Segawa Katsumori 瀬川勝盛

… Alternative Names

KATSUMORI Segawa 瀬川勝盛

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Researcher Number	20542971
Other IDs
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京医科歯科大学, 難治疾患研究所, 教授 2020: 大阪大学, 免疫学フロンティア研究センター, 特任准教授(常勤) 2019: 大阪大学, 免疫学フロンティア研究センター, 特任准教授 (常勤) 2016 – 2019: 大阪大学, 免疫学フロンティア研究センター, 寄附研究部門准教授 2015: 大阪大学, 免疫学フロンティア研究センター, 寄附研究部門助教 … More 2012 – 2014: 京都大学, 医学(系)研究科(研究院), 助教 2011: 京都大学, 医学(系)研究科(研究院), 研究員 2010: 京都大学, 医学研究科, 特定研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / Biological Sciences / General medical chemistry / Basic Section 48040:Medical biochemistry-related / Transformative Research Areas, Section (III) / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Pathological medical chemistry Except Principal Investigator Transformative Research Areas, Section (III) / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Biological Sciences
Keywords	Principal Investigator 細胞膜 / リン脂質 / ホスファチジルセリン / フリッパーゼ / 非対称性 / マクロファージ / リン脂質移層分子 / 貪食 / 膜タンパク質 / P4型ATPase … More / 細胞死 / スクランブラーゼ / がん細胞 / 自然免疫 / 内因性免疫 / リン脂質移層タンパク質 / 免疫応答 / 脂質移層分子 / 非対称分布 / 小胞体 / ホスファチジルコリン / 基質特異性 / ATPase / 細胞相互作用 / フロッパーゼ / B細胞 / P4-ATPase / ヒト一倍体細胞 / 順遺伝学 / 脂肪組織 … More Except Principal Investigator リン脂質 / 恒常性維持 / 自己認識 / 自己分子 / 免疫センサー / 基質特異性 / 三次構造 / スクランブラーゼ / フリッパーゼ / 貪食 / フォスファチジルセリン / 貪食 / マクロファージ / 自然免疫 / アポトーシス Less

がん組織で機能するリン脂質スクランブラーゼの同定とその生理機能の解明Principal Investigator
- Principal Investigator
  
  瀬川勝盛
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Tokyo Medical and Dental University
自己膜リン脂質の感知機構と内因性免疫Principal Investigator
- Principal Investigator
  
  瀬川勝盛
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Tokyo Medical and Dental University
Self-referential immune perception
- Principal Investigator
  
  山崎晶
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Osaka University
Elucidation of the molecular mechanism of scramblase, and the substrate specificity of flippase
- Principal Investigator
  
  NAGATA Shigekazu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Osaka University
リン脂質の非対称分布の分子機構と生理機能の解明Principal Investigator
- Principal Investigator
  
  瀬川勝盛
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Tokyo Medical and Dental University
Establishment of a method to control distribution of phospholipids in biological membranesPrincipal Investigator
- Principal Investigator
  
  Segawa Katsumori
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Osaka University
Molecular basis for membrane dynamics of phospholipids and its physiology & pathologyPrincipal Investigator
- Principal Investigator
  
  Segawa Katsumori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Osaka University
リン脂質の膜動態と細胞死Principal Investigator
- Principal Investigator
  
  瀬川勝盛
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
P4型ATPaseの基質の同定Principal Investigator
- Principal Investigator
  
  瀬川勝盛
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Mecanisms for the plasma membrane phospholipid asymmetry and its physiological and pathological rolesPrincipal Investigator
- Principal Investigator
  
  Segawa Katsumori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
Identification of phagocytic factors using haploid genetic screens in human cellsPrincipal Investigator
- Principal Investigator
  
  KATSUMORI Segawa
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
脂肪組織常在性マクロファージの生理・病態的意義の解明Principal Investigator
- Principal Investigator
  
  瀬川勝盛
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
Molecular mechanism of the engulfment and degradation of dead cells by macrophages
- Principal Investigator
  
  NAGATA Shigekazu
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
  Kyoto University

