TAKAGI Akira 高木明

Researcher Number	30135371
Other IDs
Affiliation (based on the past Project Information) *help	2018: 名古屋大学, 医学系研究科(保健), 客員研究者 2016 – 2018: 名古屋大学, 医学系研究科(保健), 准教授 2015: 名古屋大学, 医学(系)研究科(研究院), 准教授 2015: 名古屋大学, 大学院医学系研究科, 准教授 2012 – 2014: 名古屋大学, 医学(系)研究科(研究院), 助教 … More 2013: 名古屋大学, 大学院医学系研究科, 助教 2012: 名古屋大学, 医学系研究科(保健), 助教 2012: 名古屋大学, 大学院・医学系研究科(保健), 助教 2007 – 2011: Nagoya University, School of Health Sciences, Professor 2008: 名古屋大学, 医学部(保健学科), 助教 2002 – 2006: 名古屋大学, 医学部, 助手 1999 – 2000: 名古屋大学, 医学部, 助手 1986 – 1987: 名古屋大学, 医療技術短期大学部, 助手 Less
Review Section/Research Field	Principal Investigator Laboratory medicine Except Principal Investigator Laboratory medicine / Hematology / Psychiatric science / Laboratory medicine / Hematology
Keywords	Principal Investigator 病態解析 / アンチトロンビン抵抗性 / プロトロンビンアクチベータ / 変異型プロトロンビン / アンチトロンビン抵抗性検出法 / アンチトロンビン / 凝固第X因子 / 抗血栓薬 / 血栓傾向 / トロンボモジュリン抵抗性 … More / プロトロンビン分子異常 / 危険因子 / 静脈血栓塞栓症 / 病態検査学 / 遺伝子変異 / プロトロンビン / 検査法開発 / 血栓症リスク / 制御因子抵抗性 / 変異プロトロンビン / プロトロンビン変異 / 臨床血液学 … More Except Principal Investigator sphingosine kinase 1 / promoter analysis / gene expression / Sp1 protein / 転写調節 / MEN2 type tumor / GDNF / sphingolipid metabolites / acute leukemia / quantitative RT-PCR / May-Hegglin anomaly / MYH9 / NMMHCA / Trk A receptor / nerve growth factor / PAI-1 / methylation specific PCR / PCR based HUMARA / アンチトロンビン・レジスタンス（ATR） / トロンビン / プロモーター解析 / ATRA / スフィンゴシンキナーゼ1 / 内科 / 人工授精 / アンチトロンビン・レシスタンス（ATR） / R593Lノックインマウス / ジーンタ一ゲティング / アンチトロンビン / Arg593Leuノックインマウス / Na+結合領域 / ATR残存凝固活性 / 自動化機器 / ATR検出・臨床検査法 / 遺伝子異常 / プロトロンビン / Apnea / Acetazolamide / Plasma norepinephrine / Sleep architecture / Arterial oxygen desaturation / Polysomnography / Sleep apnea syndrome / 血奬ノルアドレナリン / SOD Index / 無呼吸 / アセタゾラミッド / 血漿ノルアドレナリン / 睡眠構築 / 動脈血酸素飽和度 / ポリソムノグラフィ / 睡眠時無呼吸症候群 / Elecrophysiology / myelodysplastic syndrome / RET signal / myelodysplastic syndromes / MEN2 type promoter / anti-cancer drug sensitivity / myelodysplastic sundrome / sphinosine kinase1 / Knock in mouse / Alport symptom / Knock out mouse / immunostaining / macrothrombocytopenia / 巨大血小板 / Cre-recombinase / ノックイン / ノックインマウス / Alport徴候 / 欠失マウス / 免疫染色解析 / May-Hegglin異常症 / 巨大血小板性血小板減少症 / all trans retinoic acid / neuronal apoptosis / SPHK1 gene expression / anti human SPHK1 antibody / Spl protein / obese / aged, older / TF / restraint stress / thrombotic diseases / stress / competitive RT-PCR法 / マウス / 血栓傾向 / in situ hybridization法 / 加齢 / 抗TNF-α抗体 / 老齢 / TF(組織因子)発現 / 肥満 / 加齢(老齢) / TF(組織因子) / 拘束ストレス負荷 / 血栓性疾患 / ストレス / polyclonal antibody / スフィンゴシンキナーゼ / プロモータ解析 / MEG-O1 / ポリクローナル抗体 / hematopoietic colonies / X chromosome inactivation / HUMARA-MSP / clonality / hematopoiesis / HUMARA / 造血幹細胞 / p15メチル化 / 鉄芽球性貧血 / PCR based HUMARA法 / 造血クローン性 / 造血コロニー / X染色体の不活化 / HUMARA-MSP法 / クローン性 / 造血 / MDS / transcription / CREB / serum-depleted condition / hypoxia / USP2 / アンドロジェン / 前立腺癌細胞株 / ACDase / 血清除去 / SPHK2 / 代謝酵素遺伝子発現調節 / スフィンゴ脂質代謝 / 悪性腫瘍細胞株 / 白血病細胞株 / 酸性スフィンゴミエリナーゼ / レスベラトロール / Anti-cancer action / Phytochemical / Food ingredient / Stress response / Cancer cell / Sphingolipid metabolism / トロンボモジュリン／プロテインC経路 / R593Lプロトロンビン-マウス / ﾄﾛﾝﾎﾞﾓｼﾞｭﾘﾝ/ﾌﾟﾛﾃｲﾝC経路 / R593Lﾌﾟﾛﾄﾛﾝﾋﾞﾝ-ﾏｳｽ / ｱﾝﾁﾄﾛﾝﾋﾞﾝ・ﾚｼﾞｽﾀﾝｽ(ATR) / 相同組換え / R593Lプロトロンビン-ノックインマウス / トロンボモジュリン / 一塩基置換 / 遺伝性血栓症 / プロトロンビン異常症 / アンチトロンビン-レジスタンス（ATR） / PKC delta / Sp1転写因子 / MCF-7細胞株 / NSmase2 / 国際情報交換 / ERK pathway / S1P receptor 2 / CD44 / human colon cancer cell / chemical differentiation / c-Myb / Friend cell / SPHK1 / human cancer cell lines / anti-cancer drug / metabolic enzyme / sphingolipid / スクリーニング検査法 / プロテインS欠損症 / プロテインC欠損症 / アンチトロンビン欠損症 / ｽｸﾘ―ﾆﾝｸﾞ検査法 / ｱﾝﾁﾄﾛﾝﾋﾞﾝ抵抗性 / ﾌﾟﾛﾃｲﾝS欠損症 / ﾌﾟﾛﾃｲﾝC欠損症 / ｱﾝﾁﾄﾛﾝﾋﾞﾝ欠損症 / 原因遺伝子変異 / アンチトロンビン抵抗性 / 遺伝子変異 / 先天性血栓性素因 / 静脈血栓塞栓症 / 臨床血液学 / PKC alpha / タンパク質リン酸化 / HuR / AUF1 / 3'-UTR / v-SRCガン遺伝子 / mRNA寿命の延長 / ダウノルビシン / 転写抑制機序 / 転写因子およびプロモーター領域結合部位 / 脂肪分化ならびに癌化 / PLD1 transcription / GATA-4 protein / DNA pulldown assay and chromatin immunoprecipitation assay / cellular S1P level / real time RT-PCT / human lung cancer cell lines / sphingosine 1-phosphate lyase / ホスホリパーゼD1,ホスホリパーゼD2 / スフィンゴシン1リン酸リアーゼ / 中性スフィンゴミエリナーゼ2 / セラミドキナーゼ / スフィンゴシンキナーゼ2 / スフィンゴシン1リン酸 / セラミド / PS mRNA / エストラディオール(E2) / HepG2細胞 / ルシフェラーゼ・レポーター解析 / プロモーター / 遺伝子欠失 / PROS1遺伝子 / プロテインS(PS)欠損症 Less

Development of a new detection method in antithrombin resistance to avoid the effect of antithrombotic drug treatmentPrincipal Investigator
- Principal Investigator
  
  TAKAGI AKIRA
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Novel mutation search of antithrombin resistance and its pathological analysis research by mouse model
- Principal Investigator
  
  Kojima Tetsuhito
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Stress response of cancer cells focusing the sphingolipid metabolism and its modulation by food ingredients
- Principal Investigator
  
  MURATE Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Chubu University
  Nagoya University
Molecular elucidation of antithrombin resistance mechanism and development of thrombophilia model mouse.
- Principal Investigator
  
  Kojima Tetsuhito
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Development of new examination methods for thrombotic tendency with TM resistance and FXa AT resistancePrincipal Investigator
- Principal Investigator
  
  TAKAGI AKIRA
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
The involvement of sphingolipid metabolism in anti cancer drug sensitivity of malignant cells
- Principal Investigator
  
  MURATE Takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Gene analysis of a novel thrombotic risk factor; antithrombin-resistance.
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Development of new analytical method for antithrombin resistancePrincipal Investigator
- Principal Investigator
  
  TAKAGI Akira
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Involvement and abnormality of lysosphingolipid metabolic enzymes in malignant diseases
- Principal Investigator
  
  MURATE Takashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Elucidation of Molecular basis of inherited and acquired protein S deficiency as a thrombosis risk factor
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Aberrant expression of sphingosine kinase and its pathological significance of malignant tumors and neuronal degenerative diseases
- Principal Investigator
  
  MURATE Takashi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Molecular mechanisms of thrombosis in mouse model induced by age and stress
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Basic analysis of sphingolipid metabolising enzyme and its application to the diagnosis of hematological and neuronal diseases
- Principal Investigator
  
  TAKASHI Murate
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Molecular mechanisms of thrombosis in mouse model induced by age and stress
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
The significance of serum sphingosine 1-phospahte in hematological diseases and the regulatory mechanism of sphingosine kinase
- Principal Investigator
  
  MURATE Takeshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Analysis of the efficiency of the separation of normal hematopoietic stem cells of myelodysplastic syndrome for auto stem cell transplantation
- Principal Investigator
  
