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KAWADA Norifumi  河田 則文

ORCIDConnect your ORCID iD *help
… Alternative Names

KAWADA Norihumi  河田 則文

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Researcher Number 30271191
Other IDs
External Links
Affiliation (Current) 2022: 大阪公立大学, 大学院医学研究科, 教授
Affiliation (based on the past Project Information) *help 2022: 大阪市立大学, 医学(系)研究科(研究院), 教授
2015 – 2021: 大阪市立大学, 大学院医学研究科, 教授
2011 – 2014: 大阪市立大学, 医学(系)研究科(研究院), 教授
2013: 大阪市立大学, 医学研究院, 教授
2009 – 2011: Osaka City University, 大学院・医学研究科, 教授 … More
2007: Osaka City University, Graduate school of Medine, Faculty of Medicine, Professor
2006: Oosaka City University Medical School, Graduate School of Medicine, Associate Professor, 大学院医学研究科, 助教授
2006: 大阪市立大学, 大学院医学研究科, 教授
2005: 大阪市立大学, 医学研究科, 助教授
2005: Osaka City University, School of Nfedicine, Associate Professor, 医学部, 助教授
2005: Osaka City University, Department of Hepatology, Graduate School of Medicine, Associate Professor, 大学院・医学研究科, 助教授
2002 – 2004: Osaka City University, Medicine, Lecturer, 医学研究科, 講師
2002 – 2004: 大阪市立大学, 大学院・医学研究科, 講師
2001 – 2003: Osaka City University, Medicine, Lecturer, 医学部, 講師
1996 – 2001: 大阪市立大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Gastroenterology / Basic Section 53010:Gastroenterology-related / Carcinogenesis / Biological Sciences
Except Principal Investigator
General surgery / Gastroenterology / Digestive surgery / Basic Section 53010:Gastroenterology-related / Digestive surgery … More / General surgery / General anatomy (including Histology/Embryology) / General anatomy (including Histology/Embryology) / Embryonic/Neonatal medicine / Epidemiology and preventive medicine / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 59040:Nutrition science and health science-related Less
Keywords
Principal Investigator
サイトグロビン / 星細胞 / 肝線維化 / 肝硬変 / 線維芽細胞 / 肝癌 / 動物モデル / 肝星細胞 / liver fibrosis / 線維化 … More / ビタミンA / 肝がん / ヘモグロビン / ビタミンA貯蔵細胞 / 臓器線維化 / stellate cell / globin / コラーゲン / 筋線維芽細胞 / 平滑筋型アクチン / 一酸化窒素 / サイトカイン / 増殖因子 / 細胞外マトリックス / 肝障害 / ユラ-ゲン / 転写因子 / 脂肪肝 / 脂肪性肝炎 / 赤血球 / マクロファージ / ジェチルニトロサミン / サイトグロイン / ジエチルニトロサミン / 乳癌 / 自然発症 / 間質細胞 / プリオン蛋白 / サブトラクション / hepatic stellate cels / prion protein / STAP / グロビン / ヘム蛋白 / stap / heme protein / 炎症性腸疾患 / HLA-DR / 抗ペプチド / heme / oxygen / myofibroblast / vitamin A / α平滑筋アクチン / 炎症 / 発がん / プロモーター / 肝臓学 / Cytoglobin / TGFβ / ヒドロキシラジカル … More
Except Principal Investigator
肝線維化 / 星細胞 / ROCK / 肝星細胞 / 肝不全 / NAC / 肝障害 / 肝微小循環 / 生体顕微鏡 / Rho kinase阻害剤 / 虚血再潅流障害 / hepatic microcirculation / Rho kinase inhibitor / 肝細胞 / 細胞外マトリックス / チオレドキシン / コラーゲン / マイクロRNA / Liver failure / Liver fibrosis / hepatic stellate cell / 抗酸化剤 / PDGFレセプター / カテプシン / 肝硬変 / 供培養 / 酸化ストレス / 術後肝障害 / 肝再生 / B型肝炎 / 細胞培養 / Hepatic Stellate Cell / 類洞 / エンドトキシン / Intravital microscopyu / Y-27632 / enndotoxin / ROCK阻害剤 / N-アセチルシステイン / 肝繊維化 / thioredoxin / ischemia / reperfusion injury / intravital microscopy / N-acetylcisteine / liver failure / DDR2 / Src / Shc / MMP-2 / collagen / liver fibrosis / Cre / loxP / synemin / vimentin / 胆管癌 / 印刷所労働者 / 遺伝子 / N-acetyl-cysteine / 増殖因子 / 細胞増殖 / DNA合成 / 細胞間相互作用 / トランスジェニックマウス / 低分子RNA / Cre-loP / C型慢性肝炎 / インターフェロン / リバビリン / 脂肪性肝炎 / 細胞死 / cytokeratin 18 fragment / 脂肪肝の脆弱性 / 組織修復 / B型慢性肝炎 / マクロファージ / 肝脂肪化 / MSR-A / MSr-A / 脂肪肝炎 / IV型コラーゲン / 共培養 / Liver Failure / liver Regeneration / Hepatocyte / Hepatic Extracellular Matrix / Type IV Collagen / Cell Culture / Liver Fibrosis / Anti-oxidant / PDGF receptor / Catepsin / Liver cirrhosis / 類洞壁細胞 / 肝切除 / 急性肝不全 / 肝腺維化 / stellate cells / 肝癌 / 急性期肝障害 / 慢性肝炎 / 肝細胞癌 / chemoprevention / Hepatic stellate cells / アデノウイルスベクター / 臓器線維症 / TGF-beta / BMP-7 / Id2 / Id3 / Stellate cells / adenoviral vector / サイトグロビン / ヘムタンパク質 / トランスジェニックガエル / 無脳症 / 神経管閉鎖不全 / 分子発生学 / 体外受精 / 頭部形成遺伝子 / cytoglobin / heme-protein / transgenic forg / anencephaly / neural tube disclosure / molecular embryogenesis / in vitro fertilization / head organizer genes / 中間系フィラメント / Intermediate filament / liver fibrois / hepatic stellate cells / hepatocellular carcinoma / 有機溶剤 / 癌抑制遺伝子 / mRNA / microRNA / SKI / p21 / 若年 / 遺伝子発現 / 印刷所 / 胆管細胞癌 / 若年胆管細胞癌 / 印刷会社 / 代謝酵素 / 遺伝子発現異常 / micro RNA / C型肝炎 / SVR / 線維化 / バイオマーカー / 内科 / 肝炎 / HCC SNP / 大阪市 / 癌遺伝子 / 創薬 / 非アルコール性脂肪肝炎 / DIF-1 / Cytoglobin / Promoter / Demethylation / liver tumor / pancreatic tumor / 免疫チェックポイント分子 Less
  • Research Projects

    (38 results)
  • Research Products

    (203 results)
  • Co-Researchers

    (59 People)
  •  肝細胞のがん化における細胞間相互作用を介した星細胞の役割Principal Investigator

    • Principal Investigator
      河田 則文
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      大阪市立大学
  •  Cytoglobin (CYGB)-overexpression and targeted demethylation of CYGB promoter impair liver and pancreatic tumor growth

    • Principal Investigator
      HOANG HAI
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Osaka City University
  •  B型肝炎の治療抵抗性および病態進展における免疫チェックポイント分子の関与

    • Principal Investigator
      榎本 大
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Osaka City University
  •  Basic study for developing NASH therapeutic drugs by using a small molecule derived from the cellular slime mold serving as a lead compound

    • Principal Investigator
      石川 智久
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      University of Shizuoka
  •  地元大阪の印刷所労働者胆管がん組織を使ったがん遺伝子の探索:創薬基盤の構築

    • Principal Investigator
      川村 悦史
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Osaka City University
  •  活性化星細胞はサイトグロビンを介して肝細胞のがん化に直接的に関与するか?Principal Investigator

    • Principal Investigator
      河田 則文
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Osaka City University
  •  Development of anti-fibrotic therapy for liver disease by establishing technologies that regulate cytoglobin expression in hepatic stellate cellsPrincipal Investigator

    • Principal Investigator
      KAWADA NORIFUMI
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University
  •  MicroRNA as a biomarker for prediction of HCC development after achieving an SVR

    • Principal Investigator
      Enomoto Masaru
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University
  •  Genetic risk verification of juvenile-onset cholangiocarcinoma

    • Principal Investigator
      Kawamura Etsushi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Epidemiology and preventive medicine
    • Research Institution
      Osaka City University
  •  Study on miRNA expression and single nucleotide polymorphisms in hepatocellular carcinoma after HCV eradication

    • Principal Investigator
      HOANG HAI
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University
  •  Involvement of Cytoglobin expressed in hepatic stellate cells in the development of cancer derived from inflamed liver.Principal Investigator

    • Principal Investigator
      KAWADA NORIFUMI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University
  •  MicroRNA as a liver fibrosis marker in chronic hepatitis B

    • Principal Investigator
      Enomoto Masaru
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University
  •  Mechanism of formation of hepatic steatosis in Non-alcoholic fatty liver disease (NAFLD)

    • Principal Investigator
      Hideki Fujii
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University
  •  癌微小環境形成におけるサイトグロビン陽性あるいは陰性筋線維芽細胞の役割Principal Investigator

    • Principal Investigator
      河田 則文
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka City University
  •  The ability of tisuue repair and regeneration in steatohepatitic liver

    • Principal Investigator
      KAMOHARA Yukio
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  Involvement of cytoglobin-expressing mesenchymal cells in cancer developmentPrincipal Investigator

    • Principal Investigator
      KAWADA Norifumi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Carcinogenesis
    • Research Institution
      Osaka City University
  •  Analyses of the development of liver cancer and cirrhosis by using cytoglobin-deficient micePrincipal Investigator

    • Principal Investigator
      KAWADA Norifumi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University
  •  Intrahepatic microRNA expression and response to peginterferon-α and ribavirin therapy in patients with chronic hepatitis C

    • Principal Investigator
      ENOMOTO Masaru
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University
  •  変性赤血球による非アルコール性脂肪性肝炎病態の修飾Principal Investigator

    • Principal Investigator
      河田 則文
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University
  •  ShRNAライブラリーを用いた肝線維化,癌化関連因子の網羅的解析と治療への応用

    • Principal Investigator
      IKEDA Kazuo
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka City University
  •  The role of intermediateted filament proteins in hepatic stellate cells in the development of liver fibrosis and hepatocellular carcinoma

    • Principal Investigator
      UYAMA Naoki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Hyogo College of Medicine
  •  Molecular Mechanism for Anencephaly

    • Principal Investigator
      OBARA Masanobu
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Improvement of perioperative and postoperative management after hepatic resection for HCC by the regulation of hepatic stellate cells.

