Matsubara Tsutomu 松原勤

Researcher Number	20628698
Other IDs
Affiliation (Current)	2023: 大阪公立大学, 大学院医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2022: 大阪公立大学, 大学院医学研究科, 准教授 2016 – 2021: 大阪市立大学, 大学院医学研究科, 准教授 2015: 大阪市立大学, 大学院医学研究科, 講師 2014: 大阪市立大学, 医学(系)研究科(研究院), 講師
Review Section/Research Field	Principal Investigator Biological pharmacy / Pathological medical chemistry / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Pathological medical chemistry / General anatomy (including histology/embryology) / Gastroenterology / Medium-sized Section 28:Nano/micro science and related fields / Basic Section 48010:Anatomy-related
Keywords	Principal Investigator 肝星細胞 / 肝硬変 / FXR / 肝がん / 胆汁酸受容体 / 胆汁酸 / 細胞老化 / 線維化 / 慢性肝炎 / 加齢 … More / 肝線維化 / 脂肪肝炎 / 機能性ブロックポリペプチド / エラスチン / 臓器被膜 / HSD17B4 / 治療薬 … More Except Principal Investigator 肝星細胞 / 肝線維化 / 線維化 / Cytoglobin / NASH / サイトグロビン / 胆管癌 / 印刷所労働者 / 大阪市 / 抗線維化治療法 / FGF2 / 活性化 / 肝臓 / 繊維化 / ヒストンバリアント / 老化 / 脂肪肝炎 / 血小板 / 赤血球 / 加齢 / 非アルコール性脂肪肝炎 / 活性化肝星細胞 / 非アルコール性脂肪性肝炎 / TGF-β / 肝癌 / 酸化的DNA損傷 / 形質転換 / 腫瘍微小環境 / 肝がん / がん微小環境 / 血管新生 / 蛍光ナノダイヤモンド / 蛍光顕微鏡 / 温度計測 / 線虫 / 温度測定 / 光検出磁気共鳴 / C. elegans / 細胞 / 熱計測 / 細胞機能 / 生体機能 / ナノダイヤモンド / SKI / p21 / 若年 / 胆管細胞癌 / 印刷所 / 遺伝子発現 / 癌遺伝子 / 創薬 / E- cad / YAP/TAZ / 肝細胞 / 肝発がん / 細胞間相互作用 / ミトコンドリア呼吸鎖 / DNA損傷 Less

Functions of the cholangiocarcinoma suppressor gene extracted from printing company workers' samples: From cell cycle regulation to drug discovery
- Principal Investigator
  
  川村悦史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Osaka Metropolitan University
HSD17B4の新機能に着目した肝硬変治療薬の開発Principal Investigator
- Principal Investigator
  
  松原勤
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Osaka Metropolitan University
  Osaka City University
肝星細胞の初期活性化のメカニズム解明と生体外での類洞再構築ならびに人工肝への応用
- Principal Investigator
  
  池田一雄
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Osaka City University
Elucidation of irreversible switch mechanism in hepatic stellate cell activation
- Principal Investigator
  
  松原三佐子 (佐藤三佐子)
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka City University
機能性ブロックポリペプチドを用いた臓器被膜の再構築Principal Investigator
- Principal Investigator
  
  松原勤
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Osaka City University
In-vivo sub-cellular thermometry for quantitative thermal biology
- Principal Investigator
  
  藤原正澄
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 28:Nano/micro science and related fields
- Research Institution
  Okayama University
  Osaka City University
地元大阪の印刷所労働者胆管がん組織を使ったがん遺伝子の探索：創薬基盤の構築
- Principal Investigator
  
  川村悦史
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Osaka City University
Significance of hepatic stellate cell trasformation in liver cancer.
- Principal Investigator
  
  Sato-Matsubara Misako
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka City University
Role of red blood cells and platelets in the development of chronic inflammation of nonalcoholic steatohepatitis
- Principal Investigator
  
  藤井英樹
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
Functional analysis of hepatic stellate cell-expressed FXR in liver cirrhosis and carcinogenesisPrincipal Investigator
- Principal Investigator
  
  Tsutomu Matsubara
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
  Biological pharmacy
- Research Institution
  Osaka City University
Chip analysis for histone variants in activated hepatic stellate cells
- Principal Investigator
  
  Ikeda Kazuo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Osaka City University
Targeting Cytoglobin gene regulation as a promising strategy for treatment of liver fibrosis
- Principal Investigator
  
  SATO-MATSUBARA Misako
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka City University
Multiple comparative analysis of FXR-inhibitory effect on liver carcinogenesisPrincipal Investigator
- Principal Investigator
  
  Matsubara Tsutomu
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
  Pathological medical chemistry
- Research Institution
  Osaka City University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Patent

[Journal Article] Capacity of extracellular globins to reduce liver fibrosis via scavenging reactive oxygen species and promoting MMP-1 secretion2022
- Author(s)
  Hieu VN, Thuy LTT, Hai H, Dat NQ, Hoang DV, Hanh NV, Phuong DM, Hoang TH, Sawai H, Shiro Y, Sato-Matsubara M, Oikawa D, Tokunaga F, Yoshizato K, Kawada N.
- Journal Title
  
  Redox Biology
  
  Volume: 52 Pages: 0-0
- DOI
  10.1016/j.redox.2022.102286
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PUBLICLY-20H05337, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-19H03641, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21K05281, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-21K07968
[Journal Article] Hexa Histidine-Tagged Recombinant Human Cytoglobin Deactivates Hepatic Stellate Cells and Inhibits Liver Fibrosis by Scavenging Reactive Oxygen Species2021
- Author(s)
  Ninh Quoc Dat, Le Thi Thanh Thuy, Vu Ngoc Hieu, Fuminori Tokunaga, Massimo Pinzani, and Norifumi Kawada
- Journal Title
  