  MURATE Takashi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Pathophysiology and therapy in patients with sleep apnea syndromes
- Principal Investigator
  
  OKADA Tamotsu
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  College of Medical Technology, Nagoya University

[Book] ファーマナビゲーター抗凝固療法編2015
- Author(s)
  高木夕希、小嶋哲人
- Total Pages
  415
- Publisher
  株式会社メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-25293129
[Book] Annual Review 2016血液2015
- Author(s)
  高木夕希、小嶋哲人
- Total Pages
  234
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25293129
[Book] 臨床検査法提要（改訂第34版）2015
- Author(s)
  小嶋哲人、高木明
- Total Pages
  1970
- Publisher
  金原出版株式会社
- Data Source
  KAKENHI-PROJECT-25293129
[Book] 臨床検査法提要（改訂第34版）2015
- Author(s)
  小嶋哲人、高木明
- Total Pages
  21
- Publisher
  金原出版株式会社
- Data Source
  KAKENHI-PROJECT-25460683
[Journal Article] Apparent synonymous mutation F9 c.87A>G causes secretion failure by in-frame mutation with aberrant splicing.2019
- Author(s)
  Odaira K, Tamura S, Suzuki N, Kakihara M, Hattori Y, Tokoro M, Suzuki S, Takagi A, Katsumi A, Hayakawa F, Okamoto S, Suzuki A, Kanematsu T, Matsushita T, Kojima T
- Journal Title
  
  Thrombosis Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09825
[Journal Article] Molecular basis of SERPINC1 mutations in Japanese patients with antithrombin deficiency.2019
- Author(s)
  Tamura S, Hashimoto E, Suzuki N, Kakihara M, Odaira K, Hattori Y, Tokoro M, Suzuki S, Takagi A, Katsumi A, Hayakawa F, Suzuki A, Okamoto S, Kanematsu T, Matsushita T, Kojima T
- Journal Title
  
  Thrombosis Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09825
[Journal Article] Combined deficiency of factors V and VIII by chance coinheritance of parahaemophilia and haemophilia A, but not by mutations of either LMAN1 or MCFD2, in a Japanese family.2018
- Author(s)
  Suzuki S, Nakamura Y, Suzuki N, Yamazaki T, Takagi Y, Tamura S, Takagi A, Kanematsu T, Matsushita T, Kojima T
- Journal Title
  
  Haemophilia.
  
  Volume: 24 Issue: 1
- DOI
  10.1111/hae.13360
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09825, KAKENHI-PROJECT-17H05073
[Journal Article] アンチトロンビン抵抗性の診断　-検査法を中心に-2018
- Author(s)
  高木明、田村彰吾、小嶋哲人
- Journal Title
  
  日本検査血液学会誌
  
  Volume: 19 Pages: 393-400
- Data Source
  KAKENHI-PROJECT-16K08967
[Journal Article] Familial pulmonary thromboembolism with a prothrombin mutation and antithrombin resistance.2018
- Author(s)
  10)Yoshida R, Seki S, Hasegawa J, Koyama T, Yamazaki K, Takagi A, Kojima T, Yoshimura M
- Journal Title
  
  J Cardiol Cases.
  
  Volume: in press Issue: 6 Pages: 197-199
- DOI
  10.1016/j.jccase.2018.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09825, KAKENHI-PROJECT-16K08967
[Journal Article] Optimisation of antithrombin resistance assay as a practical clinical laboratory test: Development of prothrombin activator using factors Xa/Va and automation of assay2018
- Author(s)
  Tamura S.、Suga Y.、Tanamura M.、Murata-Kawakami M.、Takagi Y.、Hottori Y.、Kakihara M.、Suzuki S.、Takagi A.、Kojima T.
- Journal Title
  
  International Journal of Laboratory Hematology
  
  Volume: 40 Issue: 3 Pages: 312-319
- DOI
  10.1111/ijlh.12786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19910, KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-16K08967, KAKENHI-PROJECT-16K09825
[Journal Article] Vwf K1362A resulted in failure of protein synthesis in mice．2018
- Author(s)
  Sanda N, Suzuki N, Suzuki A, Kanematsu T, Kishimoto M, Hasuwa H, Takagi A, Kojima T, Matsushita T, Nakamura S
- Journal Title
  
  Int J Hematol.
  
  Volume: in press Issue: 4 Pages: 428-435
- DOI
  10.1007/s12185-017-2394-y
- NAID
  120006501193
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09825, KAKENHI-PROJECT-17K09902
[Journal Article] Clinical and biochemical characterization of the prothrombin Belgrade mutation in a large Serbian pedigree: new insights into the antithrombin resistance mechanism.2017
- Author(s)
  Miljic P, Gvozdenov M, Takagi Y, Takagi A, Pruner I, Dragojevic M, Tomic B, Bodrozic J, Kojima T, Radojkovic D, Djordjevic V.
- Journal Title
  
  J Thromb Haemost.
  
  Volume: 15 Issue: 4 Pages: 670-677
- DOI
  10.1111/jth.13618
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08967, KAKENHI-PROJECT-16K09825
[Journal Article] In vitro exploration of latent prothrombin mutants conveying antithrombin resistance.2017
- Author(s)
  Tamura S, Murata-Kawakami M, Takagi Y, Suzuki S, Katsumi A, Takagi A, Kojima T.
- Journal Title
  
  Thromb Res.
  
  Volume: 159 Pages: 33-38
- DOI
  10.1016/j.thromres.2017.09.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09451, KAKENHI-PROJECT-16K08967, KAKENHI-PROJECT-16K09825, KAKENHI-PROJECT-17H05073
[Journal Article] Missense mutations in the gene encoding prothrombin corresponding to Arg596 cause antithrombin resistance and thrombomodulin resistance2016
- Author(s)
  Takagi Y, Murata M, Kozuka T, Nakata Y, Hasebe R, Tamura S, Takagi A, Matsushita T, Saito H, Kojima T.
- Journal Title
  
  THROMBOSIS AND HAEMOSTASIS
  
  Volume: 116 Issue: 12 Pages: 1022-31
- DOI
  10.1160/th16-03-0223
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16J08029, KAKENHI-PROJECT-26860723, KAKENHI-PROJECT-16K08967, KAKENHI-PROJECT-16K09825
[Journal Article] Progestin isoforms provide different levels of protein S expression in HepG2 cells.2016
- Author(s)
  Kozuka, Toshihiro Tamura, Shogo Kawamura, Nami Nakata, Yukiko Hasebe, Ryo Makiyama, Ayumi Takagi, Yuki Murata, Moe Mizutani, Naoki Takagi, Akira Kojima, Tetsuhito
- Journal Title
  
  Thrombosis research
  
  Volume: 145 Pages: 40-5
- DOI
  10.1016/j.thromres.2016.07.007
- NAID
  120005895232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860723, KAKENHI-PROJECT-16K09825
[Journal Article] The first case of antithrombin-resistant prothrombin Belgrade mutation in Japanese2016
- Author(s)
  Kishimoto M, Suzuki N, Murata M, Ogawa M, Kanematsu T, Takagi A, Kiyoi H, Kojima T, Matsushita T
- Journal Title
  
  Ann Hematol.
  
  Volume: 95 Pages: 541-542
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460683
[Journal Article] Distinct X chromosomal rearrangements in four haemophilia B patients with entire F9 deletion.2016
- Author(s)
  Nakamura Y, Ando Y, Takagi Y, Murata M, Kozuka T, Nakata Y, Hasebe R, Takagi A, Matsushita T, Shima M, Kojima T.
- Journal Title
  
  Haemophilia.
  
  Volume: 22 Issue: 3 Pages: 433-439
- DOI
  10.1111/hae.12849
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09825
[Journal Article] 新たな血栓性素因：アンチトロンビンレジスタンス2016
- Author(s)
  小嶋哲人、高木明、村田萌、高木夕希
- Journal Title
  
  日本産婦人科・新生児血液学会誌
  
  Volume: 25 Pages: 66-77
- Data Source
  KAKENHI-PROJECT-16K08967
[Journal Article] The first case of antithrombin-resistant prothrombin Belgrade mutation in Japanese.2016
- Author(s)
  Kishimoto M, Suzuki N, Murata M, Ogawa M, Kanematsu T, Takagi A, Kiyoi H, Kojima T, Matsushita T
- Journal Title
  
  Ann Hematol.
  
  Volume: 95 Issue: 3 Pages: 541-542
- DOI
  10.1007/s00277-015-2533-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293129
[Journal Article] 新たな血栓性素因：アンチトロンビンレジスタンス2016
- Author(s)
  小嶋哲人、高木明、村田萌、高木夕希
- Journal Title
  
  日本産婦人科・新生児血液学会誌
  
  Volume: 25 Pages: 66-72
- Data Source
  KAKENHI-PROJECT-25460683
[Journal Article] Increased Acid Ceramidase Expression depends on Upregulation of Androgen-dependent Deubiquitinases, USP2, in a Human Prostate Cancer Cell Line, LNCaP.2015
- Author(s)
  Naoki Mizutani, Minami Inoue, Yukari Omori, Hiromi Ito, Keiko Tamiya-Koizumi, Akira Takagi, Tetsuhito Kojima, Mitsuhiro Nakamura, Soichiro Iwaki, Masahiro Nakatochi, Motoshi Suzuki, Yoshinori Nozawa, Takashi Murate
- Journal Title
  
  J. Biochem.
  
  Volume: 印刷中 Issue: 4 Pages: 309-319
- DOI
  10.1093/jb/mvv039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460203, KAKENHI-PROJECT-26460674, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-26290051
[Journal Article] アンチトロンビンレジスタンス ―新しい遺伝性血栓性素因―2015
- Author(s)
  小嶋哲人、高木明、村田萌、高木夕希
- Journal Title
  
  臨床血液
  
  Volume: 56 Pages: 632-637
- NAID
  130005093096
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460683
[Journal Article] Antithrombin resistance: a new mechanism of inherited thrombophilia2015
- Author(s)
  小嶋哲人, 高木明, 村田萌, 高木夕希
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 56 Issue: 6 Pages: 632-638
- DOI
  10.11406/rinketsu.56.632
- NAID
  130005093096
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J03741, KAKENHI-PROJECT-25293129
[Journal Article] Increased SPHK2 transcription of human colon cancer cells in serum-depleted culture: the involvement of CREB transcription factor.2015
- Author(s)
  Mizutani N, Omori Y, Tanaka K, Ito H, Takagi A, Kojima T, Nakatochi M, Ogiso H, Kawamoto Y, Nakamura M, Suzuki M, Kyogashima M, Koizumi K, Nozawa Y, Murate T.
- Journal Title
  
  J Cell Biochem
  
  Volume: 116 Issue: 10 Pages: 2227-2238
- DOI
  10.1002/jcb.25173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-26460674, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-26290051
[Journal Article] RhoF Promotes Murine Marginal Zone B Cell Development.2014
- Author(s)
  Kishimoto M, Matsuda T, Yanase S, Katsumi A, Sezuki N, Ikejiri M, Takagi A, Ikawa M, Kojima T, Kunishima S, Kiyoi H, Naoe T, Matsushita T, Maruyama M
- Journal Title
  
  Nagoya J Med Sci.
  
