NISHIMURA Yuuhei 西村有平

… Alternative Names

Researcher Number	30303720
Other IDs	https://orcid.org/0000-0003-1901-8799
External Links
Affiliation (Current)	2019 : 三重大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2019 : 三重大学, 医学系研究科, 教授 2015 : 三重大学, 大学院医学系研究科, 准教授 2014 – 2015 : 三重大学, 医学(系)研究科(研究院), 准教授 2014 : 三重大学, 大学院医学系研究科・薬理ゲノミクス, 准教授 2011 – 2013 : 三重大学, 医学(系)研究科(研究院), 講師 … More
Review Section/Research Field	Principal Investigator General pharmacology / Risk sciences of radiation/Chemicals / Basic Section 48030:Pharmacology-related Except Principal Investigator 応用薬理学・医療系薬学 / General pharmacology / Biological Sciences / General pharmacology / Basic Section 48030:Pharmacology-related / Pediatrics
Keywords	Principal Investigator ゼブラフィッシュ / 行動解析 / スクリーニング / 心血管・血液 / オミックス解析 / 一時線毛 / 蛍光生体イメージング / ユビキチン・プロテアソーム系 / 遺伝子発現 / アンジオテンシン … More Except Principal Investigator S100C / 脳血管攣縮 / カルシウム / 遺伝子発現 / カルシウム結合蛋白質 / トランスクリプトーム / EFハンド / actin / S100ファミリー / アクチン / DNAマイクロアレイ / トランスクリプトーム解析 / 脳血管障害 / 低酸素 / ゼブラフィッシュ / gene expression / Heme Oxygenase-1 / in situ hybridization / 病態 / 平滑筋 / S100L / HSP72 / cerebral vasospasm / caltractin / mRNA differential display / 薬物治療学 / 薬理ゲノミクス / splicing / 蛍光試薬 / ゲノム創薬 / 血管平滑筋 / プロテインキナーゼ / smooth muscle / stress protein / マルチメディアデータベース / 肥満 / in silico cDNAクローニング / antisense oligodeoxynucleotide / antiallergic drugs / アクチン結合タンパク質 / 低酵素 / 好酸球走化性 / 分子薬理学 / アクチン活性化ミオシンATPase / くも膜下出血 / カルポニン / オミックス / hypoxia / Actin Binding Proteins / Differential Gene Expression / proteome database / Actin activated Mg myosin ATPase activity / 情報伝達 / Mg2+-ATPase / immunological tolerance / two-hybrid system / キャピラリー電気泳動 / 螢光ディファレンシャル・ディスプレイ法 / 甲状腺疾患 / 治療関連遺伝子 / 悪性腫瘍免疫寛容 / プロテオーム / 免疫寛容関連遺伝子 / 血管収縮 / Pharmacogenomics / pulmonary hypertension / アクチン結合部位 / がん幹細胞選択性 / 動物モデル / スプライシング / cance / カルシウム感受性 / Protein kinase / 病態遺伝子 / 創薬・ゲノム薬理学 / DNAチップ / システムズ薬理学 / Mg-ATPase活性 / 一次線毛 / 肺高血圧症 / ヒトがん幹細胞治療薬 / マイクロアレイ法 / 治療遺伝子 / calponin / ヒト慢性骨髄性白血病細胞 / Disease / Gene Expression / 悪性腫瘍治療抵抗性 / ラット / heat shock protein 72 / S100 Protein Family / クローニング / 種々の病態 / Chemotactic proteins / ゲノム創薬科学 / 好酸球定化性 / 異種細胞免疫寛容機構 / xenotransplantation / 免疫機構 / ストレス蛋白質 / カルシウム結合蛋白 / タウリン / 脳虚血 / 異遺伝子発現 / phosphodiesterase / ヘムオキシゲナーゼ / RNA-seq / セリン・スレオニンキナーゼ / ハイポキシアレスポンスエレメント / 薬理ゲノム科学 / バセドウ病 / vascular remodeling / ヒトがん幹細胞阻害薬 / チロシンキナーゼ / 遺伝子治療 / プロテオームデータベース / ZM-B708 / 蛋白質リン酸化酵素 / 脂質異常症 / 走化性蛋白質 / クモ膜下出血 / 治療 / 疾患関連遺伝子 / ヒト前立腺癌細胞 / 肺動脈性肺高血圧 / Mg-ATPase / Eosinophils / CO / Calcium-binding Proteins / Signal transduction / Calcium / マイクロアレイ / human clinical pathology / PDE / thyroid disease / 薬物治療遺伝子 / 悪性腫瘍 / ディファレンシャル・ディスプレイ法 / 創薬ターゲット / 肥満モデル / calcium / Actin / basilar artery / 癌 / gene therapy / rat / S100 family / Zebrafish / Basedow's disease / エンドセリン / 肺高血圧 / 好酸球 / breast carcinoma / ESTデータベース / cGMP / 収縮制御 / アクチン活性化MgミオシンATPase活性 / calcium sensitization / 遺伝子 / 免疫不全マウス / Actin binding gites / 遺伝子クラスター / ヒト疾患病態 / プロテインキナーゼ阻害薬 / 乳癌 / 疾患モデル / heat shock protein 27 / バイオインフォマティクス / 脳底動脈 / 抗アレルギー薬 / proteome / 炎症 / 血管リモデリング / 血管生物学 / hemin Less