    • Principal Investigator
      HATANO Etsuro, 嶌原 康行
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyoto University
  •  Targeted and regulable expression of transgenes in hepatic stellate cells using an adenoviral Cre-loxP system

    • Principal Investigator
      IKEDA Kazuo
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Osaka City University
  •  Functional analysis of cytoglobin that is expressed and induced in liver cirrhosisPrincipal Investigator

    • Principal Investigator
      KAWADA Norifumi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University
  •  ストレス応答蛋白チオレドキシンによる新しい術後肝障害防止対策

    • Principal Investigator
      嶌原 康行
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Kyoto University
  •  Development of perioperative management for hepatic resection based on the stellate cell function

    • Principal Investigator
      SHIMAHARA Yasuyuki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kyoto University
  •  The signal pthway and the role of the discoidin domain receptor 2 (DDR2) which is stimulated by type I collagen

    • Principal Investigator
      IKEDA Kazuo
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Osaka City University
  •  Functional analysis of stap, a novel gene expressed in hepatic stellate cells and fibrotic liver tissue and its significance in clinicopathophysiologyPrincipal Investigator

    • Principal Investigator
      KAWADA Norifumi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University
  •  肝細胞・肝星細胞の供培養による細胞増殖相互作用

    • Principal Investigator
      嶌原 康行
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Kyoto University
  •  Regulation of hepatic micro circulation by hepatic stellate cell-Application of NAC to liver failure

    • Principal Investigator
      SHIMAHARA Yasuyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      KYOTO UNIVERSITY
  •  N-acetylcysteineによる星細胞活性化の制御

    • Principal Investigator
      SHIMAHARA Yasuyuki
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyoto University
  •  Strategy for Liver Failure by Regulating Hepatic Microcirculation through Hepatic Stellate Cell Activatity

    • Principal Investigator
      SHIMAHARA Yasuyuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      KYOTO UNIVERSITY
  •  Aspect of Strategy for Liver Failure by Regelating Hepatic Stellate Cell Activation

    • Principal Investigator
      SHIMAHARA Yasuyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      KYOTO UNIVERSITY
  •  Pathophysiological Analysis of Prion Protein Expression in the LiverPrincipal Investigator

    • Principal Investigator
      KAWADA Norifumi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University
  •  New Strategy for Liver Failure by Regulating Hepatic Extracellular Matrix

    • Principal Investigator
      SHIMAHARA Yasuyuki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      KYOTO UNIVERSITY
  •  肝星細胞活性化の分子解析とそれを利用した肝線維化抑制法の開発Principal Investigator

    • Principal Investigator
      河田 則文
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University
  •  肝類洞細胞に発現する特異蛋白のcDNAクローニングとその機能解析Principal Investigator

    • Principal Investigator
      河田 則文
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka City University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2007 2006 2005 2003 2002 2001 Other

All Journal Article Presentation Book Patent

  • [Book] Liver Pathophysiology: Therapies and Antioxidants2017

    • Author(s)
      Le Thi Thanh Thuy, Tuong Thi Van Thuy, Hoang Hai, and Norifumi Kawada
    • Total Pages
      914
    • Publisher
      Elsevier
    • Data Source
      KAKENHI-PROJECT-26860522
  • [Book] 肝臓の線維化研究の進展2010

    • Author(s)
      河田則文
    • Total Pages
      7
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-22650224
  • [Book] 肝臓の線維化研究の進展2010

    • Author(s)
      河田則文
    • Total Pages
      7
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-21390232
  • [Journal Article] 肝星細胞の活性化の仕組み サイトグロビンの作用から見えてくる新しい視点2019

    • Author(s)
      松原 三佐子, 河田 則文, 吉里 勝利
    • Journal Title

      細胞

      Volume: 51 Pages: 530-534

    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Journal Article] Obesity and hiatal hernia may be non-allergic risk factors for esophageal eosinophilia in Japanese adults.2019

    • Author(s)
      Tanaka F, Fukumoto S, Morisaki T, Otani K, Hosomi S, Nagami Y, Kamata N, Taira K, Nakano A, Kimura T, Yamagami H, Tanigawa T, Morikawa H, Watanabe T, Kawada N, Hirata K, Fujiwara Y.
    • Journal Title

      Esophagus

      Volume: 16 Pages: 309-315

    • DOI

      10.1007/s10388-019-00662-3

    • NAID

      120006876362

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07917, KAKENHI-PROJECT-19H03641
  • [Journal Article] 肝機能障害を契機に診断されたサルコイドーシス5例の検討2019

    • Author(s)
      焦 光裕、榎本 大、小谷 晃平、小田 桐直志、吉田 香奈子、元山 宏行、小塚 立蔵、藤井 英樹、萩原 淳司、打田 佐和子、森川 浩安、村上 善基、田守 昭博、河田 則文
    • Journal Title

      肝臓

      Volume: 60 Pages: 405-413

    • NAID

      130007741895

    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Journal Article] HOMA-IR: An independent predictor of advanced liver fibrosis in nondiabetic non-alcoholic fatty liver disease2019

    • Author(s)
      Fujii H, Yoneda M, et al.
    • Journal Title

      J Gastroenterol Hepatol. 2019 Aug;34(8):1390-1395.

      Volume: in press Pages: 1390-1395

    • DOI

      10.1111/jgh.14595

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07637, KAKENHI-PROJECT-17K15866, KAKENHI-PROJECT-17K09437, KAKENHI-PROJECT-19H03641, KAKENHI-PROJECT-17H06269, KAKENHI-PROJECT-17K09434
  • [Journal Article] Hepatitis C virus recurrence in two patients who achieved sustained viral response with interferon-free direct-acting antiviral therapy: reinfection or relapse?2019

    • Author(s)
      Yukawa Y, Tamori A, Iio E, Ogawa S, Yoshida K, Uchida-Kobayashi S, Enomoto M, Tanaka Y, Kawada N.
    • Journal Title

      Clin J Gastroenterol

      Volume: 12 Pages: 598-602

    • DOI

      10.1007/s12328-019-01001-w

    • NAID

      120006866793

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Journal Article] C型肝炎 HCV排除は肝がんを抑制するのか 外来でのフォローはどうするか2019

    • Author(s)
      榎本 大(大阪市立大学 大学院医学研究科肝胆膵病態内科学), 伊倉 義弘, 田守 昭博, 河田 則文
    • Journal Title

      内科

      Volume: 123 Pages: 1081-1085

    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Journal Article] Interstitial pneumonia suspected during regorafenib administration and exacerbated by subsequent therapy with lenvatinib for unresectable hepatocellular carcinoma.2019

    • Author(s)
      Kotani K, Enomoto M, Okada M, Yoshida K, Motoyama H, Fiji H, Hagihara A, Uchida-Kobayashi S, Mordkawa H, Murakami Y, Tamori A, Kanada N.
    • Journal Title

      Clin J Gastroenterol

      Volume: - Pages: 355-360

    • DOI

      10.1007/s12328-019-00983-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16472, KAKENHI-PROJECT-17K09467, KAKENHI-PROJECT-19H03641
  • [Journal Article] Intention-to-treat assessment of glecaprevir + pibrentasvir combination therapy for patients with chronic hepatitis C in the real world.2019

    • Author(s)
      Tamori A, Inoue K, Kagawa T, Takaguchi K, Nouso K, Iwasaki Y, Minami M, Hai H, Enomoto M, Kawada N.
    • Journal Title

      Hepatol Res

      Volume: 49 Pages: 1365-1373

    • DOI

      10.1111/hepr.13410

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Journal Article] Association between Functional Dyspepsia and Gastric Depressive Erosions in Japanese Subjects.2019

    • Author(s)
      Tanaka F, Tominaga K, Fujikawa Y, Morisaki T, Otani K, Hosomi S, Nagami Y, Kamata N, Taira K, Nakano A, Kimura T, Yamagami H, Tanigawa T, Morikawa H, Fukumoto S, Watanabe T, Kawada N, Hirata K, Fujiwara Y.
    • Journal Title

      Intern Med

      Volume: 58 Pages: 321-328

    • NAID

      130007588506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Journal Article] Last crusade against HCV: Direct-acting antiviral treatment for marginalized populations.2019

    • Author(s)
      Fujii H, Enomoto M, Murakami Y, Hagihara A, Kawada N, Saito S.
    • Journal Title

      J Viral Hepat

      Volume: 26 Pages: 1501-1501

    • DOI

      10.1111/jvh.13190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Journal Article] Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells.2019

    • Author(s)
      Odagiri Naoshi、Matsubara Tsutomu、Higuchi Moe, Takada Sayuri, Urushima Hayato, Sato-Matsubara Misako, Teranishi Yuga, Yoshizato Katsutoshi, Kawada Norifumi, Ikeda Kazuo.
    • Journal Title

      Molecular and Cellular Biochemistry

      Volume: 455(1-2) Pages: 7-19

    • DOI

      10.1007/s11010-018-3466-x

    • NAID

      120006847891

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18012, KAKENHI-PROJECT-16H05290, KAKENHI-PROJECT-16K08472, KAKENHI-PROJECT-16K19362, KAKENHI-PROJECT-18K07952
  • [Journal Article] Role of the Gut-Liver Axis in Liver Inflammation, Fibrosis, and Cancer: A Special Focus on the Gut Microbiota Relationship.2019

    • Author(s)
      Ohtani N, Kawada N.
    • Journal Title

      Hepatol Commun

      Volume: 3 Pages: 456-470

    • DOI

      10.1002/hep4.1331

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Journal Article] Switching to tenofovir disoproxil fumarate vs continuing treatment in patients with chronic hepatitis B who maintain long-term virological response to entecavir therapy: A randomized trial.2019

    • Author(s)
      Iida-Ueno A, Enomoto M, Kozuka R, Tamori A, Kawada N.
    • Journal Title

      J Med Virol

      Volume: 91 Pages: 1295-1300

    • DOI

      10.1002/jmv.25442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Journal Article] The presence of multiple NS 5A RAS s is associated with the outcome of sofosbuvir and ledipasvir therapy in NS 5A inhibitor‐na?ve patients with chronic HCV genotype 1b infection in a real‐world cohort2018

    • Author(s)
      Kozuka R, Hai H, Motoyama H, Hagihara A, Fujii H, Uchida-Kobayashi S, Mordkawa H, Enomoto M, Murakami Y, Kanada N, Tamori A
    • Journal Title

      Journal of Viral Hepatitis

      Volume: - Pages: 535-542

    • DOI

      10.1111/jvh.12850

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09019, KAKENHI-PROJECT-17K09467, KAKENHI-PROJECT-16K09369
  • [Journal Article] Stagnation of histopathological improvement is a predictor of hepatocellular carcinoma development after hepatitis C Virus eradication2018

    • Author(s)
      Motoyama H, Tamori A, Kubo S, Uchida-Kobayashi S, Takemura S, Tanaka S, Ohfuji S, Teranishi Y, Kozuka R, Kawamura E, Hagihara A, Morikawa H, Enomoto M, Murakami Y, Kawada N.
    • Journal Title

      PLOS ONE

      Volume: 13 Pages: 0194163-0194163

    • DOI

      10.1371/journal.pone.0194163

    • NAID

      120006411697

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04124, KAKENHI-PROJECT-15K09019, KAKENHI-PROJECT-15K10194, KAKENHI-PROJECT-17K09467, KAKENHI-PROJECT-18K08654, KAKENHI-PROJECT-16H05290, KAKENHI-PROJECT-16K09369
  • [Journal Article] Successful direct-acting antiviral treatment of three patients with genotype 2/1 recombinant hepatitis C virus2018

    • Author(s)
      Okada Masako、Hai Hoang、Tamori Akihiro、Uchida-Kobayashi Sawako、Enomoto Masaru、Kumada Hiromitsu、Kawada Norifumi
    • Journal Title

      Clinical Journal of Gastroenterology

      Volume: 印刷中

    • DOI

      10.1007/s12328-018-0922-9

    • NAID

      120006866794

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Journal Article] Short-term histological evaluations after achieving a sustained virological response to direct-acting antiviral treatment for chronic hepatitis C2018

    • Author(s)
      Enomoto Masaru、Ikura Yoshihiro、Tamori Akihiro、Kozuka Ritsuzo、Motoyama Hiroyuki、Kawamura Etsushi、Hagihara Atsushi、Fujii Hideki、Uchida-Kobayashi Sawako、Morikawa Hiroyasu、Murakami Yoshiki、Kawada Norifumi
    • Journal Title

      United European Gastroenterol J

      Volume: 6 Pages: 1391-1400

    • DOI

      10.1177/2050640618791053

    • NAID

      120006533846

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09467, KAKENHI-PROJECT-15K08649, KAKENHI-PROJECT-16K09369
  • [Journal Article] Selective overexpression of cytoglobin in stellate cells attenuates thioacetamide-induced liver fibrosis in mice2018

    • Author(s)
      Thi Thanh Hai N, Thuy LTT, Shiota A, Kadono C, Daikoku A, Hoang DV, Dat NQ, Sato-Matsubara M, Yoshizato K, Kawada N.
    • Journal Title

      Scientific Reports

      Volume: 8 Pages: 17860-17860

    • DOI

      10.1038/s41598-018-36215-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05290, KAKENHI-PROJECT-16K19363
  • [Journal Article] Remission of Psoriasis After Treatment of Chronic Hepatitis C Virus Infection With Direct-Acting Antivirals2018

    • Author(s)
      Enomoto Masaru、Tateishi Chiharu、Tsuruta Daisuke、Tamori Akihiro、Kawada Norifumi
    • Journal Title

      Annals of Internal Medicine

      Volume: 168 Pages: 678-678

    • DOI

      10.7326/l17-0613

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Journal Article] Low incidence of hepatitis B virus reactivation and subsequent hepatitis in patients with chronic hepatitis C receiving direct-acting antiviral therapy.2018

    • Author(s)
      Tamori A.、Abiru S.、Enomoto H.、Kioka K.、Korenaga M.、Tani J.、Enomoto M.、Sugiyama M.、Masaki T.、Kawada N.、Yatsuhashi H.、Nishiguchi S.、Mizokami M.
    • Journal Title

      J Viral Hepat. 2

      Volume: - Pages: 608-611

    • DOI

      10.1111/jvh.12840

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09369, KAKENHI-PROJECT-16K09388
  • [Journal Article] Correlation between polymorphism in the inosine triphosphatase and the reductions in hemoglobin concentration and ribavirin dose during sofosbuvir and ribavirin therapy.2017

    • Author(s)
      Kozuka R, Hai H, Teranishi Y, Motoyama H, Kawamura E, Hagihara A, Uchida-Kobayashi S, Morikawa H, Enomoto M, Murakami Y, Kawada N, Tamori A.
    • Journal Title

      JGastroenterol Hepatol.