  Volume: 76 Pages: 293-305
- NAID
  120005468127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293129
[Journal Article] High prophylactic LMWH dose successfully suppressed hemostatic activation in pregnant woman with a new prpthrombin c.1787G>A mutation.2014
- Author(s)
  Kovac M, Elezovic I, Mikovic V, Djordjevic V, Radojkovic D, Lalic-Cosic S, Murata M, Takagi A, Kojima T
- Journal Title
  
  Thromb Res.
  
  Volume: 135 Issue: 2 Pages: 420-422
- DOI
  10.1016/j.thromres.2014.12.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J03741, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-25460683
[Journal Article] Antithrombin- resistant prothrombin Yukuhashi mutation also causes thrombomodulin resistance in fibrinogen clotting but not in protein C activation.2014
- Author(s)
  Takagi Y, Kato I, Ando Y, NakamuraY, Murata M, Takagi A, Murate T, Kojima T
- Journal Title
  
  Thromb Res.
  
  Volume: 134 Issue: 4 Pages: 914-917
- DOI
  10.1016/j.thromres.2014.07.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J03741, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-25460683
[Journal Article] Development of a new laboratory test to evaluate antithrombin resistance in plasma.2014
- Author(s)
  Murata M, Takagi A, Suzuki A, Okuyama E, Takagi Y, Ando Y, Kato I, Nakamura Y, Murate T, Matsushita T, Saito H, Kojima T.
- Journal Title
  
  Thromb Res
  
  Volume: 133 Issue: 2 Pages: 293-298
- DOI
  10.1016/j.thromres.2013.11.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-25461445
[Journal Article] Development of new laboratory test to evaluate antithrombin resistance in plasma2014
- Author(s)
  Murata M, Takagi A, Suzuki A, Okuyama E, Takagi Y, Ando Y, Kato I, Nakamura Y, Murate T, Matsushita T, Saito H, Kojima T.
- Journal Title
  
  Thromb Res.
  
  Volume: 133 Pages: 293-299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460683
[Journal Article] Phosphorylated Sp1 is the regulator of DNA-PKcs and DNA ligase IV transcription of daunorubicin-resistant leukemia cell lines2014
- Author(s)
  Nishida Y, Mizutani N, Inoue M, Omori Y, Tamiya-Koizumi K, Takagi A, Kojima T, Suzuki M, Nozawa Y, Minami Y, Ohnishi K, Naoe T, Murate T.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1839 Pages: 265-274
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460674
[Journal Article] A complex genomic abnormality found in a patient with antithrombin deficiency and autoimmune disease-like symptoms.2014
- Author(s)
  Kato I, Takagi Y, Ando Y, Nakamura Y, Murata M, Takagi A, Murate T, Matsushita T, Nakashima T, Kojima T.
- Journal Title
  
  Int J Hematol
  
  Volume: 100 Issue: 2 Pages: 200-205
- DOI
  10.1007/s12185-014-1596-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-25460683, KAKENHI-PROJECT-25461445
[Journal Article] Sphingosine kinase 1 expression is downregulated during differentiation of Friend cells due to decreased c-MYB.2013
- Author(s)
  Mizutani N, Kobayashi M, Sobue S, Ichihara M, Ito H, Tanaka K, Iwaki S,Fujii S,Ito Y, Tamiya-Koizumi K, Takagi A, Kojima T, Naoe T, Suzuki M, Nakamura M, Banno Y, Nozawa Y, Murate T.
- Journal Title
  
  Biochimica et Biophysica Acta -Molecular Cell Research
  
  Volume: 1833 Issue: 5 Pages: 1006-16
- DOI
  10.1016/j.bbamcr.2013.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590139, KAKENHI-PROJECT-23590667, KAKENHI-PROJECT-24590185, KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-24790164
[Journal Article] Ribavirin-induced intracellular GTP depletion activates transcription elongation in coagulation factor VII gene expression2013
- Author(s)
  Suzuki A, Miyawaki Y, Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Takagi A, Murate T, Saito H, Kojima T
- Journal Title
  
  Biochemical J
  
  Volume: 449(1) Pages: 231-239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Ribavirin-induced intracellular GTP depletion activates transcription elongation in coagulation Factor VII gene expression2013
- Author(s)
  Atsuo Suzuki, et al.
- Journal Title
  
  Biochemical Journal
  
  Volume: 449 Issue: 1 Pages: 231-239
- DOI
  10.1042/bj20121286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05159, KAKENHI-PROJECT-22590524
[Journal Article] A novel prothrombin mutation in two families with prominent thrombophilia--the first cases of antithrombin resistance in a Caucasian population.2013
- Author(s)
  Djordjevic V, Kovac M, Miljic P, Murata M, Takagi A, Pruner I, Francuski D, Kojima T, Radojkovic D.
- Journal Title
  
  J Thromb Haemost
  
  Volume: 11 Issue: 10 Pages: 1936-1939
- DOI
  10.1111/jth.12367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25460683
[Journal Article] Establishment of mouse model of MYH9 disorders: heterozygous R702C mutation provokes macrothrombocytopenia with leukocyte inclusion bodies, renal glomerulosclerosis and hearing disability.2013
- Author(s)
  Suzuki N, Kunishima S, Ikejiri M, Maruyama S, Sone M, Takagi A, Ikawa M, Okabe M, Kojima T, Saito H, Naoe T, Matsushita T.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 8 Pages: 41-50
- DOI
  10.1371/journal.pone.0071187
- NAID
  120006957397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591429, KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-24591421, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293129
[Journal Article] Thrombosis from a prothrombin mutation conveying antithrombin resistance2012
- Author(s)
  Miyawaki Y, Suzuki A, Fujita J, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Kunishima S, Sakai M, Okamoto K, Matsushita T, Naoe T, Saito H, Kojima K
- Journal Title
  
  N Engl J Med
  
  Volume: 366 Pages: 2390-2396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Transcriptional regulation of neutral sphingomyelinase 2 in all-trans retinoic acid-treated human breast cancer cell line, MCF-7.2012
- Author(s)
  Ito H
- Journal Title
  
  J Biochem.
  
  Volume: 151 Issue: 6 Pages: 599-610
- DOI
  10.1093/jb/mvs037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790532, KAKENHI-PUBLICLY-23107712, KAKENHI-PROJECT-23590667, KAKENHI-PROJECT-23659664, KAKENHI-PROJECT-24590185, KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-24780125
[Journal Article] Thrombosis from a prothrombin mutation conveying antithrombin resistance.2012
- Author(s)
  Miyawaki Y, Suzuki A, Fujita J, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Kunishima S, Sakai M, Okamoto K, Matsushita T, Naoe T, Saito H, Kojima T
- Journal Title
  
  N Engl J Med.
  
  Volume: 366 Issue: 25 Pages: 2390-2396
- DOI
  10.1056/nejmoa1201994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-22591059, KAKENHI-PROJECT-22591755, KAKENHI-PROJECT-22659114, KAKENHI-PROJECT-23591429
[Journal Article] Role of down-regulated neutral ceramidase during all-trans retinoic acid induced neuronal differentiation in SH-SY5Y neuroblastoma cells2012
- Author(s)
  Kouji Tanaka
- Journal Title
  
  J.Biochem.
  
