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UMEDA Masataka  梅田 雅孝

… Alternative Names

Umeda Masataka  梅田 雅孝

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Researcher Number 20750053
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-6647-7130
Affiliation (Current) 2025: 長崎大学, 病院(医学系), 助教
Affiliation (based on the past Project Information) *help 2022 – 2024: 長崎大学, 病院(医学系), 助教
2021 – 2022: 長崎大学, 医歯薬学総合研究科(医学系), 助教
2016 – 2018: 長崎大学, 病院(医学系), 助教
Review Section/Research Field
Principal Investigator
Basic Section 54020:Connective tissue disease and allergy-related / 0902:General internal medicine and related fields / Collagenous pathology/Allergology
Except Principal Investigator
Basic Section 57060:Surgical dentistry-related
Keywords
Principal Investigator
T細胞 / 全身性エリテマトーデス / 家族性地中海熱 / ADAM / SLE / 自己免疫疾患 / セクレトーム / プロテイナーゼ / Secretome解析 / メタロプロテイナーゼ … More / プロテオミクス / マイクロアレイ / 臨床 / 免疫学 / CD52 … More
Except Principal Investigator
再生 / 細胞治療 / シェーグレン症候群 / 唾液腺 Less
  • Research Projects

    (6 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (18 People)
  •  ナノリポソームを用いたドラッグデリバリーによる自己炎症性疾患の治療戦略Principal Investigator

    • Principal Investigator
      梅田 雅孝
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Nagasaki University
  •  自己免疫疾患における所属リンパ節の免疫機能是正を標的軸としたデザイナー細胞の開発

    • Principal Investigator
      井 隆司
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Nagasaki University
  •  ADAMを介した全身性エリテマトーデスにおけるTh17細胞分化制御機構の解明Principal Investigator

    • Principal Investigator
      梅田 雅孝
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Nagasaki University
  •  Elucidation of the pathogenic mechanisms of Systemic Lupus Erythematosus using T cell Secretome analysisPrincipal Investigator

    • Principal Investigator
      Umeda Masataka
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0902:General internal medicine and related fields
    • Research Institution
      Nagasaki University
  •  全身性エリテマトーデスにおけるSiglec-10を介した免疫調節に関する研究Principal Investigator

    • Principal Investigator
      梅田 雅孝
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Nagasaki University
  •  CD4+ CD52lo T-cell expression contributes to the development of systemic lupus erythematosus.Principal Investigator

    • Principal Investigator
      UMEDA Masataka
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Nagasaki University

All 2023 2022 2021 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] Inhibition of calcium/calmodulin-dependent protein kinase IV in arthritis: dual effect on Th17 cell activation and osteoclastogenesis2023

    • Author(s)
      Tomohiro Koga, Masataka Umeda, Nobuya Yoshida, Yushiro Endo, Atsushi Kawakami, George C Tsokos
    • Journal Title

      Rheumatology (Oxford)

      Volume: 62 Issue: 2 Pages: 861-871

    • DOI

      10.1093/rheumatology/keac381

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17888, KAKENHI-PROJECT-22K16362, KAKENHI-PROJECT-21K20905
  • [Journal Article] Chest pain and Raynaud’s phenomenon after COVID-19 vaccination in a patient previously diagnosed with systemic lupus erythematosus: a case report2023

    • Author(s)
      Kawano Hiroaki、Umeda Masataka、Okano Shinji、Kudo Takashi
    • Journal Title

      European Heart Journal - Case Reports

      Volume: 7 Issue: 3

    • DOI

      10.1093/ehjcr/ytad102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K16362, KAKENHI-PROJECT-21K20905
  • [Journal Article] Immunoglobulin G4-related Disease with Marked Eosinophilia: A Case Report and Literature Review2023

    • Author(s)
      Origuchi Tomoki、Uchida Tomohisa、Sakaguchi Tatsuki、Matsuo Haruna、Michitsuji Toru、Umeda Masataka、Shimizu Toshimasa、Koga Tomohiro、Kawashiri Shin-Ya、Iwamoto Naoki、Ichinose Kunihiro、Tamai Mami、Ichinose Masahiro、Ando Koji、Horie Ichiro、Nakao Nobuhiro、Irie Junji、Kawakami Atsushi
    • Journal Title

      Intern. Med.

