of MS therapy targeting Nqo1Principal Investigator
- Principal Investigator
  
  Kimura Akihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  National Center for Global Health and Medicine
Effect of novel alarmin on pathogenesis of Rheumatoid Arthrits
- Principal Investigator
  
  Suzuki Harumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  National Center for Global Health and Medicine
Regulation of innate immune responses by NQO1-PDLIM2 axisPrincipal Investigator
- Principal Investigator
  
  Kimura Akihiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  National Center for Global Health and Medicine
Harmine regulates immune responsesPrincipal Investigator
- Principal Investigator
  
  KIMURA Akihiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Research Institute, International Medical Center of Japan
  Keio University
Identification of Cellular Signaling Mechanism that regulates inflammation and tissue repairing
- Principal Investigator
  
  YOSHIMURA Akihiko
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Immunology
- Research Institution
  Keio University
AhR regulates innate immune responses and Th17 cell differentiationPrincipal Investigator
- Principal Investigator
  
  KIMURA Akihiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Keio University
Aryl hydrocarbon receptor regulates innate and acquired immune resposesPrincipal Investigator
- Principal Investigator
  
  KIMURA Akihiro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Keio University
  Osaka University

All 2024 2023 2022 2019 2018 2017 2015 2014 2013 2012 2011 2010 2009

All Journal Article Presentation Book Patent

[Book] Th17細胞の分化とIL-6の役割. 臨床免疫・アレルギー科、592013
- Author(s)
  木村彰宏
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-23790545
[Book] Aryl hydrocarbon receptor/IDO産生樹状細胞によるレギュラトリーT細胞の誘導. 臨床免疫・アレルギー科、572012
- Author(s)
  木村彰宏
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-23790545
[Book] Aryl hydrocarbon receptorによる免疫応答制御機構(臨床免疫・アレルギー科55)2011
- Author(s)
  木村彰宏
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-21790468
[Book] Aryl hydrocarbon receptorによるLPS応答の制御(臨床免疫・アレルギー科53)2010
- Author(s)
  木村彰宏、岸本忠三
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-21790468
[Book] Th17細胞とダイオキシンレセプター(感染・炎症・免疫39)2009
- Author(s)
  木村彰宏、仲哲治、岸本忠三
- Publisher
  医薬の門社
- Data Source
  KAKENHI-PROJECT-21790468
[Book] 感染・炎症・免疫2009
- Author(s)
  木村彰宏
- Publisher
  医薬の門社
- Data Source
  KAKENHI-PROJECT-21790468
[Book] Th17細胞の分化とaryl hydrocarbon receptor(臨床免疫・アレルギー科52)2009
- Author(s)
  木村彰宏、岸本忠三
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-21790468
[Book] Th17と関節炎(炎症と免疫17)2009
- Author(s)
  木村彰宏、仲哲治、岸本忠三
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-21790468
[Book] 炎症と免疫2009
- Author(s)
  木村彰宏
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-21790468
[Journal Article] Extracellular aaRSs drive autoimmune and inflammatory responses in rheumatoid arthritis via the release of cytokines and PAD42023
- Author(s)
  Kimura A, Takagi T, Thamamongood T, Sakamoto S, Ito T, Seki I, Okamoto M, Aono H, Serada S, Naka T, Imataka H, Miyake K, Ueda T, Miyanokoshi M, Wakasugi K, Iwamoto N, Ohmagari N, Iguchi T, Nitta T, Takayanagi H, Yamashita H, Kaneko H, Tsuchiya H, Fujio K, Handa H, Suzuki H.
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 82 Issue: 9 Pages: 1153-1161
- DOI
  10.1136/ard-2023-224055
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KJ1021, KAKENHI-PROJECT-23K06590, KAKENHI-PROJECT-21K07088, KAKENHI-PROJECT-21K18254, KAKENHI-PROJECT-22K19424, KAKENHI-PLANNED-22H05184, KAKENHI-PUBLICLY-22H05559, KAKENHI-PUBLICLY-23H04770, KAKENHI-PROJECT-21H05046, KAKENHI-PROJECT-21H04800, KAKENHI-PROJECT-23K23875, KAKENHI-PROJECT-23K24148
[Journal Article] Antioxidative enzyme NAD(P)H quinone oxidoreductase 1 (NQO1) modulates the differentiation of Th17 cells by regulating ROS levels2022
- Author(s)
  Nishida-Tamehiro Kyoko、Kimura Akihiro、Tsubata Takeshi、Takahashi Satoru、Suzuki Harumi
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 7 Pages: e0272090-e0272090
- DOI
  10.1371/journal.pone.0272090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07088, KAKENHI-PROJECT-21H02679
[Journal Article] Immunomodulatory mechanism of acyclic nucleoside phosphates in treatment of hepatitis B virus infection.2019
- Author(s)
  Murata K, Tsukuda S, Suizu F, Kimura A, Sugiyama M, Watashi K, Noguchi M, Mizokami M.
- Journal Title
  
