YAMAKAWA DAISHI 山川大史

… Alternative Names

Yamakawa Daishi 山川大史

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Researcher Number	20631097
Other IDs
Affiliation (Current)	2025: 三重大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2017 – 2023: 三重大学, 医学系研究科, 助教 2015: 大阪大学, 微生物病研究所, 研究員 2014 – 2015: 大阪大学, 微生物病研究所, 特任研究員(常勤)
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related / Pathological medical chemistry / Tumor biology Except Principal Investigator Basic Section 49010:Pathological biochemistry-related / Basic Section 48030:Pharmacology-related
Keywords	Principal Investigator デスミン / 筋再生 / 骨格筋 / 心筋 / 筋肉 / 中間径フィラメント / 分化 / 間葉系前駆細胞 / 脂肪前駆細胞 / 脂肪細胞 … More / 一次線毛 / ビメンチン / 骨格筋障害 / 筋 / リン酸化 / 循環器 / 発生学 / 生理学 / 分子病態学 / 平滑筋 / 早老症 / 老化 / 細胞分裂 / Desmin / 抗腫瘍効果 / Tie2 / Tie1 / 血管内皮細胞 / 蛋白質分解酵素 / 血管新生阻害 / 腫瘍血管新生 … More Except Principal Investigator 一次線毛 / 細胞分化 / 細胞増殖 / ユビキチン / 間葉系前駆細胞 / 骨格筋 / 骨格筋再生 / 再生 / 細胞増殖受容体 / カベオラ / 脂質ラフト / 脂肪前駆細胞 / p27Kip1 / p27Ki1 / 中心体 / インターロイキン１３ / シグナル伝達 / 肥満 Less

Understanding for the mechanism regulating adipocyte differentiation by primary cilia elongationPrincipal Investigator
- Principal Investigator
  
  山川大史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Mie University
Elucidation of the mechanism of muscle regeneration regulated by primary cilia of mesenchymal progenitors
- Principal Investigator
  
  西村有平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Mie University
Primary cilia-mediated signaling for cell growth and differentiation
- Principal Investigator
  
  Inagaki Masaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Mie University
Regulation of primary cilia formation by the ubiquitinーproteasome system
- Principal Investigator
  
  Kasahara Kousuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Mie University
Elucidation of the physiological and pathological significance of desmin phosphorylation in muscle damage and repairPrincipal Investigator
- Principal Investigator
  
  Yamakawa Daishi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Mie University
Histological and functional analysis of phosphodesmin-deficient micePrincipal Investigator
- Principal Investigator
  
  Yamakawa Daishi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Mie University
Analysis of regulatory mechanism of tumor angiogenesis by Tie1 ectodomainPrincipal Investigator
- Principal Investigator
  
  YAMAKAWA DAISHI
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Osaka University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Patent

[Journal Article] Cilia‐Mediated Insulin/Akt and ST2/JNK Signaling Pathways Regulate the Recovery of Muscle Injury2022
- Author(s)
  Yamakawa Daishi、Tsuboi Junya、Kasahara Kousuke、Matsuda Chise、Nishimura Yuhei、Kodama Tatsuya、Katayama Naoyuki、Watanabe Masatoshi、Inagaki Masaki
- Journal Title
  
  Advanced Science
  
  Volume: 10 Issue: 1 Pages: 2202632-2202632
- DOI
  10.1002/advs.202202632
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09499, KAKENHI-PROJECT-20H03448, KAKENHI-PROJECT-21H02696
[Journal Article] Aurora A and AKT Kinase Signaling Associated with Primary Cilia2021
- Author(s)
  Nishimura Yuhei、Yamakawa Daishi、Shiromizu Takashi、Inagaki Masaki
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 12 Pages: 3602-3602
- DOI
  10.3390/cells10123602
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07318, KAKENHI-PROJECT-20K07356, KAKENHI-PROJECT-21H02696
[Journal Article] Primary cilia and lipid raft dynamics2021
- Author(s)
  Nishimura Yuhei、Yamakawa Daishi、Uchida Katsunori、Shiromizu Takashi、Watanabe Masatoshi、Inagaki Masaki
- Journal Title
  
