Saito Takuro 西塔拓郎

Researcher Number	20646468
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 特任准教授(常勤)
Affiliation (based on the past Project Information) *help	2025: 大阪大学, 大学院医学系研究科, 特任准教授(常勤) 2022 – 2024: 大阪大学, 大学院医学系研究科, 助教 2021: 大阪大学, 医学系研究科, 助教 2020: 大阪大学, 医学系研究科, 特任助教(常勤) 2020: 大阪大学, 大学院医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related Except Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 50010:Tumor biology-related / Basic Section 56030:Urology-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 59010:Rehabilitation science-related
Keywords	Principal Investigator 免疫チェックポイント分子 / T細胞疲弊化 / リンパ節 / 胃癌 / Precursor T細胞 / 抗PD1抗体 / 所属リンパ節 / 免疫抑制機構 / 胃癌リンパ節 / PD1 / PD-L1 / PD-1 / エクソソーム … More Except Principal Investigator … More 制御性T細胞 / 胃癌 / 食道癌 / 侵襲反応 / カウンターホルモン / 術後血糖 / 遺伝子変異 / 微小免疫環境 / HP感染 / CCL1 / CCR8 / 腫瘍免疫環境 / ISH法 / CCR8発現細胞 / CCL1発現細胞 / 血液 / 細菌叢 / Ｄアミノ酸 / CD31 / 血管新生 / 尿路上皮癌 / 腎細胞癌 / エクソソーム / Cutibacterium acnes / 細胞外小胞 / Firmicutes / 癌免疫療法 / 細菌関連代謝物 / 血液内細菌叢 / 術前除菌 / ICOS / H. pylori / ICOS+ Treg / 除菌 / H.pylori / ICOS陽性Treg / スリーブ状胃切除 / 2型糖尿病 / 腸内細菌叢 / 減量効果・糖尿病改善効果 / 腹腔鏡下スリーブ状胃切除術 / 減量・代謝改善手術 / 栄養療法 / 術前リハビリテーション / 筋肉量 / アプリ / リハビリテーション / 術前リハ栄養 / 栄養 / リハビリ / サルコペニア / 癌治療 / 高齢者 / 術前化学療法 / 運動栄養介入 / 運動・栄養介入 / フレイル / 高齢癌患者 Less

ピロリ菌除菌後胃癌における遺伝子異常と抗腫瘍免疫応答の解明
- Principal Investigator
  
  中本蓮之助
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Osaka
食道癌における治療反応性高血糖が予後に与える影響とそのメカニズム解析
- Principal Investigator
  
  山下公太郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  The University of Osaka
CCL1-CCR8経路を介した腫瘍内Treg制御による治療法の探索
- Principal Investigator
  
  中井慈人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Osaka University
ニボルマブ結合T細胞検出法を用いた免疫チェックポイント阻害薬の治療効果機序の解明Principal Investigator
- Principal Investigator
  
  西塔拓郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
周術期H.pylori除菌の胃癌予後改善効果：ICOS発現Tregの制御
- Principal Investigator
  
  浦川真哉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
Elucidation of the cancer local immune status constructed by the systemic circulating microbiome and bacterial-related metabolism in urogenital cancer
- Principal Investigator
  
  河嶋厚成
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University
Development of preoperative rehabilitation and nutritional support program for improving treatment outcome of elderly gastric cancer patients
- Principal Investigator
  
  Yamamoto Kazuyoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Osaka University
腸内細菌叢(特にAM菌)と肥満・糖尿病外科手術後減量・糖尿病改善効果の関連の解明
- Principal Investigator
  
  山口剛
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Shiga University of Medical Science
A trial of exercise and nutrition treatment for aged esophageal cancer patients undergoing neoadjuvant chemotherapy
- Principal Investigator
  
  YAMASAKI Makoto
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kansai Medical University
  Osaka University
The analysis for the suppressive mechanism of antitumor immunity in lymph nods of gastric cancerPrincipal Investigator
- Principal Investigator
  
