KOJIMA Tetsuhito 小嶋哲人

Researcher Number	40161913
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2016 – 2019: 名古屋大学, 医学系研究科(保健), 教授 2017: 名古屋大学, 医学(系)研究科, 教授 2015: 名古屋大学, 医学部, 教授 2015: 名古屋大学, 大学院医学系研究科, 教授 2012 – 2015: 名古屋大学, 医学(系)研究科(研究院), 教授 … More 2013: 名古屋大学, 大学院医学系研究科, 教授 2012: 名古屋大学, 医学系研究科(保健), 教授 2000 – 2011: School of Medicine, Nagoya University, Professor, 医学部, 教授 2008: Nagoya University, 医学部・保健学科, 教授 1999: Nagoya University, School of Medicine, Associate Professor, 医学部, 助教授 1994 – 1998: Nagoya University School of Medicine, Assistant Professor, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Hematology / Laboratory medicine / Hematology / 血管生物学 Except Principal Investigator Laboratory medicine / Hematology / Hematology / Medium-sized Section 90:Biomedical engineering and related fields / General internal medicine(including psychosomatic medicine) / Laboratory medicine
Keywords	Principal Investigator ヘパラン硫酸プロテオグリカン / Ryudocan / fibronectin / focal adhesion / bFGF / マウス / 欠失マウス / ryudocan / 組織修復 / Tissue Factor Pathway Inhibitor(TFPI) … More / 血管内皮細胞 / May-Hegglin anomaly / MYH9 / NMMHCA / PAI-1 / hypoxia / ryudocan (syndecan-4) / heparan sulfate proteoglycan / アンチトロンビン・レジスタンス（ATR） / トロンビン / 心筋梗塞 / ノックアウトマウス / midkine(MK) / 内科 / 人工授精 / アンチトロンビン・レシスタンス（ATR） / R593Lノックインマウス / ジーンタ一ゲティング / アンチトロンビン / Arg593Leuノックインマウス / Na+結合領域 / ATR残存凝固活性 / 自動化機器 / ATR検出・臨床検査法 / 遺伝子異常 / プロトロンビン / Knock in mouse / Alport symptom / Knock out mouse / immunostaining / macrothrombocytopenia / 巨大血小板 / Cre-recombinase / ノックイン / ノックインマウス / Alport徴候 / 免疫染色解析 / May-Hegglin異常症 / 巨大血小板性血小板減少症 / obese / aged, older / TF / restraint stress / thrombotic diseases / stress / competitive RT-PCR法 / 血栓傾向 / in situ hybridization法 / 加齢 / 抗TNF-α抗体 / 老齢 / TF(組織因子)発現 / 肥満 / 加齢(老齢) / TF(組織因子) / 拘束ストレス負荷 / 血栓性疾患 / ストレス / obstructive nephropathy / K-carrageenan / renal damage / deficient mice / heparan sulfate proteoglvcan / 細胞接着 / カッパーカラゲナン / 閉塞性腎症 / カッパーカラゲナ / 腎臓機能障害 / Tissue-repairing / maintain fluidity / follicular fluid / guranulosa cells / mouse / 抗凝固活性 / Lusiferase reporter assay / VEGF / Ryudocan(Syndecan-4) / ヘパラン硝酸プリテオグリカン / 低酸素 / 流動性維持 / 卵胞液 / 卵巣顆粒膜細胞 / ryudocan(syndecan-4) / null mice / Heparan sulfate proteoglycan / 血中濃度 / promoter activity / ryudocan gene / ryudocan cDNA / mouse ryudocan / TFPI / midkine / Immuno-histochemistry / Proteoglycan / Heparan Sulfate / Inhibition radioimmuno-assay / ミッドカイン(MK) / Tisssue Factor Pathway Inhibitor (TFPI) / ミドカイン(MK) / 免疫組織染色 / 特異抗体 / 血管内皮 / トロンボモジュリン／プロテインC経路 / R593Lプロトロンビン-マウス / ﾄﾛﾝﾎﾞﾓｼﾞｭﾘﾝ/ﾌﾟﾛﾃｲﾝC経路 / R593Lﾌﾟﾛﾄﾛﾝﾋﾞﾝ-ﾏｳｽ / ｱﾝﾁﾄﾛﾝﾋﾞﾝ・ﾚｼﾞｽﾀﾝｽ(ATR) / 相同組換え / R593Lプロトロンビン-ノックインマウス / トロンボモジュリン / 一塩基置換 / 遺伝性血栓症 / プロトロンビン異常症 / アンチトロンビン-レジスタンス（ATR） / スクリーニング検査法 / プロテインS欠損症 / プロテインC欠損症 / アンチトロンビン欠損症 / ｽｸﾘ―ﾆﾝｸﾞ検査法 / ｱﾝﾁﾄﾛﾝﾋﾞﾝ抵抗性 / ﾌﾟﾛﾃｲﾝS欠損症 / ﾌﾟﾛﾃｲﾝC欠損症 / ｱﾝﾁﾄﾛﾝﾋﾞﾝ欠損症 / 原因遺伝子変異 / アンチトロンビン抵抗性 / 遺伝子変異 / 先天性血栓性素因 / 静脈血栓塞栓症 / 臨床血液学 / PS mRNA / エストラディオール(E2) / HepG2細胞 / ルシフェラーゼ・レポーター解析 / プロモーター / 遺伝子欠失 / PROS1遺伝子 / プロテインS(PS)欠損症 … More Except Principal Investigator 血栓症 / sphingosine kinase 1 / Thrombosis / promoter analysis / ストレス / gene expression / 線溶 / サイトカイン / 脂肪細胞 / thrombosis / platelet / プロテインS / Ryudocan / 病態解析 / Sp1 protein / 転写調節 / 遺伝子発現 / MEN2 type tumor / GDNF / sphingolipid metabolites / acute leukemia / quantitative RT-PCR / Adipocyte / Cytokine / Stress / Fibrinolysis / Trk A receptor / nerve growth factor / NMMHCA / May-Hegglin anomaly / LPS / Knock owt / recombination / Sindecan / Antithrombin / 血小板 / Polymerase chain reaction / von Willebrand factor / IL-1 / TFPI / impaired secretion / protein C deficiency / Thrombophilia / プロテインC / 分泌異常 / 血栓性素因 / 血管内皮 / cDNA / 血液流動性 / 静脈血栓塞栓症 / 敗血症 / 老化 / プロモーター解析 / 国際情報交換 / アンチトロンビン抵抗性 / 糖尿病 / 肥満 / ATRA / スフィンゴシンキナーゼ1 / 骨髄微小環境 / iPS細胞 / 造血微小環境 / 巨核球 / 中国 / 英国 / シンガポール / ハンガリー / 韓国 / 栄養学 / 内科 / 遺伝学 / 予防治療戦略 / protein C / protein S / 予防治療戦 / 発症要因 / 国際学術調査 / アジア人 / 遺伝性血栓性素因 / プロトロンビンアクチベータ / 変異型プロトロンビン / アンチトロンビン抵抗性検出法 / アンチトロンビン / 凝固第X因子 / 抗血栓薬 / Lone flight thrombosis / Gene expression / Fibrin / エコノミー症候群 / ロングフライト症候群 / フィブリン / Elecrophysiology / myelodysplastic syndrome / RET signal / myelodysplastic syndromes / MEN2 type promoter / anti-cancer drug sensitivity / myelodysplastic sundrome / sphinosine kinase1 / Atherosclerosis / Diabetes / Obesity / 動脈硬化 / all trans retinoic acid / neuronal apoptosis / SPHK1 gene expression / anti human SPHK1 antibody / Spl protein / Congenital thrombocytopenia / Congenital platelet disorders / MYH9 disorders / 血小板減少症 / 血小板機能異常症 / 先天性血小板減少症 / 先天性血小板異常症 / MYH9異常症 / polyclonal antibody / スフィンゴシンキナーゼ / プロモータ解析 / MEG-O1 / ポリクローナル抗体 / Knock out mouse / Svndecan / antithrombin / alanine scanning mutagencsis / coronary heartdisease / polymerase chain reaction / GPIh / mutant / botrocetin / ristocetin / von Willebrand因子 / alanine scanning mutagenesis / coronay heart disease / Polvmerase chain reaction / GPIb / Fibrin deposition / Gene Expression / TNF-alpha / Sepsis / 線溶能 / 血液凝固 / フイブリン沈着 / 遺伝子発現量 / TNF-α / molecular model / conformational change / expression / carboxyl-terminaldeletion / gene mutation / 遺伝子治療 / AAV / alternative splicing / exon skipping / 血小板mRNA / nonsense mutation / プロテインS欠乏症 / 分子モデル / 立体構造変化 / 発現実験 / COOH末梢除変異体 / 遺伝子異常 / プロテインC欠乏症 / promoter activity / ryudocan gene / heparan sulfate proteoglycan / endothelium / protein S deficiency / 生理的凝固阻止因子 / プロモーター活性 / Ryudocan遺伝子 / ヘパラン硫酸プロテオグリカン / protein S欠損症 / Immuno-histochemistry / Proteoglycan / Heparan Sulfate / Endothelial cell / ヒト染色体20q12 / alternative polyadenylation / Inhibition radioimmuno assay / 特異抗体 / 免疫組織染色 / ヘパラン硫酸 / transcription / CREB / serum-depleted condition / hypoxia / USP2 / アンドロジェン / 前立腺癌細胞株 / ACDase / 血清除去 / SPHK2 / 代謝酵素遺伝子発現調節 / スフィンゴ脂質代謝 / 悪性腫瘍細胞株 / 白血病細胞株 / 酸性スフィンゴミエリナーゼ / レスベラトロール / Anti-cancer action / Phytochemical / Food ingredient / Stress response / Cancer cell / Sphingolipid metabolism / 血栓傾向 / トロンボモジュリン抵抗性 / プロトロンビン分子異常 / 危険因子 / 病態検査学 / 神経細胞 / 交感神経 / 腎糸球体 / 菌体毒素 / 血栓 / 心筋細胞 / 血管内皮細胞 / 突然死 / PAI-1 / 炎症 / PKC delta / Sp1転写因子 / MCF-7細胞株 / NSmase2 / ERK pathway / S1P receptor 2 / CD44 / human colon cancer cell / chemical differentiation / c-Myb / Friend cell / SPHK1 / human cancer cell lines / anti-cancer drug / metabolic enzyme / sphingolipid / 遺伝子変異 / プロトロンビン / 検査法開発 / 血栓症リスク / 制御因子抵抗性 / 変異プロトロンビン / プロトロンビン変異 / 臨床血液学 / 高血圧 / PKC alpha / タンパク質リン酸化 / HuR / AUF1 / 3'-UTR / v-SRCガン遺伝子 / mRNA寿命の延長 / ダウノルビシン / 転写抑制機序 / 転写因子およびプロモーター領域結合部位 / 脂肪分化ならびに癌化 / PLD1 transcription / GATA-4 protein / DNA pulldown assay and chromatin immunoprecipitation assay / cellular S1P level / real time RT-PCT / human lung cancer cell lines / sphingosine 1-phosphate lyase / ホスホリパーゼD1,ホスホリパーゼD2 / スフィンゴシン1リン酸リアーゼ / 中性スフィンゴミエリナーゼ2 / セラミドキナーゼ / スフィンゴシンキナーゼ2 / スフィンゴシン1リン酸 / セラミド / 凝固線溶 / 組織因子 / Plasminogen activator inhibitor-1 Less

Development zeno-free/self-feeder culture system for an efficient iPSC derived platelet production
- Principal Investigator
  
  Tamura Shogo
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Nagoya University
Development of a new detection method in antithrombin resistance to avoid the effect of antithrombotic drug treatment
- Principal Investigator
  
  TAKAGI AKIRA
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Novel mutation search of antithrombin resistance and its pathological analysis research by mouse modelPrincipal Investigator
- Principal Investigator
  
  Kojima Tetsuhito
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Stress response of cancer cells focusing the sphingolipid metabolism and its modulation by food ingredients
- Principal Investigator
  
  MURATE Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Chubu University
  Nagoya University
Investigation into thrombophilia indigenous to Asian populations and establishment of new strategy for preventing thrombosis
- Principal Investigator
  
  TSUDA Hiroko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Nakamura Gakuen College
Molecular elucidation of antithrombin resistance mechanism and development of thrombophilia model mouse.Principal Investigator
- Principal Investigator
  
  Kojima Tetsuhito
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Development of new examination methods for thrombotic tendency with TM resistance and FXa AT resistance
- Principal Investigator
  
  TAKAGI AKIRA
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Elucidation of mechanisms under prothrombotic state with aging
- Principal Investigator
  
  Yamamoto Koji
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Saitama Medical University
  Nagoya University
The involvement of sphingolipid metabolism in anti cancer drug sensitivity of malignant cells
- Principal Investigator
  
  MURATE Takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Gene analysis of a novel thrombotic risk factor; antithrombin-resistance.Principal Investigator
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Development of new analytical method for antithrombin resistance
- Principal Investigator
  
  TAKAGI Akira
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Involvement and abnormality of lysosphingolipid metabolic enzymes in malignant diseases
- Principal Investigator
  
  MURATE Takashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Elucidation of molecular pathogenesis and control of thrombosis in metabolic syndrome
- Principal Investigator
  
  YAMAMOTO Koji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Elucidation of Molecular basis of inherited and acquired protein S deficiency as a thrombosis risk factorPrincipal Investigator
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Aberrant expression of sphingosine kinase and its pathological significance of malignant tumors and neuronal degenerative diseases
- Principal Investigator
  
  MURATE Takashi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Analysis and regulation of aberrant expression of sties-responsive prothrombotic genes in a model of myocardial and cerebral infarction
- Principal Investigator
  
  YAMAMOTO Koji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Molecular mechanisms of thrombosis in mouse model induced by age and stressPrincipal Investigator
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Elucidation of molecular basis of May-Hegglin anomaly and its related disordes
- Principal Investigator
  
  SAITO Hidehiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  National Hospital Organization Nagoya Medical Center, Clinical Research Center
Basic analysis of sphingolipid metabolising enzyme and its application to the diagnosis of hematological and neuronal diseases
- Principal Investigator
  
  TAKASHI Murate
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Analysis on thrombotic tendency in obesity and diabetes by use of model mouse
- Principal Investigator
  
  YAMAMOTO Koji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Molecular mechanisms of thrombosis in mouse model induced by age and stressPrincipal Investigator
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
The significance of serum sphingosine 1-phospahte in hematological diseases and the regulatory mechanism of sphingosine kinase
- Principal Investigator
  
  MURATE Takeshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagoya University
Antithrombin deficiency in mice results in embryonic lethality and thrombotic tendency.
- Principal Investigator
  
  TAKAMATU Junki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
ストレス負荷により血栓形成傾向が促進されるか?(ストレス負荷マウスでは血液凝固線溶因子の組織内発現異常が認められるか?)
- Principal Investigator
  
  SAITO Hidehiko
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Research on biological function of ryudocan by knockout mice analysis.Principal Investigator
- Principal Investigator
  
  KOJIMA Tetsuhiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Identification of the regulatory elements of human von Willebrand factor for binding to platelet GPlb.
- Principal Investigator
  
  MATSUSHITA Tadashi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Down-regulation of murine tissue factor pathway inhibitor mRNA by endotoxin and tumor neerosis factor-alpha In vitro and In vivo.
- Principal Investigator
  
  SAITO Hidehiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
動脈硬化の発症病態に関わるHSPG・Ryudocanの機能解析Principal Investigator
- Principal Investigator
  
  小嶋哲人
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nagoya University
Establishment of Ryudocan Null Mouse and ELISA for Blood Levels of RyudocanPrincipal Investigator
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Ryudocan expression and its regulationPrincipal Investigator
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
血管新生・動脈硬化症に関わる血管内皮HSPG・Ryudocanの機能解析Principal Investigator
- Principal Investigator
  
  小嶋哲人
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
Molecular Biological Analysis for Mechanism of Thombosis Regulation and Its Aplication for Clinical Desease.
- Principal Investigator
  
  SAITO Hidehiko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Molecular and Functional Analysis of Heparan sulfate Proteoglycan-Ryudocan.Principal Investigator
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Molecular Biological Analysis for Mechanism of Thombosis Regulation and Its APlication for Clinical Desease.
- Principal Investigator
  
  SAITO Hidehiko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Molecular-patholical Analysis for the Biolocical Role of Ryudocan (Endothilal Heparan Sulfate Proteoglycan) on Vasculat Damage.Principal Investigator
- Principal Investigator
  