  Open Biology
  
  Volume: 11 Issue: 8 Pages: 210130-210130
- DOI
  10.1098/rsob.210130
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07318, KAKENHI-PROJECT-19K09708, KAKENHI-PROJECT-19H04205, KAKENHI-PROJECT-20K07356, KAKENHI-PROJECT-20K07371, KAKENHI-PROJECT-21H02696
[Journal Article] Primary cilia-dependent lipid raft/caveolin dynamics regulate adipogenesis2021
- Author(s)
  Yamakawa Daishi、Katoh Daisuke、Kasahara Kousuke、Shiromizu Takashi、Matsuyama Makoto、Matsuda Chise、Maeno Yumi、Watanabe Masatoshi、Nishimura Yuhei、Inagaki Masaki
- Journal Title
  
  Cell Reports
  
  Volume: 34 Issue: 10 Pages: 108817-108817
- DOI
  10.1016/j.celrep.2021.108817
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07318, KAKENHI-PROJECT-18K06890, KAKENHI-PROJECT-19K09708, KAKENHI-PROJECT-19H04205, KAKENHI-PROJECT-20H03448, KAKENHI-PROJECT-20K07356
[Journal Article] Indispensable role of Galectin-3 in promoting quiescence of hematopoietic stem cells2021
- Author(s)
  Jia Weizhen、Kong Lingyu、Kidoya Hiroyasu、Naito Hisamichi、Muramatsu Fumitaka、Hayashi Yumiko、Hsieh Han-Yun、Yamakawa Daishi、Hsu Daniel K.、Liu Fu-Tong、Takakura Nobuyuki
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 2118-2118
- DOI
  10.1038/s41467-021-22346-2
- NAID
  120007096897
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16742, KAKENHI-PROJECT-20K07356, KAKENHI-PROJECT-19K16741, KAKENHI-PROJECT-21K15531
[Journal Article] Targeting E3 Ubiquitin Ligases and Deubiquitinases in Ciliopathy and Cancer2020
- Author(s)
  Shiromizu Takashi、Yuge Mizuki、Kasahara Kousuke、Yamakawa Daishi、Matsui Takaaki、Bessho Yasumasa、Inagaki Masaki、Nishimura Yuhei
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 17 Pages: 5962-5962
- DOI
  10.3390/ijms21175962
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07318, KAKENHI-PROJECT-19K22433, KAKENHI-PROJECT-20H03448, KAKENHI-PROJECT-18K06890, KAKENHI-PROJECT-20K07356
[Journal Article] Regulation of keratin 5/14 intermediate filaments by CDK1, Aurora-B, and Rho-kinase2018
- Author(s)
  Inaba H, Yamakawa D, Tomono Y, Enomoto A, Mii S, Kasahara K, Goto H, Inagaki M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 498 Issue: 3 Pages: 544-550
- DOI
  10.1016/j.bbrc.2018.03.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08269, KAKENHI-PROJECT-17K15615, KAKENHI-PLANNED-24113005, KAKENHI-PROJECT-15H02398, KAKENHI-PROJECT-15K08324, KAKENHI-PROJECT-16K19104, KAKENHI-PROJECT-18K06927, KAKENHI-PROJECT-18K15002
[Journal Article] Visualization of Proliferative Vascular Endothelial Cells in Tumors in?Vivo by Imaging Their Partner of Sld5-1 Promoter Activity2018
- Author(s)
  Yamakawa Daishi、Jia Weizhen、Kidoya Hiroyasu、Hosojima Shoko、Torigata Miku、Zhang Li、Takakura Nobuyuki
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 188 Issue: 5 Pages: 1300-1314
- DOI
  10.1016/j.ajpath.2018.01.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02470, KAKENHI-PROJECT-17K15615, KAKENHI-PROJECT-16H06147
[Journal Article] Apelin as a marker for monitoring the tumor vessel normalization window during antiangiogenic therapy.2016
- Author(s)
  Zhang L, Takara K, Yamakawa D, Kidoya H, Takakura N.
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Issue: 1 Pages: 36-44
- DOI
  10.1111/cas.12836
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26830072, KAKENHI-PROJECT-24300330, KAKENHI-PROJECT-15K14380, KAKENHI-PROJECT-16H06147
[Journal Article] APJ Regulates Parallel Alignment of Arteries and Veins in the Skin.2015
- Author(s)
  Kidoya H, Naito H, Muramatsu F, Yamakawa D, Jia W, Ikawa M, Sonobe T, Tsuchimochi H, Shirai M, Adams RH, Fukamizu A, Takakura N.
- Journal Title
  
  Dev Cell.
  