      Volume: 62 Issue: 12 Pages: 1849-1855

    • DOI

      10.2169/internalmedicine.0453-22

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2023-06-15
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08439, KAKENHI-PROJECT-22K16362, KAKENHI-PROJECT-21K20905
  • [Journal Article] A Disintegrin and metalloproteinase carves T cell abnormalities and pathogenesis in systemic lupus erythematosus2023

    • Author(s)
      Masataka Umeda , Abhigyan Satyam, Nobuya Yoshida, Atsushi Kawakami
    • Journal Title

      Clinical Immunology

      Volume: - Pages: 110168-110168

    • DOI

      10.1016/j.clim.2024.110168

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16362
  • [Journal Article] A Patient with Severe Fever with Thrombocytopenia Syndrome, Activated Partial Thromboplastin Time Prolongation, and Transient Antiphospholipid Antibodies2023

    • Author(s)
      Tsukamoto Yutaka、Sugimoto Takashi、Umeda Masataka、Kato Takeharu、Hiura Yukari、Morita Kouichi、Ariyoshi Koya
    • Journal Title

      Intern. Med.

      Volume: 62 Issue: 14 Pages: 2145-2149

    • DOI

      10.2169/internalmedicine.0782-22

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2023-07-15
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K16362, KAKENHI-PROJECT-21K20905
  • [Journal Article] Comparison of complications during 1-year follow-up between remitting seronegative symmetrical synovitis with pitting edema syndrome and elderly-onset rheumatoid arthritis2022

    • Author(s)
      Origuchi Tomoki、Umeda Masataka、Koga Tomohiro、Kawashiri Shin-ya、Iwamoto Naoki、Ichinose Kunihiro、Tamai Mami、Tsukada Toshiaki、Miyashita Taiichiro、Iwanaga Nozomi、Horai Yoshiro、Arima Kazuhiko、Aramaki Toshiyuki、Ueki Yukitaka、Eguchi Katsumi、Kawakami Atsushi
    • Journal Title

      Immunological Medicine

      Volume: - Issue: 3 Pages: 1-7

    • DOI

      10.1080/25785826.2022.2046307

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08439, KAKENHI-PROJECT-21K20905, KAKENHI-PROJECT-22K16352, KAKENHI-PROJECT-22K16362
  • [Journal Article] Glutaminase 2 Promotes Interleukin‐2 Production in CD4+ T cells by Supporting Antioxidant Defense2022

    • Author(s)
      Hisada Ryo、Yoshida Nobuya、Orite Seo Yeon K.、Umeda Masataka、Burbano Catalina、Scherlinger Marc、Kono Michihito、Krishfield Suzanne、Tsokos George C.
    • Journal Title

      Arthritis & Rheumatology

      Volume: 7 Issue: 7 Pages: 1204-1210

    • DOI

      10.1002/art.42112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K20905
  • [Journal Article] Severe Anemia Due to Cold Agglutinin Syndrome in a COVID-19 Patient with IgM Monoclonal Gammopathy of Undetermined Significance Successfully Treated with Corticosteroids2022

    • Author(s)
      Tsukamoto Yutaka、Umeda Masataka、Muto Yuko、Sugimoto Takashi、Yamauchi Momoko、Ando Koji、Ariyoshi Koya
    • Journal Title

      Intern. Med.