  Hepatology
  
  Volume: 71 Issue: 5 Pages: 1533-1545
- DOI
  10.1002/hep.30956
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08896, KAKENHI-PROJECT-17K09448, KAKENHI-PROJECT-17H04085
[Journal Article] Cutting Edge: Nqo1 Regulates Irritant Contact Hypersensitivity against Croton Oil through Maintenance of Dendritic Epidermal T Cells2018
- Author(s)
  Kitajima Masayuki、Kimura Akihiro、Suzuki Harumi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 200 Issue: 5 Pages: 1555-1559
- DOI
  10.4049/jimmunol.1701389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08803, KAKENHI-PROJECT-17K08896
[Journal Article] NQO1 inhibits the TLR-dependent production of selective cytokines by promoting IκB-ζ degradation.2018
- Author(s)
  1. Kimura, A., Kitajima, M., Nishida, K., Serada, S., Fujimoto, M., Naka, T., Fuji-Kuriyama, Y., Ito, T., Handa, H., Tanaka, T, Yoshimura, A., Suzuki, H.
- Journal Title
  
  Journal of experimental medicine
  
  Volume: 215 Issue: 8 Pages: 2197-2200
- DOI
  10.1084/jem.20172024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08803, KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-17H04213, KAKENHI-PROJECT-17K08896
[Journal Article] ETS transcription factor ETV2 directly converts human fibroblasts into functional endothelial cells.2015
- Author(s)
  Morita R, Suzuki M, Kasahara H, Shimizu N, Shichita T, Sekiya T, Kimura A, Sasaki K, Yasukawa H, Yoshimura A.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 112 Issue: 1 Pages: 160-165
- DOI
  10.1073/pnas.1413234112
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25221305, KAKENHI-PROJECT-25670233, KAKENHI-PROJECT-25670234, KAKENHI-PROJECT-26713019, KAKENHI-PROJECT-26461137, KAKENHI-PROJECT-26670470
[Journal Article] Aryl hydrocarbon receptor protects against bacterial infection by promoting macrophage survival and reactive oxygen species production2014
- Author(s)
  Kimura A, Abe H, Tsuruta S, Chiba S, Fujii-Kuriyama Y, Sekiya T, Morita R, Yoshimura A.
- Journal Title
  
  Int Immunol.
  
  Volume: 26 Issue: 4 Pages: 209-220
- DOI
  10.1093/intimm/dxt067
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24117718, KAKENHI-PROJECT-25670233, KAKENHI-PROJECT-25670234, KAKENHI-PROJECT-25860324, KAKENHI-PROJECT-26713019, KAKENHI-PROJECT-25221305
[Journal Article] Aryl hydrocarbon receptor plays protective roles in ConA-induced hepatic injury by both suppressing IFN-Y expression and inducing IL-222014
- Author(s)
  Abe H, Kimura A, Tsuruta S, Fukaya T, Sakaguchi R, et al.
- Journal Title
  
  Int Immunol.
  
  Volume: 26 Issue: 3 Pages: 129-137
- DOI
  10.1093/intimm/dxt049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J08459, KAKENHI-PUBLICLY-24117718, KAKENHI-PROJECT-25670233, KAKENHI-PROJECT-25670234, KAKENHI-PROJECT-26670383, KAKENHI-PROJECT-25221305
[Journal Article] Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis.2013
- Author(s)
  Sekiya T, Kashiwagi I, Yoshida R, Fukaya T, et al.
- Journal Title
  
  Nat Immunol.
  