複合的アプローチを用いた多発性嚢胞腎の新規病態メカニズム解明Principal InvestigatorOngoing
- Principal Investigator
  
  西村有平
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Mie University
一次線毛の動態制御によるがん治療法開発を志向したマルチオミックス解析Ongoing
- Principal Investigator
  
  白水崇
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Mie University
新しい肥大型心筋症病態遺伝子のシステムズ薬理学Principal InvestigatorOngoing
- Principal Investigator
  
  西村有平
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Mie University
New treatment for pulmonary arterial hypertension targeting on inflammation-dedifferentiation pathway
- Principal Investigator
  
  Mitani Yoshihide
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Mie University
in vivo Mechanisms of Novel Selective Fluorescent Leukemia Stem Cell Inhibitor
- Principal Investigator
  
  Tanaka Toshio
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Mie University
Novel immunological tolerance in zebrafish of human cancer cell xenotransplants and cancer immunotherapy mechanisms
- Principal Investigator
  
  TANAKA TOSHIO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Mie University
Development of zebrafish-based assay to detect developmental neurotoxicity of irradiation and to identify protectants against the neurotoxicityPrincipal Investigator
- Principal Investigator
  
  NISHIMURA Yuhei
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Mie University
エリオシトリンによるメタボリックシンドローム改善作用の網羅的メカニズム解析
- Principal Investigator
  
  島田康人
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Mie University
Identification of novel drug targets with Omics-based mechanismsfor obesity treatment
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Mie University
脳血管障害におけるゲノム創薬ターゲットの作用機構解析
- Principal Investigator
  
  田中利男
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Mie University
遺伝子発現プロファイルに基づく降圧薬のクラスタリングPrincipal Investigator
- Principal Investigator
  
  西村有平
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Mie University
脳血管障害におけるゲノム創薬ターゲット探索法の開発
- Principal Investigator
  
  田中利男
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Mie University
トランスクリプトーム解析とファルマインフォマティクスの統合ゲノム薬理学
- Principal Investigator
  
  田中利男
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
Pharmacoproteomic mechanisms in stress protein expression induction
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  Mie University
脳血管障害におけるゲノム創薬科学解析法の開発
- Principal Investigator
  
  田中利男
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Mie University
脳血管攣縮における一酸化炭素(CO)/cGMPシグナリングの治療的役割
- Principal Investigator
  
  田中利男
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
Pharmacogenomics of thyroid disease in molecular target discovery
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
トランスクリプトーム解析によるゲノム創薬科学
- Principal Investigator
  
  田中利男
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Mie University
Molecular cell pharmacology of novel smooth muscle regulation molecule
- Principal Investigator
  
  NAKA Michiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
シグナル伝達の細胞内局在に関する薬理ゲノム科学的解析
- Principal Investigator
  
  田中利男
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
プロテインキナーゼ阻害薬による遺伝子発現制御機構
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Mie University
新しいカルシウムシグナリングの分子機構に関する薬理学的研究
- Principal Investigator
  
  田中利男
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Mie University
Genome pharmacology on novel calcium signaling in diseases
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
Clinical Therapeutic Research of Calcium Sensitization
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
Molecular cell pharmacology of gene expression in eosinophils by antiallergic drugs diseases
- Principal Investigator
  
  NAKA Michiko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
Novel Molecular Pharmacological Strategy in Clinical Therapeutic Research
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University

All 2018 2017 2016 2015 2014 2013 2012 2011 2004 2002 Other

All Journal Article Presentation Book

[Book] Cancer Cell Signaling Methods and Protocols2014
- Author(s)
  Yasuhito Shimada, Yuhei Nishimura, and Toshio Tanaka
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25670127
[Journal Article] EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase2018
- Author(s)
  Kousuke Kasahara, Hiromasa Aoki, Tohru Kiyono, Shujie Wang, Harumi Kagiwada, Mizuki Yuge, Toshio Tanaka, Yuhei Nishimura, Akira Mizoguchi, Naoki Goshima, Masaki Inagaki
- Journal Title
  
