Yamashiro Takahiro 山城貴弘

Researcher Number	20826614
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(薬学), 講師
Affiliation (based on the past Project Information) *help	2019 – 2024: 名古屋市立大学, 医薬学総合研究院(薬学), 助教 2021: 名古屋市立大学, 薬学研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 47060:Clinical pharmacy-related
Keywords	Principal Investigator トランスポーター / ビタミン / ピリドキシン / 相互作用 / 動物種差 / 薬物吸収 / 基質認識機構 / 薬物間相互作用 / 迅速機能評価 / 蛍光 … More / 遺伝子変異 / Leigh脳症 / BTBGD / SLC19A3 / チアミン / クロストーク / イオンチャネル / 大腸癌 / 吸収 / 小腸 / 腸管吸収 … More Except Principal Investigator トランスポーター / 創薬標的 / 薬物送達 / コリン / 神経伝達 / シナプス小胞 / モノアミン / 前立腺 / プトレシン / スペルミン / スペルミジン / ポリアミン / 高尿酸血症 / リソソーム / 痛風 / 尿酸結晶 / 尿酸 Less

新規小胞膜局在型モノアミントランスポーターの機能解析と創薬標的としての有望性評価
- Principal Investigator
  
  保嶋智也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
新規コリントランスポーター類の分子機能と生理的及び薬物動態的役割
- Principal Investigator
  
  湯浅博昭
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
Elucidation of substrate recognition mechanism of SLC19A3 to establish the molecular basis for medical applicationsPrincipal Investigator
- Principal Investigator
  
  山城貴弘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
新規ピリドキシントランスポーターとイオン輸送体の応答によるピリドキシン動態の解明Principal Investigator
- Principal Investigator
  
  山城貴弘
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
Elucidation of molecular mechanism of substrate-dependent transport function of SLC19A3 and its relevance to pathologyPrincipal Investigator
- Principal Investigator
  
  Yamashiro Takahiro
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
Elucidation of molecular mechanism that triggers onset of gout from hyperuricemia
- Principal Investigator
  
  Yasujima Tomoya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
Elucidation of the Function and Physiological Role of a Novel Polyamine Transporter
- Principal Investigator
  
  Hiroaki Yuasa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University
Elucidation of the molecular mechanism of intestinal absorption of pyridoxine and its application to therapeutic strategy for cancerPrincipal Investigator
- Principal Investigator
  
  Yamashiro Takahiro
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya City University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Involvement of Proton-Coupled SLC49A4-Mediated Transport in the Export of Lysosomally Trapped Pyrilamine2024
- Author(s)
  Akino Shogo, Yasujima Tomoya, Shibutani Rei,Yamashiro Takahiro, Yuasa Hiroaki
- Journal Title
  
  Drug Metabolism and Disposition
  
  Volume: 52 Issue: 1 Pages: 19-25
- DOI
  10.1124/dmd.123.001354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21KK0280, KAKENHI-PROJECT-23K06283
[Journal Article] Animal species differences in the pyridoxine transport function of SLC19A3: absence of Slc19a3-mediated pyridoxine uptake in the rat small intestine2022
- Author(s)
  Yamashiro Takahiro, Yasujima Tomoya, Yuasa Hiroaki
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 44 Pages: 100456-100456
- DOI
  10.1016/j.dmpk.2022.100456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15318
[Journal Article] Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H<sup>+</sup>-driven lysosomal pyridoxine exporter2022
- Author(s)
  Akino Shogo, Yasujima Tomoya, Yamashiro Takahiro, Yuasa Hiroaki
- Journal Title
  