  Volume: (印刷中) Issue: 6 Pages: 611-620
- DOI
  10.1093/jb/mvs033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790156, KAKENHI-PROJECT-22590139, KAKENHI-PUBLICLY-23107712, KAKENHI-PROJECT-23590667, KAKENHI-PROJECT-23659664, KAKENHI-PROJECT-24590364, KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-24790164
[Journal Article] Thrombosis from a Prothrombin Mutastion Conveying Antithrombin Resistance2012
- Author(s)
  Yuhri Miyawaki, Atsuo Sizuki, Junko Fujita, Asuka Maki, Eriko Okuyama, Moe Murata, Akira Takagi, Takashi Murate, Shinji Kunishima, Michio Sakata, Kohji Okamoto, Tadashi Matsushita, Tomoki Naoe, Hidehiko Saito, Tetsuhito Kojima
- Journal Title
  
  The NEW ENGLAND JOURNAL of MEDICINE
  
  Volume: 366巻 Pages: 2390-2396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659114
[Journal Article] A novel ENG mutation causing impaired co-translational processing of endoglin associated with hereditary hemorrhagic telangiectasia.2012
- Author(s)
  Suzuki A, Nakashima D, Miyawaki Y, Fujita J, Maki A, Fujimori Y, Takagi A, Murate T, Teranishi M, Matsushita T, Saito H, Kojima T
- Journal Title
  
  Thromb Res
  
  Volume: 129(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] A possible mechanismfor Inv22-related F8 large deletions in severe hemophilia A patients with high responding factor VIII inhibitors2012
- Author(s)
  J. Fujita, Y. Miyawaki, A. Suzuki, et al.
- Journal Title
  
  Journal of Thrombosis and Haemostasis
  
  Volume: 10 Issue: 10 Pages: 2099-2107
- DOI
  10.1111/j.1538-7836.2012.04897.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05159, KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-22591059
[Journal Article] A novel ENG mutation causing impaired co-translational processing of endoglin associated with hereditary hemorrhagic telangiestasia2012
- Author(s)
  Atsuo Suzuki
- Journal Title
  
  Thrombosis Research
  
  Volume: (in press) Issue: 5 Pages: e200-e208
- DOI
  10.1016/j.thromres.2011.12.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05159, KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-22591059
[Journal Article] A possible mechanism for Inv22-related F8 large deletions in severe hemophilia a patients with high responding factor VIII inhibitors2012
- Author(s)
  Fujita J, Miyawaki Y, Suzuki A, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Suzuki N, Matsushita T, Saito H, Kojima T
- Journal Title
  
  J Thromb Haemost
  
  Volume: 10(10) Pages: 2099-2107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation2010
- Author(s)
  Y Miyawaki, A Suzuki, Y Fujimori, A Takagi, T Murate, N Suzuki, A Katsumi, T Naoe, K Yamamoto, T Matsushita, J Takamatsu, T Kojima
- Journal Title
  
  Int J Hematol
  
  Volume: 92(2) Pages: 405-408
- NAID
  10026712691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] A novel splice site mutation in intron C of PROS1 leads to markedly reduced mutant mRNA level, absence of thrombin-sensitive region, and impaired secretion and cofactor activity of mutant protein S.2010
- Author(s)
  H Okada, S Kunishima, M Hamaguchi, A Takagi, K Yamamoto, J Takamatsu, T Matsushita, H Saito, T Kojima, T Yamazaki
- Journal Title
  
  Thromb Res
  
  Volume: 125(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Activated protein C resistance in the Japanese population due to homozygosity for the factor V R2 haplotype2010
- Author(s)
  H Okada, Y Toyoda, A Takagi, H Saito, T Kojima, T Yamazaki
- Journal Title
  
  Int J Hematol
  
  Volume: 91(3) Pages: 549-550
- NAID
  10026401575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Down-regulation of PROS1 gene expression by 17.-estradiol via estrogen receptor . (ER.)-Sp1 interaction recruiting receptor-interacting protein140 and the corepressor-HDAC3 complex.2010
- Author(s)
  A Suzuki, N Sanda, Y Miyawaki, Y Fujimori, T Yamada, A Takagi, T Murate, H Saito, T Kojima
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285(18) Pages: 13444-13453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] T Murate : Implications of sphingosine kinase 1 expression level for the cellular sphingolipid rheostat: relevance as a marker for daunorubicin sensitivity of leukemia cells2008
- Author(s)
  S Sobue, S Nemoto, M Murakami, H Ito, A Kimura, S Gao, A Furuhata, A Takagi, T Kojima, M Nakamura, M Ito, M Suzuki, Y Banno, Y Nozawa
- Journal Title
  
  Int J Hematol 87(3)
  
  Pages: 266-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] v-Src oncogene product increases sphingosine kinase 1 expression through mRNA stabilization: alteration of AU-rich element-binding proteins2008
- Author(s)
  S Sobue, M Murakami, Y Banno, H Ito, A Kimura, S Gao, A Furuhata, A Takagi, T Kojima, M Suzuki, Y Nozawa, T Murate
- Journal Title
  
  Oncogene 27(46)
  
  Pages: 6023-6033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Molecular Defects Associated with Antithrombin Deficiency and Dilated Cardiomyopathy in a Japanese Patient2008
- Author(s)
  Y Fujimori, H Okimatsu, T Kashiwagi, N Sanda, K Okumura, A Takagi, K Nagata, T Murate, A Uchida, K Node, H Saito and T Kojima
- Journal Title
  
  Inter Med. 47(10)
  
  Pages: 925-931
- NAID
  130000078680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] A neonate with homozygous protein C deficiency with a homozygous Arg178Trp mutation2008
- Author(s)
  F Ozlu, M Kyotani, E Taskin, K Ozcan, T Kojima, T Matsushita, H Yapicioglu, A Takagi, I Sasmaz, M Satar, and N Narli
- Journal Title
  
  J Pediatr Hematol Oncol 30
  
  Pages: 608-611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] L1503R is a member of group I mutation and has dominant-negative effect on secretion of full-length VWF multimers: an analysis of two patients with type 2A von Willebrand disease.2008
- Author(s)
  T Kashiwagi, T Mstsushita, Y Ito, K Hirashima, N Sanda, Y Fujimori, T Yamada, K Okumura, A Takagi, T Murate, A Katsumi, J Takamatsu, K Yamamoto, T Naoe, T Kojima
- Journal Title
  
  Haemophilia 14(3)
  
  Pages: 556-563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Skewed X chromosome inactivation in fraternal female twins results in moderately severe and mild haemophilia B2008
- Author(s)
  K Okumura, Y Fujimori, A Takagi, T Murate, M Ozeki, K Yamamoto, A Katsumi, T Matsushita, T Naoe, and T Kojima
- Journal Title
  
  Haemophilia 14(5)
  
  Pages: 1088-1093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] An Sp1 binding site mutation of the PROS1 promoter in a patient with protein S deficiency2007
- Author(s)
  N Sanda, Y Fujimori, T Kashiwagi, A Takagi, T Murate, E Mizutani, T Matsushita, T Naoe, T Kojima
- Journal Title
  
  Br J Haematol 138(5)
  
  Pages: 663-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Wilms' tumor 1 message and protein expression in bone marrow failure syndrome and acute leukemia2007
- Author(s)
  T Iwasaki, C Sugisaki, K Nagata, K Takagi, A Takagi, T Kojima, M Ito, S Nakamura, T Naoe, T Murate
- Journal Title
  
  Pathol Int 57(10)
  
  Pages: 645-651
- NAID
  10021233832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] RET signaling-induced SPHK1 gene expression plays a role in both GDNF-induced differentiation and MEN2-type oncogenesis2007
- Author(s)
  Murakami, M Ichihara, S Sobue, R Kikuchi, H Ito, A Kimura, T Iwasaki, A Takagi, T Kojima, M Takahashi, M Suzuki, Y Banno, Y Nozawa, T Murate1
- Journal Title
  
  J Neurochem 102(5)
  
  Pages: 1585-1594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Mechanism of vitamin D3-induced transcription of phospholipase D1 in HaCat human keratinocytes2007
- Author(s)
  R Kikuchi, S Sobue, M Murakami, H Ito, A Kimura, T Iwasaki, S Shibayama, A Takagi, T Kojima, M Suzuki, Y Banno, Y Nozawa, T Murate
- Journal Title
  
  FEBS Lett 581(9)
  
  Pages: 1800-1804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Molecular basis of antithrombin deficiency in four Japanese patients with antithrombin gene abnormalities including two novel mutations2007
- Author(s)
  M Kyotani, K Okumura, A Takagi, T Murate, K Yamamoto, T Matsushita, M Sugimura, N Kanayama, T Kobayashi, H Saito, T Kojima
- Journal Title
  
  Am J Hematol 82(2)
  
  Pages: 702-705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Transcription factor specificity protein 1 (Sp1) is the main regulator of nerve growth factor-induced sphingosine kinase 1 gene expression of the rat pheochromocytoma cell line, PC12.2005
- Author(s)
  Sobue S, Hagiwara K, Banno Y, Tamiya-Koizumt K, Suzuki M, Takagi A, Kojima T, Asano H, Nozawa Y, Murate T.
- Journal Title
  
  J Neurochem. 95(4)
  
