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Uojima Haruki  魚嶋 晴紀

ORCIDConnect your ORCID iD *help
Researcher Number 20752869
Other IDs
Affiliation (Current) 2025: 北里大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2023 – 2024: 国立研究開発法人国立国際医療研究センター, 肝炎・免疫研究センター, 上級研究員
2021 – 2023: 北里大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Basic Section 53010:Gastroenterology-related
Keywords
Principal Investigator
ウレアーゼ / Streptococcus 属菌 / Dysbiosis / 肝性脳症 / 腸内細菌叢 / 肝硬変 / Streptococcus salivariu
Except Principal Investigator
アルコール性肝障害 / 抗血小板抗体 / CD8陽性T細胞 … More / 免疫 / 肝癌 / 分子標的治療 / IKK / β-catenin / CD8+T細胞 / 抗 PD-L1抗体治療 / バイオマーカー / 免疫チェックポイント阻害剤 / 肝細胞癌 Less
  • Research Projects

    (3 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (10 People)
  •  アルコール性肝障害に伴う血小板減少に関する抗血小板抗体の病因的意義の解明

    • Principal Investigator
      日高 央
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kitasato University
  •  新規口腔細菌による肝性脳症の増悪メカニズムの解明Principal Investigator

    • Principal Investigator
      魚嶋 晴紀
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      National Center for Global Health and Medicine
  •  Examination of immunotherapy improvement through CD8+ T cell induction of refractory hepatocellular carcinoma and, construction of biomarkers.

    • Principal Investigator
      Chuma Makoto
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Yokohama City University

All 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] Metabolic Dysfunction-Associated Fatty Liver Disease on Distinct Microbial Communities at the Bacterial Phylum Level2023

    • Author(s)
      Uojima Haruki、Sakaguchi Yoshihiko、Gotoh Kazuyoshi、Satoh Takashi、Hidaka Hisashi、Take Akira、Horio Kazue、Hayashi Shunji、Kusano Chika
    • Journal Title

      Digestive Diseases

      Volume: 42 Issue: 1 Pages: 61-69

    • DOI

      10.1159/000534284

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K15083, KAKENHI-PROJECT-22K07074
  • [Journal Article] Impact of liver fibrosis on the relative abundance of a urease‐positive <i>Streptococcus salivarius</i> group from saliva in patients with chronic liver disease2023

    • Author(s)
      Tak Akira、Uojima Haruki、Sakaguchi Yoshihiko、Gotoh Kazuyoshi、Satoh Takashi、Hidaka Hisashi、Horio Kazue、Mizokami Masashi、Hayashi Shunji、Kusano Chika
    • Journal Title

      Hepatology Research

      Volume: 53 Issue: 10 Pages: 998-1007

    • DOI

      10.1111/hepr.13930

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K15083, KAKENHI-PROJECT-22K07074
  • [Journal Article] Impact of psoas muscle index assessed by a simple measurement method on tolerability and duration of continued treatment with sorafenib in hepatocellular carcinoma patients2022

    • Author(s)
      Ogushi Katsuaki、Chuma Makoto、Numata Kazushi、Nozaki Akito、Moriya Satoshi、Uojima Haruki、Kondo Masaki、Morimoto Manabu、Maeda Shin
    • Journal Title

      European Journal of Gastroenterology &amp; Hepatology

      Volume: Publish Ahead of Print Issue: 7 Pages: 1-1

    • DOI

      10.1097/meg.0000000000002346

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08425, KAKENHI-PROJECT-21K07899
  • [Journal Article] The change rate in serum nitric oxide may affect lenvatinib therapy in hepatocellular carcinoma.2022

    • Author(s)
      Kawamura A, Uojima H, Chuma M, Shao X, Hidaka H, Nakazawa T, Take A, Sakaguchi Y, Numata K, Kako M, Nozaki A, Azuma S, Horio K, Kusano C, Atsuda K
    • Journal Title

      BMC Cancer

      Volume: 22 Issue: 1 Pages: 912-921

    • DOI

      10.1186/s12885-022-10002-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07899, KAKENHI-PROJECT-22K07074
  • [Journal Article] A prospective observational cohort study of lenvatinib as initial treatment in patients with BCLC-defined stage B hepatocellular carcinoma2022