  KOJIMA Tetsuhito
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  血管生物学
- Research Institution
  Nagoya University
Molecular and Pathological Analysis of Anticoagulant Heparan Sulfate Proteoglycan from Endothelial Cell
- Principal Investigator
  
  SAITO Hidehiko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University

[Book] 血液疾患　最新の治療　2017-20192017
- Author(s)
  兼松毅、小嶋哲人
- Total Pages
  372
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-16K09825
[Book] みんなに役立つ血友病の基礎と臨床　改訂3版2016
- Author(s)
  田村彰吾、小嶋哲人
- Total Pages
  463
- Publisher
  医歯ジャーナル社
- Data Source
  KAKENHI-PROJECT-16K09825
[Book] Annual Review 2016血液2015
- Author(s)
  高木夕希、小嶋哲人
- Total Pages
  234
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25293129
[Book] 臨床検査法提要（改訂第34版）2015
- Author(s)
  小嶋哲人、高木明
- Total Pages
  1970
- Publisher
  金原出版株式会社
- Data Source
  KAKENHI-PROJECT-25293129
[Book] 臨床検査法提要（改訂第34版）2015
- Author(s)
  小嶋哲人、高木明
- Total Pages
  21
- Publisher
  金原出版株式会社
- Data Source
  KAKENHI-PROJECT-25460683
[Book] 血液疾患診療ハンドブック・改訂3版2015
- Author(s)
  鈴木伸明、小嶋哲人
- Total Pages
  591
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-25293129
[Book] 新・血栓止血血管学　凝固と炎症2015
- Author(s)
  小嶋哲人
- Total Pages
  189
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-25293129
[Book] 新・血栓止血血管学　抗凝固と線溶2015
- Author(s)
  小嶋哲人
- Total Pages
  133
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-25293129
[Book] ファーマナビゲーター抗凝固療法編2015
- Author(s)
  高木夕希、小嶋哲人
- Total Pages
  415
- Publisher
  株式会社メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-25293129
[Book] 「EBM血液疾患の治療　2015-2016」2014
- Author(s)
  村田萌、小嶋哲人
- Total Pages
  555
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25293129
[Book] 徹底ガイド　DICのすべて2014-152014
- Author(s)
  小嶋哲人
- Total Pages
  392
- Publisher
  総合医学社
- Data Source
  KAKENHI-PROJECT-25293129
[Book] 改訂第8版　内科学書　Vol.６　血液・造血器疾患、神経疾患（分担）2013
- Author(s)
  小嶋哲人
- Total Pages
  493
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-25293129
[Book] 「みんなに役立つ血友病の基礎と臨床　改訂版」2012
- Author(s)
  村田萌、小嶋哲人
- Total Pages
  423
- Publisher
  医歯ジャーナル社
- Data Source
  KAKENHI-PROJECT-22590524
[Book] フォンダパリヌクスの基礎循環器内科医のためのXa阻害薬のすべて2012
- Author(s)
  小嶋哲人
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-22590524
[Book] 「あなたも名医！新しい経口抗凝固薬、どう使う」2012
- Author(s)
  小嶋哲人
- Total Pages
  162
- Publisher
  日本医事新報社
- Data Source
  KAKENHI-PROJECT-22590524
[Book] あなたも名医!新しい経口抗凝固薬、どう使う2012
- Author(s)
  小嶋哲人
- Publisher
  日本医事新報社
- Data Source
  KAKENHI-PROJECT-22590524
[Book] わかりやすい血栓と止血の臨床2011
- Author(s)
  小嶋哲人
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-22590524
[Book] 先天性凝固阻止因子欠乏症(AT,PC,PS欠損症)わかりやすい血栓と止血の臨床2011
- Author(s)
  小嶋哲人
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-22590524
[Book] 抗血栓薬の最前線 -基礎と臨床2011
- Author(s)
  小嶋哲人
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-22590524
[Book] 血液疾患最新の治療 2011-20132010
- Author(s)
  小嶋哲人
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-22590524
[Book] 血液疾患最新の治療2011-20132010
- Author(s)
  小嶋哲人
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-22590524
[Book] I.基礎 3.血友病の病態 3)血友病Bの分子病態血友病の基礎と臨床(白幡聡編)2009
- Author(s)
  奥村薫、小嶋哲人
- Publisher
  医歯ジャーナル社
- Data Source
  KAKENHI-PROJECT-19590553
[Book] In講義録血液・造血器疾患(小澤敬也/直江知樹/坂田洋一編)I.血液・造血器を深く知るための基本講義B.止血・凝固システムを学ぶ凝固系制御機構2008
- Author(s)
  小嶋哲人
- Publisher
  株式会社メディカルビュー社
- Data Source
  KAKENHI-PROJECT-19590553
[Book] In抗凝固薬の適正な使い方(第2版)櫻川信男/上塚芳郎/和田秀夫編Chapter4. その他の抗凝固薬Paragraph1.ヘパリン、低分子量ヘパリン2008
- Author(s)
  小嶋哲人
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-19590553
[Book] 講義録血液・造血器疾患学2008
- Author(s)
  小嶋哲人
- Total Pages
  301
- Publisher
  株式会社メデイカルビュー社
- Data Source
  KAKENHI-PROJECT-19590553
[Book] Hypercoagulable States. K. Tanaka, and E.W. Davie, eds; Recent Advances in Thrombosis and Hemostasis2008
- Author(s)
  T Kojima and H Saito
- Publisher
  Springer(printed in Japan)
- Data Source
  KAKENHI-PROJECT-19590553
[Book] 抗凝固薬の適正な使い方(第2版)2008
- Author(s)
  小嶋哲人
- Total Pages
  430
- Publisher
  医書薬出版株式会社
- Data Source
  KAKENHI-PROJECT-19590553
[Book] Part 4. Xa阻害薬の薬理的特徴をみる1. 抗凝固薬の歴史とXa阻害薬の開発目的を探るXa阻害薬のすべて(池田康夫/坂田洋一/丸山征郎(編))2007
- Author(s)
  小嶋哲人
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-19590553
[Book] 先天性血栓性疾患の治療法v.凝固・血小板「EBM血液疾患の治療2008-2009」(押味和夫/別所正美/岡本真一郎/加藤淳(編))2007
- Author(s)
  岩崎年宏, 小嶋哲人
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19590553
[Book] 先天性アンチトロンビン欠損症C.血小板・凝固線溶「専門医のための薬物療法Q&A : 血液」(押味和夫/長澤俊郎/小松則夫(編))2007
- Author(s)
  小嶋哲人
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19590553
[Book] Xa阻害薬のすべて(抗凝固薬の歴史とXa阻害薬の開発目的を探る)2007
- Author(s)
  小嶋哲人(池田康夫)
- Total Pages
  233
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-19590553
[Book] 三輪・血液病学2006
- Author(s)
  小嶋哲人, (浅野茂隆ら監修)
- Total Pages
  2070
- Publisher
  文光堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590490
[Book] 三輪・血液病学2006
- Author(s)
  小嶋哲人(浅野茂隆ら監修)
- Total Pages
  2070
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-17590490
[Book] MIWA HEMATOLOGY2006
- Author(s)
  T.Kojima, (ed.by S.Asano, et al.)
- Total Pages
  2070
- Publisher
  Bunko-do
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590490
[Book] 血液の事典2004
- Author(s)
  小嶋哲人(平井久丸ら編)
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-15591000
[Book] 医学大事典2003
- Author(s)
  小嶋哲人(伊藤正男ら編)
- Publisher
  医学書院
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591000
[Book] Igaku Shoin's Medical Dictionary2003
- Author(s)
  T.Kojima(ed.by M.Ito, et al.)
- Total Pages
  30
- Publisher
  Igaku Shoin
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591000
[Journal Article] Higher FVIII:C Measured by Chromogenic Substrate Assay Than by One-Stage Assay Is Associated With Silent Hemophilic Arthropathy2020
- Author(s)
  Mika Ogawa, Nobuaki Suzuki, Nobunori Takahashi, Shogo Tamura, Atsuo Suzuki, Sachiko Suzuki, Yuua Hattori, Misaki Kakihara, Takeshi Kanematsu, Toshihisa Kojima, Akira Katsumi, Fumihiko Hayakawa, Tetsuhito Kojima, Naoki Ishiguro , Hitoshi Kiyoi , Tadashi Matsushita
- Journal Title
  
  Thromb Res
  
  Volume: 188 Pages: 103-105
- DOI
  10.1016/j.thromres.2020.01.003
- NAID
  120006872431
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08853, KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-17K09902, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K19910, KAKENHI-PROJECT-20K08711, KAKENHI-PROJECT-18H02835
[Journal Article] Apparent Synonymous Mutation F9 c.87A>G Causes Secretion Failure by In-Frame Mutation With Aberrant Splicing2019
- Author(s)
  Odaira K, Tamura S, Suzuki N, Kakihara M, Hattori Y, Tokoro M, Suzuki S, Takagi A, Katsumi A, Hayakawa F, Okamoto S, Suzuki A, Kanematsu T, Matsushita T, Kojima T.
- Journal Title
  
  Thromb Res
  
  Volume: 179 Pages: 95-103
- DOI
  10.1016/j.thromres.2019.04.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08853, KAKENHI-PROJECT-18H02835, KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-17K09902, KAKENHI-PROJECT-18K19910
[Journal Article] Successful Perioperative Combination of High-Dose FVIII Therapy Followed by Emicizumab in a Patient with Hemophilia A with Inhibitors2019
- Author(s)
  Okamoto Shuichi、Suzuki Nobuaki、Suzuki Atsuo、Suzuki Sachiko、Tamura Shogo、Suzuki Mochihito、Takahashi Nobunori、Kojima Toshihisa、Kanematsu Takeshi、Kojima Tetsuhito、Kiyoi Hitoshi、Ishiguro Naoki、Matsushita Tadashi
- Journal Title
  
  TH Open
  
  Volume: 03 Issue: 04 Pages: e364-e366
- DOI
  10.1055/s-0039-3401001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-17K09902, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K19910
[Journal Article] Molecular basis of SERPINC1 mutations in Japanese patients with antithrombin deficiency2019
- Author(s)
  Tamura Shogo、Hashimoto Erika、Suzuki Nobuaki、Kakihara Misaki、Odaira Koya、Hattori Yuna、Tokoro Mahiru、Suzuki Sachiko、Takagi Akira、Katsumi Akira、Hayakawa Fumihiko、Suzuki Atsuo、Okamoto Shuichi、Kanematsu Takeshi、Matsushita Tadashi、Kojima Tetsuhito
- Journal Title
  
  Thrombosis Research
  
  Volume: 178 Pages: 159-170
- DOI
  10.1016/j.thromres.2019.04.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09451, KAKENHI-PROJECT-19K08853, KAKENHI-PROJECT-18H02835, KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-17K09902, KAKENHI-PROJECT-18K19910
[Journal Article] Apparent synonymous mutation F9 c.87A>G causes secretion failure by in-frame mutation with aberrant splicing.2019
- Author(s)
  Odaira K, Tamura S, Suzuki N, Kakihara M, Hattori Y, Tokoro M, Suzuki S, Takagi A, Katsumi A, Hayakawa F, Okamoto S, Suzuki A, Kanematsu T, Matsushita T, Kojima T
- Journal Title
  
  Thrombosis Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09825
[Journal Article] Molecular basis of SERPINC1 mutations in Japanese patients with antithrombin deficiency.2019
- Author(s)
  Tamura S, Hashimoto E, Suzuki N, Kakihara M, Odaira K, Hattori Y, Tokoro M, Suzuki S, Takagi A, Katsumi A, Hayakawa F, Suzuki A, Okamoto S, Kanematsu T, Matsushita T, Kojima T
- Journal Title
  
  Thrombosis Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09825
[Journal Article] Familial pulmonary thromboembolism with a prothrombin mutation and antithrombin resistance.2018
- Author(s)
  10)Yoshida R, Seki S, Hasegawa J, Koyama T, Yamazaki K, Takagi A, Kojima T, Yoshimura M
- Journal Title
  
  J Cardiol Cases.
  
  Volume: in press Issue: 6 Pages: 197-199
- DOI
  10.1016/j.jccase.2018.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09825, KAKENHI-PROJECT-16K08967
[Journal Article] Optimisation of antithrombin resistance assay as a practical clinical laboratory test: Development of prothrombin activator using factors Xa/Va and automation of assay2018
- Author(s)
  Tamura S.、Suga Y.、Tanamura M.、Murata-Kawakami M.、Takagi Y.、Hottori Y.、Kakihara M.、Suzuki S.、Takagi A.、Kojima T.
- Journal Title
  
  International Journal of Laboratory Hematology
  
  Volume: 40 Issue: 3 Pages: 312-319
- DOI
  10.1111/ijlh.12786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19910, KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-16K08967, KAKENHI-PROJECT-16K09825
[Journal Article] Vwf K1362A resulted in failure of protein synthesis in mice．2018
- Author(s)
  Sanda N, Suzuki N, Suzuki A, Kanematsu T, Kishimoto M, Hasuwa H, Takagi A, Kojima T, Matsushita T, Nakamura S
- Journal Title
  
  Int J Hematol.
  
  Volume: in press Issue: 4 Pages: 428-435
- DOI
  10.1007/s12185-017-2394-y
- NAID
  120006501193
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09825, KAKENHI-PROJECT-17K09902
[Journal Article] Combined deficiency of factors V and VIII by chance coinheritance of parahaemophilia and haemophilia A, but not by mutations of either LMAN1 or MCFD2, in a Japanese family.2018
- Author(s)
  Suzuki S, Nakamura Y, Suzuki N, Yamazaki T, Takagi Y, Tamura S, Takagi A, Kanematsu T, Matsushita T, Kojima T
- Journal Title
  
  Haemophilia.
  
  Volume: 24 Issue: 1
- DOI
  10.1111/hae.13360
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09825, KAKENHI-PROJECT-17H05073
[Journal Article] アンチトロンビン抵抗性の診断　-検査法を中心に-2018
- Author(s)
  高木明、田村彰吾、小嶋哲人
- Journal Title
  
  日本検査血液学会誌
  
  Volume: 19 Pages: 393-400
- Data Source
  KAKENHI-PROJECT-16K08967
[Journal Article] In vitro exploration of latent prothrombin mutants conveying antithrombin resistance.2017
- Author(s)
  Tamura S, Murata-Kawakami M, Takagi Y, Suzuki S, Katsumi A, Takagi A, Kojima T.
- Journal Title
  
  Thromb Res.
  
  Volume: 159 Pages: 33-38
- DOI
  10.1016/j.thromres.2017.09.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09451, KAKENHI-PROJECT-16K08967, KAKENHI-PROJECT-16K09825, KAKENHI-PROJECT-17H05073
[Journal Article] Clinical and biochemical characterization of the prothrombin Belgrade mutation in a large Serbian pedigree: new insights into the antithrombin resistance mechanism.2017
- Author(s)
  Miljic P, Gvozdenov M, Takagi Y, Takagi A, Pruner I, Dragojevic M, Tomic B, Bodrozic J, Kojima T, Radojkovic D, Djordjevic V.
- Journal Title
  
  J Thromb Haemost.
  
  Volume: 15 Issue: 4 Pages: 670-677
- DOI
  10.1111/jth.13618
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08967, KAKENHI-PROJECT-16K09825
[Journal Article] First case report of hemophilia B Leyden in Japan.2017
- Author(s)
  Yamashita A, Nagae C, Mori M, Ashikaga T, Kojima T, Taki M
- Journal Title
  
  Int J Hematol.
  
  Volume: 106 Issue: 1 Pages: 135-137
- DOI
  10.1007/s12185-017-2194-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09825
[Journal Article] The first case of antithrombin-resistant prothrombin Belgrade mutation in Japanese.2016
- Author(s)
  Kishimoto M, Suzuki N, Murata M, Ogawa M, Kanematsu T, Takagi A, Kiyoi H, Kojima T, Matsushita T
- Journal Title
  
  Ann Hematol.
  
  Volume: 95 Issue: 3 Pages: 541-542
- DOI
  10.1007/s00277-015-2533-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293129
[Journal Article] 新たな血栓性素因：アンチトロンビンレジスタンス2016
- Author(s)
  小嶋哲人、高木明、村田萌、高木夕希
- Journal Title
  
  日本産婦人科・新生児血液学会誌
  
  Volume: 25 Pages: 66-72
- Data Source
  KAKENHI-PROJECT-25460683
[Journal Article] Distinct X chromosomal rearrangements in four haemophilia B patients with entire F9 deletion.2016
- Author(s)
  Nakamura Y, Ando Y, Takagi Y, Murata M, Kozuka T, Nakata Y, Hasebe R, Takagi A, Matsushita T, Shima M, Kojima T.
- Journal Title
  
  Haemophilia.
  