[Book] ホスファチジルセリンと死細胞の認識2021
- Author(s)
  瀬川勝盛
- Total Pages
  4
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-21H02682
[Book] 実験医学増刊　細胞死2016
- Author(s)
  瀬川勝盛, 長田重一
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-16H01360
[Book] 実験医学増刊　細胞死2016
- Author(s)
  瀬川勝盛, 長田重一
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15K08266
[Book] Clearance of apoptotic cells and pyrenocytes. In : Curr. Top. Dev. Biol. 114 (Hermann Steller, eds.)2015
- Author(s)
  Toda, S., Nishi, C., Yanagihashi, Y., Segawa, K. and Nagata, S.
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-22000013
[Book] 細胞工学2014
- Author(s)
  瀬川勝盛、長田重一
- Total Pages
  2
- Publisher
  学研メディカル秀潤社
- Data Source
  KAKENHI-PROJECT-24659134
[Book] 「カスパーゼによるフリッパーゼの切断とホスファチジルセリンの露出」「細胞工学」Vol.33, No.122014
- Author(s)
  瀬川勝盛、長田重一
- Publisher
  学研メディカル秀潤社
- Data Source
  KAKENHI-PROJECT-22000013
[Journal Article] リン脂質フリッパーゼとヒト遺伝性疾患2022
- Author(s)
  瀬川勝盛
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 78(2) Pages: 238-244
- Data Source
  KAKENHI-PROJECT-21H04770
[Journal Article] Two types of type IV P-type ATPases independently re-establish the asymmetrical distribution of phosphatidylserine in plasma membranes2022
- Author(s)
  Miyata Yugo、Yamada Kyoko、Nagata Shigekazu、Segawa Katsumori
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 11 Pages: 102527-102527
- DOI
  10.1016/j.jbc.2022.102527
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22H05186, KAKENHI-PROJECT-21H04770, KAKENHI-PROJECT-21H02682
[Journal Article] Protocol to analyze lipid asymmetry in the plasma membrane2022
- Author(s)
  Miyata Yugo、Segawa Katsumori
- Journal Title
  
  STAR Protocols
  
  Volume: 3 Issue: 4 Pages: 101870-101870
- DOI
  10.1016/j.xpro.2022.101870
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22H05186, KAKENHI-PROJECT-21H04770, KAKENHI-PROJECT-21H02682
[Journal Article] カスパーゼによるアポトーシスの実行2022
- Author(s)
  瀬川勝盛, 宮田佑吾
- Journal Title
  
  医学のあゆみ
  
  Volume: 283(5) Pages: 329-334
- Data Source
  KAKENHI-PROJECT-21H04770
[Journal Article] Requirement of Xk and Vps13a for the P2X7-mediated phospholipid scrambling and cell lysis in mouse T cells2022
- Author(s)
  Ryoden Yuta、Segawa Katsumori、Nagata Shigekazu
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 7
- DOI
  10.1073/pnas.2119286119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22H05186, KAKENHI-PROJECT-21H04770, KAKENHI-PROJECT-21H02682
[Journal Article] Inefficient development of syncytiotrophoblasts in the Atp11a-deficient mouse placenta.2022
- Author(s)
  Ochiai Yuki、Suzuki Chigure、Segawa Katsumori、Uchiyama Yasuo、Nagata Shigekazu
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 18
- DOI
  10.1073/pnas.2200582119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22H05186, KAKENHI-PROJECT-21H04770, KAKENHI-PROJECT-21H02682
[Journal Article] Sensing and clearance of apoptotic cells2021
- Author(s)
  Nagata Shigekazu、Segawa Katsumori
- Journal Title
  