  Saito Takuro
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Cutibacterium acnes‐derived extracellular vesicles promote tumor growth in renal cell carcinoma2024
- Author(s)
  Jingushi Kentaro、Kawashima Atsunari、Tanikawa Sayaka、Saito Takuro、Yamamoto Akinaru、Uemura Toshihiro、Sassi Nesrine、Ishizuya Yu、Yamamoto Yoshiyuki、Kato Taigo、Hatano Koji、Hase Hiroaki、Nonomura Norio、Tsujikawa Kazutake
- Journal Title
  
  Cancer Science
  
  Volume: 1 Issue: 8 Pages: 1-1
- DOI
  10.1111/cas.16202
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24472
[Journal Article] Integrated analysis of phase 1a and 1b randomized controlled trials; Treg-targeted cancer immunotherapy with the humanized anti-CCR4 antibody, KW-0761, for advanced solid tumors2023
- Author(s)
  Fujikawa Kaoru、Saito Takuro、Kurose Koji、Kojima Takashi、Funakoshi Takeru、Sato Eiichi、Kakimi Kazuhiro、Iida Shinsuke、Doki Yuichiro、Oka Mikio、Ueda Ryuzo、Wada Hisashi
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 9 Pages: 0291772-0291772
- DOI
  10.1371/journal.pone.0291772
- Data Source
  KAKENHI-PROJECT-23K08194
[Journal Article] C-reactive protein kinetics as a predictive marker for long-term outcome of immune checkpoint inhibitors in oesophagogastric cancer2023
- Author(s)
  Nose Yohei、Saito Takuro、Kurokawa Yukinori、Takahashi Tsuyoshi、Yamamoto Kazuyoshi、Momose Kota、Yamashita Kotaro、Tanaka Koji、Makino Tomoki、Eguchi Hidetoshi、Doki Yuichiro、Wada Hisashi
- Journal Title
  
  BJC Reports
  
  Volume: 1 Issue: 1 Pages: 7-7
- DOI
  10.1038/s44276-023-00005-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08194
[Journal Article] Bacteria-derived DNA in serum extracellular vesicles are biomarkers for renal cell carcinoma2023
- Author(s)
  Uemura Toshihiro、Kawashima Atsunari、Jingushi Kentaro、Motooka Daisuke、Saito Takuro、Nesrine Sassi、Oka Toshiki、Okuda Yohei、Yamamoto Akinaru、Yamamichi Gaku、Tomiyama Eisuke、Ishizuya Yu、Yamamoto Yoshiyuki、Kato Taigo、Hatano Koji、Tsujikawa Kazutake、Wada Hisashi、Nonomura Norio
- Journal Title
  
  Heliyon
  
  Volume: 9 Issue: 9 Pages: e19800-e19800
- DOI
  10.1016/j.heliyon.2023.e19800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09469, KAKENHI-PROJECT-23K24472
[Journal Article] Density and maturity of peritumoral tertiary lymphoid structures in oesophageal squamous cell carcinoma predicts patient survival and response to immune checkpoint inhibitors.2023
- Author(s)
  Hayashi Y, Makino T, Sato E, Ohshima K, Nogi Y, Kanemura T, Honma K, Yamashita K, Saito T, Tanaka K, Yamamoto K, Takahashi T, Kurokawa Y, Miyata H, Nakajima K, Wada H, Morii E, Eguchi H, Doki Y.
- Journal Title
  
  Br J Cancer.
  
  Volume: - Issue: 12 Pages: 2175-2185
- DOI
  10.1038/s41416-023-02235-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08776, KAKENHI-PROJECT-22K07278, KAKENHI-PROJECT-23K08194
[Journal Article] Propranolol suppresses gastric cancer cell growth by regulating proliferation and apoptosis2021
- Author(s)
  Koh Masahiro、Takahashi Tsuyoshi、Kurokawa Yukinori、Kobayashi Teruyuki、Saito Takuro、Ishida Tomo、Serada Satoshi、Fujimoto Minoru、Naka Tetsuji、Wada Noriko、Yamashita Kotaro、Tanaka Koji、Miyazaki Yasuhiro、Makino Tomoki、Nakajima Kiyokazu、Yamasaki Makoto、Eguchi Hidetoshi、Doki Yuichiro
- Journal Title
  