  Volume: 22 Issue: 3 Pages: 433-439
- DOI
  10.1111/hae.12849
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09825
[Journal Article] The first case of antithrombin-resistant prothrombin Belgrade mutation in Japanese2016
- Author(s)
  Kishimoto M, Suzuki N, Murata M, Ogawa M, Kanematsu T, Takagi A, Kiyoi H, Kojima T, Matsushita T
- Journal Title
  
  Ann Hematol.
  
  Volume: 95 Pages: 541-542
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460683
[Journal Article] Syndecan 4 Mediates Nrf2-dependent Expansion of Bronchiolar Progenitors That Protect Against Lung Inflammation.2016
- Author(s)
  Santoso A, Kikuchi T, Tode N, Hirano T, Komatsu R, Damayanti T, Motohashi H, Yamamoto M, Kojima T, Uede T, Nukiwa T, Ichinose M.
- Journal Title
  
  Mol Ther.
  
  Volume: 24 Issue: 1 Pages: 41-52
- DOI
  10.1038/mt.2015.153
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15316, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-23390219, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-25293129
[Journal Article] Missense mutations in the gene encoding prothrombin corresponding to Arg596 cause antithrombin resistance and thrombomodulin resistance2016
- Author(s)
  Takagi Y, Murata M, Kozuka T, Nakata Y, Hasebe R, Tamura S, Takagi A, Matsushita T, Saito H, Kojima T.
- Journal Title
  
  THROMBOSIS AND HAEMOSTASIS
  
  Volume: 116 Issue: 12 Pages: 1022-31
- DOI
  10.1160/th16-03-0223
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16J08029, KAKENHI-PROJECT-26860723, KAKENHI-PROJECT-16K08967, KAKENHI-PROJECT-16K09825
[Journal Article] Progestin isoforms provide different levels of protein S expression in HepG2 cells.2016
- Author(s)
  Kozuka, Toshihiro Tamura, Shogo Kawamura, Nami Nakata, Yukiko Hasebe, Ryo Makiyama, Ayumi Takagi, Yuki Murata, Moe Mizutani, Naoki Takagi, Akira Kojima, Tetsuhito
- Journal Title
  
  Thrombosis research
  
  Volume: 145 Pages: 40-5
- DOI
  10.1016/j.thromres.2016.07.007
- NAID
  120005895232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860723, KAKENHI-PROJECT-16K09825
[Journal Article] 新たな血栓性素因：アンチトロンビンレジスタンス2016
- Author(s)
  小嶋哲人、高木明、村田萌、高木夕希
- Journal Title
  
  日本産婦人科・新生児血液学会誌
  
  Volume: 25 Pages: 66-77
- Data Source
  KAKENHI-PROJECT-16K08967
[Journal Article] Antithrombin resistance: a new mechanism of inherited thrombophilia2015
- Author(s)
  小嶋哲人, 高木明, 村田萌, 高木夕希
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 56 Issue: 6 Pages: 632-638
- DOI
  10.11406/rinketsu.56.632
- NAID
  130005093096
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J03741, KAKENHI-PROJECT-25293129
[Journal Article] Serum syndecan-4 as a possible biomarker in patients with acute pneumonia2015
- Author(s)
  Nikaido T, Tanino Y, Wang X, Sato S, Misa K, Fukuhara N, Sato Y, Fukuhara A, Uematsu M, Suzuki Y, Kojima T, Tanino M, Endo Y, Tsuchiya K, Kawamura I, Frevert C, Munakata M
- Journal Title
  
  J Infect Dis
  
  Volume: 212 Issue: 9 Pages: 1500-1508
- DOI
  10.1093/infdis/jiv234
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08359, KAKENHI-PROJECT-25460596, KAKENHI-PROJECT-26460523, KAKENHI-PROJECT-25293129
[Journal Article] SVA retrotransposition in exon 6 of the coagulation factor IX gene causing severe hemophilia B.2015
- Author(s)
  Nakamura Y, Murata M, Takagi Y, Kozuka T, Nakata Y, Hasebe R, Takagi A, Kitazawa JI, Shima M, Kojima T.
- Journal Title
  
  Int J Hematol
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591421
[Journal Article] アンチトロンビンレジスタンス ―新しい遺伝性血栓性素因―2015
- Author(s)
  小嶋哲人、高木明、村田萌、高木夕希
- Journal Title
  
  臨床血液
  
  Volume: 56 Pages: 632-637
- NAID
  130005093096
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460683
[Journal Article] Increased SPHK2 transcription of human colon cancer cells in serum-depleted culture: the involvement of CREB transcription factor.2015
- Author(s)
  Mizutani N, Omori Y, Tanaka K, Ito H, Takagi A, Kojima T, Nakatochi M, Ogiso H, Kawamoto Y, Nakamura M, Suzuki M, Kyogashima M, Koizumi K, Nozawa Y, Murate T.
- Journal Title
  
  J Cell Biochem
  
  Volume: 116 Issue: 10 Pages: 2227-2238
- DOI
  10.1002/jcb.25173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-26460674, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-26290051
[Journal Article] Increased Acid Ceramidase Expression depends on Upregulation of Androgen-dependent Deubiquitinases, USP2, in a Human Prostate Cancer Cell Line, LNCaP.2015
- Author(s)
  Naoki Mizutani, Minami Inoue, Yukari Omori, Hiromi Ito, Keiko Tamiya-Koizumi, Akira Takagi, Tetsuhito Kojima, Mitsuhiro Nakamura, Soichiro Iwaki, Masahiro Nakatochi, Motoshi Suzuki, Yoshinori Nozawa, Takashi Murate
- Journal Title
  
  J. Biochem.
  
  Volume: 印刷中 Issue: 4 Pages: 309-319
- DOI
  10.1093/jb/mvv039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460203, KAKENHI-PROJECT-26460674, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-26290051
[Journal Article] Development of new laboratory test to evaluate antithrombin resistance in plasma2014
- Author(s)
  Murata M, Takagi A, Suzuki A, Okuyama E, Takagi Y, Ando Y, Kato I, Nakamura Y, Murate T, Matsushita T, Saito H, Kojima T.
- Journal Title
  
  Thromb Res.
  
  Volume: 133 Pages: 293-299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460683
[Journal Article] 1Current venous thromboembolism management and its outcomes in Japan: the nationwide JAVA observational study.2014
- Author(s)
  Nakamura M, Miyata T, Ozeki Y, Takayama M, Komori K, Yamada N, Origasa H, Satokawa H, Maeda H, Tanabe N, Unno N, Shibuya T, Tanemoto K, Kondo K, Kojima T.
- Journal Title
  
  Circ J.
  
  Volume: 78 Pages: 708-717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293129
[Journal Article] RhoF Promotes Murine Marginal Zone B Cell Development.2014
- Author(s)
  Kishimoto M, Matsuda T, Yanase S, Katsumi A, Sezuki N, Ikejiri M, Takagi A, Ikawa M, Kojima T, Kunishima S, Kiyoi H, Naoe T, Matsushita T, Maruyama M
- Journal Title
  
  Nagoya J Med Sci.
  
  Volume: 76 Pages: 293-305
- NAID
  120005468127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293129
[Journal Article] Development of a new laboratory test to evaluate antithrombin resistance in plasma.2014
- Author(s)
  Murata M, Takagi A, Suzuki A, Okuyama E, Takagi Y, Ando Y, Kato I, Nakamura Y, Murate T, Matsushita T, Saito H, Kojima T.
- Journal Title
  
  Thromb Res
  
  Volume: 133 Issue: 2 Pages: 293-298
- DOI
  10.1016/j.thromres.2013.11.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-25461445
[Journal Article] 新たな血栓性素因：アンチトロンビンレジスタンス2014
- Author(s)
  小嶋哲人
- Journal Title
  
  日本検査血液学会雑誌
  
  Volume: 15 Pages: 289-296
- Data Source
  KAKENHI-PROJECT-25293129
[Journal Article] A complex genomic abnormality found in a patient with antithrombin deficiency and autoimmune disease-like symptoms.2014
- Author(s)
  Kato I, Takagi Y, Ando Y, Nakamura Y, Murata M, Takagi A, Murate T, Matsushita T, Nakashima T, Kojima T.
- Journal Title
  
  Int J Hematol
  
  Volume: 100 Issue: 2 Pages: 200-205
- DOI
  10.1007/s12185-014-1596-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-25460683, KAKENHI-PROJECT-25461445
[Journal Article] High prophylactic LMWH dose successfully suppressed hemostatic activation in pregnant woman with a new prpthrombin c.1787G>A mutation.2014
- Author(s)
  Kovac M, Elezovic I, Mikovic V, Djordjevic V, Radojkovic D, Lalic-Cosic S, Murata M, Takagi A, Kojima T
- Journal Title
  
  Thromb Res.
  
  Volume: 135 Issue: 2 Pages: 420-422
- DOI
  10.1016/j.thromres.2014.12.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J03741, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-25460683
[Journal Article] Rhof promotes murine marginal zone B cell development.2014
- Author(s)
  Kishimoto M, Matsuda T, Yanase S, Katsumi A, Suzuki N, Ikejiri M, Takagi A, Ikawa M, Kojima T, Kunishima S, Kiyoi H, Naoe T, Matsushita T, Maruyama M.
- Journal Title
  
  Nagoya J Med Sci
  
  Volume: 76 Pages: 293-305
- NAID
  120005468127
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591421
[Journal Article] Phosphorylated Sp1 is the regulator of DNA-PKcs and DNA ligase IV transcription of daunorubicin-resistant leukemia cell lines2014
- Author(s)
  Nishida Y, Mizutani N, Inoue M, Omori Y, Tamiya-Koizumi K, Takagi A, Kojima T, Suzuki M, Nozawa Y, Minami Y, Ohnishi K, Naoe T, Murate T.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1839 Pages: 265-274
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460674
[Journal Article] Antithrombin- resistant prothrombin Yukuhashi mutation also causes thrombomodulin resistance in fibrinogen clotting but not in protein C activation.2014
- Author(s)
  Takagi Y, Kato I, Ando Y, NakamuraY, Murata M, Takagi A, Murate T, Kojima T
- Journal Title
  
  Thromb Res.
  
  Volume: 134 Issue: 4 Pages: 914-917
- DOI
  10.1016/j.thromres.2014.07.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J03741, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-25460683
[Journal Article] Ribavirin-induced intracellular GTP depletion activates transcription elongation in coagulation Factor VII gene expression2013
- Author(s)
  Atsuo Suzuki, et al.
- Journal Title
  
  Biochemical Journal
  
  Volume: 449 Issue: 1 Pages: 231-239
- DOI
  10.1042/bj20121286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05159, KAKENHI-PROJECT-22590524
[Journal Article] Sphingosine kinase 1 expression is downregulated during differentiation of Friend cells due to decreased c-MYB.2013
- Author(s)
  Mizutani N, Kobayashi M, Sobue S, Ichihara M, Ito H, Tanaka K, Iwaki S,Fujii S,Ito Y, Tamiya-Koizumi K, Takagi A, Kojima T, Naoe T, Suzuki M, Nakamura M, Banno Y, Nozawa Y, Murate T.
- Journal Title
  
  Biochimica et Biophysica Acta -Molecular Cell Research
  
  Volume: 1833 Issue: 5 Pages: 1006-16
- DOI
  10.1016/j.bbamcr.2013.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590139, KAKENHI-PROJECT-23590667, KAKENHI-PROJECT-24590185, KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-24790164
[Journal Article] A novel prothrombin mutation in two families with prominent thrombophilia--the first cases of antithrombin resistance in a Caucasian population.2013
- Author(s)
  Djordjevic V, Kovac M, Miljic P, Murata M, Takagi A, Pruner I, Francuski D, Kojima T, Radojkovic D.
- Journal Title
  
  J Thromb Haemost
  
  Volume: 11 Issue: 10 Pages: 1936-1939
- DOI
  10.1111/jth.12367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25460683
[Journal Article] Establishment of mouse model of MYH9 disorders: heterozygous R702C mutation provokes macrothrombocytopenia with leukocyte inclusion bodies, renal glomerulosclerosis and hearing disability.2013
- Author(s)
  Suzuki N, Kunishima S, Ikejiri M, Maruyama S, Sone M, Takagi A, Ikawa M, Okabe M, Kojima T, Saito H, Naoe T, Matsushita T.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 8 Pages: 41-50
- DOI
  10.1371/journal.pone.0071187
- NAID
  120006957397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591429, KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-24591421, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293129
[Journal Article] Molecular mechanisms of syndecan-4 upregulation by TNF-α in the endothelium-like EAhy926 cells.2013
- Author(s)
  Okuyama E, Suzuki A, Murata M, Ando Y, Kato I, Takagi Y, Takagi A, Murate T, Saito H, Kojima T.
- Journal Title
  
  J Biochem
  
  Volume: 154 Issue: 1 Pages: 41-50
- DOI
  10.1093/jb/mvt024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591421
[Journal Article] Comparison of the efficacy of ribavirin plus peginterferon alfa-2b for chronic hepatitis C infection in patients with and without coagulation disorders.2013
- Author(s)
  Honda T, Katano Y, Kuzuya T, Hayashi K, Ishigami M, Itoh A, Hirooka Y, Nakano I, Ishikawa T, Toyoda H, Kumada T, Yamamoto K, Matsushita T, Kojima T, Takamatsu J, Goto H
- Journal Title
  
  J Med Virol.
  
  Volume: 85(2) Issue: 2 Pages: 228-234
- DOI
  10.1002/jmv.23444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-23590970, KAKENHI-PROJECT-23592689, KAKENHI-PROJECT-24591421
[Journal Article] Impact of antithrombin deficiency on efficacy of edoxaban and antithrombin-dependent anticoagulants, fondaparinux, enoxaparin, and heparin.2013
- Author(s)
  Fukuda T, Kamisato C, Honda Y, Matsushita T, Kojima T, Furugohri T, Morishima Y, Shibano T
- Journal Title
  
  Thromb Res.
  
  Volume: 131 Issue: 6 Pages: 540-546
- DOI
  10.1016/j.thromres.2013.04.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293129
[Journal Article] Ribavirin-induced intracellular GTP depletion activates transcription elongation in coagulation factor VII gene expression2013
- Author(s)
  Suzuki A, Miyawaki Y, Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Takagi A, Murate T, Saito H, Kojima T
- Journal Title
  
  Biochemical J
  
  Volume: 449(1) Pages: 231-239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Role of down-regulated neutral ceramidase during all-trans retinoic acid induced neuronal differentiation in SH-SY5Y neuroblastoma cells2012
- Author(s)
  Kouji Tanaka
- Journal Title
  
  J.Biochem.
  
  Volume: (印刷中) Issue: 6 Pages: 611-620
- DOI
  10.1093/jb/mvs033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790156, KAKENHI-PROJECT-22590139, KAKENHI-PUBLICLY-23107712, KAKENHI-PROJECT-23590667, KAKENHI-PROJECT-23659664, KAKENHI-PROJECT-24590364, KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-24790164
[Journal Article] Thrombosis from a Prothrombin Mutastion Conveying Antithrombin Resistance2012
- Author(s)
  Yuhri Miyawaki, Atsuo Sizuki, Junko Fujita, Asuka Maki, Eriko Okuyama, Moe Murata, Akira Takagi, Takashi Murate, Shinji Kunishima, Michio Sakata, Kohji Okamoto, Tadashi Matsushita, Tomoki Naoe, Hidehiko Saito, Tetsuhito Kojima
- Journal Title
  
  The NEW ENGLAND JOURNAL of MEDICINE
  
  Volume: 366巻 Pages: 2390-2396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659114
[Journal Article] A novel ENG mutation causing impaired co-translational processing of endoglin associated with hereditary hemorrhagic telangiestasia2012
- Author(s)
  Atsuo Suzuki
- Journal Title
  
  Thrombosis Research
  
  Volume: (in press) Issue: 5 Pages: e200-e208
- DOI
  10.1016/j.thromres.2011.12.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05159, KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-22591059
[Journal Article] Thrombosis from a prothrombin mutation conveying antithrombin resistance2012
- Author(s)
  Miyawaki Y, Suzuki A, Fujita J, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Kunishima S, Sakai M, Okamoto K, Matsushita T, Naoe T, Saito H, Kojima K
- Journal Title
  
  N Engl J Med
  
  Volume: 366 Pages: 2390-2396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Thrombosis from a prothrombin mutation conveying antithrombin resistance.2012
- Author(s)
  Miyawaki Y, Suzuki A, Fujita J, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Kunishima S, Sakai M, Okamoto K, Matsushita T, Naoe T, Saito H, Kojima T
- Journal Title
  
  N Engl J Med.
  
