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OKUDA TAKAHISA  奥田 貴久

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OKUDA Takahisa  奥田 貴久

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Researcher Number 20620305
Other IDs
Affiliation (Current) 2025: 日本大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2025: 日本大学, 医学部, 教授
2019 – 2023: 日本大学, 医学部, 教授
2017 – 2019: 日本医科大学, 医学部, 准教授
2016: 日本医科大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Basic Section 58040:Forensics medicine-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 59040:Nutrition science and health science-related / Legal medicine
Except Principal Investigator
Basic Section 58010:Medical management and medical sociology-related / Basic Section 58040:Forensics medicine-related / Basic Section 56020:Orthopedics-related / Basic Section 56060:Ophthalmology-related / Legal medicine
Keywords
Principal Investigator
個人識別 / ナノポアテクノロジー / ロングリードシークエンサー / アルコール脂肪肝 / 突然死 / 骨粗鬆症 / 脂肪肝 / アルコール脱水素酵素 / 社会医学 / シミュレーション工学 … More / 循環器 / 心タンポナーデ / 応力 / 生体シミュレーション / コンピューターシミュレーション / 心嚢破裂 … More
Except Principal Investigator
医学教育 / 臨床推論 / マルチメディア / 模擬患者 / PBL / miRNA / 動脈硬化 / 遺伝子 / SNP / 相関性の解析 / CAD病理学的評価 / TaqMan Assayの解析 / MicroRNAマーカー / 血漿試料の収集 / 日本人集団 / 遺伝的多様性 / 法医学解剖 / CAD / SNPs / TaqMan Assay / MicroRNA / 整形外科学 / NKT細胞 / HIF2α / Interleukin 4 / Natural killer T細胞 / エタノール / IL-4 / 変形性膝関節症 / NKT様細胞 / 骨強度 / 骨代謝 / GSNOR / I型コラーゲン / HIF2α / 変形性関節症 / ClassⅢアルコール脱水素酵素 / S-ニトロソグルタチオン還元酵素 / 網膜色素変性モデル / 治療 / 水素 / 網膜色素変性 / 酵素 / 社会医学 / 慢性飲酒 / ADH1 / ADH3 / 肝障害 / アルコール代謝 / アルコール脱水素酵素 Less
  • Research Projects

    (9 results)
  • Research Products

    (38 results)
  • Co-Researchers

    (23 People)
  •  ナノポアシークエンサーによる個人識別-劣化および混合DNA試料の新規分析法の開発Principal Investigator

    • Principal Investigator
      奥田 貴久
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      Nihon University
  •  マルチメディア模擬患者の開発とオンライン参加型PBLによる臨床推論力の可視化

    • Principal Investigator
      阿部 百合子
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58010:Medical management and medical sociology-related
    • Research Institution
      Nihon University
  •  miRNA発現パターンと病理所見に基づく機械学習による冠動脈硬化症のクラスター化

    • Principal Investigator
      鉄 堅
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      Nihon University
  •  ロングリードシークエンスを用いた混合ゲノム試料解析の探索的研究Principal Investigator

    • Principal Investigator
      奥田 貴久
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 58:Society medicine, nursing, and related fields
    • Research Institution
      Nihon University
  •  変形性膝関節症におけるS-ニトロソグルタチオン還元酵素と自然免疫系細胞の役割

    • Principal Investigator
      成尾 宗浩
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Nippon Medical School
  •  Alcohol dehydrogenase in alcohol-related organ disorderPrincipal Investigator

    • Principal Investigator
      OKUDA Takahisa
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Nihon University
  •  Neuroprotection of phtoreceptor by drinking hydrogen water on retinitis pigmentosa model

    • Principal Investigator
      Igarashi Toru
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Nippon Medical School
  •  The mechanism of pericardial rupture associated with cardiopulmonary resuscitation involving chest compressionPrincipal Investigator

    • Principal Investigator
      OKUDA Takahisa
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Nippon Medical School
  •  Enzymatic and metabolic adaptation to chronic alcohol consumption mediated by alcohol dehydrogenase 1 and 3 in mice.

