SHIMAHARA Yasuyuki 蔦原康行

… Alternative Names

Researcher Number	30196498
Other IDs
External Links
Affiliation (based on the past Project Information) *help	1997 – 2005: 京都大学, 医学研究科, 助教授 1999: 京都大学, 大学院・医学研究科, 助教授 1999: 京都大学, 大学院・医学研究科, 教授 1995 – 1996: 愛媛大学, 医学部, 助教授 1993: 愛媛大学, 医学部, 助教授 1987 – 1993: 京都大学, 医学部, 助手
Review Section/Research Field	Principal Investigator General surgery / Digestive surgery / Digestive surgery / General surgery Except Principal Investigator Digestive surgery / Digestive surgery / General surgery / Human pathology
Keywords	Principal Investigator 星細胞 / ROCK / 肝線維化 / 肝不全 / NAC / 肝微小循環 / 生体顕微鏡 / Rho kinase inhibitor / Rho kinase阻害剤 / hepatic microcirculation … More Except Principal Investigator 血中ケトン体比 / 肝切除 / GSSG / 肝切除術 / 肝移植 / LOH / GSH / 遺伝子導入 / 肝ミトコンドリア / エネルギーチャージ / 肝不全 / SIAH1 / サイトカイン / Liver Transplantation / グルタチオン / p53 / Veno-Venous Bypass / PEG10 / reperfusion / mdm2 / 肝硬変 / 肝虚血再灌流障害 / 肝再生 / 動脈血中ケトン体比 / Arterial ketone body ratio / アポトーシス / TaqMan PCR / ケトン体比 / AKBR / 手術侵襲 / Redox理論 / 肝細胞癌 / Hepatic Surgery / 膜電位 / 生物活性 / GHS / 還元型グルタチオン / リンパ球MTT assay / Heat shock protein / 肝エネルギ-代謝 / hepatic failure / viability / apoptosis / グルカゴン / リンパ球MTT活性 / fluorometry / 経門脈投与 / Autotransplantation After Partial Resection / Primary Nonfunction Liver / Ischemia-reperfusion Injury / 胆管細胞癌 / 肝微小循環 / Apoptosis / auto cyto protection / gene transfer / pyridine nucleotides / Hepatectomy / 代謝管理 / 肝再灌流 / 低酸素血症 / 病理学的検討 / 閉塞性黄疸 / 虚血耐性 / 成長ホルモン / Liver cirrhosis / 肝細胞 / 線維化 / 分子シャペロン / 肝組織 / アポプトーシス / Primary Graft Failure / tumor suppressor gene / ischemia / Redox theory / Preconditioning / 生体蛍光顕微鏡 / 体内肝冷却潅流法 / Hyperthermia / Hepatocellular carcinoma / 血中ケトル体比 / 酸化還元状態 / Ischemia / 腸管阻血 / Cold Perfusion Of The Liver In Situ / Ischemic tolerance / autocyto protection / ケトン対比(KBR) / score / mutation / β-カテニン / マイクロサテライト / 肝炎ビールマ / 血中ケトン体比(AKBR) / Living Relared Partial Liver Transplantation / 温熱療法 / マイクロアレイ / hepatic energy metabolism / Cold perfusion in-situ / Racl / 可溶性接着分子 / proliferative cholangitis / 肝エネルギ-チャ-ジ / methylation / partial hepatectomy / 甲状腺ホルモン / 肝冷却潅流 / Initial Non-Functioning Liver / トロトラスト / 肝腫瘍 / Redox 理論 / 脳死ドナ- / 術前評価 / Extended liver Surgery / Viability of The Liver Graft / 胆汁酸 / アデノウイルス / 肝保存 / 増殖性胆管炎 / Redox State / 細胞外マトリックス / Liver resection / Redox state / ミトコンドリア / 生体肝移植 / Fibrosis / intrahepatic cholangiocarcinoma / K-ras / 肝再潅流 / Damaged liver / 移植肝 / Rac1 / 出血 / 虚血再灌流 / hepatoma / 糖代謝 / 接着分子 / HVJ-liposome / 冷却潅流法 / マイクロサテライトマーカー / アセト酢酸 / 拡大肝切除 / Rejection / 肝臓 / 熱ショック蛋白 / 肝移植術 / 肝虚血耐性 / hepatic reperfusion / 再発 / Y-27632 / ストレス蛋白 / Arterial Ketone Body Ratio / Donor Liver Viability / Signal pathway / 腸管うっ血 / 遺伝子変異 / Gene / 腎組織 / Redox Theory / Leptin / インスリン / VenoーVenous Bypass / Arterial Ketone Body Ratio (AKBR) / TGH-beta / microsatellite / 障害肝 / Radical extended hepatectomy / intestinal congestion / genomic instability / autocytoprotection / 虚血再潅流障害 / Hepatic surgical score score / ex situ / 肝機能評価法 / β-catenin / 肝グラフトのViability / 自己肝移植 / 3ヒドロキシ酪酸 / Recurrence / Bio-Pump / 性別 / Glutathione / Thorotrast / 体内肝冷却潅流 / ずり応力 / レプチン / 再潅流 / β-atenin / 根治的広範肝切除 / 肝ミトコンドリア酸化的リン酸化能 / kupffer cell / Lymphocyte MTT assay / 肝機能評価 / P53 / 伊藤細胞 / Liver regeneration / cytokine / shear stress / 酸化型グルタチオン / 遺伝子 / 外科的胆汁うっ滞 / AKBR(血中ケトン体比) / 遺伝子不安定性 / 術後合併症 / グラフトのバイアビリティ / 肝臓外科 / プレコンディショニング / 術中侵襲スコア / liver regeneration / spectro photometry / cDNA microarray / Hepatic Malignancy / 肝虚血 / シグナル伝達 / 虚血再灌流障害 / haplo-insufficiency / 血中炎症性サイトカイン / アミノ酸 / Molecular chaperone / 虚血再灌潅流 / 拒絶反応 / 定量的RT-PCR / 肝切除率 Less