  Volume: 14 Issue: 3 Pages: 230-237
- DOI
  10.1038/ni.2520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08459, KAKENHI-PROJECT-21500305, KAKENHI-PROJECT-22249009, KAKENHI-PROJECT-22590438, KAKENHI-PROJECT-23659242, KAKENHI-PROJECT-23790346, KAKENHI-PROJECT-23790545, KAKENHI-PROJECT-25670233
[Journal Article] IL-23-Independent Induction of IL-17 from γδT Cells and Innate Lymphoid Cells Promotes Experimental Intraocular Neovascularization2013
- Author(s)
  Hasegawa E
- Journal Title
  
  J Immunol
  
  Volume: 190 Issue: 4 Pages: 1778-1787
- DOI
  10.4049/jimmunol.1202495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249009, KAKENHI-PROJECT-22590438, KAKENHI-PROJECT-23592573, KAKENHI-PROJECT-23689071, KAKENHI-PROJECT-23790545, KAKENHI-PROJECT-24890232, KAKENHI-PROJECT-25670233
[Journal Article] Forced expression of stabilized c-Fos in dendritic cells reduces cytokine production and immune responses in vivo.2012
- Author(s)
  Yoshida R
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 423 Issue: 2 Pages: 247-252
- DOI
  10.1016/j.bbrc.2012.05.097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659242, KAKENHI-PROJECT-23790545, KAKENHI-PROJECT-25670233
[Journal Article] Low dose CP-690,550 (tofacitinib), a pan-JAK inhibitor, accelerates the onset of experimental autoimmune encephalomyelitis by potentiating Th17 differentiation2012
- Author(s)
  Yoshida H, Kimura A, Fukaya T, Sekiya T, Morita R, Shichita T, Inoue H, Yoshimura A
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 418 Pages: 234-240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790545
[Journal Article] Low dose CP-690,550 (tofacitinib), a pan-JAK inhibitor, accelerates the onset of experimental autoimmune encephalomyelitis by potentiating Th17 differentiation.2012
- Author(s)
  Yoshida H, Kimura A, Fukaya T, Sekiya T, Morita R, Shichita T, Inoue H, Yoshimura A
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 418 Pages: 234-240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790545
[Journal Article] Smad2 and Smad3 are redundantly essential for the suppression of iNOS synthesis in macrophages by regulating IRF3 and STAT1 pathways2012
- Author(s)
  Sugiyama Yuki, 他
- Journal Title
  
  International Immunology
  
  Volume: 24 Issue: 4 Pages: 253-256
- DOI
  10.1093/intimm/dxr126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J04955, KAKENHI-PROJECT-22590438, KAKENHI-PROJECT-23591356, KAKENHI-PROJECT-23790545, KAKENHI-PROJECT-23791662, KAKENHI-PUBLICLY-24117718
[Journal Article] Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain2012
- Author(s)
  Shichita T
- Journal Title
  
  Nature Medicine
  
  Volume: 18 Issue: 6 Pages: 911-917
- DOI
  10.1038/nm.2749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249009, KAKENHI-PROJECT-22590420, KAKENHI-PROJECT-23591262, KAKENHI-PROJECT-23659242, KAKENHI-PROJECT-23659687, KAKENHI-PROJECT-23790545, KAKENHI-PROJECT-23791662, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590337, KAKENHI-PLANNED-21117002, KAKENHI-PUBLICLY-24117718
[Journal Article] SOCS1 regulates type I/type II NKT cell balance by regulating IFNgamma signaling.2011
- Author(s)
  Hashimoto M, Hiwatashi K, Ichiyama K, Morita R, Sekiya T, Kimura A, Sugiyama Y, Sibata T, Kuroda K, Takahashi R, Yoshimura A.
- Journal Title
  
  Int Immunol 23
  
  Pages: 165-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790468
[Journal Article] SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-{gamma} and IL-17A production.2011
- Author(s)
  Takahashi R, Nishimoto S, Muto G, Sekiya T, Tamiya T, Kimura A, Morita R, Asakawa M, Chinen T, Yoshimura A.
- Journal Title
  
  J Exp Med.
  
  Volume: 208 Issue: 10 Pages: 2055-2067
- DOI
  10.1084/jem.20110428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590438, KAKENHI-PROJECT-23790545, KAKENHI-PROJECT-23791121
[Journal Article] Aryl hydrocarbon receptor negatively regulates LPS-induced IL-6 production through suppression of histamine production in macrophages2011
- Author(s)
  Masuda K, Kimura A, Hanieh H, Nguyen NT, Nakahama T, Chinen I, Otoyo Y, Murotani T, Yamatodani A, Kishimoto T.
- Journal Title
  