      Volume: 32 Pages: 1495-1502

    • NAID

      120006510936

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Journal Article] Detection of HCV RNA in Sustained Virologic Response to?Direct-Acting Antiviral Agents: Occult or Science Fiction?2017

    • Author(s)
      Enomoto Masaru、Murakami Yoshiki、Kawada Norifumi
    • Journal Title

      Gastroenterology

      Volume: 153 Pages: 327-328

    • DOI

      10.1053/j.gastro.2017.03.075

    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Journal Article] Long-Term Follow-Up of Resistance-Associated Substitutions in Hepatitis C Virus in Patients in Which Direct Acting Antiviral-Based Therapy Failed2017

    • Author(s)
      Yoshida Kanako、Hai Hoang、Tamori Akihiro、Teranishi Yuga、Kozuka Ritsuzo、Motoyama Hiroyuki、Kawamura Etsushi、Hagihara Atsushi、Uchida-Kobayashi Sawako、Morikawa Hiroyasu、Enomoto Masaru、Murakami Yoshiki、Kawada Norifumi
    • Journal Title

      Int J Mol Sci.

      Volume: 18 Pages: 962-962

    • DOI

      10.3390/ijms18050962

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09369, KAKENHI-PROJECT-17K09467, KAKENHI-PROJECT-15K09019
  • [Journal Article] "Long-Term Follow-Up of Resistance-Associated Substitutions in Hepatitis C Virus in Patients in Which Direct Acting Antiviral-Based Therapy Failed.2017

    • Author(s)
      Yoshida K, Hai H, Tamori A, Teranishi Y, Kozuka R, Motoyama H, Kawamura E, Hagihara A, Uchida-Kobayashi S, Morikawa H, Enomoto M, Murakami Y, Kawada N.
    • Journal Title

      Int J Mol Sci.

      Volume: 18

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Journal Article] Interstitial fluid flow-induced growth potential and hyaluronan synthesis of fibroblasts in a fibroblast-populated stretched collagen gel culture.2017

    • Author(s)
      Saito N, Adachi H, Tanaka H, Nakata S, Kawada N, Oofusa K, Yoshizato K.
    • Journal Title

      Biochim Biophys Acta.

      Volume: 1861 Pages: 2261-2273

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Journal Article] Possible Involvement of Nitric Oxide in Enhanced Liver Injury and Fibrogenesis during Cholestasis in Cytoglobin-deficient Mice.2017

    • Author(s)
      Van Thuy TT, Thuy LT, Yoshizato K, Kawada N.
    • Journal Title

      Sci Rep.

      Volume: 3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Journal Article] Polymorphisms in MICA, but not in DEPDC5, HCP5 or PNPLA3, are associated with chronic hepatitis C-related hepatocellular carcinoma.2017

    • Author(s)
      Hai Hoang、Tamori Akihiro、Thuy Le Thi Thanh、Yoshida Kanako、Hagihara Atsushi、Kawamura Etsushi、Uchida-Kobayashi Sawako、Morikawa Hiroyasu、Enomoto Masaru、Murakami Yoshiki、Kawada Norifumi
    • Journal Title

      Sci Rep.

      Volume: 7 Pages: 11912-11912

    • DOI

      10.1038/s41598-017-10363-5

    • NAID

      120006346630

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09369, KAKENHI-PROJECT-17K09467, KAKENHI-PROJECT-16K19363, KAKENHI-PROJECT-15K09019
  • [Journal Article] ITPA polymorphism correlates with the reductions in hemoglobin concentration and ribavirin dose during sofosbuvir and ribavirin therapy.2017

    • Author(s)
      Tamori A, Yoshida K, Kurai O, Kioka K, Hai H, Kozuka R, Motoyama H, Kawamura E, Hagihara A, Uchida-Kobayashi S, Morikawa H, Enomoto M, Murakami Y, Kawada N
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 46 Pages: 1311-1320

    • DOI

      10.1111/jgh.13743

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860522, KAKENHI-PROJECT-15K09019, KAKENHI-PROJECT-16K09369, KAKENHI-PROJECT-17K09467
  • [Journal Article] Detection of HCV RNA in Sustained Virologic Response to Direct-Acting Antiviral Agents: Occult or Science Fiction?2017

    • Author(s)
      Enomoto M, Murakami Y, Kawada N.
    • Journal Title

      Gastroenterology

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Journal Article] The impact of hepatitis C virus outside the liver: Evidence from Asia.2017

    • Author(s)
      Younossi ZM, Tanaka A, Eguchi Y, Lim YS, Yu ML, Kawada N, Dan YY, Brooks-Rooney C, Negro F, Mondelli MU.
    • Journal Title

      Liver Int.

      Volume: 37 Pages: 159-172

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Journal Article] Outcomes for Cirrhotic Patients with Hepatitis C Virus 1b Treated with Asunaprevir and Daclatasvir Combination2017

    • Author(s)
      Tamori Akihiro、Hai Hoang、Uchida-Kobayashi Sawako、Enomoto Masaru、Kozuka Ritsuzo、Motoyama Hiroyuki、Kawamura Etsushi、Hagihara Atsushi、Teranishi Yuga、Yoshida Kanako、Morikawa Hiroyasu、Murakami Yoshiki、Kawada Norifumi
    • Journal Title

      Ann Hepatol.

      Volume: 16 Pages: 734-741

    • DOI

      10.5604/01.3001.0010.2732

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09369, KAKENHI-PROJECT-17K09467, KAKENHI-PROJECT-15K09019
  • [Journal Article] 3.Absence of cytoglobin promotes multiple organ abnormalities in aged mice2016

    • Author(s)
      Thuy le TT
    • Journal Title

      Scientific Reports

      Volume: - Pages: 1-15

    • DOI

      10.1038/srep24990

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05290, KAKENHI-PROJECT-26860522, KAKENHI-PROJECT-16K19363
  • [Journal Article] Pathophysiological role of cytoglobin, the fourth globin in mammals, in liver diseases.2016

    • Author(s)
      Thuy Le TT, Nguen Thi Thanh Hai, Hoang Hai, Norifumi Kawada.
    • Journal Title

      Histol Histopathol.

      Volume: 31 Pages: 257-267

    • Data Source
      KAKENHI-PROJECT-26860522
  • [Journal Article] Putting "sticky notes" on the electronic medical record to promote intra-hospital referral of hepatitis B and C virus-positive patients to hepatology specialists: an exploratory study.2016

    • Author(s)
      Fujii H, Yamaguchi S, Kurai O, Miyano M, Ueda W, Oba H, Aoki T, Enomoto M, Kawada N, Okawa K.
    • Journal Title

      BMC Infect Dis.

      Volume: 16 Pages: 410-410

    • DOI

      10.1186/s12879-016-1765-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Journal Article] Randomized trial of combined triple therapy comprising two types of peginterferon with simeprevir in patients with hepatitis C virus genotype 1b.2016

    • Author(s)
      Tamori A, Yoshida K, Kurai O, Kioka K, Hai H, Kozuka R, Motoyama H, Kawamura E, Hagihara A, Uchida-Kobayashi S, Morikawa H, Enomoto M, Murakami Y, Kawara N.
    • Journal Title

      Hepatol Res.

      Volume: 46 Pages: 1311-1320

    • DOI

      10.1111/hepr.12689

    • NAID

      120006534926

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09019, KAKENHI-PROJECT-16K09369
  • [Journal Article] Pathophysiological role of cytoglobin, the fourth globin in mammals, in liver diseases.2016

    • Author(s)
      Thuy Le TT, Hai NT, Hai H, Kawada N.
    • Journal Title

      Histol Histopathol.

      Volume: 31 Pages: 257-267

    • Data Source
      KAKENHI-PROJECT-25293177
  • [Journal Article] Recent Advances in Antiviral Therapy for Chronic Hepatitis C.2016

    • Author(s)
      Tamori A, Enomoto M, Kawada N.
    • Journal Title

      Mediators Inflamm.

      Volume: 2016 Pages: 1-11

    • DOI

      10.1155/2016/6841628

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09019, KAKENHI-PROJECT-16K09369
  • [Journal Article] Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism2015

    • Author(s)
      Yuga Teranishi, Tsutomu Matsubara, Kristopher W Krausz, Thi T T Le, Frank J Gonzalez, Katsutoshi Yoshizato,Kazuo Ikeda and Norifumi Kawada
    • Journal Title

      Laboratory Investigation

      Volume: 00 Pages: 1-10

    • Data Source
      KAKENHI-PROJECT-25293177
  • [Journal Article] Cytoglobin as a Marker of Hepatic Stellate Cell-derived Myofibroblasts.2015

    • Author(s)
      Kawada N.
    • Journal Title

      Front Physiol.

      Volume: 6 Pages: 329-329

    • DOI

      10.3389/fphys.2015.00329

    • Data Source
      KAKENHI-PROJECT-25293177
  • [Journal Article] Cytoglobin deficiency promotes liver cancer development from hepatosteatosis through activation of the oxidative stress pathway.2015

    • Author(s)
      Thuy le TT, Matsumoto Y, Thuy TT, Hai H, Suoh M, Urahara Y, Motoyama H, Fujii H, Tamori A, Kubo S, Takemura S, Morita T, Yoshizato K, Kawada N
    • Journal Title

      Am J Pathol.

      Volume: 185 Pages: 1045-1060

    • DOI

      10.1016/j.ajpath.2014.12.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10194, KAKENHI-PROJECT-25293177
  • [Journal Article] Long-Term Outcome of Sequential Therapy with Lamivudine Followed by Interferon-β in Nucleoside-Naive, Hepatitis B e-Antigen-Positive Patients with Chronic Hepatitis B Virus Genotype C Infection2015

    • Author(s)
      Enomoto M, Nishiguchi S, Tamori A, Kozuka R, Hayashi T, Kohmoto MT, Jomura H, Morikawa H, Murakami Y, Shiomi S, Kawada N
    • Journal Title

      J Interferon Cytokine Res

      Volume: 35 Pages: 613-620

    • DOI

      10.1089/jir.2014.0234

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461006
  • [Journal Article] Effects on anemia of drug adjustment in patients with chronic hepatitis C during teleaprevir-combined therapy.2015

    • Author(s)
      Tamori A, Kioka K, Sakaguchi H, Enommoto M, Hai H, Kawamura E, Hagihara A, Fujii H, Uchida-Kobayashi S, Iwai S, Morikawa H, Murakami Y, Kawadaki Y, Tsuruta D, Kawada N.
    • Journal Title

      Ann Hepatol.