      Volume: 61 Issue: 11 Pages: 1789-1793

    • DOI

      10.2169/internalmedicine.8647-21

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2022-06-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K20905
  • [Journal Article] Clinical Characteristics of Patients With IgG4-Related Disease Complicated by Hypocomplementemia2022

    • Author(s)
      Fujita Yuya、Fukui Shoichi、Umeda Masataka、Tsuji Sosuke、Iwamoto Naoki、Nakashima Yoshikazu、Horai Yoshiro、Suzuki Takahisa、Okada Akitomo、Aramaki Toshiyuki、Ueki Yukitaka、Mizokami Akinari、Origuchi Tomoki、Watanabe Hiroshi、Migita Kiyoshi、Kawakami Atsushi
    • Journal Title

      Frontiers in Immunology

      Volume: 13 Pages: 828122-828122

    • DOI

      10.3389/fimmu.2022.828122

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16210, KAKENHI-PROJECT-21K08439, KAKENHI-PROJECT-21K20905
  • [Journal Article] The deacetylase SIRT2 contributes to autoimmune disease pathogenesis by modulating IL-17A and IL-2 transcription2022

    • Author(s)
      Hisada Ryo、Yoshida Nobuya、Umeda Masataka、Burbano Catalina、Bhargava Rhea、Scherlinger Marc、Kono Michihito、Kyttaris Vasileios C.、Krishfield Suzanne、Tsokos George C.
    • Journal Title

      Cellular & Molecular Immunology

      Volume: 19 Issue: 6 Pages: 738-750

    • DOI

      10.1038/s41423-022-00874-1

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16362, KAKENHI-PROJECT-21K20905
  • [Journal Article] Phosphofructokinase P fine-tunes T regulatory cell metabolism, function, and stability in systemic autoimmunity2022

    • Author(s)
      Scherlinger Marc、Pan Wenliang、Hisada Ryo、Boulougoura Afroditi、Yoshida Nobuya、Vukelic Milena、Umeda Masataka、Krishfield Suzanne、Tsokos Maria G.、Tsokos George C.
    • Journal Title

      Science Advances

      Volume: 8 Issue: 48

    • DOI

      10.1126/sciadv.adc9657

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16362, KAKENHI-PROJECT-21K20905
  • [Journal Article] Atypical Cogan's Syndrome Mimicking Giant Cell Arteritis Successfully Treated with Early Administration of Tocilizumab2022

    • Author(s)
      Hara Kazusato、Umeda Masataka、Segawa Keiko、Akagi Midori、Endo Yushiro、Koga Tomohiro、Kawashiri Shin-ya、Ichinose Kunihiro、Nakamura Hideki、Maeda Takahiro、Kawakami Atsushi
    • Journal Title

      Intern. Med.

      Volume: 61 Issue: 8 Pages: 1265-1270

    • DOI

      10.2169/internalmedicine.7674-21

    • NAID

      130008101318

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2022-04-15
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K20905
  • [Journal Article] Prediction of radiographic progression during a treat-to-target strategy by the sequential application of MRI-proven bone marrow oedema and power-Doppler grade ≧2 articular synovitis in rheumatoid arthritis: Retrospective observational study2022

    • Author(s)
      Takatani Ayuko、Tamai Mami、Ohki Nozomi、Okamoto Momoko、Endo Yushiro、Tsuji Sousuke、Shimizu Toshimasa、Umeda Masataka、Fukui Shoichi、Sumiyoshi Remi、Nishino Ayako、Koga Tomohiro、Kawashiri Shin-ya、Iwamoto Naoki et al.
    • Journal Title

      Modern Rheumatology

      Volume: - Issue: 4 Pages: 708-714

    • DOI

      10.1093/mr/roac077

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08439, KAKENHI-PROJECT-21K08461, KAKENHI-PROJECT-22K16362, KAKENHI-PROJECT-21K20905
  • [Journal Article] Serum checkpoint molecules in patients with IgG4-related disease (IgG4-RD)2021

    • Author(s)
      Matsumoto Haruki、Fujita Yuya、Matsuoka Naoki、Temmoku Jumpei、Yashiro-Furuya Makiko、Asano Tomoyuki、Sato Shuzo、Watanabe Hiroshi、Suzuki Eiji、Tsuji Sosuke、Fukui Shoichi、Umeda Masataka、Iwamoto Naoki、Kawakami Atsushi、Migita Kiyoshi
    • Journal Title

