SHIMAHARA Yasuyuki 蔦原康行

… Alternative Names

Researcher Number	30196498
Other IDs
External Links
Affiliation (based on the past Project Information) *help	1997 – 2005: 京都大学, 医学研究科, 助教授 1999: 京都大学, 大学院・医学研究科, 助教授 1999: 京都大学, 大学院・医学研究科, 教授 1995 – 1996: 愛媛大学, 医学部, 助教授 1993: 愛媛大学, 医学部, 助教授 1987 – 1993: 京都大学, 医学部, 助手
Review Section/Research Field	Principal Investigator General surgery / Digestive surgery / General surgery / Digestive surgery Except Principal Investigator Digestive surgery / General surgery / Digestive surgery / Human pathology
Keywords	Principal Investigator 星細胞 / ROCK / 肝線維化 / 肝不全 / NAC / 肝微小循環 / 生体顕微鏡 / Rho kinase阻害剤 / 虚血再潅流障害 / hepatic microcirculation … More Except Principal Investigator 血中ケトン体比 / 肝切除 / 肝移植 / 肝切除術 / GSSG / LOH / 肝ミトコンドリア / GSH / エネルギーチャージ / サイトカイン / SIAH1 / 肝不全 / Liver Transplantation / 遺伝子導入 / 動脈血中ケトン体比 / グルタチオン / ケトン体比 / 手術侵襲 / アポトーシス / 肝虚血再灌流障害 / 肝硬変 / Arterial ketone body ratio / Redox理論 / AKBR / Veno-Venous Bypass / 肝細胞癌 / mdm2 / p53 / 肝再生 / reperfusion / TaqMan PCR / PEG10 / 移植肝 / viability / Redox state / pyridine nucleotides / fluorometry / spectro photometry / 肝保存 / グルカゴン / 肝エネルギ-チャ-ジ / 肝ミトコンドリア酸化的リン酸化能 / 閉塞性黄疸 / 成長ホルモン / インスリン / 経門脈投与 / 肝臓 / ミトコンドリア / グラフトのバイアビリティ / AKBR(血中ケトン体比) / Primary Graft Failure / 血中ケトル体比 / 外科的胆汁うっ滞 / 胆汁酸 / 肝機能評価法 / 血中炎症性サイトカイン / 可溶性接着分子 / 接着分子 / 還元型グルタチオン / 酸化型グルタチオン / GHS / 肝虚血 / 再潅流 / 肝組織 / 腎組織 / HVJ-liposome / kupffer cell / TGH-beta / 肝微小循環 / Y-27632 / 生体蛍光顕微鏡 / β-catenin / Apoptosis / tumor suppressor gene / mutation / methylation / haplo-insufficiency / 術後合併症 / 低酸素血症 / 出血 / 酸化還元状態 / アセト酢酸 / 3ヒドロキシ酪酸 / 膜電位 / 冷却潅流法 / 生体肝移植 / 体内肝冷却潅流 / ケトン対比(KBR) / 肝切除率 / Liver resection / Cold perfusion in-situ / Primary Nonfunction Liver / 肝グラフトのViability / 血中ケトン体比(AKBR) / Initial Non-Functioning Liver / Viability of The Liver Graft / Arterial Ketone Body Ratio / 肝臓外科 / 脳死ドナ- / 生物活性 / ex situ / 甲状腺ホルモン / 肝移植術 / 代謝管理 / Redox Theory / Donor Liver Viability / Living Relared Partial Liver Transplantation / Hepatic Surgery / 腸管うっ血 / autocyto protection / 肝エネルギ-代謝 / 肝再潅流 / 肝再灌流 / 腸管阻血 / アミノ酸 / auto cyto protection / Glutathione / intestinal congestion / autocytoprotection / hepatic energy metabolism / hepatic reperfusion / cytokine / 肝冷却潅流 / 自己肝移植 / 肝腫瘍 / VenoーVenous Bypass / 体内肝冷却潅流法 / Hepatic Malignancy / Cold Perfusion Of The Liver In Situ / Autotransplantation After Partial Resection / 拒絶反応 / リンパ球MTT assay / リンパ球MTT活性 / 病理学的検討 / Rejection / Lymphocyte MTT assay / Arterial Ketone Body Ratio (AKBR) / 拡大肝切除 / 分子シャペロン / 熱ショック蛋白 / 虚血再灌流障害 / 虚血耐性 / プレコンディショニング / 温熱療法 / 障害肝 / 虚血再潅流障害 / Extended liver Surgery / Molecular chaperone / Heat shock protein / Ischemia-reperfusion Injury / Ischemic tolerance / Preconditioning / Hyperthermia / Damaged liver / 胆管細胞癌 / 肝炎ビールマ / P53 / マイクロサテライト / 遺伝子不安定性 / 肝細胞 / 遺伝子変異 / マイクロサテライトマーカー / K-ras / トロトラスト / hepatoma / intrahepatic cholangiocarcinoma / Thorotrast / genomic instability / microsatellite / 増殖性胆管炎 / アポプトーシス / 肝機能評価 / hepatic failure / proliferative cholangitis / gene transfer / apoptosis / レプチン / シグナル伝達 / 遺伝子 / 線維化 / 肝虚血耐性 / 伊藤細胞 / ストレス蛋白 / 細胞外マトリックス / 糖代謝 / 性別 / 術前評価 / Liver regeneration / Hepatectomy / Leptin / Liver cirrhosis / Signal pathway / Gene / Fibrosis / Ischemia / ずり応力 / Rac1 / 虚血再灌潅流 / アデノウイルス / 虚血再灌流 / liver regeneration / shear stress / partial hepatectomy / Racl / ischemia / β-カテニン / マイクロアレイ / 再発 / 定量的RT-PCR / Hepatocellular carcinoma / β-atenin / cDNA microarray / Recurrence / Redox 理論 / 術中侵襲スコア / 根治的広範肝切除 / Redox State / score / Bio-Pump / Redox theory / Hepatic surgical score score / Radical extended hepatectomy Less