  Nat Commun
  
  Volume : 9 Pages : 758-758
- DOI
  10.1038/s41467-018-03117-y
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08547, KAKENHI-PROJECT-17K08269, KAKENHI-PLANNED-24113005, KAKENHI-PROJECT-15H02398
[Journal Article] Overcoming Obstacles to Drug Repositioning in Japan2017
- Author(s)
  Yuhei Nishimura, Masaaki Tagawa, Hideki Ito, Kazuhiro Tsuruma, Hideaki Hara
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume : 11 Pages : 729-729
- DOI
  10.3389/fphar.2017.00729
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08547
[Journal Article] New photic stimulating system with white light-emitting diodes to elicit electroretinograms from zebrafish larvae2017
- Author(s)
  Hisashi Matsubara, Yoshitsugu Matsui, Ryohei Miyata, Yuhei Nishimura, Tetsuro Yamamoto, Toshio Tanaka, Mineo Kondo
- Journal Title
  
  Documenta Ophthalmologica
  
  Volume : 135 Pages : 147-154
- DOI
  10.1007/s10633-017-9602-1
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08547
[Journal Article] Chemokines protect vascular smooth muscle cells from cell death induced by cyclic2017
- Author(s)
  Jing Zhao, Yuhei Nishimura, Akihiko Kimura, Kentaro Ozawa, Toshikazu Kondo, Toshio Tanaka, Masanori Yoshizumi
- Journal Title
  
  Scientific Reports
  
  Volume : 7 Pages : 16128-16128
- DOI
  10.1038/s41598-017-15867-8
- Open Access / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08547, KAKENHI-PROJECT-26293163, KAKENHI-PROJECT-26461277
[Journal Article] DNA Damage Response Is Involved in the Developmental Toxicity of Mebendazole in Zebrafish Retina2016
- Author(s)
  Shota Sasagawa, Yuhei Nishimura, Tetsuo Kon, Yukiko Yamanaka, Soichiro Murakami, Yoshifumi Ashikawa, Mizuki Yuge, Shiko Okabe, Koki Kawaguchi, Reiko Kawase and Toshio Tanaka
- Journal Title
  
  Front. Pharmacol.
  
  Volume : 7
- DOI
  10.3389/fphar.2016.00057
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15051
[Journal Article] Novel immunologic tolerance of human cancer cell xenotransplants in zebrafish.2016
- Author(s)
  Zhang B, Shimada Y, Hirota T, Ariyoshi M, Kuroyanagi J, Nishimura Y, Tanaka T.
- Journal Title
  
  Transl Res.
  
  Volume : 170 Pages : 89-98
- DOI
  10.1016/j.trsl.2015.12.007
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15051
[Journal Article] In Vivo Detection of Mitochondrial Dysfunction Induced by Clinical Drugs and Disease-Associated Genes Using a Novel Dye ZMJ214 in Zebrafish.2016
- Author(s)
  Sasagawa S, Nishimura Y, Koiwa J, Nomoto T, Shintou T, Murakami S, Yuge M, Kawaguchi K, Kawase R, Miyazaki T, Tanaka T.
- Journal Title
  
  ACS Chem Biol.
  
  Volume : 11 Pages : 381-388
- DOI
  10.1021/acschembio.5b00751
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15051
[Journal Article] Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs2016
- Author(s)
  Atsuto Inoue, Yuhei Nishimura, Norihito Matsumoto, Noriko Umemoto , Yasuhito Shimada, Toru Maruyama, Kana Kayasuga, Motohiko Morihara, Jun Katagi, Tsutomu Shiroya, Yasushi Hirota, Soonih Kim , Toshio Tanaka
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume : 3 Pages : 79-87
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15051
[Journal Article] Downregulation of GSTK1 Is a Common Mechanism Underlying Hypertrophic Cardiomyopathy2016
- Author(s)
  Shota Sasagawa, Yuhei Nishimura, Shiko Okabe, Soichiro Murakami, Yoshifumi Ashikawa, Mizuki Yuge, Koki Kawaguchi, Reiko Kawase, Ryuji Okamoto, Masaaki Ito and Toshio Tanaka
- Journal Title
  
  Frontiers in pharmacology
  
  Volume : 7 Pages : 162-162
- DOI
  10.3389/fphar.2016.00162
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08547
[Journal Article] Using zebrafish in systems toxicology for developmental toxicity testing2016
- Author(s)
  Nishimura Y, Inoue A, Sasagawa S, Koiwa J, Kawaguchi K, Kawase R, Maruyama T, Kim S, Tanaka T.
- Journal Title
  
