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MASAKI HIDEKI  正木 英樹

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Hideki Masaki  正木 英樹

Masaki Hideki  正木 英樹

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Researcher Number 20571988
Other IDs
Affiliation (Current) 2025: 東京科学大学, 総合研究院, 特任准教授
Affiliation (based on the past Project Information) *help 2024: 東京医科歯科大学, 高等研究院, 特任助教
2023: 東京医科歯科大学, 高等研究院, プロジェクト准教授
2021 – 2023: 東京医科歯科大学, 高等研究院, プロジェクト助教
2020 – 2021: 東京大学, 医科学研究所, 特任助教
2015 – 2016: 東京大学, 医科学研究所, 助教
Review Section/Research Field
Principal Investigator
Basic Section 42040:Laboratory animal science-related / Laboratory animal science
Except Principal Investigator
Basic Section 55010:General surgery and pediatric surgery-related / Medium-sized Section 42:Veterinary medical science, animal science, and related fields
Keywords
Principal Investigator
多能性幹細胞 / キメラ / 発生 / カニクイザル / blastoid / 霊長類 / チンパンジー / 臓器再生 / 再生医療 / iPS細胞 … More / 統合胚 / 繁殖 / 臓器移植 / ナイーブ型多能性幹細胞 / 多能性 / 臓器 / ウサギ / 遺伝子改変動物 / ES細胞 … More
Except Principal Investigator
胚盤胞補完法 / 肝移植 / 臓器再生 / 胚盤胞 / ヒト胚 / 不妊 / 胎盤 / ナイーブ / 膵臓 / 再生医学 / 胎児移植 / 臓器創出 / exo utero移植 / 多能性幹細胞 / 異種間キメラ / 臓器作製 Less
  • Research Projects

    (6 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (8 People)
  •  非ヒト霊長類の着床、胎盤形成機構の解明とヒトへの展開

    • Principal Investigator
      依馬 正次
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      Shiga University of Medical Science
  •  in vivo development of non-human primate blastoidsPrincipal Investigator

    • Principal Investigator
      正木 英樹
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of technology for creating transplantable livers using in vivo environments

    • Principal Investigator
      鈴木 悠地
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Iwate Medical University
  •  Generation of human pancreas in xenogeneic animal

    • Principal Investigator
      Yamaguchi Tomoyuki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Tokyo University of Pharmacy and Life Science
      The University of Tokyo
  •  Development of in vitro chimera assay system utilizing cynomolgus monkey embryosPrincipal Investigator

    • Principal Investigator
      Hideki Masaki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Tokyo Medical and Dental University
      The University of Tokyo
  •  Development of new procedure to make chimeric animals without using naive pluripotent stem cellsPrincipal Investigator

    • Principal Investigator
      Masaki Hideki
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      The University of Tokyo

All 2023 2022 2021 2016 2015

All Journal Article Presentation

  • [Journal Article] PDGF Receptors and Signaling Are Required for 3D-Structure Formation and Differentiation of Human iPSC-Derived Hepatic Spheroids.2023

    • Author(s)
      3.Syusaku Tsuzuki Tomoyuki Yamaguchi Takashi Okumura Toshiharu Kasai  and Hideki Taniguchi
    • Journal Title

      Int.J.Mol.Sci.

      Volume: 24(8) Issue: 8 Pages: 7075-7075

    • DOI

      10.3390/ijms24087075

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03740, KAKENHI-PROJECT-23K18143, KAKENHI-PROJECT-22K08807, KAKENHI-PROJECT-23K08053, KAKENHI-PROJECT-21H02991, KAKENHI-PROJECT-23K27667
  • [Journal Article] In vitro and in vivo functions of T cells produced in complemented thymi of chimeric mice generated by blastocyst complementation.2022

    • Author(s)
      Yamazaki K, Kubara K, Ishii S, Li P, Dairiki R, Hihara T, Ishizuka Y, Izumi Y, Kumai M, Kamisako T, Ishizaki H, Sato H, Masaki H, Mizuno N, Mitsuhashi K, Ito M, Hamanaka S, Yamaguchi T, Watanabe M, Sugiyama F, Nakauchi H.
    • Journal Title

      Sci Rep.