  Hepatology
  
  Volume: 0-0 Pages: 0-0
- DOI
  10.1002/hep.31752
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-20H05337, KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-18K07952, KAKENHI-PROJECT-19K22541, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-19H03641, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-16H06276
[Journal Article] Wide-field fluorescent nanodiamond spin measurements toward real-time large-area intracellular thermometry2021
- Author(s)
  Yushi Nishimura, Keisuke Oshimi, Yumi Umehara, Yuka Kumon, Kazu Miyaji, Hiroshi Yukawa, Yutaka Shikano, Tsutomu Matsubara, Masazumi Fujiwara, Yoshinobu Baba, Yoshio Teki
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Pages: 4248-4248
- DOI
  10.1038/s41598-021-83285-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21935, KAKENHI-PROJECT-19K14636, KAKENHI-PROJECT-20H00335, KAKENHI-PROJECT-19K15422
[Journal Article] Stress can attenuate hepatic lipid accumulation via elevation of hepatic β-muricholic acid levels in mice with nonalcoholic steatohepatitis.2021
- Author(s)
  Sayuri Takada, Tsutomu Matsubara, Hideki Fujii, Misako Sato-Matsubara, Atsuko Daikoku, Naoshi Odagiri, Yuga Amano-Teranishi, Norifumi Kawada, Kazuo Ikeda
- Journal Title
  
  Lab Invest.
  
  Volume: 101 Pages: 193-203
- DOI
  10.1038/s41374-020-00509-x
- NAID
  120007147938
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07952, KAKENHI-PROJECT-21K07968
[Journal Article] Anti-fibrotic treatments for chronic liver diseases: The present and the future2021
- Author(s)
  Naoshi Odagiri, Tsutomu Matsubara, Misako Sato-Matsubara, Hideki Fujii, Masaru Enomoto, Norifumi Kawada
- Journal Title
  
  Clin Mol Hepatol.
  
  Volume: - Pages: 413-424
- DOI
  10.3350/cmh.2020.0187
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07952, KAKENHI-PROJECT-19K23951, KAKENHI-PROJECT-21H02626, KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-20K16967
[Journal Article] TGF-β-driven reduction of cytoglobin is associated with oxidative DNA damage of stellate cells in non-alcoholic steatohepatitis2020
- Author(s)
  Yoshinori Okina, Misako Sato-Matsubara, Tsutomu Matsubara, Atsuko Daikoku, Lisa Longato, Krista Rombouts, Le Thi Thanh Thuy, Hiroshi Ichikawa, Yukiko Minamiyama, Mitsutaka Kadota, Hideki Fujii, Masaru Enomoto, Kazuo Ikeda, Katsutoshi Yoshizato, Massimo Pinzani, Norifumi Kawada
- Journal Title
  
  Journal of Hepatology
  
  Volume: -
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18012
[Journal Article] TGF-β1-driven reduction of cytoglobin leads to oxidative DNA damage in stellate cells during non-alcoholic steatohepatitis.2020
- Author(s)
  Yoshinori Okina, Misako Sato-Matsubara, Tsutomu Matsubara, Atsuko Daikoku, Lisa Longato, Krista Rombouts, Le Thi Thanh Thuy, Hiroshi Ichikawa5, Yukiko Minamiyama6, Mitsutaka Kadota7, Hideki Fujii, Masaru Enomoto, Kazuo Ikeda, Katsutoshi Yoshizato, Massimo Pinzani, and Norifumi Kawada
- Journal Title
  
  Journal of hepatology
  
  Volume: - Pages: 882-895
- DOI
  10.1016/j.jhep.2020.03.051
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07952, KAKENHI-PROJECT-19K08428
[Journal Article] Association between HLA-DQA1/DRB1 polymorphism and development of hepatocellular carcinoma during entecavir treatment.2019
- Author(s)
  Ritsuzo Kozuka, Masaru Enomoto, Misako Sato‐Matsubara, Kanako Yoshida, Hiroyuki Motoyama, Atsushi Hagihara, Hideki Fujii, Sawako Uchida‐Kobayashi, Hiroyasu Morikawa, Akihiro Tamori, Norifumi Kawada, Yoshiki Murakami
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: - Pages: 937-946
- DOI
  10.1111/jgh.14454
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08649, KAKENHI-PROJECT-18K07952
[Journal Article] Adrenoceptor-stimulated inflammatory response in stress-induced serum amyloid A synthesis2019
- Author(s)
  Konstandi Maria、Sotiropoulos Ioannis、Matsubara Tsutomu、Malliou Foteini、Katsogridaki Alexandra、Andriopoulou Christina E.、Gonzalez Frank J.
- Journal Title
  
  Psychopharmacology
  
  Volume: ー
- DOI
  10.1007/s00213-018-5149-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18012
[Journal Article] Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells.2019
- Author(s)
  Odagiri Naoshi、Matsubara Tsutomu、Higuchi Moe, Takada Sayuri, Urushima Hayato, Sato-Matsubara Misako, Teranishi Yuga, Yoshizato Katsutoshi, Kawada Norifumi, Ikeda Kazuo.
- Journal Title
  
  Molecular and Cellular Biochemistry
  
  Volume: 455(1-2) Pages: 7-19
- DOI
  10.1007/s11010-018-3466-x
- NAID
  120006847891
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18012, KAKENHI-PROJECT-16H05290, KAKENHI-PROJECT-16K08472, KAKENHI-PROJECT-16K19362, KAKENHI-PROJECT-18K07952
[Journal Article] 肝星細胞の活性化の仕組み、サイトグロビンの作用から見えてくる新しい視点2019
- Author(s)
  松原三佐子、吉里則文、河田則文
- Journal Title
  
  細胞
  
  Volume: 51 Pages: 530-534
- Data Source
  KAKENHI-PROJECT-18K07952
[Journal Article] New player in tumor-stromal interaction: Granulin as a novel therapeutic target for pancreatic ductal adenocarcinoma liver metastasis.2017
- Author(s)
  2.Sato-Matsubara M, Kawada N.
- Journal Title
  
  Hepatology
  
  Volume: 65 Pages: 374-374
- DOI
  10.1002/hep.28849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08314
[Journal Article] Fibroblast growth factor 2 (FGF2) regulates cytoglobin expression and activation of human hepatic stellate cells via JNK signaling.2017
- Author(s)
  Sato-Matsubara Misako、Matsubara Tsutomu、Daikoku Atsuko、Okina Yoshinori、Longato Lisa、Rombouts Krista、Thuy Le Thi Thanh、Adachi Jun、Tomonaga Takeshi、Ikeda Kazuo、Yoshizato Katsutoshi、Pinzani Massimo、Kawada Norifumi
- Journal Title
  
  J Biol Chem.
  
