Araiso Yuhei 荒磯裕平

Researcher Number	20753726
Other IDs
Affiliation (Current)	2025: 金沢大学, 保健学系, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 金沢大学, 保健学系, 准教授 2020 – 2022: 金沢大学, 保健学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 28040:Nanobioscience-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields Except Principal Investigator Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 52010:General internal medicine-related / Basic Section 44010:Cell biology-related
Keywords	Principal Investigator 高速原子間力顕微鏡 / 膜タンパク質複合体 / TOM複合体 / タンパク質輸送 / ミトコンドリア / 膜タンパク質 / GFP / クライオ電子顕微鏡 / タンパク質複合体 / 膜透過装置 / 前駆体タンパク質 … More Except Principal Investigator … More 中性子反射率法 / グラム陰性菌 / TOM複合体 / BAM複合体 / タンパク質輸送装置 / 分子イメージング / ミオグロビン / タンパク質輸送 / ミトコンドリア / 筋細胞 / VTE / 静脈血栓塞栓症 / パネル検査 / Liposome flotation assay / 高速原子力間顕微鏡 / ノックアウトゼブラフィッシュ / NGSパネル検査 / プロテインS（PS）欠乏症 / プロテインC(PC)欠乏症 / アンチトロンビン（AT）欠乏症 / 遺伝性血栓症 / 転写調節因子E2F / Rbがん抑制タンパク / サイクリン / プロテインホスファターゼ / IER2タンパク / Rbがん抑制遺伝子 / 細胞運動 / 細胞周期 / E2F転写調節因子 / RBがん抑制遺伝子 / IERタンパク / PP2Aアダプタータンパク / Protein phosphatase 2A Less

Mechanisms of cellular functional modification induced by unconventional proteins transported to mitochondria in myocyte
- Principal Investigator
  
  増田和実
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kanazawa University
Analysis of super complex of protein translocators using multiple biophysical approaches
- Principal Investigator
  
  塩田拓也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  University of Miyazaki
Elucidation of the precise protein transport mechanism regulated by the "heterogeneous" translocase of the outer mitochondrial membranePrincipal Investigator
- Principal Investigator
  
  荒磯裕平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 28040:Nanobioscience-related
- Research Institution
  Kanazawa University
遺伝性血栓症の病因（オミックス解析）と病態の解明
- Principal Investigator
  
  森下英理子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kanazawa University
タンパク質複合体の動きをリアルタイムで追跡するGFPトラッキング法の確立Principal Investigator
- Principal Investigator
  
  荒磯裕平
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Kanazawa University
Regulation of signal transduction and cell growth by protein phosphatase 2A
- Principal Investigator
  
  Sakurai Hiroshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Kanazawa University
Dynamic analysis of precursor proteins passing through the translocase of the mitochondrial outer membrane complexPrincipal Investigator
- Principal Investigator
  
  Araiso Yuhei
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 28040:Nanobioscience-related
- Research Institution
  Kanazawa University

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Functional analysis of two abnormal antithrombin proteins with different intracellular kinetics2023
- Author(s)
  Imai Yuta、Nagaya Satomi、Araiso Yuhei、Meguro-Horike Makiko、Togashi Tomoki、Horike Shin-ichi、Kawasaki Hiroshi、Morishita Eriko
- Journal Title
  
  Thrombosis Research
  
  Volume: 230 Pages: 18-26
- DOI
  10.1016/j.thromres.2023.08.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06896, KAKENHI-PROJECT-22K07391, KAKENHI-PROJECT-21K19306, KAKENHI-PROJECT-22K15663, KAKENHI-PROJECT-20H03338
[Journal Article] Role of the TOM complex in Protein Import into Mitochondria: Structural Views2022
- Author(s)
  Yuhei Araiso, Kenichiro Imai, Toshiya Endo
- Journal Title
  
  Annual Review of Biochemistry
  
  Volume: 91 Issue: 1 Pages: 679-703
- DOI
  10.1146/annurev-biochem-032620-104527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02583, KAKENHI-PROJECT-20H05689, KAKENHI-PROJECT-21H03551, KAKENHI-PLANNED-20H05929
[Journal Article] Structural overview of the translocase of the mitochondrial outer membrane complex2022
- Author(s)
  Araiso Y, Imai K, Endo
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 19 Issue: 0 Pages: n/a
- DOI
  10.2142/biophysico.bppb-v19.0022
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05705, KAKENHI-PROJECT-20H02583, KAKENHI-PLANNED-20H05929, KAKENHI-PROJECT-20H05689
[Journal Article] Identification and functional analysis of three novel genetic variants resulting in premature termination codons in three unrelated patients with hereditary antithrombin deficiency2022
- Author(s)
  Imai Yuta、Nagaya Satomi、Araiso Yuhei、Meguro-Horike Makiko、Togashi Tomoki、Ohmori Kensho、Makita Yuka、Sato Eiichi、Yujiri Toshiaki、Nagamori Yuta、Horike Shin-ichi、Watanabe Atsushi、Morishita Eriko
- Journal Title
  
