Uojima Haruki 魚嶋晴紀

Researcher Number	20752869
Other IDs
Affiliation (Current)	2025: 北里大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 国立研究開発法人国立国際医療研究センター, 肝炎・免疫研究センター, 上級研究員 2021 – 2023: 北里大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator ウレアーゼ / Streptococcus 属菌 / Dysbiosis / 肝性脳症 / 腸内細菌叢 / 肝硬変 / Streptococcus salivariu Except Principal Investigator アルコール性肝障害 / 抗血小板抗体 / CD8陽性T細胞 … More / 免疫 / 肝癌 / 分子標的治療 / IKK / β-catenin / CD8+T細胞 / 抗 PD-L1抗体治療 / バイオマーカー / 免疫チェックポイント阻害剤 / 肝細胞癌 Less

アルコール性肝障害に伴う血小板減少に関する抗血小板抗体の病因的意義の解明
- Principal Investigator
  
  日高央
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kitasato University
新規口腔細菌による肝性脳症の増悪メカニズムの解明Principal Investigator
- Principal Investigator
  
  魚嶋晴紀
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  National Center for Global Health and Medicine
Examination of immunotherapy improvement through CD8+ T cell induction of refractory hepatocellular carcinoma and, construction of biomarkers.
- Principal Investigator
  
  Chuma Makoto
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yokohama City University

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] Metabolic Dysfunction-Associated Fatty Liver Disease on Distinct Microbial Communities at the Bacterial Phylum Level2023
- Author(s)
  Uojima Haruki、Sakaguchi Yoshihiko、Gotoh Kazuyoshi、Satoh Takashi、Hidaka Hisashi、Take Akira、Horio Kazue、Hayashi Shunji、Kusano Chika
- Journal Title
  
  Digestive Diseases
  
  Volume: 42 Issue: 1 Pages: 61-69
- DOI
  10.1159/000534284
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15083, KAKENHI-PROJECT-22K07074
[Journal Article] Impact of liver fibrosis on the relative abundance of a urease‐positive <i>Streptococcus salivarius</i> group from saliva in patients with chronic liver disease2023
- Author(s)
  Tak Akira、Uojima Haruki、Sakaguchi Yoshihiko、Gotoh Kazuyoshi、Satoh Takashi、Hidaka Hisashi、Horio Kazue、Mizokami Masashi、Hayashi Shunji、Kusano Chika
- Journal Title
  
  Hepatology Research
  
  Volume: 53 Issue: 10 Pages: 998-1007
- DOI
  10.1111/hepr.13930
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15083, KAKENHI-PROJECT-22K07074
[Journal Article] Impact of psoas muscle index assessed by a simple measurement method on tolerability and duration of continued treatment with sorafenib in hepatocellular carcinoma patients2022
- Author(s)
  Ogushi Katsuaki、Chuma Makoto、Numata Kazushi、Nozaki Akito、Moriya Satoshi、Uojima Haruki、Kondo Masaki、Morimoto Manabu、Maeda Shin
- Journal Title
  
  European Journal of Gastroenterology & Hepatology
  
  Volume: Publish Ahead of Print Issue: 7 Pages: 1-1
- DOI
  10.1097/meg.0000000000002346
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08425, KAKENHI-PROJECT-21K07899
[Journal Article] The change rate in serum nitric oxide may affect lenvatinib therapy in hepatocellular carcinoma.2022
- Author(s)
  Kawamura A, Uojima H, Chuma M, Shao X, Hidaka H, Nakazawa T, Take A, Sakaguchi Y, Numata K, Kako M, Nozaki A, Azuma S, Horio K, Kusano C, Atsuda K
- Journal Title
  
  BMC Cancer
  
  Volume: 22 Issue: 1 Pages: 912-921
- DOI
  10.1186/s12885-022-10002-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07899, KAKENHI-PROJECT-22K07074
[Journal Article] A prospective observational cohort study of lenvatinib as initial treatment in patients with BCLC-defined stage B hepatocellular carcinoma2022
- Author(s)
  Kobayashi S, Fukushima T, Ueno M, Moriya S, Chuma M, Numata K, Tsuruya K, Hirose S, Kagawa T, Hattori N, Watanabe T, Matsunaga K, Suzuki M, Uojima H, Hidaka H, Kusano C, Suzuki M, Morimoto M.
- Journal Title
  
  BMC Cancer
  
  Volume: 22 Issue: 1 Pages: 517-517
- DOI
  10.1186/s12885-022-09625-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07899
[Journal Article] Identification of CT Values That Could Be Predictive of Necrosis (N-CTav) in Hepatocellular Carcinoma after Lenvatinib Treatment2022
- Author(s)
  Makoto Chuma, Hideki Yokoo, Atsushi Hiraoka, Kazuhiko Ueda, et al.
- Journal Title
  
  Current Oncology
  
  Volume: - Issue: 5 Pages: 3259-3271
- DOI
  10.3390/curroncol29050266
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07899
[Journal Article] Safety and efficacy of atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma in early clinical practice: A multicenter analysis2021
- Author(s)
  Chuma Makoto、Hattori Nobuhiro、Watanabe Tsunamasa、Maeda Shin
- Journal Title
  