  Volume: 366 Issue: 25 Pages: 2390-2396
- DOI
  10.1056/nejmoa1201994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-22591059, KAKENHI-PROJECT-22591755, KAKENHI-PROJECT-22659114, KAKENHI-PROJECT-23591429
[Journal Article] A survey of the clinical course and management of Japanese patients deficient in natural anticoagulants.2012
- Author(s)
  Yokoyama k, Kojima T, Sakata Y, Kawasaki T, Tsuji H, Miyata T, Okamoto S, Murata M
- Journal Title
  
  Clin Appl Thromb Hemost
  
  Volume: 18(5) Pages: 506-513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] A novel ENG mutation causing impaired co-translational processing of endoglin associated with hereditary hemorrhagic telangiectasia.2012
- Author(s)
  Suzuki A, Nakashima D, Miyawaki Y, Fujita J, Maki A, Fujimori Y, Takagi A, Murate T, Teranishi M, Matsushita T, Saito H, Kojima T
- Journal Title
  
  Thromb Res
  
  Volume: 129(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] A possible mechanismfor Inv22-related F8 large deletions in severe hemophilia A patients with high responding factor VIII inhibitors2012
- Author(s)
  J. Fujita, Y. Miyawaki, A. Suzuki, et al.
- Journal Title
  
  Journal of Thrombosis and Haemostasis
  
  Volume: 10 Issue: 10 Pages: 2099-2107
- DOI
  10.1111/j.1538-7836.2012.04897.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05159, KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-22591059
[Journal Article] Transcriptional regulation of neutral sphingomyelinase 2 in all-trans retinoic acid-treated human breast cancer cell line, MCF-7.2012
- Author(s)
  Ito H
- Journal Title
  
  J Biochem.
  
  Volume: 151 Issue: 6 Pages: 599-610
- DOI
  10.1093/jb/mvs037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790532, KAKENHI-PUBLICLY-23107712, KAKENHI-PROJECT-23590667, KAKENHI-PROJECT-23659664, KAKENHI-PROJECT-24590185, KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-24780125
[Journal Article] The author reply2012
- Author(s)
  Matsushita T, Saito H, Kojima T
- Journal Title
  
  N Engl J Med
  
  Volume: 367 Pages: 1069-1070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Syndecan-4 Regulates Early Neutrophil Migration and Pulmonary Inflammation in Response to Lipopolysaccharide.2012
- Author(s)
  Tanino Y, Chang MY, Wang X, Gill SE, Skerrett S, McGuire JK, Sato S, Nikaido T, KojimaT, Munakata M, Mongovin S, Parks WC, Martin TR, Wight TN, Charles W
- Journal Title
  
  Am J Respir Cell Mol Biol.
  
  Volume: 47(2) Issue: 2 Pages: 196-202
- DOI
  10.1165/rcmb.2011-0294oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] A possible mechanism for Inv22-related F8 large deletions in severe hemophilia a patients with high responding factor VIII inhibitors2012
- Author(s)
  Fujita J, Miyawaki Y, Suzuki A, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Suzuki N, Matsushita T, Saito H, Kojima T
- Journal Title
  
  J Thromb Haemost
  
  Volume: 10(10) Pages: 2099-2107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Venous thromboembolism and a race-specific genetic variation, protein S K196E, in Japanese.2011
- Author(s)
  Miyata T, Hamasaki N, Wada H, Kojima T
- Journal Title
  
  J Thromb Haemost
  
  Volume: (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Historical perspective and future direction of coagulation research2011
- Author(s)
  H Saito, T Matsushita, T Kojima
- Journal Title
  
  J Thromb Haemost
  
  Volume: Suppl 1 Pages: 352-363
- DOI
  10.1111/j.1538-7836.2011.04362.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Syndecan-4 prevents cardiac rupture and dysfunction after myocardial infarction2011
- Author(s)
  Y Matsui, M Ikesue, K Danzaki, J Morimoto, M Sato, S Tanaka, T Kojima, H Tsutsui, T Uede
- Journal Title
  
  Circ Res
  
  Volume: 108(11) Pages: 1328-1339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Syndecan-4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cell proliferation and vascular progenitor cell mobilization.2011
- Author(s)
  Ikesue M, Matsui Y, Ohta D, Danzaki K, Ito K, Kanayama M, Kurotaki D, Morimoto J, Kojima T, Tsutsui H, Uede T
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(5) Pages: 1066-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Life-threatening hemorrhage and prolonged wound healing are remarkable phenotypes manifested by complete plasminogen activator inhibitor-1 deficiency in humans2011
- Author(s)
  T Iwaki, A Tanaka, Y Miyawaki, A Suzuki, T Kobayashi, J Takamatsu, T Matsushita, K Umemura, T Urano, T Kojima, T Terao, N Kanayama
- Journal Title
  
  J Thromb Haemost
  
  Volume: 9(6) Issue: 6 Pages: 1200-1206
- DOI
  10.1111/j.1538-7836.2011.04288.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-22590826, KAKENHI-PROJECT-22591059, KAKENHI-PROJECT-22790247
[Journal Article] Historical perspective and future direction of coagulation research2011
- Author(s)
  Saito H, Matsushita T, Kojima T
- Journal Title
  
  J Thromb Haemost
  
  Volume: Suppl 1 Pages: 352-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Virus-Associated Hemophagocytic Syndrome Caused by Pandemic Swine-Origin Influenza A (H1N1) in a Patient After Unrelated Bone Marrow Transplantation2011
- Author(s)
  A Katsumi, T Nishida, M Murata, S Terakura, K Shimada, S Saito, M Kobayashi, A Kodaira, S Shibata, I Oda, T Yagi, H Kiyoi, T Matsushita, T Kojima, T Naoe
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 51 Issue: 1 Pages: 63-65
- DOI
  10.3960/jslrt.51.63
- NAID
  10028239126
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Syndecan-4 prevents cardiac rupture and dysfunction after myocardial infarction.2011
- Author(s)
  Matsui Y, Ikesue M, Danzaki K, Morimoto J, Sato M, Tanaka S, Kojima T, Tsutsui H, Uede T
- Journal Title
  
  Circ Res
  
  Volume: 108(11) Pages: 1328-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Syndecan-4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cell proliferation and vascular progenitor cell mobilization2011
- Author(s)
  Ikesue M., et al
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31 Issue: 5 Pages: 1066-1074
- DOI
  10.1161/atvbaha.110.217703
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117004, KAKENHI-PROJECT-21390236, KAKENHI-PROJECT-22590524
[Journal Article] Life-threatening hemorrhage and prolonged wound healing are remarkable phenotypes manifested by complete plasminogen activator inhibitor-1 deficiency in humans2011
- Author(s)
  Iwaki T, Tanaka A, Miyawaki Y, Suzuki A, Kobayashi T, Takamatsu J, Matsushita T, Umemura K, Urano T, Kojima T, Terao T, Kanayama N
- Journal Title
  
  J Thromb Haemost
  
  Volume: 9(6) Pages: 1200-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation2010
- Author(s)
  Y Miyawaki, A Suzuki, Y Fujimori, A Takagi, T Murate, N Suzuki, A Katsumi, T Naoe, K Yamamoto, T Matsushita, J Takamatsu, T Kojima
- Journal Title
  
  Int J Hematol
  
  Volume: 92(2) Pages: 405-408
- NAID
  10026712691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Down-regulation of PROS1 gene expression by 17.-estradiol via estrogen receptor . (ER.)-Sp1 interaction recruiting receptor-interacting protein140 and the corepressor-HDAC3 complex.2010
- Author(s)
  A Suzuki, N Sanda, Y Miyawaki, Y Fujimori, T Yamada, A Takagi, T Murate, H Saito, T Kojima
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285(18) Pages: 13444-13453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation.2010
- Author(s)
  Miyawaki Y, Suzuki A, Fujimori Y, Takagi A, Murate T, Suzuki N, Katsumi A, Naoe T, Yamamoto K, Matsushita T, Takamatsu J, Kojima T.
- Journal Title
  
  International Journal of Hematology
  
  Volume: 92 Pages: 405-408
- NAID
  10026712691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] Activated protein C resistance in the Japanese population due to homozygosity for the factor V R2 haplotype2010
- Author(s)
  H Okada, Y Toyoda, A Takagi, H Saito, T Kojima, T Yamazaki
- Journal Title
  
  Int J Hematol
  
  Volume: 91(3) Pages: 549-550
- NAID
  10026401575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation.2010
- Author(s)
  Y Miyawaki, T Kojima, et al.
- Journal Title
  
  Int J Hematol.
  
  Volume: 92 Pages: 405-408
- NAID
  10026712691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] A novel splice site mutation in intron C of PROS1 leads to markedly reduced mutant mRNA level, absence of thrombin-sensitive region, and impaired secretion and cofactor activity of mutant protein S.2010
- Author(s)
  Okada H, Kunishima S, Hamaguchi M, Takagi A, Yamamoto K, Takamatsu J, Matsushita T, Saito H, Kojima T, Yamazaki T.
- Journal Title
  
  Thrombosis Research
  
  Volume: 125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] A novel splice site mutation in intron C of PROS1 leads to markedly reduced mutant mRNA level, absence of thrombin-sensitive region, and impaired secretion and cofactor activity of mutant protein S.2010
- Author(s)
  Okada H, Kunishima S, Hamaguchi M, Takagi A, Yamamoto K, Takamatsu J, Matsushita T, Saito H, Kojima T, Yamazaki T.
- Journal Title
  
  Thrombosis Research 125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] A novel splice site mutation in intron C of PROSl leads to markedly reduced mutant mRNA level, absence of thrombin-sensitive region, and impaired secretion and cofactor activity of mutant protein S.2010
- Author(s)
  H Okada, T Kojima, et al.
- Journal Title
  
  Thromb Res.
  
  Volume: 125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Down-regulation of PROSl gene expression by 17β-estradiol via estrogen receptor α(ERα)-Splinteraction recruiting receptor-interactingng protein140 and the corepressor-HDAC3 complex.2010
- Author(s)
  A Suzuki, T Kojima, et al.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285 Pages: 13444-13453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] A novel splice site mutation in intron C of PROS1 leads to markedly reduced mutant mRNA level, absence of thrombin-sensitive region, and impaired secretion and cofactor activity of mutant protein S.2010
- Author(s)
  H Okada, S Kunishima, M Hamaguchi, A Takagi, K Yamamoto, J Takamatsu, T Matsushita, H Saito, T Kojima, T Yamazaki
- Journal Title
  
  Thromb Res
  
  Volume: 125(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590524
[Journal Article] Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation.2010
- Author(s)
  Miyawaki Y, Suzuki A, Fujimori Y, Takagi A, Murate T, Suzuki N, Katsumi A, Naoe T, Yamamoto K, Matsushita T, Takamatsu J, Kojima T.
- Journal Title
  
  International Journal of Hematology 92
  
  Pages: 405-408
- NAID
  10026712691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] A novel cholesterol absorption inhibitor, ezetimibe, decreases adipose-derived and vascular PAI-1 expression in vivo.2009
- Author(s)
  Yamamoto K, Shibayama S, Takeshita K, Kojima T, Takamatsu J.
- Journal Title
  
  Thrombosis Research 124
  
  Pages: 644-645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] Stress-induced PAI-1 expression is suppressed by pitavastatin in vivo.2009
- Author(s)
  Yamamoto K, Takeshita K, Kojima T, Takamatsu J.
- Journal Title
  
  International Journal of Hematology 89
  
  Pages: 553-554
- NAID
  10025161609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] T Murate : Implications of sphingosine kinase 1 expression level for the cellular sphingolipid rheostat: relevance as a marker for daunorubicin sensitivity of leukemia cells2008
- Author(s)
  S Sobue, S Nemoto, M Murakami, H Ito, A Kimura, S Gao, A Furuhata, A Takagi, T Kojima, M Nakamura, M Ito, M Suzuki, Y Banno, Y Nozawa
- Journal Title
  
  Int J Hematol 87(3)
  
  Pages: 266-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Syndecan-4 protects against osteopontin-mediated acute hepatic injury by masking functiona1 domains of osteopontin.2008
- Author(s)
  S. Kon, T. Kojima, et. al.
- Journal Title
  
  Thromb Haemost 205
  
  Pages: 25-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Skewed X chromosome inactivation in fratemal female twins results in moderately severe and mild haemophilia B.2008
- Author(s)
  K. Okumura, T. Kojima, et al.
- Journal Title
  
  Haemophilia 14
  
  Pages: 1088-1093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged-to-alanine-scanning mutagenesis.2008
- Author(s)
  T. Nakayama, T. Kojima, et al.
- Journal Title
  
  Int J Hematol. 87
  
  Pages: 363-370
- NAID
  10025158532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Skewed X chromosome inactivation in fraternal female twins results in moderately severe and mild haemophilia B2008
- Author(s)
  K Okumura, Y Fujimori, A Takagi, T Murate, M Ozeki, K Yamamoto, A Katsumi, T Matsushita, T Naoe, and T Kojima
- Journal Title
  
  Haemophilia 14(5)
  
  Pages: 1088-1093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Mufational analysis of SOS1 in acute myeloid leukemia.2008
- Author(s)
  R. Tanizaki, T. Kojima, et al.
- Journal Title
  
  Int J Hematol. 88
  
  Pages: 460-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Prognostic implication and biological roles of RhoH in acute myeloid leukaemia2008
- Author(s)
  T Iwasaki, A Katsumi, H Kiyoi, R Tanizaki, Y Ishikawa, K Ozeki, M Kobayashi, A Abe, T Matsushita, T Watanabe, M Amano, T Kojima, K Kaibuchi, T Naoe
- Journal Title
  
  Eur J Haematol 81(6)
  
  Pages: 454-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Molecular Defects Associated with Antithrombin Deficiency and Dilated Cardiomyopathy in a Japanese Patient2008
- Author(s)
  Y Fujimori, H Okimatsu, T Kashiwagi, N Sanda, K Okumura, A Takagi, K Nagata, T Murate, A Uchida, K Node, H Saito and T Kojima
- Journal Title
  
  Inter Med. 47(10)
  
  Pages: 925-931
- NAID
  130000078680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged-to-alanine-scanning mutagenesis2008
- Author(s)
  T Nakayama, T Matsushita, K Yamamoto, N Mutsuga, T Kojima, A Katsumi, N Nakao, JE Sadler, T Naoe, H Saito
- Journal Title
  
  Int J Hematol 87(4)
  
  Pages: 363-370
- NAID
  10025158532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] A neonate with homozygous protein C deficiency with a homozygous Arg178Trp mutation2008
- Author(s)
  F Ozlu, M Kyotani, E Taskin, K Ozcan, T Kojima, T Matsushita, H Yapicioglu, A Takagi, I Sasmaz, M Satar, and N Narli
- Journal Title
  
  J Pediatr Hematol Oncol 30
  
  Pages: 608-611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] v-Src oncogene product increases sphingosine kinase 1 expression through mRNA stabilization : alteration of AU-rich element-binding proteins.2008
- Author(s)
  S. Sobue, T. Kojima., et al.
- Journal Title
  
  Oncogene. 27
  
  Pages: 6023-6033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Mutational analysis of SOS1 in acute myeloid eukemia2008
- Author(s)
  Tanizaki, A Katsumi, H Kiyoi, S unishima, T Iwasaki, Y Ishikawa, M obayashi, A Abe, T Matsushita, T Watanabe, Kojima, K Kaibuchi, S Kojima, T Naoe
- Journal Title
  
  Int J Hematol 88(4)
  
  Pages: 460-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] L1503R is a member of group I mutation and has dominant-negative effect on secretion of full-length VWF multimers: an analysis of two patients with type 2A von Willebrand disease.2008
- Author(s)
  T Kashiwagi, T Mstsushita, Y Ito, K Hirashima, N Sanda, Y Fujimori, T Yamada, K Okumura, A Takagi, T Murate, A Katsumi, J Takamatsu, K Yamamoto, T Naoe, T Kojima
- Journal Title
  