  Life Science Alliance
  
  Volume: 6 Issue: 2 Pages: e202201629-e202201629
- DOI
  10.26508/lsa.202201629
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21KK0280, KAKENHI-PROJECT-20K07135, KAKENHI-PROJECT-21K15318
[Journal Article] Identification of the amino acid residues involved in the species-dependent differences in the pyridoxine transport function of SLC19A32022
- Author(s)
  Miyake Kohei, Yasujima Tomoya, Takahashi Syunsuke, Yamashiro Takahiro, Yuasa Hiroaki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 8 Pages: 102161-102161
- DOI
  10.1016/j.jbc.2022.102161
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21KK0280, KAKENHI-PROJECT-21K15318
[Journal Article] Functional characterization of human organic anion transporter 10 (OAT10/SLC22A13) as an orotate transporter2022
- Author(s)
  Shinoda Yutaro、Yamashiro Takahiro、Hosooka Akira、Yasujima Tomoya、Yuasa Hiroaki
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 43 Pages: 100443-100443
- DOI
  10.1016/j.dmpk.2021.100443
- NAID
  210000188785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07159
[Journal Article] Functional Analysis of the Role of Equilibrative Nucleobase Transporter 1 (ENBT1/SLC43A3) in Adenine Transport in HepG2?Cells2020
- Author(s)
  Takenaka Risa、Yasujima Tomoya、Furukawa Junji、Hishikawa Yosuke、Yamashiro Takahiro、Ohta Kinya、Inoue Katsuhisa、Yuasa Hiroaki
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 109 Issue: 8 Pages: 2622-2628
- DOI
  10.1016/j.xphs.2020.04.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07135
[Journal Article] pH-dependent pyridoxine transport by SLC19A2 and SLC19A3: Implications for absorption in acidic microclimates2020
- Author(s)
  Yamashiro Takahiro、Yasujima Tomoya、Said Hamid M.、Yuasa Hiroaki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 50 Pages: 16998-17008
- DOI
  10.1074/jbc.ra120.013610
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07135, KAKENHI-PROJECT-19K16416, KAKENHI-PROJECT-18KK0453
[Presentation] FLVCR1/2のコリン輸送機能解析：CHT1との比較2024
- Author(s)
  山﨑美音, 廣瀬　舞, 保嶋智也, 山城貴弘, 湯浅博昭
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06258
[Presentation] 各種細胞株でのコリン取込におけるFLVCR1/2の寄与の評価2024
- Author(s)
  保嶋智也, 川本彩果, 山城貴弘, 湯浅博昭
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06258
[Presentation] SUBSTRATE-DEPENDENT CHARACTERISTICS IN THE TRANSPORT FUNCTION OF SLC19A3: EXAMINATION OF THE ASPECT OF ITS SENSITIVITY TO FLAVONOIDS2023
- Author(s)
  Hiroaki Yuasa, Saena Yamashita, Takahiro Yamashiro, Tomoya Yasujima
- Organizer
  25th North American ISSX Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0280
[Presentation] SLC19A2/3の蛍光性試験基質としてのamilorideの輸送特性の評価と利用2023
- Author(s)
  松井快人、山本道弘、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬剤学会第38年会
- Data Source
  KAKENHI-PROJECT-23K06283
[Presentation] SLC19A2/3の蛍光性試験基質としてのamilorideの輸送特性の評価と利用2023
- Author(s)
  松井快人、山本道弘、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬剤学会第38年会
- Data Source
  KAKENHI-PROJECT-21KK0280
[Presentation] OAT2/SLC22A7の尿酸輸送機能の動物種差に関わる分子機構2023
- Author(s)
  澁谷玲衣、谷内夏月、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] Analysis of the transport function of SLC19A2/3 for amiloride: utilization as a fluorescent probe substrate2023
- Author(s)
  Kaito Matsui, Michihiro Yamamoto, Takahiro Yamashiro, Tomoya Yasujima, Hiroaki Yuasa
- Organizer
  2023 International Joint Meeting of 23rd ICCP450/38th JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0280
[Presentation] Analysis of the transport function of SLC19A2/3 for amiloride: utilization as a fluorescent probe substrate2023
- Author(s)
  Kaito Matsui, Michihiro Yamamoto, Takahiro Yamashiro, Tomoya Yasujima, Hiroaki Yuasa
- Organizer