SIAH1の肝発癌における関与の解明と肝癌遺伝子治療の可能性に関する研究
- Principal Investigator
  
  HASEGAWA Suguru
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Improvement of perioperative and postoperative management after hepatic resection for HCC by the regulation of hepatic stellate cells.Principal Investigator
- Principal Investigator
  
  HATANO Etsuro, 嶌原康行
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
The research to establish the recurrence predicting system for hepatocellular carcinoma patients by use of genome-wide microarray database and to identify therapeutic molecular targets
- Principal Investigator
  
  SATOH Seiji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
ストレス応答蛋白チオレドキシンによる新しい術後肝障害防止対策Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
ROCK/Rhoシグナル伝達系制御による肝虚血再潅流障害抑制の新しい治療戦略
- Principal Investigator
  
  SATOH Seiji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Development of perioperative management for hepatic resection based on the stellate cell functionPrincipal Investigator
- Principal Investigator
  
  SHIMAHARA Yasuyuki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
肝細胞・肝星細胞の供培養による細胞増殖相互作用Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
肝線維化疾患におけるKupffer cell選択的遺伝子治療の試み
- Principal Investigator
  
  山本成尚
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Regulation of hepatic micro circulation by hepatic stellate cell-Application of NAC to liver failurePrincipal Investigator
- Principal Investigator
  
  SHIMAHARA Yasuyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  KYOTO UNIVERSITY
N-acetylcysteineによる星細胞活性化の制御Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Strategy for Liver Failure by Regulating Hepatic Microcirculation through Hepatic Stellate Cell ActivatityPrincipal Investigator
- Principal Investigator
  
  SHIMAHARA Yasuyuki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  KYOTO UNIVERSITY
Role of "shear stress" in initiation of liver regeneration
- Principal Investigator
  
