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KOJIMA Tetsuhito  小嶋 哲人

ORCIDConnect your ORCID iD *help
Researcher Number 40161913
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2016 – 2019: 名古屋大学, 医学系研究科(保健), 教授
2017: 名古屋大学, 医学(系)研究科, 教授
2015: 名古屋大学, 医学部, 教授
2015: 名古屋大学, 大学院医学系研究科, 教授
2012 – 2015: 名古屋大学, 医学(系)研究科(研究院), 教授 … More
2013: 名古屋大学, 大学院医学系研究科, 教授
2012: 名古屋大学, 医学系研究科(保健), 教授
2000 – 2011: School of Medicine, Nagoya University, Professor, 医学部, 教授
2008: Nagoya University, 医学部・保健学科, 教授
1999: Nagoya University, School of Medicine, Associate Professor, 医学部, 助教授
1994 – 1998: Nagoya University School of Medicine, Assistant Professor, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Laboratory medicine / Hematology / Hematology / 血管生物学
Except Principal Investigator
Laboratory medicine / Hematology / Hematology / Laboratory medicine / General internal medicine(including psychosomatic medicine) / Medium-sized Section 90:Biomedical engineering and related fields
Keywords
Principal Investigator
Ryudocan / ヘパラン硫酸プロテオグリカン / bFGF / focal adhesion / fibronectin / 血管内皮細胞 / Tissue Factor Pathway Inhibitor(TFPI) / 組織修復 / ryudocan / 欠失マウス … More / マウス / midkine(MK) / ノックアウトマウス / 心筋梗塞 / トロンビン / アンチトロンビン・レジスタンス(ATR) / heparan sulfate proteoglycan / ryudocan (syndecan-4) / hypoxia / PAI-1 / NMMHCA / MYH9 / May-Hegglin anomaly / プロテインS(PS)欠損症 / PROS1遺伝子 / 遺伝子欠失 / プロモーター / ルシフェラーゼ・レポーター解析 / HepG2細胞 / エストラディオール(E2) / PS mRNA / 臨床血液学 / 静脈血栓塞栓症 / 先天性血栓性素因 / 遺伝子変異 / アンチトロンビン抵抗性 / 原因遺伝子変異 / アンチトロンビン欠損症 / プロテインC欠損症 / プロテインS欠損症 / アンチトロンビン抵抗性 / スクリ―ニング検査法 / アンチトロンビン欠損症 / プロテインC欠損症 / プロテインS欠損症 / スクリーニング検査法 / アンチトロンビン-レジスタンス(ATR) / プロトロンビン異常症 / 遺伝性血栓症 / 一塩基置換 / トロンボモジュリン / R593Lプロトロンビン-ノックインマウス / 相同組換え / アンチトロンビン・レジスタンス(ATR) / R593Lプロトロンビン-マウス / トロンボモジュリン/プロテインC経路 / R593Lプロトロンビン-マウス / トロンボモジュリン/プロテインC経路 / 血管内皮 / 特異抗体 / 免疫組織染色 / ミドカイン(MK) / Tisssue Factor Pathway Inhibitor (TFPI) / ミッドカイン(MK) / Inhibition radioimmuno-assay / Heparan Sulfate / Proteoglycan / Immuno-histochemistry / midkine / TFPI / mouse ryudocan / ryudocan cDNA / ryudocan gene / promoter activity / 血中濃度 / Heparan sulfate proteoglycan / null mice / ryudocan(syndecan-4) / 卵巣顆粒膜細胞 / 卵胞液 / 流動性維持 / 低酸素 / ヘパラン硝酸プリテオグリカン / Ryudocan(Syndecan-4) / VEGF / Lusiferase reporter assay / 抗凝固活性 / mouse / guranulosa cells / follicular fluid / maintain fluidity / Tissue-repairing / 腎臓機能障害 / カッパーカラゲナ / 閉塞性腎症 / カッパーカラゲナン / 細胞接着 / heparan sulfate proteoglvcan / deficient mice / renal damage / K-carrageenan / obstructive nephropathy / ストレス / 血栓性疾患 / 拘束ストレス負荷 / TF(組織因子) / 加齢(老齢) / 肥満 / TF(組織因子)発現 / 老齢 / 抗TNF-α抗体 / 加齢 / in situ hybridization法 / 血栓傾向 / competitive RT-PCR法 / stress / thrombotic diseases / restraint stress / TF / aged, older / obese / 巨大血小板性血小板減少症 / May-Hegglin異常症 / 免疫染色解析 / Alport徴候 / ノックインマウス / ノックイン / Cre-recombinase / 巨大血小板 / macrothrombocytopenia / immunostaining / Knock out mouse / Alport symptom / Knock in mouse / プロトロンビン / 遺伝子異常 / ATR検出・臨床検査法 / 自動化機器 / ATR残存凝固活性 / Na+結合領域 / Arg593Leuノックインマウス / アンチトロンビン / ジーンタ一ゲティング / R593Lノックインマウス / アンチトロンビン・レシスタンス(ATR) / 人工授精 / 内科 … More
Except Principal Investigator
血栓症 / ストレス / promoter analysis / Thrombosis / sphingosine kinase 1 / 脂肪細胞 / サイトカイン / 線溶 / gene expression / 遺伝子発現 / 転写調節 / Sp1 protein / 病態解析 / Ryudocan / プロテインS / platelet / thrombosis / スフィンゴシンキナーゼ1 / ATRA / 肥満 / 糖尿病 / アンチトロンビン抵抗性 / 国際情報交換 / プロモーター解析 / 老化 / 敗血症 / 静脈血栓塞栓症 / 血液流動性 / cDNA / 血管内皮 / 血栓性素因 / 分泌異常 / プロテインC / Thrombophilia / protein C deficiency / impaired secretion / TFPI / IL-1 / von Willebrand factor / Polymerase chain reaction / 血小板 / Antithrombin / Sindecan / recombination / Knock owt / LPS / May-Hegglin anomaly / NMMHCA / nerve growth factor / Trk A receptor / Fibrinolysis / Stress / Cytokine / Adipocyte / quantitative RT-PCR / acute leukemia / sphingolipid metabolites / GDNF / MEN2 type tumor / Plasminogen activator inhibitor-1 / 組織因子 / 凝固線溶 / セラミド / スフィンゴシン1リン酸 / スフィンゴシンキナーゼ2 / セラミドキナーゼ / 中性スフィンゴミエリナーゼ2 / スフィンゴシン1リン酸リアーゼ / ホスホリパーゼD1,ホスホリパーゼD2 / sphingosine 1-phosphate lyase / human lung cancer cell lines / real time RT-PCT / cellular S1P level / DNA pulldown assay and chromatin immunoprecipitation assay / GATA-4 protein / PLD1 transcription / 脂肪分化ならびに癌化 / 転写因子およびプロモーター領域結合部位 / 転写抑制機序 / ダウノルビシン / mRNA寿命の延長 / v-SRCガン遺伝子 / 3'-UTR / AUF1 / HuR / タンパク質リン酸化 / PKC alpha / 高血圧 / 臨床血液学 / プロトロンビン変異 / 変異プロトロンビン / 制御因子抵抗性 / 血栓症リスク / 検査法開発 / プロトロンビン / 遺伝子変異 / sphingolipid / metabolic enzyme / anti-cancer drug / human cancer cell lines / SPHK1 / Friend cell / c-Myb / chemical differentiation / human colon cancer cell / CD44 / S1P receptor 2 / ERK pathway / NSmase2 / MCF-7細胞株 / Sp1転写因子 / PKC delta / 炎症 / PAI-1 / 突然死 / 血管内皮細胞 / 心筋細胞 / 血栓 / 菌体毒素 / 腎糸球体 / 交感神経 / 神経細胞 / 病態検査学 / 危険因子 / プロトロンビン分子異常 / トロンボモジュリン抵抗性 / 血栓傾向 / Sphingolipid metabolism / Cancer cell / Stress response / Food ingredient / Phytochemical / Anti-cancer action / レスベラトロール / 酸性スフィンゴミエリナーゼ / 白血病細胞株 / 悪性腫瘍細胞株 / スフィンゴ脂質代謝 / 代謝酵素遺伝子発現調節 / SPHK2 / 血清除去 / ACDase / 前立腺癌細胞株 / アンドロジェン / USP2 / hypoxia / serum-depleted condition / CREB / transcription / ヘパラン硫酸 / 免疫組織染色 / 特異抗体 / Inhibition radioimmuno assay / alternative polyadenylation / ヒト染色体20q12 / Endothelial cell / Heparan Sulfate / Proteoglycan / Immuno-histochemistry / protein S欠損症 / ヘパラン硫酸プロテオグリカン / Ryudocan遺伝子 / プロモーター活性 / 生理的凝固阻止因子 / protein S deficiency / endothelium / heparan sulfate proteoglycan / ryudocan gene / promoter activity / プロテインC欠乏症 / 遺伝子異常 / COOH末梢除変異体 / 発現実験 / 立体構造変化 / 分子モデル / プロテインS欠乏症 / nonsense mutation / 血小板mRNA / exon skipping / alternative splicing / AAV / 遺伝子治療 / gene mutation / carboxyl-terminaldeletion / expression / conformational change / molecular model / TNF-α / 遺伝子発現量 / フイブリン沈着 / 血液凝固 / 線溶能 / Sepsis / TNF-alpha / Gene Expression / Fibrin deposition / GPIb / Polvmerase chain reaction / coronay heart disease / alanine scanning mutagenesis / von Willebrand因子 / ristocetin / botrocetin / mutant / GPIh / polymerase chain reaction / coronary heartdisease / alanine scanning mutagencsis / antithrombin / Svndecan / Knock out mouse / ポリクローナル抗体 / MEG-O1 / プロモータ解析 / スフィンゴシンキナーゼ / polyclonal antibody / MYH9異常症 / 先天性血小板異常症 / 先天性血小板減少症 / 血小板機能異常症 / 血小板減少症 / MYH9 disorders / Congenital platelet disorders / Congenital thrombocytopenia / Spl protein / anti human SPHK1 antibody / SPHK1 gene expression / neuronal apoptosis / all trans retinoic acid / 動脈硬化 / Obesity / Diabetes / Atherosclerosis / sphinosine kinase1 / myelodysplastic sundrome / anti-cancer drug sensitivity / MEN2 type promoter / myelodysplastic syndromes / RET signal / myelodysplastic syndrome / Elecrophysiology / フィブリン / ロングフライト症候群 / エコノミー症候群 / Fibrin / Gene expression / Lone flight thrombosis / 抗血栓薬 / 凝固第X因子 / アンチトロンビン / アンチトロンビン抵抗性検出法 / 変異型プロトロンビン / プロトロンビンアクチベータ / 遺伝性血栓性素因 / アジア人 / 国際学術調査 / 発症要因 / 予防治療戦 / protein S / protein C / 予防治療戦略 / 遺伝学 / 内科 / 栄養学 / 韓国 / ハンガリー / シンガポール / 英国 / 中国 / 巨核球 / 造血微小環境 / iPS細胞 / 骨髄微小環境 Less
  • Research Projects

    (36 results)
  • Research Products

    (315 results)
  • Co-Researchers

    (67 People)
  •  Development zeno-free/self-feeder culture system for an efficient iPSC derived platelet production

    • Principal Investigator
      Tamura Shogo
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Nagoya University
  •  Development of a new detection method in antithrombin resistance to avoid the effect of antithrombotic drug treatment

    • Principal Investigator
      TAKAGI AKIRA
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  Novel mutation search of antithrombin resistance and its pathological analysis research by mouse modelPrincipal Investigator

    • Principal Investigator
      Kojima Tetsuhito
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Stress response of cancer cells focusing the sphingolipid metabolism and its modulation by food ingredients

    • Principal Investigator
      MURATE Takashi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Chubu University
      Nagoya University
  •  Investigation into thrombophilia indigenous to Asian populations and establishment of new strategy for preventing thrombosis

    • Principal Investigator
      TSUDA Hiroko
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Nakamura Gakuen College
  •  Molecular elucidation of antithrombin resistance mechanism and development of thrombophilia model mouse.Principal Investigator