      Volume: 14 Pages: 28-35

    • Data Source
      KAKENHI-PROJECT-26860522
  • [Journal Article] Cytoglobin Deficiency Promotes Liver Cancer Development from Hepatosteatosis through Activation of the Oxidative Stress Pathway.2015

    • Author(s)
      Thuy Le TT, Matsumoto Y, Thuy TT, Hai H, Suoh M, Urahara Y, Motoyama H, Fujii,Tamori A, Kubo S, Takemura S, Morita T, Yoshizato K, Kawada N.
    • Journal Title

      Am J Pathol.

      Volume: 185 Pages: 1045-1060

    • Data Source
      KAKENHI-PROJECT-26860522
  • [Journal Article] Cytoglobin Deficiency Promotes Liver Cancer Development from Hepatosteatosis through Activation of the Oxidative Stress Pathway2015

    • Author(s)
      Thuy le TT, Matsumoto Y, Thuy TT, Hai H, Suoh M, Urahara Y, Motoyama H, Fujii H, Tamori A, Kubo S, Takemura S, Morita T, Yoshizato K, Kawada N.
    • Journal Title

      Am J Pathol.

      Volume: 185 Pages: 1045-1060

    • Data Source
      KAKENHI-PROJECT-25293177
  • [Journal Article] Noninvasive assessment of liver fibrosis in patients with chronic hepatitis B2014

    • Author(s)
      Enomoto M, Morikawa H, Tamori A, Kawada N
    • Journal Title

      World J Gastroenterol

      Volume: 20 Pages: 12031-12038

    • DOI

      10.3748/wjg.v20.i34.12031

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461006
  • [Journal Article] Cytoglobin is expressed in hepatic stellate cells, but not in myofibroblasts, in normal and fibrotic human liver.2014

    • Author(s)
      Motoyama H, Komiya T, Thuy le TT, Tamori A, Enomoto M, Morikawa H, Iwai S,Uchida-Kobayashi S, Fujii H, Hagihara A, Kawamura E, Murakami Y, Yoshizato K,Kawada N.
    • Journal Title

      Lab Invest.

      Volume: 94 Pages: 192-207

    • Data Source
      KAKENHI-PROJECT-25293177
  • [Journal Article] Entecavir and interferon-α sequential therapy in Japanese patients with hepatitis B e antigen-positive chronic hepatitis B2013

    • Author(s)
      Enomoto M, Nishiguchi S, Tamori A, Kobayashi S, Sakaguchi H, Shiomi S, Kim SR, Enomoto H, Saito M, Imanishi H, Kawada N.
    • Journal Title

      Journal of Gastroenterology

      Volume: 48 Pages: 397-404

    • DOI

      10.1007/s00535-012-0645-5

    • NAID

      10031169214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590985, KAKENHI-PROJECT-25461006
  • [Journal Article] Combination therapy with a nucleos(t)ide analogue and interferon for chronic hepatitis B : simultaneous or sequential2013

    • Author(s)
      Enomoto M, Tamori A, Nishiguchi S, Kawada N.
    • Journal Title

      Journal of Gastroenterology

      Volume: 48 Pages: 999-1005

    • DOI

      10.1007/s00535-012-0742-5

    • NAID

      10031201970

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590985, KAKENHI-PROJECT-25461006
  • [Journal Article] Inflammation and fibrogenesis in steatohepatitis2012

    • Author(s)
      Fujii H, Kawada N.
    • Journal Title

      J Gastroenterol

      Volume: 47 Pages: 215-25

    • NAID

      10030559576

    • Data Source
      KAKENHI-PROJECT-22650224
  • [Journal Article] Antifibrotic role of macrophage migration inhibitory factor : discovery of an unexpected function. Thuy le TT2012

    • Author(s)
      Kawada N.
    • Journal Title

      Hepatology

      Volume: 55 Pages: 1295-7

    • Data Source
      KAKENHI-PROJECT-22650224
  • [Journal Article] N-Acetylglucosaminyltransferase V regulates TGF-βresponse in hepatic stellate cells and the progression of steatohepatitis2012

    • Author(s)
      Kamada Y, Mori K, Matsumoto H, Kiso S, Yoshida Y, Shinzaki S, Hiramatsu N, Ishii M, Moriwaki K, Kawada N, Takehara T, Miyoshi E.
    • Journal Title

      Glycobiology

      Volume: 22 Pages: 778-87

    • Data Source
      KAKENHI-PROJECT-22650224
  • [Journal Article] Fascin, a novel marker of human hepatic stellate cells, may regulate their proliferation, migration, and collagen gene expression through the FAK-PI3K-Akt pathway2012

    • Author(s)
      Uyama N, Iimuro Y, Kawada N, Reynaert H, Suzumura K, Hirano T, Kuroda N, Fujimoto J.
    • Journal Title

      Lab Invest

      Volume: 92 Pages: 57-71

    • Data Source
      KAKENHI-PROJECT-21390232
  • [Journal Article] Antifibrotic role of macrophage migration inhibitory factor : discovery of an unexpected function. Thuy le TT2012

    • Author(s)
      Kawada N.
    • Journal Title

      Hepatology

      Volume: 55 Pages: 1295-7

    • Data Source
      KAKENHI-PROJECT-21390232
  • [Journal Article] Inflammation and fibrogenesis in steatohepatitis2012

    • Author(s)
      Fujii H, Kawada N.
    • Journal Title

      J Gastroenterol

      Volume: 47 Pages: 215-25

    • NAID

      10030559576

    • Data Source
      KAKENHI-PROJECT-21390232
  • [Journal Article] MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis2012

    • Author(s)
      Ogawa T, Enomoto M, Fujii H, Sekiya Y, Yoshizato K, Ikeda K, Kawada N
    • Journal Title

      Gut

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-22650224
  • [Journal Article] N-Acetylglucosaminyltransferase V regulates TGF-βresponse in hepatic stellate cells and the progression of steatohepatitis2012

    • Author(s)
      Kamada Y, Mori K, Matsumoto H, Kiso S, Yoshida Y, Shinzaki S, Hiramatsu N, Ishii M, Moriwaki K, Kawada N, Takehara T, Miyoshi E.
    • Journal Title

      Glycobiology

      Volume: 22 Pages: 778-87

    • Data Source
      KAKENHI-PROJECT-21390232
  • [Journal Article] Response-guided therapy for patients with chronic hepatitis who have high viral loads of hepatitis C virus genotype 22012

    • Author(s)
      Yamaguchi Y, Tamori A, Tanaka Y, Iwai S, Kobayashi S, Fujii H, Morikawa H, Hagihara A, Enomoto M, Kawada N
    • Journal Title

      Hepatol Res

      Volume: (印刷中)

    • DOI

      10.1111/j.1872-034x.2011.00956.x

    • NAID

      10031144269

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Journal Article] Fascin, a novel marker of human hepatic stellate cells, may regulate their proliferation, migration, and collagen gene expression through the FAK-PI3K-Akt pathway2012

    • Author(s)
      Uyama N, Iimuro Y, Kawada N, Reynaert H, Suzumura K, Hirano T, Kuroda N, Fujimoto J.
    • Journal Title

      Lab Invest

      Volume: 92 Pages: 57-71

    • Data Source
      KAKENHI-PROJECT-22650224
  • [Journal Article] MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis.2012

    • Author(s)
      Ogawa T, Enomoto M, Fujii H, Sekiya Y, Yoshizato K, Ikeda K, Kawada N.
    • Journal Title

      Gut

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-21390232
  • [Journal Article] Mosapride Citrate on Gastric Emptying in Interferon-Induced Gastroparesis2012

    • Author(s)
      Kawamura E, Enomoto M, Kotani K, Hagihara A, Fujii H, Kobayashi S, Iwai S, Morikawa H, Kawabe J, Tominaga K, Tamori A, Shiomi S, Kawada N
    • Journal Title

      Dig Dis Sci

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Journal Article] MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis2012

    • Author(s)
      Ogawa T, Enomoto M, Fujii H, Sekiya Y, Yoshizato K, Ikeda K, Kawada N
    • Journal Title

      Gut

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Journal Article] Cytoglobin, a novel member of the globin family, protects kidney fibroblasts against oxidative stress under ischemic conditions2011

    • Author(s)
      Nishi H, Inagi R, Kawada N, Yoshizato K, Mimura I, Fujita T, Nangaku M.
    • Journal Title

      Am J Pathol

      Volume: 178 Pages: 128-39

    • Data Source
      KAKENHI-PROJECT-21390232
  • [Journal Article] Cytoglobin, a novel member of the globin family, protects kidney fibroblasts against oxidative stress under ischemic conditions2011

    • Author(s)
      Nishi H, Inagi R, Kawada N, Yoshizato K, Mimura I, Fujita T, Nangaku M.
    • Journal Title

      Am J Pathol

      Volume: 178 Pages: 128-39

    • Data Source
      KAKENHI-PROJECT-22650224
  • [Journal Article] Evolution of hepatic fibrosis research2011

    • Author(s)
      Kawada N.
    • Journal Title

      Hepatol Res

      Volume: 41 Pages: 199-208

    • Data Source
      KAKENHI-PROJECT-22650224
  • [Journal Article] Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-β-induced inhibition of hepatic stellate cell proliferation2011

    • Author(s)
      Sekiya Y, Ogawa T, Iizuka M, Yoshizato K, Ikeda K, Kawada N.
    • Journal Title

      J Cell Physiol

      Volume: 226 Pages: 2535-42

    • Data Source
      KAKENHI-PROJECT-22650224
  • [Journal Article] Favorable factors for re-treatment with pegylated interferon α2a plus ribavirin in patients with high viral loads of genotype 1 hepatitis C virus2011

    • Author(s)
      Tamori A, Kioka K, Kurai O, Sakaguchi H, Enomoto M, Fujii H, Kobayashi S, Iwai S, Morikawa H, Yamaguchi S, Kawasaki Y, Oka H, Tanaka Y, Kawada N
    • Journal Title

      Hepatol Res

      Volume: 41 Pages: 1169-77

    • NAID

      10031144195

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Journal Article] Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient mice. Thuy le TT2011

    • Author(s)
      Morita T, Yoshida K, Wakasa K, Iizuka M, Ogawa T, Mori M, Sekiya Y, Momen S, Motoyama H, Ikeda K, Yoshizato K, Kawada N.
    • Journal Title

      Am J Pathol

      Volume: 179 Pages: 1050-60

    • Data Source
      KAKENHI-PROJECT-21390232
  • [Journal Article] Cytoglobin expression of rectal subepithelial myofibroblasts : significant alterations of cytoglobin+stromal cells in long-standing ulcerative colitis2011

    • Author(s)
      Okayasu I, Mikami T, Yoshida T, Hana K, Yokozawa M, Sada M, Fujiwara M, Kawada N.
    • Journal Title

      Histol Histopathol

      Volume: 26 Pages: 679-88

    • Data Source
      KAKENHI-PROJECT-22650224
  • [Journal Article] Evolution of hepatic fibrosis research2011

    • Author(s)
      Kawada N.
    • Journal Title

      Hepatol Res

      Volume: 41 Pages: 199-208

    • Data Source
      KAKENHI-PROJECT-21390232
  • [Journal Article] Cytoglobin expression of rectal subepithelial myofibroblasts : significant alterations of cytoglobin+stromal cells in long-standing ulcerative colitis2011

    • Author(s)
      Okayasu I, Mikami T, Yoshida T, Hana K, Yokozawa M, Sada M, Fujiwara M, Kawada N.
    • Journal Title

      Histol Histopathol

      Volume: 26 Pages: 679-88

    • Data Source
      KAKENHI-PROJECT-21390232
  • [Journal Article] Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient mice. Thuy le TT2011