  IIMURO Yuji
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  HYOGO COLLEGE OF MEDICINE
  Kyoto University
Activation of regeneration capacity of the cirrhotic livers based on the molecular and genetic biology
- Principal Investigator
  
  YAMAOKA Yoshio
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  KYOTO UNIVERSITY
Aspect of Strategy for Liver Failure by Regelating Hepatic Stellate Cell ActivationPrincipal Investigator
- Principal Investigator
  
  SHIMAHARA Yasuyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  KYOTO UNIVERSITY
ミオグロビン遺伝子導入による肝癌に対する集学的治療法の開発Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Evaluation of Indication for Liver Transplantation in Primary Liver Cancers : Focused on Analysis of Multicentric Liver Cancers and Relapse of Prediction.
- Principal Investigator
  
  FUKUMOTO Manabu
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Human pathology
- Research Institution
  TOHOKU University
New Strategy for Liver Failure by Regulating Hepatic Extracellular MatrixPrincipal Investigator
- Principal Investigator
  
  SHIMAHARA Yasuyuki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  KYOTO UNIVERSITY
The relationship between hepatic failure following hepatectomy and induction of apoptosis and its therapeutic approach
- Principal Investigator
  
  YAMAMOTO Naritaka
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  KYOTO UNIVERSITY
Moduration of the molecular chaperone activity to increase the safety of extended liver surgery in the damaged liver patients -- challenge by the induction of stress response and heat shock gene transfection --
- Principal Investigator
  
  YAMAOKA Yoshio
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  KYOTO UNIVERSITY
細胞死からみた外科侵襲の新たな定量化法の開発
- Principal Investigator
  
  山本成尚
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Ehime University
還元型・酸化型グルタチオン代謝変動からみた肝虚血・再潅流時の侵襲評価に関する研究
- Principal Investigator
  
  小林展章
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Ehime University
敗血症時の多臓器不全防止に対する新しい治療法-NO吸入療法の確立に関する研究Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Ehime University
炎症反応からみた新しい肝機能評価の確立
- Principal Investigator
  
  山本成尚
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Ehime University
肝臓外科において手術侵襲を軽減する手術手技の開発
- Principal Investigator
  
  山岡義生
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
外科的胆汁うっ滞病変における胆汁酸及びグルタチオン代謝変動の意義に関する研究
- Principal Investigator
  
  KOBAYASHI Nobuaki
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Ehime University
ポータブル血中ケトン体測定器の試作
- Principal Investigator
  
  山岡義生
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
Perioperative management in clinical liver traus plantation
- Principal Investigator
  
  YAMAOKA Yoshio, 小澤和恵
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyoto University Faculty of Medicine, The Secoud Department of Surgery
人工肝補助装置を用いた脳死肝,屍体肝viability向上に対する研究Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
成長ホルモン・経門脈インスリン投与による肝切除術後代謝管理法の開発
- Principal Investigator
  
  森敬一郎
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Surgical Treatment for Hepatic Malignancy, In Situ and Ex Situ
- Principal Investigator
  
  YAMAOKA Yoshio
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  KYOTO UNIVERSITY
UW液を用いた人工肝の効率改善に関する研究Principal Investigator
- Principal Investigator
  
  島原康行
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
肝ミトコンドリア機能よりみたグルカゴン投与による新たな肝予備力評価法の開発
- Principal Investigator
  
  森敬一郎
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Evaluation of liver graft viability in human liver transplantation.
- Principal Investigator
  
  OZAWA Kazue
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyoto University
Use of Redox theory in the perioperative metabolic support and the treatment in liver surgery and transplant.
- Principal Investigator
  
  OZAWA Kazue
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
The investigation on the relation between the glutathione metabolism and liver atrophy.
- Principal Investigator
  