    • Principal Investigator
      Kojima Tetsuhito
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  Development of new examination methods for thrombotic tendency with TM resistance and FXa AT resistance

    • Principal Investigator
      TAKAGI AKIRA
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  Elucidation of mechanisms under prothrombotic state with aging

    • Principal Investigator
      Yamamoto Koji
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Saitama Medical University
      Nagoya University
  •  The involvement of sphingolipid metabolism in anti cancer drug sensitivity of malignant cells

    • Principal Investigator
      MURATE Takashi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  Gene analysis of a novel thrombotic risk factor; antithrombin-resistance.Principal Investigator

    • Principal Investigator
      KOJIMA Tetsuhito
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  Development of new analytical method for antithrombin resistance

    • Principal Investigator
      TAKAGI Akira
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  Involvement and abnormality of lysosphingolipid metabolic enzymes in malignant diseases

    • Principal Investigator
      MURATE Takashi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  Elucidation of molecular pathogenesis and control of thrombosis in metabolic syndrome

    • Principal Investigator
      YAMAMOTO Koji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Elucidation of Molecular basis of inherited and acquired protein S deficiency as a thrombosis risk factorPrincipal Investigator

    • Principal Investigator
      KOJIMA Tetsuhito
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  Aberrant expression of sphingosine kinase and its pathological significance of malignant tumors and neuronal degenerative diseases

    • Principal Investigator
      MURATE Takashi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  Analysis and regulation of aberrant expression of sties-responsive prothrombotic genes in a model of myocardial and cerebral infarction

    • Principal Investigator
      YAMAMOTO Koji
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Molecular mechanisms of thrombosis in mouse model induced by age and stressPrincipal Investigator

    • Principal Investigator
      KOJIMA Tetsuhito
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  Elucidation of molecular basis of May-Hegglin anomaly and its related disordes

    • Principal Investigator
      SAITO Hidehiko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      National Hospital Organization Nagoya Medical Center, Clinical Research Center
  •  Basic analysis of sphingolipid metabolising enzyme and its application to the diagnosis of hematological and neuronal diseases

    • Principal Investigator
      TAKASHI Murate
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  Analysis on thrombotic tendency in obesity and diabetes by use of model mouse

    • Principal Investigator
      YAMAMOTO Koji
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Molecular mechanisms of thrombosis in mouse model induced by age and stressPrincipal Investigator

    • Principal Investigator
      KOJIMA Tetsuhito
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  The significance of serum sphingosine 1-phospahte in hematological diseases and the regulatory mechanism of sphingosine kinase

    • Principal Investigator
      MURATE Takeshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  Antithrombin deficiency in mice results in embryonic lethality and thrombotic tendency.

    • Principal Investigator
      TAKAMATU Junki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  ストレス負荷により血栓形成傾向が促進されるか?(ストレス負荷マウスでは血液凝固線溶因子の組織内発現異常が認められるか?)

    • Principal Investigator
      SAITO Hidehiko
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Research on biological function of ryudocan by knockout mice analysis.Principal Investigator

    • Principal Investigator
      KOJIMA Tetsuhiro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Identification of the regulatory elements of human von Willebrand factor for binding to platelet GPlb.

    • Principal Investigator
      MATSUSHITA Tadashi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Down-regulation of murine tissue factor pathway inhibitor mRNA by endotoxin and tumor neerosis factor-alpha In vitro and In vivo.

    • Principal Investigator
      SAITO Hidehiko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  動脈硬化の発症病態に関わるHSPG・Ryudocanの機能解析Principal Investigator

    • Principal Investigator
      小嶋 哲人
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nagoya University
  •  Establishment of Ryudocan Null Mouse and ELISA for Blood Levels of RyudocanPrincipal Investigator

    • Principal Investigator
      KOJIMA Tetsuhito
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Ryudocan expression and its regulationPrincipal Investigator

    • Principal Investigator
      KOJIMA Tetsuhito
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  血管新生・動脈硬化症に関わる血管内皮HSPG・Ryudocanの機能解析Principal Investigator

    • Principal Investigator
      小嶋 哲人
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  Molecular Biological Analysis for Mechanism of Thombosis Regulation and Its Aplication for Clinical Desease.

    • Principal Investigator
      SAITO Hidehiko
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Molecular and Functional Analysis of Heparan sulfate Proteoglycan-Ryudocan.Principal Investigator

    • Principal Investigator
      KOJIMA Tetsuhito
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Molecular Biological Analysis for Mechanism of Thombosis Regulation and Its APlication for Clinical Desease.

    • Principal Investigator
      SAITO Hidehiko
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Molecular-patholical Analysis for the Biolocical Role of Ryudocan (Endothilal Heparan Sulfate Proteoglycan) on Vasculat Damage.Principal Investigator

    • Principal Investigator
      KOJIMA Tetsuhito
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      血管生物学
    • Research Institution
      Nagoya University
  •  Molecular and Pathological Analysis of Anticoagulant Heparan Sulfate Proteoglycan from Endothelial Cell

    • Principal Investigator
      SAITO Hidehiko
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University

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All Journal Article Presentation Book Patent

  • [Book] 血液疾患 最新の治療 2017-20192017

    • Author(s)
      兼松毅、小嶋哲人
    • Total Pages
      372
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Book] みんなに役立つ 血友病の基礎と臨床 改訂3版2016

    • Author(s)
      田村彰吾、小嶋哲人
    • Total Pages
      463
    • Publisher
      医歯ジャーナル社
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Book] ファーマナビゲーター抗凝固療法編2015

    • Author(s)
      高木夕希、小嶋哲人
    • Total Pages
      415
    • Publisher
      株式会社メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Book] Annual Review 2016血液2015

    • Author(s)
      高木夕希、小嶋哲人
    • Total Pages
      234
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Book] 血液疾患診療ハンドブック・改訂3版2015

    • Author(s)
      鈴木伸明、小嶋哲人
    • Total Pages
      591
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Book] 新・血栓止血血管学 凝固と炎症2015

    • Author(s)
      小嶋哲人
    • Total Pages
      189
    • Publisher
      金芳堂
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Book] 臨床検査法提要(改訂第34版)2015

    • Author(s)
      小嶋哲人、高木明
    • Total Pages
      1970
    • Publisher
      金原出版株式会社
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Book] 臨床検査法提要(改訂第34版)2015

    • Author(s)
      小嶋哲人、高木明
    • Total Pages
      21
    • Publisher
      金原出版株式会社
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Book] 新・血栓止血血管学 抗凝固と線溶2015

    • Author(s)
      小嶋哲人
    • Total Pages
      133
    • Publisher
      金芳堂
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Book] 「EBM血液疾患の治療 2015-2016」2014

    • Author(s)
      村田萌、小嶋哲人
    • Total Pages
      555
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Book] 徹底ガイド DICのすべて2014-152014

    • Author(s)
      小嶋哲人
    • Total Pages
      392
    • Publisher
      総合医学社
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Book] 改訂第8版 内科学書 Vol.6 血液・造血器疾患、神経疾患(分担)2013

    • Author(s)
      小嶋哲人
    • Total Pages
      493
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Book] 「みんなに役立つ 血友病の基礎と臨床 改訂版」2012

    • Author(s)
      村田萌、小嶋哲人
    • Total Pages
      423
    • Publisher
      医歯ジャーナル社
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Book] あなたも名医!新しい経口抗凝固薬、どう使う2012

    • Author(s)
      小嶋哲人
    • Publisher
      日本医事新報社
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Book] フォンダパリヌクスの基礎循環器内科医のためのXa阻害薬のすべて2012

    • Author(s)
      小嶋哲人
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Book] 「あなたも名医!新しい経口抗凝固薬、どう使う」2012

    • Author(s)
      小嶋哲人
    • Total Pages
      162
    • Publisher
      日本医事新報社
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Book] 先天性凝固阻止因子欠乏症(AT,PC,PS欠損症)わかりやすい血栓と止血の臨床2011

    • Author(s)
      小嶋哲人
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Book] 抗血栓薬の最前線 -基礎と臨床2011

    • Author(s)
      小嶋哲人
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Book] わかりやすい血栓と止血の臨床2011

    • Author(s)
      小嶋哲人
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Book] 血液疾患 最新の治療 2011-20132010

    • Author(s)
      小嶋哲人
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Book] 血液疾患最新の治療2011-20132010

    • Author(s)
      小嶋哲人
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Book] I.基礎 3.血友病の病態 3)血友病Bの分子病態血友病の基礎と臨床(白幡聡編)2009

    • Author(s)
      奥村薫、小嶋哲人
    • Publisher
      医歯ジャーナル社
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Book] In講義録血液・造血器疾患(小澤敬也/直江知樹/坂田洋一編)I.血液・造血器を深く知るための基本講義B.止血・凝固システムを学ぶ凝固系制御機構2008

    • Author(s)
      小嶋哲人
    • Publisher
      株式会社メディカルビュー社
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Book] 講義録 血液・造血器疾患学2008

    • Author(s)
      小嶋哲人
    • Total Pages
      301
    • Publisher
      株式会社メデイカルビュー社
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Book] Hypercoagulable States. K. Tanaka, and E.W. Davie, eds; Recent Advances in Thrombosis and Hemostasis2008

    • Author(s)
      T Kojima and H Saito
    • Publisher
      Springer(printed in Japan)
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Book] 抗凝固薬の適正な使い方(第2版)2008

    • Author(s)
      小嶋哲人
    • Total Pages
      430
    • Publisher
      医書薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Book] In抗凝固薬の適正な使い方(第2版)櫻川信男/上塚芳郎/和田秀夫編Chapter4. その他の抗凝固薬Paragraph1.ヘパリン、低分子量ヘパリン2008

    • Author(s)
      小嶋哲人
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Book] Xa阻害薬のすべて(抗凝固薬の歴史とXa阻害薬の開発目的を探る)2007

    • Author(s)
      小嶋哲人(池田康夫)
    • Total Pages
      233
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Book] Part 4. Xa阻害薬の薬理的特徴をみる1. 抗凝固薬の歴史とXa阻害薬の開発目的を探るXa阻害薬のすべて(池田康夫/坂田洋一/丸山征郎(編))2007

    • Author(s)
      小嶋哲人
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Book] 先天性血栓性疾患の治療法v.凝固・血小板「EBM血液疾患の治療2008-2009」(押味和夫/別所正美/岡本真一郎/加藤淳(編))2007

    • Author(s)
      岩崎年宏, 小嶋哲人
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Book] 先天性アンチトロンビン欠損症C.血小板・凝固線溶「専門医のための薬物療法Q&A : 血液」(押味和夫/長澤俊郎/小松則夫(編))2007

    • Author(s)
      小嶋哲人
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Book] 三輪・血液病学2006

    • Author(s)
      小嶋哲人, (浅野茂隆ら監修)
    • Total Pages
      2070
    • Publisher
      文光堂
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590490
  • [Book] MIWA HEMATOLOGY2006

    • Author(s)
      T.Kojima, (ed.by S.Asano, et al.)
    • Total Pages
      2070
    • Publisher
      Bunko-do
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590490
  • [Book] 三輪・血液病学2006

    • Author(s)
      小嶋哲人(浅野茂隆ら監修)
    • Total Pages
      2070
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-17590490
  • [Book] 血液の事典2004

    • Author(s)
      小嶋哲人(平井久丸ら編)
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-15591000
  • [Book] Igaku Shoin's Medical Dictionary2003

    • Author(s)
      T.Kojima(ed.by M.Ito, et al.)
    • Total Pages
      30
    • Publisher
      Igaku Shoin
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591000
  • [Book] 医学大事典2003

    • Author(s)
      小嶋哲人(伊藤正男ら編)
    • Publisher
      医学書院
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591000
  • [Journal Article] Higher FVIII:C measured by chromogenic substrate assay than by one-stage assay is associated with silent hemophilic arthropathy2020

    • Author(s)
      Mika Ogawa, Nobuaki Suzuki, Nobunori Takahashi, Shogo Tamura, Atsuo Suzuki, Sachiko Suzuki, Yuua Hattori, Misaki Kakihara, Takeshi Kanematsu, Toshihisa Kojima, Akira Katsumi, Fumihiko Hayakawa, Tetsuhito Kojima, Naoki Ishiguro , Hitoshi Kiyoi , Tadashi Matsushita
    • Journal Title

      Thrombosis Research

      Volume: 188 Pages: 103-105

    • DOI

      10.1016/j.thromres.2020.01.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08853, KAKENHI-PROJECT-18H02835, KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-17K09902, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K19910
  • [Journal Article] Apparent synonymous mutation F9 c.87A>G causes secretion failure by in-frame mutation with aberrant splicing2019

    • Author(s)
      Odaira K, Tamura S, Suzuki N, Kakihara M, Hattori Y, Tokoro M, Suzuki S, Takagi A, Katsumi A, Hayakawa F, Okamoto S, Suzuki A, Kanematsu T, Matsushita T, Kojima T.
    • Journal Title

      Thrombosis Research

      Volume: 179 Pages: 95-103

    • DOI

      10.1016/j.thromres.2019.04.022

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08853, KAKENHI-PROJECT-18H02835, KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-17K09902, KAKENHI-PROJECT-18K19910
  • [Journal Article] Successful Perioperative Combination of High-Dose FVIII Therapy Followed by Emicizumab in a Patient with Hemophilia A with Inhibitors.2019

    • Author(s)
      Okamoto Shuichi、Suzuki Nobuaki、Suzuki Atsuo、Suzuki Sachiko、Tamura Shogo、Suzuki Mochihito、Takahashi Nobunori、Kojima Toshihisa、Kanematsu Takeshi、Kojima Tetsuhito、Kiyoi Hitoshi、Ishiguro Naoki、Matsushita Tadashi
    • Journal Title

      TH Open.