  Congenital Anomalies
  
  Volume : 56 Issue : 1 Pages : 18-27
- DOI
  10.1111/cga.12142
- ISSN
  0914-3505
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15051
[Journal Article] In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5(3)2015
- Author(s)
  Beibei Zhang, Yasuhito Shimada, Junya Kuroyanagi, Michiko Ariyoshi, Tsuyoshi Nomoto, Taichi Shintou, Noriko Umemoto,Yuhei Nishimura, Takeshi Miyazaki, Toshio Tanaka
- Journal Title
  
  Biomaterials
  
  Volume : 52 Pages : 14-25
- DOI
  10.1016/j.biomaterials.2015.02.009
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670127
[Journal Article] Pharmacological profiling of zebrafish behavior using chemical and genetic classification of sleep-wake modifiers2015
- Author(s)
  Nishimura Y, Okabe S, Sasagawa S, Murakami S, Ashikawa Y, Yuge M, Kawaguchi K, Kawase R,Tanaka T.
- Journal Title
  
  Front Pharmacol.
  
  Volume : 6
- DOI
  10.3389/fphar.2015.00257
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15051
[Journal Article] Systems pharmacology of adiposity reveals inhibition of EP300 as a common therapeutic mechanism of caloric restriction and resveratrol for obesity.2015
- Author(s)
  Nishimura Y, Sasagawa S, Ariyoshi M, Ichikawa S, Shimada Y, Kawaguchi K, Kawase R, Yamamoto R, Uehara T, Yanai T, Takata R, Tanaka T.
- Journal Title
  
  Front Pharmacol.
  
  Volume : 6
- DOI
  10.3389/fphar.2015.00199
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15051
[Journal Article] Downregulation of Stanniocalcin 1 is Responsible for Sorafenib-Induced Cardiotoxicity2015
- Author(s)
  Kawabata M, Umemoto N, Shimada Y, Nishimura Y, Zhang B, Kuroyanagi J, Miyabe M, Tanaka T.
- Journal Title
  
  Toxicological　Siences
  
  Volume : 143 Pages : 374-384
- DOI
  10.1093/toxsci/kfu235
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670127
[Journal Article] Zebrafish as a systems toxicology model for developmental neurotoxicity testing2015
- Author(s)
  Nishimura Y, Murakami S, Ashikawa Y, Sasagawa S, Umemoto N, Shimada Y, Tanaka T.
- Journal Title
  
  Congenital Anomalies
  
  Volume : 55 Issue : 1 Pages : 1-16
- DOI
  10.1111/cga.12079
- ISSN
  0914-3505
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510069, KAKENHI-PROJECT-25670127
[Journal Article] Zinc finger MYND-type containing 8 promotes tumour angiogenesis via induction of vascular endothelial growth factor-A expression2014
- Author(s)
  Junya Kuroyanagi, Yasuhito Shimada, Beibei Zhang, Michiko Ariyoshi, Noriko Umemoto, Yuhei Nishimura, Toshio Tanaka
- Journal Title
  
  FEBS Letters
  
  Volume : 588 Pages : 3409-3416
- DOI
  10.1016/j.febslet.2014.07.033
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670127
[Journal Article] Eriocitrin ameliorates diet-induced hepatic steatosis with activation of mitochondrial biogenesis.2014
- Author(s)
  Masanori Hiramitsu, Yasuhito Shimada,Junya Kuroyanagi,Takashi Inoue,Takao Katagiri,Liqing Zang,Yuhei Nishimura,Norihiro Nishimura & Toshio Tanaka
- Journal Title
  
  Scientific Reports
  
  Volume : 4 Pages : 3708-3708
- DOI
  10.1038/srep03708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670127, KAKENHI-PROJECT-25860294
[Journal Article] Zebrafish xenotransplantation model for cancer stem-like cell study and high-throughput screening of inhibitors.2014
- Author(s)
  Zhang B, Shimada Y, Kuroyanagi J, Nishimura Y, Umemoto N, Nomoto T, Shintou T, Miyazaki T, Tanaka T.
- Journal Title
  
  Tumour Biology
  
  Volume : 35 Pages : 11861-11869
- DOI
  10.1007/s13277-014-2417-8
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670127
[Journal Article] Quantitative Phenotyping-Based In Vivo Chemical Screening in a Zebrafish Model of Leukemia Stem Cell Xenotransplantation2014
- Author(s)
  Beibei Zhang,Yasuhito Shimada,Junya Kuroyanagi,Noriko Umemoto,Yuhei Nishimura,Toshio Tanaka
- Journal Title
  
  PLoS ONE
  
  Volume : 9
- DOI
  10.1371/journal.pone.0085439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670127
[Journal Article] Effects of Yuzu (Citrus junos　Siebold ex Tanaka) peel on the diet-induced obesity in a zebrafish model.2014
- Author(s)
  Liqing Zang, Yasuhito Shimada, Jumpei Kawajiria, Toshio Tanaka, Norihiro Nishimura
- Journal Title
  