  Volume: 292 Pages: 18961-18972
- DOI
  10.1074/jbc.m117.793794
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08472, KAKENHI-PROJECT-16K19363, KAKENHI-PROJECT-15K08314
[Journal Article] Genome-wide association study identifies 1 a TLL1 variant associated with development of hepatocellular carcinoma after eradication of hepatitis C virus.2017
- Author(s)
  Matsuura K, Honda M, et al.
- Journal Title
  
  Gastroenterology
  
  Volume: - Pages: 1383-1394
- DOI
  10.1053/j.gastro.2017.01.041
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-16H05285, KAKENHI-PROJECT-15K15285, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-15K08986, KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-15K09019, KAKENHI-PROJECT-16K09335, KAKENHI-PROJECT-17K09457, KAKENHI-PROJECT-15K08077, KAKENHI-PROJECT-15K08314
[Journal Article] 肝線維化進展の分子機構2016
- Author(s)
  松原　三佐子、　河田則文
- Journal Title
  
  肝胆膵
  
  Volume: 73巻6号 Pages: 873-873
- Data Source
  KAKENHI-PROJECT-15K08314
[Journal Article] Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism2015
- Author(s)
  Teranishi Y, Matsubara T, Krausz KW, Le TT, Gonzalez FJ, Yoshizato K, Ikeda K, Kawada N
- Journal Title
  
  Lab Invest
  
  Volume: 95 Pages: 515-524
- DOI
  10.1038/labinvest.2015.29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670589, KAKENHI-PROJECT-26870501
[Journal Article] Adipocyte-specific disruption of fat-specific protein 27 causes hepatosteatosis and insulin resistance in high-fat diet-fed mice2015
- Author(s)
  Tanaka N, Takahashi S, Matsubara T, Jiang C, Sakamoto W, Chanturiya T, Teng R, Gavrilova O, Gonzalez FJ
- Journal Title
  