  Volume: 33 Issue: 3 Pages: 247-259
- DOI
  10.1016/j.devcel.2015.02.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14380, KAKENHI-PROJECT-15K18409, KAKENHI-INTERNATIONAL-15K21737, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-26670413, KAKENHI-PROJECT-26830072, KAKENHI-PROJECT-24300330
[Patent] 筋損傷時の筋再生を促進するための治療用インターロイキン13（IL-13）2022
- Inventor(s)
  稲垣昌樹、山川大史、西村有平
- Industrial Property Rights Holder
  稲垣昌樹、山川大史、西村有平
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-097615
- Filing Date
  2022
- Acquisition Date
  2022
- Data Source
  KAKENHI-PROJECT-21H02696
[Presentation] Primary cilia regulate the recovery of muscle injury through insulin/Akt and ST2/JNK signaling pathways2023
- Author(s)
  Yamakawa D, Tsuboi J, Kasahara K, Matsuda C, Nishimura Y, Kodama T, Katayama N, Watanabe M, Inagaki M.
- Organizer
  Cold Spring Harbor Asia Conference Cilia & Centrosomes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02696
[Presentation] ゼブラフィッシュヒレ再生における一次線毛の役割2022
- Author(s)
  白水崇、山川大史、稲垣昌樹、西村有平
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02696
[Presentation] 組織修復における一次繊毛制御因子トリコプレインの新たな役割2022
- Author(s)
  西村有平、山川大史、白水崇、渡邉昌俊、稲垣昌樹
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02696
[Presentation] An investigation of the role of primary cilia in the repairing process after brain injury2022
- Author(s)
  Takashi Shiromizu, Ryohei Shibata, Daishi Yamakawa, Masaki Inagaki and Yuhei Nishimura
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02696
[Presentation] 一次線毛は脂質ラフトの動態制御を介して脂肪細胞分化に関与する2022
- Author(s)
  西村有平、山川大史、白水崇、稲垣昌樹
- Organizer
  第51回日本心脈管作動物質学会
- Data Source
  KAKENHI-PROJECT-21H02696
[Presentation] 一次繊毛による細胞増殖・分化制御と疾患2021
- Author(s)
  笠原広介, 山川大史, 稲垣昌樹
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03448
[Presentation] Suppression of obesity and hepatic steatosis by modulating ciliogenesis2021
- Author(s)
  Daishi Yamakawa, Kousuke Kasahara, Masatoshi Watanabe, Masaki Inagaki
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02696
[Presentation] Primary cilia regulate adipogenesis through lipid raft dynamics2021
- Author(s)
  Yuhei Nishimura, Daishi Yamakawa, Daisuke Katoh, Kousuke Kasahara, Takashi Shiromizu, Makoto Matsuyama, Chise Matsuda, Yumi Maeno, Masatoshi Watanabe, and Masaki Inagaki
- Organizer
  The 23rd Korea-Japan Joint Seminar on Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02696
[Presentation] 一次線毛形成制御による肥満・脂肪肝の抑制2021
- Author(s)
  山川大史、笠原広介、渡邉昌俊、稲垣昌樹
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07356
[Presentation] ユビキチン修飾系による一次線毛動態制御と疾患治療2021
- Author(s)
  笠原広介、山川大史、稲垣昌樹
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02696
[Presentation] ユビキチン修飾系による一次線毛動態制御と疾患治療2021
- Author(s)
  笠原広介、山川大史、稲垣昌樹
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07356
[Presentation] 一次繊毛による細胞増殖・分化制御と疾患2021
- Author(s)
  笠原広介、山川大史、稲垣昌樹
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02696
[Presentation] ユビキチン修飾系による一次線毛動態制御と疾患治療2021
- Author(s)
  笠原広介, 山川大史、稲垣昌樹
- Organizer
  第25回日本がん分子標的治療学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03448
[Presentation] 一次線毛を介した脂肪細胞分化制御2020
- Author(s)
  西村有平、山川大史、白水崇、稲垣昌樹
- Organizer
  第４９回日本心脈管作動物質学会年会
- Data Source
  KAKENHI-PROJECT-17K15615
[Presentation] 一次線毛と細胞増殖・分化・がん化2020
- Author(s)
  稲垣昌樹、笠原広介、山川大史、松田知世、渡邉昌俊
- Organizer
  第７９回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07356
[Presentation] 一次線毛と細胞増殖・分化・がん化2020
- Author(s)
  稲垣昌樹、笠原広介, 山川大史、松田知世、渡邉昌俊
- Organizer
  第79回日本癌学会学術総会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03448
[Presentation] 一次線毛と細胞増殖・分化～発がん研究の新しい視点～2019
- Author(s)
  稲垣昌樹、山川大史、笠原広介、加藤大祐、渡邉昌俊
- Organizer
  第３４回発癌病理研究会
- Data Source
  KAKENHI-PROJECT-17K15615
[Presentation] The keratin filament-binding protein Trichoplein regulates production of intradermal adipocytes2018
- Author(s)
  Daishi Yamakawa, Kousuke Kasahara, Masaki Ingaki
- Organizer
  Gordon Research Conference Intermediate Filaments
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15615
[Presentation] The primary cilia-related trichoplein regulates proliferation and differentiation of mesenchymal stem cells2018
- Author(s)
  Daishi Yamakawa, Kousuke Kasahara, Makoto Matsuyama, Masaki Ingaki
- Organizer
  第４１回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K15615
[Presentation] CDK1によるケラチン5のリン酸化が皮膚基底層上皮細胞の細胞分裂に必要である2017
- Author(s)
  山川大史、稲葉弘哲、笠原広介、榎本篤、友野靖子、後藤英仁、稲垣昌樹
- Organizer
  第69回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-17K15615
[Presentation] EGF receptor kinase suppresses ciliogenesis by activating Usp8 deubiquitinase2017
- Author(s)
  Kousuke Kasahara, Hiromasa Aoki, Tohru Kiyono, Daishi Yamakawa, Naoki Goshima, Masaki Inagaki
- Organizer
  第69回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-17K15615
[Presentation] 腫瘍血管新生におけるTie1細胞外ドメイン切断の意義2016
- Author(s)
  山川大史
- Organizer
  第2回血管生物医学会若手研究会
- Place of Presentation
  仙台
- Year and Date
  2016-03-04
- Data Source
  KAKENHI-PROJECT-26830072
[Presentation] Tie1細胞外ドメインの脱落が腫瘍血管新生を制御する2015
- Author(s)
  山川大史、木戸屋浩康、ジャイシン、橘田未来、高倉伸幸
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-26830072
[Presentation] DNA複製因子PSF1のプロモーター活性を指標とした増殖血管内皮細胞の分離2015
- Author(s)
  山川大史、木戸屋浩康、橘田未来、細島祥子、高倉伸幸
- Organizer
  第23回日本血管生物医学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-26830072