  Pages: 940-949
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590453
[Patent] 血栓症のリスク検査法2013
- Inventor(s)
  高木明、小嶋哲人、高木夕希、村田萌
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-182541
- Filing Date
  2013-09-03
- Data Source
  KAKENHI-PROJECT-25293129
[Patent] 凝固因子として作用する異常トロンビンのためのトロンビン不活化動態測定方法2013
- Inventor(s)
  高木　明、小嶋哲人、松下　正
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-04-01
- Acquisition Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-25293129
[Patent] 血栓症のリスク検査法2013
- Inventor(s)
  高木明、小嶋哲人、高木夕希、村田萌
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-07-17
- Data Source
  KAKENHI-PROJECT-25460683
[Patent] 凝固因子として作用する異常トロンビンのためのトロンビン不活化動態測定方法及び試験方法、並びに、ポリヌクレオチド2010
- Inventor(s)
  高木明, 小嶋哲人, 松下正
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Number
  2010-289686
- Filing Date
  2010-12-27
- Data Source
  KAKENHI-PROJECT-22659114
[Patent] 凝固因子として作用する異常トロンビンのためのトロンビン不活化動態測定方法及び試験方法、並びに、ポリヌクレオチド2010
- Inventor(s)
  高木明, 小嶋哲人, 松下正
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Industrial Property Number
  2010-289686
- Filing Date
  2010-12-27
- Data Source
  KAKENHI-PROJECT-22590524
[Patent] 凝固因子として作用する異常トロンビンのためのトロンビン不活化動態測定方法及び試験方法、並びに、ポリヌクレオチド2010
- Inventor(s)
  高木明、小嶋哲人、松下正
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Filing Date
  2010-12-27
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] Many of the prothrombin mutations in the sodium-binding region cause an antithrombin- resistance phenotype2018
- Author(s)
  Shogo Tamura, Moe Murata-Kawakami, Yuki Takagi, Sachiko Suzuki, Akira Katsumi, Akira Takagi, Tetsuhito Kojima
- Organizer
  第40回日本血栓止血学会学術集会学術推進委員会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] 血液凝固第V因子欠乏症を合併する血友病 A 症例:第2報・凝血学的評価2018
- Author(s)
  鈴木幸子,高木夕希,坂根寛人,橋本恵梨華,垣原美紗樹,服部有那,大平晃也,所真昼,田村彰吾,高木明,鈴木敦夫,鈴木伸明,松下正,山崎鶴夫,小嶋哲人
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] 血漿検体測定を目指したアンチトロンビン抵抗性凝固第X因子検出法の構築2018
- Author(s)
  田村彰吾,高木明,藤岡亮也,服部有那,垣原美紗樹,高木夕希,鈴木幸子,高木夕希,小嶋哲人
- Organizer
  第19回日本検査血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] F8 Inv22を含む複雑な変異を同定した重症血友病A症例の遺伝学的変異アレル由来の検索2018
- Author(s)
  垣原美紗樹,田村彰吾,服部有那,高木夕希,鈴木幸子,橋本恵梨華,坂根寛人,大平晃也,所真昼,高木明,小川実加,兼松毅,鈴木伸明,松下正,小嶋哲人
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Functional analysis of a variant fibrinogen from dysfibrinogenemia patient with cerebral2018
- Author(s)
  Yuna Hattori, Takagi Yuki, Misaki Kakihara, Sachiko Suzuki, Koya Odaira, Mahiru Tokoro, Shogo Tamura, Tsuyoshi Kanemetsu, Nobuaki Suzuki, Tadashi Matsushita, Tetsuhito Kojima
- Organizer
  The 10th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Antithrombin resisitance 検査法の改良：Bovine FXa/Va prothrombin activator システムの構築と血液凝固分析装置適応条件の検討2018
- Author(s)
  田村彰吾，川上萌，垣原美紗樹，服部有那，鈴木幸子，高木夕希，高木明，小嶋哲人
- Organizer
  第12 回日本血栓止血学会学術標準化委員会（SSC）シンポジウム
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] 血漿検体測定を目指したアンチトロンビン抵抗性凝固第X因子検出法の構築2018
- Author(s)
  田村彰吾、高木明、藤岡亮也、服部有那、垣原美紗樹、鈴木幸子、高木夕希、小嶋哲人
- Organizer
  第19回日本検査血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] 特発生血栓 : アンチトロンビン抵抗性の診断－凝検査法を中心に－2018
- Author(s)
  高木明,田村彰吾,小嶋哲人
- Organizer
  第19回日本検査血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] スプライシング異常を引き起こす血液凝固第IX遺伝子サイレント変異・血友病B分子病態2018
- Author(s)
  大平晃也,田村彰吾,坂根寛人,所真昼,垣原美紗樹,服部有那,橋本恵梨華,鈴木幸子,高木夕希,高木明,兼松毅,岸本麻由子,鈴木伸明,松下正,小嶋哲人
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] 脳梗塞を発症したフィブリノケゲン異常症の分子病態機能解析2018
- Author(s)
  服部有那,垣原美紗樹,高木夕希,鈴木幸子,橋本恵梨華,坂根寛人,大平晃也,所真昼,田村彰吾,高木明,鈴木伸明,松下正,小嶋哲人
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] アンチトロンビン抵抗性の診断 -検査法を中心に-2018
- Author(s)
  高木明、田村彰吾、小嶋哲人
- Organizer
  第19回日本検査血液学会学術集会シンポジウム1 特発性血栓症
- Invited
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] アンチトロンビン抵抗性凝固第 Xa 因子検出法の開発2017
- Author(s)
  藤岡亮也、中田悠紀子、坂根寛人、橋本恵梨華、河村奈美、槇山愛弓、鈴木幸子、高木夕希、田村彰吾、高木明、小嶋哲人
- Organizer
  第39回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] Thrombin generation assay CANNOT identify antithrombin resistance during anticoagulant therapy2017
- Author(s)
  Yuki Takagi, Sachiko Suzuki, Nami Kawamura, Ayumi Makiyama, Hiroto Sakane, Erika Hashimoto, Akiya Fujioka, Shogo Tamura, Akira Takagi, Valentina Djordjevic, Tetsuhito Kojima
- Organizer
  XXVI Congress of International Society on Thrombosis and Haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Assessment of F9 mutation associated with inhibitor development in Japanese hemophilia B patients2017
- Author(s)
  Hiroto Sakane, Shogo Tamura, Erika Hashimoto, Akiya Fujioka, Ayumi Makiyama, Nami Kawamura, Sachiko Suzuki, Yuki Takagi, Tsuyoshi Kanematsu, Mayuko Kishimoto, Mika Ogawa, Nobuaki Suzuki, Tadashi Matsushita, Hiroshi Yada, Midori Shima, Tetsuhito Kojima
- Organizer
  XXVI Congress of International Society on Thrombosis and Haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] アンチトロンビン抵抗性はトロンビン生成試験(TGA)により検出可能か2017
- Author(s)
  高木夕希、鈴木幸子、河村奈美、槇山愛弓、坂根寛人、橋本恵梨華、藤岡亮也、田村彰吾、高木明、小嶋哲人
- Organizer
  第39回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] Unusual Genomic Rearrangement combined with Inv22 and wild-type X-chromosome in severe hemophilia A patients2017
- Author(s)
  Shogo Tamura, Misaki Kakihara, Yuna Hattori, Erika Hashimoto, Hiroto Sakane, Yuki Takagi, Mika Ogawa, Takeshi Kanematsu, Nobuaki Suzuki, Akira Takagi, Tadashi Matsushita, Tetsuhito kojima
- Organizer
  XXVI Congress of International Society on Thrombosis and Haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Thrombin generation assay CANNOT identify antithrombin resistance during anticoagulant therapy2017
- Author(s)
  Yuki Takagi, Sachiko Suzuki, Nami Kawamura Ayumi Makiyama, Hiroto Sakane, Erika Hashimoto, Akiya Fujioka, Shogo Tamura, Akira Takagi, Tetsuhito Kojima
- Organizer
  XXVI Congress of International Society on Thrombosis and Haemostasis,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] Compound heterozygosity for mutations in ITGA2B including a novel p.Cys198Ser in Glanzmann Thrombasthenia2017
- Author(s)
  Erika Hashimoto, Shinji Kunishima, Yuki Takagi, Sachiko Suzuki, Ayumi Makiyama, Hiroto Sakane, Akiya Fujioka, Takahiro Uehara, Shogo Tamura, Akira Takagi, Tetsuhito kojima
- Organizer
  XXVI Congress of International Society on Thrombosis and Haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Molecular basis of F8 gene abnormality in hemophilia A patients in Nagoya2016
- Author(s)
  Nami KAWAMURA, Ayumi MAKIYAMA, Yuki TAKAGI, Erika HASHIMOTO, Hiroto SAKANE, Akiya FUJIOKA, Shogo TAMURA, Akira TAKAGI, Nobuaki SUZUKI, Tadashi MATSUSHITA, Tetsuhito KOJIMA
- Organizer
  The 9th Congress of Asia Pacific Society of Thrombosis and Hemostasis (APSTH)
- Place of Presentation
  Taipei
- Year and Date
  2016-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] プロテインC欠乏症51家系のPROC遺伝子解析2016
- Author(s)
  槇山愛弓、高木夕希、河村奈美、橋本恵梨華、田村彰吾、高木明、岸本磨由子、鈴木伸明、松下正、小嶋哲人
- Organizer
  第17回日本検査血液検査血液学会学術集会
- Place of Presentation
  博多
- Year and Date
  2016-08-06
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] A NOVEL LARGE DELETION FOUND IN A JAPANESE FAMILY WITH ANTITHROMBIN DEFICIENCY2016
- Author(s)
  Erika HASHIMOTO, Yuki TAKAGI, Nami KAWAMURA, Ayumi MAKIYAMA, Hiroto SAKANE, Akiya FUJIOKA, Shogo TAMURA, Akira TAKAGI, Yoshifumi FUKUSHIMA, Makoto KANEKO, Tetsuhito KOJIMA
- Organizer
  The 9th Congress of Asia Pacific Society of Thrombosis and Hemostasis (APSTH)
- Place of Presentation
  Taipei
- Year and Date
  2016-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] プロトロンビンArg596ミスセンス変異がトロンビンのトロンボモジュリン結合能に及ぼす影響2016
- Author(s)
  高木夕希, 河村奈美, 槇山愛弓, 橋本恵梨華, 田村彰吾, 高木明, 小嶋哲人
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] 低フィブリノゲン血症3症例の遺伝子解析2016
- Author(s)
  高木夕希、河村奈美、槇山愛弓、橋本恵梨華、安藤裕実、加藤衣央、田村彰吾、高木明、小嶋哲人
- Organizer
  第38回日本血栓止血学会学術集会
- Place of Presentation
  奈良
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Prothrombin missense mutations at 596Arg reduced the affinity of mutant thrombin to thrombomodulin controlled by Na+ concentration.2016
- Author(s)
  Yuki Takagi, Nami Kawamura, Ayumi Makiyama, Erika Hashimoto, Shogo Tamura, Akira Takagi, Tetsuhito Kojima
- Organizer
  XXIX International Symposium on Technical Innovations in Laboratory Hematology (ISLH)
- Place of Presentation
  Milano, Italy
- Year and Date
  2016-05-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Prothrombin missense mutations at 596Arg reduced the affinity of mutant thrombin to thrombomodulin controlled by Na+ concentration2016
- Author(s)
  Yuki Takagi, Nami Kawamura, Ayumi Makiyama, Erika Hashimoto, Shogo Tamura, Akira Takagi, Tetsuhito Kojima
- Organizer
  XXIX International Symposium on Technical Innovations in Laboratory Hematology
- Place of Presentation
  Milano
- Year and Date
  2016-05-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] Analysis of prothrombin mutants in NA+ binding domain as a potential candidate conveying antithrombin resistance2015
- Author(s)
  Moe Murata, Naoki Mizutani, Yuki Takagi, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Tetsuhito Kojima
- Organizer
  XXV Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] Practical laboratory assay to detect abnormal prothrombin conveying thrombomodulin resistance2015
- Author(s)
  高木夕希、水谷直貴、村田萌、小塚敏弘、中田悠紀子、長谷部瞭、河村奈美、槇山愛弓、橋本恵梨華、高木明、小嶋哲人高木夕希、水谷直貴、村田萌、小塚敏弘、中田悠紀子、長谷部瞭、河村奈美、槇山愛弓、橋本恵梨華、高木明、小嶋哲人
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] アンチトロンビン抵抗性検出検査法の自動凝固検査機器への最適化 Part 22015
- Author(s)
  村田　萌、水谷直貴、高木夕希、長谷部瞭、小塚敏弘、中田悠紀子、高木　明、松下　正、小嶋哲人
- Organizer
  第16回日本検査血液検査血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] Investigation of molecular mechanisms of PS mRNA up-regulation by progestin isoforms in HepG2 cells.2015
- Author(s)
  小塚敏弘、長谷部瞭、中田悠紀子、槇山愛弓、河村奈美、中村友紀、高木夕希、村田萌、水谷直貴、高木明、小嶋哲人
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] 先天性アンチトロンビン欠乏症８症例SERPINC1遺伝子解析2015
- Author(s)
  中田悠紀子、小塚敏弘、長谷部瞭、高木夕希、村田萌、上牧務、松尾真稔、高木明、松下正、小嶋哲人
- Organizer
  第16回日本検査血液検査血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] ロトロンビン変異による新たなアンチトロンビン抵抗性変異の候補解析2015
- Author(s)
  村田萌、水谷直貴、高木夕希、長谷部瞭、小塚敏弘、中田悠紀子、槇山愛弓、河村奈美、橋本恵梨華、高木明、松下正、小嶋哲人
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] 深部静脈血栓症で発症しアンチトロンビン抵抗性を示した本邦初 Prothrombin Belgrade 変異の一家系2015
- Author(s)
  岸本磨由子、鈴木伸明、村田萌、小川実加、兼松毅、高木明、小嶋哲人、松下正