  Current Opinion in Immunology
  
  Volume: 68 Pages: 1-8
- DOI
  10.1016/j.coi.2020.07.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-18H02615, KAKENHI-PROJECT-19K22394
[Journal Article] A sublethal ATP11A mutation associated with neurological deterioration causes aberrant phosphatidylcholine flipping in plasma membranes2021
- Author(s)
  Segawa Katsumori、21人、Nagata Shigekazu
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 131 Issue: 18 Pages: 1-17
- DOI
  10.1172/jci148005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04770, KAKENHI-PROJECT-21H02682, KAKENHI-PROJECT-17K18013, KAKENHI-PROJECT-20H03217
[Journal Article] Crystal structure of a human plasma membrane phospholipid flippase2020
- Author(s)
  Nakanishi Hanayo、Irie Katsumasa、Segawa Katsumori、Hasegawa Kazuya、Fujiyoshi Yoshinori、Nagata Shigekazu、Abe Kazuhiro
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 30 Pages: 10180-10194
- DOI
  10.1074/jbc.ra120.014144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-20H00451, KAKENHI-PROJECT-17H03653, KAKENHI-PROJECT-18H02615, KAKENHI-PROJECT-19K22394
[Journal Article] Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM2020
- Author(s)
  Nakanishi Hanayo、Nishizawa Tomohiro、Segawa Katsumori、Nureki Osamu、Fujiyoshi Yoshinori、Nagata Shigekazu、Abe Kazuhiro
- Journal Title
  
  Cell Reports
  
  Volume: 32 Issue: 13 Pages: 108208-108208
- DOI
  10.1016/j.celrep.2020.108208
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-20H00451, KAKENHI-PROJECT-17H03653, KAKENHI-PROJECT-18H02615, KAKENHI-PROJECT-19K22394, KAKENHI-PROJECT-20H03216
[Journal Article] Flippase and scramblase for phosphatidylserine exposure2020
- Author(s)
  Nagata Shigekazu、Sakuragi Takaharu、Segawa Katsumori
- Journal Title
  
  Current Opinion in Immunology
  
  Volume: 62 Pages: 31-38
- DOI
  10.1016/j.coi.2019.11.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-18H02615, KAKENHI-PROJECT-19K22394
[Journal Article] MERTK tyrosine kinase receptor together with TIM4 phosphatidylserine receptor mediates distinct signal transduction pathways for efferocytosis and cell proliferation2019
- Author(s)
  Nishi Chihiro、Yanagihashi Yuichi、Segawa Katsumori、Nagata Shigekazu
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: in press Issue: 18 Pages: 7221-7230
- DOI
  10.1074/jbc.ra118.006628
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05506, KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-18H02615
[Journal Article] リン脂質フリッパーゼとB細胞分化2019
- Author(s)
  瀬川勝盛、長田重一
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 72 Pages: 80-86
- NAID
  40021959396
- Data Source
  KAKENHI-PROJECT-19K22394
[Journal Article] Functional Expression of the P2X7 ATP Receptor Requires Eros2019
- Author(s)
  Ryoden Yuta、Fujii Toshihiro、Segawa Katsumori、Nagata Shigekazu
- Journal Title
  
  The Journal of Immunology
  
  Volume: 204 Issue: 3 Pages: 559-568
- DOI
  10.4049/jimmunol.1900448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-18H02615, KAKENHI-PROJECT-19K22394, KAKENHI-PROJECT-17K15079
[Journal Article] Mechanisms for phosphatidylserine translocation and recognition of dead cells2019
- Author(s)
  瀬川勝盛
- Journal Title
  