      Volume: 03

    • DOI

      10.1055/s-0039-3401001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-17K09902, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-18K19910
  • [Journal Article] Apparent synonymous mutation F9 c.87A>G causes secretion failure by in-frame mutation with aberrant splicing.2019

    • Author(s)
      Odaira K, Tamura S, Suzuki N, Kakihara M, Hattori Y, Tokoro M, Suzuki S, Takagi A, Katsumi A, Hayakawa F, Okamoto S, Suzuki A, Kanematsu T, Matsushita T, Kojima T
    • Journal Title

      Thrombosis Research

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Journal Article] Molecular basis of SERPINC1 mutations in Japanese patients with antithrombin deficiency.2019

    • Author(s)
      Tamura Shogo、Hashimoto Erika、Suzuki Nobuaki、Kakihara Misaki、Odaira Koya、Hattori Yuna、Tokoro Mahiru、Suzuki Sachiko、Takagi Akira、Katsumi Akira、Hayakawa Fumihiko、Suzuki Atsuo、Okamoto Shuichi、Kanematsu Takeshi、Matsushita Tadashi、Kojima Tetsuhito
    • Journal Title

      Thromb Res.

      Volume: 178 Pages: 159-170

    • DOI

      10.1016/j.thromres.2019.04.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09451, KAKENHI-PROJECT-19K08853, KAKENHI-PROJECT-18H02835, KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-17K09902, KAKENHI-PROJECT-18K19910
  • [Journal Article] Molecular basis of SERPINC1 mutations in Japanese patients with antithrombin deficiency.2019

    • Author(s)
      Tamura S, Hashimoto E, Suzuki N, Kakihara M, Odaira K, Hattori Y, Tokoro M, Suzuki S, Takagi A, Katsumi A, Hayakawa F, Suzuki A, Okamoto S, Kanematsu T, Matsushita T, Kojima T
    • Journal Title

      Thrombosis Research

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Journal Article] Combined deficiency of factors V and VIII by chance coinheritance of parahaemophilia and haemophilia A, but not by mutations of either LMAN1 or MCFD2, in a Japanese family2018

    • Author(s)
      Suzuki S, Nakamura Y, Suzuki N, Yamazaki T, Takagi Y, Tamura S, Takagi A, Kanematsu T, Matsushita T, Kojima T
    • Journal Title

      Haemophilia

      Volume: 24

    • DOI

      10.1111/hae.13360

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09825, KAKENHI-PROJECT-17H05073
  • [Journal Article] アンチトロンビン抵抗性の診断 -検査法を中心に-2018

    • Author(s)
      高木明、田村彰吾、小嶋哲人
    • Journal Title

      日本検査血液学会誌

      Volume: 19 Pages: 393-400

    • Data Source
      KAKENHI-PROJECT-16K08967
  • [Journal Article] Familial pulmonary thromboembolism with a prothrombin mutation and antithrombin resistance2018

    • Author(s)
      10)Yoshida R, Seki S, Hasegawa J, Koyama T, Yamazaki K, Takagi A, Kojima T, Yoshimura M
    • Journal Title

      Journal of Cardiology Cases

      Volume: in press Pages: 197-199

    • DOI

      10.1016/j.jccase.2018.02.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09825, KAKENHI-PROJECT-16K08967
  • [Journal Article] Optimisation of antithrombin resistance assay as a practical clinical laboratory test: development of prothrombin activator using factors Xa/Va and automation of assay.2018

    • Author(s)
      Tamura S.、Suga Y.、Tanamura M.、Murata-Kawakami M.、Takagi Y.、Hottori Y.、Kakihara M.、Suzuki S.、Takagi A.、Kojima T.
    • Journal Title

      Int J Lab Hematol.

      Volume: 40 Pages: 312-319

    • DOI

      10.1111/ijlh.12786

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19910, KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-16K08967, KAKENHI-PROJECT-16K09825
  • [Journal Article] Vwf K1362A resulted in failure of protein synthesis in mice.2018

    • Author(s)
      Sanda N, Suzuki N, Suzuki A, Kanematsu T, Kishimoto M, Hasuwa H, Takagi A, Kojima T, Matsushita T, Nakamura S
    • Journal Title

      Int J Hematol.

      Volume: in press Pages: 428-435

    • DOI

      10.1007/s12185-017-2394-y

    • NAID

      120006501193

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09825, KAKENHI-PROJECT-17K09902
  • [Journal Article] Diagnosis and treatment guidelines for aberrant portal hemodynamics.2017

    • Author(s)
      Moriyasu F, Furuichi Y, Tanaka A, Takikawa H, Yoshida H, Sakaida I, Obara K, Hashizume M, Kage M, Ohfuji S, Kitano S, Kawasaki S, Kokubu S, Matsutani S, Eguchi S, Shiomi S, Kojima T, Maehara Y, Kuniyoshi Y.
    • Journal Title

      Hepatol Res.

      Volume: 47 Pages: 373-386

    • DOI

      10.1111/hepr.12862

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Journal Article] Clinical and biochemical characterization of the Prothrombin Belgrade mutation in a large Serbian pedigree: new insights into antithrombin resistance mechanism.2017

    • Author(s)
      Miljic P, Gvozdenov M, Takagi Y, Takagi A, Pruner I, Dragojevic M, Tomic B, Bodrozic J, Kojima T, Radojkovic D, Djordjevic V.
    • Journal Title

      J Thromb Haemost.

      Volume: 15 Pages: 670-677

    • DOI

      10.1111/jth.13618

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08967, KAKENHI-PROJECT-16K09825
  • [Journal Article] In vitro exploration of latent prothrombin mutants conveying antithrombin resistance2017

    • Author(s)
      Tamura S, Murata-Kawakami M, Takagi Y, Suzuki S, Katsumi A, Takagi A, Kojima T.
    • Journal Title

      Thrombosis Research

      Volume: 159 Pages: 33-38

    • DOI

      10.1016/j.thromres.2017.09.020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09451, KAKENHI-PROJECT-16K08967, KAKENHI-PROJECT-16K09825, KAKENHI-PROJECT-17H05073
  • [Journal Article] First case report of hemophilia B Leyden in Japan.2017

    • Author(s)
      Yamashita A, Nagae C, Mori M, Ashikaga T, Kojima T, Taki M
    • Journal Title

      Int J Hematol.

      Volume: 106 Pages: 135-137

    • DOI

      10.1007/s12185-017-2194-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Journal Article] Increased acid ceramidase expression depends on upregulation of androgen-dependent deubiquitinases, USP2, in a human prostate cancer cell line, LNCaP2016

    • Author(s)
      Naoki Mizutani, Minami Inoue, Yukari Omori, Hiromi Ito, Keiko Tamiya-Koizumi, Akira Takagi, Tetsuhito Kojima, Mitsuhiro Nakamura, Soichiro Iwaki, Masahiro Nakatochi, Motoshi Suzuki, Yoshinori Nozawa, Takashi Murate
    • Journal Title

      J Biochem.

      Volume: 印刷中 Pages: 309-319

    • DOI

      10.1093/jb/mvv039

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460203, KAKENHI-PROJECT-26460674, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-26290051
  • [Journal Article] Syndecan 4 mediates Nrf2-dependent expansion of bronchiolar progenitors that protect against lung inflammation.2016

    • Author(s)
      Santoso A, Kikuchi T, Tode N, Hirano T, Komatsu R, Damayanti T, Motohashi H, Yamamoto M, Kojima T, Uede T, Nukiwa T, Ichinose M
    • Journal Title

      Mol Ther

      Volume: 24 Pages: 41-52

    • DOI

      10.1038/mt.2015.153

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-23390219, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-15K15316
  • [Journal Article] Missense mutations in the gene encoding prothrombin corresponding to Arg596 cause antithrombin resistance and thrombomodulin resistance.2016

    • Author(s)
      Takagi Y, Murata M, Kozuka T, Nakata Y, Hasebe R, Tamura S, Takagi A, Matsushita T, Saito H, Kojima T.
    • Journal Title

      Thromb Haemost.

      Volume: 116 Pages: 1-10

    • DOI

      10.1160/th16-03-0223

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16J08029, KAKENHI-PROJECT-26860723, KAKENHI-PROJECT-16K08967, KAKENHI-PROJECT-16K09825
  • [Journal Article] Progestin isoforms provide different levels of protein S expression in HepG2 cells.2016

    • Author(s)
      Kozuka, Toshihiro Tamura, Shogo Kawamura, Nami Nakata, Yukiko Hasebe, Ryo Makiyama, Ayumi Takagi, Yuki Murata, Moe Mizutani, Naoki Takagi, Akira Kojima, Tetsuhito
    • Journal Title

      Thromb Res.

      Volume: 145 Pages: 40-45

    • DOI

      10.1016/j.thromres.2016.07.007

    • NAID

      120005895232

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26860723, KAKENHI-PROJECT-16K09825
  • [Journal Article] The first case of antithrombin-resistant prothrombin Belgrade mutation in Japanese2016

    • Author(s)
      Kishimoto M, Suzuki N, Murata M, Ogawa M, Kanematsu T, Takagi A, Kiyoi H, Kojima T, Matsushita T
    • Journal Title

      Ann Hematol.

      Volume: 95 Pages: 541-542

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Journal Article] Distinct X chromosomal rearrangements in four haemophilia B patients with entire F9 deletion.2016

    • Author(s)
      Nakamura Y, Ando Y, Takagi Y, Murata M, Kozuka T, Nakata Y, Hasebe R, Takagi A, Matsushita T, Shima M, Kojima T.
    • Journal Title

      Haemophilia.

      Volume: 22 Pages: 433-439

    • DOI

      10.1111/hae.12849

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Journal Article] 新たな血栓性素因:アンチトロンビンレジスタンス2016

    • Author(s)
      小嶋哲人、高木明、村田萌、高木夕希
    • Journal Title

      日本産婦人科・新生児血液学会誌

      Volume: 25 Pages: 66-77

    • Data Source
      KAKENHI-PROJECT-16K08967
  • [Journal Article] Serum Syndecan-4 as a Possible Biomarker in Patients With Acute Pneumonia.2016

    • Author(s)
      Nikaido T, Tanino Y, Wang X, Sato S, Misa K, Fukuhara N, Sato Y, Fukuhara A, Uematsu M, Suzuki Y, Kojima T, Tanino M, Endo Y, Tsuchiya K, Kawamura I, Frevert C, Munakata M
    • Journal Title

      J Infect Dis.