    • Principal Investigator
      Ohno Youkichi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Nippon Medical School

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] A Case Report of Acute Cardiac Tamponade Creation in a Macaque: Echo-Guided Catheter Manipulation to Perforate Coronary Artery2023

    • Author(s)
      Takanari Hiroki、Okuyama Minami W、Kuroki Kohji、Kondo Hidekazu、Kira Shintaro、Miura Masahiro、Takahashi Naohiko、Okuda Takahisa
    • Journal Title

      Yonago Acta Medica

      Volume: 66 Issue: 1 Pages: 192-195

    • DOI

      10.33160/yam.2023.02.022

    • ISSN
      0513-5710, 1346-8049
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19675, KAKENHI-PROJECT-19H04038, KAKENHI-PROJECT-21K19913, KAKENHI-PROJECT-22K09289
  • [Journal Article] Role of miR-143 and miR-146 in Risk Evaluation of Coronary Artery Diseases in Autopsied Samples2023

    • Author(s)
      Tie Jian、Takanari Hiroki、Ota Koya、Okuda Takahisa
    • Journal Title

      Genes

      Volume: 14 Issue: 2 Pages: 471-471

    • DOI

      10.3390/genes14020471

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19675, KAKENHI-PROJECT-19H04038, KAKENHI-PROJECT-21K19913, KAKENHI-PROJECT-21K10533
  • [Journal Article] Sudden death of a child associated with invasive non-typeable Haemophilus influenzae infection with underlying IgG2 subclass deficiency2023

    • Author(s)
      Abe Yuriko、Takano Chika、Tie Jian、Isobe Eiji、Ohirabaru Ayumi、Isahai Isamu、Nishiyama Hiroyuki、Jike Toyoharu、Masuda Shinobu、Okuda Takahisa
    • Journal Title

      Legal Medicine

      Volume: 62 Pages: 102240-102240

    • DOI

      10.1016/j.legalmed.2023.102240

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19675, KAKENHI-PROJECT-19H04038
  • [Journal Article] Class III Alcohol Dehydrogenase Plays a Key Role in the Onset of Alcohol-Related/-Associated Liver Disease as an S-Nitrosoglutathione Reductase in Mice.2023

    • Author(s)
      Haseba T, Maruyama M, Akimoto T, Yamamoto I, Katsuyama M, Okuda T.
    • Journal Title

      Int J Mol Sci.

      Volume: 24 Issue: 15 Pages: 12102-12102

    • DOI

      10.3390/ijms241512102

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H04038
  • [Journal Article] Roles of radiological technologists at Tsukuba Medical Examiner's Office equipped with a computed tomography system dedicated for the examination of corpses2022

    • Author(s)
      Kobayashi Tomoya、Shiotani Seiji、Tashiro Kazuya、Someya Satoka、Yoshida Masahiro、Numano Tomokazu、Hayakawa Hideyuki、Okuda Takahisa
    • Journal Title

      Forensic Imaging

      Volume: 30 Pages: 200508-200508

    • DOI

      10.1016/j.fri.2022.200508

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H04038, KAKENHI-PROJECT-20K18984
  • [Journal Article] 口腔内液(唾液)中DNAに関する研究(第2報).2021

    • Author(s)
      千葉 正悦, 呂 彩子, 向井 敏二, 早田 詩織, 飯酒盃 勇, 鉄 堅, 磯部 英二, 内ヶ崎 西作, 奥田 貴久
    • Journal Title

      DNA多型

      Volume: 29(1) Pages: 95-100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K19675
  • [Journal Article] Fatal Traffic Accidents in Japan2021

    • Author(s)
      Takahisa Okuda
    • Journal Title

      Journal of Nihon University Medical Association

      Volume: 80 Issue: 2 Pages: 97-99

    • DOI

      10.4264/numa.80.2_97

    • NAID

      130008057478

    • ISSN
      0029-0424, 1884-0779
    • Year and Date
      2021-04-01
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H04038
  • [Journal Article] Brain-derived Neurotrophic Factor in the Aqueous Humor of Glaucoma Patients2021

    • Author(s)
      Igarashi Tsutomu、Nakamoto Kenji、Kobayashi Maika、Suzuki Hisaharu、Arima Takeshi、Tobita Yutaro、Takao Kazuhiro、Igarashi Toru、Okuda Takahisa、Okada Takashi、Takahashi Hiroshi
    • Journal Title