  生化学
  
  Volume: 91 Issue: 6 Pages: 743-752
- DOI
  10.14952/SEIKAGAKU.2019.910743
- NAID
  40022117166
- ISSN
  0037-1017
- Year and Date
  2019-12-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22394, KAKENHI-PROJECT-18H02615
[Journal Article] リン脂質フリッパーゼとB細胞分化2019
- Author(s)
  瀬川勝盛、長田重一
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 72 Pages: 80-86
- NAID
  40021959396
- Data Source
  KAKENHI-PROJECT-18H02615
[Journal Article] The CDC50A extracellular domain is required for forming a functional complex with and chaperoning phospholipid flippases to the plasma membrane2018
- Author(s)
  Segawa Katsumori、 Sachiko Kurata、Shigekazu Nagata
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 293 Issue: 6 Pages: 2172-2182
- DOI
  10.1074/jbc.ra117.000289
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01360, KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-15K08266, KAKENHI-PUBLICLY-17H05506
[Journal Article] Phospholipid flippases enable precursor B cells to flee engulfment by macrophages2018
- Author(s)
  Segawa Katsumori、Yanagihashi Yuichi、Yamada Kyoko、Suzuki Chigure、Uchiyama Yasuo、Nagata Shigekazu
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 115 Issue: 48 Pages: 12212-12217
- DOI
  10.1073/pnas.1814323115
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05506, KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-18H02615
[Journal Article] Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosis2017
- Author(s)
  Yanagihashi Yuichi、Segawa Katsumori、Maeda Ryota、Nabeshima Yo-ichi、Nagata Shigekazu
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 114 Issue: 33 Pages: 8800-8805
- DOI
  10.1073/pnas.1705365114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01360, KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-15K08266, KAKENHI-PUBLICLY-17H05506, KAKENHI-PLANNED-26115004
[Journal Article] Characterization of the scrambling domain of the TMEM16 family2017
- Author(s)
  Gyobu Sayuri、Ishihara Kenji、Suzuki Jun、Segawa Katsumori、Nagata Shigekazu
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 114 Issue: 24 Pages: 6274-6279
- DOI
  10.1073/pnas.1703391114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01360, KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-15H05651, KAKENHI-PROJECT-15K08266, KAKENHI-PLANNED-16H06458, KAKENHI-PUBLICLY-17H05506
[Journal Article] Exposure of phosphatidylserine on the cell surface.2016
- Author(s)
  Nagata S, Suzuki J, Segawa K, Fujii T.
- Journal Title
  
  Cell Death Differentiation
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08266
[Journal Article] Human Type IV P-type ATPases that Work as Plasma Membrane Phospholipid Flippases, and Their Regulation by Caspase and Calcium.2016
- Author(s)
  Segawa K, Kurata S, Nagata S.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 289 Issue: 2 Pages: 33543-33556
- DOI
  10.1074/jbc.m115.690727
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08266, KAKENHI-PROJECT-22000013, KAKENHI-PROJECT-15H05785
[Journal Article] Exposure of Phosphatidylserine on the Cell Surface.2016
- Author(s)
  Nagata, S., Suzuki, J., Segawa, K. and Fujii, T.
- Journal Title
  
  Cell Death Differ
  
  Volume: 23 Issue: 6 Pages: 952-961
- DOI
  10.1038/cdd.2016.7
- Description
  印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000013, KAKENHI-PROJECT-15H05651, KAKENHI-PROJECT-15H05785
[Journal Article] An Apoptotic 'Eat Me' Signal: Phosphatidylserine Exposure.2015
- Author(s)
  Segawa K, Nagata S.
- Journal Title
  
  Trends in cell biology
  
  Volume: 25 Issue: 11 Pages: 639-650
- DOI
  10.1016/j.tcb.2015.08.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08266, KAKENHI-PROJECT-22000013, KAKENHI-PROJECT-15H05785
[Journal Article] Clearance of Apoptotic Cells and Pyrenocytes.2015
- Author(s)
  Toda S, Nishi C, Yanagihashi Y, Segawa K, Nagata S.
- Journal Title
  
  Current Topics in Developmental Biology
  
  Volume: 114 Pages: 267-295
- DOI
  10.1016/bs.ctdb.2015.07.017
- ISBN
  9780124104259
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08266, KAKENHI-PROJECT-15K19009
[Journal Article] Tim4-and MerTK-mediated engulfment of apoptotic cells by mouse resident peritoneal macrophages.2014
- Author(s)
  西ちひろ、戸田聡、瀬川勝盛、長田重一
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 34 Issue: 8 Pages: 1512-1520
- DOI
  10.1128/mcb.01394-13
- NAID
  120005458299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05465, KAKENHI-PROJECT-14J03751, KAKENHI-PROJECT-22000013, KAKENHI-PROJECT-24659134
[Journal Article] MerTK-mediated engulfment of pyrenocytes by central macrophages in erythroblastic island.2014
- Author(s)
  S. Toda, K. Segawa, and S. Nagata
- Journal Title
  