      Volume: 12(1) Issue: 1 Pages: 3242-3242

    • DOI

      10.1038/s41598-022-07159-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03740
  • [Journal Article] Interspecific in vitro assay for the chimera-forming ability of human pluripotent stem cells.2015

    • Author(s)
      Masaki H, Kato-Itoh M, Umino A, Sato H, Hamanaka S, Kobayashi T, Yamaguchi T, Nishimura K, Ohtaka M, Nakanishi M, Nakauchi H.
    • Journal Title

      Development.

      Volume: 142(18) Pages: 3222-30

    • DOI

      10.1242/dev.124016

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460358, KAKENHI-PROJECT-15K20948, KAKENHI-PROJECT-25460354, KAKENHI-PROJECT-26870074
  • [Presentation] チンパンジー多能性幹細胞を用いた異種間キメラ形成能の評価2022

    • Author(s)
      正木英樹
    • Organizer
      Annual Meeting of International Society of Stem Cell Research, 2022年6月15日 San Francisco
    • Data Source
      KAKENHI-PROJECT-20H03170
  • [Presentation] ヒト臓器作製を目的としたヒト→動物キメラ作出研究の課題と展望2022

    • Author(s)
      正木英樹
    • Organizer
      第21回再生医療学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03170
  • [Presentation] Xenobarrier in human-mouse interspecies chimeras2022

    • Author(s)
      正木英樹
    • Organizer
      第37回日本発生生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H03170
  • [Presentation] XENOBARRIER IN HUMAN-MOUSE INTERSPEICIES CHIMERA FORMATION2022

    • Author(s)
      Hideki Masaki, Hiromitsu Nakauchi
    • Organizer
      Annual Meeting of International Society of Stem Cell Research, 2022年6月15日 San Francisco
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03170
  • [Presentation] チンパンジー多能性幹細胞を用いた異種間キメラ形成能の評価2022

    • Author(s)
      正木英樹
    • Organizer
      第50回ホミニゼーション研究会
    • Data Source
      KAKENHI-PROJECT-20H03170
  • [Presentation] 臓器ニッチおよび細胞競合ニッチを利用した異種個体内での移植臓器作出2021

    • Author(s)
      中内 啓光,西村 俊哉,正木 英樹,山口 智之
    • Organizer
      第42回日本炎症・再生医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03740
  • [Presentation] Predict the unpredictable: using the in vivo niche to assess lineage potential and functionality of PSC-derived cells2016

    • Author(s)
      Hideki Masaki
    • Organizer
      Annual Meeting of International Society for Stem Cell Research
    • Place of Presentation
      Moscone Center, San Francisco CA, USA
    • Year and Date
      2016-06-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K20948
  • [Presentation] A UNIQUE SYSTEM TO ASSESS THE IN VIVO LINEAGE POTENTIALS OF DEVELOPMENTALLY-ADVANCED CELLS BY BLASTOCYST INJECTION2016

    • Author(s)
      Hideki Masaki
    • Organizer
      Annual Meeting of International Society for Stem Cell Research
    • Place of Presentation
      Moscone Center, San Francisco CA, USA
    • Year and Date
      2016-06-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K20948
  • [Presentation] A unique system to assess the in vivo lineage potentials of developmentally-advanced progenitors2016

    • Author(s)
      正木英樹
    • Organizer
      日本再生医療学会年会
    • Place of Presentation
      大阪国際展示場(大阪府大阪市)
    • Year and Date
      2016-03-17
    • Data Source
      KAKENHI-PROJECT-15K20948
  • [Presentation] 幹細胞研究における生体環境利用の有用性2016

    • Author(s)
      正木英樹
    • Organizer
      日本再生医療学会
    • Place of Presentation
      大阪国際展示場(大阪府大阪市)
    • Year and Date
      2016-03-17
    • Data Source
      KAKENHI-PROJECT-15K20948
  • [Presentation] Novel chimera forming technology by preventing cell death2015

    • Author(s)
      正木英樹
    • Organizer
      日本分子生物学会年会
    • Place of Presentation
      神戸国際展示場(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K20948
  • 1.  水谷 英二 (80443034)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  依馬 正次 (60359578)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  Yamaguchi Tomoyuki (80392158)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 4.  松本 翔馬 (00881517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  辻 俊一郎 (30601546)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  武藤 真長 (50868867)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  鈴木 悠地 (00779332)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  片桐 弘勝 (30714422)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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