      Arthritis Research & Therapy

      Volume: 23 Issue: 1

    • DOI

      10.1186/s13075-021-02527-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K20905
  • [Journal Article] ADAM9 enhances Th17 cell differentiation and autoimmunity by activating TGF-β12021

    • Author(s)
      Umeda Masataka、Yoshida Nobuya、Hisada Ryo、Burbano Catalina、Orite Seo Yeon K.、Kono Michihito、Kyttaris Vasileios C.、Krishfield Suzanne、Owen Caroline A.、Tsokos George C.
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 118 Issue: 18

    • DOI

      10.1073/pnas.2023230118

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K20905
  • [Journal Article] Granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-α in combination is a useful diagnostic biomarker to distinguish familial Mediterranean fever from sepsis2021

    • Author(s)
      Koga T, Furukawa K, Migita K, Morimoto S, Shimizu T, Fukui S, Umeda M, Endo Y, Sumiyoshi R, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Origuchi T, Maeda T, Yachie A, Kawakami A.
    • Journal Title

      Arthritis Res Ther.

      Volume: 23 Issue: 1 Pages: 260-260

    • DOI

      10.1186/s13075-021-02644-2

    • NAID

      120007180588

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08913, KAKENHI-PROJECT-21K20905
  • [Journal Article] Intravenous cyclophosphamide treatment for systemic lupus erythematosus with severe autonomic disorders confirmed by head-up tilt table test: A case series2021

    • Author(s)
      Umeda Masataka、Kawano Hiroaki、Endo Yushiro、Takatani Ayuko、Koga Tomohiro、Ichinose Kunihiro、Nakamura Hideki、Mukaino Akihiro、Higuchi Osamu、Nakane Shunya、Maeda Takahiro、Kawakami Atsushi
    • Journal Title

      Modern Rheumatology Case Reports

      Volume: 6 Issue: 1 Pages: 47-51

    • DOI

      10.1093/mrcr/rxab027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K20905
  • [Journal Article] Inhibitory effect of HTLV-1 infection on the production of B-cell activating factors in established follicular dendritic cell-like cells.2021

    • Author(s)
      Takatani A, Nakamura H, Furukawa K, Endo Y, Umeda M, Shimizu T, Nishihata SY, Kitaoka K, Nakamura T, Kawakami A.
    • Journal Title

      Immun Inflamm Dis.

      Volume: 9 Issue: 3 Pages: 777-791

    • DOI

      10.1002/iid3.432

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08884, KAKENHI-PROJECT-21K20905
  • [Journal Article] A case of tocilizumab-refractory idiopathic multicentric Castleman's disease successfully treated with sirolimus2021

    • Author(s)
      Sumiyoshi Remi、Koga Tomohiro、Furukawa Kaori、Umeda Masataka、Yamamoto Kazuko、Mori Ryoichi、Kawakami Atsushi
    • Journal Title

      Clinical Immunology

      Volume: 233 Pages: 108887-108887

    • DOI

      10.1016/j.clim.2021.108887

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H04838, KAKENHI-PROJECT-20K20479, KAKENHI-PROJECT-20K17444, KAKENHI-PROJECT-21K20905
  • [Journal Article] CD4+ CD52lo T-cell expression contributes to the development of systemic lupus erythematosus.2018

    • Author(s)
      Umeda M, Koga T, Ichinose K(corresponding author), Igawa T, Sato T, Takatani A, Shimizu T, Fukui S, Nishino A, Horai Y, Hirai Y, Kawashiri SY, Iwamoto N, Aramaki T, Tamai M, Nakamura H, Yamamoto K, Abiru N, Origuchi T, Ueki Y, Kawakami A.
    • Journal Title

      Clin Immunol.