  Journal of Functional Foods
  
  Volume : 10 Pages : 499-510
- DOI
  10.1016/j.jff.2014.08.002
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670127, KAKENHI-PROJECT-25860294
[Journal Article] In vivo imaging of the mouse neurovascular unit under chronic cerebral hypoperfusion2014
- Author(s)
  Yata K, Nishimura Y, Unekawa M, Tomita Y, Suzuki N, Tanaka T, Mizoguchi A, Tomimoto H.
- Journal Title
  
  Stroke
  
  Volume : 45 Pages : 3698-3703
- DOI
  10.1161/strokeaha.114.005891
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500422, KAKENHI-PROJECT-24510069, KAKENHI-PROJECT-25670127, KAKENHI-PROJECT-26350981
[Journal Article] Fluorescent-based methods for gene knockdown and functional cardiac imaging in zebrafish.2013
- Author(s)
  Umemoto N, Nishimura Y, Shimada Y, Yamanaka Y, Kishi S, Ito S, Okamori K, Nakamura Y, Kuroyanagi J, Zhang Z, Zang L, Wang Z, Nishimura N, Tanaka T.
- Journal Title
  
  Molecular Biotechnology
  
  Volume : 55 Pages : 131-142
- DOI
  10.1007/s12033-013-9664-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670127, KAKENHI-PROJECT-25860294
[Journal Article] Identification of a Novel Indoline Derivative for in Vivo Fluorescent Imaging of Blood-Brain Barrier Disruption in Animal Models.2013
- Author(s)
  Nishimura Y, Yata K, Nomoto T, Ogiwara T, Watanabe K, Shintou T, Tsuboyama A, Okano M, Umemoto N, Zhang Z, Kawabata M, Zhang B, Kuroyanagi J, Shimada Y, Miyazaki T, Imamura T, Tomimoto H, Tanaka T.
- Journal Title
  
  ACS Chem Neurosci
  
  Volume : 4 Pages : 1183-1193
- DOI
  10.1021/cn400010t
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510069, KAKENHI-PROJECT-25670127
[Journal Article] S-nitrosylation regulates mitochondrial quality control via activation of parkin.2013
- Author(s)
  Ozawa K , Komatsubara AT, Nishimura Y, Sawada T, Kawafune H, Tsumoto H, Tsuji Y, Zhao J, Kyotani Y, Tanaka T, Takahashi R, Yoshizumi M
- Journal Title
  
  Scientific Reports
  
  Volume : 3 Pages : 2202-2202
- DOI
  10.1038/srep02202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590306, KAKENHI-PROJECT-25670127
[Journal Article] Downregulation of max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice.2013
- Author(s)
  Shimada Y, Kuroyanagi J, Zhang B, Ariyoshi M, Umemoto N, Nishimura Y, Tanaka T.
- Journal Title
  
  International Journal of Obesity (Lond)
  
  Volume : 217 Pages : 1-8
- DOI
  10.1038/ijo.2013.217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670127
[Journal Article] A Novel, Reliable Method for Repeated Blood Collection from Aquarium Fish.2013
- Author(s)
  Zang L, Shimada Y, Nishimura Y, Tanaka T, Nishimura N.
- Journal Title
  
  Zebrafish
  
  Volume : 10 Pages : 425-432
- DOI
  10.1089/zeb.2012.0862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670127, KAKENHI-PROJECT-25860294
[Journal Article] A high-throughput fluorescence-based assay system for appetite-regulating gene and drug screening.2012
- Author(s)
  Shimada Y, Hirano M, Nishimura Y, Tanaka T
- Journal Title
  
  PLoS One
  
  Volume : 7
- DOI
  10.1371/journal.pone.0052549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659136, KAKENHI-PROJECT-24590318
[Journal Article] In vivo assessment of the permeability of the blood-brain barrier and blood-retinal barrier to fluorescent indoline derivatives in zebrafish.2012
- Author(s)
  Watanabe K, Nishimura Y, Nomoto T, Umemoto N, Zhang Z, Zhang B, Kuroyanagi J, Shimada Y, Shintou T, Okano M, Miyazaki T, Imamura T, Tanaka T.
- Journal Title
  
  BMC Neuroscience
  
  Volume : 13 Pages : 101-101
- DOI
  10.1186/1471-2202-13-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510069
[Journal Article] Green tea extract suppresses adiposity and affects the expression of lipid metabolism genes in diet-induced obese zebrafish2012
- Author(s)
  Takahiro Hasumura, Yasuhito Shimada,Junya Kuroyanagi, Yuhei Nishimura,Shinichi Meguro, Yoshinori Takema and Toshio Tanaka
- Journal Title
  