  J Biol Chem
  
  Volume: 印刷中
- DOI
  10.1074/jbc.m114.605980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26870501
[Journal Article] Role of white adipose lipolysis in the development of NASH induced by methionine- and choline-deficient diet2014
- Author(s)
  Tanaka N, Takahashi S, Fang ZZ, Matsubara T, Krausz KW, Qu A, Gonzalez FJ.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1841 Pages: 1596-1607
- DOI
  10.1016/j.bbalip.2014.08.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26870501
[Patent] 還流培養装置および還流培養システム2020
- Inventor(s)
  吉里勝利、松原三佐子、坪田佳代
- Industrial Property Rights Holder
  吉里勝利、松原三佐子、坪田佳代
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18K07952
[Patent] 胆道癌又は膵癌治療剤2019
- Inventor(s)
  川村　悦史、松原　勤、河田　則文、池田　一雄
- Industrial Property Rights Holder
  川村　悦史、松原　勤、河田　則文、池田　一雄
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-207404
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K10604
[Patent] 抗線維化剤2017
- Inventor(s)
  松原　勤、池田　一雄、河田　則文、松原　三佐子
- Industrial Property Rights Holder
  松原　勤、池田　一雄、河田　則文、松原　三佐子
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Acquisition Date
  2017
- Data Source
  KAKENHI-PROJECT-15K08314
[Patent] 特許権2015
- Inventor(s)
  河田　則文, 松原　三佐子
- Industrial Property Rights Holder
  河田　則文, 松原　三佐子
- Industrial Property Rights Type
  特許
- Filing Date
  2015-04-06
- Acquisition Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-15K08314
[Presentation] アセトアミノフェン誘発急性肝炎におけるC/EBP homologous proteinの役割2022
- Author(s)
  樋口萌、松原勤、湯浅秀人、宇留島隼人、池田一雄
- Organizer
  第127回　日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-21H02626
[Presentation] アセトアミノフェン誘発急性肝炎におけるC/EBP homologous proteinの役割2022
- Author(s)
  樋口萌、松原勤、湯浅秀人、宇留島隼人、池田一雄
- Organizer
  第127回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-21K06757
[Presentation] 肝星細胞の活性化時における上皮-間葉転換と機能変化との相関2022
- Author(s)
  宇留島隼人、和氣健二郎、湯浅秀人、松原勤、池田一雄
- Organizer
  第127回　日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-21H02626
[Presentation] 肝星細胞の微小突起形成におけるCdc42の役割について2022
- Author(s)
  湯浅秀人、宇留島隼人、松原勤、池田一雄
- Organizer
  第127回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-21K06757
[Presentation] 肝星細胞の微小突起形成におけるCdc42の役割ついて2022
- Author(s)
  湯浅秀人、宇留島隼人、松原勤、池田一雄
- Organizer
  第127回　日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-21H02626
[Presentation] Intracellular gap formation of the liver sinusoidal endothelial cells facilitates the liver metastasis ability of cancer cell2021
- Author(s)
  Truong Huu Hoang, Misako Sato-Matsubara, Yuasa Hideto, Tsutomu Matsubara, Hayato Urushima, Le Thi Thanh Thuy, Atsuko Daikoku, Yoshinori Okina, Akihiro Tamori, Katsutoshi Yoshizato, Norifumi Kawada
- Organizer
  American Association for Cancer Research (AACR) Annual Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07968
[Presentation] 肝星細胞と肝実質細胞との相関関係2021
- Author(s)
  和氣健二郎、宇留島隼人、湯浅秀人、松原勤、池田一雄
- Organizer
  第35回　肝類洞壁細胞研究会
- Data Source
  KAKENHI-PROJECT-21H02626
[Presentation] 肝細胞と肝星細胞との細胞膜を介した直接的なクロストーク2021
- Author(s)
  井上喜来々、松原三佐子、Truong Huu Hoang、松原勤、宇留島隼人、湯浅秀人、大黒敦子、池田一雄、吉里勝利、河田則文
- Organizer
  第28回　肝細胞研究会
- Data Source
  KAKENHI-PROJECT-20H00335
[Presentation] Cell membrane-mediated direct crosstalks between hepatocytes and HSCs2021
- Author(s)
  Kirara Inoue, Misako Sato-Matsubara, Truong Huu Hoang, Tsutomu Matsubara, Hayato Urushima, Atsuko Daikoku, Kazuo Ikeda, Katsutoshi Yoshizato, Norifumi Kawada
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference 2021 Osaka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07968
[Presentation] Cytoglobin欠損マウスの肝星細胞に由来する一酸化窒素は肝細胞のミトコンドリア機能障害を引き起こす2021
- Author(s)
  翁良徳、松原三佐子、宇留島隼人、松原勤、池田一雄、吉里勝利、河田則文
- Organizer
  第35回　肝類洞壁細胞研究会
- Data Source
  KAKENHI-PROJECT-21H02626
[Presentation] 肝細胞と肝星細胞との細胞膜を介した直接的なクロストーク2021
- Author(s)
  井上喜来々、松原三佐子、Truong Huu Hoang、松原勤、宇留島隼人、湯浅秀人、大黒敦子、池田一雄、吉里勝利、河田則文
- Organizer
  肝細胞研究会
- Data Source
  KAKENHI-PROJECT-21K07968
[Presentation] 肝星細胞の微小突起形成機構について2021
- Author(s)
  湯浅秀人，宇留島隼人，松原勤，池田一雄
- Organizer
  第35回　肝類洞壁細胞研究会
- Data Source
  KAKENHI-PROJECT-21H02626
[Presentation] 肝細胞と肝星細胞との細胞膜を介した直接的なクロストーク2021
- Author(s)
  井上喜来々、松原三佐子、Truong Huu Hoang、松原勤、宇留島隼人、湯浅秀人、大黒敦子、池田一雄、吉里勝利、河田則文
- Organizer
  第28回　肝細胞研究会
- Data Source
  KAKENHI-PROJECT-20K21907
[Presentation] Cell membrane-mediated direct crosstalks between hepatocytes and HSCs2021
- Author(s)
  Kirara Inoue, Misako Sato-Matsubara, Truong Huu Hoang, Tsutomu Matsubara, Hayato Urushima, Atsuko Daikoku, Kazuo Ikeda, Katsutoshi Yoshizato, Norifumi Kawada
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference 2021 Osaka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00335
[Presentation] 臨床検体から抽出した癌抑制遺伝子SKIによる肝胆癌細胞周期の抑制2021
- Author(s)
  川村悦史、松原勉、大黒敦子、武藤芳美、高田さゆり、新川寛二、木下正彦、小田桐直志、小谷晃平、元山宏行、小塚立蔵、松原三佐子、萩原淳司、藤井英樹、打田佐和子、田中肖吾、竹村茂一、榎本大、田守昭博、久保正二、池田一雄、河田則文
- Organizer
  第44回　日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-21K07968
[Presentation] 肝脂質の恒常性維持における臓器ネットワーク2021
- Author(s)
  松原　勤
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K21907
[Presentation] Cell membrane-mediated direct crosstalks between hepatocytes and HSCs2021
- Author(s)
  Kirara Inoue, Misako Sato-Matsubara, Truong Huu Hoang, Tsutomu Matsubara, Hayato Urushima, Atsuko Daikoku, Kazuo Ikeda, Katsutoshi Yoshizato, Norifumi Kawada
- Organizer
  Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference 2021 Osaka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21907
[Presentation] Cytoglobin欠損マウスの肝星細胞に由来する一酸化窒素は肝細胞のミトコンドリア機能障害を引き起こす2021
- Author(s)
  翁良徳、松原三佐子、宇留島隼人、松原勤、池田一雄、吉里勝利、河田則文
- Organizer
  第35回　肝類洞壁細胞研究会
- Data Source
  KAKENHI-PROJECT-21K07968
