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HOSAKA Masahiko  穂坂 正彦

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… Alternative Names

穗坂 正彦  ホサカ マサヒコ

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Researcher Number 30106330
External Links
Affiliation (based on the past Project Information) *help 2001: Yokohama City University School of Medicine, Department of Urology, Professor
1986 – 2001: 横浜市立大学, 医学部, 教授
1992: 横浜市立大学, 医学部泌尿器科, 教授
1991: 横浜市立大学, 医学部・泌尿器科学, 教授
1990: 横浜市立大学, 医学部(泌尿器科学), 教授
1989: 横浜市立大学, 医学部泌尿器科, 教授
Review Section/Research Field
Principal Investigator
Urology
Except Principal Investigator
Urology
Keywords
Principal Investigator
前立腺癌 / PS3遺伝子 / P53遺伝子 / 電気穿孔法 / 遺伝子治療 / 5α-reductase / LNCaP細胞 / 5alpha-reductase
Except Principal Investigator
前立腺癌 / 腎癌 … More / 癌抑制遺伝子 / 腎細胞癌 / ヒト腎癌 / アンドロゲン / VHL遺伝子 / 再燃 / renal cell carcinoma / TiO_2 / 癌治療 / epididymis / 遺伝子発現 / common disease / 精子形成 / 尿路性器癌 / VHL gene / prostate cancer / Differential Display / Differential Display法 / tumor suppressor gene / carcinoma / Prostate cancer / アンドロゲンレセプター / Testosterone / 酸化チタン / 再燃現象 / アンドロゲンレセプター遺伝子 / ヒト前立腺癌 / Cancer treatment / 細胞膜 / 膀胱癌 / 光励起半導体 / down-regulation / 精巣上体 / Retinoblastoma遺伝子 / c-myc / cーmyc遺伝子 / liposome / Signal transduction / Phosphatidylinositol metabolism / Cell menbrane / c-myc遺伝子 / ミトコンドリア膜 / イノシトールリン脂質 / リポゾーム / 癌遺伝子 / 細胞の情報伝達 / イノシトールリン脂質代謝 / 癌細胞膜 / DNA microarray analyses / genitourinary cancer / Infantile anomaly in male sex organ / BPH / urinary tract caluculi / マイクロアレイ / 腎尿路癌 / 遺伝子型 / 多因子疾患 / 精巣腫瘍 / 尿路上皮癌 / 尿路結石 / microarray / DNA microaray / 小児尿路性器奇形 / 前立腺肥大症 / 尿路結石症 / Stem cell / Transplantation / Spermatogonia / Spermatogeneiss / GnRH / 男性不妊 / GFP / 幹細胞 / 移植 / 精原細胞 / transcription factor / Steroid hormone orphan receptor / ステロイドホルモン・オーファンレセプター / スチロイドホルモン・オーファンレセプター / ルシフェラーゼ / 転写因子 / ステロイドホルモンオーファンレセプター / Liprin? gene / nmt55 gene / OSM-? gene / Hormone Refractory / 再熱 / Liprinα-2遺伝子 / nmt55遺伝子 / OSM-β遺伝子 / DHL遺伝子 / testicular tumour / male infertility / spermatogenesis / germ cell / zinc finger gene / 特発性不妊症 / Zincフィレガー遺伝子 / 特発性男子不妊症 / 生殖細胞 / Zincフィンガー遺伝子 / Urogenital Cancer / Photocatalysis / Fine metal particles / 遺伝子治療 / 光触媒 / 微粒子打ち込み法 / APOPTOSIS / STEROID RECEPTOR / PROSTATE CANCER / アポトーシス / ステロイドレセプター / mutation / tumor suppressor / renal cell / 遺伝子変異 / liprin-α2 / defferential display / Telomerase / 遺伝子 / 男性ホルモン依存性 / リプリンα-2遺伝子 / テロメレース / rat / androgen responsive gene / androgen receptor / androgen / アンドロゲン応当遺伝子 / 男子不妊症 / 男子生殖器 / ラット / 副精巣 / アンドロゲン応答遺伝子 / Positive Control / Gonadotropin / Pituitary gland / フィードバック調節 / ゴナドトロピン / VHL / rsnal cell / VHL病 / gene alterations / Reactivation / 再燃前立腺癌 / RB遺伝子 / P53遺伝子 / 遺伝子変化 / retinoblastoma gene / p53gene / von Hippel-Lindau gene / von Hippel-Lindau病遺伝子 / retinoblastoma遺伝子 / p53遺伝子 / von Hi ppel-Llndau病癌抑制遺伝子 / Paracrine Control / Leydig Cell / Sertoli Cell / テストマテロン / パラクリンコントロール / テストステロン / ライディッヒ細胞 / セルトリ細胞 / Bladder cancer / TiO2 / photoexcited semiconductor / 光半導体癌法 / Spermatozoa / Electric stimulation / Epididymis / 副睾丸 / 電位負荷 / 精子運動 / 精子 / 電気刺激 / Androgen Receptor / Growth facor / Tumor suppressor gene / Oncogene / Prostate Cancer / SSCP法 / 増殖因子遺伝子 / 増殖特性 / 増殖因子 / がん抑制遺伝子 / がん遺伝子 / Human Bladder cancer / Semi-conductor Particles / Human cancer cells / Photoexcited Ti02 / Photo-chemical reaction / ヒト膀胱癌 / 光化学療法 / TiO_2微粒子 / antiandrogens / estrogens / testosterone 5 alpha -reductase / 阻害剤 / LH-RHアナログ / 5α-還元酵素 / ONOー3805 / flutamide / LHーRHanalogue / finasteride / inhibitor / 5αーreductase / アンチアンドロゲン / エストロゲン / 5α-reductase / 免疫化学療法 / 細胞膜情報伝達機構 / 遺伝子発現調節 / サイトカイン / インタ-フェロン / TNF / ガン遺伝子 / myb / スラミン / EGF受容体 / cーmyc / 転移 / 進展 / 悪性度 / B-myb / A-myb / EGF Receotor / Notrhern blot法 / 癌遺伝子発現 / Pー53遺伝子 / Retimoblastoma遺伝子 / cーerbBー1遺伝子 / Bーmyb遺伝子 Less
  • Research Projects