  Nutrition & Metabolism
  
  Volume : 9 Pages : 73-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659136
[Journal Article] A High-Throughput Fluorescence-Based Assay System for Appetite-Regulating Gene and Drug Screening2012
- Author(s)
  Shimada Y, Hirano M, Nishimura Y,Tanaka T
- Journal Title
  
  PLoS ONE
  
  Volume : 7(12)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659136
[Journal Article] Green tea extract suppresses adiposity and affects the expression of lipid metabolism genes in diet-induced obese zebrafish2012
- Author(s)
  Takahiro Hasumura, Yasuhito Shimada, Junya Kuroyanagi,Yuhei Nishimura, Shinichi Meguro, Yoshinori Takema and Toshio Tanaka
- Journal Title
  
  Nutrition & Metabolism
  
  Volume : 9 Pages : 73-73
- DOI
  10.1186/1743-7075-9-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659136
[Journal Article] Transcriptome analysis of anti-fatty liver action by Campari tomato using a zebrafish diet-induced obesity model.2011
- Author(s)
  Tainaka T, Shimada Y, Kuroyanagi J, Zang L, Oka T, Nishimura Y, Nishimura N, Tanaka T.
- Journal Title
  
  Nutrition & metabolism
  
  Volume : 8 Pages : 88-88
- DOI
  10.1186/1743-7075-8-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659136
[Journal Article] A novel protocol for the oral administration of test chemicals to adultz zebrafish2011
- Author(s)
  Liqing Zang, Daizo Morikane, Yasuhito Shimada, Toshio Tanaka, and Norihiro Nishimura
- Journal Title
  
  Zebrafish December
  
  Volume : 8(4) Pages : 203-210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659136
[Journal Article] A novel protocol for the oral administration of test chemicals to adult zebrafish.2011
- Author(s)
  Zang L, Morikane D, Shimada Y, Tanaka T, Nishimura N.
- Journal Title
  
  Zebrafish
  
  Volume : 8 Pages : 203-220
- DOI
  10.1089/zeb.2011.0726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659136
[Journal Article] Potential role for heat shock protein 72 in antagonizing cerebral vasospasm after rat subarachnoid hemorrhage.2004
- Author(s)
  Hirofumi Nikaido, Hiroshi Tsunoda, Yuhei Nishimura, Takaaki Kirino, Toshio Tanaka
- Journal Title
  
  Circulation 110(13)
  
  Pages : 1839-1846
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207003
[Journal Article] Genomic organization, chromosomal localization, and alternative splicing of the human phosphodiesterase 8B gene.2002
- Author(s)
  M.Hayashi, Y.Shimada, Y.Nishimura, T.Hama, T.Tanaka
- Journal Title
  