  KOBAYASHI Nobuaki
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Ehime University
  Kyoto University
遠心型ポンプを用いた人工肝の効率改善に関する研究Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
生着率の向上を目的とした移植肝viabilityの非侵襲的判定装置の開発
- Principal Investigator
  
  小澤和恵
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
Hepatic Resection Using in-situ Cold Perfusion Under Total Vascular Exclusion
- Principal Investigator
  
  YAMAOKA Yoshio
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
簡便性と安全性の向上を目的とした生物学的肝補助装置の改良Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
肝不全の診断と治療のためのRedox全自動連続分析装置の試作研究
- Principal Investigator
  
  小澤和恵
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
Quantification of operative stress for radical extended hepatectomy
- Principal Investigator
  
  OZAWA Kazue
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  KYOTO UNIVERSITY
外科手術後の多臓器不全における代謝異常と細胞障害の分析
- Principal Investigator
  
  山岡義生
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University

All 2006 2005 2004 2003 2002 2001

All Journal Article

[Journal Article] Prognostic index for patients with hepatocellular carcinoma combined with tumor thrombosis in the major portal vein.2006
- Author(s)
  Ikai I, Hatano E, Hasegawa S, Fujii H, Taura K, Uyama N, Shimahara Y.
- Journal Title
  
  J Am Coll Surg. 202(3)
  
  Pages: 431-438
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] High volume hydrodynamic injection of plasmid DNA via the hepatic artery results in a high level of gene expression in rat hepatocellular carcinoma induced by diethylnitrosamine.2006
- Author(s)
  Tada M, Hatano E, Taura K, Nitta T, Koizumi N, Ikai I, Shimahara Y.
- Journal Title
  
  J Gene Med. 8(8)
  
  Pages: 1018-1026
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Preoperative positron emission tomography with fluorine-18-fluorodeoxyglucose is predictive of prognosis in patients with hepatocellular carcinoma after resection.2006
- Author(s)
  Hatano E, Ikai I, Higashi T, Teramukai S, Torizuka T, Saga T, Fujii H, Shimahara Y.
- Journal Title
  
  World J Surg. 30(9)
  
  Pages: 1735-1741
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Implication of frequent local ablation therapy for intrahepatic recurrence in prolonged survival of patients with hepatocellular carcinoma undergoing hepatic resection : an analysis of 610 patients over 16 years old.2006
- Author(s)
  Taura K, Ikai I, Hatano E, Fujii H, Uyama N, Shimahara Y.
- Journal Title
  
  Ann Surg. 244(2)
  
  Pages: 265-273
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Pancreatic arteriovenous malformation with portal hypertension.2006
- Author(s)
  Hosogi H, Ikai I, Hatano E, Taura K, Fujii H, Yamamoto Y, Shimahara Y.
- Journal Title
  
  J Hepatobiliary Pancreat Surg. 13(4)
  
  Pages: 344-346
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Complete response by a combination of 5-fluorouracil and interferon-alpha chemotherapy for lung metastasis of hepatocellular carcinoma after hepatic resection with portal and hepatic vein tumor thrombectomy.2005
- Author(s)
  Hosogi H, Ikai I, Hatano E, Taura K, Fujii H, Yamamoto N, Shimahara Y.
- Journal Title
  
  Hepatol Res. 33(4)
  
  Pages: 320-324
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Blocking of PI3K/Akt pathway enhances apoptosis induced by SN-38, an active form of CPT-11, in human hepatoma cells.2005
- Author(s)
  Koizumi N, Hatano E, Nitta T, Tada M, Harada N, Taura K, Ikai I, Shimahara Y.
- Journal Title
  
  Int J Oncol. 26(5)
  
  Pages: 1301-1306
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Overexpression of thioredoxin prevents thioacetamide-induced hepatic fibrosis in mice.2005
- Author(s)
  Okuyama H, Nakamura H, Shimahara Y, Uyama N, Kwon YW, Kawada N, Yamaoka Y, Yodoi J.
- Journal Title
  