      Volume: 212 Pages: 1500-1508

    • DOI

      10.1093/infdis/jiv234

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08359, KAKENHI-PROJECT-25460596, KAKENHI-PROJECT-26460523, KAKENHI-PROJECT-25293129
  • [Journal Article] The first case of antithrombin-resistant prothrombin Belgrade mutation in Japanese.2016

    • Author(s)
      Kishimoto M, Suzuki N, Murata M, Ogawa M, Kanematsu T, Takagi A, Kiyoi H, Kojima T, Matsushita T
    • Journal Title

      Ann Hematol.

      Volume: 95 Pages: 541-542

    • DOI

      10.1007/s00277-015-2533-6

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Journal Article] 新たな血栓性素因:アンチトロンビンレジスタンス2016

    • Author(s)
      小嶋哲人、高木明、村田萌、高木夕希
    • Journal Title

      日本産婦人科・新生児血液学会誌

      Volume: 25 Pages: 66-72

    • Data Source
      KAKENHI-PROJECT-25460683
  • [Journal Article] SVA retrotransposition in exon 6 of the coagulation factor IX gene causing severe hemophilia B.2015

    • Author(s)
      Nakamura Y, Murata M, Takagi Y, Kozuka T, Nakata Y, Hasebe R, Takagi A, Kitazawa JI, Shima M, Kojima T.
    • Journal Title

      Int J Hematol

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591421
  • [Journal Article] High prophylactic LMWH dose successfully suppressed hemostatic activation in pregnant woman with a new prothrombin c.1787G>A mutation.2015

    • Author(s)
      Kovac M, Elezovic I, Mikovic V, Djordjevic V, Radojkovic D, Lalic-Cosic S, Murata M, Takagi A, Kojima T
    • Journal Title

      Thromb Res

      Volume: 135 Pages: 420-422

    • DOI

      10.1016/j.thromres.2014.12.008

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-14J03741, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-25460683
  • [Journal Article] アンチトロンビンレジスタンス ―新しい遺伝性血栓性素因―2015

    • Author(s)
      小嶋哲人、高木明、村田萌、高木夕希
    • Journal Title

      臨床血液

      Volume: 56 Pages: 632-637

    • NAID

      130005093096

    • Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Journal Article] Antithrombin resistance: a new mechanism of inherited thrombophilia2015

    • Author(s)
      小嶋哲人, 高木明, 村田萌, 高木夕希
    • Journal Title

      Jpn. J. Clin. Hematol.

      Volume: 56 Issue: 6 Pages: 632-638

    • DOI

      10.11406/rinketsu.56.632

    • NAID

      130005093096

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-14J03741, KAKENHI-PROJECT-25293129
  • [Journal Article] SVA retrotransposition in exon 6 of the coagulation factor IX gene causing severe hemophilia B.2015

    • Author(s)
      Mizutani N, Omori Y, Tanaka K, Ito H, Takagi A, Kojima T, Nakatochi M, Ogiso H, Kawamoto Y, Nakamura M, Suzuki M, Kyogashima M, Koizumi K, Nozawa Y, Murate T.
    • Journal Title

      J Cell Biochem.

      Volume: 116 Pages: 134-139

    • DOI

      10.1002/jcb.25173

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-26460674, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-26290051
  • [Journal Article] RhoF Promotes Murine Marginal Zone B Cell Development.2014

    • Author(s)
      Kishimoto M, Matsuda T, Yanase S, Katsumi A, Sezuki N, Ikejiri M, Takagi A, Ikawa M, Kojima T, Kunishima S, Kiyoi H, Naoe T, Matsushita T, Maruyama M
    • Journal Title

      Nagoya J Med Sci.

      Volume: 76 Pages: 293-305

    • NAID

      120005468127

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Journal Article] Antithrombin-resistant prothrombin Yukuhashi mutation also causes thrombomodulin resistance in fibrinogen clotting but not in protein C activation2014

    • Author(s)
      Takagi Y, Kato I, Ando Y, NakamuraY, Murata M, Takagi A, Murate T, Kojima T
    • Journal Title

      Thromb Res

      Volume: 134 Pages: 914-917

    • DOI

      10.1016/j.thromres.2014.07.040

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-14J03741, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-25460683
  • [Journal Article] Development of a new laboratory test to evaluate antithrombin resistance in plasma.2014

    • Author(s)
      Murata M, Takagi A, Suzuki A, Okuyama E, Takagi Y, Ando Y, Kato I, Nakamura Y, Murate T, Matsushita T, Saito H, Kojima T.
    • Journal Title

      Thromb Res.

      Volume: 133 Pages: 293-298

    • DOI

      10.1016/j.thromres.2013.11.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-25461445
  • [Journal Article] Rhof promotes murine marginal zone B cell development.2014

    • Author(s)
      Kishimoto M, Matsuda T, Yanase S, Katsumi A, Suzuki N, Ikejiri M, Takagi A, Ikawa M, Kojima T, Kunishima S, Kiyoi H, Naoe T, Matsushita T, Maruyama M.
    • Journal Title

      Nagoya J Med Sci

      Volume: 76 Pages: 293-305

    • NAID

      120005468127

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591421
  • [Journal Article] Development of new laboratory test to evaluate antithrombin resistance in plasma2014

    • Author(s)
      Murata M, Takagi A, Suzuki A, Okuyama E, Takagi Y, Ando Y, Kato I, Nakamura Y, Murate T, Matsushita T, Saito H, Kojima T.
    • Journal Title

      Thromb Res.

      Volume: 133 Pages: 293-299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Journal Article] 1Current venous thromboembolism management and its outcomes in Japan: the nationwide JAVA observational study.2014

    • Author(s)
      Nakamura M, Miyata T, Ozeki Y, Takayama M, Komori K, Yamada N, Origasa H, Satokawa H, Maeda H, Tanabe N, Unno N, Shibuya T, Tanemoto K, Kondo K, Kojima T.
    • Journal Title

      Circ J.

      Volume: 78 Pages: 708-717

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Journal Article] Phosphorylated Sp1 is the regulator of DNA-PKcs and DNA ligase IV transcription of daunorubicin-resistant leukemia cell lines2014

    • Author(s)
      Nishida Y, Mizutani N, Inoue M, Omori Y, Tamiya-Koizumi K, Takagi A, Kojima T, Suzuki M, Nozawa Y, Minami Y, Ohnishi K, Naoe T, Murate T.
    • Journal Title

      Biochim Biophys Acta

      Volume: 1839 Pages: 265-274

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460674
  • [Journal Article] 新たな血栓性素因:アンチトロンビンレジスタンス2014

    • Author(s)
      小嶋哲人
    • Journal Title

      日本検査血液学会雑誌

      Volume: 15 Pages: 289-296

    • Data Source
      KAKENHI-PROJECT-25293129
  • [Journal Article] A complex genomic abnormality found in a patient with antithrombin deficiency and autoimmune disease-like symptoms2014

    • Author(s)
      Kato I, Takagi Y, Ando Y, Nakamura Y, Murata M, Takagi A, Murate T, Matsushita T, Nakashima T, Kojima T.
    • Journal Title

      Int J Hematol.

      Volume: 100 Pages: 200-205

    • DOI

      10.1007/s12185-014-1596-9

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-25460683, KAKENHI-PROJECT-25461445
  • [Journal Article] Molecular mechanisms of syndecan-4 upregulation by TNF-α in the endothelium-like EAhy926 cells.2013

    • Author(s)
      Okuyama E, Suzuki A, Murata M, Ando Y, Kato I, Takagi Y, Takagi A, Murate T, Saito H, Kojima T.
    • Journal Title

      J Biochem

      Volume: 154 Pages: 41-50

    • DOI

      10.1093/jb/mvt024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591421
  • [Journal Article] Comparison of the efficacy of ribavirin plus peginterferon-alfa2b for chronic hepatitis C infection in patients with and without coagulation disorders.2013

    • Author(s)
      Honda T, Katano Y, Kuzuya T, Hayashi K, Ishigami M, Itoh A, Hirooka Y, Nakano I, Ishikawa T, Toyoda H, Kumada T, Yamamoto K, Matsushita T, Kojima T, Takamatsu J, Goto H
    • Journal Title

      Journal of Medical Virology

      Volume: 85(2) Pages: 228-234

    • DOI

      10.1002/jmv.23444

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-23590970, KAKENHI-PROJECT-23592689, KAKENHI-PROJECT-24591421
  • [Journal Article] Sphingosine kinase 1 expression is downregulated during differentiation of Friend cells due to decreased c-MYB2013

    • Author(s)
      Mizutani N, Kobayashi M, Sobue S, Ichihara M, Ito H, Tanaka K, Iwaki S,Fujii S,Ito Y, Tamiya-Koizumi K, Takagi A, Kojima T, Naoe T, Suzuki M, Nakamura M, Banno Y, Nozawa Y, Murate T.
    • Journal Title

      Biochem Biophys Acta

      Volume: 1833 Pages: 1006-1016

    • DOI

      10.1016/j.bbamcr.2013.01.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590139, KAKENHI-PROJECT-23590667, KAKENHI-PROJECT-24590185, KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-24790164
  • [Journal Article] Ribavirin-induced intracellular GTP depletion activates transcription elongation in coagulation factor VII gene expression2013

    • Author(s)
      Suzuki A, Miyawaki Y, Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Takagi A, Murate T, Saito H, Kojima T
    • Journal Title

      Biochemical J

      Volume: 449(1) Pages: 231-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Ribavirin-induced intracellular GTP depletion activates transcription elongation in coagulation factor FVII gene expression.2013

    • Author(s)
      Atsuo Suzuki, et al.
    • Journal Title

      Biochem J.

      Volume: 449 Pages: 231-239

    • DOI

      10.1042/bj20121286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J05159, KAKENHI-PROJECT-22590524
  • [Journal Article] A novel prothrombin mutation in two families with prominent thrombophilia- the first cases of antithrombin resistance in a Caucasian population2013

    • Author(s)
      Djordjevic V, Kovac M, Miljic P, Murata M, Takagi A, Pruner I, Francuski D, Kojima T, Radojkovic D.
    • Journal Title

      J Thromb Haemost.

      Volume: 11 Pages: 1936-1939

    • DOI

      10.1111/jth.12367

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25460683
  • [Journal Article] Impact of antithrombin deficiency on efficacy of edoxaban and antithrombin-dependent anticoagulants, fondaparinux, enoxaparin, and heparin.2013

    • Author(s)
      Fukuda T, Kamisato C, Honda Y, Matsushita T, Kojima T, Furugohri T, Morishima Y, Shibano T
    • Journal Title

      Thromb Res.

      Volume: 131 Pages: 540-546

    • DOI

      10.1016/j.thromres.2013.04.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Journal Article] A novel prothrombin mutation in two families with prominent thrombophilia- the first cases of antithrombin resistance in a Caucasian population.2013

    • Author(s)
      Suzuki N, Kunishima S, Ikejiri M, Maruyama S, Sone M, Takagi A, Ikawa M, Okabe M, Kojima T, Saito H, Naoe T, Matsushita T.
    • Journal Title

      J Thromb Haemost.