  Biochem.Biophys.Res.Commun. 297
  
  Pages : 1253-1258
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207003
[Presentation] Differentially Expressed Genes in Early and Late Treatment for Occlusive Pulmonary Vasculopathy in Sugen/hypoxia Models: Molecular Basis for Early Treatment2017
- Author(s)
  Yoshihide Mitani, Hirofumi Sawada, Tsutomu Shinohara, Shoichiro Otsuki, Noriko Yodoya, Hiroyuki Ohashi, Taichi Kato, Erquan Zhang, Yuhei Nishimura, Toshio Tanaka, Kazuo Maruyama, Masahiro Hirayama.
- Organizer
  American Heart Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09688
[Presentation] 肥大型心筋症の新規関連遺伝子GSTK1の発見と機能解析2016
- Author(s)
  西村有平、笹川翔太、岡部志功、村上宗一郎、芦川芳史、弓削瑞葵、川口幸輝、島田康人、岡本隆二、伊藤正明、田中利男
- Organizer
  第26回日本循環薬理学会
- Place of Presentation
  信州大学（長野県・松本市）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-16K08547
[Presentation] 分子標的薬の心毒性に関するシステムズ薬理学2015
- Author(s)
  西村有平
- Organizer
  第44回日本心脈管作動物質学会
- Place of Presentation
  高松センタービル
- Year and Date
  2015-02-06
- Data Source
  KAKENHI-PROJECT-25670127
[Presentation] ゼブラフィッシュを用いた創薬スクリーニング2015
- Author(s)
  西村有平、川瀬玲子、田中利男
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学
- Year and Date
  2015-03-27
- Invited
- Data Source
  KAKENHI-PROJECT-24510069
[Presentation] ゼブラフィッシュを用いた創薬スクリーニング2015
- Author(s)
  西村有平
- Organizer
  日本薬学会第135回年会
- Place of Presentation
  神戸学院大学
- Year and Date
  2015-03-27
- Invited
- Data Source
  KAKENHI-PROJECT-25670127
[Presentation] Systems Pharmacology for Retinal Diseases2015
- Author(s)
  Nishimura Y, Kawase R, Tanaka T
- Organizer
  The 88th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-20
- Invited
- Data Source
  KAKENHI-PROJECT-24510069
[Presentation] システムズ薬理学を用いた網膜疾患の病態解析2015
- Author(s)
  西村有平
- Organizer
  第88回日本薬理学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-25670127
[Presentation] 遺伝子ノックアウトゼブラフィッシュを用いたニコチンの発達神経毒性評価2014
- Author(s)
  西村有平
- Organizer
  第41回日本毒性学会
- Place of Presentation
  神戸コンベンションセンター
- Year and Date
  2014-07-03
- Data Source
  KAKENHI-PROJECT-25670127
[Presentation] 遺伝子改変ゼブラフィッシュを用いたニコチンの発達神経毒性評価2014
- Author(s)
  西村有平、村上宗一郎、芦川芳史、笹川翔太、川端美湖、梅本紀子、有吉美稚子、張貝貝、島田康人、田中利男
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸コンベンションセンター
- Year and Date
  2014-07-03
- Data Source
  KAKENHI-PROJECT-24510069
[Presentation] HSP90阻害薬の網膜毒性に関するシステムズ薬理学2014
- Author(s)
  西村有平
- Organizer
  第9回日本ケミカルバイオロジー学会
- Place of Presentation
  東北大学川内キャンパス
- Year and Date
  2014-06-11
- Data Source
  KAKENHI-PROJECT-25670127
[Presentation] ソラフェニブの心毒性にはstanniocalcin1が関与する2014
- Author(s)
  西村有平
- Organizer
  第24回日本循環薬理学会
- Place of Presentation
  山形テルサ
- Year and Date
  2014-12-05
- Data Source
  KAKENHI-PROJECT-25670127
[Presentation] ゼブラフィッシュを用いたBBB機能イメージング2014
- Author(s)
  西村有平
- Organizer
  第９回トランスポーター研究会年会
- Place of Presentation
  名古屋市立大学
- Year and Date
  2014-06-14
- Invited
- Data Source
  KAKENHI-PROJECT-25670127
[Presentation] ゼブラフィッシュによる新しい網膜保護機構解析2014
- Author(s)
  西村有平
- Organizer
  第34回日本眼薬理学会
- Place of Presentation
  長良川国際会議場
- Year and Date
  2014-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-25670127
[Presentation] ゼブラフィッシュを用いた医薬品の発達神経毒性のシステムズ薬理学2014
- Author(s)
  西村有平
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  東北大学萩ホール・仙台国際センター
- Data Source
  KAKENHI-PROJECT-25670127
[Presentation] ゼブラフィッシュを用いたBBB機能イメージング2014
- Author(s)
  西村有平、梅本紀子、田中利男
- Organizer
  第9回トランスポーター研究会年会
- Place of Presentation
  名古屋市立大学
- Year and Date
  2014-06-14
- Invited
- Data Source
  KAKENHI-PROJECT-24510069
[Presentation] ゼブラフィッシュによる医薬品の生殖発生毒性評価2014
- Author(s)
  西村有平、田中利男、島田康人、梅本紀子
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸コンベンションセンター
- Year and Date
  2014-07-03
- Invited
- Data Source
  KAKENHI-PROJECT-24510069
[Presentation] Arp1遺伝子のノックダウンによる視細胞形成障害は、繊毛症による視細胞変性と類似する2013
- Author(s)
  西村有平
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25670127
[Presentation] ゼブラフィッシュ胚を用いた新しい発達神経毒性評価システム2013
- Author(s)
  西村有平
- Organizer
  第53回日本先天異常学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-25670127
[Presentation] 新しいin vivo イメージングとオミックス創薬2012
- Author(s)
  西村有平
- Organizer
  第85回日本薬理学会
- Place of Presentation
  京都国際会館
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-23659136
[Presentation] 新しいin vivoイメージングとオミックス創薬2012
- Author(s)
  西村　有平
- Organizer
  第85回日本薬理学会年会(招待講演)
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23659136
[Presentation] A Novel System for Detecting Developmental Neurotoxicity of Chemicals using Zebrafish2012
- Author(s)
  Nishimura Y
- Organizer
  2012 ICCA-LRI and UK HPA Workshop Technologies to Inform Chemical Safety Sciences
- Place of Presentation
  Budapest, Hungary
- Data Source
  KAKENHI-PROJECT-24510069
[Presentation] ゼブラフィッシュを用いた網膜毒性評価
- Author(s)
  西村有平
- Organizer
  第28回比較眼科学会基礎部会研究会
- Place of Presentation
  大日本住友製薬㈱大阪研究所
- Data Source
  KAKENHI-PROJECT-25670127
[Presentation] ゼブラフィッシュによる新しい網膜保護機構解析
- Author(s)
  西村有平、梅本紀子、田中利男
- Organizer
  第34回日本眼薬理学会年会
- Place of Presentation
  長良川国際会議場
- Year and Date
  2014-09-13 – 2014-09-15
- Invited
- Data Source
  KAKENHI-PROJECT-24510069
[Presentation] ゼフラフィッシュを用いた網膜毒性評価
- Author(s)
  西村有平
- Organizer
  比較眼科学会基礎部会
- Place of Presentation
  住友化学
- Invited
- Data Source
  KAKENHI-PROJECT-24510069
[Presentation] In vivo fluorescent imaging of blood-brain barrier disruption in zebrafish using a novel dye.
- Author(s)
  Nishimura Y, Murakami S, Ashikawa Y, Sasagawa S, Umemoto N, Shimada Y, Tanaka T.
- Organizer
  DNT4
- Place of Presentation
  The Inn at Penn, Philadelphia, PA
- Year and Date
  2014-05-11 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-24510069
[Presentation] ゼブラフィッシュを用いたHSP90阻害薬の網膜毒性発現機構解析
- Author(s)
  西村有平
- Organizer
  第40回日本毒性学会学術年会
- Place of Presentation
  幕張メッセ千葉
- Data Source
  KAKENHI-PROJECT-25670127
[Presentation] 新しい網膜変性疾患モデルの創成と機能解析
- Author(s)
  西村有平
- Organizer
  第124回日本薬理学会近畿部会
- Place of Presentation
  京都ガーデンパレス
- Data Source
  KAKENHI-PROJECT-25670127
[Presentation] バルプロ酸による催奇形性のシステムズ薬理学
- Author(s)
  村上宗一郎、西村有平、笹川翔太、芦川芳史、川端美湖、張貝貝、島田康人、梅本紀子、田中利男
- Organizer
  第54回日本先天異常学会学術年会
- Place of Presentation
  麻布大学
- Year and Date
  2014-07-26 – 2014-07-27
- Data Source
  KAKENHI-PROJECT-24510069
[Presentation] ゼブラフィッシュを用いた新しい発達神経毒性評価システム
- Author(s)
  西村有平、島田康人、田中利男
- Organizer
  日本先天異常学会
- Place of Presentation
  千里ライフサイエンスセンター
- Invited
- Data Source
  KAKENHI-PROJECT-24510069

