Minamishima Shizuka 南嶋しづか

… Alternative Names

MINAMISHIMA Shizuka 南嶋しづか

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Researcher Number	20622088
Other IDs	https://orcid.org/0000-0002-4675-5391
Affiliation (Current)	2025: 群馬県衛生環境研究所, 研究企画係, 研究員
Affiliation (based on the past Project Information) *help	2025: 群馬県衛生環境研究所, 研究企画係, 研究員 2020 – 2022: 群馬県衛生環境研究所, 研究企画係, 研究員 2017 – 2019: 慶應義塾大学, 医学部(信濃町), 講師 2012 – 2014: 慶應義塾大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 55060:Emergency medicine-related / Basic Section 55050:Anesthesiology-related / Anesthesiology / Anesthesiology/Resuscitation studies Except Principal Investigator Emergency medicine
Keywords	Principal Investigator 低酸素応答 / キヌレン酸 / 虚血再灌流障害 / 心肺蘇生 / 敗血症性心筋症 / トリプトファン代謝 / 敗血症性心筋障害 / KATⅡ阻害剤 / 敗血症性ショック / 低酸素 … More / HIF / PHD阻害剤 / HIF-PH阻害薬 / キヌレニン経路 / 遠隔虚血プレコンディショニング / 心停止後症候群 / 心停止 … More Except Principal Investigator カリウムチャネル / Tリンパ球 / 免疫能維持 / Kv1.3 / アポトーシス / リンパ球 / 敗血症 Less

トリプトファン代謝分子メカニズムを標的とした敗血症性心筋障害の治療法開発Principal Investigator
- Principal Investigator
  
  南嶋しづか
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Gunma Institute of Public Health and Environmental Sciences
Molecular mechanisms of hypoxic response-dependent tryptophan metabolism in the treatment of SIMD (sepsis-induced myocardial dysfunction)Principal Investigator
- Principal Investigator
  
  Minamishima Shizuka
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Gunma Institute of Public Health and Environmental Sciences
A strategy for the treatment of post cardiac arrest syndrome adopting the mechanism of remote ischemic preconditioning.Principal Investigator
- Principal Investigator
  
  Minamishima Shizuka
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Keio University
Therapeutic strategy for maintenance of lymphocyte function to improve the prognosis of sepsis
- Principal Investigator
  
  SUZUKI Takeshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Tokai University
  Keio University
Hypoxic response as a new treatment of Post cardiac arrest syndromePrincipal Investigator
- Principal Investigator
  
  MINAMISHIMA Shizuka
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Keio University

All 2022 2020 2019 2017 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] 低酸素生物学の新展開【総論低酸素応答研究のこれまでとこれから】2022
- Author(s)
  南嶋　洋司
- Journal Title
  
  細胞
  
  Volume: 54 Pages: 354-355
- Data Source
  KAKENHI-PROJECT-20K09229
[Journal Article] 特集腎性貧血:HIF-PH阻害薬への期待と課題【各論】 HIF-PH阻害薬とESAの相違点 HIF-PH阻害の分子機構2022
- Author(s)
  南嶋　洋司
- Journal Title
  
  腎と透析
  
  Volume: 93 Pages: 171-177
- Data Source
  KAKENHI-PROJECT-20K09229
[Journal Article] Beta-blocker therapy preserves normal splenic T-lymphocyte numbers reduced in proportion to sepsis severity in a sepsis model2019
- Author(s)
  Suzuki T, Inoue K, Igarashi T, Kato J, Nagata H, Yamada T, Minamishima S, Morisaki H
- Journal Title
  
  Critical Care Research and Practice
  
  Volume: 8157482 Pages: 1-5
- DOI
  10.1155/2019/8157482
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11592
[Journal Article] The Effect of Epidural Anesthesia on Growth of Escherichia Coli at Pseudosurgical site: The Roles of the Lipocalin-2 Pathway.2015
- Author(s)
  Igarashi T, Suzuki T, Mori K, Inoue K, Seki H,Yamada T, Kosugi S, Minamishima S, Katori N, Sano F, Abe T, Morisaki H
- Journal Title
  
  Anesthesia & Analgesia
  
  Volume: 120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659705
[Journal Article] 一酸化窒素(NO)吸入療法2014
- Author(s)
  南嶋しづか、森崎　浩、武田純三
- Journal Title
  
  Mebio
  
  Volume: 31(2) Pages: 74-79
- Data Source
  KAKENHI-PROJECT-24659705
[Journal Article] 救急・緊急時に使用する薬剤2013
- Author(s)
  南嶋しづか
- Journal Title
  
  OPE NURSING
  
  Volume: 28(3) Pages: 299-310
- Data Source
  KAKENHI-PROJECT-24659705
[Journal Article] Sodium sulfide prevents water diffusion abnormality in the brain and improves long term outcome after cardiac arrest in mice.2012
- Author(s)
  Kida K, Minamishima S, Wang H, Ren J, Yigitkanli K, Nozari A, Mandeville JB, Liu PK, Liu CH, Ichinose F.
- Journal Title
  