      Volume: 8 Pages: 1936-1939

    • DOI

      10.1371/journal.pone.0071187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591429, KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-24591421, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293129
  • [Journal Article] Thrombosis from a prothrombin mutation conveying antithrombin resistance2012

    • Author(s)
      Miyawaki Y, Suzuki A, Fujita J, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Kunishima S, Sakai M, Okamoto K, Matsushita T, Naoe T, Saito H, Kojima K
    • Journal Title

      N Engl J Med

      Volume: 366 Pages: 2390-2396

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Transcriptional Regulation of Neutral Sphingomyelinase 2 in All-Trans Retinoic Acid-treated Human Breast Cancer Cell Line, MCF-7. 20122012

    • Author(s)
      Ito H
    • Journal Title

      J Biochem

      Volume: 151 Pages: 599-610

    • DOI

      10.1093/jb/mvs037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790532, KAKENHI-PUBLICLY-23107712, KAKENHI-PROJECT-23590667, KAKENHI-PROJECT-23659664, KAKENHI-PROJECT-24590185, KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-24780125
  • [Journal Article] Thrombosis from a prothrombin mutation conveying antithrombin resistance2012

    • Author(s)
      Miyawaki Y, Suzuki A, Fujita J, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Kunishima S, Sakai M, Okamoto K, Matsushita T, Naoe T, Saito H, Kojima T
    • Journal Title

      The NEW ENGLAND JOURNAL of MEDICINE

      Volume: 366 Pages: 2390-2396

    • DOI

      10.1056/nejmoa1201994

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-22591059, KAKENHI-PROJECT-22591755, KAKENHI-PROJECT-22659114, KAKENHI-PROJECT-23591429
  • [Journal Article] A survey of the clinical course and management of Japanese patients deficient in natural anticoagulants.2012

    • Author(s)
      Yokoyama k, Kojima T, Sakata Y, Kawasaki T, Tsuji H, Miyata T, Okamoto S, Murata M
    • Journal Title

      Clin Appl Thromb Hemost

      Volume: 18(5) Pages: 506-513

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Role of down-regulated neutral ceramidase during all-trans retinoic acid-induced neuronal differentiation in SH-SY5Y neuroblastoma cells2012

    • Author(s)
      Kouji Tanaka
    • Journal Title

      J. Biochem.

      Volume: (印刷中) Pages: 611-20

    • DOI

      10.1093/jb/mvs033

    • NAID

      10031166103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790156, KAKENHI-PROJECT-22590139, KAKENHI-PUBLICLY-23107712, KAKENHI-PROJECT-23590667, KAKENHI-PROJECT-23659664, KAKENHI-PROJECT-24590364, KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-24790164
  • [Journal Article] The author reply2012

    • Author(s)
      Matsushita T, Saito H, Kojima T
    • Journal Title

      N Engl J Med

      Volume: 367 Pages: 1069-1070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Thrombosis from a Prothrombin Mutastion Conveying Antithrombin Resistance2012

    • Author(s)
      Yuhri Miyawaki, Atsuo Sizuki, Junko Fujita, Asuka Maki, Eriko Okuyama, Moe Murata, Akira Takagi, Takashi Murate, Shinji Kunishima, Michio Sakata, Kohji Okamoto, Tadashi Matsushita, Tomoki Naoe, Hidehiko Saito, Tetsuhito Kojima
    • Journal Title

      The NEW ENGLAND JOURNAL of MEDICINE

      Volume: 366巻 Pages: 2390-2396

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659114
  • [Journal Article] A novel ENG mutation causing impaired co-translational processing of endoglin associated with hereditary hemorrhagic telangiectasia.2012

    • Author(s)
      Suzuki A, Nakashima D, Miyawaki Y, Fujita J, Maki A, Fujimori Y, Takagi A, Murate T, Teranishi M, Matsushita T, Saito H, Kojima T
    • Journal Title

      Thromb Res

      Volume: 129(5)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] A possible mechanism for Inv22-related F8 large deletions in severe hemophilia A patients with high responding factor VIII inhibitors.2012

    • Author(s)
      J. Fujita, Y. Miyawaki, A. Suzuki, et al.
    • Journal Title

      J Thromb Haemost.

      Volume: 10 Pages: 2099-107

    • DOI

      10.1111/j.1538-7836.2012.04897.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J05159, KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-22591059
  • [Journal Article] Syndecan-4 Regulates Early Neutrophil Migration and Pulmonary Inflammation in Response to Lipopolysaccharide.2012

    • Author(s)
      Tanino Y, Chang MY, Wang X, Gill SE, Skerrett S, McGuire JK, Sato S, Nikaido T, KojimaT, Munakata M, Mongovin S, Parks WC, Martin TR, Wight TN, Charles W
    • Journal Title

      Am J Respir Cell Mol Biol.

      Volume: 47(2) Pages: 196-202

    • DOI

      10.1165/rcmb.2011-0294oc

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] A novel ENG mutation causing impaired co-translational processing of endoglin associated with hereditary hemorrhagic telangiectasia.2012

    • Author(s)
      Atsuo Suzuki
    • Journal Title

      Thromb Res.

      Volume: (in press)

    • DOI

      10.1016/j.thromres.2011.12.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J05159, KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-22591059
  • [Journal Article] A possible mechanism for Inv22-related F8 large deletions in severe hemophilia a patients with high responding factor VIII inhibitors2012

    • Author(s)
      Fujita J, Miyawaki Y, Suzuki A, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Suzuki N, Matsushita T, Saito H, Kojima T
    • Journal Title

      J Thromb Haemost

      Volume: 10(10) Pages: 2099-2107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Syndecan-4 prevents cardiac rupture and dysfunction after myocardial infarction.2011

    • Author(s)
      Matsui Y, Ikesue M, Danzaki K, Morimoto J, Sato M, Tanaka S, Kojima T, Tsutsui H, Uede T
    • Journal Title

      Circ Res

      Volume: 108(11) Pages: 1328-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Venous thromboembolism and a race-specific genetic variation, protein S K196E, in Japanese.2011

    • Author(s)
      Miyata T, Hamasaki N, Wada H, Kojima T
    • Journal Title

      J Thromb Haemost

      Volume: (Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Historical perspective and future direction of coagulation research2011

    • Author(s)
      H Saito, T Matsushita, T Kojima
    • Journal Title

      J Thromb Haemost

      Volume: Suppl 1 Pages: 352-363

    • DOI

      10.1111/j.1538-7836.2011.04362.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Life-threatening hemorrhage and prolonged wound healing are remarkable phenotypes manifested by complete plasminogen activator inhibitor-1 deficiency in humans2011

    • Author(s)
      Iwaki T, Tanaka A, Miyawaki Y, Suzuki A, Kobayashi T, Takamatsu J, Matsushita T, Umemura K, Urano T, Kojima T, Terao T, Kanayama N
    • Journal Title

      J Thromb Haemost

      Volume: 9(6) Pages: 1200-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Syndecan-4 prevents cardiac rupture and dysfunction after myocardial infarction2011

    • Author(s)
      Y Matsui, M Ikesue, K Danzaki, J Morimoto, M Sato, S Tanaka, T Kojima, H Tsutsui, T Uede
    • Journal Title

      Circ Res

      Volume: 108(11) Pages: 1328-1339

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Syndecan-4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cell proliferation and vascular progenitor cell mobilization.2011

    • Author(s)
      Ikesue M, Matsui Y, Ohta D, Danzaki K, Ito K, Kanayama M, Kurotaki D, Morimoto J, Kojima T, Tsutsui H, Uede T
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 31(5) Pages: 1066-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Virus-Associated Hemophagocytic Syndrome Caused by Pandemic Swine-Origin Influenza A (H1N1) in a Patient After Unrelated Bone Marrow Transplantation2011

    • Author(s)
      A Katsumi, T Nishida, M Murata, S Terakura, K Shimada, S Saito, M Kobayashi, A Kodaira, S Shibata, I Oda, T Yagi, H Kiyoi, T Matsushita, T Kojima, T Naoe
    • Journal Title

      J Clin Exp Hematopathol

      Volume: 51(1) Issue: 1 Pages: 63-65

    • DOI

      10.3960/jslrt.51.63

    • NAID

      10028239126

    • ISSN
      1346-4280, 1880-9952
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Life-threatening haemorrhage and prolonged wound healing are remarkable phenotypes manifested by complete PAI-1 deficiency in humans2011

    • Author(s)
      T Iwaki, A Tanaka, Y Miyawaki, A Suzuki, T Kobayashi, J Takamatsu, T Matsushita, K Umemura, T Urano, T Kojima, T Terao, N Kanayama
    • Journal Title

      J Thromb Haemost

      Volume: 9(6) Pages: 1200-1206

    • DOI

      10.1111/j.1538-7836.2011.04288.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524, KAKENHI-PROJECT-22590826, KAKENHI-PROJECT-22591059, KAKENHI-PROJECT-22790247
  • [Journal Article] Historical perspective and future direction of coagulation research2011

    • Author(s)
      Saito H, Matsushita T, Kojima T
    • Journal Title

      J Thromb Haemost

      Volume: Suppl 1 Pages: 352-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Venous thromboembolism and a race-specific genetic variation, protein S K196E, in Japanese2011

    • Author(s)
      Ikesue M., et al
    • Journal Title

      J Thromb Haemost

      Volume: 31 Pages: 1066-1074

    • DOI

      10.1161/atvbaha.110.217703

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117004, KAKENHI-PROJECT-21390236, KAKENHI-PROJECT-22590524
  • [Journal Article] A novel splice site mutation in intron C of PROS1 leads to markedly reduced mutant mRNA level, absence of thrombin-sensitive region, and impaired secretion and cofactor activity of mutant protein S.2010

    • Author(s)
      Okada H, Kunishima S, Hamaguchi M, Takagi A, Yamamoto K, Takamatsu J, Matsushita T, Saito H, Kojima T, Yamazaki T.
    • Journal Title

      Thrombosis Research

      Volume: 125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591148
  • [Journal Article] Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation.2010

    • Author(s)
      Miyawaki Y, Suzuki A, Fujimori Y, Takagi A, Murate T, Suzuki N, Katsumi A, Naoe T, Yamamoto K, Matsushita T, Takamatsu J, Kojima T.
    • Journal Title

      International Journal of Hematology

      Volume: 92 Pages: 405-408

    • NAID

      10026712691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591148
  • [Journal Article] Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation2010

    • Author(s)
      Y Miyawaki, A Suzuki, Y Fujimori, A Takagi, T Murate, N Suzuki, A Katsumi, T Naoe, K Yamamoto, T Matsushita, J Takamatsu, T Kojima
    • Journal Title

      Int J Hematol

      Volume: 92(2) Pages: 405-408

    • NAID

      10026712691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] A novel splice site mutation in intron C of PROS1 leads to markedly reduced mutant mRNA level, absence of thrombin-sensitive region, and impaired secretion and cofactor activity of mutant protein S.2010

    • Author(s)
      H Okada, S Kunishima, M Hamaguchi, A Takagi, K Yamamoto, J Takamatsu, T Matsushita, H Saito, T Kojima, T Yamazaki
    • Journal Title

      Thromb Res

      Volume: 125(5)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Down-regulation of PROSl gene expression by 17β-estradiol via estrogen receptor α(ERα)-Splinteraction recruiting receptor-interactingng protein140 and the corepressor-HDAC3 complex.2010

    • Author(s)
      A Suzuki, T Kojima, et al.
    • Journal Title

      J Biol Chem.

      Volume: 285 Pages: 13444-13453

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Activated protein C resistance in the Japanese population due to homozygosity for the factor V R2 haplotype2010

    • Author(s)
      H Okada, Y Toyoda, A Takagi, H Saito, T Kojima, T Yamazaki
    • Journal Title

      Int J Hematol

      Volume: 91(3) Pages: 549-550

    • NAID

      10026401575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] A novel splice site mutation in intron C of PROS1 leads to markedly reduced mutant mRNA level, absence of thrombin-sensitive region, and impaired secretion and cofactor activity of mutant protein S.2010

    • Author(s)
      Okada H, Kunishima S, Hamaguchi M, Takagi A, Yamamoto K, Takamatsu J, Matsushita T, Saito H, Kojima T, Yamazaki T.
    • Journal Title

      Thrombosis Research 125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591148
  • [Journal Article] Down-regulation of PROS1 gene expression by 17.-estradiol via estrogen receptor . (ER.)-Sp1 interaction recruiting receptor-interacting protein140 and the corepressor-HDAC3 complex.2010

    • Author(s)
      A Suzuki, N Sanda, Y Miyawaki, Y Fujimori, T Yamada, A Takagi, T Murate, H Saito, T Kojima
    • Journal Title

      J. Biol. Chem

      Volume: 285(18) Pages: 13444-13453

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation.2010

    • Author(s)
      Y Miyawaki, T Kojima, et al.
    • Journal Title

      Int J Hematol.

      Volume: 92 Pages: 405-408

    • NAID

      10026712691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] A novel splice site mutation in intron C of PROSl leads to markedly reduced mutant mRNA level, absence of thrombin-sensitive region, and impaired secretion and cofactor activity of mutant protein S.2010

    • Author(s)
      H Okada, T Kojima, et al.
    • Journal Title

      Thromb Res.