      Journal of Nippon Medical School

      Volume: 88 Issue: 2 Pages: 128-132

    • DOI

      10.1272/jnms.JNMS.2021_88-305

    • NAID

      130008037216

    • ISSN
      1345-4676, 1347-3409
    • Year and Date
      2021-04-24
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H04038, KAKENHI-PROJECT-23K20328
  • [Journal Article] Alcohol consumption induces murine osteoporosis by downregulation of natural killer T‐like cell activity2021

    • Author(s)
      Naruo Munehiro、Negishi Yasuyuki、Okuda Takahisa、Katsuyama Midori、Okazaki Ken、Morita Rimpei
    • Journal Title

      Immunity, Inflammation and Disease

      Volume: 9 Issue: 4 Pages: 1370-1382

    • DOI

      10.1002/iid3.485

    • NAID

      120007183291

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H04038, KAKENHI-PROJECT-20K09512, KAKENHI-PROJECT-20K09679
  • [Journal Article] Detection of deletion/insertion polymorphism profiles from single human hair shafts.2021

    • Author(s)
      Tie J, Uchigasaki S, Isobe E, Iwakami E, Okuda T:
    • Journal Title

      Mol Biol Rep

      Volume: 49(2) Issue: 2 Pages: 1017-1025

    • DOI

      10.1007/s11033-021-06921-w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K19675
  • [Journal Article] Biomedical Research on Alcohol and Alcohol Dehydrogenase2021

    • Author(s)
      Okuda Takahisa
    • Journal Title

      Journal of Nihon University Medical Association

      Volume: 80 Issue: 4 Pages: 199-202

    • DOI

      10.4264/numa.80.4_199

    • NAID

      130008101896

    • ISSN
      0029-0424, 1884-0779
    • Year and Date
      2021-08-01
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H04038
  • [Journal Article] Roles of Two Major Alcohol Dehydrogenases, ADH1 (Class I) and ADH3 (Class III), in the Adaptive Enhancement of Alcohol Metabolism Induced by Chronic Alcohol Consumption in Mice.2020

    • Author(s)
      akeshi Haseba , Takahisa Okuda , Motoyo Maruyama , Toshio Akimoto , Gregg Duester , Youkichi Ohno
    • Journal Title

      Alcohol and alcoholism (Oxford, Oxfordshire)

      Volume: 55(1) Issue: 1 Pages: 11-19

    • DOI

      10.1093/alcalc/agz091

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H04038
  • [Journal Article] Serum Brain-Derived Neurotrophic Factor in Glaucoma Patients in Japan: An Observational Study2020

    • Author(s)
      Tsutomu Igarashi , Kenji Nakamoto , Maika Kobayashi , Hisaharu Suzuki , Yutaro Tobita , Toru Igarashi , Takahisa Okuda , Takashi Okada , Hiroshi Takahashi
    • Journal Title

      Journal of Nippon Medical School

      Volume: 87 Issue: 6 Pages: 339-345

    • DOI

      10.1272/jnms.JNMS.2020_87-605

    • NAID

      130007966496

    • ISSN
      1345-4676, 1347-3409
    • Year and Date
      2020-12-15
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H04038, KAKENHI-PROJECT-23K20328
  • [Journal Article] The Effect of Alcohol Dehydrogenase Isozymes on Alcoholic Liver Disease and Alcoholic Osteoporosis2019

    • Author(s)
      Okuda Takahisa
    • Journal Title

      Journal of Nippon Medical School

      Volume: 86 Issue: 1 Pages: 58-59

    • DOI

      10.1272/jnms.JNMS.2019_86-11

    • NAID

      130007620538

    • ISSN
      1345-4676, 1347-3409
    • Year and Date
      2019-01-15
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09223, KAKENHI-PROJECT-19H04038
  • [Journal Article] Metabolic pharmacokinetics of early chronic alcohol consumption mediated by liver alcohol dehydrogenases 1 and 3 in mice2018

    • Author(s)
      Okuda Takahisa、Haseba Takeshi、Katsuyama Midori、Maruyama Motoyo、Akimoto Toshio、Igarashi Tsutomu、Ohno Youkichi
    • Journal Title

      Journal of Gastroenterology and Hepatology

      Volume: 33 Issue: 11 Pages: 1912-1919

    • DOI

      10.1111/jgh.14260

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K17421, KAKENHI-PROJECT-16K09223
  • [Journal Article] Principles of fetal postmortem ultrasound: a personal review2016

    • Author(s)
      Okuda T, Shiotani S, Kobayashi T
    • Journal Title

      J Forensic Radilo Imaging.