    • Author(s)
      Morita T, Yoshida K, Wakasa K, Iizuka M, Ogawa T, Mori M, Sekiya Y, Momen S, Motoyama H, Ikeda K, Yoshizato K, Kawada N.
    • Journal Title

      Am J Pathol

      Volume: 179 Pages: 1050-60

    • Data Source
      KAKENHI-PROJECT-22650224
  • [Journal Article] Could trastuzumab suppress hepatitis C virus in a patient with chronic hepatitis and breast cancer?2011

    • Author(s)
      Tamori A, Kawajiri H, Takashima T, Motoyama H, Morikawa H, Enomoto M, Hirakawa K, Kawada N
    • Journal Title

      Am J Gastroenterol

      Volume: 106 Pages: 1865-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Journal Article] High prevalence of hepatitis C virus infection in Airin district, Osaka, Japan : A hospital-based study of 1162 patients2011

    • Author(s)
      Yamaguchi Y, Enomoto M, Fujii H, Tamori A, Sakaguchi H, Tanigawa T, Watanabe K, Fujiwara Y, Arakawa T, Harihara S, Monna T, Kawada N
    • Journal Title

      Repatol Res

      Volume: 41 Pages: 731-7

    • DOI

      10.1111/j.1872-034x.2011.00834.x

    • NAID

      10031144145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Journal Article] Real-time tissue elastography as a tool for the noninvasive assessment of liver stiffness in patients with chronic hepatitis C2011

    • Author(s)
      Morikawa H, Fukuda K, Kobayashi S, Fujii H, Iwai S, Enomoto M, Tamori A, Sakaguchi H, Kawada N
    • Journal Title

      J Gastroenterol

      Volume: 46 Pages: 350-8

    • NAID

      10029027887

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Journal Article] Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-β-induced inhibition of hepatic stellate cell proliferation2011

    • Author(s)
      Sekiya Y, Ogawa T, Iizuka M, Yoshizato K, Ikeda K, Kawada N.
    • Journal Title

      J Cell Physiol

      Volume: 226 Pages: 2535-42

    • Data Source
      KAKENHI-PROJECT-21390232
  • [Journal Article] Inhibition of pancreatic stellate cell activation by halofuginone prevents pancreatic xenograft tumor development2010

    • Author(s)
      Spector I, Honig H, Kawada N, Nagler A, Genin O, Pines M.
    • Journal Title

      Pancreas

      Volume: 39 Pages: 1008-15

    • Data Source
      KAKENHI-PROJECT-21390232
  • [Journal Article] A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits2010

    • Author(s)
      Ogawa T, Fujii H, Yoshizato K, Kawada N.
    • Journal Title

      Am J Pathol

      Volume: 177 Pages: 153-65

    • Data Source
      KAKENHI-PROJECT-22650224
  • [Journal Article] Inhibition of pancreatic stellate cell activation by halofuginone prevents pancreatic xenograft tumor development2010

    • Author(s)
      Spector I, Honig H, Kawada N, Nagler A, Genin O, Pines M.
    • Journal Title

      Pancreas

      Volume: 39 Pages: 1008-15

    • Data Source
      KAKENHI-PROJECT-22650224
  • [Journal Article] A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits2010

    • Author(s)
      Ogawa T, Fujii H, Yoshizato K, Kawada N
    • Journal Title

      Am J Pathol

      Volume: 177 Pages: 153-65

    • Data Source
      KAKENHI-PROJECT-21390232
  • [Journal Article] Reversibility of fibrosis, inflammation, and endoplasmic reticulum stress in the liver of rats fed a methionine-choline-deficient diet.2010

    • Author(s)
      Mu YP, Ogawa T, Kawada N.
    • Journal Title

      Lab Invest. 90

      Pages: 245-256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390232
  • [Journal Article] Emerging antiviral drugs for hepatitis C virus2009

    • Author(s)
      Enomoto M, Tamori A, Kawada N
    • Journal Title

      Rev Recent Clin Trials

      Volume: 4 Pages: 179-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Journal Article] Emerging antiviral drugs for hepatitis C virus2009

    • Author(s)
      Enomoto M, Tamori A, Kawada N
    • Journal Title

      Rev Recent Clin Trials 4

      Pages: 179-184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Journal Article] Targeted and regulable expression of transgenes in hepatic stellate cells and myofibroblasts in culture and in vivo using an adenoviral Cre/loxP system to antagonise hepatic fibrosis.2007

    • Author(s)
      Kinoshita K, Iimuro Y, Fujimoto J, Inagaki Y, Namikawa K, Kiyama H, Nakajima Y, Otogawa K, Kawada N, Friedman SL, Ikeda K.
    • Journal Title

      Gut 56(3)

      Pages: 396-404

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591513
  • [Journal Article] Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats.2007

    • Author(s)
      Kinoshita K, Iimuro Y, Otogawa K, Saika S, Inagaki Y, Nakajima Y, Kawada N, Fujimoto J, Friedman SL, Ikeda K.
    • Journal Title

      Gut 56(5)

      Pages: 706-14

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591513
  • [Journal Article] Human hepatic stellate cells are resistant to apoptosis : implications for human fibrogenic liver disease.2006

    • Author(s)
      Kawada N.
    • Journal Title

      Gut. 55(8)

      Pages: 1073-1074

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390376
  • [Journal Article] BMP-7 opposes TGF-beta1-mediated collagen induction in mouse pulmonary myofibroblasts through Id2.2006

    • Author(s)
      Izumi N, Mizuguchi S, Inagaki Y, Saika S, Kawada N, Nakajima Y, Inoue K, Suehiro S, Friedman SL, Ikeda K.
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol. 290(1)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590618
  • [Journal Article] BMP-7 opposes TGF-betal-mediated collagen induction in mouse pulmonary myofibroblasts through Id2.2006

    • Author(s)
      Izumi N, Mizuguchi S, Inagaki Y, Saika S, Kawada N, Nakajima Y, Inoue K, Suehiro S, Friedman SL, Ikeda K.
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol. 290(1)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390376
  • [Journal Article] Rho kinases regulate endothelial invasion and migration during valvuloseptal endocardial cushion tissue formation.2006

    • Author(s)
      Sakabe M, Ikeda K, Nakatani K, Kawada N, Imanaka-Yoshida K, Yoshida T, Yamagishi T, Nakajima Y.
    • Journal Title

      Dev Dyn. 235(1)

      Pages: 94-104

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390376
  • [Journal Article] Cancer serum proteomics in gastroenterology.2006

    • Author(s)
      Kawada N
    • Journal Title

      Gastroenterology 130

      Pages: 1917-1919

    • Data Source
      KAKENHI-PROJECT-18659214
  • [Journal Article] Human hepatic stellate cells are resistant to apoptosis : implications for human fibrogenic liver disease.2006

    • Author(s)
      Kawada N
    • Journal Title

      Gut 55

      Pages: 1073-1074

    • Data Source
      KAKENHI-PROJECT-18659214
  • [Journal Article] Human hepatic stellate cells are resistant to apoptosis : implications for human fibrogenic liver disease2006

    • Author(s)
      Kawada N
    • Journal Title

      Gut 55(8)

      Pages: 1073-1074

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390376
  • [Journal Article] Analysis of proteins dominantly expressed in hepatic stellate cells of activated phenotype.2005

    • Author(s)
      Kawada N.
    • Journal Title

      Methods Mol Med. 117

      Pages: 371-379

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590618
  • [Journal Article] Analysis of proteins dominantly expressed in hepatic stellate cells of activated phenotype.2005

    • Author(s)
      Kawada N
    • Journal Title

      Methods Mol Med. 117

      Pages: 371-379

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590618
  • [Journal Article] Effect of S-adenosyl-L-methionine on the activation, proliferation and contraction of hepatic stellate cells.2005

    • Author(s)
      Matsui H, Kawada N
    • Journal Title

      Eur J Pharmacol. 509

      Pages: 31-36

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590618
  • [Journal Article] Overexpression of thioredoxin prevents thioacetamide-induced hepatic fibrosis in mice.2005

    • Author(s)
      Okuyama H, Nakamura H, Shimahara Y, Uyama N, Kwon YW, Kawada N, Yamaoka Y, Yodoi J.
    • Journal Title

      J Hepatol. 42(1)

      Pages: 117-123

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390376
  • [Journal Article] Effect of S-adenosyl-L-methionine on the activation, proliferation and contraction of hepatic stellate cells.2005

    • Author(s)
      Matsui H, Kawada N.
    • Journal Title

      Eur J Pharmacol. 509(1)

      Pages: 31-36

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590618
  • [Journal Article] Cell type-specific intervention of transforming growth factor beta/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice.2005

    • Author(s)
      Inagaki Y, Kushida M, Higashi K, Itoh J, Higashiyama R, Hong YY, Kawada N, Namikawa K, Kiyama H, Bou-Gharios G, Watanabe T, Okazaki I, Ikeda K.
    • Journal Title

      Gastroenterology. 129(1)

      Pages: 259-268

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590618
  • [Journal Article] Structural characterization of the proximal and distal histidine environment of cytoglobin and neuroglobin.2005

    • Author(s)
      Sawai H, Makino M, Mizutani Y, Ohta T, Sugimoto H, Uno T, Kawada N, Yoshizato K, Kitagawa T, Shirro Y
    • Journal Title

      Biochemistry. 44(40)

      Pages: 13257-13265

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590618
  • [Journal Article] Effect of S-adenosyl-L-methionine on the activation, proliferation and contraction of hepatic stellate cells.2005

    • Author(s)
      Matsui H, Kawada N.
    • Journal Title

      Eur J Pharmacol. 509

      Pages: 31-36

    • Data Source
      KAKENHI-PROJECT-16590618
  • [Journal Article] Overexpression of thioredoxin prevents thioacetamide-induced hepatic fibrosis in mice.2005

    • Author(s)
      Okuyama H, Nakamura H, Shimahara Y, Uyama N, Kwon YW, Kawada N, Yamaoka Y, Yodoi J.
    • Journal Title

      J Hepatol. 42(1)

      Pages: 117-123

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590618
  • [Journal Article] Overexpression of thioredoxin prevents acute hepatitis caused by thioacetamide or lipopolysaccharide in mice.2003

    • Author(s)
      H.Okuyama, H.Nakamura, Y.Shimahara, S.Araya, N.Kawada, Y.Yamaoka, J.Yodoi
    • Journal Title

      Hepatology 37

      Pages: 1015-1025

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370355
  • [Journal Article] Regulation of Cultured Rat Hepatocyte Proliferation by Stellate Cells.2002

    • Author(s)
      Uyama-N., Shimahara-Y., Kawada-N., Seki-S., Okuyama-H., Iimuro-Y., Yamaoka-Y.
    • Journal Title

      Journal of Hepatology 36

      Pages: 590-599

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13557100
  • [Journal Article] The hepatic stellate cell in the post-genomic era.2002

    • Author(s)
      H.Okuyama, Y.Shimahara, N.Kawada
    • Journal Title

      Histology and Histopathology 17

      Pages: 487-495

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370355
  • [Journal Article] Regulation of Cultured Rat Hepatocyte Proliferation by Stellate Cells.2002

    • Author(s)
      N.Uyama, Y.Shimahara, N.Kawada, S.Seki, H.Okuyama, Y.Iimuro Y.Yamaoka
    • Journal Title

      J Hepatol 36

      Pages: 590-599

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370355
  • [Journal Article] Characterization of a stellate cell activation-associated protein (S TAP) with peroxidase activity found in rat hepatic stellate cells.2001

    • Author(s)
      Kawada, -N., Kristensen, -D.-B., Asahina, -K., Nakatani, -K., Minamiyama, -Y., Seki, -S., Yoshizato,-K.
    • Journal Title

      J-Biol-Chem. 276(27)

      Pages: 25318-25323

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13557100
  • [Journal Article] Regulation of cell growth by redox-mediated extracellular proteolysis of platelet-derived growth factor receptor beta.2001