[Presentation] 肝星細胞の微小突起形成機構について2021
- Author(s)
  湯浅秀人、宇留島隼人、松原勤、池田一雄
- Organizer
  第35回肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-21K06757
[Presentation] 上皮－間葉転換に着目した新規肝星細胞脱活性化候補化合物の探索2021
- Author(s)
  宇留島隼人、松原勤、湯浅秀人、和氣健二郎、池田一雄
- Organizer
  第35回　肝類洞壁細胞研究会
- Data Source
  KAKENHI-PROJECT-21H02626
[Presentation] Intracellular gap formation of the liver sinusoidal endothelial cells facilitates the liver metastasis ability of cancer cells2021
- Author(s)
  Truong Huu Hoang, Misako Sato-Matsubara, Yuasa Hideto, Tsutomu Matsubara, Hayato Urushima, Le Thi Thanh Thuy, Atsuko Daikoku, Yoshinori Okina, Akihiro Tamori, Katsutoshi Yoshizato, Norifumi Kawada
- Organizer
  American Association for the Study of Liver Diseases (AASLD) The Liver Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07968
[Presentation] Intracellular gap formation of the liver sinusoidal endothelial cells facilitates the liver metastasis ability of cancer2020
- Author(s)
  チュンフーホアン、松原三佐子、湯浅秀人、松原勤、宇留島隼人、リーツイ、大黒敦子、翁良徳、吉里勝利、河田則文
- Organizer
  第34回　肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] NASHおよび肝がん研究の最前線」NASH肝線維化進展におけるCYGBの細胞防御機構の解明2020
- Author(s)
  松原三佐子
- Organizer
  第27回　肝細胞研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] 広領域マイクロ波照射が可能な細胞培養ディッシュの開発2020
- Author(s)
  押味佳裕、西村勇姿、田中益明、仕幸英治、松原勤、藤原正澄、手木芳男
- Organizer
  量子生命科学会第2回大会
- Data Source
  KAKENHI-PROJECT-20H00335
[Presentation] NAFLD/NASHの肝線維化進展におけるCYGB依存的酸化ストレス応答と発現制御機構の解明2020
- Author(s)
  翁良徳、松原三佐子、河田則文
- Organizer
  第56回　日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] 職業性肝内胆管癌組織を使った癌遺伝子の探索2020
- Author(s)
  川村悦史、松原勤、伊藤得路、湯浅秀人、宇留島隼人、松原三佐子、萩原淳司、藤井英樹、木下正彦、打田佐和子、田中肖吾、竹村茂一、榎本大、田守昭博、久保正二、祝迫惠子、村上善基、田口善弘、池田一雄、河田則文
- Organizer
  日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-19K10604
[Presentation] 核酸アナログによるHBV制御後のHLA-SNPを用いた肝癌サーベイランスについて2020
- Author(s)
  小塚立蔵、榎本大、松原三佐子、河田則文
- Organizer
  第56回　日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] Genetic search started from resected samples of juvenile-onset human cholangiocarcinoma: SKI interacts with microRNA-3648 resulting in cell cycle regulation2020
- Author(s)
  川村悦史、松原勤、出口早苗、樋口萌、高田さゆり、大黒敦子、伊藤得路、木下正彦、松原三佐子、小田桐直志、田中肖吾、竹村茂一、村上善基、榎本大、田守昭博、久保正二、祝迫惠子、池田一雄、河田則文
- Organizer
  アジア太平洋肝臓学会（APASL）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10604
[Presentation] 職業性肝内胆管癌組織を使った癌遺伝子の探索2020
- Author(s)
  川村悦史、松原勤、伊藤得路、湯浅秀人、宇留島隼人、松原三佐子、萩原淳司、藤井英樹、木下正彦、打田佐和子、田肖吾、竹村茂一、榎本大、田守昭博、久保正二、祝迫惠子、村上善基、田口善弘、池田一雄、河田則文
- Organizer
  第56回　日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] 肝硬変治療薬開発を見据えた肝星細胞活性化抑制物質の同定2020
- Author(s)
  松原三佐子、河田則文
- Organizer
  第56回　日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] 若年胆管癌組織を使った癌抑制遺伝子の探索2019
- Author(s)
  川村悦史, 松原勤, 樋口萌, 出口早苗, 高田さゆり, 大黒敦子, 伊藤得路, 木下正彦, 松原三佐子, 小田桐直志, 田中肖吾, 竹村茂一, 村上善基, 榎本大, 田守昭博, 久保正二, 祝迫惠子, 池田一雄, 河田則文
- Organizer
  第43回日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] Search for novel component with ability to suppress the hepatic stellate cell activation in AHCC.2019
- Author(s)
  Takayama M, Urushima H, Yuasa H, Matsubara T, Ikeda K.
- Organizer
  27th International Congress on Nutrition and Integrative Medicine
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] Histological Evaluations after Achieving a Sustained Virologic Response to DirectActing Antiviral Treatment for Chronic Hepatitis C in a Short Term2019
- Author(s)
  Masaru Enomoto, Yutaka Yasui, Misako Sato-Matsubara, Yoshihiro Ikura, Akihiro Tamori, Ritsuzo Kozuka, Etsushi Kawamura, Atsushi Hagihara, Hideki Fujii1, Sawako Uchida-Kobayashi, Yoshiki Murakami, Norifumi Kawada
- Organizer
  JSH international Liver Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] 非アルコール性脂肪性肝炎におけるCytoglobin発現制御機構2019
- Author(s)
  翁良徳、松原三佐子、松原勤、大黒敦子、池田一雄、吉里勝利、河田則文
- Organizer
  肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] 肝硬変時の低ナトリウム血症による低浸透圧環境が門脈圧亢進に及ぼす影響2019
- Author(s)
  宇留島隼人, 松原勤, 湯浅秀人, 河田則文, 池田一雄
- Organizer
  第26回日本門脈圧亢進症学会総会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] LawsoneはヒトCYGB遺伝子発現誘導作用を持つ抗線維化化合物である2019
- Author(s)
  大黒敦子、松原勤、松原三佐子、池田一雄、河田則文
- Organizer
  第43回　日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] 直接的細胞接着に依存する肝細胞と星細胞の緊密な相互作用2019
- Author(s)
  松原三佐子、谷口絵美、松原勤、宇留島隼人、大黒敦子、森浦芳枝、門野千穂、池田一雄、和氣健二郎、河田則文、吉里勝利
- Organizer
  第26回　肝細胞研究会
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] Downregulation of Cytoglobin by TGF-β Leads to Hydroxyl Radical-induced Oxidative DNA Damage in Human HSCs.2019
- Author(s)
  Yoshinori Okina, Misako Sato-Matsubara, Tsutomu Matsubara, Atsuko Daikoku, Hideki Fujii, Kazuo Ikeda, Katsutoshi Yoshizato, Massimo Pinzani, Norifumi Kawada
- Organizer
  JSH international Liver Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] 肝細胞-肝星細胞間の接着結合喪失は肝星細胞活性化に寄与する2019
- Author(s)
  宇留島隼人, 湯浅秀人, 松原勤, 井上孝二, 和氣健二郎, 佐藤哲二, 池田一雄
- Organizer
  第124回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] マウス脂肪肝炎モデルにおける加齢の影響2019
- Author(s)
  藤井英樹、松原三佐子、河田則文
- Organizer
  第55回　日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] NAFLD/NASHの病態進展における血清胆汁酸組成の影響2019
- Author(s)
  藤井英樹, 松原勤, 河田則文
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] LawsoneはヒトCYGB遺伝子発現誘導作用を持つ抗線維化化合物である2019
- Author(s)
  大黒敦子、松原勤、松原三佐子、池田一雄、河田則文
- Organizer
  第26回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] 正常肝ないし障害肝の肝星細胞におけるfilopodia関連タンパク質の発現解析2019
- Author(s)
  湯浅秀人、宇留島隼人、松原勤、池田一雄
- Organizer
  第33回肝類洞壁細胞研究会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] 四塩化炭素投与ラット肝炎モデルにおける肝星細胞活性化の検討2019
- Author(s)
  原矢委子、黒田範行、井上孝二、松原勤、宇留島隼人、池田一雄、和氣健二郎、佐藤哲二
- Organizer
  第124回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-16K08472