  Blood
  
  Volume: in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659134
[Journal Article] MerTK-mediated engulfment of pyrenocytes by central macrophages in erythroblastic islands2014
- Author(s)
  戸田聡、瀬川勝盛、長田重一
- Journal Title
  
  Blood
  
  Volume: (印刷中) Issue: 25 Pages: 3963-3971
- DOI
  10.1182/blood-2014-01-547976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05465, KAKENHI-PROJECT-22000013
[Journal Article] Phospholipid Flippase Activities and Substrate Specificities of Human Type IV P-type ATPases Localized to the Plasma Membrane2014
- Author(s)
  Takatsu, H., Tanaka, G., Segawa, K., Suzuki, J., Nagata, S., Nakayama, K. and Shin, H.W.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 289 Issue: 48 Pages: 33543-33556
- DOI
  10.1074/jbc.m114.593012
- NAID
  120005690224
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22000013, KAKENHI-PROJECT-24659134, KAKENHI-PROJECT-24790278, KAKENHI-PUBLICLY-25113514, KAKENHI-PROJECT-25670165, KAKENHI-PROJECT-26460065
[Journal Article] Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure2014
- Author(s)
  Segawa, K., Kurata, S., Yanagihashi, Y., Brummelkamp, TR., Matsuda, F. and Nagata, S.
- Journal Title
  
  Science
  
  Volume: 344 Issue: 6188 Pages: 1164-1168
- DOI
  10.1126/science.1252809
- NAID
  120005458298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000013, KAKENHI-PROJECT-24659134
[Journal Article] Flippases and scramblases in the plasma membrane2014
- Author(s)
  Segawa, K., Suzuki, J. and Nagata, S.
- Journal Title
  
  Cell Cycle
  
  Volume: 13 Issue: 19 Pages: 2990-2991
- DOI
  10.4161/15384101.2014.962865
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000013, KAKENHI-PROJECT-24659134, KAKENHI-PROJECT-24790278
[Journal Article] Synergistic effect of Tim4 and MFG-E8 null mutations on the development of autoimmunity.2012
- Author(s)
  Miyanishi, M. Segawa, K. and Nagata, S.
- Journal Title
  
  Int Immunol.
  
  Volume: 24 Issue: 9 Pages: 551-559
- DOI
  10.1093/intimm/dxs064
- NAID
  120005300447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000013, KAKENHI-PROJECT-24659134
[Journal Article] Constitutive exposure of phosphatidylserine on viable cells2011
- Author(s)
  Segawa. K, Suzuki. J, Nagata. S
- Journal Title
  
  Proceedings of the National Academy of sciences of the USA
  
  Volume: 108 Issue: 48 Pages: 19246-19251
- DOI
  10.1073/pnas.1114799108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05297, KAKENHI-PROJECT-22000013
[Journal Article] MerTK-mediated engulfment of pyrenocytes by central macrophages in erythroblastic islands.
- Author(s)
  Toda, S., Segawa, K. and Nagata, S.
- Journal Title
  