    (27 results)
  • Co-Researchers

    (20 People)
  •  A sutdy for analyzing causative genes for common diseases in urinary tract and male sex organs

    • Principal Investigator
      SHUIN Taro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Urology
    • Research Institution
      Kochi Medical School
  •  電気穿孔法を用いる尿路性器癌の遺伝子治療の開発研究Principal Investigator

    • Principal Investigator
      穂坂 正彦
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Study of the identification of new genes inducing hormone refractory prostate cancer

    • Principal Investigator
      KUBOTA Yoshinobu
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University Grant-in Aid for Scientific Research (B)(2)
  •  Functional Analysis of Steroid hormone orphan receptor in hormone refractory prostate cancer

    • Principal Investigator
      UEMURA Hiroji
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Analysis of spermatogonial proliferation with technique of spermatogonial transplantation-A trial for improving spermatogenic activity

    • Principal Investigator
      OGAWA Takehiko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Study of the development a new type of treatment of urogenital cancer by using surface modified fine metal particles.

    • Principal Investigator
      KUBOTA Yoshinobu
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Studies on a KRAB zinc finger gene, highly expressed in the human testis

    • Principal Investigator
      TAKEDA Mitsumasa
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Functional Analysis of the von Hippel-Lindau Disease Tumor Suppressor Gene

    • Principal Investigator
      YAO Masahiro
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Study of the Identification of new genes associated with development and recurrence of prostate cancer

    • Principal Investigator
      KUBOTA Yoshinobu
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Molecular Genetic Study of the VHL Tumor Suppressor Gene in Human Renal Cell Carcinoma

    • Principal Investigator
      YAO Masahiro
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  ANALYSIS OF TR3 RECEPTOR IN APOPTOSIS OF PROSTATE CANCER AND APPLICATION FOR DIAGNOSIS OF PROSTATE CANCER RECCURENCE

    • Principal Investigator
      UEMURA Hiroji
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      YOKOHAMA CITY UNIVERSITY
  •  Positive Control of Gonadotropin Secretion by Androgen

    • Principal Investigator
      NOGUCHI Kazumi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Studies on molecularbiological approach of male infertility-Isolation of androgen responsive genes by genomic binding-site method.

    • Principal Investigator
      TAKEDA Mitsumasa
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Analysis of genes involving in reactivation of prostate cancer

    • Principal Investigator
      KUBOTA Yoshinobu
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Mutational Analysis of the VHL Tumor Suppressor Gene in Sporadic Renal Cell Carcinoma

    • Principal Investigator
      YAO Masahiro
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Application of photoexcited TiO2 semicondoctor to the treatment of bladder cancer

    • Principal Investigator
      KUBOTA Yoshinobu
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Intercellular Communication Between Sertoli Cell and Leydig Cell

    • Principal Investigator
      NOGUCHI Kazumi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Anew trial of Genetic dlagnosisand treatment of kidney cancer based on the abnormallty in the oncogene and tumor suppressor gene Head invastigator ; Registered invastigators : Resgistered

    • Principal Investigator
      SHUIN Taro
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kochi Medical School
      Yokohama City University
  •  前立腺癌の分化度と男性ホルモン作用機構上の遺伝子発現の差に基づく悪性度診断Principal Investigator

    • Principal Investigator
      穂坂 正彦
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Bulk collection of epididymal tail spermatozoa by means of electric stimulation

    • Principal Investigator
      KINOSHITA Yuzo
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  ヒト腎癌に特異な癌遺伝子群の活性化機構の解明および遺伝子診断法と治療法の開発

    • Principal Investigator
      執印 太郎
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Analysis of the genes involved in the growth of human professor

    • Principal Investigator
      KUBOTA Yoshinobu
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  癌遺伝子の発現によるヒト腎癌の悪性度分類と遺伝子情報に基づく診断法の開発

    • Principal Investigator
      SHUIN Taro
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  A Reserch for Regulation of the Human Epididymal 5 alpha-Reductase Intended in Development of Male Cotraceptives.

    • Principal Investigator
      KINOSHITA Yuzo
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Development of a new cancer therapy using photoexcited semiconductor particles

    • Principal Investigator
      KUBOTA Yoshinobu
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B).
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  ガン遺伝子の発現機構にもどづく腎癌の免疫・化学療法の開発

    • Principal Investigator
      窪田 吉信
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Phosphatidylinositol turnover of cancer cell menbrane and development of new treatment of renal cell carcinoma

    • Principal Investigator
      KUBOTA Yoshinobu
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  • 1.  KUBOTA Yoshinobu (10106312)
    # of Collaborated Projects: 17 results
    # of Collaborated Products: 0 results
  • 2.  SHUIN Taro (80179019)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  KINOSHITA Yuzo (00186298)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  UEMURA Hiroji (50244439)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  YAO Masahiro (00260787)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  NOGUCHI Kazumi (10164675)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  TAKEDA Mitsumasa (70244499)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  FUJISHIMA Akira (30078307)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  加藤 隆史 (70214377)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  HASHIMOTO Kazuhito (00172859)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  川崎 千尋 (20234057)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SAITO Kazuo (90264647)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KISHIDA Takeshi (60254166)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  OGAWA Takehiko (50254222)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  FUJIOKA Tomoaki (80173409)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  TSUKAMOTO Taiji (50112454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MIKI Tuneharu (10243239)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  AKAZA Hideyuki (70010486)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  公文 裕己 (30144760)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  郡 健二郎 (30122047)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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