  Gastric Cancer
  
  Volume: 24 Issue: 5 Pages: 1037-1049
- DOI
  10.1007/s10120-021-01184-7
- NAID
  40022652391
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17685
[Journal Article] Taste alteration after gastrectomy in patients with gastric cancer2021
- Author(s)
  Hagi Takaomi、Kurokawa Yukinori、Takahashi Tsuyoshi、Saito Takuro、Yamashita Kotaro、Tanaka Koji、Makino Tomoki、Yamasaki Makoto、Motoori Masaaki、Kimura Yutaka、Nakajima Kiyokazu、Eguchi Hidetoshi、Doki Yuichiro
- Journal Title
  
  Surgery Today
  
  Volume: 51 Issue: 5 Pages: 777-784
- DOI
  10.1007/s00595-020-02194-1
- Data Source
  KAKENHI-PROJECT-20K17685
[Presentation] CRP推移による胃癌免疫チェックポイント阻害薬のアウトカム予測2023
- Author(s)
  西塔拓郎
- Organizer
  第27回日本がん免疫学会
- Data Source
  KAKENHI-PROJECT-23K08194
[Presentation] CRP kinetics as a predictive marker for outcome to immune checkpoint inhibitors in upper gastrointestinal cancer2023
- Author(s)
  西塔拓郎
- Organizer
  第82回日本癌学会
- Data Source
  KAKENHI-PROJECT-23K08194
[Presentation] 術前ピロリ菌除菌が抗腫瘍免疫を介して胃癌の予後に与える影響2022
- Author(s)
  西塔拓郎
- Organizer
  日本外科学会
- Data Source
  KAKENHI-PROJECT-22K08846

1. 黒川幸典 (10470197)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
2. 山下公太郎 (20747159)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 和田尚 (70243459)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. 田中晃司 (70621019)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 牧野知紀 (80528620)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 高橋剛 (50452389)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. YAMASAKI Makoto (50444518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Yamamoto Kazuyoshi (70528637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 松浦記大 (90804477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山口剛 (10510290)

# of Collaborated Projects: 1 results

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11. 谷眞至 (60236677)

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12. 大城崇司 (60404563)

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13. 太田正之 (80271104)

# of Collaborated Projects: 1 results

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14. 井上健太郎 (90368209)

# of Collaborated Projects: 1 results

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15. 井本博文 (20754922)

# of Collaborated Projects: 1 results

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16. 加野将之 (20456023)

# of Collaborated Projects: 1 results

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17. 浦川真哉 (40768975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 河嶋厚成 (50746568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 木村友則 (00631300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 元岡大祐 (10636830)

# of Collaborated Projects: 1 results

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21. 野々村祝夫 (30263263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. 神宮司健太郎 (80707571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. 中井慈人 (40912027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 中本蓮之助 (31001430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 植村俊彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 土岐祐一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Saito Takuro 西塔 拓郎

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ニボルマブ結合T細胞検出法を用いた免疫チェックポイント阻害薬の治療効果機序の解明Principal Investigator

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The analysis for the suppressive mechanism of antitumor immunity in lymph nods of gastric cancerPrincipal Investigator

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[Journal Article] Cutibacterium acnes‐derived extracellular vesicles promote tumor growth in renal cell carcinoma2024

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[Journal Article] Integrated analysis of phase 1a and 1b randomized controlled trials; Treg-targeted cancer immunotherapy with the humanized anti-CCR4 antibody, KW-0761, for advanced solid tumors2023

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[Journal Article] C-reactive protein kinetics as a predictive marker for long-term outcome of immune checkpoint inhibitors in oesophagogastric cancer2023

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[Journal Article] Bacteria-derived DNA in serum extracellular vesicles are biomarkers for renal cell carcinoma2023

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[Journal Article] Density and maturity of peritumoral tertiary lymphoid structures in oesophageal squamous cell carcinoma predicts patient survival and response to immune checkpoint inhibitors.2023

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Saito Takuro 西塔拓郎