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Sakaguchi Shoichi  坂口 翔一

Researcher Number 20815279
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-3650-1221
Affiliation (Current) 2025: 大阪医科薬科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2021 – 2024: 大阪医科薬科大学, 医学部, 助教
2020: 大阪医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 42020:Veterinary medical science-related
Except Principal Investigator
Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 57020:Oral pathobiological science-related / Basic Section 55020:Digestive surgery-related / Basic Section 58030:Hygiene and public health-related: excluding laboratory approach / Basic Section 45020:Evolutionary biology-related
Keywords
Principal Investigator
RNAウイルス / ウイルス / ネコモルビリウイルス / 尿細管間質性腎炎 / 腎臓 / ネコ / RNA / RdRp / Defective Interfering / 不完全ゲノム / RNA依存性RNAポリメラーゼ / 人獣共通感染症 / リバースジェネティクス … More
Except Principal Investigator
… More 胃内細菌叢 / 胃癌 / 口腔内細菌叢 / シミュレーションモデル / 遺伝子変異 / 遺伝子変異予測モデル / 単クローン株 / オルソレオウイルス / オルガノイド / コウモリ / IgA / 口腔細菌叢 / 多様性 / 細菌叢 / 胃切除後障害 / 16SリボソームRNA遺伝子 / 次世代シークエンサー解析 / メタゲノム解析 / 術後体重減少 / 幽門側胃切除術 / 幽門側胃切除 / 細菌叢形成機序 / コホート研究 / 乳幼児 / 妊産婦 / 胎盤 / 新規機能遺伝子 / レトロウイルス / 細胞融合 / 受容体 / 進化モデル / 膜融合 / 膜タンパク質 / レトロトランスポゾン / ゲノム進化 / 哺乳類 / 新規遺伝子 / 比較ゲノム / 分子進化 / 内在性レトロウイルス Less
  • Research Projects

    (7 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (18 People)
  •  オルガノイド・オン・チップを用いたコウモリ由来ウイルス発生予測モデルの開発

    • Principal Investigator
      大松 勉
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Immunoglobulin A and the oral microbiota in Gastric Cancer Patients

    • Principal Investigator
      小越 菜保子
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Osaka Medical and Pharmaceutical University
  •  胃切除後障害の改善に向けた網羅的細菌叢変化の検討

    • Principal Investigator
      今井 義朗
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Osaka Medical and Pharmaceutical University
  •  The role of incomplete viral RNA in persistent feline morbillivirus infection.Principal Investigator

    • Principal Investigator
      Sakaguchi Shoichi
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Osaka Medical and Pharmaceutical University
  •  Studies on the mechanism of oral microbiome formation via microbiome analysis of pregnant women and their infants

    • Principal Investigator
      Hayashi Emi
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
    • Research Institution
      Osaka Medical and Pharmaceutical University
  •  Construction of molecular evolution model for genes derived from endogenous retroviruses

    • Principal Investigator
      Nakagawa So
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 45020:Evolutionary biology-related
    • Research Institution
      Tokai University
  •  Establishment of a molecular clone of feline morbillivirus by reverse genetics system and elucidation of its intracellular entry mechanismPrincipal Investigator

    • Principal Investigator
      Sakaguchi Shoichi
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Osaka Medical and Pharmaceutical University

All 2025 2024 2023 2022 2021 2020

All Journal Article Presentation

  • [Journal Article] NeoRdRp2 with improved seed data, annotations, and scoring2024

    • Author(s)
      Sakaguchi Shoichi、Nakano Takashi、Nakagawa So
    • Journal Title

      Frontiers in Virology

      Volume: 4

    • DOI

      10.3389/fviro.2024.1378695

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K14999
  • [Journal Article] Exploring the hidden world of RNA viruses with a transformer-based tool2024

    • Author(s)
      Nakagawa So、Sakaguchi Shoichi
    • Journal Title

      Patterns

      Volume: 5 Issue: 11 Pages: 101095-101095

    • DOI

      10.1016/j.patter.2024.101095

    • Open Access
    • Data Source
      KAKENHI-PROJECT-22K14999
  • [Journal Article] Changes in salivary microbiota due to gastric cancer resection and its relation to gastric fluid microbiota2023

    • Author(s)
      Komori Eri、Kato-Kogoe Nahoko、Imai Yoshiro、Sakaguchi Shoichi、Taniguchi Kohei、Omori Michi、Ohmichi Mayu、Nakamura Shota、Nakano Takashi、Lee Sang-Woong、Ueno Takaaki
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 15863-15863

    • DOI

      10.1038/s41598-023-43108-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K16012, KAKENHI-PROJECT-22K08903, KAKENHI-PROJECT-23K09160
  • [Journal Article] The International Virus Bioinformatics Meeting 20232023

    • Author(s)
      Hufsky F.、Abecasis A.、Babaian A.、Beck S.、Brierley L.、Dellicour S.、Eggeling C.、Elena S.、Gieraths U.、Ha A.、Harvey W.、Jones T.、Lamkiewicz K.、Lovate G.、Lucking D.、Machyna M.、Nishimura L.、Nocke M.、Renard B.、Sakaguchi S.ら
    • Journal Title