  Int Immunol
  
  Volume: 23 Issue: 10 Pages: 637-645
- DOI
  10.1093/intimm/dxr072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790545
[Journal Article] Suppression of SOCS3 in macrophages prevents cancer metastasis by modifying macrophage phase and MCP2/CCL8 induction2011
- Author(s)
  Hiwatashi K, Tamiya T, Hasegawa E, Fukaya T, Hashimoto M, Kakoi K, Kashiwagi I, Kimura A, Inoue N, Morita R, Yasukawa H, Yoshimura A
- Journal Title
  
  Cancer Lett
  
  Volume: 308 Pages: 172-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790545
[Journal Article] The Influence of Excessive IL-6 Production In Vivo on the Development and Function of Foxp3+ Regulatory T Cells2011
- Author(s)
  Fujimoto M, Nakano M, Terabe F, Kawahata H, Ohkawara T, Han Y, Ripley B, Serada S, Nishikawa T, Kimura A, Nomura S, Kishimoto T, Naka T
- Journal Title
  
  J Immunol
  
  Volume: 186 Pages: 32-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790545
[Journal Article] SOCS1 regulates type I/type II NKT cell balance by regulating IFNgamma signaling2011
- Author(s)
  Hashimoto M, Hiwatashi K, Ichiyama K, Morita R, Sekiya T, Kimura A, Sugiyama Y, Sibata T, Kuroda K, Takahashi R, Yoshimura A
- Journal Title
  
  Int Immunol
  
  Volume: 23 Pages: 165-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790545
[Journal Article] Th17 cells in inflammation.2011
- Author(s)
  Kimura A
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 11 Pages: 319-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790468
[Journal Article] Th17 cells in inflammation.2011
- Author(s)
  Kimura A, Kishimoto T.
- Journal Title
  
  Int Immunopharmacol 11
  
  Pages: 319-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790468
[Journal Article] Transcription Factor Smad-Independent T Helper 17 Cell Induction by Transforming-Growth Factor-β Is Mediated by Suppression of Eomesodermin.2011
- Author(s)
  Ichiyama K, Sekiya T, Inoue N, Tamiya T, Kashiwagi I, Kimura A, Morita R, Muto G, Shichita T, Takahashi R, Yoshimura A
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 741-754
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790545
[Journal Article] Transcription Factor Smad-Independent T Helper 17 Cell Induction by Transforming-Growth Factor-ss Is Mediated by Suppression of Eomesodermin2011
- Author(s)
  Kenji Ichiyama, 他
- Journal Title
  
  Immunity
  
  Volume: 34 Issue: 5 Pages: 741-754
- DOI
  10.1016/j.immuni.2011.02.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J05327, KAKENHI-PROJECT-11J02842, KAKENHI-PROJECT-11J04861, KAKENHI-PROJECT-22249009, KAKENHI-PROJECT-22590438, KAKENHI-PROJECT-23659242, KAKENHI-PROJECT-23790545
[Journal Article] Aryl hydrocarbon receptor deficiency in T cells suppresses the development of collagen-induced arthritis2011
- Author(s)
  Nakahama T, Kimura A, Nguyen NT, Chinen I, Hanieh H, Nohara K, Fujii-Kuriyama Y, Kishimoto T.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 108 Issue: 34 Pages: 14222-14227
- DOI
  10.1073/pnas.1111786108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790545
[Journal Article] The Influence of Excessive IL-6 Production In Vivo on the Development and Function of Foxp3+ Regulatory T Cells.2011
- Author(s)
  Fujimoto M, Nakano M, Terabe F, Kawahata H, Ohkawara T, Han Y, Ripley B, Serada S, Nishikawa T, Kimura A, Nomura S, Kishimoto T, Naka T.
- Journal Title
  
  J Immunol 186
  
  Pages: 32-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790468
[Journal Article] Histone 3 lysine 9 (H3K9) methyltransferase recruitment to the interleukin-2 (IL-2) promoter is a mechanism of suppression of IL-2 transcription by the transforming growth factor-β-Smad pathway2011
- Author(s)
  Wakabayashi Y, Tamiya T, Takada I, Fukaya T, Sugiyama Y, Inoue N, Kimura A, Morita R, Kashiwagi I, Takimoto T, Nomura M, Yoshimura A
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 35456-35465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790545
[Journal Article] Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism.2010
- Author(s)
  Nguyen NT, Kimura A, Nakahama T, Chinen I, Masuda K, Nohara K, Fujii-Kuriyama Y, Kishimoto T.
- Journal Title
  
  Proc Natl Acad Sci USA 107
  
  Pages: 19961-19966
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790468
[Journal Article] IL-6 : Regulator of Treg/Th17 balance.2010
- Author(s)
  Kimura A, Kishimoto T.
- Journal Title
  