SIAH1の肝発癌における関与の解明と肝癌遺伝子治療の可能性に関する研究
- Principal Investigator
  
  HASEGAWA Suguru
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Improvement of perioperative and postoperative management after hepatic resection for HCC by the regulation of hepatic stellate cells.Principal Investigator
- Principal Investigator
  
  HATANO Etsuro, 嶌原康行
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
The research to establish the recurrence predicting system for hepatocellular carcinoma patients by use of genome-wide microarray database and to identify therapeutic molecular targets
- Principal Investigator
  
  SATOH Seiji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
ストレス応答蛋白チオレドキシンによる新しい術後肝障害防止対策Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
ROCK/Rhoシグナル伝達系制御による肝虚血再潅流障害抑制の新しい治療戦略
- Principal Investigator
  
  SATOH Seiji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Development of perioperative management for hepatic resection based on the stellate cell functionPrincipal Investigator
- Principal Investigator
  
  SHIMAHARA Yasuyuki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
肝細胞・肝星細胞の供培養による細胞増殖相互作用Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
肝線維化疾患におけるKupffer cell選択的遺伝子治療の試み
- Principal Investigator
  
  山本成尚
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Regulation of hepatic micro circulation by hepatic stellate cell-Application of NAC to liver failurePrincipal Investigator
- Principal Investigator
  
  SHIMAHARA Yasuyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  KYOTO UNIVERSITY
N-acetylcysteineによる星細胞活性化の制御Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Strategy for Liver Failure by Regulating Hepatic Microcirculation through Hepatic Stellate Cell ActivatityPrincipal Investigator
- Principal Investigator
  
  SHIMAHARA Yasuyuki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  KYOTO UNIVERSITY
Role of "shear stress" in initiation of liver regeneration
- Principal Investigator
  