  Hepatology Research
  
  Volume: 52 Issue: 3 Pages: 269-280
- DOI
  10.1111/hepr.13732
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08451, KAKENHI-PROJECT-21K07899
[Journal Article] Analysis of efficacy of lenvatinib treatment in highly advanced hepatocellular carcinoma with tumor thrombus in the main trunk of the portal vein or tumor with more than 50% liver occupation: A multicenter analysis.2021
- Author(s)
  1.Chuma M, Uojima H, Hiraoka A, et al.
- Journal Title
  
  Hepatology Research
  
  Volume: 51 Issue: 2 Pages: 201-215
- DOI
  10.1111/hepr.13592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07899
[Presentation] 肝線維化進展が口腔内常在菌Streptococcus属菌のウレアーゼ活性に与える影響に関する検討2023
- Author(s)
  魚嶋晴紀
- Organizer
  第59回日本肝臓学会
- Data Source
  KAKENHI-PROJECT-23K15083
[Presentation] Safety and efficacy of atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma in early clinical practice: A multicenter analysis.2022
- Author(s)
  Chuma M, Uojima H, Hattori N, Arase Y, Fukushima T, Hirose S, Hidaka H, Morimoto M, Numata K, Kagawa T, Maeda S
- Organizer
  30th. United European Gastroenterology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07899
[Presentation] Identification of CT Values That Could Be Predictive of Necrosis (N-CTav) in Hepatocellular Carcinoma after Lenvatinib Treatment2022
- Author(s)
  Chuma M, Yokoo H, Hiraoka A, Ueda K, Tsuji K, Shimada N, Uojima H, Kobayashi S, Hattori N, Okubo T, Atsukawa M, Ishikawa T, Toyoda H, Tada T, Saito Y, Hidaka H, Morimoto M, Numata K, Kagawa T, Sakamoto M, Kumada T
- Organizer
  30th. United European Gastroenterology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07899
[Presentation] 切除不能肝細胞癌におけるAtezolizumab+Bevacizumabの安全性、有効性に関する多施設共同研究2022
- Author(s)
  中馬誠, 魚嶋晴紀, 福島泰斗
- Organizer
  第58回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-21K07899
[Presentation] 進行肝癌に対するAtezolizumab+Bevacizumabの初期治療成績2021
- Author(s)
  中馬誠, 魚嶋晴紀, 服部伸洋
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-21K07899

1. Chuma Makoto (30360910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. 前田愼 (40415956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 日高央 (30265607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 後藤和義 (20626593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 朝倉崇文 (30596466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 武晃 (30818399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 阪口義彦 (70403491)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 佐藤隆司 (90407114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. WATANABE Tsunamasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 近藤正晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Uojima Haruki 魚嶋 晴紀

Research Projects

Research Products

Co-Researchers

アルコール性肝障害に伴う血小板減少に関する抗血小板抗体の病因的意義の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新規口腔細菌による肝性脳症の増悪メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Examination of immunotherapy improvement through CD8+ T cell induction of refractory hepatocellular carcinoma and, construction of biomarkers.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Metabolic Dysfunction-Associated Fatty Liver Disease on Distinct Microbial Communities at the Bacterial Phylum Level2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of liver fibrosis on the relative abundance of a urease‐positive <i>Streptococcus salivarius</i> group from saliva in patients with chronic liver disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of psoas muscle index assessed by a simple measurement method on tolerability and duration of continued treatment with sorafenib in hepatocellular carcinoma patients2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The change rate in serum nitric oxide may affect lenvatinib therapy in hepatocellular carcinoma.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A prospective observational cohort study of lenvatinib as initial treatment in patients with BCLC-defined stage B hepatocellular carcinoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of CT Values That Could Be Predictive of Necrosis (N-CTav) in Hepatocellular Carcinoma after Lenvatinib Treatment2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Safety and efficacy of atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma in early clinical practice: A multicenter analysis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of efficacy of lenvatinib treatment in highly advanced hepatocellular carcinoma with tumor thrombus in the main trunk of the portal vein or tumor with more than 50% liver occupation: A multicenter analysis.2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 肝線維化進展が口腔内常在菌Streptococcus属菌のウレアーゼ活性に与える影響に関する検討2023

Author(s)

Organizer

Data Source

[Presentation] Safety and efficacy of atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma in early clinical practice: A multicenter analysis.2022

Author(s)

Organizer

Data Source

[Presentation] Identification of CT Values That Could Be Predictive of Necrosis (N-CTav) in Hepatocellular Carcinoma after Lenvatinib Treatment2022

Author(s)

Organizer

Data Source

[Presentation] 切除不能肝細胞癌におけるAtezolizumab+Bevacizumabの安全性、有効性に関する多施設共同研究2022

Author(s)

Organizer

Data Source

[Presentation] 進行肝癌に対するAtezolizumab+Bevacizumabの初期治療成績2021

Author(s)

Uojima Haruki 魚嶋晴紀