  Haemophilia 14(3)
  
  Pages: 556-563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Implications of sphingosine kinase 1 expression level for the cellular sphingolipid rheosfat : relevance as a marker for daunonibicin sensitivity of leukemia cells.2008
- Author(s)
  S. Sobue, T. Kojima., et al.
- Journal Title
  
  Int J Hematol 87
  
  Pages: 266-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged to Alanine scanning mutagenesis.2008
- Author(s)
  Nakayama T, Matsushita T, Kojima T, Yamamoto K, Sadler EJ, Naoe T, Saito H.
- Journal Title
  
  International Journal of Hematology 87
  
  Pages: 363-370
- NAID
  10025158532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591148
[Journal Article] Molecular Defects Associated with Antithrombin Deficiency and Dilated Cardiomyopathy in a Japanese Patient.2008
- Author(s)
  Y. Pujimori, T. Kojima., et al.
- Journal Title
  
  Inter Med. 47
  
  Pages: 925-931
- NAID
  130000078680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Prognostic implication and biological roles of RhoH in acute myeloid leukaemia.2008
- Author(s)
  T. Iwasaki, T. Kojima, et al.
- Journal Title
  
  Eur J Haematol. 81
  
  Pages: 454-460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] v-Src oncogene product increases sphingosine kinase 1 expression through mRNA stabilization: alteration of AU-rich element-binding proteins2008
- Author(s)
  S Sobue, M Murakami, Y Banno, H Ito, A Kimura, S Gao, A Furuhata, A Takagi, T Kojima, M Suzuki, Y Nozawa, T Murate
- Journal Title
  
  Oncogene 27(46)
  
  Pages: 6023-6033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] A neonate with homozygous protein C deficiency with a homozygous Argl78Trp mutation.2008
- Author(s)
  F. Ozlu, T. Kojima, et al.
- Journal Title
  
  J Pediatr Hematol Oncol 30
  
  Pages: 608-611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] An Sp1 binding site mutation of the PROSl promoter in a patient with protein S deficiency.2007
- Author(s)
  N. Sanda, T. Kojima, et. al.
- Journal Title
  
  Br J Haematol 138
  
  Pages: 663-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Pitavastatin attenuates the upregulation of tissue factor in restraint-stressed mice.2007
- Author(s)
  Yamamoto K, Kojima T, Takeshita K, Matsushita T, Takamatsu J.
- Journal Title
  
  Thrombosis Research 120
  
  Pages: 143-144
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591053
[Journal Article] Mechanism of vitamin D3-induced transcription of phospholipase D1 in HaCat human keratinocytes2007
- Author(s)
  R Kikuchi, S Sobue, M Murakami, H Ito, A Kimura, T Iwasaki, S Shibayama, A Takagi, T Kojima, M Suzuki, Y Banno, Y Nozawa, T Murate
- Journal Title
  
  FEBS Lett 581(9)
  
  Pages: 1800-1804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Wilms' tumor 1 message and protein expression in bone marrow failure syndrome and acute leukemia.2007
- Author(s)
  T. Iwasaki, T. Kojima, et. al.
- Journal Title
  
  Pathol Int 57
  
  Pages: 645-651
- NAID
  10021233832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Molecular basis of antithrombin deficiency in four Japanese patients with antithrombin gene abnormalities including two novel mutations.2007
- Author(s)
  M. Kyotani, T. Kojima, et. al.
- Journal Title
  
  Am J Hemato1 82
  
  Pages: 702-705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] A large deletion of the PROSl gene in a deep vein thrombosis patient with protein S deficiency.2007
- Author(s)
  T. Yin T. Kojima, et. al.
- Journal Title
  
  Thromb Haemost 98
  
  Pages: 783-789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Wilms' tumor 1 message and protein expression in bone marrow failure syndrome and acute leukemia2007
- Author(s)
  T Iwasaki, C Sugisaki, K Nagata, K Takagi, A Takagi, T Kojima, M Ito, S Nakamura, T Naoe, T Murate
- Journal Title
  
  Pathol Int 57(10)
  
  Pages: 645-651
- NAID
  10021233832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Pitavastatin attenuates the upregulation of tissue factor in restraint-stressed mice2007
- Author(s)
  Yamamoto, K, Kojima, T. Takeshita, K. Matsushita, T. Takamatsu, J
- Journal Title
  
  Thrombosis Research Volume120, number1
  
  Pages: 143-144
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591053
[Journal Article] RET signaling-induced SPHK1 gene expression plays a role in both GDNF-induced differentiation and MEN2-type oncogenesis2007
- Author(s)
  Murakami, M Ichihara, S Sobue, R Kikuchi, H Ito, A Kimura, T Iwasaki, A Takagi, T Kojima, M Takahashi, M Suzuki, Y Banno, Y Nozawa, T Murate1
- Journal Title
  
  J Neurochem 102(5)
  
  Pages: 1585-1594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Mechanism of vitamin D3-induced transcription of phospholipase Dl in HaCat human keratinocytes.2007
- Author(s)
  R. Kikuchi, T. Kojima, et. al.
- Journal Title
  
  FEBS Lett 581
  
  Pages: 1800-1804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Molecular basis of antithrombin deficiency in four Japanese patients with antithrombin gene abnormalities including two novel mutations2007
- Author(s)
  M Kyotani, K Okumura, A Takagi, T Murate, K Yamamoto, T Matsushita, M Sugimura, N Kanayama, T Kobayashi, H Saito, T Kojima
- Journal Title
  
  Am J Hematol 82(2)
  
  Pages: 702-705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] An Sp1 binding site mutation of the PROS1 promoter in a patient with protein S deficiency2007
- Author(s)
  N Sanda, Y Fujimori, T Kashiwagi, A Takagi, T Murate, E Mizutani, T Matsushita, T Naoe, T Kojima
- Journal Title
  
  Br J Haematol 138(5)
  
  Pages: 663-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] A large deletion of the PROS1 gene in a deep vein thrombosis patient with protein S deficiency2007
- Author(s)
  T Yin, S Takeshita, Y Sato, T Sakata, Y Shin, S Honda, T Kawasaki, H Tsuji, T Kojima, S Madoiwa, Y Sakata, M Murata, Y Ikeda, T Miyata
- Journal Title
  
  Thromb Haemost 98(4)
  
  Pages: 783-789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] RET signaling-induced SPHKl gene expression plays a role in both GDNF-induced differentiation and MEN2-type oncogenesis2007
- Author(s)
  M. Murakami, T. Kojima, et. al.
- Journal Title
  
  J Neurochem 102
  
  Pages: 1585-1594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590553
[Journal Article] Obesity enhances the induction of plasminogen activator inhibitor-1 by restraint stress : a possible mechanism of stress-induced renal fibrin deposition in obese mice.2005
- Author(s)
  Yamamoto K, Kojima T, Adachi T, Hayashi M, Matsushita T, Takamatsu J, Loskutoff DJ, Saito H.
- Journal Title
  
  Journal of Thrombosis and Haemostasis 3巻・7号
  
  Pages: 1495-1502
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590934
[Journal Article] Transcription factor specificity protein 1 (Sp1) is the main regulator of nerve growth factor-induced sphingosine kinase 1 gene expression of the rat pheochromocytoma cell line, PC12.2005
- Author(s)
  Sobue S, Hagiwara K, Banno Y, Tamiya-Koizumt K, Suzuki M, Takagi A, Kojima T, Asano H, Nozawa Y, Murate T.
- Journal Title
  
  J Neurochem. 95(4)
  
  Pages: 940-949
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590453
[Journal Article] Obesity enhances the induction of plasminogen activator inhibitor-1 by restraint stress : a possible mechanism of stress-induced renal fibrin deposition. In obese mice.2005
- Author(s)
  Yamamoto K, Kojima T, Adachi T, Hayashi M, Matsushita T, Takamatsu J, Loskutoff DJ, Saito H.
- Journal Title
  
  Journal of Thrombosis and Haemostasis Volume 3 - number 7
  
  Pages: 1495-1502
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590934
[Journal Article] AT/D併用によるエンドトキシン誘発臓器傷害の改善効果-Antithrombin/danaparoid sodiumの抗凝固薬としての位置付け2004
- Author(s)
  小嶋哲人
- Journal Title
  
  日本集中治療医学会雑誌 11(13)
  