  International Journal of Hematology
  
  Volume: 117 Issue: 4 Pages: 523-529
- DOI
  10.1007/s12185-022-03509-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07391, KAKENHI-PROJECT-22K15663
[Journal Article] Structural snapshot of the mitochondrial protein import gate2021
- Author(s)
  Araiso Y, Imai K, Endo T
- Journal Title
  
  FEBS J
  
  Volume: - Issue: 18 Pages: 1-11
- DOI
  10.1111/febs.15661
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11543, KAKENHI-PUBLICLY-20H04912, KAKENHI-PROJECT-20H02583, KAKENHI-PROJECT-15H05705
[Presentation] アンチトロンビンノックアウトゼブラフィッシュの初期胚発生過程における血栓形成2023
- Author(s)
  今井湧太, 野田太希, 小林功, 稲津明広, 森下英理子, 荒磯裕平
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07391
[Presentation] ミトコンドリアタンパク質搬入ゲートTOM複合体の構造とダイナミクス2023
- Author(s)
  荒磯裕平、小林菜々子、Romain Amyot、九笹加菜、今井大達、川合志朋、今井賢一郎、稲津明広、古寺哲幸、遠藤斗志也
- Organizer
  令和４年度生物物理学会中部支部講演会（名古屋）
- Data Source
  KAKENHI-PROJECT-22K19268
[Presentation] ミトコンドリアタンパク質搬入ゲートTOM複合体の構造とダイナミクス2023
- Author(s)
  荒磯裕平、小林菜々子、Romain Amyot、九笹加菜、今井大達、川合志朋、今井賢一郎、稲津明広、古寺哲幸、遠藤斗志也
- Organizer
  令和４年度生物物理学会中部支部講演会（名古屋）
- Data Source
  KAKENHI-PROJECT-20H02583
[Presentation] ミトコンドリア膜透過装置TOM複合体の一分子動態解析2023
- Author(s)
  小林菜々子、九笹加菜、 Romain Amyot 、今井大達、川合志朋、今井湧太、稲津明広、今井賢一郎、古寺哲幸、遠藤斗志也、荒磯裕平
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K26507
[Presentation] Elucidating the substrate degradation mechanism of mitochondrial inner membrane AAA+ protease Yme12023
- Author(s)
  今井湧太、古寺哲幸、荒磯裕平
- Organizer
  第１回SFD国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K26507
[Presentation] HS-AFM analysis of Drp1, a dynamin-like protein that regulates mitochondrial fission2023
- Author(s)
  喜多慎太郎、上谷望花、本田知也、辻本大貴、稲津明広、古寺哲幸、荒磯裕平
- Organizer
  第１回SFD国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19268
[Presentation] ミトコンドリア分裂を制御するダイナミン様タンパク質Drp1の高速原子間力顕微鏡解析2023
- Author(s)
  喜多慎太郎、本田知也、上谷望花、辻本大貴、稲津明広、古寺哲幸、荒磯裕平
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-22K19268
[Presentation] ミトコンドリア膜透過装置TOM複合体の高速原子間力顕微鏡解析2022
- Author(s)
  小林菜々子、九笹加菜、今井大達、川合志朋、槙野愛実、稲津明広、古寺哲幸、遠藤斗志也、荒磯裕平
- Organizer
  第45回日本分子生物学会年会（千葉）
- Data Source
  KAKENHI-PROJECT-20H02583
[Presentation] 高速原子間力顕微鏡によって明らかになったミトコンドリアタンパク質搬入ゲート TOM複合体の構造とダイナミクス2022
- Author(s)
  九笹加菜、小林菜々子、今井大達、槙野愛実、稲津明広、古寺哲幸、遠藤斗志也、荒磯裕平
- Organizer
  第22回日本蛋白質科学会年会（筑波）
- Data Source
  KAKENHI-PROJECT-20H02583
[Presentation] 高速原子間力顕微鏡解析によって明らかになったミトコンドリアタンパク質搬入ゲートTOM複合体の構造とダイナミクス2022
- Author(s)
  九笹加菜、小林菜々子、今井大達、槙野愛実、稲津明広、古寺哲幸、遠藤斗志也、荒磯裕平
- Organizer
  第22回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02583
[Presentation] 2つの異常バリアントから生成される異常アンチトロンビンタンパクの動態解析2022
- Author(s)
  今井湧太、長屋聡美、荒磯裕平、冨樫朋貴、大森健聖、牧田友香、伊勢美樹子、森下英理子
- Organizer
  第44回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07391
[Presentation] High-speed atomic force microscopy analysis of the mitochondrial import gate TOM complex2022
- Author(s)
  荒磯裕平、九笹加菜、小林菜々子、今井大達、槙野愛実、稲津明広、古寺哲幸、遠藤斗志也
- Organizer
  第60回日本生物物理学会年会（函館）
- Data Source
  KAKENHI-PROJECT-20H02583
[Presentation] ミトコンドリアタンパク質搬入ゲートTOM複合体の構造とダイナミクス2022
- Author(s)
  荒磯裕平
- Organizer
  日本生化学会北陸支部会　第40回大会（富山）
- Invited
- Data Source
  KAKENHI-PROJECT-20H02583
[Presentation] High-Speed atomic force microscopy analysis of the mitochondrial protein import gate TOM complex2021
- Author(s)
  Kana Kuzasa, Hirotatsu Imai, Noriyuki Kodera, Akihiro Inazu, Toshiya Endo, Yuhei Araiso
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H02583
[Presentation] Structural analysis of the mitochondrial protein import gate by near-atomic resolution snapshot and nanoscale video imaging2021
- Author(s)
  Yuhei Araiso, Akihisa Tsutsumi, Kenichiro Imai, Takuya Shiota, Hirotatsu Imai, Kana Kuzasa, Noriyuki Kodera, Masahide Kikkawa, Toshiya Endo
- Organizer
  第44回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02583
[Presentation] 高速原子間力顕微鏡を用いたミトコンドリアタンパク質搬入ゲートTOM複合体の動的構造解析2021
- Author(s)
  九笹加菜、今井大達、古寺哲幸、稲津明広、遠藤斗志也、荒磯裕平
- Organizer
  日本生化学会北陸支部第39回大会
- Data Source
  KAKENHI-PROJECT-20H02583
[Presentation] Structure of the mitochondrial protein import gate reveals distinct protein path2020
- Author(s)
  荒磯裕平
- Organizer
  第２０回日本蛋白質科学会年会若手奨励賞シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H02583
[Presentation] ミトコンドリアへのタンパク質搬入ゲートTOM複合体の構造と機能2020
- Author(s)
  荒磯裕平
- Organizer
  日本生体エネルギー研究会第４６回討論会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02583