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] A case of severe hemophilia B associated with a large insertion of SVA RETROTRANSPOSON in the coagulation factor IX gene.2015
- Author(s)
  Naoki Mizutani, Yuki Nakamura, Moe Murata, Yuki Takagi, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Jun-ichi Kitazawa, Midori Shima, Tetsuhito Kojima
- Organizer
  XXV Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-06-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] Analysis of prothrombin mutants in NA+ binding domain as a potential candidate conveying antithrombin resistance.2015
- Author(s)
  Moe Murata, Naoki Mizutani, Yuki Takagi, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Tetsuhito Kojima
- Organizer
  XXV Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-06-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] Analysis of prothrombin missense mutants at 596ARG by single nucleotide substitution for anticoagulant system.2015
- Author(s)
  Yuki Takagi, Moe Murata, Yuki Nakamura, Toshihiro Kozuka, Yukiko Nakata, Ryo Hasebe, Akira Takagi, Tetsuhito Kojima
- Organizer
  XXV Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-06-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] 深部静脈血栓症で発症したアンチトロンビンレジスタンス症例の抗凝固療法2015
- Author(s)
  岸本磨由子、鈴木伸明、村田萌、小川実加、兼松毅、高木明、小嶋哲人、松下正
- Organizer
  第16回日本検査血液検査血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] プロトロンビン変異による新たなアンチトロンビン抵抗性変異の候補解析2015
- Author(s)
  村田　萌、水谷直貴、高木夕希、長谷部瞭、小塚敏弘、中田悠紀子、槇山愛弓、河村奈美、橋本恵梨華、高木　明、松下　正、小嶋哲人
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] A congenital dysprothrombinemia with both decreased prothrombin activity and antithrombin resistance2015
- Author(s)
  高田麻央、森下英里子、谷口文苗、關口暁子、小林英里奈、朝倉英策、高木明、小嶋哲人、大竹茂樹
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] プロトロンビン Arg596 における一塩基置換ミスセンス変異体のトロンボモジュリン抵抗性評価2015
- Author(s)
  高木夕希、村田　萌、中村友紀、小塚敏弘、中田悠紀子、長谷部瞭、橋本恵梨華、高木　明、小嶋哲人
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] プロトロンビンArg596 における一塩基置換ミスセンス変異体のトロンボモジュリン抵抗性評価2015
- Author(s)
  高木夕希、村田萌、中村友紀、小塚敏弘、中田悠紀子、長谷部瞭、橋本恵梨華、高木明、小嶋哲人
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] Analysis of prothrombin missense mutants at 596ARG by single nucleotide substitution for anticoagulant system2015
- Author(s)
  Yuki Takagi, Moe Murata, Yuki Nakamura, Toshihiro Kozuka, Yukiko Nakata, Ryo Hasebe, Akira Takagi, Tetsuhito Kojima
- Organizer
  XXV Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] 深部静脈血栓症で発症しアンチトロンビン抵抗性を示した本邦初 Prothrombin Belgrade 変異の一家系2015
- Author(s)
  岸本磨由子、鈴木伸明、村田萌、小川実加、兼松毅、高木明、小嶋哲人、松下正
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] 先天性アンチトロンビン欠乏症８症例SERPINC1遺伝子解析2015
- Author(s)
  中田悠紀子、小塚敏弘、長谷部瞭、高木夕希、村田　萌、上牧　務、松尾真稔、高木　明、松下　正、小嶋哲人
- Organizer
  第16回日本検査血液検査血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] 血小板無力症に同定された GPIIb 遺伝子のミスセンス変異とスプライス変異の複合ヘテロ変異解析2015
- Author(s)
  橋本恵梨華、村田萌、槇山愛弓、河村奈美、小塚敏弘、中田悠紀子、長谷部瞭、高木夕希、水谷直貴、高木明、國島伸治、松下正、小嶋哲人
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] Practical laboratory assay to detect abnormal prothrombin conveying thrombomodulin resistance.2015
- Author(s)
  高木夕希、水谷直貴、村田萌、小塚敏弘、中田悠紀子、長谷部瞭、河村奈美、槇山愛弓、橋本恵梨華、高木明、小嶋哲人
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] 深部静脈血栓症で発症したアンチトロンビンレジスタンス症例の抗凝固療法2015
- Author(s)
  岸本磨由子、鈴木伸明、村田　萌、小川実加、兼松　毅、高木　明、小嶋哲人、松下　正
- Organizer
  第16回日本検査血液検査血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] アンチトロンビン抵抗性検出検査法の自動凝固検査機器への最適化 Part 22015
- Author(s)
  村田萌、水谷直貴、高木夕希、長谷部瞭、小塚敏弘、中田悠紀子、高木明、松下正、小嶋哲人
- Organizer
  第16回日本検査血液検査血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] 原因不明であった静脈血栓塞栓症にみられたアンチトロンビン抵抗性を示す本邦２家系目のプロトロンビン異常症2014
- Author(s)
  村田　萌、高木夕希、中村友紀、長谷部　瞭、小塚敏弘、中田　悠紀子、高木　明、村手　隆、松下　正、小嶋哲人
- Organizer
  第33回日本臨床検査医学会東海・北陸支部例会
- Place of Presentation
  名古屋大学鶴舞キャンパス
- Year and Date
  2014-08-02
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] アンチトロンビン抵抗性の関与が疑われた家族性再発性肺血栓塞栓症の1例2014
- Author(s)
  吉田　律、角田　聖子、長谷川　潤、大木　理次、武本　知之、小山　達也、山崎　弘二、関　晋吾、吉村　道博、高木　明、小嶋　哲人
- Organizer
  第233回日本循環器学会関東・甲信越地方会
- Place of Presentation
  東京
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] 原因不明であった静脈血栓塞栓症にみられたアンチトロンビン抵抗性を示す本邦２家系目のプロトロンビン異常症2014
- Author(s)
  村田　萌、高木　明、岸本磨由子、清井　仁、松下　正、小嶋哲人
- Organizer
  第33回日本臨床検査医学会東海・北陸支部例会
- Place of Presentation
  名古屋
- Year and Date
  2014-08-02
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] Regulatory mechanism of SPHK2 expresssion in colon cancer cell lines2013
- Author(s)
  Mizutani N, Inoue M, Nishida Y, Omori Y, Suzuki M, Koizumi K, Takagi A, Kojima T, Iwaki S, Fujii S, Nakamura M, Banno Y, Nozawa Y, Murate T
- Organizer
  7^<th> International Conference of Ceramide
- Place of Presentation
  Montauk, NY. USA
- Year and Date
  2013-10-21
- Data Source
  KAKENHI-PROJECT-23590667
[Presentation] A clinical laboratory test detecting antithrombin resistance of the new thrombophilia2013
- Author(s)
  MURATA Moea, TAKAGI Akira, SUZUKI Atsuo,TAKAGI Yuki, KATO Io, ANDO Yumi, MURATE Takashi, MATSUSHITA Tadashi, SAITO Hidehiko, KOJIMA Tetsuhito
- Organizer
  XXIV Congress of International Society on Thrombosis and Haemostasis,
- Place of Presentation
  Amsterdam, The Neterlands
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] アンチトロンビン抵抗性解析法の改良と評価2013
- Author(s)
  村田　萌、高木　明、中村友紀、加藤衣央、安藤裕実、高木夕希、村手　隆、松下　正、小嶋哲人
- Organizer
  第14回日本検査血液検査血液学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] The mechanism of cytotoxicity by resveratrol against human leukemia cell lines2013
- Author(s)
  Omori Y, Mizutani N, Inoue M, Nishida Y, Suzuki M, Koizumi K, Takagi A, Kojima T, Iwaki S, Fujii S, Nakamura M, Nozawa Y, Murate T
- Organizer
  7^<th> International Conference of Ceramide
- Place of Presentation
  Montauk, NY. USA
- Year and Date
  2013-10-22
- Data Source
  KAKENHI-PROJECT-23590667
[Presentation] プロトロンビンYukuhashi由来変異型トロンビンのトロンボモジュリン・プロテインC系に及ぼす影響2013
- Author(s)
  高木夕希、高木　明、鈴木敦夫、奥山恵理子、村田　萌、加藤衣央、安藤裕実、中村友紀、松下　正、齋藤英彦、小嶋哲人
- Organizer
  第14回日本検査血液検査血液学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] Effects of prothrombin Yukuhashi mutation on thrombomodulin-protein C system2013
- Author(s)
  TAKAGI Yuki, KAT O Io, ANDO Yumi, MURATA Moea, SUZUKI Atsuo, TAKAGI Akira, MATSUSHITA Tadashi, SAITO Hidehiko, KOJIMA Tetsuhito
- Organizer
  XXIV Congress of International Society on Thrombosis and Haemostasis,
- Place of Presentation
  Amsterdam, The Neterlands
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] 静脈血栓塞栓症リスク・アンチトロンビン抵抗性とそのスクリーニング検査2012
- Author(s)
  高木明、宮脇由理、鈴木敦夫、藤田絢子、牧明日加、奥山恵理子、村田萌、村手隆、松下正、小嶋哲人
- Organizer
  第34回日本血栓止血学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659114
[Presentation] Up-regulation mechanisms of syndecan-4, a heparan sulfate proteoglycan, expression by TNF-a in human endothelial like EAhy926 cells2012
- Author(s)
  Okuyama E, Murata M, Suzuki A, Ando Y, Kato I, Takagi Y, Takagi A, Murate T, Saito T, Kojima T
- Organizer
  第35回日本分子生物学会年
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] Molecular mechanisms of syndecan-4 upregulation by TNF-. in the endothelial-like EAhy926 cells2012
- Author(s)
  Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Miyawaki Y, Suzuki A, Takagi A, Murate T, Saito T, Kojima T
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] 静脈血栓症リスク・アンチトロンビン抵抗性とそのスクリーニング検査法2012
- Author(s)
  高木明
- Organizer
  第34回日本血栓止血学会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-22659114
[Presentation] A Possible Mechanism for Inv22-related F8 Large Deletions in Severe Hemophilia A Patients with High Responding Factor VIII Inhibitors.2012
- Author(s)
  Fujita J, Miyawaki Y, Suzuki A, Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Hosaka M, Takagi A, Murate T, Kajiura Y, Suzuki N, Matsushita T, Saito H, Kojima T
- Organizer
  VIIth Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Place of Presentation
  Meibourun, Australia
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] A Possible Mechanism for Inv22-related F8 Large Deletions in Severe Hemophilia A Patients with High Responding Factor VIII Inhibitors2012
- Author(s)
  Fujita J, Miyawaki Y, Suzuki A, Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Hosaka M, Takagi A, Murate T, Kajiura Y, Suzuki N, Matsushita T, Saito T, Kojima T
- Organizer
  VIIth Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] NF-kappaB is essential for Syndecan-4 up-regulation by TNF-alpha in Vascular Endothelial-like EAhy926 Cells2012
- Author(s)
  Okuyama E, Murata M, Suzuki A, Miyawaki Y, Ando Y, Kato I, Takagi Y, Takagi A, Murate T, Saito T, Kojima T
- Organizer
  VIIth Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] 静脈血栓塞栓症リスク・アンチトロンビン抵抗性とそのスクリーニング検査法2012
- Author(s)
  高木明
- Organizer
  日本血栓止血学会
- Place of Presentation
  ハイアットリージェンシー東京(東京都)(発表確定)
- Year and Date
  2012-06-08
- Data Source
  KAKENHI-PROJECT-22659114
[Presentation] Immunosuppressant IMP dehydrogenase inhibitors up-regulated coagulation factor VII mRNA2012
- Author(s)
  Suzuki A, Miyawaki Y, Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Takagi A, Murate T, Saito T, Kojima T
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] Molecular Basis of Coagulation Factor IX Gene Abnormalities in 16 Japanese Hemophilia B Patients2012
- Author(s)
  Murata M, Okuyama E, Suzuki A, Miyawaki Y, Ando Y, Kato I, Takagi Y, Hosaka M, Takagi A, Murate T, Kishimoto, M, Suzuki N, Matsushita T, Saito T, Kojima T
- Organizer
  VIIth Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] アンチトロンビン抵抗性解析法とその評価2011
- Author(s)
  高木明
- Organizer
  日本臨床検査医学会
- Place of Presentation
  岡山コンベンションセンター(岡山県)
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-22659114
[Presentation] アンチトロンビン抵抗性解析法とその評価2011
- Author(s)
  高木明、宮脇由理、鈴木敦夫、藤田絢子、牧明日加、奥山恵理子、村田萌、村手隆、松下正、小嶋哲人
- Organizer
  第58回日本臨床検査医学会学術集
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22659114
[Presentation] PS-1-72: Unusual X-chromosomal rearrangements with F8-int22 inversion in three severe hemophilia A patients2011
- Author(s)
  Fujita J, Miyawaki Y, Suzuki A, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Matsushita T, Suzuki N, Saito H, Kojima T
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] A NOVEL PROTHROMBIN GENE MUTATION LEADS TO AN AT-RESISTANT THROMBIN IN A FAMILY WITH INHERITED THROMBOPHILIA2011