  Resuscitation
  
  Volume: 83(10) Issue: 10 Pages: 1292-1297
- DOI
  10.1016/j.resuscitation.2012.02.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659705
[Presentation] 酸素濃度依存的プロリン水酸化とユビキチン-プロテアソーム系蛋白分解による低酸素応答の制御2022
- Author(s)
  南嶋　洋司
- Organizer
  第95回日本生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09229
[Presentation] 肺癌微小環境での低酸素応答と腫瘍免疫2022
- Author(s)
  南嶋　洋司
- Organizer
  第63回日本肺癌学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09229
[Presentation] HIFを介した低酸素応答の分子メカニズム2022
- Author(s)
  南嶋　洋司
- Organizer
  第46回日本鉄バイオサイエンス学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09229
[Presentation] 心停止・心肺蘇生後早期のキヌレニン経路活性化は予後を悪化させる2020
- Author(s)
  南嶋しづか、寅丸智子、伊原奈帆、森﨑　浩
- Organizer
  第67回日本麻酔科学会
- Data Source
  KAKENHI-PROJECT-17K11060
[Presentation] 心肺蘇生に100％酸素吸入は必要か？2017
- Author(s)
  南嶋しづか
- Organizer
  日本麻酔科学会
- Data Source
  KAKENHI-PROJECT-17K11060
[Presentation] 吸入一酸化窒素は心停止・心肺蘇生後マウスの予後を改善する2012
- Author(s)
  南嶋しづか、木田康太郎、徳田賢太郎、小杉志津子、武田純三、市瀬　史
- Organizer
  日本麻酔科学会　第５９回学術集会
- Place of Presentation
  兵庫県神戸市　神戸ポートピアホテル
- Data Source
  KAKENHI-PROJECT-24659705
[Presentation] ラット侵襲モデルにおいて深い吸入麻酔は炎症性サイトカイン分泌を促進する
- Author(s)
  井上　敬、五十嵐　達、鈴木武志、南嶋しづか、森﨑　浩
- Organizer
  日本麻酔科学会第61回学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-24659705
[Presentation] 内毒素血症ラットモデルにおいて深麻酔中のノルエピネフリンによる昇圧は予後を悪化させる
- Author(s)
  井上　敬、五十嵐　達、鈴木武志、南嶋しづか、関　博志、森﨑　浩
- Organizer
  日本麻酔科学会第62回学術集会
- Place of Presentation
  神戸ポートピアホテル（兵庫県神戸市）
- Year and Date
  2015-05-28 – 2015-05-30
- Data Source
  KAKENHI-PROJECT-24659705

1. MINAMISHIMA Shiszuka (20593966)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. SUZUKI Takeshi (80327600)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 加藤純悟 (40465018)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. AKIKO Kubo (50455573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAKAKO Hishiki (10338022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MAKOTO Suematsu (00206385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 井上敬 (90464932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Minamishima Shizuka 南嶋 しづか

MINAMISHIMA Shizuka 南嶋 しづか

Research Projects

Research Products

Co-Researchers

トリプトファン代謝分子メカニズムを標的とした敗血症性心筋障害の治療法開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of hypoxic response-dependent tryptophan metabolism in the treatment of SIMD (sepsis-induced myocardial dysfunction)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A strategy for the treatment of post cardiac arrest syndrome adopting the mechanism of remote ischemic preconditioning.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Therapeutic strategy for maintenance of lymphocyte function to improve the prognosis of sepsis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hypoxic response as a new treatment of Post cardiac arrest syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 低酸素生物学の新展開【総論 低酸素応答研究のこれまでとこれから】2022

Author(s)

Journal Title

Data Source

[Journal Article] 特集 腎性貧血:HIF-PH阻害薬への期待と課題 【各論】 HIF-PH阻害薬とESAの相違点 HIF-PH阻害の分子機構2022

Author(s)

Journal Title

Data Source

[Journal Article] Beta-blocker therapy preserves normal splenic T-lymphocyte numbers reduced in proportion to sepsis severity in a sepsis model2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Effect of Epidural Anesthesia on Growth of Escherichia Coli at Pseudosurgical site: The Roles of the Lipocalin-2 Pathway.2015

Author(s)

Journal Title

Data Source

[Journal Article] 一酸化窒素(NO)吸入療法2014

Author(s)

Journal Title

Data Source

[Journal Article] 救急・緊急時に使用する薬剤2013

Author(s)

Journal Title

Data Source

[Journal Article] Sodium sulfide prevents water diffusion abnormality in the brain and improves long term outcome after cardiac arrest in mice.2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] 酸素濃度依存的プロリン水酸化とユビキチン-プロテアソーム系蛋白分解による低酸素応答の制御2022

Author(s)

Organizer

Data Source

[Presentation] 肺癌微小環境での低酸素応答と腫瘍免疫2022

Author(s)

Organizer

Data Source

[Presentation] HIFを介した低酸素応答の分子メカニズム2022

Author(s)

Organizer

Data Source

[Presentation] 心停止・心肺蘇生後早期のキヌレニン経路活性化は予後を悪化させる2020

Author(s)

Organizer

Minamishima Shizuka 南嶋しづか

MINAMISHIMA Shizuka 南嶋しづか

[Journal Article] 低酸素生物学の新展開【総論低酸素応答研究のこれまでとこれから】2022

[Journal Article] 特集腎性貧血:HIF-PH阻害薬への期待と課題【各論】 HIF-PH阻害薬とESAの相違点 HIF-PH阻害の分子機構2022