  2023 International Joint Meeting of 23rd ICCP450/38th JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06283
[Presentation] ENBT1/SLC43A3によるオロト酸輸送：HEK293細胞一過性発現系及びHepG2細胞での解析2023
- Author(s)
  森本遥香, 髙見華奈, 保嶋智也, 山城貴弘, 湯浅博昭
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K07159
[Presentation] 新規蛍光性SLC19A2/3プローブ基質としてのamilorideの輸送特性2023
- Author(s)
  松井快人、山本道弘、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21KK0280
[Presentation] 新規蛍光性SLC19A2/3プローブ基質としてのamilorideの輸送特性2023
- Author(s)
  松井快人、山本道弘、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会　第143年会
- Data Source
  KAKENHI-PROJECT-21K15318
[Presentation] Comparative evaluation of the choline transport functions of novel choline transporters and choline transporter 12023
- Author(s)
  Mai Hirose, Chitaka Namba, Yosuke Azuma, Tomoya Yasujima, Takahiro Yamashiro, Hiroaki Yuasa
- Organizer
  2023 International Joint Meeting of 23rd ICCP450/38th JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06258
[Presentation] SUBSTRATE-DEPENDENT CHARACTERISTICS IN THE TRANSPORT FUNCTION OF SLC19A3: EXAMINATION OF THE ASPECT OF ITS SENSITIVITY TO FLAVONOIDS2023
- Author(s)
  Hiroaki Yuasa, Saena Yamashita, Takahiro Yamashiro, Tomoya Yasujima
- Organizer
  25th North American ISSX Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06283
[Presentation] Functional characteristics and role of DIRC2/SLC49A4 as a novel lysosomal pyridoxine exporter2022
- Author(s)
  秋野翔伍、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬物動態学会第37回年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] OAT2の尿酸輸送機能の動物種差2022
- Author(s)
  谷内夏月、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] SLC19A2/3のamiloride輸送機能2022
- Author(s)
  山本道弘、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21KK0280
[Presentation] OCT2阻害活性評価における基質依存的な差異：atenolol輸送阻害とMPP+輸送阻害との比較2022
- Author(s)
  細岡晶、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] Functional characteristics and role of DIRC2/SLC49A4 as a novel lysosomal pyridoxine exporter2022
- Author(s)
  Shogo Akino, Takahiro Yamashiro, Tomoya Yasujima, Hiroaki Yuasa
- Organizer
  日本薬物動態学会第37回年会
- Data Source
  KAKENHI-PROJECT-21KK0280
[Presentation] Functional characteristics and role of DIRC2/SLC49A4 as a novel lysosomal pyridoxine exporter2022
- Author(s)
  Shogo Akino, Takahiro Yamashiro, Tomoya Yasujima, Hiroaki Yuasa
- Organizer
  日本薬物動態学会　第37回年会
- Data Source
  KAKENHI-PROJECT-21K15318
[Presentation] SLC19A3のpyridoxine輸送機能の動物種差：ラット小腸におけるSlc19a3のpyridoxine輸送機能欠損の検証2022
- Author(s)
  山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬剤学会　第37年会
- Data Source
  KAKENHI-PROJECT-21K15318
[Presentation] SLC19A2/3のamiloride輸送機能2022
- Author(s)
  山本道弘、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21K15318
[Presentation] ENT類による核酸塩基取込における核酸塩基代謝酵素類の基質特異的協働効果2022
- Author(s)
  小西拓実、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] ENBT1のオロト酸輸送機能2022
- Author(s)
  高見華奈, 保嶋智也, 山城貴弘, 湯浅博昭
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07159
[Presentation] fisetinに対するCNT2の感受性の動物種差に関わるアミノ酸残基2022
- Author(s)
  田中雄大、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] DIRC2のpyrilamine輸送機能及び薬物動態的役割2022
- Author(s)
  秋野翔伍、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] 小腸に発現する新規コリントランスポーターの機能解析2022
- Author(s)
  東洋輔、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] SLC19A3のpyridoxine輸送機能の動物種差に関わるヒト特異的アミノ酸残基2022
- Author(s)
  三宅浩平、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会　第142年会
- Data Source
  KAKENHI-PROJECT-21K15318
[Presentation] オロト酸トランスポーターとしてのSMCT2の機能的同定2022
- Author(s)
  篠田裕太郎、細岡晶、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] SLC19A3のpyridoxine輸送機能の動物種差に関わるヒト特異的アミノ酸残基2022
- Author(s)