      Volume: 125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Journal Article] Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation.2010

    • Author(s)
      Miyawaki Y, Suzuki A, Fujimori Y, Takagi A, Murate T, Suzuki N, Katsumi A, Naoe T, Yamamoto K, Matsushita T, Takamatsu J, Kojima T.
    • Journal Title

      International Journal of Hematology 92

      Pages: 405-408

    • NAID

      10026712691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591148
  • [Journal Article] Stress-induced PAI-1 expression is suppressed by pitavastatin in vivo.2009

    • Author(s)
      Yamamoto K, Takeshita K, Kojima T, Takamatsu J.
    • Journal Title

      International Journal of Hematology 89

      Pages: 553-554

    • NAID

      10025161609

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591148
  • [Journal Article] A novel cholesterol absorption inhibitor, ezetimibe, decreases adipose-derived and vascular PAI-1 expression in vivo.2009

    • Author(s)
      Yamamoto K, Shibayama S, Takeshita K, Kojima T, Takamatsu J.
    • Journal Title

      Thrombosis Research 124

      Pages: 644-645

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591148
  • [Journal Article] T Murate : Implications of sphingosine kinase 1 expression level for the cellular sphingolipid rheostat: relevance as a marker for daunorubicin sensitivity of leukemia cells2008

    • Author(s)
      S Sobue, S Nemoto, M Murakami, H Ito, A Kimura, S Gao, A Furuhata, A Takagi, T Kojima, M Nakamura, M Ito, M Suzuki, Y Banno, Y Nozawa
    • Journal Title

      Int J Hematol 87(3)

      Pages: 266-275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged to Alanine scanning mutagenesis.2008

    • Author(s)
      Nakayama T, Matsushita T, Kojima T, Yamamoto K, Sadler EJ, Naoe T, Saito H.
    • Journal Title

      International Journal of Hematology 87

      Pages: 363-370

    • NAID

      10025158532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591148
  • [Journal Article] v-Src oncogene product increases sphingosine kinase 1 expression through mRNA stabilization : alteration of AU-rich element-binding proteins.2008

    • Author(s)
      S. Sobue, T. Kojima., et al.
    • Journal Title

      Oncogene. 27

      Pages: 6023-6033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Molecular Defects Associated with Antithrombin Deficiency and Dilated Cardiomyopathy in a Japanese Patient.2008

    • Author(s)
      Y. Pujimori, T. Kojima., et al.
    • Journal Title

      Inter Med. 47

      Pages: 925-931

    • NAID

      130000078680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Syndecan-4 protects against osteopontin-mediated acute hepatic injury by masking functiona1 domains of osteopontin.2008

    • Author(s)
      S. Kon, T. Kojima, et. al.
    • Journal Title

      Thromb Haemost 205

      Pages: 25-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Prognostic implication and biological roles of RhoH in acute myeloid leukaemia2008

    • Author(s)
      T Iwasaki, A Katsumi, H Kiyoi, R Tanizaki, Y Ishikawa, K Ozeki, M Kobayashi, A Abe, T Matsushita, T Watanabe, M Amano, T Kojima, K Kaibuchi, T Naoe
    • Journal Title

      Eur J Haematol 81(6)

      Pages: 454-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Prognostic implication and biological roles of RhoH in acute myeloid leukaemia.2008

    • Author(s)
      T. Iwasaki, T. Kojima, et al.
    • Journal Title

      Eur J Haematol. 81

      Pages: 454-460

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] v-Src oncogene product increases sphingosine kinase 1 expression through mRNA stabilization: alteration of AU-rich element-binding proteins2008

    • Author(s)
      S Sobue, M Murakami, Y Banno, H Ito, A Kimura, S Gao, A Furuhata, A Takagi, T Kojima, M Suzuki, Y Nozawa, T Murate
    • Journal Title

      Oncogene 27(46)

      Pages: 6023-6033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Molecular Defects Associated with Antithrombin Deficiency and Dilated Cardiomyopathy in a Japanese Patient2008

    • Author(s)
      Y Fujimori, H Okimatsu, T Kashiwagi, N Sanda, K Okumura, A Takagi, K Nagata, T Murate, A Uchida, K Node, H Saito and T Kojima
    • Journal Title

      Inter Med. 47(10)

      Pages: 925-931

    • NAID

      130000078680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged-to-alanine-scanning mutagenesis2008

    • Author(s)
      T Nakayama, T Matsushita, K Yamamoto, N Mutsuga, T Kojima, A Katsumi, N Nakao, JE Sadler, T Naoe, H Saito
    • Journal Title

      Int J Hematol 87(4)

      Pages: 363-370

    • NAID

      10025158532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Mutational analysis of SOS1 in acute myeloid eukemia2008

    • Author(s)
      Tanizaki, A Katsumi, H Kiyoi, S unishima, T Iwasaki, Y Ishikawa, M obayashi, A Abe, T Matsushita, T Watanabe, Kojima, K Kaibuchi, S Kojima, T Naoe
    • Journal Title

      Int J Hematol 88(4)

      Pages: 460-462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Skewed X chromosome inactivation in fratemal female twins results in moderately severe and mild haemophilia B.2008

    • Author(s)
      K. Okumura, T. Kojima, et al.
    • Journal Title

      Haemophilia 14

      Pages: 1088-1093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged-to-alanine-scanning mutagenesis.2008

    • Author(s)
      T. Nakayama, T. Kojima, et al.
    • Journal Title

      Int J Hematol. 87

      Pages: 363-370

    • NAID

      10025158532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] A neonate with homozygous protein C deficiency with a homozygous Argl78Trp mutation.2008

    • Author(s)
      F. Ozlu, T. Kojima, et al.
    • Journal Title

      J Pediatr Hematol Oncol 30

      Pages: 608-611

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] A neonate with homozygous protein C deficiency with a homozygous Arg178Trp mutation2008

    • Author(s)
      F Ozlu, M Kyotani, E Taskin, K Ozcan, T Kojima, T Matsushita, H Yapicioglu, A Takagi, I Sasmaz, M Satar, and N Narli
    • Journal Title

      J Pediatr Hematol Oncol 30

      Pages: 608-611

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] L1503R is a member of group I mutation and has dominant-negative effect on secretion of full-length VWF multimers: an analysis of two patients with type 2A von Willebrand disease.2008

    • Author(s)
      T Kashiwagi, T Mstsushita, Y Ito, K Hirashima, N Sanda, Y Fujimori, T Yamada, K Okumura, A Takagi, T Murate, A Katsumi, J Takamatsu, K Yamamoto, T Naoe, T Kojima
    • Journal Title

      Haemophilia 14(3)

      Pages: 556-563

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Skewed X chromosome inactivation in fraternal female twins results in moderately severe and mild haemophilia B2008

    • Author(s)
      K Okumura, Y Fujimori, A Takagi, T Murate, M Ozeki, K Yamamoto, A Katsumi, T Matsushita, T Naoe, and T Kojima
    • Journal Title

      Haemophilia 14(5)

      Pages: 1088-1093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Mufational analysis of SOS1 in acute myeloid leukemia.2008

    • Author(s)
      R. Tanizaki, T. Kojima, et al.
    • Journal Title

      Int J Hematol. 88

      Pages: 460-462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Implications of sphingosine kinase 1 expression level for the cellular sphingolipid rheosfat : relevance as a marker for daunonibicin sensitivity of leukemia cells.2008

    • Author(s)
      S. Sobue, T. Kojima., et al.
    • Journal Title

      Int J Hematol 87

      Pages: 266-275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Molecular basis of antithrombin deficiency in four Japanese patients with antithrombin gene abnormalities including two novel mutations.2007

    • Author(s)
      M. Kyotani, T. Kojima, et. al.
    • Journal Title

      Am J Hemato1 82

      Pages: 702-705

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] An Sp1 binding site mutation of the PROSl promoter in a patient with protein S deficiency.2007

    • Author(s)
      N. Sanda, T. Kojima, et. al.
    • Journal Title

      Br J Haematol 138

      Pages: 663-665

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] An Sp1 binding site mutation of the PROS1 promoter in a patient with protein S deficiency2007

    • Author(s)
      N Sanda, Y Fujimori, T Kashiwagi, A Takagi, T Murate, E Mizutani, T Matsushita, T Naoe, T Kojima
    • Journal Title

      Br J Haematol 138(5)

      Pages: 663-665

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] A large deletion of the PROSl gene in a deep vein thrombosis patient with protein S deficiency.2007

    • Author(s)
      T. Yin T. Kojima, et. al.
    • Journal Title

      Thromb Haemost 98

      Pages: 783-789

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Wilms' tumor 1 message and protein expression in bone marrow failure syndrome and acute leukemia2007

    • Author(s)
      T Iwasaki, C Sugisaki, K Nagata, K Takagi, A Takagi, T Kojima, M Ito, S Nakamura, T Naoe, T Murate
    • Journal Title

      Pathol Int 57(10)

      Pages: 645-651

    • NAID

      10021233832

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Pitavastatin attenuates the upregulation of tissue factor in restraint-stressed mice2007

    • Author(s)
      Yamamoto, K, Kojima, T. Takeshita, K. Matsushita, T. Takamatsu, J
    • Journal Title

      Thrombosis Research Volume120, number1

      Pages: 143-144

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591053
  • [Journal Article] RET signaling-induced SPHK1 gene expression plays a role in both GDNF-induced differentiation and MEN2-type oncogenesis2007

    • Author(s)
      Murakami, M Ichihara, S Sobue, R Kikuchi, H Ito, A Kimura, T Iwasaki, A Takagi, T Kojima, M Takahashi, M Suzuki, Y Banno, Y Nozawa, T Murate1
    • Journal Title

      J Neurochem 102(5)

      Pages: 1585-1594

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Mechanism of vitamin D3-induced transcription of phospholipase Dl in HaCat human keratinocytes.2007

    • Author(s)
      R. Kikuchi, T. Kojima, et. al.
    • Journal Title

      FEBS Lett 581

      Pages: 1800-1804

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Pitavastatin attenuates the upregulation of tissue factor in restraint-stressed mice.2007

    • Author(s)
      Yamamoto K, Kojima T, Takeshita K, Matsushita T, Takamatsu J.
    • Journal Title

      Thrombosis Research 120

      Pages: 143-144

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591053
  • [Journal Article] A large deletion of the PROS1 gene in a deep vein thrombosis patient with protein S deficiency2007

    • Author(s)
      T Yin, S Takeshita, Y Sato, T Sakata, Y Shin, S Honda, T Kawasaki, H Tsuji, T Kojima, S Madoiwa, Y Sakata, M Murata, Y Ikeda, T Miyata
    • Journal Title

      Thromb Haemost 98(4)

      Pages: 783-789

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Mechanism of vitamin D3-induced transcription of phospholipase D1 in HaCat human keratinocytes2007

    • Author(s)
      R Kikuchi, S Sobue, M Murakami, H Ito, A Kimura, T Iwasaki, S Shibayama, A Takagi, T Kojima, M Suzuki, Y Banno, Y Nozawa, T Murate
    • Journal Title

      FEBS Lett 581(9)

      Pages: 1800-1804

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] RET signaling-induced SPHKl gene expression plays a role in both GDNF-induced differentiation and MEN2-type oncogenesis2007

    • Author(s)
      M. Murakami, T. Kojima, et. al.
    • Journal Title

      J Neurochem 102

      Pages: 1585-1594

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Molecular basis of antithrombin deficiency in four Japanese patients with antithrombin gene abnormalities including two novel mutations2007

    • Author(s)
      M Kyotani, K Okumura, A Takagi, T Murate, K Yamamoto, T Matsushita, M Sugimura, N Kanayama, T Kobayashi, H Saito, T Kojima
    • Journal Title

      Am J Hematol 82(2)

      Pages: 702-705

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Wilms' tumor 1 message and protein expression in bone marrow failure syndrome and acute leukemia.2007