  Blood
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000013
[Patent] EXPRESSION REGULATOR OF P2X7 RECEPTOR2021
- Inventor(s)
  Nagata S, Ryoden Y, Segawa K
- Industrial Property Rights Holder
  Nagata S, Ryoden Y, Segawa K
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-21H02682
[Patent] Method of screening agents for the treatment　or prevention of cancer or apoptosis-related diseases2014
- Inventor(s)
  Segawa K and Nagata S
- Industrial Property Rights Holder
  Segawa K and Nagata S
- Industrial Property Rights Type
  特許
- Filing Date
  2014-04-08
- Overseas
- Data Source
  KAKENHI-PROJECT-24659134
[Patent] flippaseの同定とアポトーシス時におけるその不活化について2014
- Inventor(s)
  長田重一, 瀬川勝盛
- Industrial Property Rights Holder
  京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-04-08
- Data Source
  KAKENHI-PROJECT-22000013
[Presentation] 細胞膜リン脂質の非対称分布の分子機構と生理作用2023
- Author(s)
  瀬川　勝盛
- Organizer
  第9回JFAS研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04770
[Presentation] 細胞膜リン脂質の非耐用性と生理機能2023
- Author(s)
  瀬川　勝盛
- Organizer
  第11回日本生物工学会コロキウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H04770
[Presentation] 細胞膜リン脂質の非対称性と生理作用2022
- Author(s)
  瀬川　勝盛
- Organizer
  第3回細胞死コロキウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H04770
[Presentation] 細胞膜リン脂質の非対称性と脆弱性2022
- Author(s)
  瀬川　勝盛
- Organizer
  第32回日本サイトメトリー学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04770
[Presentation] Phosphatidylserine-mediated sensing and clearance of dying cells2022
- Author(s)
  瀬川　勝盛
- Organizer
  The 95th Annual meeting of the JBS
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04770
[Presentation] 細胞膜の非対称性と脆弱性2021
- Author(s)
  瀬川勝盛
- Organizer
  千里ライフサイエンスセミナー P5 細胞死研究の新展開
- Invited
- Data Source
  KAKENHI-PROJECT-18H02615
[Presentation] Asymmetry & vulnerability of the plasma membrane2021
- Author(s)
  瀬川　勝盛
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04770
[Presentation] Physiology & Pathology of plasma membrane flippases2021
- Author(s)
  瀬川　勝盛
- Organizer
  The 16th International Symposium of the Institute Network for Biomedical Sciences KEY FORUM 2021 International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04770
[Presentation] Physiology & Pathology of plasma membrane flippases2021
- Author(s)
  Katsumori Segawa
- Organizer
  トランスオミクス医学研究拠点ネットワーク事業 KEY FORUM 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02682
[Presentation] Asymmetry & vulnerability of the plasma membrane2021
- Author(s)
  Katsumori Segawa
- Organizer
  MBSJ2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02682
[Presentation] リン脂質が司る生命現象と疾患2020
- Author(s)
  瀬川勝盛、領田優太、長田重一
- Organizer
  第53回生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22394
[Presentation] Plasam membrane flippase: physiology & pathology2020
- Author(s)
  瀬川勝盛
- Organizer
  東京医科歯科大学難治疾患研究所共同研究拠点研究集会第一回細胞死 Colloquium
- Invited
- Data Source
  KAKENHI-PROJECT-19K22394
[Presentation] 細胞膜の非対称性と脆弱性2020
- Author(s)
  瀬川勝盛
- Organizer
  千里ライフサイエンスセミナー P5 細胞死研究の新展開
- Invited
- Data Source
  KAKENHI-PROJECT-19K22394
[Presentation] リン脂質が司る生命現象と疾患2020
- Author(s)
  瀬川勝盛、領田優太、長田重一
- Organizer
  第53回　生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02615
[Presentation] Plasam membrane flippase: physiology & pathology2020
- Author(s)
  瀬川勝盛
- Organizer
  東京医科歯科大学　難治疾患研究所　共同研究拠点研究集会　第一回細胞死 Colloquium
- Invited
- Data Source
  KAKENHI-PROJECT-18H02615
[Presentation] Phospholipid asymmetry and plasma membrane phospholipid flippases2018
- Author(s)
  Katsumori Segawa
- Organizer
  Membrane Lipid Transporter Symposium 2018
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05506
[Presentation] 細胞膜リン脂質の非対称性とフリッパーゼ2018
- Author(s)
  瀬川　勝盛
- Organizer
  日本Cell Death学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05506
[Presentation] Plasma membrane phospholipid asymmetry and phospholipid flippases2018
- Author(s)
  Katsumori Segawa
- Organizer
  Frontiers in P-type ATPase Research 2018
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05506
[Presentation] 細胞膜リン脂質の非対称性とフリッパーゼ2018
- Author(s)
  瀬川　勝盛
- Organizer
  日本Cell Death学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02615
[Presentation] Plasma membrane phospholipid asymmetry and phospholipid flippases2018
- Author(s)
  Katsumori Segawa
- Organizer
  Frontiers in P-type ATPase Research 2018
- Invited
- Data Source
  KAKENHI-PROJECT-18H02615
[Presentation] Phospholipid asymmetry and plasma membrane phospholipid flippases2018
- Author(s)
  katsumori Segawa
- Organizer
  Membrane Lipid Transporter Symposium 2018
- Invited
- Data Source
  KAKENHI-PROJECT-18H02615
[Presentation] Function and regulation of plasma membrane phospholipid flippases2017
- Author(s)
  Katsumori Segawa and Shigekazu Nagata
- Organizer
  The 15th international conference on Na,K-ATPase and related transport Atlases
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08266
[Presentation] Function and regulation of plasma membrane phospholipid flippases2017
- Author(s)
  Katsumori Segawa and Shigekazu Nagata
- Organizer
  The 15th international conference on Na,K-ATPase and related transport Atlases
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01360
[Presentation] カスパーゼによるリン脂質フリッパーゼの切断とホスファチジルセリンの暴露2015
- Author(s)
  瀬川勝盛、長田重一
- Organizer
  BMB2015(第38回日本分子生物学会年会・第88回日本生化学会大会合同大会)シンポジウム
- Place of Presentation
  神戸ポートピアホテル兵庫
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-22000013
[Presentation] Caspase-mediated cleavage of phospholipid flippase for phosphatidylserine exposure during apoptosis2015
- Author(s)
  Segawa K, Nagata S
- Organizer
  日本生化学会年会　日本分子生物学会年会　合同大会
- Place of Presentation
  兵庫県神戸市、神戸ポートピアランド
- Year and Date
  2015-12-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08266
[Presentation] The molecular mechanism of the engulfment of nuclei extruded from erythroblasts in the erythroblastic islands.2013
- Author(s)
  戸田聡、瀬川勝盛、長田重一
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜神奈川(口頭発表)
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-22000013
[Presentation] Requirement of Tim4 and Mer on the engulfment of apoptotic cells by peritoneal macrophage.2013
- Author(s)
  西ちひろ、瀬川勝盛、長田重一
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜神奈川(口頭発表)
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-22000013
[]