      Volume: 187 Pages: 50-57

    • DOI

      10.1016/j.clim.2017.10.004

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09977, KAKENHI-PROJECT-17K16210, KAKENHI-PROJECT-16K19604, KAKENHI-PROJECT-16K19605, KAKENHI-PROJECT-16H06276
  • [Presentation] ゲノム解析時代における不明熱診療に関する記述的研究2023

    • Author(s)
      梅田雅孝, 古賀智裕, 前田隆浩, 有吉紅也, 川上 純
    • Organizer
      九州リウマチ学会
    • Data Source
      KAKENHI-PROJECT-21K20905
  • [Presentation] 尿細管上皮細胞におけるADAM9はTGF-β 1活性化を介してループス腎炎の繊維化に関与する2021

    • Author(s)
      梅田雅孝, George C. Tsokos
    • Organizer
      第49回日本臨床免疫学会総会
    • Data Source
      KAKENHI-PROJECT-21K20905
  • [Presentation] Hypoxia Promotes the Expression of ADAM9 by Tubular Epithelial Cells Which Enhances TGF-β1 Activation and Promotes Tissue Fibrosis in Lupus Nephritis2021

    • Author(s)
      Masataka Umeda, Abhigyan Satyam, Nobuya Yoshida, Rhea Bhargava, Ryo Hisada, Simin Jamaly, Caroline Owen and George Tsokos
    • Organizer
      American College of Rheumatology Convergence 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20905
  • [Presentation] The CD4+CD52low T cell Contributes to the Development of Systemic Lupus Erythematosus through the CCR8/TARC Pathway2017

    • Author(s)
      Umeda M, Koga T, Ichinose K, Igawa T, Kurushima S, Takatani A, Shimizu T, Fukui S, Nishino A, Horai Y, Kawashiri S, Iwamoto N, Hirai Y, Tamai M, Nakamura H, Origuchi T, Kawakami A
    • Organizer
      Japan college of Rheumatology International Concurrent Workshop
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19604
  • [Presentation] The CD4+CD52low Tcell contributes to Disease Activity and Autoantibody Production in Systemic Lupus Erythematosus2016

    • Author(s)
      M. Umeda, T. Koga, K. Ichinose, T. Michitsuji, T. Shimizu, S. Fukui, A. Nishino, Y. Nakashima, T. Suzuki, Y. Horai, Y. Hirai, S.-Y. Kawashiri, N. Iwamoto, T. Aramaki, M. Tamai , H. Nakamura , T. Origuchi , Y. Ueki , A. Kawakami
    • Organizer
      第60回日本リウマチ学会総会・学術集会
    • Place of Presentation
      パシフィコ横浜 神奈川県横浜市
    • Data Source
      KAKENHI-PROJECT-16K19604
  • [Presentation] The CD4+CD52low T Cell Contributes to the Development of Systemic Lupus Erythematosus through the CCR8/TARC Pathway2016

    • Author(s)
      T. Sato, M. Umeda, T. Koga, K. Ichinose, T. Igawa, S. Kurushima, T. Shimizu, S. Fukui, A. Nishino, Y. Horai, Y. Hirai, S.-Y. Kawashiri, N. Iwamoto, T. Aramaki, M. Tamai, H. Nakamura, T. Origuchi, Y. Ueki, A. Kawakami
    • Organizer
      2016アメリカリウマチ学会
    • Place of Presentation
      アメリカ ワシントンDC
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19604
  • 1.  KOGA Tomohiro (90537284)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 2.  ICHINOSE Kunihiro (60437895)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 3.  辻 良香 (10866297)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  川上 茂 (20322307)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  井 隆司 (30733448)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  大庭 伸介 (20466733)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  黒嶋 伸一郎 (40443915)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  住田 吉慶 (50456654)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  松本 拡高 (90782045)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  IWAMOTO Naoki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 11.  MIGITA Kiyoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  NAKAMURA Hideki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  MORI Ryoichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  川上 純
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 15.  遠藤 友志郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  清水 俊匡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  高谷 亜由子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  寳來 吉朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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