  IIMURO Yuji
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  HYOGO COLLEGE OF MEDICINE
  Kyoto University
Activation of regeneration capacity of the cirrhotic livers based on the molecular and genetic biology
- Principal Investigator
  
  YAMAOKA Yoshio
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  KYOTO UNIVERSITY
Aspect of Strategy for Liver Failure by Regelating Hepatic Stellate Cell ActivationPrincipal Investigator
- Principal Investigator
  
  SHIMAHARA Yasuyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  KYOTO UNIVERSITY
ミオグロビン遺伝子導入による肝癌に対する集学的治療法の開発Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Evaluation of Indication for Liver Transplantation in Primary Liver Cancers : Focused on Analysis of Multicentric Liver Cancers and Relapse of Prediction.
- Principal Investigator
  
  FUKUMOTO Manabu
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Human pathology
- Research Institution
  TOHOKU University
New Strategy for Liver Failure by Regulating Hepatic Extracellular MatrixPrincipal Investigator
- Principal Investigator
  
  SHIMAHARA Yasuyuki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  KYOTO UNIVERSITY
The relationship between hepatic failure following hepatectomy and induction of apoptosis and its therapeutic approach
- Principal Investigator
  
  YAMAMOTO Naritaka
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  KYOTO UNIVERSITY
Moduration of the molecular chaperone activity to increase the safety of extended liver surgery in the damaged liver patients -- challenge by the induction of stress response and heat shock gene transfection --
- Principal Investigator
  
  YAMAOKA Yoshio
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  KYOTO UNIVERSITY
細胞死からみた外科侵襲の新たな定量化法の開発
- Principal Investigator
  
  山本成尚
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Ehime University
還元型・酸化型グルタチオン代謝変動からみた肝虚血・再潅流時の侵襲評価に関する研究
- Principal Investigator
  
  小林展章
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Ehime University
敗血症時の多臓器不全防止に対する新しい治療法-NO吸入療法の確立に関する研究Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Ehime University
炎症反応からみた新しい肝機能評価の確立
- Principal Investigator
  
  山本成尚
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Ehime University
肝臓外科において手術侵襲を軽減する手術手技の開発
- Principal Investigator
  
  山岡義生
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
外科的胆汁うっ滞病変における胆汁酸及びグルタチオン代謝変動の意義に関する研究
- Principal Investigator
  
  KOBAYASHI Nobuaki
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Ehime University
ポータブル血中ケトン体測定器の試作
- Principal Investigator
  
  山岡義生
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
Perioperative management in clinical liver traus plantation
- Principal Investigator
  
  YAMAOKA Yoshio, 小澤和恵
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyoto University Faculty of Medicine, The Secoud Department of Surgery
人工肝補助装置を用いた脳死肝,屍体肝viability向上に対する研究Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
成長ホルモン・経門脈インスリン投与による肝切除術後代謝管理法の開発
- Principal Investigator
  
  森敬一郎
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Surgical Treatment for Hepatic Malignancy, In Situ and Ex Situ
- Principal Investigator
  
  YAMAOKA Yoshio
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  KYOTO UNIVERSITY
UW液を用いた人工肝の効率改善に関する研究Principal Investigator
- Principal Investigator
  
  島原康行
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
肝ミトコンドリア機能よりみたグルカゴン投与による新たな肝予備力評価法の開発
- Principal Investigator
  
  森敬一郎
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Evaluation of liver graft viability in human liver transplantation.
- Principal Investigator
  
  OZAWA Kazue
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyoto University
Use of Redox theory in the perioperative metabolic support and the treatment in liver surgery and transplant.
- Principal Investigator
  
  OZAWA Kazue
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
The investigation on the relation between the glutathione metabolism and liver atrophy.
- Principal Investigator
  
  KOBAYASHI Nobuaki
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Ehime University
  Kyoto University
遠心型ポンプを用いた人工肝の効率改善に関する研究Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
生着率の向上を目的とした移植肝viabilityの非侵襲的判定装置の開発
- Principal Investigator
  