1. Kasahara Kousuke (90455535)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. Inagaki Masaki (30183007)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
3. 白水崇 (00582678)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 西村有平 (30303720)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. KIDOYA Hiroyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. MURAMATSU Fumitaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 松田知世

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 渡辺昌俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 高倉伸幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAMAKAWA DAISHI 山川 大史

Yamakawa Daishi 山川 大史

Research Projects

Research Products

Co-Researchers

Understanding for the mechanism regulating adipocyte differentiation by primary cilia elongationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of muscle regeneration regulated by primary cilia of mesenchymal progenitors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Primary cilia-mediated signaling for cell growth and differentiation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of primary cilia formation by the ubiquitinーproteasome system

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the physiological and pathological significance of desmin phosphorylation in muscle damage and repairPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Histological and functional analysis of phosphodesmin-deficient micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of regulatory mechanism of tumor angiogenesis by Tie1 ectodomainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cilia‐Mediated Insulin/Akt and ST2/JNK Signaling Pathways Regulate the Recovery of Muscle Injury2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aurora A and AKT Kinase Signaling Associated with Primary Cilia2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Primary cilia and lipid raft dynamics2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Primary cilia-dependent lipid raft/caveolin dynamics regulate adipogenesis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Indispensable role of Galectin-3 in promoting quiescence of hematopoietic stem cells2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Targeting E3 Ubiquitin Ligases and Deubiquitinases in Ciliopathy and Cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of keratin 5/14 intermediate filaments by CDK1, Aurora-B, and Rho-kinase2018

Author(s)

YAMAKAWA DAISHI 山川大史

Yamakawa Daishi 山川大史