[Presentation] TGF-β1 transcriptionally repressed cytoglobin expression and enhanced H2O2-induced oxidative DNA damage in activated HSCs.2019
- Author(s)
  Misako Sato-Matsubara, Yoshinori Okina, Tsutomu Matsubara, Atsuko Daikoku1, Krista Rombouts, Le Thi Thanh Thuy, Hideki Fujii1, Kazuo Ikeda, Katsutoshi Yoshizato, Massimo Pinzani, and Norifumi Kawada
- Organizer
  JSH international Liver Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] 病態進展におけるCYGB保護作用の分子機序解析2019
- Author(s)
  松原三佐子、翁良徳、松原勤、池田一雄、吉里勝利、河田則文
- Organizer
  第51回日本臨床分子形態学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] TGF-βとサイトグロビンの拮抗作用はヒトNASHにおける星細胞活性化と肝線維化に影響する2019
- Author(s)
  翁良徳、松原三佐子、藤井英樹、河田則文
- Organizer
  第55回　日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] 肝がん・肝硬変における肝星細胞の多面的理解2019
- Author(s)
  松原勤
- Organizer
  第33回肝類洞壁細胞研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] 肝細胞―肝星細胞間の接着結合喪失は肝星細胞活性化に寄与する2019
- Author(s)
  宇留島隼人、湯浅秀人、松原勤、井上孝二、和氣健二郎、佐藤哲二、池田一雄
- Organizer
  第124回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-16K08472
[Presentation] 若年胆管癌組織を使った癌抑制遺伝子の探索2019
- Author(s)
  川村悦史、松原勤、出口早苗、樋口萌、高田さゆり、大黒敦子、伊藤得路、木下正彦、松原三佐子、小田桐直志、田中肖吾、竹村茂一、村上善基、榎本大、田守昭博、久保正二、祝迫惠子、池田一雄、河田則文
- Organizer
  日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-19K10604
[Presentation] Identification of Lawsone as an Anti-fibrotic Agent based on High-Throughput Screening System with Human COL1A2 Promoter Activity.2019
- Author(s)
  Misako Sato-Matsubara, Tsutomu Matsubara, Atsuko Daikoku, Kazuo Ikeda, Katsutoshi Yoshizato, Norifumi Kawada
- Organizer
  JSH international Liver Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] マウス脂肪肝炎モデルにおける加齢の影響2019
- Author(s)
  藤井英樹、松原三佐子、河田則文
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17K09437
[Presentation] Oligonol ameliorates hepatic fibrosis through the inhibition of FAK-YAP pathway in hepatic stellate cells.2019
- Author(s)
  Urushima H, Yuasa H, Takayama M, Matsubara T, Ikeda K.
- Organizer
  27th International Congress on Nutrition and Integrative Medicine
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] TGF-β1 transcriptionally repressed cytoglobin expression and enhanced H2O2-induced oxidative DNA damage in activated HSCs.2019
- Author(s)
  Sato-Matsubara M, Okina Y, Matsubara T, Daikoku A, Rombouts K, Thuy LTT, Fujii H, Ikeda K, Yoshizato K, Pinzani M, Kawada N.
- Organizer
  20th International Symposium on Cells of Hepatic Sinusoid
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] Downregulation of cytoglobin by TGF-β leads to hydroxyl radical-induced oxidative DNA damage in human HSCs.2019
- Author(s)
  Okina Y, Sato-Matsubara M, Matsubara T, Daikoku A, Rombouts K, Fujii H, Ikeda K, Pinzani M, Kawada N.
- Organizer
  JSH:International Liver Conference 2019
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] 肝線維老化肝星細胞におけるTGFβシグナルの変化2019
- Author(s)
  松原勤、高田さゆり、小田桐直志、宇留島隼人、河田則文、池田一雄
- Organizer
  第125回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] 老化肝星細胞におけるTGF-βシグナル変化の分子機序解析2019
- Author(s)
  松原勤、高田さゆり、小田桐直志、松原三佐子、大黒敦子、宇留島隼人、吉里勝利、河田則文、池田一雄
- Organizer
  第26回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] 肝星細胞活性化と肝障害　シンポジウム；肝臓、最新の話題と理論2019
- Author(s)
  池田一雄、松原勤、宇留島隼人、湯浅秀人
- Organizer
  第124回日本解剖学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08472
[Presentation] Stellate cells initiate the activation by the loss of adherence junction with hepatocytes.2019
- Author(s)
  Urushima H, Yuasa H, Matsubara T, Hara Y, Inoue K, Wake K, Sato T, Ikeda K.
- Organizer
  20th International Symposium on Cells of Hepatic Sinusoid
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] 非アルコール性脂肪性肝炎におけるCytoglobin発現制御機構2019
- Author(s)
  翁良徳、松原三佐子、松原勤、大黒敦子、池田一雄、吉里勝利、河田則文
- Organizer
  第33回肝類洞壁細胞研究会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] 若年胆管癌組織を使った癌抑制遺伝子の探索2019
- Author(s)
  川村悦史、松原勤、出口早苗、樋口萌、高田さゆり、大黒敦子、伊藤得路、木下正彦、松原三佐子、小田桐直志、田中肖吾、竹村茂一、村上善基、榎本大、田守昭博、久保正二、祝迫惠子、池田一雄、河田則文
- Organizer
  第26回　肝細胞研究会
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] 老化肝星細胞におけるTGFβシグナル変化についての解析2019
- Author(s)
  高田さゆり, 松原勤, 樋口萌, 小田桐直志, 松原三佐子, 河田則文, 池田一雄
- Organizer
  第43回日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] 肝線維化病態進展におけるCYGB保護作用の分子機序解析2019
- Author(s)
  松原三佐子、翁良徳、松原勤、池田一雄、吉里勝利、河田則文
- Organizer
  日本臨床分子形態学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07952
[Presentation] 直接的細胞接着に依存する肝細胞と星細胞の緊密な相互作用2019
- Author(s)
  松原三佐子、谷口絵美、松原勤、宇留島隼人、大黒敦子、森浦芳枝、門野千穂、池田一雄、和氣健二郎、河田則文、吉里勝利
- Organizer
  第26回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] TGFβ1 reduces Cytoglobin expression via Smad2-SP3 pathway in human, but not mouse, hepatic stellate cells2018
- Author(s)
  Sato-Matsubara M, Okina Y, Matsubara T, Daikoku A, Fujii H, Rombouts K, Ikeda K, Yoshizato K, Pinzani M, Kawada N.
- Organizer
  AASLD single topic conference; Hepatic fibrosis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] 肝細胞と肝星細胞の共培養による肝星細胞の活性化抑制2018
- Author(s)
  松原三佐子, 松原勤, 宇留島隼人, 大黒敦子, 森浦芳枝, 門野千穂, 池田一雄, 河田則文, 吉里勝利
- Organizer
  第25回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] ヒト肝星細胞における老化関連分泌因子の遺伝子発現解析2018
- Author(s)
  松原勤　小田桐直志　河田則文　池田一雄
- Organizer
  第123回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] 脂肪性肝炎の進展におけるCYGB保護作用の分子機序解析2018
- Author(s)
  松原三佐子, 翁良徳, 松原勤, 大黒敦子, 池田一雄, 吉里勝利, 河田則文
- Organizer
  第32回肝類洞壁細胞研究会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] 肝星細胞のspineを介した肝細胞との接着の意義2018
- Author(s)
  宇留島隼人、松原勤、井上孝二、和氣健二郎、佐藤哲二、池田一雄
- Organizer
  第123回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-16K08472
[Presentation] ヒト肝星細胞における老化関連分泌因子の遺伝子発現解析2018
- Author(s)
  松原勤、小田桐直志、河田則文、池田一雄