  J Hepatol. 42(1)
  
  Pages: 117-123
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Suppression of VEGFR-3 signaling inhibits lymph node metastasis in gastric cancer.2004
- Author(s)
  Shimizu K, Kubo H, Yamaguchi K, Kawashima K, Ueda Y, Matsuo K, Awane M, Shimahara Y, Takabayashi A, Yamaoka Y, Satoh S.
- Journal Title
  
  Cancer Sci. 95(4)
  
  Pages: 328-333
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Effectiveness of endoscopic nasobiliary drainage for postoperative bile leakage after hepatic resection.2004
- Author(s)
  Terajima H, Ikai I, Hatano E, Uesugi T, Yamamoto Y, Shimahara Y, Yamaoka Y.
- Journal Title
  
  World J Surg. 28(8)
  
  Pages: 782-786
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Overexpression of thioredoxin prevents acute hepatitis caused by thioacetamide or lipopolysaccharide in mice.2003
- Author(s)
  H.Okuyama, H.Nakamura, Y.Shimahara, S.Araya, N.Kawada, Y.Yamaoka, J.Yodoi
- Journal Title
  
  Hepatology 37
  
  Pages: 1015-1025
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370355
[Journal Article] Reduction of hepatic ischemia/reperfusion-induced injury by a specifi ROCK/Rho kinase inhibitor Y-27632.2003
- Author(s)
  F.Ikeda, H.Terajima, Y.Shimahara, T.Kondo, Y.Yamaoka
- Journal Title
  
  J Surg Res 109(2)
  
  Pages: 155-160
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370355
[Journal Article] The hepatic stellate cell in the post-genomic era.2002
- Author(s)
  H.Okuyama, Y.Shimahara, N.Kawada
- Journal Title
  
  Histology and Histopathology 17
  
  Pages: 487-495
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370355
[Journal Article] Significance of serum type IV collagen level of hepatectomized patients with chronic liver damage.2002
- Author(s)
  Y.Shimahara, N.Yamamoto, N.Uyama, H.Okuyama, H.Momoi, T.Kamikawa, H.Terajima, Y.Iimuro, Y.Yamamoto, I.Ikai, F.Kushihata, H.Kiyochi, N.Kobayashi, Y.Yamaoka
- Journal Title
  
  World J Surg 26(4)
  
  Pages: 451-456
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370355
[Journal Article] Regulation of Cultured Rat Hepatocyte Proliferation by Stellate Cells.2002
- Author(s)
  N.Uyama, Y.Shimahara, N.Kawada, S.Seki, H.Okuyama, Y.Iimuro Y.Yamaoka
- Journal Title
  
  J Hepatol 36
  
  Pages: 590-599
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370355
[Journal Article] Significance of serum type IV collagen level of hepatectomized patients with chronic liver damage.2002
- Author(s)
  Shimahara Y
- Journal Title
  
  World-J-Surg. 26(4)
  
  Pages: 451-456
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557100
[Journal Article] Regulation of Cultured Rat Hepatocyte Proliferation by Stellate Cells.2002
- Author(s)
  Uyama-N., Shimahara-Y., Kawada-N., Seki-S., Okuyama-H., Iimuro-Y., Yamaoka-Y.
- Journal Title
  
  Journal of Hepatology 36
  
  Pages: 590-599
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557100
[Journal Article] Significance of serum type IV collagen level of hepatectomized patients with chronic liver damage.2002
- Author(s)
  Y.Shimahara
- Journal Title
  
  World J Surg 26
  
  Pages: 451-456
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370355
[Journal Article] Significance of serum type IV collagen level of hepatectomized patients with chronic liver damage.2002
- Author(s)
  Shimahara-Y., Yamamoto-N., Uyama-N., et al.
- Journal Title
  
  World J Surg 26(4)
  