  Eur J Immunol 40
  
  Pages: 1830-1835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790468
[Journal Article] IL-6 : Regulator of Treg/Th17 balance.2010
- Author(s)
  Kimura A
- Journal Title
  
  Eur J Immunol
  
  Volume: 40 Pages: 1830-1835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790468
[Journal Article] Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses.2009
- Author(s)
  Kimura A
- Journal Title
  
  J Exp Med 206
  
  Pages: 2027-2035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790468
[Journal Article] Aryl hydrocarbon receptor in combination with Statl regulates LPS-induced inflammatory responses.2009
- Author(s)
  Kimura A, Naka T, Nakahama T, Chinen I, Masuda K, Nohara K, Fujii-Kuriyama Y, Kishimoto T.
- Journal Title
  
  J Exp Med 206
  
  Pages: 2027-2035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790468
[Patent] ＩＬ－１０産生誘発ＡｈＲリガンドのスクリーニング方法2013
- Inventor(s)
  木村彰宏、吉村昭彦
- Industrial Property Rights Holder
  学校法人慶應義塾
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-233833
- Filing Date
  2013-11-12
- Data Source
  KAKENHI-PROJECT-25670233
[Presentation] Extracellular aaRSs drive pathogenesis of rheumatoid arthritis via cytokine and PAD4 release2024
- Author(s)
  Akihiro Kimura
- Organizer
  The 52nd Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-21K07088
[Presentation] The AhR-sMaf complex promotes the differentiation of Breg cells.2019
- Author(s)
  Akihiro Kimura and Harumi Suzuki.
- Organizer
  The 48th Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-17K08896
[Presentation] The AhR-Arnt-MafK complex regulates the differentiation of regulatory B cells2018
- Author(s)
  Akihiro Kimura and Harumi Suzuki
- Organizer
  The 47th Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-17K08896
[Presentation] The novel ubiquitin ligase complex, NQO1-PDLIM2 inhibits TLR-dependent production of selective cytokines by degrading IkB-z2017
- Author(s)
  Akihiro Kimura, Masayuki Kitajima and Harumi Suzuki
- Organizer
  The 5th Annual Meeting of the International Cytokine and Interferon
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08896
[Presentation] The novel ubiquitin ligase complex, NQO1-PDLIM2 inhibits TLR-dependent production of selective cytokines by degrading IkB-z2017
- Author(s)
  Akihiro Kimura, Masayuki Kitajima and Harumi Suzuki
- Organizer
  The 46th Annual Meeting of The Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-17K08896
[Presentation] Aryl hydrocarbon receptor controls autoimmunity through regulating the development of regulatory B cells.2013
- Author(s)
  木村彰宏
- Organizer
  第４２回日本免疫学会総会
- Place of Presentation
  幕張メッセ、千葉
- Data Source
  KAKENHI-PROJECT-25670233
[Presentation] Aryl hydrocarbon receptor is important for macrophage survival and protection against Listeria monocytogenes infection2012
- Author(s)
  木村彰宏
- Organizer
  第４１回日本免疫学会総会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-23790545
[Presentation] Aryl hydrocarbon receptor is important for macrophage survival and protection against Listeria monocytogenesinfection2012
- Author(s)
  木村彰宏、吉村昭彦
- Organizer
  第41回日本免疫学会総会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2012-12-06
- Data Source
  KAKENHI-PROJECT-23790545
[Presentation] Aryl hydrocarbon receptor regulates innate immune responses to Listeria monocytogenes2011
- Author(s)
  Akihiro Kimura, Akihiko Yoshimura
- Organizer
  9th Joint Meeting of the ICS/ISICR Firenze
- Place of Presentation
  Italy
- Year and Date
  2011-10-10
- Data Source
  KAKENHI-PROJECT-23790545
[Presentation] Aryl hydrocarbon receptor regulates innate immune responses to Listeria monocytogenes2011
- Author(s)
  Akihiro Kimura, Akihiko Yoshimura
- Organizer
  9th Joint Meeting of the ICS/ISICR
- Place of Presentation
  Firenze, Italy
- Data Source
  KAKENHI-PROJECT-23790545
[Presentation] Aryl hydrocarbon receptor regulates innateimmune responses to Listeria monocytogenes.2011
- Author(s)
  木村彰宏、吉村昭彦
- Organizer
  第40回日本免疫学会総会
- Place of Presentation
  幕張メッセ
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-23790545
[Presentation] ダイオキシン-ダイオキシン受容体によるT細胞分化制御機構の解明2011
- Author(s)
  木村彰宏、吉村昭彦
- Organizer
  第6回日本ケミカルバイオロジー学会
- Place of Presentation
  東京工業大学大岡山キャンパス
- Year and Date
  2011-05-24
- Data Source
  KAKENHI-PROJECT-23790545
[Presentation] ダイオキシン受容体はリステリア感染による免疫応答を制御する2010
- Author(s)
  木村彰宏、吉村昭彦
- Organizer
  第9回感染症沖縄フォーラム
- Place of Presentation
  沖縄国民年金健康センター
- Year and Date
  2010-02-10
- Data Source
  KAKENHI-PROJECT-21790468
[Presentation] Ahr regulates inflammatory responses through T cell, macrophage and B cell function.2010
- Author(s)
  Akihiro Kimura, Tadamitsu Kishimoto.
- Organizer
  14^<th> International Congress of Immunology Kobe
- Place of Presentation
  Japan
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-21790468
[Presentation] Ahr regulates inflammatory responses through T cell, macrophage and B cell function.2010
- Author(s)
  Kimura A
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-22
- Data Source
  KAKENHI-PROJECT-21790468
[Presentation] Aryl hydrocarbon receptor regulates LPS-induced inflammatory responses together with Stat12009
- Author(s)
  木村彰宏
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21790468
[Presentation] Aryl hydrocarbon receptor regulates LPS-induced inflammatory responses together with Statl.2009
- Author(s)
  Akihiro Kimura, Tetsuji Naka, Taisuke Nakahama, Ichino Chinen, Kazuya Masuda, Tadamitsu Kishimoto.
- Organizer
  Cellular and cytokine interactions in health and diseases Lisbon
- Place of Presentation
  Portugal
- Year and Date
  2009-10-20
- Data Source
  KAKENHI-PROJECT-21790468
[Presentation] Aryl hydrocarbon receptor regulates LPS-induced inflammatory responses together with Stat1.2009
- Author(s)
  KIMURA Akihiro, NAKA Tetsuji, NAKAHAMA Taisuke, CHINEN Ichino, MASUDA Kazuya, KISHIMOTO Tadamitsu.
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21790468