- Organizer
  第123回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-16K08472
[Presentation] 肝細胞-肝星細胞間接着と星細胞活性化との関連2018
- Author(s)
  宇留島隼人, 松原勤, 湯浅秀人, 井上孝二, 和氣健二郎, 佐藤哲二, 池田一雄
- Organizer
  第32回肝類洞壁細胞研究会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] ヒト肝星細胞における脱活性化誘導制御機構の解明2018
- Author(s)
  松原三佐子, 大黒敦子, 松原勤, 池田一雄, 吉里勝利, 河田則文
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] 肝星細胞の細胞老化に伴う遺伝子発現変化2017
- Author(s)
  松原勤　小田桐直志　樋口萌　河田則文　池田一雄
- Organizer
  第24回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] ヒト肝星細胞におけるTGF-β1/Smadシグナルを介したCytoglobin発現制御機構2017
- Author(s)
  翁良徳,松原三佐子,河田則文
- Organizer
  第21回日本肝臓学会大会(JDDW2017)
- Data Source
  KAKENHI-PROJECT-15K08314
[Presentation] 肝星細胞を標的とした細胞表面抗原の樹立2017
- Author(s)
  吹田安佐詠, 松原三佐子, 松原勤, 池田一雄, 河田則文
- Organizer
  第53回日本肝臓学会総会(広島)
- Data Source
  KAKENHI-PROJECT-15K08314
[Presentation] 肝星細胞の細胞老化に伴う遺伝子発現変化2017
- Author(s)
  松原勤　小田桐直志　樋口萌　河田則文　池田一雄
- Organizer
  第24回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-26870501
[Presentation] 肝星細胞を標的とした抗線維化治療薬の開発2017
- Author(s)
  松原三佐子, 翁良徳, 河田則文
- Organizer
  第53回日本肝臓学会総会(広島)
- Data Source
  KAKENHI-PROJECT-15K08314
[Presentation] ヒト肝星細胞の老化関連分泌表現型解析2017
- Author(s)
  小田桐直志　松原勤　河田則文　池田一雄
- Organizer
  第31回肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-17K18012
[Presentation] ヒト老化肝星細胞の遺伝子発現解析2016
- Author(s)
  小田桐直志、松原勤、河田則文、池田一雄
- Organizer
  第30回肝類洞壁細胞研究会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-26870501
[Presentation] ヒト老化肝星細胞の遺伝子発現解析2016
- Author(s)
  小田桐直志、松原勤、河田則文、池田一雄
- Organizer
  第30回肝類洞壁細胞研究会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-16K08472
[Presentation] 肝星細胞の脱活性化を誘導するサイトグロビン発現促進機構の解明2016
- Author(s)
  松原三佐子、大黒敦子、松原勤、池田一雄、河田則文
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ幕張　（千葉県千葉市）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K08314
[Presentation] 肝星細胞の遺伝子発現における胆汁酸の影響2016
- Author(s)
  松原勤、寺西優雅、小田桐直志、河田則文、池田一雄
- Organizer
  第23回肝細胞研究会
- Place of Presentation
  大阪大学中之島センター（大阪府大阪市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-26870501
[Presentation] FGF2はCytoglobinとSMA遺伝子発現を制御し肝星細胞の脱活性化を促進する2016
- Author(s)
  松原三佐子、大黒敦子、松原勤、池田一雄、河田則文
- Organizer
  第23回肝細胞研究会
- Place of Presentation
  大阪大学中之島センター　（大阪府大阪市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-15K08314
[Presentation] 肝臓細胞の皮質への接着反応の解析2016
- Author(s)
  吉里勝利、松原三佐子
- Organizer
  第23回肝細胞研究会
- Place of Presentation
  大阪大学中之島センター　（大阪府大阪市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-15K08314
[Presentation] ヒト肝星細胞におけるFGF2のCytoglobin遺伝子発現制御2016
- Author(s)
  松原三佐子、大黒敦子、松原勤、池田一雄、河田則文
- Organizer
  第３０回間類洞壁細胞研究会学術集会
- Place of Presentation
  富山国際会議場　（富山県富山市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-15K08314
[Presentation] 肝星細胞におけるTGF-β１のCYGB発現抑制機構の解析2016
- Author(s)
  翁良徳、松原三佐子、松原勤、大黒敦子、池田一雄、吉里勝利、河田則文
- Organizer
  第23回肝細胞研究会
- Place of Presentation
  大阪大学中之島センター　（大阪府大阪市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-15K08314
[Presentation] Identification of FGF2 as a cytoglobin regulatory factor leading to the deactivation of human hepatic stellate cells2015
- Author(s)
  Misako Sato-Matsubara, Tsutomu Matsubara, Atsuko Daikoku, Krista Rombouts, Kazuo Ikeda, Massimo Pinzani, Norifumi Kawada
- Organizer
  AASLD 2015
- Place of Presentation
  San Francisco, California
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08314
[Presentation] FGF2 deactivates human hepatic stellate cells following induction of cytoglobin and down-regulation of αSMA expressions2015
- Author(s)
  Misako Sato-Matsubara, Tsutomu Matsubara, Atsuko Daikoku, Krista Rombouts, Kazuo Ikeda, Massimo Pinzani, Norifumi Kawada
- Organizer
  ISHSR 2015, 18th International Symposium on Cells of the Hepatic Sinusoid
- Place of Presentation
  Asilomoar, California
- Year and Date
  2015-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08314
[Presentation] ヒト肝星細胞におけるサイトグロビン遺伝子発現調節機構の分子機序解析2015
- Author(s)
  松原　三佐子、大黒　敦子、松原　勤、池田　一雄、河田　則文
- Organizer
  第41回日本肝臓学会西部会
- Place of Presentation
  名古屋、名古屋国際会議場
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K08314
[Presentation] 肝星細胞によるサイトグロビンの発現に対する酸素分圧と基底膜成分の影響2015
- Author(s)
  沖田大和、松原勤、池田一雄、河田則文
- Organizer
  第41回日本肝臓学会西部会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26870501
[Presentation] 肝星細胞正常性維持へのサイトグロビン (cytoglobin)　の関与2015
- Author(s)
  沖田大和、井石契子、松原勤、池田一雄、河田則文、吉里勝利
- Organizer
  第22回肝細胞研究会
- Place of Presentation
  米子コンベンションセンター(鳥取県米子市)
- Year and Date
  2015-06-04
- Data Source
  KAKENHI-PROJECT-26870501
[Presentation] Inhibitory effect of bile acids on hepatic stellate cell activation2015
- Author(s)
  Yuga Teranishi, Tsutomu Matsubara, Naoshi Odagiri, Kazuo Ikeda, Norifumi Kawada
- Organizer
  ISCHS 2015
- Place of Presentation
  Asilomer, CA, USA
- Year and Date
  2015-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870501
[Presentation] 抗線維化in vitro評価系の構築と抗線維化物質の探索2015
- Author(s)
  松原勤、大黒敦子、松原三佐子、池田一雄、河田則文
- Organizer
  第41回日本肝臓学会西部会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26870501
[Presentation] Characterization of senescence-associated hepatic stellate cells using human primary culture cells2015
- Author(s)
  Naoshi Odagiri, Tsutomu Matsubara, Norifumi Kawada, Kazuo Ikeda
- Organizer
  ISCHS 2015
- Place of Presentation
  Asilomer, CA, USA
- Year and Date
  2015-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870501
[Presentation] アセトアミノフェン誘発肝障害における小胞体ストレス応答の役割
- Author(s)
  北村賢治、松原　勤、寺西優雅、仲谷和記、河田則文、池田一雄
- Organizer
  第28回肝類洞壁細胞研究会学術集会
- Place of Presentation
  アークホテル岡山（岡山県、岡山市）
- Year and Date
  2014-12-13 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-26870501