    • Author(s)
      Okuyama, -H., Shimahara, -Y., Kawada, -N., Seki, -S., Kristensen, -D.-B., Yoshizato, -K., Uyama, -N., Yamaoka,-Y.
    • Journal Title

      J-Biol-Chem. 276(30)

      Pages: 28274-28280

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13557100
  • [Journal Article] N-acetyl cysteine inhibits PDGF-dependent proliferation of primary cultured o rat hepatic stellate cells through degradation of PDGF receptor and attenuates progress of liver fibrosis in rat models.2001

    • Author(s)
      Okuyama-H., Kawada-N., Shim ahara-Y., Uyama-N., Yamaoka-Y.
    • Journal Title

      Cells of Hepatic Sinusoid 8

      Pages: 284-276

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13557100
  • [Journal Article] The interaction between hepatocytes and stellate cells on individual cell proliferation and differentiation2001

    • Author(s)
      Uyama-N., Kawada-N., Ikuyama-H., Iimuro-Y., Kaneda-K., Shimahara-Y., Yamaoka-Y.
    • Journal Title

      Cells of Hepatic Sinusoid 8

      Pages: 51-54

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13557100
  • [Patent] 抗線維化剤2017

    • Inventor(s)
      河田則文、池田一雄、松原勤、松原三佐子
    • Industrial Property Rights Holder
      河田則文、池田一雄、松原勤、松原三佐子
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Acquisition Date
      2019
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Patent] 肝線維症の存在及び/又は肝線維症の重症度の判定方法、判定マーカー、判定用キット、肝線維症の治療の効果予測方法、効果予測マーカー、並びに効果予測用キット2010

    • Inventor(s)
      河田則文、榎本大、小川智弘
    • Industrial Property Rights Holder
      公立大学法人大阪市立大学
    • Industrial Property Number
      2010-281254
    • Filing Date
      2010-12-17
    • Data Source
      KAKENHI-PROJECT-22650224
  • [Patent] サイトグロビン遺伝子ノックアウト非ヒト癌モデル動物2010

    • Inventor(s)
      河田則文
    • Industrial Property Rights Holder
      河田則文
    • Filing Date
      2010-03-09
    • Data Source
      KAKENHI-PROJECT-21390232
  • [Patent] サイトグロビン遺伝子ノックアウト非ヒト癌モデル動物2010

    • Inventor(s)
      河田則文
    • Industrial Property Rights Holder
      河田則文
    • Industrial Property Number
      2010-052244
    • Filing Date
      2010-03-09
    • Data Source
      KAKENHI-PROJECT-21390232
  • [Patent] 肝線維症の存在及び/又は肝線維症の重症度の判定方法、判定マーカー、判定用キット、肝線維症の治療の効果予測方法、効果予測マーカー、並びに効果予測用キット2010

    • Inventor(s)
      河田則文、榎本大、小川智弘
    • Industrial Property Rights Holder
      公立大学法人大阪市立大学
    • Industrial Property Number
      2010-281254
    • Filing Date
      2010-12-17
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Patent] サイトグロビン遺伝子ノックアウト非ヒト癌モデル動物2010

    • Inventor(s)
      河田則文
    • Industrial Property Rights Holder
      河田則文
    • Filing Date
      2010-03-09
    • Data Source
      KAKENHI-PROJECT-22650224
  • [Patent] 肝線維症の存在及び/又は肝線維症の重症度の判定方法、判定マーカー、判定用キット、肝線維症の治療の効果予測方法、効果予測マーカー、並びに効果予測用キット2010

    • Inventor(s)
      河田則文、榎本大、小川智弘
    • Industrial Property Rights Holder
      公立大学法人大阪市立大学
    • Industrial Property Number
      2010-281254
    • Filing Date
      2010-12-17
    • Data Source
      KAKENHI-PROJECT-21390232
  • [Patent] サイトグロビン遺伝子ノックアウト非ヒト癌モデル動物2010

    • Inventor(s)
      河田則文
    • Industrial Property Rights Holder
      河田則文
    • Filing Date
      2010-03-09
    • Data Source
      KAKENHI-PROJECT-21390232
  • [Presentation] Renal Shear Wave Velocity Measurement can Predict the Response to Tolvaptan Treatment for Hepatic Ascites2019

    • Author(s)
      Hiroyuki Motoyama, Koji Rinka, Ayane Kasamatsu, Hiroko Ikenaga, Maito Suoh, Naoshi Odagiri, Kanako Yoshida, Kohei Kotani, Atsushi Hagihara, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori, Norifumi Kawada
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Selective overexpression of Cytoglobin in stellate cells attenuates their activation and fibrosis development in mice2019

    • Author(s)
      Ninh Quoc Dat,河田則文
    • Organizer
      第55回 日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] 成因不明の肝疾患に対するTransient elastographyの使用経験2019

    • Author(s)
      藤井英樹,森川 浩安, 河田 則文
    • Organizer
      第55回 日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Noninvasive Assessment of Portal Hemodynamics Using Per-Rectal Portal Scintigraphy: A Comparison with Hepatic Venous Pressure Gradient2019

    • Author(s)
      Kohei Kotani, Sawako Uchida-Kobayashi, Naoshi Odagiri, Kanako Yoshida, Hiroyuki Motoyama, Atsushi Hagihara, Hideki Fujii, Masaru Enomoto1, Shinichi Hamamoto, Atsushi Jogo, Akira Yamamoto, Shigeaki Higashiyama, Joji Kawabe, Akihiro Tamori, Norifumi Kawada
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] 保険診療下におけるパンジェノ型抗HCV治療の効果と安全性―他施設共同研究・第2報―2019

    • Author(s)
      田守昭博,榎本大,河田則文
    • Organizer
      第55回 日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Identification of Gut Bacteria Involved in Hepatic Encephalopathy by the Analysis of Rifaximin Administrated Patients2019

    • Author(s)
      Yoshimi Yukawa, Naoko Ohtani, Norifumi Kawada
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] 肝表面直下の血流評価による門脈圧亢進症診断2019

    • Author(s)
      打田佐和子,菊川 佳菜子, 河田 則文
    • Organizer
      第55回 日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] リファキシミンの使用経験と腸内細菌叢に与える影響2019

    • Author(s)
      湯川芳美,大谷直子,河田則文
    • Organizer
      第105回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] TGF-βとサイトグロビンの拮抗作用はヒトNASHにおける星細胞活性化と肝線維化に影響する2019

    • Author(s)
      翁良徳、松原三佐子、藤井英樹、河田則文
    • Organizer
      第55回 日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Histological Evaluations after Achieving a Sustained Virologic Response to DirectActing Antiviral Treatment for Chronic Hepatitis C in a Short Term2019

    • Author(s)
      Masaru Enomoto, Yutaka Yasui, Misako Sato-Matsubara, Yoshihiro Ikura, Akihiro Tamori, Ritsuzo Kozuka, Etsushi Kawamura, Atsushi Hagihara, Hideki Fujii1, Sawako Uchida-Kobayashi, Yoshiki Murakami, Norifumi Kawada
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] 切除不能肝細胞癌に対する 1 次から 3 次治療の全身化学療法としてのレンバチニブ治療2019

    • Author(s)
      周防舞仁, 萩原 淳司, 笠松 彩音, 岡田 雅子, 小田桐 直志, 吉田 香奈子, 小谷 晃平, 元山 宏行, 藤井 英樹, 打田 佐和子, 榎本 大, 森川 浩安, 村上 善基, 田守 昭博, 新川 寛二, 田中 肖吾, 竹村 茂一, 久保 正二, 河田 則文
    • Organizer
      第55回 日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Prospective Multicenter study of Glecaprevir plus Pibrentasvir combination therapy for patients with chronic hepatitis C2019

    • Author(s)
      Tamori A, Iwasa M, Inoue K, Kagawa T, Takaguchi K, Minami M, Iwasaki Y, Nouso K, Hai H, Enomoto M, Kawada N.
    • Organizer
      54th European Association for the study of the liver diseases (Vienna)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Wisteria Floribunda Agglutinin Positive MAC-2-Binding Protein Predicts Esophagogastric Varices in Cirrhotic Patients with Chronic Hepatitis C Virus Infection Treated with IFN-Free Direct-Acting Antiviral Agent2019

    • Author(s)
      Sawako Uchida-Kobayashi, Kanako Kikukawa, Akihiro Tamori, Naoshi Odagiri, Kanako Yoshida, Kohei Kotani, Hiroyuki Motoyama, Atsushi Hagihara, Hideki Fujii, Masaru Enomoto, Norifumi Kawada
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] TGF-β1 transcriptionally repressed cytoglobin expression and enhanced H2O2-induced oxidative DNA damage in activated HSCs.2019

    • Author(s)
      Misako Sato-Matsubara, Yoshinori Okina, Tsutomu Matsubara, Atsuko Daikoku1, Krista Rombouts, Le Thi Thanh Thuy, Hideki Fujii1, Kazuo Ikeda, Katsutoshi Yoshizato, Massimo Pinzani, and Norifumi Kawada
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Standardized uptake valueを用いたアシアロシンチグラフィによる新たな肝予備能評価2019

    • Author(s)
      小谷晃平,打田 佐和子, 小田桐 直志, 吉田 香奈子, 元山 宏行, 藤井 英樹, 萩原 淳司, 森川 浩安, 榎本 大, 田守 昭博, 河田 則文
    • Organizer
      第55回 日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Recombinant Human Cytoglobin Protects Mice from Chemical Induced Liver Fibrosis2019

    • Author(s)
      Ninh Quoc Dat, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Dinh Viet Hoang, Katsutoshi Yoshizato, Norifumi Kawada
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Does liver cirrhosis regress? Consideration based on DAA therapy to type C advanced chronic liver disease in Japan2019

    • Author(s)
      Kawada N.
    • Organizer
      CHESS Forum 2019 for Portal Hypertension
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Cytoglobin suppresses liver fibrosis and cancer in mice by regulating oxidative stress2019

    • Author(s)
      Le Thi Thanh Thuy, Ninh Quoc Dat, Hoang Hai, Dinh Viet Hoang, Katsutoshi Yoishizato and Norifumi Kawada
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Cytoglobin suppresses liver fibrosis and cancer in mice by regulating oxidative stress2019

    • Author(s)
      Thi Le,河田 則文
    • Organizer
      第55回 日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] DAA治療過去4年間からみた治療不成功因子の検討2019

    • Author(s)
      吉田香奈子,田守昭博,河田則文
    • Organizer
      第55回 日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] 肝炎ウイルス制御下における組織学的な脂肪沈着の程度と関連因子の検討2019

    • Author(s)
      岡田雅子,小谷 晃平, 田守 昭博, 笠松 彩音, 周防 舞仁, 小田桐 直志, 吉田 香奈子, 元山 宏行, 藤井 英樹, 打田 佐和子, 榎本 大, 村上 善基, 河田 則文
    • Organizer
      第55回 日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Putative Role of ERK1/2 Signaling of Senescent Human Hepatic Stellate Cells in Hepatocellular Carcinoma derived from Liver Cirrhosis.2019

    • Author(s)
      Naoshi Odagiri, Tsutomu Matsubara, Kazuo Ikeda, Norifumi Kawada
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Downregulation of Cytoglobin by TGF-β Leads to Hydroxyl Radical-induced Oxidative DNA Damage in Human HSCs.2019

    • Author(s)
      Yoshinori Okina, Misako Sato-Matsubara, Tsutomu Matsubara, Atsuko Daikoku, Hideki Fujii, Kazuo Ikeda, Katsutoshi Yoshizato, Massimo Pinzani, Norifumi Kawada
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Role of cytoglibin, the fourth globin in mammals, in liver diseases.2019

    • Author(s)
      Le Thi Thanh Thuy, Hoang Hai, and Norifumi Kawada
    • Organizer
      VJST2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Deletion Mutations in HCV NS5A Persist and Resist to Subsequent Treatment2019