1. YOSHIMURA Akihiko (90182815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. SEKIYA Takashi (80519207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. SHICHITA Takashi (00598443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. Suzuki Harumi (70235985)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 森田林平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 北島雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Kimura Akihiro 木村 彰宏

KIMURA Akihiro 木村 彰宏

Research Projects

Research Products

Co-Researchers

細胞外アミノアシルtRNA合成酵素による炎症老化に伴う自己免疫疾患発症機構の解明Principal Investigator

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Development of MS therapy targeting Nqo1Principal Investigator

Principal Investigator

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Effect of novel alarmin on pathogenesis of Rheumatoid Arthrits

Principal Investigator

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Review Section

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Regulation of innate immune responses by NQO1-PDLIM2 axisPrincipal Investigator

Principal Investigator

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Harmine regulates immune responsesPrincipal Investigator

Principal Investigator

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Identification of Cellular Signaling Mechanism that regulates inflammation and tissue repairing

Principal Investigator

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AhR regulates innate immune responses and Th17 cell differentiationPrincipal Investigator

Principal Investigator

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Aryl hydrocarbon receptor regulates innate and acquired immune resposesPrincipal Investigator

Principal Investigator

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[Book] Th17細胞の分化とIL-6の役割. 臨床免疫・アレルギー科、592013

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[Book] Aryl hydrocarbon receptor/IDO産生樹状細胞によるレギュラトリーT細胞の誘導. 臨床免疫・アレルギー科、572012

Author(s)

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[Book] Aryl hydrocarbon receptorによる免疫応答制御機構(臨床免疫・アレルギー科55)2011

Author(s)

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[Book] Aryl hydrocarbon receptorによるLPS応答の制御(臨床免疫・アレルギー科53)2010

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Data Source

[Book] Th17細胞とダイオキシンレセプター(感染・炎症・免疫39)2009

Author(s)

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Data Source

[Book] 感染・炎症・免疫2009

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[Book] Th17細胞の分化とaryl hydrocarbon receptor(臨床免疫・アレルギー科52)2009

Author(s)

Publisher

Kimura Akihiro 木村彰宏

KIMURA Akihiro 木村彰宏