    • Author(s)
      T. Iwasaki, T. Kojima, et. al.
    • Journal Title

      Pathol Int 57

      Pages: 645-651

    • NAID

      10021233832

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Journal Article] Obesity enhances the induction of plasminogen activator inhibitor-1 by restraint stress : a possible mechanism of stress-induced renal fibrin deposition in obese mice.2005

    • Author(s)
      Yamamoto K, Kojima T, Adachi T, Hayashi M, Matsushita T, Takamatsu J, Loskutoff DJ, Saito H.
    • Journal Title

      Journal of Thrombosis and Haemostasis 3巻・7号

      Pages: 1495-1502

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590934
  • [Journal Article] Transcription factor specificity protein 1 (Sp1) is the main regulator of nerve growth factor-induced sphingosine kinase 1 gene expression of the rat pheochromocytoma cell line, PC12.2005

    • Author(s)
      Sobue S, Hagiwara K, Banno Y, Tamiya-Koizumt K, Suzuki M, Takagi A, Kojima T, Asano H, Nozawa Y, Murate T.
    • Journal Title

      J Neurochem. 95(4)

      Pages: 940-949

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590453
  • [Journal Article] Obesity enhances the induction of plasminogen activator inhibitor-1 by restraint stress : a possible mechanism of stress-induced renal fibrin deposition. In obese mice.2005

    • Author(s)
      Yamamoto K, Kojima T, Adachi T, Hayashi M, Matsushita T, Takamatsu J, Loskutoff DJ, Saito H.
    • Journal Title

      Journal of Thrombosis and Haemostasis Volume 3 - number 7

      Pages: 1495-1502

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590934
  • [Journal Article] AT/D併用によるエンドトキシン誘発臓器傷害の改善効果-Antithrombin/danaparoid sodiumの抗凝固薬としての位置付け2004

    • Author(s)
      小嶋哲人
    • Journal Title

      日本集中治療医学会雑誌 11(13)

      Pages: 174-176

    • Data Source
      KAKENHI-PROJECT-15591000
  • [Patent] 血栓症のリスク検査法2013

    • Inventor(s)
      高木明、小嶋哲人、高木夕希、村田萌
    • Industrial Property Rights Holder
      国立大学法人名古屋大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-182541
    • Filing Date
      2013-09-03
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Patent] 凝固因子として作用する異常トロンビンのためのトロンビン不活化動態測定方法2013

    • Inventor(s)
      高木 明、小嶋 哲人、松下 正
    • Industrial Property Rights Holder
      国立大学法人名古屋大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-04-01
    • Acquisition Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Patent] 血栓症のリスク検査法2013

    • Inventor(s)
      高木明、小嶋哲人、高木夕希、村田萌
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-07-17
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Patent] 凝固因子として作用する異常トロンビンのためのトロンビン不活化動態測定方法及び試験方法、並びに、ポリヌクレオチド2010

    • Inventor(s)
      高木明, 小嶋哲人, 松下正
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Number
      2010-289686
    • Filing Date
      2010-12-27
    • Data Source
      KAKENHI-PROJECT-22659114
  • [Patent] 凝固因子として作用する異常トロンビンのためのトロンビン不活化動態測定方法及び試験方法、並びに、ポリヌクレオチド2010

    • Inventor(s)
      高木明, 小嶋哲人, 松下正
    • Industrial Property Rights Holder
      国立大学法人名古屋大学
    • Industrial Property Number
      2010-289686
    • Filing Date
      2010-12-27
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Patent] 凝固因子として作用する異常トロンビンのためのトロンビン不活化動態測定方法及び試験方法、並びに、ポリヌクレオチド2010

    • Inventor(s)
      高木 明、小嶋 哲人、松下 正
    • Industrial Property Rights Holder
      国立大学法人名古屋大学
    • Filing Date
      2010-12-27
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Patent] 血液凝固第VII 因子プロモーターの活性化剤及びその利用2007

    • Inventor(s)
      本多隆、高松純樹、豊田秀徳、山本晃士、後藤秀実、小嶋哲人
    • Industrial Property Rights Holder
      国立大学法人名古屋大学
    • Filing Date
      2007-08-27
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Patent] 血液凝固第VII因子プロモーターの活性化剤及びその利用2007

    • Inventor(s)
      本田 隆 小嶋哲人, ら
    • Industrial Property Rights Holder
      国立大学法人名古屋大学
    • Industrial Property Number
      2007-220451
    • Filing Date
      2007-08-27
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] Genetic Abnormalities of Japanese Patient with Symptomatic- and Asymptomatic-dysfibrinogenemia2019

    • Author(s)
      Y. Hattori, S. Tamura, N. Suzuki, M. Kakihara, S. Suzuki, K. Odaira, M. Tokoro, F. Hayakawa, S. Okamoto, T. Kanematsu, T. Matsushita, T. Kojima
    • Organizer
      ISTH2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] 先天性凝固異常症の遺伝子解析 「解析のStrategyとPitfall」2019

    • Author(s)
      田村彰吾、高木明、早川文彦、小嶋哲人
    • Organizer
      第20回日本検査血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] 特発性血小板減少性紫斑病の病勢に対し,サイトメガロウイルス再活性化の関与が疑わ れた 2 例2019

    • Author(s)
      兼松 毅,鈴木 伸明,岡本 修一,鈴木 敦夫,川上 萌, 三田 直美,田村 彰吾,小嶋 哲人,清井 仁,松下 正
    • Organizer
      第41回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] ト ロ ン ビ ン Na binding regionの ミ ス セ ン ス 変異は 多く が ア ン チ ト ロ ン ビ ン 抵抗性を 示す が 、 凝固活性も 低下す る2019

    • Author(s)
      田村彰吾、 川上萌、 勝見章、 高木明、 早川文彦 、 小嶋哲人
    • Organizer
      ト ロ ン ビ ン Na binding regionの ミ ス セ ン ス 変異は 多く が ア ン チ ト ロ ン ビ ン 抵抗性を 示す が 、 凝固活性も 低下す る
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] int1h-1 を介した組換えではあるが Inv1 ではなく F8 イントロン 1 での複雑な大規模欠 失挿入変異による重症血友病 A2019

    • Author(s)
      所 真昼,田村 彰吾,鈴木 伸明,垣原美紗樹,服部 有那, 大平 晃也,鈴木 幸子,高木 明,早川 文彦,岡本 修一,兼松 毅, 松下 正,小嶋 哲人
    • Organizer
      第41回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] An Inv22-like F8 Inverted Disruption in Severe Hemophilia a Brothers Possibly Occurring from Template Switching between Sister Chromatids2019

    • Author(s)
      M. Kakihara, S. Tamura, M. Tokoro, K. Odaira, Y. Hattori, S. Suzuki, F. Hayakawa, M. Ogawa, T. Kanematsu, N. Suzuki, T. Matsushita, T. Kojima
    • Organizer
      ISTH2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] F9 サイレント変異 c.87A > G(p.Thr29 =)に起因するスプライシング異常の分子病態解析2019

    • Author(s)
      大平 晃也,田村 彰吾,所 真昼,垣原美紗樹,服部 有那, 鈴木 幸子,高木 明,早川 文彦,岡本 修一,兼松 毅,鈴木 伸明, 松下 正,小嶋 哲人
    • Organizer
      第41回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] プロトロンビン R593L マウスの作製と解析2019

    • Author(s)
      鈴木 伸明,鈴木 敦夫,鈴木 幸子,田村 彰吾,高木 明, 小嶋 哲人,松下 正
    • Organizer
      第41回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] F9 c.87A>G is a Double-faced Deleterious Mutation which Causes a Synonymous and Inframed-mutant FIX due to an Aberrant mRNA Splicing2019

    • Author(s)
      K. Odaira, S. Tamura, N. Suzuki, M. Kakihara, Y. Hattori, M. Tokoro, S. Suzuki, A. Takagi, A. Katsumi, F. Hayakawa, S. Okamoto, A. Suzuki, T. Kanematsu, T. Matsushita, T. Kojima
    • Organizer
      ISTH2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] 新規伸長型変異を認めた先天性血液凝固第 XI 因子欠乏症の 1 例2019

    • Author(s)
      早川 友梨,田村 彰吾,鈴木 伸明,大平 晃也,垣原美紗樹, 服部 有那,所 真昼,河島 史華,鈴木 幸子,早川 文彦,高木 明, 岡本 修一,兼松 毅,松下 正,小嶋 哲人
    • Organizer
      第41回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] 産科関連静脈血栓症における血栓性素因検索 -名古屋大学医学部附属病院における症例 第 2 報-2019

    • Author(s)
      鈴木 幸子,垣原美紗樹,服部 有那,大平 晃也,所 真昼, 河島 史華,早川 友梨,岡本 修一,兼松 毅,中野 知子,今井 健史, 牛田 貴文,森山 佳則,小谷 友美,鈴木 伸明,田村 彰吾,早川 文彦, 小嶋 哲人,松下 正
    • Organizer
      第41回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] A Complex F8 Rearrangement Associated with Template Switching and int1h-related Homologous Recombination in a Patient with Severe Hemophilia A2019

    • Author(s)
      M. Tokoro, S. Tamura, N. Suzuki, M. Kakihara, Y. Hattori, K. Odaira, S. Suzuki, A. Takagi, F. Hayakawa, S. Okamoto, T. Kanematsu, T. Matsushita, T. Kojima
    • Organizer
      ISTH2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] Molecular genetic analysis of dysfibrinogenemia including novel mutations with thrombosis2018

    • Author(s)
      Yuna Hattori, Shogo Tamura, Misaki Kakihara, Sachiko Suzuki, Koya Odaira, Mahiru Tokoro, Humihiko Hayakawa, Tsuyoshi Kanemetsu, Nobuaki Suzuki, Tadashi Matsushita, Tetsuhito Kojima
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] 血漿検体測定を 目指し た ア ン チ ト ロ ン ビ ン 抵抗性凝固第X因子検出法の 構築2018

    • Author(s)
      田村彰吾、 藤岡亮也、 服部有那、 垣原美紗樹、 鈴木幸子、 高木夕希、 高木明、 小嶋哲人
    • Organizer
      第19回日本検査血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] Haploid origin of unusual Inv22 X-chromosome carrying wild-type telomere region in severe hemophilia A patients2018

    • Author(s)
      Misaki Kakihara, Shogo Tamura, Yuna Hattori, Sachiko Suzuki, Koya Odaira, Mahiru Tokoro, Takeshi Kanematsu, Nobuaki Suzuki, Tadashi Matsushita, Tetsuhito Kojima
    • Organizer
      APSTH2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] ス プ ラ イ シ ン グ 異常を 引き 起こ す 血液凝固第IX遺伝子サ イ レ ン ト 変異・ 血友病Bの 分子病態解析2018

    • Author(s)
      大平晃也、 田村彰吾、 坂根寛人、 所 真昼、 垣原美紗樹、 服部有那、 橋本恵梨華、 鈴木幸子、 高木夕希、 高木明、 兼松毅、 岸本磨由子、 鈴 木伸明、 松下正、 小嶋哲人
    • Organizer
      第40回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] Many of the prothrombin mutations in the sodium-binding region cause an antithrombin- resistance phenotype2018

    • Author(s)
      Shogo Tamura, Moe Murata-Kawakami, Yuki Takagi, Sachiko Suzuki, Akira Katsumi, Akira Takagi, Tetsuhito Kojima
    • Organizer
      第40回日本血栓止血学会学術集会学術推進委員会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08967
  • [Presentation] 血液凝固第V因子欠乏症を 合併す る 血友病A症例: 第2 報・ 凝血学的評価2018

    • Author(s)
      鈴木幸子、 髙木夕希、 坂根寛人、 橋本恵梨華、 垣原美紗樹、 服部有那、 大平晃也、 所真昼、 田村彰吾、 高木明、 鈴木敦夫、 鈴木伸明、 松下 正、 山崎鶴夫、 小嶋哲人
    • Organizer
      第40回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] 脳梗塞を 発症し た フ ィ ブ リ ノ ゲ ン 異常症の 分子病態機能解析2018