1. TANAKA Toshio (00135443)

# of Collaborated Projects : 21results

# of Collaborated Products : 47results
2. NAKA Michiko (10093139)

# of Collaborated Projects : 14results

# of Collaborated Products : 2results
3. TSUNODA Hiroshi (20314114)

# of Collaborated Projects : 10results

# of Collaborated Products : 1results
4. SHIMADA Yasuhito (40378427)

# of Collaborated Projects : 5results

# of Collaborated Products : 27results
5. HAYASHI Masaaki (80291417)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
6. UMEMOTO Noriko (40649365)

# of Collaborated Projects : 2results

# of Collaborated Products : 16results
7. INADA Hiroyasu (90283522)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
8. Kawase Reiko (50746740)

# of Collaborated Projects : 2results

# of Collaborated Products : 6results
9. 白水崇 (00582678)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
10. 稲垣昌樹 (30183007)

# of Collaborated Projects : 2results

# of Collaborated Products : 1results
11. Mitani Yoshihide (60273380)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
12. 丸山一男 (20181828)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
13. 澤田博文 (30362354)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
14. 中谷中 (80237304)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. ASAHI Yoshihiko

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. BERCHTOLD M.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. HEIZMANN C.W

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. TANAKA Kenji

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
19. SUZUKI Norihiro

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
20. 臧黎清

# of Collaborated Projects : 0results

# of Collaborated Products : 4results
21. 笠原広介

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
22. 五島直樹

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
23. 田中宏樹

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
24. 木村章彦

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
25. 近藤稔和

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
26. 小澤健太郎

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
27. 吉栖正典

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
28. 冨田裕

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
29. 畝川美悠紀

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

NISHIMURA Yuuhei 西村 有平

NISHIMURA Yuhei 西村 有平

Research Projects

Research Products

Co-Researchers

複合的アプローチを用いた多発性嚢胞腎の新規病態メカニズム解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

一次線毛の動態制御によるがん治療法開発を志向したマルチオミックス解析Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新しい肥大型心筋症病態遺伝子のシステムズ薬理学Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of zebrafish-based assay to detect developmental neurotoxicity of irradiation and to identify protectants against the neurotoxicityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

遺伝子発現プロファイルに基づく降圧薬のクラスタリングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

NISHIMURA Yuuhei 西村有平

NISHIMURA Yuhei 西村有平