      Volume: 5 Pages: 50-1

    • DOI

      10.1016/j.jofri.2016.04.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09223
  • [Journal Article] Principles of fetal postmortem ultrasound: a personal review.2016

    • Author(s)
      Okuda T, Shiotani S, Kobayashi T.
    • Journal Title

      J Forensic Radiol Imaging.

      Volume: 5 Issue: 1 Pages: 50-1

    • DOI

      10.1016/j.jofri.2015.01.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09222
  • [Presentation] 閉経後骨粗鬆症モデルマウスにおける免疫系のダウンレギュレーション―新たな発症メカニズムの考察―2023

    • Author(s)
      樋口百合花、根岸靖幸、成尾宗浩、大内 望、鈴木俊治、奥田貴久、森田林平
    • Organizer
      日本骨免疫学会
    • Data Source
      KAKENHI-PROJECT-19H04038
  • [Presentation] 第三世代シーケンサー「MinION」による全ミトコンドリアDNA配列読み取り精度について2023

    • Author(s)
      太田昂矢、千葉昭悦、鉄堅、山口るつ子、奥田貴久
    • Organizer
      日本DNA多型学会
    • Data Source
      KAKENHI-PROJECT-21K19675
  • [Presentation] Role of miR-143 and miR-146 in Risk Evaluation of Coronary Artery Diseases in Autopsied Samples2023

    • Author(s)
      Jian Tie, Koya Ota, Takahisa Okuda
    • Organizer
      23rd Triennial Meeting of the International Association of Forensic Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K10533
  • [Presentation] ClassⅢアルコール脱水素酵素はマウス皮質骨のコラーゲン配向性を制御する2023

    • Author(s)
      成尾宗浩、根岸靖幸、奥田貴久、森田林平
    • Organizer
      日本骨免疫学会
    • Data Source
      KAKENHI-PROJECT-19H04038
  • [Presentation] 口腔内液(唾液)中DNAに関する研究(第4報)2022

    • Author(s)
      千葉正悦、奥田貴久、他
    • Organizer
      日本DNA多型学会第31回学術集会
    • Data Source
      KAKENHI-PROJECT-21K19675
  • [Presentation] Role of innate immune cells in postmenopausal osteoporosis: An osteoimmunological perspective2021

    • Author(s)
      Yasuyuki Negishi1, 2, Munehiro Naruo, Nozomi Ouchi, Takahisa Okuda, Toshiyuki Takeshita, Rimpei Morita
    • Organizer
      第40回米国生殖免疫学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09512
  • [Presentation] 法医学から発信するアルコール・薬物研究~これまでと今後の展望 エタノール代謝に及ぼすカフェインの影響について2021

    • Author(s)
      磯部 英二, 奥田 貴久
    • Organizer
      薬物依存関連学会合同学術総会
    • Data Source
      KAKENHI-PROJECT-19H04038
  • [Presentation] アルコール摂取がマウスの腎臓に及ぼす形態変化と生化学的変動.2020

    • Author(s)
      勝山 碧, 長谷場健, 丸山基世, 秋元敏雄, 奥田貴久.
    • Organizer
      第104次日本法医学会学術全国集会.
    • Data Source
      KAKENHI-PROJECT-19H04038
  • [Presentation] 多臓器を対象としたアルコール医学研究2020

    • Author(s)
      奥田貴久
    • Organizer
      日本大学医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H04038
  • [Presentation] アルコールがマウス腎に及ぼす影響.2020

    • Author(s)
      勝山 碧, 長谷場健, 奥田貴久.
    • Organizer
      第39回アルコール医学生物学研究会学術集会.
    • Data Source
      KAKENHI-PROJECT-19H04038
  • [Presentation] 経胸壁心エコーガイド下カテーテル法による急性心タンポナーデ動物実験モデルの開発2020