  Pages: 174-176
- Data Source
  KAKENHI-PROJECT-15591000
[Patent] 血栓症のリスク検査法2013
- Inventor(s)
  高木明、小嶋哲人、高木夕希、村田萌
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-182541
- Filing Date
  2013-09-03
- Data Source
  KAKENHI-PROJECT-25293129
[Patent] 凝固因子として作用する異常トロンビンのためのトロンビン不活化動態測定方法2013
- Inventor(s)
  高木　明、小嶋哲人、松下　正
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-04-01
- Acquisition Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-25293129
[Patent] 血栓症のリスク検査法2013
- Inventor(s)
  高木明、小嶋哲人、高木夕希、村田萌
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-07-17
- Data Source
  KAKENHI-PROJECT-25460683
[Patent] 凝固因子として作用する異常トロンビンのためのトロンビン不活化動態測定方法及び試験方法、並びに、ポリヌクレオチド2010
- Inventor(s)
  高木明, 小嶋哲人, 松下正
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Number
  2010-289686
- Filing Date
  2010-12-27
- Data Source
  KAKENHI-PROJECT-22659114
[Patent] 凝固因子として作用する異常トロンビンのためのトロンビン不活化動態測定方法及び試験方法、並びに、ポリヌクレオチド2010
- Inventor(s)
  高木明, 小嶋哲人, 松下正
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Industrial Property Number
  2010-289686
- Filing Date
  2010-12-27
- Data Source
  KAKENHI-PROJECT-22590524
[Patent] 凝固因子として作用する異常トロンビンのためのトロンビン不活化動態測定方法及び試験方法、並びに、ポリヌクレオチド2010
- Inventor(s)
  高木明、小嶋哲人、松下正
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Filing Date
  2010-12-27
- Data Source
  KAKENHI-PROJECT-22590524
[Patent] 血液凝固第VII因子プロモーターの活性化剤及びその利用2007
- Inventor(s)
  本田隆小嶋哲人, ら
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Industrial Property Number
  2007-220451
- Filing Date
  2007-08-27
- Data Source
  KAKENHI-PROJECT-19590553
[Patent] 血液凝固第VII 因子プロモーターの活性化剤及びその利用2007
- Inventor(s)
  本多隆、高松純樹、豊田秀徳、山本晃士、後藤秀実、小嶋哲人
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Filing Date
  2007-08-27
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] Genetic Abnormalities of Japanese Patient with Symptomatic- and Asymptomatic-dysfibrinogenemia2019
- Author(s)
  Y. Hattori, S. Tamura, N. Suzuki, M. Kakihara, S. Suzuki, K. Odaira, M. Tokoro, F. Hayakawa, S. Okamoto, T. Kanematsu, T. Matsushita, T. Kojima
- Organizer
  ISTH2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] 特発性血小板減少性紫斑病の病勢に対し，サイトメガロウイルス再活性化の関与が疑われた 2 例2019
- Author(s)
  兼松毅，鈴木伸明，岡本修一，鈴木敦夫，川上萌，三田直美，田村彰吾，小嶋哲人，清井仁，松下正
- Organizer
  第41回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] トロンビン Na binding regionのミスセンス変異は多くがアンチトロンビン抵抗性を示すが、凝固活性も低下する2019
- Author(s)
  田村彰吾、川上萌、勝見章、高木明、早川文彦、小嶋哲人
- Organizer
  トロンビン Na binding regionのミスセンス変異は多くがアンチトロンビン抵抗性を示すが、凝固活性も低下する
- Invited
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] F9 c.87A>G is a Double-faced Deleterious Mutation which Causes a Synonymous and Inframed-mutant FIX due to an Aberrant mRNA Splicing2019
- Author(s)
  K. Odaira, S. Tamura, N. Suzuki, M. Kakihara, Y. Hattori, M. Tokoro, S. Suzuki, A. Takagi, A. Katsumi, F. Hayakawa, S. Okamoto, A. Suzuki, T. Kanematsu, T. Matsushita, T. Kojima
- Organizer
  ISTH2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] 新規伸長型変異を認めた先天性血液凝固第 XI 因子欠乏症の 1 例2019
- Author(s)
  早川友梨，田村彰吾，鈴木伸明，大平晃也，垣原美紗樹，服部有那，所真昼，河島史華，鈴木幸子，早川文彦，高木明，岡本修一，兼松毅，松下正，小嶋哲人
- Organizer
  第41回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] 先天性凝固異常症の遺伝子解析　「解析のStrategyとPitfall」2019
- Author(s)
  田村彰吾、高木明、早川文彦、小嶋哲人
- Organizer
  第20回日本検査血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] An Inv22-like F8 Inverted Disruption in Severe Hemophilia a Brothers Possibly Occurring from Template Switching between Sister Chromatids2019
- Author(s)
  M. Kakihara, S. Tamura, M. Tokoro, K. Odaira, Y. Hattori, S. Suzuki, F. Hayakawa, M. Ogawa, T. Kanematsu, N. Suzuki, T. Matsushita, T. Kojima
- Organizer
  ISTH2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] A Complex F8 Rearrangement Associated with Template Switching and int1h-related Homologous Recombination in a Patient with Severe Hemophilia A2019
- Author(s)
  M. Tokoro, S. Tamura, N. Suzuki, M. Kakihara, Y. Hattori, K. Odaira, S. Suzuki, A. Takagi, F. Hayakawa, S. Okamoto, T. Kanematsu, T. Matsushita, T. Kojima
- Organizer
  ISTH2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] F9 サイレント変異 c.87A ＞ G(p.Thr29 =)に起因するスプライシング異常の分子病態解析2019
- Author(s)
  大平晃也，田村彰吾，所真昼，垣原美紗樹，服部有那，鈴木幸子，高木明，早川文彦，岡本修一，兼松毅，鈴木伸明，松下正，小嶋哲人
- Organizer
  第41回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] 産科関連静脈血栓症における血栓性素因検索 -名古屋大学医学部附属病院における症例第 2 報-2019
- Author(s)
  鈴木幸子，垣原美紗樹，服部有那，大平晃也，所真昼，河島史華，早川友梨，岡本修一，兼松毅，中野知子，今井健史，牛田貴文，森山佳則，小谷友美，鈴木伸明，田村彰吾，早川文彦，小嶋哲人，松下正
- Organizer
  第41回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] int1h-1 を介した組換えではあるが Inv1 ではなく F8 イントロン 1 での複雑な大規模欠失挿入変異による重症血友病 A2019
- Author(s)
  所真昼，田村彰吾，鈴木伸明，垣原美紗樹，服部有那，大平晃也，鈴木幸子，高木明，早川文彦，岡本修一，兼松毅，松下正，小嶋哲人
- Organizer
  第41回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] プロトロンビン R593L マウスの作製と解析2019
- Author(s)
  鈴木伸明，鈴木敦夫，鈴木幸子，田村彰吾，高木明，小嶋哲人，松下正
- Organizer
  第41回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] Molecular genetic analysis of dysfibrinogenemia including novel mutations with thrombosis2018
- Author(s)
  Yuna Hattori, Shogo Tamura, Misaki Kakihara, Sachiko Suzuki, Koya Odaira, Mahiru Tokoro, Humihiko Hayakawa, Tsuyoshi Kanemetsu, Nobuaki Suzuki, Tadashi Matsushita, Tetsuhito Kojima
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] 血漿検体測定を目指したアンチトロンビン抵抗性凝固第X因子検出法の構築2018
- Author(s)
  田村彰吾、藤岡亮也、服部有那、垣原美紗樹、鈴木幸子、高木夕希、高木明、小嶋哲人
- Organizer
  第19回日本検査血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] スプライシング異常を引き起こす血液凝固第IX遺伝子サイレント変異・血友病Bの分子病態解析2018
- Author(s)
  大平晃也、田村彰吾、坂根寛人、所真昼、垣原美紗樹、服部有那、橋本恵梨華、鈴木幸子、高木夕希、高木明、兼松毅、岸本磨由子、鈴木伸明、松下正、小嶋哲人
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] Functional analysis of a variant fibrinogen from dysfibrinogenemia patient with cerebral infarction2018
- Author(s)
  Hattori Y, Takagi Y, Kakihara M, Suzuki S, Odaira K, Tokoro M, Tamura S, Suzuki N, Matushita T, Kojima T
- Organizer
  APSTH2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] 血液凝固第V因子欠乏症を合併する血友病 A 症例:第2報・凝血学的評価2018
- Author(s)
  鈴木幸子,高木夕希,坂根寛人,橋本恵梨華,垣原美紗樹,服部有那,大平晃也,所真昼,田村彰吾,高木明,鈴木敦夫,鈴木伸明,松下正,山崎鶴夫,小嶋哲人
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] 血漿検体測定を目指したアンチトロンビン抵抗性凝固第X因子検出法の構築2018
- Author(s)
  田村彰吾、高木明、藤岡亮也、服部有那、垣原美紗樹、鈴木幸子、高木夕希、小嶋哲人
- Organizer
  第19回日本検査血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] Many of the prothrombin mutations in the sodium-binding region cause an antithrombin- resistance phenotype2018
- Author(s)
  Shogo Tamura, Moe Murata-Kawakami, Yuki Takagi, Sachiko Suzuki, Akira Katsumi, Akira Takagi, Tetsuhito Kojima
- Organizer
  第40回日本血栓止血学会学術集会学術推進委員会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] 鈴木敦夫、鈴木伸明、兼松毅、岸本磨由子、田村彰吾、高木明、川上萌、梶浦容子、小嶋哲人、松下正2018
- Author(s)
  鈴木敦夫、鈴木伸明、兼松毅、岸本磨由子、田村彰吾、高木明、川上萌、梶浦容子、小嶋哲人、松下正
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] 血友病Aにおいて関節症の進行抑制には出血抑制よりも高い FVIII活性が必要である2018
- Author(s)
  鈴木伸明、鈴木敦夫、高橋伸典、田村彰吾、兼松毅、高木明、小嶋俊久、清井仁、小嶋哲人、石黒直樹、松下正
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] Peri-arteriolar megakaryopoietic microenvironment via reciprocal CLEC-2/PDPN axis in mouse bone marrow2018
- Author(s)
  Shogo Tamura, Katsue Suzuki-Inoue, Yukio Ozaki, Tetsuhito Kojima
- Organizer
  第80回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] 脳梗塞を発症したフィブリノケゲン異常症の分子病態機能解析2018
- Author(s)
  服部有那,垣原美紗樹,高木夕希,鈴木幸子,橋本恵梨華,坂根寛人,大平晃也,所真昼,田村彰吾,高木明,鈴木伸明,松下正,小嶋哲人
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Haploid origin of unusual Inv22 X-chromosome carrying wild-type telomere region in severe hemophilia A patients2018
- Author(s)
  Misaki Kakihara, Shogo Tamura, Yuna Hattori, Sachiko Suzuki, Koya Odaira, Mahiru Tokoro, Takeshi Kanematsu, Nobuaki Suzuki, Tadashi Matsushita, Tetsuhito Kojima
- Organizer
  APSTH2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] 脳梗塞を発症したフィブリノゲン異常症の分子病態機能解析2018
- Author(s)
  服部有那、垣原美紗樹、高木夕希、鈴木幸子、橋本恵梨華、坂根寛人、田村彰吾、高木明、松下正、小嶋哲人
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] F8 Inv22を含む複雑な変異を同定した重症血友病A症例の遺伝学的変異アレル由来の検索2018
- Author(s)
  垣原美紗樹、田村彰吾、服部有那、高木夕希、鈴木幸子、橋本恵梨華、坂根寛人、大平晃也、所真昼、高木明、小川実加、兼松毅、鈴木伸明、松下正、小嶋哲人
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] Functional analysis of a variant fibrinogen from dysfibrinogenemia patient with cerebral2018
- Author(s)
  Yuna Hattori, Takagi Yuki, Misaki Kakihara, Sachiko Suzuki, Koya Odaira, Mahiru Tokoro, Shogo Tamura, Tsuyoshi Kanemetsu, Nobuaki Suzuki, Tadashi Matsushita, Tetsuhito Kojima
- Organizer
  The 10th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] アンチトロンビン抵抗性の診断 -検査法を中心に-2018
- Author(s)
  高木明、田村彰吾、小嶋哲人
- Organizer
  第19回日本検査血液学会学術集会シンポジウム1 特発性血栓症
- Invited
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] 血液凝固第V因子欠乏症を合併する血友病A症例：第２報・凝血学的評価2018
- Author(s)
  鈴木幸子、髙木夕希、坂根寛人、橋本恵梨華、垣原美紗樹、服部有那、大平晃也、所真昼、田村彰吾、高木明、鈴木敦夫、鈴木伸明、松下正、山崎鶴夫、小嶋哲人
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19910
[Presentation] Antithrombin resistance: a unique inherited thrombophilia2018
- Author(s)
  Tetsuhito Kojima
- Organizer
  The 10th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] 血漿検体測定を目指したアンチトロンビン抵抗性凝固第X因子検出法の構築2018
- Author(s)
  田村彰吾,高木明,藤岡亮也,服部有那,垣原美紗樹,高木夕希,鈴木幸子,高木夕希,小嶋哲人
- Organizer
  第19回日本検査血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] F8 Inv22を含む複雑な変異を同定した重症血友病A症例の遺伝学的変異アレル由来の検索2018
- Author(s)
  垣原美紗樹,田村彰吾,服部有那,高木夕希,鈴木幸子,橋本恵梨華,坂根寛人,大平晃也,所真昼,高木明,小川実加,兼松毅,鈴木伸明,松下正,小嶋哲人
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Antithrombin resisitance 検査法の改良：Bovine FXa/Va prothrombin activator システムの構築と血液凝固分析装置適応条件の検討2018
- Author(s)
  田村彰吾，川上萌，垣原美紗樹，服部有那，鈴木幸子，高木夕希，高木明，小嶋哲人
- Organizer
  第12 回日本血栓止血学会学術標準化委員会（SSC）シンポジウム
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] Peri-arteriolar megakaryopoieticmicroenviroment via reciprocal CLEC-2/PDPN axis mouse bone marrow2018
- Author(s)
  Shogo Tamura, Katsue Suzuki-Inoue, Yukio Ozaki, Tetsuhito Kojima
- Organizer
  第80回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Haploid origin of unusual Inv22 X-chromosome carrying wild-type telomere region in severe hemophilia A patients2018
- Author(s)
  Misaki Kakihara, Shogo Tamura, Yuna Hattori, Sachiko Suzuki, Koya Odaira, Mahiru Tokoro, Takeshi Kanematsu, Nobuaki Suzuki, Tadashi Matsushita, Tetsuhito Kojima
- Organizer
  The 10th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] 特発生血栓 : アンチトロンビン抵抗性の診断－凝検査法を中心に－2018
- Author(s)
  高木明,田村彰吾,小嶋哲人
- Organizer
  第19回日本検査血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] スプライシング異常を引き起こす血液凝固第IX遺伝子サイレント変異・血友病B分子病態2018
- Author(s)
  大平晃也,田村彰吾,坂根寛人,所真昼,垣原美紗樹,服部有那,橋本恵梨華,鈴木幸子,高木夕希,高木明,兼松毅,岸本麻由子,鈴木伸明,松下正,小嶋哲人
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Compound heterozygosity for mutations in ITGA2B including a novel p.Cys198Ser in Glanzmann Thrombasthenia2017
- Author(s)
  Erika Hashimoto, Shinji Kunishima, Yuki Takagi, Sachiko Suzuki, Ayumi Makiyama, Hiroto Sakane, Akiya Fujioka, Takahiro Uehara, Shogo Tamura, Akira Takagi, Tetsuhito kojima
- Organizer
  XXVI Congress of International Society on Thrombosis and Haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] アンチトロンビン抵抗性凝固第 Xa 因子検出法の開発2017
- Author(s)
  藤岡亮也、中田悠紀子、坂根寛人、橋本恵梨華、河村奈美、槇山愛弓、鈴木幸子、高木夕希、田村彰吾、高木明、小嶋哲人
- Organizer
  第39回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] Assessment of F9 mutation associated with inhibitor development in Japanese hemophilia B patients2017
- Author(s)
  Hiroto Sakane, Shogo Tamura, Erika Hashimoto, Akiya Fujioka, Ayumi Makiyama, Nami Kawamura, Sachiko Suzuki, Yuki Takagi, Tsuyoshi Kanematsu, Mayuko Kishimoto, Mika Ogawa, Nobuaki Suzuki, Tadashi Matsushita, Hiroshi Yada, Midori Shima, Tetsuhito Kojima
- Organizer
  XXVI Congress of International Society on Thrombosis and Haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] 新しい遺伝性血栓性素因：アンチトロンビン・レジスタンス2017
- Author(s)
  小嶋哲人
- Organizer
  第59回日本小児血液・がん学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Thrombin generation assay CANNOT identify antithrombin resistance during anticoagulant therapy2017
- Author(s)
  Yuki Takagi, Sachiko Suzuki, Nami Kawamura, Ayumi Makiyama, Hiroto Sakane, Erika Hashimoto, Akiya Fujioka, Shogo Tamura, Akira Takagi, Valentina Djordjevic, Tetsuhito Kojima
- Organizer
  XXVI Congress of International Society on Thrombosis and Haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] アンチトロンビン抵抗性はトロンビン生成試験(TGA)により検出可能か2017
- Author(s)
  高木夕希、鈴木幸子、河村奈美、槇山愛弓、坂根寛人、橋本恵梨華、藤岡亮也、田村彰吾、高木明、小嶋哲人
- Organizer
  第39回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] Unusual Genomic Rearrangement combined with Inv22 and wild-type X-chromosome in severe hemophilia A patients2017
- Author(s)
  Shogo Tamura, Misaki Kakihara, Yuna Hattori, Erika Hashimoto, Hiroto Sakane, Yuki Takagi, Mika Ogawa, Takeshi Kanematsu, Nobuaki Suzuki, Akira Takagi, Tadashi Matsushita, Tetsuhito kojima
- Organizer
  XXVI Congress of International Society on Thrombosis and Haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Thrombin generation assay CANNOT identify antithrombin resistance during anticoagulant therapy2017
- Author(s)
  Yuki Takagi, Sachiko Suzuki, Nami Kawamura Ayumi Makiyama, Hiroto Sakane, Erika Hashimoto, Akiya Fujioka, Shogo Tamura, Akira Takagi, Tetsuhito Kojima
- Organizer
  XXVI Congress of International Society on Thrombosis and Haemostasis,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] Molecular basis of F8 gene abnormality in hemophilia A patients in Nagoya2016
- Author(s)
  Nami KAWAMURA, Ayumi MAKIYAMA, Yuki TAKAGI, Erika HASHIMOTO, Hiroto SAKANE, Akiya FUJIOKA, Shogo TAMURA, Akira TAKAGI, Nobuaki SUZUKI, Tadashi MATSUSHITA, Tetsuhito KOJIMA
- Organizer
  The 9th Congress of Asia Pacific Society of Thrombosis and Hemostasis (APSTH)
- Place of Presentation
  Taipei
- Year and Date
  2016-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] プロテインC欠乏症51家系のPROC遺伝子解析2016
- Author(s)
  槇山愛弓、高木夕希、河村奈美、橋本恵梨華、田村彰吾、高木明、岸本磨由子、鈴木伸明、松下正、小嶋哲人
- Organizer
  第17回日本検査血液検査血液学会学術集会
- Place of Presentation
  博多
- Year and Date
  2016-08-06
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] プロトロンビンArg596ミスセンス変異がトロンビンのトロンボモジュリン結合能に及ぼす影響2016
- Author(s)
  高木夕希, 河村奈美, 槇山愛弓, 橋本恵梨華, 田村彰吾, 高木明, 小嶋哲人
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] Prothrombin missense mutations at 596Arg reduced the affinity of mutant thrombin to thrombomodulin controlled by Na+ concentration.2016
- Author(s)
  Yuki Takagi, Nami Kawamura, Ayumi Makiyama, Erika Hashimoto, Shogo Tamura, Akira Takagi, Tetsuhito Kojima
- Organizer
  XXIX International Symposium on Technical Innovations in Laboratory Hematology (ISLH)
- Place of Presentation
  Milano, Italy
- Year and Date
  2016-05-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] A NOVEL LARGE DELETION FOUND IN A JAPANESE FAMILY WITH ANTITHROMBIN DEFICIENCY2016
- Author(s)
  Erika HASHIMOTO, Yuki TAKAGI, Nami KAWAMURA, Ayumi MAKIYAMA, Hiroto SAKANE, Akiya FUJIOKA, Shogo TAMURA, Akira TAKAGI, Yoshifumi FUKUSHIMA, Makoto KANEKO, Tetsuhito KOJIMA
- Organizer
  The 9th Congress of Asia Pacific Society of Thrombosis and Hemostasis (APSTH)
- Place of Presentation
  Taipei
- Year and Date
  2016-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Prothrombin missense mutations at 596Arg reduced the affinity of mutant thrombin to thrombomodulin controlled by Na+ concentration2016
- Author(s)
  Yuki Takagi, Nami Kawamura, Ayumi Makiyama, Erika Hashimoto, Shogo Tamura, Akira Takagi, Tetsuhito Kojima
- Organizer
  XXIX International Symposium on Technical Innovations in Laboratory Hematology
- Place of Presentation
  Milano
- Year and Date
  2016-05-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08967
[Presentation] 低フィブリノゲン血症3症例の遺伝子解析2016
- Author(s)
  高木夕希、河村奈美、槇山愛弓、橋本恵梨華、安藤裕実、加藤衣央、田村彰吾、高木明、小嶋哲人
- Organizer
  第38回日本血栓止血学会学術集会
- Place of Presentation
  奈良
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-16K09825
[Presentation] Analysis of prothrombin mutants in NA+ binding domain as a potential candidate conveying antithrombin resistance2015
- Author(s)
  Moe Murata, Naoki Mizutani, Yuki Takagi, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Tetsuhito Kojima
- Organizer
  XXV Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] アンチトロンビン抵抗性検出検査法の自動凝固検査機器への最適化 Part 22015
- Author(s)
  村田　萌、水谷直貴、高木夕希、長谷部瞭、小塚敏弘、中田悠紀子、高木　明、松下　正、小嶋哲人
- Organizer
  第16回日本検査血液検査血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] ロトロンビン変異による新たなアンチトロンビン抵抗性変異の候補解析2015
- Author(s)
  村田萌、水谷直貴、高木夕希、長谷部瞭、小塚敏弘、中田悠紀子、槇山愛弓、河村奈美、橋本恵梨華、高木明、松下正、小嶋哲人
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] 深部静脈血栓症で発症しアンチトロンビン抵抗性を示した本邦初 Prothrombin Belgrade 変異の一家系2015
- Author(s)
  岸本磨由子、鈴木伸明、村田萌、小川実加、兼松毅、高木明、小嶋哲人、松下正
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] A case of severe hemophilia B associated with a large insertion of SVA RETROTRANSPOSON in the coagulation factor IX gene.2015
- Author(s)
  Naoki Mizutani, Yuki Nakamura, Moe Murata, Yuki Takagi, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Jun-ichi Kitazawa, Midori Shima, Tetsuhito Kojima
- Organizer
  XXV Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-06-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] Analysis of prothrombin missense mutants at 596ARG by single nucleotide substitution for anticoagulant system.2015
- Author(s)
  Yuki Takagi, Moe Murata, Yuki Nakamura, Toshihiro Kozuka, Yukiko Nakata, Ryo Hasebe, Akira Takagi, Tetsuhito Kojima
- Organizer
  XXV Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-06-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] 深部静脈血栓症で発症したアンチトロンビンレジスタンス症例の抗凝固療法2015
- Author(s)
  岸本磨由子、鈴木伸明、村田萌、小川実加、兼松毅、高木明、小嶋哲人、松下正
- Organizer
  第16回日本検査血液検査血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] 深部静脈血栓症で発症したアンチトロンビンレジスタンス症例の抗凝固療法2015
- Author(s)
  岸本磨由子、鈴木伸明、村田　萌、小川実加、兼松　毅、高木　明、小嶋哲人、松下　正
- Organizer
  第16回日本検査血液検査血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] Practical laboratory assay to detect abnormal prothrombin conveying thrombomodulin resistance2015
- Author(s)
  高木夕希、水谷直貴、村田萌、小塚敏弘、中田悠紀子、長谷部瞭、河村奈美、槇山愛弓、橋本恵梨華、高木明、小嶋哲人高木夕希、水谷直貴、村田萌、小塚敏弘、中田悠紀子、長谷部瞭、河村奈美、槇山愛弓、橋本恵梨華、高木明、小嶋哲人
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] 新たな血栓性素因：アンチトロンビン･レジスタンス2015
- Author(s)
  小嶋哲人
- Organizer
  第25回日本産婦人科新生児血液学会
- Place of Presentation
  東京
- Year and Date
  2015-06-05
- Invited
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] アンチトロンビン抵抗性検出検査法の自動凝固検査機器への最適化 Part 22015
- Author(s)
  村田萌、水谷直貴、高木夕希、長谷部瞭、小塚敏弘、中田悠紀子、高木明、松下正、小嶋哲人
- Organizer
  第16回日本検査血液検査血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] 先天性アンチトロンビン欠乏症８症例SERPINC1遺伝子解析2015
- Author(s)
  中田悠紀子、小塚敏弘、長谷部瞭、高木夕希、村田萌、上牧務、松尾真稔、高木明、松下正、小嶋哲人
- Organizer
  第16回日本検査血液検査血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] Analysis of prothrombin mutants in NA+ binding domain as a potential candidate conveying antithrombin resistance.2015
- Author(s)
  Moe Murata, Naoki Mizutani, Yuki Takagi, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Tetsuhito Kojima
- Organizer
  XXV Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-06-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] A congenital dysprothrombinemia with both decreased prothrombin activity and antithrombin resistance2015
- Author(s)
  高田麻央、森下英里子、谷口文苗、關口暁子、小林英里奈、朝倉英策、高木明、小嶋哲人、大竹茂樹
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] プロトロンビンArg596 における一塩基置換ミスセンス変異体のトロンボモジュリン抵抗性評価2015
- Author(s)
  高木夕希、村田萌、中村友紀、小塚敏弘、中田悠紀子、長谷部瞭、橋本恵梨華、高木明、小嶋哲人
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] Analysis of prothrombin missense mutants at 596ARG by single nucleotide substitution for anticoagulant system2015
- Author(s)
  Yuki Takagi, Moe Murata, Yuki Nakamura, Toshihiro Kozuka, Yukiko Nakata, Ryo Hasebe, Akira Takagi, Tetsuhito Kojima
- Organizer
  XXV Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] 深部静脈血栓症で発症しアンチトロンビン抵抗性を示した本邦初 Prothrombin Belgrade 変異の一家系2015
- Author(s)
  岸本磨由子、鈴木伸明、村田萌、小川実加、兼松毅、高木明、小嶋哲人、松下正
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] Practical laboratory assay to detect abnormal prothrombin conveying thrombomodulin resistance.2015
- Author(s)
  高木夕希、水谷直貴、村田萌、小塚敏弘、中田悠紀子、長谷部瞭、河村奈美、槇山愛弓、橋本恵梨華、高木明、小嶋哲人
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] Investigation of molecular mechanisms of PS mRNA up-regulation by progestin isoforms in HepG2 cells.2015
- Author(s)
  小塚敏弘、長谷部瞭、中田悠紀子、槇山愛弓、河村奈美、中村友紀、高木夕希、村田萌、水谷直貴、高木明、小嶋哲人
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] Antidotes to dabigatran and anti-Xa anticoagulants2015
- Author(s)
  小嶋哲人
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] プロトロンビン変異による新たなアンチトロンビン抵抗性変異の候補解析2015
- Author(s)
  村田　萌、水谷直貴、高木夕希、長谷部瞭、小塚敏弘、中田悠紀子、槇山愛弓、河村奈美、橋本恵梨華、高木　明、松下　正、小嶋哲人
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] プロトロンビン Arg596 における一塩基置換ミスセンス変異体のトロンボモジュリン抵抗性評価2015
- Author(s)
  高木夕希、村田　萌、中村友紀、小塚敏弘、中田悠紀子、長谷部瞭、橋本恵梨華、高木　明、小嶋哲人
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] 先天性アンチトロンビン欠乏症８症例SERPINC1遺伝子解析2015
- Author(s)
  中田悠紀子、小塚敏弘、長谷部瞭、高木夕希、村田　萌、上牧　務、松尾真稔、高木　明、松下　正、小嶋哲人
- Organizer
  第16回日本検査血液検査血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] 血小板無力症に同定された GPIIb 遺伝子のミスセンス変異とスプライス変異の複合ヘテロ変異解析2015
- Author(s)
  橋本恵梨華、村田萌、槇山愛弓、河村奈美、小塚敏弘、中田悠紀子、長谷部瞭、高木夕希、水谷直貴、高木明、國島伸治、松下正、小嶋哲人
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] 原因不明であった静脈血栓塞栓症にみられたアンチトロンビン抵抗性を示す本邦２家系目のプロトロンビン異常症2014
- Author(s)
  村田　萌、高木夕希、中村友紀、長谷部　瞭、小塚敏弘、中田　悠紀子、高木　明、村手　隆、松下　正、小嶋哲人