  小澤和恵
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
Hepatic Resection Using in-situ Cold Perfusion Under Total Vascular Exclusion
- Principal Investigator
  
  YAMAOKA Yoshio
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
簡便性と安全性の向上を目的とした生物学的肝補助装置の改良Principal Investigator
- Principal Investigator
  
  嶌原康行
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
肝不全の診断と治療のためのRedox全自動連続分析装置の試作研究
- Principal Investigator
  
  小澤和恵
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
Quantification of operative stress for radical extended hepatectomy
- Principal Investigator
  
  OZAWA Kazue
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  KYOTO UNIVERSITY
外科手術後の多臓器不全における代謝異常と細胞障害の分析
- Principal Investigator
  
  山岡義生
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University

All 2006 2005 2004 2003 2002 2001

All Journal Article

[Journal Article] Prognostic index for patients with hepatocellular carcinoma combined with tumor thrombosis in the major portal vein.2006
- Author(s)
  Ikai I, Hatano E, Hasegawa S, Fujii H, Taura K, Uyama N, Shimahara Y.
- Journal Title
  
  J Am Coll Surg. 202(3)
  
  Pages: 431-438
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] High volume hydrodynamic injection of plasmid DNA via the hepatic artery results in a high level of gene expression in rat hepatocellular carcinoma induced by diethylnitrosamine.2006
- Author(s)
  Tada M, Hatano E, Taura K, Nitta T, Koizumi N, Ikai I, Shimahara Y.
- Journal Title
  
  J Gene Med. 8(8)
  
  Pages: 1018-1026
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Preoperative positron emission tomography with fluorine-18-fluorodeoxyglucose is predictive of prognosis in patients with hepatocellular carcinoma after resection.2006
- Author(s)
  Hatano E, Ikai I, Higashi T, Teramukai S, Torizuka T, Saga T, Fujii H, Shimahara Y.
- Journal Title
  
  World J Surg. 30(9)
  
  Pages: 1735-1741
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Implication of frequent local ablation therapy for intrahepatic recurrence in prolonged survival of patients with hepatocellular carcinoma undergoing hepatic resection : an analysis of 610 patients over 16 years old.2006
- Author(s)
  Taura K, Ikai I, Hatano E, Fujii H, Uyama N, Shimahara Y.
- Journal Title
  
  Ann Surg. 244(2)
  
  Pages: 265-273
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Pancreatic arteriovenous malformation with portal hypertension.2006
- Author(s)
  Hosogi H, Ikai I, Hatano E, Taura K, Fujii H, Yamamoto Y, Shimahara Y.
- Journal Title
  
  J Hepatobiliary Pancreat Surg. 13(4)
  
  Pages: 344-346
- NAID
  10018169412
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Complete response by a combination of 5-fluorouracil and interferon-alpha chemotherapy for lung metastasis of hepatocellular carcinoma after hepatic resection with portal and hepatic vein tumor thrombectomy.2005
- Author(s)
  Hosogi H, Ikai I, Hatano E, Taura K, Fujii H, Yamamoto N, Shimahara Y.
- Journal Title
  
  Hepatol Res. 33(4)
  
  Pages: 320-324
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Blocking of PI3K/Akt pathway enhances apoptosis induced by SN-38, an active form of CPT-11, in human hepatoma cells.2005
- Author(s)
  Koizumi N, Hatano E, Nitta T, Tada M, Harada N, Taura K, Ikai I, Shimahara Y.
- Journal Title
  
  Int J Oncol. 26(5)
  
  Pages: 1301-1306
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Overexpression of thioredoxin prevents thioacetamide-induced hepatic fibrosis in mice.2005
- Author(s)
  Okuyama H, Nakamura H, Shimahara Y, Uyama N, Kwon YW, Kawada N, Yamaoka Y, Yodoi J.
- Journal Title
  
  J Hepatol. 42(1)
  