    • Author(s)
      Hai H, Tamori A, Thuy LTT, Yoshida K, Uchida-Kobayashi S, Enomoto M, Kozuka R, Motoyama H, Murakami Y, Kawada N.
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] HCV genotype2型に対するDAA治療の効果と安全性に関する薬剤レジメンの比較2019

    • Author(s)
      和田 響子, 田守 昭博, 小谷 晃平, 吉田 香奈子, 元山 宏行, 藤井 英樹, 石津 弘隆, 萩原 淳司, 打田 佐和子, 森川 浩安, 榎本 大, 村上 善基, 河田 則文
    • Organizer
      第55回 日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Direct-Acting Antiviral Treatment can Prolong Disease-free Survival after Curative Treatment of HCV-related, Primary Hepatocellular Carcinoma in Patient with Advanced Fibrosis2019

    • Author(s)
      Hiroko Ikenaga, SawakoUchida-Kobayashi, Naoshi Odagiri, Kanako Yoshida, Kohei Kotani, Hiroyuki Motoyama, Atsushi Hagihara, Hideki Fuji, Masaru Enomoto, Akihiro Tamori, Norifumi Kawada
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Profiling of Circulating Immune Checkpoint Proteins in Advanced HCC Patients2019

    • Author(s)
      Minh Phuong Dong, Masaru Enomoto, Thi Thanh Thuy Le, Hai Hoang, Atsushi Hagihara, Sawako Uchida-Kobayashi, Akihiro Tamori, Norifumi Kawada
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Identification of gut bacteria involved in hepatic encephalopathy from the analysis of patients administered rifaximin2019

    • Author(s)
      Yoshimi Yukawa Muto, Tomonori Kamiya, Shinji Fukuda, Norifumi Kawada , Naoko Ohtani
    • Organizer
      Cold Spring Harbor Asia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Establishment of Orthotopic Hepatocellular Carcinoma on the Background of Fibrosis by Intrahepatic and Intrasplenic Tumor Inoculation in Mice.2019

    • Author(s)
      Hoang Huu Truong1, Misako Sato-Matsubar, Thuy Thi Thanh Le, Tsutomu Matsubara, Hai Hoang, Atsuko Daikoku, Yoshinori Okina, Hoang Viet Dinh, Norifumi Kawada
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Identification of Lawsone as an Anti-fibrotic Agent based on High-Throughput Screening System with Human COL1A2 Promoter Activity.2019

    • Author(s)
      Misako Sato-Matsubara, Tsutomu Matsubara, Atsuko Daikoku, Kazuo Ikeda, Katsutoshi Yoshizato, Norifumi Kawada
    • Organizer
      JSH international Liver Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03641
  • [Presentation] Establishing efficient systems to promote intra-hospital referrals of hepatitis virus carriers to hepatology specialists2018

    • Author(s)
      M Enomoto, S Uchida, N Kawada
    • Organizer
      JDDW2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Presentation] 肝細胞と肝星細胞の共培養による肝星細胞の活性化制御2018

    • Author(s)
      松原三佐子、松原勤、宇留島隼人、大黒敦子、森浦芳枝、門野千穂、池田一雄、河田則文、吉里勝利
    • Organizer
      第25回 肝細胞研究会
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Presentation] Protective role of hepatic stellate cell-specific overexpression of cytoglobin against liver fibrosis in in vitro and in vivo2018

    • Author(s)
      Nguyen Thi Thanh Hai, Le Thi Thanh Thuy, 河田 則文
    • Organizer
      第54回 日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Presentation] 抗線維化治療法の開発を目指したCytoglobin発現制御機構の解明2018

    • Author(s)
      翁 良徳, 松原 三佐子, 河田 則文
    • Organizer
      第54回 日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Presentation] “Normal” ALT by central laboratory criteria but >30 U/L for males and >19 U/L for females is predictive of residual inflammation in liver biopsies after sustained virologic response to direct-acting antivirals for chronic hepatitis C2018

    • Author(s)
      Masaru Enomoto, Yoshihiro Ikura, Akihiro Tamori, Ritsuzo Kozuka, Hiroyuki Motoyama, Etsushi Kawamura, Atsushi Hagihara, Hideki Fujii, Sawako Uchida-Kobayashi, Hiroyasu Morikawa, Yoshiki Murakami, Norifumi Kawada
    • Organizer
      69th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Presentation] DAAs治療非著効後のHCVウイルスから見た再治療戦略2018

    • Author(s)
      田守昭博、Hoang Hai、河田則文
    • Organizer
      第104回 日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Presentation] Neither MICA nor TLL1 polymorphisms associated with hepatocellular carcinoma after HCV eradication by IFN-free therapies2018

    • Author(s)
      Hoang Hai, 田守 昭博, 河田 則文
    • Organizer
      第54回 日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Presentation] 肝星細胞におけるTGF-β1/Smadシグナルを介したCytoglobin発見制御機構2017

    • Author(s)
      松原三佐子、翁良徳、松原勤、大黒敦子、池田一雄、吉里勝利、河田則文
    • Organizer
      第31回肝類洞壁細胞研究会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Presentation] 肝星細胞を標的とした細胞表面抗原の樹立2017

    • Author(s)
      吹田 安佐詠, 松原 三佐子, 松原 勤, 池田 一雄, 河田 則文
    • Organizer
      第53回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Presentation] C型慢性肝疾患に対するDAA治療前後の肝病理組織所見の変化について2017

    • Author(s)
      榎本大、伊倉義弘 、元山宏行 、小塚立蔵 、萩原淳司、藤井英樹、打田佐和子、森川浩安、村上善基、田守昭博、河田則文
    • Organizer
      第24回日本門脈圧亢進症学会総会
    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Presentation] DAA治療による肝線維化改善効果:非侵襲的評価、病理学的検討を含めて2017

    • Author(s)
      榎本大、村上善基、河田則文
    • Organizer
      第21回日本肝臓学会大会
    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Presentation] C型慢性肝疾患に対するDAA治療前後の短期的肝線維化改善効果について2017

    • Author(s)
      榎本大、田守昭博、河田則文
    • Organizer
      第53回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Presentation] グロビンファミリーの第4のタンパク質であるcytoglobinは胆汁鬱滞誘発性肝障害に対して一酸化窒素調節を介して保護作用を発揮する(Cytoglobin, the fourth member of globin family, protects cholestasis induced liver injury throughout regulation of Nitric oxide)(英語)2017

    • Author(s)
      Le Thi Thanh Thuy, 河田 則文
    • Organizer
      第53回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Presentation] Changes in clinical and histological parameters predictive of liver fibrosis and/or HCC development after direct-acting antiviral treatment for chronic hepatitis C2017

    • Author(s)
      M Enomoto, A Tamori, R Kozuka, H Motoyama, A Hagihara, H Fujii, S Uchida-Kobayashi, H Morikawa, Y Murakami, N Kawada
    • Organizer
      Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Presentation] Regulation of liver carcinogenesis by high fat diet,bile acid,and antibiotics in Cygb knockout mice2017

    • Author(s)
      Le Thi Thanh Thuy、Toung Thi Van Thuy、Hoang Hai、吉里勝利、河田則文
    • Organizer
      第31回肝類洞壁細胞研究会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Presentation] 肝星細胞を標的とした抗線維化治療薬の開発2017

    • Author(s)
      松原 三佐子, 翁 良徳, 河田 則文
    • Organizer
      第53回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Presentation] ヒト肝星細胞におけるTGF-β1/Smadシグナルを介したCytoglobin発現制御機構2017

    • Author(s)
      翁良徳,松原三佐子,河田則文
    • Organizer
      第21回日本肝臓学会大会(JDDW2017)
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Presentation] Short-term histological evaluations after achieving a sustained virological response to direct-acting antiviral treatment for chronic hepatitis C2017

    • Author(s)
      Masaru Enomoto, Akihiro Tamori, Ritsuzo Kozuka, Hiroyuki Motoyama, Atsushi Hagihara, Hideki Fujii, Sawako Uchida-Kobayashi, Hiroyasu Morikawa, Yoshiki Murakami, Yoshihiro Ikura, Norifumi Kawada
    • Organizer
      68th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Presentation] FGF2はCytoglobinとαSMA遺伝子発現を制御し肝星細胞の脱活性化を促進する2016

    • Author(s)
      松原三佐子, 大黒敦子, 松原勤, 池田一雄, 吉里勝利, 河田則文
    • Organizer
      第23回肝細胞研究会
    • Place of Presentation
      大阪大学中之島センター
    • Year and Date
      2016-07-07
    • Data Source
      KAKENHI-PROJECT-16H05290
  • [Presentation] C型慢性肝疾患に対するIFNフリーDAA治療前後の門脈圧に関連する検査値の変化について2016

    • Author(s)
      榎本大、田守昭博、寺西優雅、元山宏行、小塚立蔵、川村悦史、萩原淳司、打田佐和子、森川浩安、村上善基、河田則文
    • Organizer
      第23回日本門脈圧亢進症学会総会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2016-09-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Presentation] Sequential therapy with short-term entecavir followed by interferon in chronic hepatitis B patients2016

    • Author(s)
      M.Enomoto, A.Tamori, R.Kozuka, S.Uchida-Kobayashi, S.Fukunisi, Y.Tsuda, K.Higuchi, M.Saito, H.Enomoto, S.Nishiguchi, N.Kawada
    • Organizer
      25th Conference of the Asian Pacific Associaton for the Study of the Liver (APASL)
    • Place of Presentation
      Grand Prince Hotel New Takanawa, Minato-ku, Tokyo, Japan
    • Year and Date
      2016-02-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461006
  • [Presentation] Changes in NS3/4A and NS5A resistance-associated variants of hepatitis C virus after treatment failure with direct-acting antiviral(s)2016

    • Author(s)
      Hai H, Yoshida K, Tamori A, Enomoto M, Morikawa H, Kozuka R, Teranishi Y, Motoyama H, Kawamura E, Hagihara A, Murakami Y, Thuy LTT, Kawada N
    • Organizer
      AASLD 2016 Annual Meeting
    • Place of Presentation
      Boston, MA, USA
    • Year and Date
      2016-11-11
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860522
  • [Presentation] Promotion of intra-hospital referral of hepatitis B and C virus carriers to hepatology specialists by electronic medical record-based alert system: a case study at a university hospital2016

    • Author(s)
      M. Enomoto, S. Uchida-Kobayashi, H. Fujii, A. Iida-Ueno, H. Motoyama, R. Kozuka, A. Hagihara, E. Kawamura, H. Morikawa, Y. Murakami, A. Tamori, N. Kawada
    • Organizer
      24th United European Gastroenterology Week (UEGW)
    • Place of Presentation
      ウイーン(オーストリア)
    • Year and Date
      2016-10-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Presentation] 当院および関連施設におけるC型肝炎ウイルス感染者の拾い上げに向けた取り組み2016

    • Author(s)
      榎本大、森川浩安、河田則文
    • Organizer
      第41回日本肝臓学会東部会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2016-12-08
    • Data Source
      KAKENHI-PROJECT-16K09369
  • [Presentation] エンテカビル効果不良のHBeAg陽性B型慢性肝疾患に対するHBワクチン併用の試み 無作為比較試験2015

    • Author(s)
      榎本 大, 木岡 清英, 田守 昭博, 寺西 優雅, 小塚 立蔵, 元山 宏行, 川村 悦史, 萩原 淳司, 打田 佐和子, 森川 浩安, 村上 善基, 河田 則文
    • Organizer
      第41回日本肝臓学会西部会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-25461006
  • [Presentation] エンテカビル効果不良の難治性B型慢性肝疾患の特徴とその対策2015

    • Author(s)
      榎本 大, 田守 昭博, 河田 則文
    • Organizer
      第51回日本肝臓学会総会
    • Place of Presentation
      ホテル日航熊本ほか(熊本県熊本市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25461006
  • [Presentation] B型慢性肝炎に対する短期エンテカビル先行投与後/PEG-IFN sequential療法の有効性2015