- Organizer
  第33回日本臨床検査医学会東海・北陸支部例会
- Place of Presentation
  名古屋大学鶴舞キャンパス
- Year and Date
  2014-08-02
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] アンチトロンビン抵抗性の関与が疑われた家族性再発性肺血栓塞栓症の1例2014
- Author(s)
  吉田　律、角田　聖子、長谷川　潤、大木　理次、武本　知之、小山　達也、山崎　弘二、関　晋吾、吉村　道博、高木　明、小嶋　哲人
- Organizer
  第233回日本循環器学会関東・甲信越地方会
- Place of Presentation
  東京
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] 原因不明であった静脈血栓塞栓症にみられたアンチトロンビン抵抗性を示す本邦２家系目のプロトロンビン異常症2014
- Author(s)
  村田　萌、高木　明、岸本磨由子、清井　仁、松下　正、小嶋哲人
- Organizer
  第33回日本臨床検査医学会東海・北陸支部例会
- Place of Presentation
  名古屋
- Year and Date
  2014-08-02
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] Regulatory mechanism of SPHK2 expresssion in colon cancer cell lines2013
- Author(s)
  Mizutani N, Inoue M, Nishida Y, Omori Y, Suzuki M, Koizumi K, Takagi A, Kojima T, Iwaki S, Fujii S, Nakamura M, Banno Y, Nozawa Y, Murate T
- Organizer
  7^<th> International Conference of Ceramide
- Place of Presentation
  Montauk, NY. USA
- Year and Date
  2013-10-21
- Data Source
  KAKENHI-PROJECT-23590667
[Presentation] Genetic risk factors for thrombophilia in Japanese2013
- Author(s)
  Tetsuhito Kojima
- Organizer
  Annual Meeting of Korean Society on Thrombosis and Haemostasis
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] The mechanism of cytotoxicity by resveratrol against human leukemia cell lines2013
- Author(s)
  Omori Y, Mizutani N, Inoue M, Nishida Y, Suzuki M, Koizumi K, Takagi A, Kojima T, Iwaki S, Fujii S, Nakamura M, Nozawa Y, Murate T
- Organizer
  7^<th> International Conference of Ceramide
- Place of Presentation
  Montauk, NY. USA
- Year and Date
  2013-10-22
- Data Source
  KAKENHI-PROJECT-23590667
[Presentation] Effects of prothrombin Yukuhashi mutation on thrombomodulin-protein C system2013
- Author(s)
  TAKAGI Yuki, KAT O Io, ANDO Yumi, MURATA Moea, SUZUKI Atsuo, TAKAGI Akira, MATSUSHITA Tadashi, SAITO Hidehiko, KOJIMA Tetsuhito
- Organizer
  XXIV Congress of International Society on Thrombosis and Haemostasis,
- Place of Presentation
  Amsterdam, The Neterlands
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] A clinical laboratory test detecting antithrombin resistance of the new thrombophilia2013
- Author(s)
  MURATA Moea, TAKAGI Akira, SUZUKI Atsuo,TAKAGI Yuki, KATO Io, ANDO Yumi, MURATE Takashi, MATSUSHITA Tadashi, SAITO Hidehiko, KOJIMA Tetsuhito
- Organizer
  XXIV Congress of International Society on Thrombosis and Haemostasis,
- Place of Presentation
  Amsterdam, The Neterlands
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] A novel mechanism of hereditary thrombosis by antithrombin resistance.2013
- Author(s)
  Tetsuhito Kojima
- Organizer
  XXIV Congress of nternational Society on Thrombosis and Haemostasis
- Place of Presentation
  Amsterdam, The Neterlands
- Invited
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] アンチトロンビン抵抗性解析法の改良と評価2013
- Author(s)
  村田　萌、高木　明、中村友紀、加藤衣央、安藤裕実、高木夕希、村手　隆、松下　正、小嶋哲人
- Organizer
  第14回日本検査血液検査血液学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] プロトロンビンYukuhashi由来変異型トロンビンのトロンボモジュリン・プロテインC系に及ぼす影響2013
- Author(s)
  高木夕希、高木　明、鈴木敦夫、奥山恵理子、村田　萌、加藤衣央、安藤裕実、中村友紀、松下　正、齋藤英彦、小嶋哲人
- Organizer
  第14回日本検査血液検査血液学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] Molecular mechanisms of syndecan-4 upregulation by TNF-. in the endothelial-like EAhy926 cells2012
- Author(s)
  Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Miyawaki Y, Suzuki A, Takagi A, Murate T, Saito T, Kojima T
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] A Possible Mechanism for Inv22-related F8 Large Deletions in Severe Hemophilia A Patients with High Responding Factor VIII Inhibitors2012
- Author(s)
  Fujita J, Miyawaki Y, Suzuki A, Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Hosaka M, Takagi A, Murate T, Kajiura Y, Suzuki N, Matsushita T, Saito T, Kojima T
- Organizer
  VIIth Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] NF-kappaB is essential for Syndecan-4 up-regulation by TNF-alpha in Vascular Endothelial-like EAhy926 Cells2012
- Author(s)
  Okuyama E, Murata M, Suzuki A, Miyawaki Y, Ando Y, Kato I, Takagi Y, Takagi A, Murate T, Saito T, Kojima T
- Organizer
  VIIth Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] Immunosuppressant IMP dehydrogenase inhibitors up-regulated coagulation factor VII mRNA2012
- Author(s)
  Suzuki A, Miyawaki Y, Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Takagi A, Murate T, Saito T, Kojima T
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] A Possible Mechanism for Inv22-related F8 Large Deletions in Severe Hemophilia A Patients with High Responding Factor VIII Inhibitors.2012
- Author(s)
  Fujita J, Miyawaki Y, Suzuki A, Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Hosaka M, Takagi A, Murate T, Kajiura Y, Suzuki N, Matsushita T, Saito H, Kojima T
- Organizer
  VIIth Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Place of Presentation
  Meibourun, Australia
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] 静脈血栓塞栓症リスク・アンチトロンビン抵抗性とそのスクリーニング検査2012
- Author(s)
  高木明、宮脇由理、鈴木敦夫、藤田絢子、牧明日加、奥山恵理子、村田萌、村手隆、松下正、小嶋哲人
- Organizer
  第34回日本血栓止血学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659114
[Presentation] Molecular Basis of Coagulation Factor IX Gene Abnormalities in 16 Japanese Hemophilia B Patients2012
- Author(s)
  Murata M, Okuyama E, Suzuki A, Miyawaki Y, Ando Y, Kato I, Takagi Y, Hosaka M, Takagi A, Murate T, Kishimoto, M, Suzuki N, Matsushita T, Saito T, Kojima T
- Organizer
  VIIth Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] Up-regulation mechanisms of syndecan-4, a heparan sulfate proteoglycan, expression by TNF-a in human endothelial like EAhy926 cells2012
- Author(s)
  Okuyama E, Murata M, Suzuki A, Ando Y, Kato I, Takagi Y, Takagi A, Murate T, Saito T, Kojima T
- Organizer
  第35回日本分子生物学会年
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] 血栓性素因の病因と病態2011
- Author(s)
  小嶋哲人
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場(招待講演)
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] A novel prothrombin gene mutation leads to an at-resistant thrombin in afamily with inherited thrombophilia2011
- Author(s)
  Miyawaki Y, Suzuki A, Fujimori Y, Fujita J, Maki A, Takagi A, Murate T, Sakata M, Okamoto K, Matsushita T, Kojima T
- Organizer
  XXIIIth CONGRESS OF THE INTERNATIONAL SOCIETY ON THROMBOSIS AND HAEMOSTASIS
- Place of Presentation
  KYOTO
- Data Source
  KAKENHI-PROJECT-22659114
[Presentation] OS-3-120: Molecular basis of an AT-resistant variant thrombin found in a Japanese family with thrombophilia2011
- Author(s)
  Miyawaki Y, Suzuki A, Fujita J, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Kunishima S, Sakai M, Okamoto K, Matsushita T, Kojima T
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] アンチトロンビン抵抗性解析法とその評価2011
- Author(s)
  高木明、宮脇由理、鈴木敦夫、藤田絢子、牧明日加、奥山恵理子、村田萌、村手隆、松下正、小嶋哲人
- Organizer
  第58回日本臨床検査医学会学術集
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22659114
[Presentation] A NOVEL PROTHROMBIN GENE MUTATION LEADS TO AN AT-RESISTANT THROMBIN IN A FAMILY WITH INHERITED THROMBOPHILIA2011
- Author(s)
  Miyawaki Y, Suzuki A, Fujimori Y, Fujita J, Maki A, Takagi A, Murate T, Sakai M, Okamoto K, Matsushita T, Kojima T
- Organizer
  XXIIIrd Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] 教育講演:基本シリーズ:血栓・止血血栓性素因の病因と病態2011
- Author(s)
  小嶋哲人
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] Historical perspective and future direction of coagulation research2011
- Author(s)
  H Saito, T Matsushita, T Kojima
- Organizer
  XXIIIrd Congress of ISTH
- Place of Presentation
  京都国際会議場(招待講演)
- Year and Date
  2011-07-27
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] DISTINCT X-CHROMOSOMAL REARRANGEMENTS WITH F8-INTRON22 INVERSION IN THREE UNRELATED JAPANESE SEVERE HEMOPHILIA A PATIENTS WITH HIGH TITER INHIBITOR2011
- Author(s)
  Fujita J, Suzuki A, Miyawaki Y, Maki A, Fujimori Y, Takagi A, Murate T, Matsushita T, Suzuki N, Saito H, Kojima T
- Organizer
  XXIIIrd Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] PS-1-72: Unusual X-chromosomal rearrangements with F8-int22 inversion in three severe hemophilia A patients2011
- Author(s)
  Fujita J, Miyawaki Y, Suzuki A, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Matsushita T, Suzuki N, Saito H, Kojima T
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] PS-1-63: Thrombophilia and JAK2 V617F mutations in Japanese patients with Budd-Chiari syndrome2011
- Author(s)
  Maki A, Fujita J, Okuyama E, Murata M, Miyawaki Y, Suzuki A, Takagi A, Murate T, Kojima T
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] アンチトロンビン抵抗性を検出するトロンビン不活化動態解析法の開発2011
- Author(s)
  高木明、宮脇由理、鈴木敦夫、藤田絢子、牧明日加、奥山恵理子、村田萌、村手隆、松下正、小嶋哲人
- Organizer
  12回日本検査血液学会学術集会
- Place of Presentation
  倉敷
- Data Source
  KAKENHI-PROJECT-22659114
[Presentation] Historical perspective and future direction of coagulation research2011
- Author(s)
  Saito H, Matsushita T, Kojima T
- Organizer
  XXIIIrd Congress of International Society on Thrombosis and Haemostasis
- Place of Presentation
  XXIIIrd Congress of International Society on Thrombosis and Haemostasis
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] A survey of venous thromboembolism in Japanese patients with inherited anticoagulant deficiency2010
- Author(s)
  K Yokoyama, T Kojima, Y Sakata, T Kawasaki, H Tsuji, T Miyata, S Okamoto, M Murata
- Organizer
  第72回日本血液学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] A novel endoglin gene mutation associated with hereditary hemorrhagic telangiectasia in a Japanese2010
- Author(s)
  A Suzuki, Y Miyawaki, J Fujita, A Maki, Y Fujimori, A Takagi, T Murate, M Teranishi, H Saito, T Kojima
- Organizer
  第72回日本血液学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] Receptor interacting protein 140 (RIP140) mediated ERα-Sp1 and corepressor-HDAC3 complex association in 17β-estradiol dependent down-regulation of protein S2010
- Author(s)
  A Suzuki, Y Miyawaki, J Fujita, A Maki, Y Fujimori, A Takagi, T Murate, H Saito, T Kojima
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] Genetic Disorders Related to Coagulopathy Prevalent in the Far East2010
- Author(s)
  T Kojima
- Organizer
  6th Congress of the Asia Pacific Society on Thrombosis and Haemostasis (APSTH Bali 2010)
- Place of Presentation
  Bali
- Data Source
  KAKENHI-PROJECT-22590524
[Presentation] 新規Gr cm pI 変異L1503R のv cm Wi11ebrand病type2A発症における役割2008
- Author(s)
  平島寛司、柏木隆宏、松下正、伊藤康友、高木明、村手隆、勝見章、直江知樹、小嶋哲人
- Organizer
  第31回日本血栓止血学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 第VIII因子遺伝子のイントロン22逆位解析法-DNAポリメラーゼの比較-2008
- Author(s)
  藤森祐多、山田貴之、奥村薫、田中亮子、中島大輔、鈴木敦夫、宮脇由理、高木明、村手隆、小嶋哲人
- Organizer
  第9回日本検査血液学会学術集会
- Place of Presentation
  津
- Year and Date
  2008-07-26
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] Regulatory mechanism of neutral sphingomyelinase 2 gene expression by daJnorubicin in MCF-7 cells2008
- Author(s)
  H Ito, M Murakami, S Gao, A Furuhata, K Yoshida, Y Tagawa, S Sobue, A Takagi, T Kojima, M Suzuki, Y Banno, Y Nozawa, K Koizumi, T Murate
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 日本人の血栓症の遺伝的著景に関する調査研究2008
- Author(s)
  宮田敏行, 小嶋哲人, ほか
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 女性血友病Aの分子病態解析2008
- Author(s)
  宮脇由理、鈴木敦夫、田中亮子、中島大輔、藤森祐多、山田貴之、奥村薫、高木明、村手隆、松下正、高松純樹、小嶋哲人
- Organizer
  第31回日本血栓止血学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] GATA-1, GATA-2 によるWT1発現調節の解析2008
- Author(s)
  古畑彩子、村上真史、高四強、木村有美、伊藤裕美、高木明、小嶋哲人、安部明弘、直江知樹、村手隆
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 日本人における血栓性素因遺伝子変異データベースの作成2008
- Author(s)
  藤森祐多, 小嶋哲人, ほか
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] ATRA inhibits ceramide kinase transcription through an ATRA-related transcription factor, COU~-TF1, in a human neuroblastoma cell line, SH-SY5Y cells2008
- Author(s)
  M Murakami, H Ito, S Gao, A Furuhata, K Yoshida, Y Tagawa, S Sobue, A Takagi, T Kojima, M Suzuki, Y Banno, Y Nozawa, T Murate
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] v-SrcによるSPHKl mRNA安定化と発現増強2008
- Author(s)
  祖父江沙矢加、村上真史、坂野喜子、伊藤裕美、高四強、古畑彩子、高木明、小嶋哲人、野澤義則、村手隆、市原正智
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 日本人の血栓症の遺伝的背景に関する調査研究2008
- Author(s)
  宮田敏行、川崎富夫、辻肇、窓岩清治、坂田洋一、小嶋哲人、村田満、阪田敏幸、竹下聡、小久保喜弘、小亀浩一、岡田裕美、池田康夫
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 先天性凝固第VII 因子欠損症の分子病態解析2008
- Author(s)
  田中亮子、中島大輔、鈴木敦夫、宮脇由理、藤森祐多、山田貴之、奥村薫、勝見章、山本晃士、松下正、高松純樹、高木明、村手隆、小嶋哲人
- Organizer
  第31回日本血栓止血学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 日本人における血栓性素因遺伝子変異データベースの作成2008
- Author(s)
  藤森祐多、奥村薫、山田貴之、田中亮子、中島大輔、鈴木敦夫、宮脇由理、村手隆、高木明、小嶋哲人
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 女性血友病Aの1例2008
- Author(s)
  宮脇由理、鈴木敦夫、田中亮子、中島大輔、藤森祐多、山田貴之、奥村薫、高木明、村手隆、松下正、高松純樹、小嶋哲人
- Organizer
  第9回愛知県医学検査学会
- Place of Presentation
  豊橋
- Year and Date
  2008-05-25
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] シンポジウム2「血栓性素因の病態と診断の進歩」 : 血栓性素因のとしてのATとPC異常2008
- Author(s)
  小嶋哲人
- Organizer
  第9回日本検査血液学会学術集会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-07-26
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 新規Group I 変異L1503R のvonWillebrand 病type 2A発症における役割2008
- Author(s)
  柏木隆宏、松下正、伊藤康友、高木明、村手隆、勝見章、平島寛司、直江知樹、小嶋哲人
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 「抗血栓薬の最近の進歩」関連学会ジョイントシンポジウム2008
- Author(s)
  小嶋哲人
- Organizer
  日本循環器学会第31回日本血栓止血学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] Mutated Ras-induced. Phospholipase D1 transcripton in a human colon adenocarcinoma celt line, DLD-12008
- Author(s)
  S Gao, M Murakami, H Ito, A Furuhata, K Yoshida, Y Tagawa, S Sobue, A Takagi, T Kojima, Y Banno, M Suzuki, Y Nozawa, T Murate
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] シンポジウム2「血栓性素因の病態と診断の進歩」 : 血栓性素因のとしてのAT とPC異常2008
- Author(s)
  小嶋哲人
- Organizer
  第9回日本検査血液学会学術集会
- Place of Presentation
  津
- Year and Date
  2008-07-26
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 先天性プロテインC欠損症7家系における遺伝子解析2007
- Author(s)
  田中亮子、中島大輔、柏木隆宏、三田直美、藤森祐多、山田貴之、奥村薫、勝見章、松下正、山本晃士、高松純樹、高木明、村手隆、小嶋哲人
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  志摩
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] X染色体の不活性化を伴う女児血友病Bの分子病態解析2007
- Author(s)
  奥村薫、山田貴之、柏木隆宏、三田直美、藤森祐多、田中亮子、中島大輔、松下正、小関道夫、高木明、村手隆、小嶋哲人
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  志摩
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] JAK2V617F変異がもたらすBcl-XL発現増加とその転写調節機序の解明2007
- Author(s)
  木村有美、伊藤裕美、祖父江沙矢加、村上真史、根本聡、高四強、古畑彩子、高木明、小嶋哲人、幣光太郎、村手隆
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] The protein S thrombin sensitive region contributes regulation of warfarin treated des-γ-carboxylated protein S secretion: a study of a novel splice site mutation of protein S gene and its molecular consequences2007
- Author(s)
  H. Okada, S. Kunishima, M. Hamaguchi, A. Takagi, K. Yamamoto, J. Takamatsu, T. Matsushita, H. Saito, T. Kojima, T. Yamazak
- Organizer
  XXIInd Congress of ISTH
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2007-07-19
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 60歳時からの鼻出血で発症した遺伝性出血性末梢血管拡張症の遺伝子解析2007
- Author(s)
  中島大輔、田中亮子、柏木隆宏、三田直美、藤森祐多、山田貴之、奥村薫、寺西正明、高木明、村手隆、小嶋哲人
- Organizer
  第30回日本血栓止血学会学術集会
- Place of Presentation
  志摩
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] Molecular basis of antithrombin deficiency in four Japanese patients with pregnancy-associated thrombosis : antithrombin gene abnormalities including two novel mutations2007
- Author(s)
  K. Okumura, Y. Fujimori, T. Kashiwagi, N. Sanda, T. Yamada, A. Takagi, T. Murate, T. Iwasaki, A. Katsumi, K. Yamamoto, T. Matsushita, T. Naoe, H. Saito, T. Kojima
- Organizer
  XXIInd Congress of ISTH, Geneva
- Place of Presentation
  Switzerland
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] Molecular basis of antithrombin deficiency in four Japanese patients with Pregnancy-associated thrombosis: antithrombin gene abnormalities inc1uding two novel mutations.2007
- Author(s)
  K. Okumura, T. Kojima, et. al.
- Organizer
  XXIInd Congress of ISTH
- Place of Presentation
  Geneva, Switzerlamd
- Year and Date
  2007-07-09
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] Four nove1 causative mutations identified in the PROS1 gene of Japanes o deeP vein thrombosis patients with protein S deficiency.2007
- Author(s)
  N. Sanda, T. Kojima, et. al.
- Organizer
  XXIInd Congress of ISTH
- Place of Presentation
  Geneva, Switzerlamb
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] One-Third of Japanese patients with deep vein thrombosis carried the genetic mutations in proteins S, C and antithrombin genes: the sub-group study of blood coagulation abnormality the study group of research on measures for intractable diseases in Japan2007
- Author(s)
  J. Ishikawa, Y. Sato, S. Takeshita, K. Kokame, R. Kimura, S. Honda, T. Kawasaki, E. Suehisa, H. Tsuji, S. Madoiwa, Y. Sakata, T. Kojima, M. Murata, Y. Ikeda, T. Miyata
- Organizer
  XXIInd Congress of ISTH
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] アンチトロンビン欠損症と拡張型心筋症の合併家系における分子病態解析2007
- Author(s)
  藤森祐多、沖松秀美、柏木隆宏、三田直美、田中亮子、中島大輔、山田貴之、奥村薫、高木明、村手隆、内田文、野出孝一、小嶋哲人
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] Four novel causative mutations identified in the PROS1 gene of Japanese deep vein thrombosis patients with protein S deficiency2007
- Author(s)
  N. Sanda, Y. Fujimori, T. Kashiwagi, T. Yamada, K. Okumura, A. Takagi, T. Murate, T. Iwasaki, A. Katsumi, K. Yamamoto, T. Matsushita, T. Naoe, H. Saito, T. Kojima
- Organizer
  XXIInd Congress of ISTH
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] PROS1遺伝子プロモーテー領域内の一塩基置換による先天性プロテインS欠損症2007
- Author(s)
  三田直美、柏木隆宏、藤森祐多、田中亮子、中島大輔、山田貴之、奥村薫、高木明、村手隆、小嶋哲人
- Organizer
  第8回日本検査血液学会学術集会
- Place of Presentation
  福井
- Year and Date
  2007-07-22
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] The protein S thrombin sensitive region contributes regulation of warfarin treated des-γ-carboxylated protein S secretion: a study of a novel splice site mutation of protein S gene and its molecular Consequences.2007
- Author(s)
  N. Okada, T. Kojima, et. al.
- Organizer
  XXIInd Congress of IFTH
- Place of Presentation
  Geneva, Seitzerlamd
- Year and Date
  2007-07-09
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] A large deletion of the PROS1 gene in a deep vein thrombosis patient with protein S deficiency2007
- Author(s)
  T. Yin, S. Takeshita, Y. Sato, T. Sakata, Y. Shin, S. Honda, T. Kawasaki, H. Tsuji, S. T. Kojima, Madoiwa, Y. Sakata, M. Murata, Y. Ikeda, T. Miyata
- Organizer
  XXIInd Congress of ISTH
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] 白血病細胞株におけるSPHK1発現と抗癌剤Daunorubicin体制との関連2007
- Author(s)
  祖父江沙矢加、村上真史、根本聡、伊藤裕美、木村有美、高四強、古畑彩子、高木明、小嶋哲人、村手隆
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-19590553
[Presentation] アンチトロンビン抵抗性検出検査法の自動凝固検査機器への最適化
- Author(s)
  村田　萌、高木夕希、中村友紀、長谷部　瞭、小塚敏弘、中田　悠紀子、高木　明、村手　隆、松下　正、小嶋哲人
- Organizer
  第15回日本検査血液検査血液学会学術集会
- Place of Presentation
  仙台
- Year and Date
  2014-07-20 – 2014-07-21
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] Precise genetic abnormalities in four hemophilia B patients with large deletions of X-chromosome including entire F9
- Author(s)
  Yuki Nakamura, Moe Murata, Yuki Takagi, Toshihiro Kozuka, Yukiko Nakata, Ryo Hasebe, Akira Takagi, Tadashi Matsushita, Tetsuhito Kojima
- Organizer
  The 8th Congress of Asia Pacific Society of Thrombosis and Hemostasis (APSTH)
- Place of Presentation
  Hanoi, Vietnam
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] Antithrombin resistance: a new mechanism of inherited thrombophilia
- Author(s)
  小嶋哲人
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-10-31 – 2014-11-02
- Invited
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] Optimization of the antithrombin resistance assay for the automated analyzer
- Author(s)
  Moe Murata, Yuki Takagi, Yuki Nakamura, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Tetsuhito Kojima
- Organizer
  The 8th Congress of Asia Pacific Society of Thrombosis and Hemostasis
- Place of Presentation
  Hanoi
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] Precise genetic abnormalities in four hemophilia B patients with large deletions of X-chromosome including entire F8
- Author(s)
  Yuki Nakamura, Moe Murata, Yuki Takagi, Toshihiro Kozuka, Yukiko Nakata, Ryo Hasebe, Akira Takagi, Tadashi Matsushita, Tetsuhito Kojima
- Organizer
  The 8th Congress of Asia Pacific Society of Thrombosis and Hemostasis
- Place of Presentation
  Hanoi
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25460683
[Presentation] アンチトロンビン抵抗性検出検査法の自動凝固検査機器への最適化
- Author(s)
  村田　萌、高木夕希、中村友紀、長谷部　瞭、小塚敏弘、中田　悠紀子、高木　明、村手　隆、松下　正、小嶋哲人
- Organizer
  第15回日本検査血液検査血液学会学術集会
- Place of Presentation
  仙台国際センター
- Year and Date
  2014-07-20 – 2014-07-21
- Data Source
  KAKENHI-PROJECT-25293129
[Presentation] Optimization of the antithrombin resistance assay for the automated analyzer
- Author(s)
  Moe Murata, Yuki Takagi, Yuki Nakamura, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Tetsuhito Kojima
- Organizer
  The 8th Congress of Asia Pacific Society of Thrombosis and Hemostasis (APSTH)
- Place of Presentation
  Hanoi, Vietnam
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25293129
[]