  Pages: 451-456
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557100
[Journal Article] The interaction between hepatocytes and stellate cells on individual cell proliferation and differentiation2001
- Author(s)
  Uyama-N., Kawada-N., Ikuyama-H., Iimuro-Y., Kaneda-K., Shimahara-Y., Yamaoka-Y.
- Journal Title
  
  Cells of Hepatic Sinusoid 8
  
  Pages: 51-54
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557100
[Journal Article] Regulation of cell growth by redox-mediated extracellular proteolysis of platelet-derived growth factor receptor beta.2001
- Author(s)
  Okuyama, -H., Shimahara, -Y., Kawada, -N., Seki, -S., Kristensen, -D.-B., Yoshizato, -K., Uyama, -N., Yamaoka,-Y.
- Journal Title
  
  J-Biol-Chem. 276(30)
  
  Pages: 28274-28280
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557100

1. YAMAOKA Yoshio (90089102)

# of Collaborated Projects: 27 results

# of Collaborated Products: 7 results
2. OZAWA Kazue (00026858)

# of Collaborated Projects: 14 results

# of Collaborated Products: 0 results
3. YAMAMOTO Maritaka (30253298)

# of Collaborated Projects: 14 results

# of Collaborated Products: 2 results
4. MORI Keiichiro (80159186)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
5. KAWADA Norihumi (30271191)

# of Collaborated Projects: 9 results

# of Collaborated Products: 7 results
6. KOBAYASHI Nobuaki (60135564)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
7. IIMURO Yuji (30252018)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
8. YAMAMOTO Yuzo (70281730)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
9. TANAKA Kouichi (20115877)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
10. MORIMOTO Taisuke (60135910)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
11. TANAKA Akira (00240820)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
12. IKAI Iwao (60263084)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
13. HONDA Kazuo (00209321)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
14. NAKAMURA Hajime (70303914)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
15. SATOH Seiji (00303834)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
16. HATANO Etsuro (80359801)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
17. TERAJIMA Hiroaki (40314215)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
18. HASEGAWA Suguru (10362500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. ピッケルマイヤールドル

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. ルドルフピッケルマイヤ

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. KINOSHITA Seiichi (10169906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. YAMABE Hirohiko (00135592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. INAMOTO Takashi (10135577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. FUKUMOTO Manabu (60156809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SATOMI Susumu (00154120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. MANABE Noboru (80243070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. YAEGASHI Hiroshi (40182290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. FUJIMOTO Jiro (90199373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. UYAMA Naoki (70402873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
30. KISHIMOTO Michimasa (00144436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. FUKUSHIMA Masanori (80107820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 折井豊 (60028149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 岩川和秀 (30243786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 松田良一 (10243784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 柴田徹 (40293857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 山内清明 (00291427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 尾崎信弘 (50211818)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 松井茂之 (80305854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 長村俊彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 森尚樹

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 青木吉平

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 宇野静夫

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. PICHLMAYR Rudolf

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. RUDOY Pichlmayr

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMAHARA Yasuyuki 蔦原 康行

蔦原 康行 ツタハラ ヤスユキ

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Improvement of perioperative and postoperative management after hepatic resection for HCC by the regulation of hepatic stellate cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ストレス応答蛋白チオレドキシンによる新しい術後肝障害防止対策Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of perioperative management for hepatic resection based on the stellate cell functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肝細胞・肝星細胞の供培養による細胞増殖相互作用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of hepatic micro circulation by hepatic stellate cell-Application of NAC to liver failurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

N-acetylcysteineによる星細胞活性化の制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Strategy for Liver Failure by Regulating Hepatic Microcirculation through Hepatic Stellate Cell ActivatityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Aspect of Strategy for Liver Failure by Regelating Hepatic Stellate Cell ActivationPrincipal Investigator

Principal Investigator

Project Period (FY)

SHIMAHARA Yasuyuki 蔦原康行

蔦原康行ツタハラヤスユキ