1. Sakurai Hiroshi (00225848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 森下英理子 (50251921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 小原收 (20370926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 増田和実 (50323283)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 芝口翼 (40785953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 新井敏 (70454056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 塩田拓也 (20819304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 宮崎亮次 (30827564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 青木英莉子 (80822874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. IMAI Kenichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. HORIKE Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Araiso Yuhei 荒磯 裕平

Research Projects

Research Products

Co-Researchers

Mechanisms of cellular functional modification induced by unconventional proteins transported to mitochondria in myocyte

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of super complex of protein translocators using multiple biophysical approaches

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the precise protein transport mechanism regulated by the "heterogeneous" translocase of the outer mitochondrial membranePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

遺伝性血栓症の病因（オミックス解析）と病態の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

タンパク質複合体の動きをリアルタイムで追跡するGFPトラッキング法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of signal transduction and cell growth by protein phosphatase 2A

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Dynamic analysis of precursor proteins passing through the translocase of the mitochondrial outer membrane complexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Functional analysis of two abnormal antithrombin proteins with different intracellular kinetics2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of the TOM complex in Protein Import into Mitochondria: Structural Views2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural overview of the translocase of the mitochondrial outer membrane complex2022

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Identification and functional analysis of three novel genetic variants resulting in premature termination codons in three unrelated patients with hereditary antithrombin deficiency2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural snapshot of the mitochondrial protein import gate2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] アンチトロンビンノックアウトゼブラフィッシュの初期胚発生過程における血栓形成2023

Author(s)

Organizer

Data Source

[Presentation] ミトコンドリアタンパク質搬入ゲートTOM複合体の構造とダイナミクス2023

Author(s)

Organizer

Araiso Yuhei 荒磯裕平