  Pages: 117-123
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Suppression of VEGFR-3 signaling inhibits lymph node metastasis in gastric cancer.2004
- Author(s)
  Shimizu K, Kubo H, Yamaguchi K, Kawashima K, Ueda Y, Matsuo K, Awane M, Shimahara Y, Takabayashi A, Yamaoka Y, Satoh S.
- Journal Title
  
  Cancer Sci. 95(4)
  
  Pages: 328-333
- NAID
  10013722475
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Effectiveness of endoscopic nasobiliary drainage for postoperative bile leakage after hepatic resection.2004
- Author(s)
  Terajima H, Ikai I, Hatano E, Uesugi T, Yamamoto Y, Shimahara Y, Yamaoka Y.
- Journal Title
  
  World J Surg. 28(8)
  
  Pages: 782-786
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390376
[Journal Article] Overexpression of thioredoxin prevents acute hepatitis caused by thioacetamide or lipopolysaccharide in mice.2003
- Author(s)
  H.Okuyama, H.Nakamura, Y.Shimahara, S.Araya, N.Kawada, Y.Yamaoka, J.Yodoi
- Journal Title
  
  Hepatology 37
  
  Pages: 1015-1025
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370355
[Journal Article] Reduction of hepatic ischemia/reperfusion-induced injury by a specifi ROCK/Rho kinase inhibitor Y-27632.2003
- Author(s)
  F.Ikeda, H.Terajima, Y.Shimahara, T.Kondo, Y.Yamaoka
- Journal Title
  
  J Surg Res 109(2)
  
  Pages: 155-160
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370355
[Journal Article] The hepatic stellate cell in the post-genomic era.2002
- Author(s)
  H.Okuyama, Y.Shimahara, N.Kawada
- Journal Title
  
  Histology and Histopathology 17
  
  Pages: 487-495
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370355
[Journal Article] Significance of serum type IV collagen level of hepatectomized patients with chronic liver damage.2002
- Author(s)
  Y.Shimahara, N.Yamamoto, N.Uyama, H.Okuyama, H.Momoi, T.Kamikawa, H.Terajima, Y.Iimuro, Y.Yamamoto, I.Ikai, F.Kushihata, H.Kiyochi, N.Kobayashi, Y.Yamaoka
- Journal Title
  
  World J Surg 26(4)
  
  Pages: 451-456
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370355
[Journal Article] Regulation of Cultured Rat Hepatocyte Proliferation by Stellate Cells.2002
- Author(s)
  N.Uyama, Y.Shimahara, N.Kawada, S.Seki, H.Okuyama, Y.Iimuro Y.Yamaoka
- Journal Title
  
  J Hepatol 36
  
  Pages: 590-599
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370355
[Journal Article] Significance of serum type IV collagen level of hepatectomized patients with chronic liver damage.2002
- Author(s)
  Shimahara Y
- Journal Title
  
  World-J-Surg. 26(4)
  
  Pages: 451-456
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557100
[Journal Article] Regulation of Cultured Rat Hepatocyte Proliferation by Stellate Cells.2002
- Author(s)
  Uyama-N., Shimahara-Y., Kawada-N., Seki-S., Okuyama-H., Iimuro-Y., Yamaoka-Y.
- Journal Title
  
  Journal of Hepatology 36
  
  Pages: 590-599
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557100
[Journal Article] Significance of serum type IV collagen level of hepatectomized patients with chronic liver damage.2002
- Author(s)
  Y.Shimahara
- Journal Title
  
  World J Surg 26
  
  Pages: 451-456
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370355
[Journal Article] Significance of serum type IV collagen level of hepatectomized patients with chronic liver damage.2002
- Author(s)
  Shimahara-Y., Yamamoto-N., Uyama-N., et al.
- Journal Title
  
  World J Surg 26(4)
  