  三宅浩平、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] SLC19A3のpyridoxine輸送機能の動物種差：ラット小腸におけるSlc19a3のpyridoxine輸送機能欠損の検証2022
- Author(s)
  山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-21KK0280
[Presentation] SLC19A3のpyridoxine輸送機能の動物種差に関わるアミノ酸残基2021
- Author(s)
  三宅浩平、高橋駿介、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] オロト酸トランスポーターとしてのヒトOAT10の機能的同定2021
- Author(s)
  篠田裕太郎, 細岡晶, 保嶋智也, 山城貴弘, 湯浅博昭
- Organizer
  第36回日本薬物動態学会年会
- Data Source
  KAKENHI-PROJECT-20K07159
[Presentation] Comparative assessment of the uptakes of pyridoxine and thiamine in the rat small intestine: absence of Slc19a3-dependent function of carrier-mediated pyridoxine uptake2021
- Author(s)
  Takahiro Yamashiro, Tomoya Yasujima, Hiroaki Yuasa
- Organizer
  日本薬物動態学会　第37回年会
- Data Source
  KAKENHI-PROJECT-21K15318
[Presentation] OCT2における基質依存的な阻害活性差：atenolol輸送阻害試験とMPP+輸送阻害試験との比較2021
- Author(s)
  細岡晶、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] SLC19A2/3のpyridoxine/thiamine輸送機構：輸送特性の基質間比較解析2021
- Author(s)
  山城貴弘, 保嶋智也, Hamid M. Said, 湯浅博昭
- Organizer
  日本薬剤学会　第36年会
- Data Source
  KAKENHI-PROJECT-21K15318
[Presentation] リソソーム膜局在型の新規pyridoxineトランスポーターの機能解析2021
- Author(s)
  秋野翔伍、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] Functional identification of human OAT10 as an orotate transporter2021
- Author(s)
  篠田裕太郎、細岡晶、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] ENT2の尿酸輸送機能の解析2021
- Author(s)
  間竹勇、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] ENT2の尿酸輸送機能の解析：Caco-2細胞での検証2021
- Author(s)
  間竹勇、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] SLC19A3のpyridoxine輸送機能の動物種差に関わるアミノ酸残基2021
- Author(s)
  三宅浩平、高橋駿介、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21K15318
[Presentation] SLC19A2/3のpyridoxine/thiamine輸送機構：輸送特性の基質間比較解析2021
- Author(s)
  山城貴弘、保嶋智也、Hamid M. Said、湯浅博昭
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] Functional characterization of the carrier-mediated choline transport system in Caco-2 cells2021
- Author(s)
  難波知尭、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] Comparative assessment of the uptakes of pyridoxine and thiamine in the rat small intestine: absence of Slc19a3-dependent function of carrier-mediated pyridoxine uptake2021
- Author(s)
  山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] BCRPの尿酸排出輸送活性の評価系としてのSNBT1/BCRP共発現細胞の利用：フラボノイド類の阻害効果2021
- Author(s)
  石牧礼子、奈良佳幸、保嶋智也、山城貴弘、太田欣哉、井上勝央、湯浅博昭
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] ヒトCNT2及びCNT3に対するフラボノイド類の阻害作用の速度論的解析2021
- Author(s)
  難波知尭、矢嶋陽菜、黒田大祐、保嶋智也、山城貴弘、湯浅博昭
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] fisetin及び類縁フラボノイドに対するCNT2の感受性の動物種差2021
- Author(s)
  田中雄大、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K07135
[Presentation] SLC19A3の脳神経変性疾患関連遺伝子変異と輸送機能との関係2020
- Author(s)
  三宅浩平、小川有沙、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会　第140年会
- Data Source
  KAKENHI-PROJECT-19K16416
[Presentation] SLC19A3によるpyridoxine及びthiamineの輸送に対するフラボノイド類の阻害作用の解析2020
- Author(s)
  山下紗瑛奈、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本薬学会　第140年会
- Data Source
  KAKENHI-PROJECT-19K16416
[Presentation] SLC19A3に対するフラボノイド類の阻害作用2019
- Author(s)
  山下紗瑛奈、山城貴弘、保嶋智也、湯浅博昭
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2019
- Data Source
  KAKENHI-PROJECT-19K16416
[Presentation] Species differences in SLC19A3 for pyridoxine transport function2019
- Author(s)
  Kohei Miyake, Shunsuke Takahashi, Takahiro Yamashiro, Tomoya Yasujima, Hiroaki Yuasa
- Organizer
  日本薬物動態学会　第34回年会
- Data Source
  KAKENHI-PROJECT-19K16416
[Presentation] Functional identification of SLC19A2/3 as pyridoxine transporters2019
- Author(s)
  Takahiro Yamashiro, Tomoya Yasujima, Hiroaki Yuasa
- Organizer
  日本薬物動態学会　第34回年会
- Data Source
  KAKENHI-PROJECT-19K16416