1. TAKAGI Akira (30135371)

# of Collaborated Projects: 15 results

# of Collaborated Products: 144 results
2. YAKMAMOTO Koji (90362251)

# of Collaborated Projects: 13 results

# of Collaborated Products: 20 results
3. MATSUSHITA Tadashi (30314008)

# of Collaborated Projects: 10 results

# of Collaborated Products: 68 results
4. MURATE Takashi (30239537)

# of Collaborated Projects: 6 results

# of Collaborated Products: 5 results
5. SAITO Hidehiko (20153819)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
6. SUZUKI Motoshi (80236017)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
7. BANNO Yoshiko (50116852)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
8. TUZUKI Shinobu

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
9. TOWATARI Masayuki

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
10. NOZAWA Yoshinori (10021362)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. TAKAMATSU Junnki (80221365)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. KADOMATSU Kenji (80204519)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. TANIMOTO Mitsune (10240805)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. ABE Akihiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. KOIZUMI Keiko (00118027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. HAMAGUCHI Motohiro (30393177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. YAMAZAKI Tomio (00282202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KUNISHIMA Shinji (60373495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. TSUDA Hiroko (30180003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAKAZONO Eri (10343732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. NOGUCHI Kenta (90757494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. MORISHITA Eriko (50251921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KATO Kiyoko (10253527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. HAYASHI Tatsuya (00242959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. OZAKI Yukio (30134539)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. MIYATA Toshiyuki (90183970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. Tamura Shogo (60722626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
28. 濱崎直孝 (00091265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 隈博幸 (40435136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 佐々木知幸 (40739124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. TSUDA Tomohide

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 松岡明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 安部明宏

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. Oh Doyeun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. Lee Lai Heng

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. Bereczky Zsuzsanna

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. Dusse Luci

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. Carvalho Maria

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. TANINO Mishie

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. KATSUMI Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
41. IWAKI Soichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
42. 谷野功典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 藤井聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 中村光浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 菊地利明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 野沢義則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOJIMA Tetsuhito 小嶋 哲人

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Novel mutation search of antithrombin resistance and its pathological analysis research by mouse modelPrincipal Investigator

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Molecular elucidation of antithrombin resistance mechanism and development of thrombophilia model mouse.Principal Investigator

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Gene analysis of a novel thrombotic risk factor; antithrombin-resistance.Principal Investigator

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Elucidation of Molecular basis of inherited and acquired protein S deficiency as a thrombosis risk factorPrincipal Investigator

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KOJIMA Tetsuhito 小嶋哲人