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Yamamoto Takeshi  山本 毅士

ORCIDConnect your ORCID iD *help
Researcher Number 20756994
Other IDs
Affiliation (Current) 2025: 大阪大学, 大学院医学系研究科, 特任助教(常勤)
Affiliation (based on the past Project Information) *help 2022 – 2024: 大阪大学, 大学院医学系研究科, 特任助教(常勤)
2021: 大阪大学, 医学部附属病院, 医員
2015 – 2017: 大阪大学, 医学部附属病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 53040:Nephrology-related / Kidney internal medicine
Except Principal Investigator
Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 53040:Nephrology-related
Keywords
Principal Investigator
オートファジー / 脂肪毒性 / リソソーム / 尿細管 / TFEB / 肥満関連尿細管症 / フェロトーシス / 高齢者 / 腎老化 / cGAS-STING … More / DNA damage / 3次リンパ組織 / cellular senescence / autophagy / kidney aging / 腎障害 / がん / DNA損傷 / p53 / ミトコンドリア / 脂肪滴 / オートファジーフラックス / エベロリムス / クロロキン / Rubicon / 老化 / 近位尿細管 / フラックス … More
Except Principal Investigator
老化細胞 / オートファジー / 糖尿病関連腎臓病 / AKI脆弱性 Less
  • Research Projects

    (6 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (4 People)
  •  Seeds Search for Preventing AKI in the Elderly Focusing on AKI Vulnerability

    • Principal Investigator
      猪阪 善隆
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Osaka University
  •  Exploration of aging tubule-inducing factors and their pathophysiology for the development of therapeutic agents for diabetic kidney disease

    • Principal Investigator
      猪阪 善隆
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Osaka University
  •  Elucidating the pathogenesis of obesity-related proximal tubulopathy and searching for the therapeutic agents: focus on the lysosome-ferroptosis axisPrincipal Investigator

    • Principal Investigator
      山本 毅士
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Osaka University
  •  Unraveling the cooperative action of p53 and autophagy against kidney agingPrincipal Investigator

    • Principal Investigator
      Yamamoto Takeshi
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Osaka University
  •  脂肪毒性抑制機構としての脂肪滴-オートファジー相互作用の解明と治療への応用Principal Investigator

    • Principal Investigator
      山本 毅士
    • Project Period (FY)
      2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Osaka University
  •  Strategies aimed at modulating autophagy for treating kidney diseasesPrincipal Investigator

    • Principal Investigator
      Yamamoto Takeshi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Kidney internal medicine
    • Research Institution
      Osaka University

All 2021 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] 加齢によるオートファジー活性の変化がミトコンドリア機能低下を介して腎老化を引き起こす2016

    • Author(s)
      山本毅士
    • Journal Title

      日本腎臓学会誌

      Volume: 58 Pages: 1238-1242

    • Data Source
      KAKENHI-PROJECT-15H06371
  • [Journal Article] Time-dependent dysregulation of autophagy: Implications in aging and mitochondrial homeostasis in the kidney proximal tubule.2016

    • Author(s)
      Yamamoto T, Takabatake Y, Kimura T, Takahashi A, Namba T, Matsuda J, Minami S, Kaimori JY, Matsui I, Kitamura H, Matsusaka T, Niimura F, Yanagita M, Isaka Y, Rakugi H.
    • Journal Title

      Autophagy

      Volume: 12 Issue: 5 Pages: 801-13

    • DOI

      10.1080/15548627.2016.1159376

    • NAID

      40021034920

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H06371
  • [Presentation] Cooperative action of p53 and autophagy delays kidney aging by suppressing DNA damage and the senescence-associated secretory phenotype2021

    • Author(s)
      Satoshi Minami, Takeshi Yamamoto, Yoshitaka Isaka, Tamotsu Yoshimori
    • Organizer
      The 6th International Cell Senescence Association(ICSA) Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K16163
  • [Presentation] イコサペント酸エチルは高脂肪食によるオートファジーフラックス障害を解除し腎脂肪毒性を軽減する2017

    • Author(s)
      山本 毅士, 高畠 義嗣, 南 聡, 高橋 篤史, 難波 倫子, 酒井 晋介, 藤村 龍太, 松田 潤, 木村 友則, 新村 文男, 松阪 泰二, 猪阪 善隆
    • Organizer
      日本腎臓学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2017-05-26
    • Data Source
      KAKENHI-PROJECT-17K16083
  • [Presentation] Time-dependent dysregulation of autophagy: Implications in aging and mitochondrial homeostasis in the kidney proximal tubule2016

    • Author(s)
      山本毅士
    • Organizer
      第38回腎臓セミナー・Nexus Japan
    • Place of Presentation
      東京
    • Year and Date
      2016-08-27
    • Data Source
      KAKENHI-PROJECT-15H06371
  • [Presentation] 加齢によるオートファジー活性の変化がミトコンドリア機能低下を介して腎老化を引き起こす2015

    • Author(s)
      山本毅士
    • Organizer
      第6回分子腎臓フォーラム
    • Place of Presentation
      大阪
    • Year and Date
      2015-09-05
    • Data Source
      KAKENHI-PROJECT-15H06371
  • 1.  猪阪 善隆 (00379166)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  南 聡 (00791592)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  酒井 晋介 (60817360)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  松井 翔 (70974286)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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