  Pages: 451-456
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557100
[Journal Article] The interaction between hepatocytes and stellate cells on individual cell proliferation and differentiation2001
- Author(s)
  Uyama-N., Kawada-N., Ikuyama-H., Iimuro-Y., Kaneda-K., Shimahara-Y., Yamaoka-Y.
- Journal Title
  
  Cells of Hepatic Sinusoid 8
  
  Pages: 51-54
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557100
[Journal Article] Regulation of cell growth by redox-mediated extracellular proteolysis of platelet-derived growth factor receptor beta.2001
- Author(s)
  Okuyama, -H., Shimahara, -Y., Kawada, -N., Seki, -S., Kristensen, -D.-B., Yoshizato, -K., Uyama, -N., Yamaoka,-Y.
- Journal Title
  
  J-Biol-Chem. 276(30)
  
  Pages: 28274-28280
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557100

1. YAMAOKA Yoshio (90089102)

# of Collaborated Projects: 27 results

# of Collaborated Products: 7 results
2. OZAWA Kazue (00026858)

# of Collaborated Projects: 14 results

# of Collaborated Products: 0 results
3. YAMAMOTO Maritaka (30253298)

# of Collaborated Projects: 14 results

# of Collaborated Products: 2 results
4. MORI Keiichiro (80159186)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
5. KAWADA Norihumi (30271191)

# of Collaborated Projects: 9 results

# of Collaborated Products: 7 results
6. KOBAYASHI Nobuaki (60135564)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
7. IIMURO Yuji (30252018)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
8. YAMAMOTO Yuzo (70281730)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
9. TANAKA Kouichi (20115877)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
10. MORIMOTO Taisuke (60135910)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
11. TANAKA Akira (00240820)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
12. IKAI Iwao (60263084)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
13. HONDA Kazuo (00209321)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
14. NAKAMURA Hajime (70303914)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
15. SATOH Seiji (00303834)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
16. HATANO Etsuro (80359801)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
17. TERAJIMA Hiroaki (40314215)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
18. HASEGAWA Suguru (10362500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. ピッケルマイヤールドル

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. ルドルフピッケルマイヤ

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. KINOSHITA Seiichi (10169906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. YAMABE Hirohiko (00135592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. INAMOTO Takashi (10135577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. FUKUMOTO Manabu (60156809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SATOMI Susumu (00154120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. MANABE Noboru (80243070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. YAEGASHI Hiroshi (40182290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. FUJIMOTO Jiro (90199373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. UYAMA Naoki (70402873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
30. KISHIMOTO Michimasa (00144436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. FUKUSHIMA Masanori (80107820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 折井豊 (60028149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 岩川和秀 (30243786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 松田良一 (10243784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 柴田徹 (40293857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 山内清明 (00291427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 尾崎信弘 (50211818)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 松井茂之 (80305854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 長村俊彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 森尚樹

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 青木吉平

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 宇野静夫

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. PICHLMAYR Rudolf

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. RUDOY Pichlmayr

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMAHARA Yasuyuki 蔦原 康行

蔦原 康行 ツタハラ ヤスユキ

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Improvement of perioperative and postoperative management after hepatic resection for HCC by the regulation of hepatic stellate cells.Principal Investigator

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ストレス応答蛋白チオレドキシンによる新しい術後肝障害防止対策Principal Investigator

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Development of perioperative management for hepatic resection based on the stellate cell functionPrincipal Investigator

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肝細胞・肝星細胞の供培養による細胞増殖相互作用Principal Investigator

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Regulation of hepatic micro circulation by hepatic stellate cell-Application of NAC to liver failurePrincipal Investigator

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N-acetylcysteineによる星細胞活性化の制御Principal Investigator

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Strategy for Liver Failure by Regulating Hepatic Microcirculation through Hepatic Stellate Cell ActivatityPrincipal Investigator

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Aspect of Strategy for Liver Failure by Regelating Hepatic Stellate Cell ActivationPrincipal Investigator

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SHIMAHARA Yasuyuki 蔦原康行

蔦原康行ツタハラヤスユキ