    • Author(s)
      奥田貴久、髙成広起、黒木浩二、奥山みなみ、三浦真弘
    • Organizer
      第104次日本法医学会
    • Data Source
      KAKENHI-PROJECT-16K09222
  • [Presentation] アルコール過量摂取に伴う続発性骨粗鬆症における自然免疫細胞の役割.2020

    • Author(s)
      成尾宗浩, 根岸靖幸, 奥田貴久, 岡崎 賢, 森田林平
    • Organizer
      第93回日本整形外科学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H04038
  • [Presentation] 多臓器を対象としたアルコール基礎研究の問題点2019

    • Author(s)
      奥田貴久, 勝山碧, 長谷場健, 成尾宗浩, 根岸靖幸
    • Organizer
      2019年度アルコール薬物依存関連学会合同学術総会
    • Data Source
      KAKENHI-PROJECT-19H04038
  • [Presentation] アルコール性骨粗鬆症についての免疫学的考察2019

    • Author(s)
      奥田貴久, 成尾宗浩, 根岸靖幸,勝山碧,長谷場健,大野曜吉
    • Organizer
      第103回日本法医学会学術全国集会
    • Data Source
      KAKENHI-PROJECT-19H04038
  • [Presentation] 慢性エタノール摂取マウスにおける腎の形態変化2019

    • Author(s)
      勝山碧,長谷場健,佐佐木喜広,和田健太朗,丸山基世, 秋元敏雄,奥田貴久
    • Organizer
      第62回腎臓学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H04038
  • [Presentation] Enzymatic and metabolic adaptation to ethanol by alcohol dehydrogenase 1 and 3 in mice.2018

    • Author(s)
      T.Okuda et al.
    • Organizer
      24th Congress of International Academy of Legal Medicine (Fukuoka).
    • Data Source
      KAKENHI-PROJECT-16K09223
  • [Presentation] 慢性アルコール摂取の骨に及ぼす影響とClassⅢアルコール脱水素酵素(ADH3)の役割2017

    • Author(s)
      奥田貴久、成尾宗弘、大野曜吉、長谷場健.
    • Organizer
      日本法医学学会
    • Data Source
      KAKENHI-PROJECT-16K09223
  • [Presentation] The role of Class III Alcohol Dehydrogenase (ADH3) in alcohol-related disorder on liver and bone.2017

    • Author(s)
      Okuda T, Maruyama M, Akimoto T, Ohno Y, Haseba T.
    • Organizer
      .2017 ESBRA Congres
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09223
  • [Presentation] High km アルコール脱水素酵素3(ADH3)のアルコール摂取量ならびにアルコール性肝障害発症における役割.2016

    • Author(s)
      長谷場健、奥田貴久、他.
    • Organizer
      日本アルコール・アディクション学会
    • Place of Presentation
      東京
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PROJECT-16K09222
  • [Presentation] 死後超音波のコントラストが不明瞭な理由.2016

    • Author(s)
      奥田貴久、早川秀幸、塩谷清司、大野曜吉
    • Organizer
      日本法医学会
    • Place of Presentation
      東京
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PROJECT-16K09222
  • [Presentation] Roles of high km ADH3 in an increase in alcohol metabolism by chronic alcohol consumption and in development of alcoholic liver disease.2016

    • Author(s)
      Haseba T, Maruyama M, Akimoto T, Okuda T.
    • Organizer
      ISBRA/ESBRA Congress 2016
    • Place of Presentation
      Berlin
    • Year and Date
      2016-09-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09222
  • 1.  高成 広起 (70723253)
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  • 2.  五十嵐 勉 (10421190)
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  • 11.  高橋 浩 (00188046)
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  • 13.  草野 麻衣子 (60733574)
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  • 14.  勝山 碧 (90803700)
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  • 15.  内ヶ崎 西作 (30223548)
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  • 16.  近藤 真啓 (50312294)
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  • 17.  橋本 悟 (60352150)
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  • 18.  阿部 百合子 (70750660)
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  • 19.  大谷 尚子 (50584778)
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  • 20.  糸井 充穂 (40422448)
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  • 21.  横瀬 宏美 (40465274)
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  • 22.  鈴木 沙季 (10896129)
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  • 23.  HASEBA takeshi
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