1. SATO-MATSUBARA Misako (00635120)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. Ikeda Kazuo (80275247)

# of Collaborated Projects: 4 results

# of Collaborated Products: 25 results
3. 湯川博 (30634646)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 川村悦史 (60419710)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 河田則文 (30271191)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
6. 藤井英樹 (20382070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. LE THITHANHTHUY (10572175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 鳴瀧彩絵 (10508203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 湯浅明子 (90295709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 藤原正澄 (30540190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 中台枝里子 (40453790)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 鹿野豊 (80634691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 中瀬生彦 (40432322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 吉成浩一 (60343399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 村上善基 (00397556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. 宇留島隼人 (90755745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. TERANISHI Yuga

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
18. ODAGIRI Naoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
19. ASAHINA Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. SAWAI Hiromi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. ENOMOTO Masaru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. KONDO Yasuteru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. SAWAI Hitomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 松原三佐子(佐藤三佐子)

# of Collaborated Projects: 0 results

# of Collaborated Products: 46 results
25. LE Thuy

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. 本多政夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 坂本直哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 中川美奈

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 日浅陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 田守昭博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 末次淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 吉里勝利

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 徳永文稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
34. 及川大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
35. 川田学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 西村勇姿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsubara Tsutomu 松原 勤

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HSD17B4の新機能に着目した肝硬変治療薬の開発Principal Investigator

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機能性ブロックポリペプチドを用いた臓器被膜の再構築Principal Investigator

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Functional analysis of hepatic stellate cell-expressed FXR in liver cirrhosis and carcinogenesisPrincipal Investigator

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Multiple comparative analysis of FXR-inhibitory effect on liver carcinogenesisPrincipal Investigator

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[Journal Article] Capacity of extracellular globins to reduce liver fibrosis via scavenging reactive oxygen species and promoting MMP-1 secretion2022

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[Journal Article] Hexa Histidine-Tagged Recombinant Human Cytoglobin Deactivates Hepatic Stellate Cells and Inhibits Liver Fibrosis by Scavenging Reactive Oxygen Species2021

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Matsubara Tsutomu 松原勤