1. NAGATA Shigekazu (70114428)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
2. SUZUKI Jun (30511894)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. FUJII Toshihiro (30580104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. HANAYAMA Rikinari (40403191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 櫻木崇晴 (10867906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山崎晶 (40312946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 三宅健介 (60229812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 和泉自泰 (70622166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 改正恒康 (60224325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 安友康二 (30333511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 木村元子 (00345018)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 浅野謙一 (10513400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 堀昌平 (50392113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SULTAN CHERYL

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 戸田聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Segawa Katsumori 瀬川 勝盛

KATSUMORI Segawa 瀬川 勝盛

Research Projects

Research Products

Co-Researchers

がん組織で機能するリン脂質スクランブラーゼの同定とその生理機能の解明Principal Investigator

Principal Investigator

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自己膜リン脂質の感知機構と内因性免疫Principal Investigator

Principal Investigator

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Self-referential immune perception

Principal Investigator

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Review Section

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Elucidation of the molecular mechanism of scramblase, and the substrate specificity of flippase

Principal Investigator

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Review Section

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リン脂質の非対称分布の分子機構と生理機能の解明Principal Investigator

Principal Investigator

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Review Section

Research Institution

Establishment of a method to control distribution of phospholipids in biological membranesPrincipal Investigator

Principal Investigator

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Molecular basis for membrane dynamics of phospholipids and its physiology & pathologyPrincipal Investigator

Principal Investigator

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Review Section

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リン脂質の膜動態と細胞死Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

P4型ATPaseの基質の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mecanisms for the plasma membrane phospholipid asymmetry and its physiological and pathological rolesPrincipal Investigator

Principal Investigator

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Research Institution

Identification of phagocytic factors using haploid genetic screens in human cellsPrincipal Investigator

Principal Investigator

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脂肪組織常在性マクロファージの生理・病態的意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of the engulfment and degradation of dead cells by macrophages

Principal Investigator

Project Period (FY)

Segawa Katsumori 瀬川勝盛

KATSUMORI Segawa 瀬川勝盛

[Book] 実験医学増刊　細胞死2016

[Book] 実験医学増刊　細胞死2016