- Author(s)
  Miyawaki Y, Suzuki A, Fujimori Y, Fujita J, Maki A, Takagi A, Murate T, Sakai M, Okamoto K, Matsushita T, Kojima T
- Organizer
  XXIIIrd Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] A novel prothrombin gene mutation leads to an at-resistant thrombin in afamily with inherited thrombophilia2011
- Author(s)
  Miyawaki Y, Suzuki A, Fujimori Y, Fujita J, Maki A, Takagi A, Murate T, Sakata M, Okamoto K, Matsushita T, Kojima T
- Organizer
  XXIIIth CONGRESS OF THE INTERNATIONAL SOCIETY ON THROMBOSIS AND HAEMOSTASIS
- Place of Presentation
  KYOTO
- Data Source
  KAKENHI-PROJECT-22659114
[Presentation] アンチトロンビン抵抗性を検出するトロンビン不活化動態解析法の開発2011
- Author(s)
  高木明
- Organizer
  日本検査血液学会
- Place of Presentation
  川崎医療福祉大学(岡山県)
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-22659114
[Presentation] PS-1-63: Thrombophilia and JAK2 V617F mutations in Japanese patients with Budd-Chiari syndrome2011
- Author(s)
  Maki A, Fujita J, Okuyama E, Murata M, Miyawaki Y, Suzuki A, Takagi A, Murate T, Kojima T
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] OS-3-120: Molecular basis of an AT-resistant variant thrombin found in a Japanese family with thrombophilia2011
- Author(s)
  Miyawaki Y, Suzuki A, Fujita J, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Kunishima S, Sakai M, Okamoto K, Matsushita T, Kojima T
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] アンチトロンビン抵抗性を検出するトロンビン不活化動態解析法の開発2011
- Author(s)
  高木明、宮脇由理、鈴木敦夫、藤田絢子、牧明日加、奥山恵理子、村田萌、村手隆、松下正、小嶋哲人
- Organizer
  12回日本検査血液学会学術集会
- Place of Presentation
  倉敷
- Data Source
  KAKENHI-PROJECT-22659114
[Presentation] DISTINCT X-CHROMOSOMAL REARRANGEMENTS WITH F8-INTRON22 INVERSION IN THREE UNRELATED JAPANESE SEVERE HEMOPHILIA A PATIENTS WITH HIGH TITER INHIBITOR2011
- Author(s)
  Fujita J, Suzuki A, Miyawaki Y, Maki A, Fujimori Y, Takagi A, Murate T, Matsushita T, Suzuki N, Saito H, Kojima T
- Organizer
  XXIIIrd Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] Receptor interacting protein 140 (RIP140) mediated ERα-Sp1 and corepressor-HDAC3 complex association in 17β-estradiol dependent down-regulation of protein S2010
- Author(s)
  A Suzuki, Y Miyawaki, J Fujita, A Maki, Y Fujimori, A Takagi, T Murate, H Saito, T Kojima
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] A novel endoglin gene mutation associated with hereditary hemorrhagic telangiectasia in a Japanese2010
- Author(s)
  A Suzuki, Y Miyawaki, J Fujita, A Maki, Y Fujimori, A Takagi, T Murate, M Teranishi, H Saito, T Kojima
- Organizer
  第72回日本血液学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] 新規Gr cm pI 変異L1503R のv cm Wi11ebrand病type2A発症における役割2008
- Author(s)
  平島寛司、柏木隆宏、松下正、伊藤康友、高木明、村手隆、勝見章、直江知樹、小嶋哲人
- Organizer
  第31回日本血栓止血学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 新規Group I 変異L1503R のvonWillebrand 病type 2A発症における役割2008
- Author(s)
  柏木隆宏、松下正、伊藤康友、高木明、村手隆、勝見章、平島寛司、直江知樹、小嶋哲人
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 第VIII因子遺伝子のイントロン22逆位解析法-DNAポリメラーゼの比較-2008
- Author(s)
  藤森祐多、山田貴之、奥村薫、田中亮子、中島大輔、鈴木敦夫、宮脇由理、高木明、村手隆、小嶋哲人
- Organizer
  第9回日本検査血液学会学術集会
- Place of Presentation
  津
- Year and Date
  2008-07-26
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] Regulatory mechanism of neutral sphingomyelinase 2 gene expression by daJnorubicin in MCF-7 cells2008
- Author(s)
  H Ito, M Murakami, S Gao, A Furuhata, K Yoshida, Y Tagawa, S Sobue, A Takagi, T Kojima, M Suzuki, Y Banno, Y Nozawa, K Koizumi, T Murate
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] GATA-1, GATA-2 によるWT1発現調節の解析2008
- Author(s)
  古畑彩子、村上真史、高四強、木村有美、伊藤裕美、高木明、小嶋哲人、安部明弘、直江知樹、村手隆
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] ATRA inhibits ceramide kinase transcription through an ATRA-related transcription factor, COU~-TF1, in a human neuroblastoma cell line, SH-SY5Y cells2008
- Author(s)
  M Murakami, H Ito, S Gao, A Furuhata, K Yoshida, Y Tagawa, S Sobue, A Takagi, T Kojima, M Suzuki, Y Banno, Y Nozawa, T Murate
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] v-SrcによるSPHKl mRNA安定化と発現増強2008
- Author(s)
  祖父江沙矢加、村上真史、坂野喜子、伊藤裕美、高四強、古畑彩子、高木明、小嶋哲人、野澤義則、村手隆、市原正智
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 先天性凝固第VII 因子欠損症の分子病態解析2008
- Author(s)
  田中亮子、中島大輔、鈴木敦夫、宮脇由理、藤森祐多、山田貴之、奥村薫、勝見章、山本晃士、松下正、高松純樹、高木明、村手隆、小嶋哲人
- Organizer
  第31回日本血栓止血学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 日本人における血栓性素因遺伝子変異データベースの作成2008
- Author(s)
  藤森祐多、奥村薫、山田貴之、田中亮子、中島大輔、鈴木敦夫、宮脇由理、村手隆、高木明、小嶋哲人
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] Mutated Ras-induced. Phospholipase D1 transcripton in a human colon adenocarcinoma celt line, DLD-12008
- Author(s)
  S Gao, M Murakami, H Ito, A Furuhata, K Yoshida, Y Tagawa, S Sobue, A Takagi, T Kojima, Y Banno, M Suzuki, Y Nozawa, T Murate
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 女性血友病Aの分子病態解析2008
- Author(s)
  宮脇由理、鈴木敦夫、田中亮子、中島大輔、藤森祐多、山田貴之、奥村薫、高木明、村手隆、松下正、高松純樹、小嶋哲人
- Organizer
  第31回日本血栓止血学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 女性血友病Aの1例2008
- Author(s)
  宮脇由理、鈴木敦夫、田中亮子、中島大輔、藤森祐多、山田貴之、奥村薫、高木明、村手隆、松下正、高松純樹、小嶋哲人
- Organizer
  第9回愛知県医学検査学会
- Place of Presentation
  豊橋
- Year and Date
  2008-05-25
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 先天性プロテインC欠損症7家系における遺伝子解析2007
- Author(s)
  田中亮子、中島大輔、柏木隆宏、三田直美、藤森祐多、山田貴之、奥村薫、勝見章、松下正、山本晃士、高松純樹、高木明、村手隆、小嶋哲人
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  志摩
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 60歳時からの鼻出血で発症した遺伝性出血性末梢血管拡張症の遺伝子解析2007
- Author(s)
  中島大輔、田中亮子、柏木隆宏、三田直美、藤森祐多、山田貴之、奥村薫、寺西正明、高木明、村手隆、小嶋哲人
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  志摩
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] X染色体の不活性化を伴う女児血友病Bの分子病態解析2007
- Author(s)
  奥村薫、山田貴之、柏木隆宏、三田直美、藤森祐多、田中亮子、中島大輔、松下正、小関道夫、高木明、村手隆、小嶋哲人
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  志摩
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] Molecular basis of antithrombin deficiency in four Japanese patients with pregnancy-associated thrombosis : antithrombin gene abnormalities including two novel mutations2007
- Author(s)
  K. Okumura, Y. Fujimori, T. Kashiwagi, N. Sanda, T. Yamada, A. Takagi, T. Murate, T. Iwasaki, A. Katsumi, K. Yamamoto, T. Matsushita, T. Naoe, H. Saito, T. Kojima
- Organizer
  XXIInd Congress of ISTH, Geneva
- Place of Presentation
  Switzerland
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] JAK2V617F変異がもたらすBcl-XL発現増加とその転写調節機序の解明2007
- Author(s)
  木村有美、伊藤裕美、祖父江沙矢加、村上真史、根本聡、高四強、古畑彩子、高木明、小嶋哲人、幣光太郎、村手隆
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] The protein S thrombin sensitive region contributes regulation of warfarin treated des-γ-carboxylated protein S secretion: a study of a novel splice site mutation of protein S gene and its molecular consequences2007
- Author(s)
  H. Okada, S. Kunishima, M. Hamaguchi, A. Takagi, K. Yamamoto, J. Takamatsu, T. Matsushita, H. Saito, T. Kojima, T. Yamazak
- Organizer
  XXIInd Congress of ISTH
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2007-07-19
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] PROS1遺伝子プロモーテー領域内の一塩基置換による先天性プロテインS欠損症2007
- Author(s)
  三田直美、柏木隆宏、藤森祐多、田中亮子、中島大輔、山田貴之、奥村薫、高木明、村手隆、小嶋哲人
- Organizer
  第8回日本検査血液学会学術集会
- Place of Presentation
  福井
- Year and Date
  2007-07-22
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] アンチトロンビン欠損症と拡張型心筋症の合併家系における分子病態解析2007
- Author(s)
  藤森祐多、沖松秀美、柏木隆宏、三田直美、田中亮子、中島大輔、山田貴之、奥村薫、高木明、村手隆、内田文、野出孝一、小嶋哲人
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] Four novel causative mutations identified in the PROS1 gene of Japanese deep vein thrombosis patients with protein S deficiency2007
- Author(s)
  N. Sanda, Y. Fujimori, T. Kashiwagi, T. Yamada, K. Okumura, A. Takagi, T. Murate, T. Iwasaki, A. Katsumi, K. Yamamoto, T. Matsushita, T. Naoe, H. Saito, T. Kojima
- Organizer
  XXIInd Congress of ISTH
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 白血病細胞株におけるSPHK1発現と抗癌剤Daunorubicin体制との関連2007
- Author(s)
  祖父江沙矢加、村上真史、根本聡、伊藤裕美、木村有美、高四強、古畑彩子、高木明、小嶋哲人、村手隆
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] Precise genetic abnormalities in four hemophilia B patients with large deletions of X-chromosome including entire F8
- Author(s)
  Yuki Nakamura, Moe Murata, Yuki Takagi, Toshihiro Kozuka, Yukiko Nakata, Ryo Hasebe, Akira Takagi, Tadashi Matsushita, Tetsuhito Kojima
- Organizer
  The 8th Congress of Asia Pacific Society of Thrombosis and Hemostasis
- Place of Presentation
  Hanoi
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] Optimization of the antithrombin resistance assay for the automated analyzer
- Author(s)
  Moe Murata, Yuki Takagi, Yuki Nakamura, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Tetsuhito Kojima
- Organizer
  The 8th Congress of Asia Pacific Society of Thrombosis and Hemostasis
- Place of Presentation
  Hanoi
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] アンチトロンビン抵抗性検出検査法の自動凝固検査機器への最適化
- Author(s)
  村田　萌、高木夕希、中村友紀、長谷部　瞭、小塚敏弘、中田　悠紀子、高木　明、村手　隆、松下　正、小嶋哲人
- Organizer
  第15回日本検査血液検査血液学会学術集会
- Place of Presentation
  仙台
- Year and Date
  2014-07-20 – 2014-07-21
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] Optimization of the antithrombin resistance assay for the automated analyzer
- Author(s)
  Moe Murata, Yuki Takagi, Yuki Nakamura, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Tetsuhito Kojima
- Organizer
  The 8th Congress of Asia Pacific Society of Thrombosis and Hemostasis (APSTH)
- Place of Presentation
  Hanoi, Vietnam
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] Precise genetic abnormalities in four hemophilia B patients with large deletions of X-chromosome including entire F9
- Author(s)
  Yuki Nakamura, Moe Murata, Yuki Takagi, Toshihiro Kozuka, Yukiko Nakata, Ryo Hasebe, Akira Takagi, Tadashi Matsushita, Tetsuhito Kojima
- Organizer
  The 8th Congress of Asia Pacific Society of Thrombosis and Hemostasis (APSTH)
- Place of Presentation
  Hanoi, Vietnam
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] アンチトロンビン抵抗性検出検査法の自動凝固検査機器への最適化
- Author(s)
  村田　萌、高木夕希、中村友紀、長谷部　瞭、小塚敏弘、中田　悠紀子、高木　明、村手　隆、松下　正、小嶋哲人
- Organizer
  第15回日本検査血液検査血液学会学術集会
- Place of Presentation
  仙台国際センター
- Year and Date
  2014-07-20 – 2014-07-21
- Data Source
  KAKENHI-PROJECT-25293129