    • Author(s)
      Kobayashi S, Fukushima T, Ueno M, Moriya S, Chuma M, Numata K, Tsuruya K, Hirose S, Kagawa T, Hattori N, Watanabe T, Matsunaga K, Suzuki M, Uojima H, Hidaka H, Kusano C, Suzuki M, Morimoto M.
    • Journal Title

      BMC Cancer

      Volume: 22 Issue: 1 Pages: 517-517

    • DOI

      10.1186/s12885-022-09625-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Journal Article] Identification of CT Values That Could Be Predictive of Necrosis (N-CTav) in Hepatocellular Carcinoma after Lenvatinib Treatment2022

    • Author(s)
      Makoto Chuma, Hideki Yokoo, Atsushi Hiraoka, Kazuhiko Ueda, et al.
    • Journal Title

      Current Oncology

      Volume: - Issue: 5 Pages: 3259-3271

    • DOI

      10.3390/curroncol29050266

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Journal Article] Safety and efficacy of atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma in early clinical practice: A multicenter analysis2021

    • Author(s)
      Chuma Makoto、Hattori Nobuhiro、Watanabe Tsunamasa、Maeda Shin
    • Journal Title

      Hepatology Research

      Volume: 52 Issue: 3 Pages: 269-280

    • DOI

      10.1111/hepr.13732

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08451, KAKENHI-PROJECT-21K07899
  • [Journal Article] Analysis of efficacy of lenvatinib treatment in highly advanced hepatocellular carcinoma with tumor thrombus in the main trunk of the portal vein or tumor with more than 50% liver occupation: A multicenter analysis.2021

    • Author(s)
      1.Chuma M, Uojima H, Hiraoka A, et al.
    • Journal Title

      Hepatology Research

      Volume: 51 Issue: 2 Pages: 201-215

    • DOI

      10.1111/hepr.13592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Presentation] 肝線維化進展が口腔内常在菌Streptococcus属菌のウレアーゼ活性に与える影響に関する検討2023

    • Author(s)
      魚嶋晴紀
    • Organizer
      第59回日本肝臓学会
    • Data Source
      KAKENHI-PROJECT-23K15083
  • [Presentation] Safety and efficacy of atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma in early clinical practice: A multicenter analysis.2022

    • Author(s)
      Chuma M, Uojima H, Hattori N, Arase Y, Fukushima T, Hirose S, Hidaka H, Morimoto M, Numata K, Kagawa T, Maeda S
    • Organizer
      30th. United European Gastroenterology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Presentation] Identification of CT Values That Could Be Predictive of Necrosis (N-CTav) in Hepatocellular Carcinoma after Lenvatinib Treatment2022

    • Author(s)
      Chuma M, Yokoo H, Hiraoka A, Ueda K, Tsuji K, Shimada N, Uojima H, Kobayashi S, Hattori N, Okubo T, Atsukawa M, Ishikawa T, Toyoda H, Tada T, Saito Y, Hidaka H, Morimoto M, Numata K, Kagawa T, Sakamoto M, Kumada T
    • Organizer
      30th. United European Gastroenterology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Presentation] 切除不能肝細胞癌におけるAtezolizumab+Bevacizumabの安全性、有効性に関する多施設共同研究2022

    • Author(s)
      中馬誠, 魚嶋晴紀, 福島泰斗
    • Organizer
      第58回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Presentation] 進行肝癌に対するAtezolizumab+Bevacizumabの初期治療成績2021

    • Author(s)
      中馬誠, 魚嶋晴紀, 服部伸洋
    • Organizer
      第57回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-21K07899
  • 1.  Chuma Makoto (30360910)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 2.  前田 愼 (40415956)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  日高 央 (30265607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  後藤 和義 (20626593)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  朝倉 崇文 (30596466)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  武 晃 (30818399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  阪口 義彦 (70403491)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  佐藤 隆司 (90407114)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  WATANABE Tsunamasa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  近藤 正晃
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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