      Viruses

      Volume: 15 Issue: 10 Pages: 2031-2031

    • DOI

      10.3390/v15102031

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K14999, KAKENHI-PROJECT-22KJ1416
  • [Journal Article] Current trends in RNA virus detection through metatranscriptome sequencing data2023

    • Author(s)
      Nakagawa So、Sakaguchi Shoichi、Ogura Atsushi、Mineta Katsuhiko、Endo Toshinori、Suzuki Yoshiyuki、Gojobori Takashi
    • Journal Title

      FEBS Open Bio

      Volume: accepted Issue: 6 Pages: 992-1000

    • DOI

      10.1002/2211-5463.13626

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21452, KAKENHI-PROJECT-22K14999
  • [Journal Article] NeoRdRp: A comprehensive dataset for identifying RNA-dependent RNA polymerase of various RNA viruses from metatranscriptomic data2022

    • Author(s)
      Sakaguchi Shoichi、Urayama Syun-ichi、Takaki Yoshihiro、Hirosuna Kensuke、Wu Hong、Suzuki Youichi、Nunoura Takuro、Nakano Takashi、Nakagawa So
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/2021.12.31.474423

    • Open Access
    • Data Source
      KAKENHI-PROJECT-20K15685
  • [Journal Article] Comparison of the gastric microbiome in Billroth I and Roux-en-Y reconstructions after distal gastrectomy2022

    • Author(s)
      Imai Yoshiro、Lee Sang-Woong、Sakaguchi Shoichi、Kato-Kogoe Nahoko、Taniguchi Kohei、Omori Michi、Tanaka Ryo、Honda Kotaro、Osumi Wataru、Nakano Takashi、Ueno Takaaki、Uchiyama Kazuhisa
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 10594-10594

    • DOI

      10.1038/s41598-022-14886-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08903, KAKENHI-PROJECT-20K09932, KAKENHI-PROJECT-20K18521
  • [Journal Article] Identification of cellular inhibitors against Chikungunya virus replication by a cDNA expression cloning combined with MinION sequencing2020

    • Author(s)
      Sakaguchi Shoichi、Suzuki Youichi、Emi Akino、Wu Hong、Nakano Takashi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 530 Issue: 4 Pages: 617-623

    • DOI

      10.1016/j.bbrc.2020.07.036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07596, KAKENHI-PROJECT-20K15685
  • [Presentation] 喫煙妊婦・過去喫煙妊婦の口腔内細菌叢のメタゲノム解析.2025

    • Author(s)
      久藤麻子、小越菜保子、坂口翔一、林江美、藤田太輔、中野隆史、大道正英、 玉置淳子.
    • Organizer
      第95回日本衛生学会学術総会.
    • Data Source
      KAKENHI-PROJECT-23K09160
  • [Presentation] 喫煙妊婦・過去喫煙妊婦の口腔内細菌叢のメタゲノム解析2025

    • Author(s)
      久藤麻子,小越菜保子,坂口翔一,林江美, 藤田太輔,中野隆史,大道正英,玉置 淳子
    • Organizer
      第95回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K10456
  • [Presentation] 包括的RNAウイルス検出のためのHMMデータセット「NeoRdRp2」を用いたメタトランスクリプトームデータ解析2024

    • Author(s)
      坂口翔一、中川草、中野隆史
    • Organizer
      第167回 日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K14999
  • [Presentation] RNA Virome analyses of metatranscriptome data using NeoRdRp2024

    • Author(s)
      Shoichi Sakaguchi
    • Organizer
      International Virus Bioinformatics Meeting 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K14999
  • [Presentation] Identification of diversified RNA viruses from various environments using NeoRdRp2024

    • Author(s)
      Shoichi Sakaguchi, So Nakagawa, Takashi Nakano
    • Organizer
      第26回日本進化学会神奈川大会
    • Data Source
      KAKENHI-PROJECT-22K14999
  • [Presentation] RNA Virus Discovery Using HMM of Large-Scale RNA-Dependent RNA Polymerase Sequence Data: NeoRdRp 2.02023

    • Author(s)
      Shoichi Sakaguchi
    • Organizer
      The International Virus Bioinformatics Meeting 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K14999
  • [Presentation] RNA依存性RNAポリメラーゼを用いたRNAウイルス叢解析パイプライン2021

    • Author(s)
      坂口翔一、呉紅、鈴木陽一、中野隆史、中川草
    • Organizer
      ウイルス学若手研究集会2021
    • Data Source
      KAKENHI-PROJECT-20K15685
  • 1.  小越 菜保子 (60509115)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 2.  植野 高章 (60252996)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  今井 義朗 (60734415)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  谷口 高平 (70779686)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 5.  Nakagawa So (70510014)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  Hayashi Emi (50445988)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  宮沢 孝幸 (80282705)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  玉置 淳子 (90326356)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  久藤 麻子 (10289605)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  中野 隆史 (00257867)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  大道 正英 (10283764)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  藤田 太輔 (90411371)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  李 相雄 (40368080)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 14.  大松 勉 (60455392)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  臼井 達哉 (80727652)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  SUZUKI Youichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  OGURA Atsushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  大森 実知
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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