1. KOJIMA Tetsuhito (40161913)

# of Collaborated Projects: 15 results

# of Collaborated Products: 148 results
2. MURATE Takashi (30239537)

# of Collaborated Projects: 7 results

# of Collaborated Products: 5 results
3. MATSUSHITA Tadashi (30314008)

# of Collaborated Projects: 6 results

# of Collaborated Products: 52 results
4. SUZUKI Motoshi (80236017)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
5. BANNO Yoshiko (50116852)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
6. YAKMAMOTO Koji (90362251)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
7. NOZAWA Yoshinori (10021362)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. KINOSHITA Tomohiro (60283446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KOIZUMI Keiko (00118027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OKADA Tamotsu (00023771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OHTA Tatsuro (00109323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 内田俊樹

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 大橋春彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. IWAKI Soichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. KATSUMI Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 田村彰吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 藤井聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 野沢義則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 中村光浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 國島伸治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKAGI Akira 高木 明

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Development of a new detection method in antithrombin resistance to avoid the effect of antithrombotic drug treatmentPrincipal Investigator

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Development of new examination methods for thrombotic tendency with TM resistance and FXa AT resistancePrincipal Investigator

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Development of new analytical method for antithrombin resistancePrincipal Investigator

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TAKAGI Akira 高木明

[Journal Article] アンチトロンビン抵抗性の診断　-検査法を中心に-2018