    • Author(s)
      榎本 大, 田守 昭博, 小塚 立蔵, 打田 佐和子, 福西 新弥, 津田 泰宏, 樋口 和秀, 齋藤 正紀, 榎本 平之, 西口 修平, 河田 則文
    • Organizer
      第19回日本肝臓学会大会
    • Place of Presentation
      グランドプリンスホテル新高輪ほか(東京都港区)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25461006
  • [Presentation] Evolution of hepatic fibrosis reserch2015

    • Author(s)
      Kawada N
    • Organizer
      Asian Pacific Association for the Study of the Liver
    • Place of Presentation
      Istanbul (Turkey)
    • Year and Date
      2015-03-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293177
  • [Presentation] Loss of Cytoglobin Exacerbates Liver Fibrosis and Cancer Development in Steatohepatitis by Activating the Oxidative Stress Pathway2015

    • Author(s)
      Le, Thuy T、Matsumoto, Yoshinari、Tuong Thi Van Thuy、Hoang Hai、Yoshizato, Katsutoshi、Kawada, Norifumi
    • Organizer
      American Association for the Study of Liver Diseases
    • Place of Presentation
      San Francisco(U S A)
    • Year and Date
      2015-11-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293177
  • [Presentation] MICA SNP, but not DEPDC5, PNPLA3 and HCP5 SNPs, is associated with chronic hepatitis C-related hepatocellular carcinoma2015

    • Author(s)
      Hoang Hai, Akihiro Tamori, Kanako Yoshida, Atsushi Hagihara, Etsushi Kawamura, Sawako K. Uchida, Hiroyasu Morikawa, Masaru Enomoto, Yoshiki Murakami, Thuy T. Le, Norifumi Kawada.
    • Organizer
      AASLD Annual Meeting.
    • Place of Presentation
      サンフランシスコ(アメリカ合衆国)
    • Year and Date
      2015-11-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860522
  • [Presentation] 慢性肝疾患における肝線維化バイオマーカーとしてのmiR-222の有用性2013

    • Author(s)
      河田 則文, 小川 智弘, 榎本大, 藤井 英樹, 村上 善基, 吉里 勝利, 池田 一雄
    • Organizer
      第50回日本臨床分子医学会学術集会
    • Place of Presentation
      東京(東京国際フォーラム)
    • Data Source
      KAKENHI-PROJECT-25461006
  • [Presentation] 前向き登録例の長期経過からみたHBV再活性化対策の現状2013

    • Author(s)
      田守 昭博, 榎本 大, 河田 則文
    • Organizer
      第17回日本肝臓学会大会
    • Place of Presentation
      東京(グランドプリンスホテル新高輪)
    • Data Source
      KAKENHI-PROJECT-25461006
  • [Presentation] B型慢性肝炎に対するPEG-IFNの早期抗ウイルス効果:Sequential療法も含めて2013

    • Author(s)
      榎本 大, 田守 昭博, 河田 則文
    • Organizer
      第17回日本肝臓学会大会
    • Place of Presentation
      東京(グランドプリンスホテル新高輪)
    • Data Source
      KAKENHI-PROJECT-25461006
  • [Presentation] Cytoglobin as a novel tumor suppressor in the liver2011

    • Author(s)
      Kawada N
    • Organizer
      Le TT. AASLD
    • Place of Presentation
      サンフランシスコ、USA
    • Year and Date
      2011-11-04
    • Data Source
      KAKENHI-PROJECT-21390232
  • [Presentation] Indication of the Activation of Stellate Cells and the Progression of Liver Fibrosis by MicroRNA-2222011

    • Author(s)
      Enomoto M, Ogawa T, Iizuka M, Fujii H, Tamori A, Yoshizato K, Ikeda K, Kawada N
    • Organizer
      62^<nd> Annual Meeting of the American Association for the Study of Liver Diseases(AASLD)
    • Place of Presentation
      San Francisco, CA
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Presentation] Indication of the Activation of Stellate Cells and the Progression of Liver Fibrosis by MicroRNA-2222011

    • Author(s)
      Enomoto M, Ogawa T, Iizuka M, Fujii H, Tamori A, Yoshizato K, Ikeda K, Kawada N
    • Organizer
      62^<nd> Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
    • Place of Presentation
      San Francisco, CA
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Presentation] Cytoglobin as a novel tumor suppressor in the liver2011

    • Author(s)
      Kawada N
    • Organizer
      Le TT. AASLD
    • Place of Presentation
      サンフランシスコ、USA
    • Year and Date
      2011-11-04
    • Data Source
      KAKENHI-PROJECT-22650224
  • [Presentation] 肝線維化と星細胞活性化に関与するマイクロRNAの解析2011

    • Author(s)
      飯塚昌司、小川智弘、関谷由美子、榎本大、吉里勝利、池田一雄、河田則文
    • Organizer
      第15回日本肝臓学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Presentation] 慢性肝疾患における肝線維化診断マーカーとしてのmiR-222の有用性2011

    • Author(s)
      飯塚昌司、榎本大、小川智弘、藤井英樹、小林佐和子、岩井秀司、森川浩安、田守昭博、河田則文
    • Organizer
      第15回日本肝臓学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Presentation] 慢性肝疾患における肝線維化バイオマーカーとしてのマイクロRNAの有用性2011

    • Author(s)
      榎本大、小川智弘、河田則文
    • Organizer
      第39回日本肝臓学会西部会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Presentation] C型慢性肝炎患者における肝線維化診断マーカーとしてのマイクロRNAの有用性2011

    • Author(s)
      小川智弘、榎本大、河田則文
    • Organizer
      第97回日本消化器病学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Presentation] リバビリン投与量と貧血程度からみたペグインターフェロン・リバビリン療法の抗ウイルス効果予測2010

    • Author(s)
      田守昭博、黒岡浩子、藤井英樹、小林佐和子、岩井秀司、森川浩安、榎本大、坂口浩樹、木岡清英、倉井修、岡博子、河田則文
    • Organizer
      第46回日本肝臓学会総会
    • Place of Presentation
      山形市双葉町・山形テルサ
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Presentation] Update of cytoglobin, the newest member of globin that was discovered from the stellate cell2010

    • Author(s)
      Kawada N
    • Organizer
      International Society of Hepatic Sinusoidal Research
    • Place of Presentation
      Pasadena, CA, USA(招待講演)
    • Year and Date
      2010-08-30
    • Data Source
      KAKENHI-PROJECT-22650224
  • [Presentation] セロタイプ2型に対するペグインターフェロン・リバビリン療法の治療期間とSVR率2010

    • Author(s)
      山口康徳、田守昭博、藤井英樹、小林佐和子、岩井秀司、森川浩安、榎本大、坂口浩樹、木岡清英、倉井修、岡博子、河田則文
    • Organizer
      第46回日本肝臓学会総会
    • Place of Presentation
      山形市双葉町・山形テルサ
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Presentation] Update of cytoglobin, the newest member of globin that was discovered from the stellate cell2010

    • Author(s)
      Kawada N
    • Organizer
      International Society of Hepatic Sinusoidal Research
    • Place of Presentation
      Pasadena, CA, USA(招待講演)
    • Year and Date
      2010-08-30
    • Data Source
      KAKENHI-PROJECT-21390232
  • [Presentation] Changes in sequences of core region, ISDR and IRRDR of the HCV genome during interferon alpha and ribavirin therapy2010

    • Author(s)
      Kozuka R, Enomoto M, Hagihara A, Fujii H, Kobayashi S, Iwai S, Morikawa H, Tamori A, Kawada N
    • Organizer
      7th APASL Single Topic Conference
    • Place of Presentation
      千葉市美浜区・幕張メッセ
    • Year and Date
      2010-11-16
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Presentation] ペグインターフェロン・リバビリン療法におけるリバビリン血中濃度と治療期間延長効果の検討2009

    • Author(s)
      黒岡浩子、田守昭博、小林佐和子、岩井秀司、森川浩安、榎本大、倉井修、木岡清英、坂口浩樹、岡博子、羽生大記、塩見進、河田則文
    • Organizer
      第45回 日本肝臓学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Presentation] Pathogenetic Mechanisms of Liver Damage and Fibrosis2009

    • Author(s)
      Kawada N
    • Organizer
      UEGW2009
    • Place of Presentation
      コペンハーゲン デンマーク
    • Year and Date
      2009-04-25
    • Data Source
      KAKENHI-PROJECT-21390232
  • [Presentation] 難治性C型肝炎例に対するペグインターフェロン(Peg-IFN)・リバビリン再治療による抗ウイルス効果2009

    • Author(s)
      田守昭博、小林佐和子、岩井秀司、森川浩安、榎本大、坂口浩樹、木岡清英、岡博子、河田則文
    • Organizer
      第95回 日本消化器病学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2009-05-07
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Presentation] Genotype 1bのC型慢性肝炎に対するPEG-IFN-α/リバビリン投与期間の個別化について:リアルタイムPCRによるresponse-guided therapyの再評価2009

    • Author(s)
      中屋美香、榎本大、林健博、遠山まどか、藤井英樹、小林佐和子、岩井秀司、森川浩安、田守昭博、坂口浩樹、羽生大記、塩見進、河田則文
    • Organizer
      第45回 日本肝臓学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-21590856
  • [Presentation] HBeAg陽性B型慢性肝炎に対する核酸アナログ/IFN sequential治療後の長期経過:特にHBsAg、HBcrAgの変化について

    • Author(s)
      榎本大、西口修平、河田則文
    • Organizer
      第100回日本消化器病学会総会
    • Place of Presentation
      東京国際フォーラム(東京都千代田区)
    • Year and Date
      2014-04-23 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-25461006
  • [Presentation] B型慢性肝炎に対するエンテカビル/IFN sequential療法:特にPEG-IFNと従来型IFNの比較について

    • Author(s)
      榎本 大、齋藤正紀、榎本平之、西口修平、津田泰宏、樋口和秀、打田佐和子、森川浩安、村上善基、田守昭博、河田則文
    • Organizer
      第18回日本肝臓学会大会
    • Place of Presentation
      神戸国際展示場他(神戸市中央区)
    • Year and Date
      2014-10-23 – 2014-10-24
    • Data Source
      KAKENHI-PROJECT-25461006
  • [Presentation] Long-term outcome of sequential therapy with lamivudine followed by interferon in nucleoside-naïve, hepatitis B e antigen-positive patients with chronic hepatitis B virus genotype C infection

    • Author(s)
      M. Enomoto, S. Nishiguchi, A. Tamori, S. Uchida-Kobayashi, S. Iwai, H. Morikawa, Y. Murakami, H. Jomura, S. Shiomi, N. Kawada
    • Organizer
      49th Annual Meeting of the European Association for the Study of the Liver
    • Place of Presentation
      London (England)
    • Year and Date
      2014-04-09 – 2014-04-13
    • Data Source
      KAKENHI-PROJECT-25461006
  • 1.  SHIMAHARA Yasuyuki (30196498)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 7 results
  • 2.  IKEDA Kazuo (80275247)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 5 results
  • 3.  YAMAOKA Yoshio (90089102)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 6 results
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    # of Collaborated Products: 51 results
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    # of Collaborated Products: 19 results
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    # of Collaborated Products: 62 results
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    # of Collaborated Products: 4 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Products: 1 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Products: 2 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  久保 正二 (80221224)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 38.  石川 智久 (10201914)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  濱島 義隆 (40333900)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  山口 桃生 (30804819)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  IWAISAKO keiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  TANAKA shogo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  KINOSHITA masahiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  ITO tokuji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  DAIKOKU atsuko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  ODAGIRI naoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  TAKADA sayuri
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  HIGUCHI moe
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  FUJIWARA Yasuhiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 50.  OHFUJI Satoko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 51.  YONEDA Masato
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 52.  ABE Hiromi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 53.  KORENAGA Masaaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 54.  松原 三佐子(佐藤三佐子)
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 15 results
  • 55.  西本 尚樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 56.  茶山 一彰
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 57.  中島 淳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 58.  今城 健人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 59.  小谷 晃平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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