1. Yasujima Tomoya (50753555)

# of Collaborated Projects: 5 results

# of Collaborated Products: 34 results
2. Hiroaki Yuasa (20191471)

# of Collaborated Projects: 5 results

# of Collaborated Products: 34 results
3. 大澤匡弘 (80369173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yamashiro Takahiro 山城 貴弘

Research Projects

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Co-Researchers

新規小胞膜局在型モノアミントランスポーターの機能解析と創薬標的としての有望性評価

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新規コリントランスポーター類の分子機能と生理的及び薬物動態的役割

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Elucidation of substrate recognition mechanism of SLC19A3 to establish the molecular basis for medical applicationsPrincipal Investigator

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新規ピリドキシントランスポーターとイオン輸送体の応答によるピリドキシン動態の解明Principal Investigator

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Elucidation of molecular mechanism of substrate-dependent transport function of SLC19A3 and its relevance to pathologyPrincipal Investigator

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Elucidation of molecular mechanism that triggers onset of gout from hyperuricemia

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Elucidation of the Function and Physiological Role of a Novel Polyamine Transporter

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Elucidation of the molecular mechanism of intestinal absorption of pyridoxine and its application to therapeutic strategy for cancerPrincipal Investigator

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[Journal Article] Involvement of Proton-Coupled SLC49A4-Mediated Transport in the Export of Lysosomally Trapped Pyrilamine2024

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[Journal Article] Animal species differences in the pyridoxine transport function of SLC19A3: absence of Slc19a3-mediated pyridoxine uptake in the rat small intestine2022

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[Journal Article] Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H<sup>+</sup>-driven lysosomal pyridoxine exporter2022

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[Journal Article] Identification of the amino acid residues involved in the species-dependent differences in the pyridoxine transport function of SLC19A32022

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[Journal Article] Functional characterization of human organic anion transporter 10 (OAT10/SLC22A13) as an orotate transporter2022

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NAID

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[Journal Article] Functional Analysis of the Role of Equilibrative Nucleobase Transporter 1 (ENBT1/SLC43A3) in Adenine Transport in HepG2?Cells2020

Author(s)

Yamashiro Takahiro 山城貴弘