    • Author(s)
      服部有那、 垣原美紗樹、 高木夕希、 鈴木幸子、 橋本恵梨華、 坂根寛人、 田村彰吾、 高木明、 松下正、 小嶋哲人
    • Organizer
      第40回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] Antithrombin resistance: a unique inherited thrombophilia2018

    • Author(s)
      Tetsuhito Kojima
    • Organizer
      The 10th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] 鈴木敦夫、 鈴木伸明、 兼松毅、 岸本磨由子、 田村彰吾、 高木明、 川上萌、 梶浦容子、 小嶋哲人、 松下正2018

    • Author(s)
      鈴木敦夫、 鈴木伸明、 兼松毅、 岸本磨由子、 田村彰吾、 高木明、 川上萌、 梶浦容子、 小嶋哲人、 松下正
    • Organizer
      第40回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] Functional analysis of a variant fibrinogen from dysfibrinogenemia patient with cerebral infarction2018

    • Author(s)
      Hattori Y, Takagi Y, Kakihara M, Suzuki S, Odaira K, Tokoro M, Tamura S, Suzuki N, Matushita T, Kojima T
    • Organizer
      APSTH2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] F8 Inv22を 含む 複雑な 変異を 同定し た 重症血友病A症例の 遺伝学的変異ア レ ル 由来の 検索2018

    • Author(s)
      垣原美紗樹、 田村彰吾、 服部有那、 高木夕希、 鈴木幸子、 橋本恵梨華、 坂根寛人、 大平晃也、 所真昼、 高木明、 小川実加、 兼松毅、 鈴木伸 明、 松下正、 小嶋哲人
    • Organizer
      第40回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] 血友病Aに お い て 関節症の 進行抑制に は 出血抑制よ り も 高い FVIII活性が 必要で あ る2018

    • Author(s)
      鈴木伸明、 鈴木敦夫、 高橋伸典、 田村彰吾、 兼松毅、 高木明、 小嶋俊久、 清井仁、 小嶋哲人、 石黒直樹、 松下正
    • Organizer
      第40回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] Peri-arteriolar megakaryopoietic microenvironment via reciprocal CLEC-2/PDPN axis in mouse bone marrow2018

    • Author(s)
      Shogo Tamura, Katsue Suzuki-Inoue, Yukio Ozaki, Tetsuhito Kojima
    • Organizer
      第80回日本血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19910
  • [Presentation] 血液凝固第V因子欠乏症を合併する血友病 A 症例:第2報・凝血学的評価2018

    • Author(s)
      鈴木幸子,高木夕希,坂根寛人,橋本恵梨華,垣原美紗樹,服部有那,大平晃也,所真昼,田村彰吾,高木明,鈴木敦夫,鈴木伸明,松下正,山崎鶴夫,小嶋哲人
    • Organizer
      第40回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] 血漿検体測定を目指したアンチトロンビン抵抗性凝固第X因子検出法の構築2018

    • Author(s)
      田村彰吾,高木明,藤岡亮也,服部有那,垣原美紗樹,高木夕希,鈴木幸子,高木夕希,小嶋哲人
    • Organizer
      第19回日本検査血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] F8 Inv22を含む複雑な変異を同定した重症血友病A症例の遺伝学的変異アレル由来の検索2018

    • Author(s)
      垣原美紗樹,田村彰吾,服部有那,高木夕希,鈴木幸子,橋本恵梨華,坂根寛人,大平晃也,所真昼,高木明,小川実加,兼松毅,鈴木伸明,松下正,小嶋哲人
    • Organizer
      第40回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] Functional analysis of a variant fibrinogen from dysfibrinogenemia patient with cerebral2018

    • Author(s)
      Yuna Hattori, Takagi Yuki, Misaki Kakihara, Sachiko Suzuki, Koya Odaira, Mahiru Tokoro, Shogo Tamura, Tsuyoshi Kanemetsu, Nobuaki Suzuki, Tadashi Matsushita, Tetsuhito Kojima
    • Organizer
      The 10th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] Antithrombin resisitance 検査法の改良:Bovine FXa/Va prothrombin activator システムの構築と血液凝固分析装置適応条件の検討2018

    • Author(s)
      田村彰吾,川上萌,垣原美紗樹,服部有那,鈴木幸子,高木夕希,高木明,小嶋哲人
    • Organizer
      第12 回日本血栓止血学会学術標準化委員会(SSC)シンポジウム
    • Data Source
      KAKENHI-PROJECT-16K08967
  • [Presentation] 血漿検体測定を目指したアンチトロンビン抵抗性凝固第X因子検出法の構築2018

    • Author(s)
      田村彰吾、高木 明、藤岡亮也、服部有那、垣原美紗樹、鈴木幸子、高木夕希、小嶋哲人
    • Organizer
      第19回日本検査血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K08967
  • [Presentation] Peri-arteriolar megakaryopoieticmicroenviroment via reciprocal CLEC-2/PDPN axis mouse bone marrow2018

    • Author(s)
      Shogo Tamura, Katsue Suzuki-Inoue, Yukio Ozaki, Tetsuhito Kojima
    • Organizer
      第80回日本血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] Haploid origin of unusual Inv22 X-chromosome carrying wild-type telomere region in severe hemophilia A patients2018

    • Author(s)
      Misaki Kakihara, Shogo Tamura, Yuna Hattori, Sachiko Suzuki, Koya Odaira, Mahiru Tokoro, Takeshi Kanematsu, Nobuaki Suzuki, Tadashi Matsushita, Tetsuhito Kojima
    • Organizer
      The 10th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] スプライシング異常を引き起こす血液凝固第IX遺伝子サイレント変異・血友病B分子病態2018

    • Author(s)
      大平晃也,田村彰吾,坂根寛人,所真昼,垣原美紗樹,服部有那,橋本恵梨華,鈴木幸子,高木夕希,高木明,兼松毅,岸本麻由子,鈴木伸明,松下正,小嶋哲人
    • Organizer
      第40回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] 特発生血栓 : アンチトロンビン抵抗性の診断-凝検査法を中心に-2018

    • Author(s)
      高木明,田村彰吾,小嶋哲人
    • Organizer
      第19回日本検査血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] 脳梗塞を発症したフィブリノケゲン異常症の分子病態機能解析2018

    • Author(s)
      服部有那,垣原美紗樹,高木夕希,鈴木幸子,橋本恵梨華,坂根寛人,大平晃也,所真昼,田村彰吾,高木明,鈴木伸明,松下正,小嶋哲人
    • Organizer
      第40回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] アンチトロンビン抵抗性の診断 -検査法を中心に-2018

    • Author(s)
      高木明、田村彰吾、小嶋哲人
    • Organizer
      第19回日本検査血液学会学術集会シンポジウム1 特発性血栓症
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08967
  • [Presentation] アンチトロンビン抵抗性凝固第 Xa 因子検出法の開発2017

    • Author(s)
      藤岡亮也、中田悠紀子、坂根寛人、橋本恵梨華、河村奈美、槇山愛弓、鈴木幸子、高木夕希、田村彰吾、高木明、小嶋哲人
    • Organizer
      第39回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K08967
  • [Presentation] Thrombin generation assay CANNOT identify antithrombin resistance during anticoagulant therapy2017

    • Author(s)
      Yuki Takagi, Sachiko Suzuki, Nami Kawamura, Ayumi Makiyama, Hiroto Sakane, Erika Hashimoto, Akiya Fujioka, Shogo Tamura, Akira Takagi, Valentina Djordjevic, Tetsuhito Kojima
    • Organizer
      XXVI Congress of International Society on Thrombosis and Haemostasis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] Assessment of F9 mutation associated with inhibitor development in Japanese hemophilia B patients2017

    • Author(s)
      Hiroto Sakane, Shogo Tamura, Erika Hashimoto, Akiya Fujioka, Ayumi Makiyama, Nami Kawamura, Sachiko Suzuki, Yuki Takagi, Tsuyoshi Kanematsu, Mayuko Kishimoto, Mika Ogawa, Nobuaki Suzuki, Tadashi Matsushita, Hiroshi Yada, Midori Shima, Tetsuhito Kojima
    • Organizer
      XXVI Congress of International Society on Thrombosis and Haemostasis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] アンチトロンビン抵抗性はトロンビン生成試験(TGA)により検出可能か2017

    • Author(s)
      高木夕希、鈴木幸子、河村奈美、槇山愛弓、坂根寛人、橋本恵梨華、藤岡亮也、田村彰吾、高木明、小嶋哲人
    • Organizer
      第39回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K08967
  • [Presentation] Unusual Genomic Rearrangement combined with Inv22 and wild-type X-chromosome in severe hemophilia A patients2017

    • Author(s)
      Shogo Tamura, Misaki Kakihara, Yuna Hattori, Erika Hashimoto, Hiroto Sakane, Yuki Takagi, Mika Ogawa, Takeshi Kanematsu, Nobuaki Suzuki, Akira Takagi, Tadashi Matsushita, Tetsuhito kojima
    • Organizer
      XXVI Congress of International Society on Thrombosis and Haemostasis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] Thrombin generation assay CANNOT identify antithrombin resistance during anticoagulant therapy2017

    • Author(s)
      Yuki Takagi, Sachiko Suzuki, Nami Kawamura Ayumi Makiyama, Hiroto Sakane, Erika Hashimoto, Akiya Fujioka, Shogo Tamura, Akira Takagi, Tetsuhito Kojima
    • Organizer
      XXVI Congress of International Society on Thrombosis and Haemostasis,
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08967
  • [Presentation] Compound heterozygosity for mutations in ITGA2B including a novel p.Cys198Ser in Glanzmann Thrombasthenia2017

    • Author(s)
      Erika Hashimoto, Shinji Kunishima, Yuki Takagi, Sachiko Suzuki, Ayumi Makiyama, Hiroto Sakane, Akiya Fujioka, Takahiro Uehara, Shogo Tamura, Akira Takagi, Tetsuhito kojima
    • Organizer
      XXVI Congress of International Society on Thrombosis and Haemostasis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] 新しい遺伝性血栓性素因:アンチトロンビン・レジスタンス2017

    • Author(s)
      小嶋哲人
    • Organizer
      第59回日本小児血液・がん学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] Molecular basis of F8 gene abnormality in hemophilia A patients in Nagoya2016

    • Author(s)
      Nami KAWAMURA, Ayumi MAKIYAMA, Yuki TAKAGI, Erika HASHIMOTO, Hiroto SAKANE, Akiya FUJIOKA, Shogo TAMURA, Akira TAKAGI, Nobuaki SUZUKI, Tadashi MATSUSHITA, Tetsuhito KOJIMA
    • Organizer
      The 9th Congress of Asia Pacific Society of Thrombosis and Hemostasis (APSTH)
    • Place of Presentation
      Taipei
    • Year and Date
      2016-10-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] プロテインC欠乏症51家系のPROC遺伝子解析2016

    • Author(s)
      槇山愛弓、高木夕希、河村奈美、橋本恵梨華、田村彰吾、高木明、岸本磨由子、鈴木伸明、松下正、小嶋哲人
    • Organizer
      第17回日本検査血液検査血液学会学術集会
    • Place of Presentation
      博多
    • Year and Date
      2016-08-06
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] A NOVEL LARGE DELETION FOUND IN A JAPANESE FAMILY WITH ANTITHROMBIN DEFICIENCY2016

    • Author(s)
      Erika HASHIMOTO, Yuki TAKAGI, Nami KAWAMURA, Ayumi MAKIYAMA, Hiroto SAKANE, Akiya FUJIOKA, Shogo TAMURA, Akira TAKAGI, Yoshifumi FUKUSHIMA, Makoto KANEKO, Tetsuhito KOJIMA
    • Organizer
      The 9th Congress of Asia Pacific Society of Thrombosis and Hemostasis (APSTH)
    • Place of Presentation
      Taipei
    • Year and Date
      2016-10-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] プロトロンビンArg596ミスセンス変異がトロンビンのトロンボモジュリン結合能に及ぼす影響2016

    • Author(s)
      高木夕希, 河村奈美, 槇山愛弓, 橋本恵梨華, 田村彰吾, 高木明, 小嶋哲人
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K08967
  • [Presentation] 低フィブリノゲン血症3症例の遺伝子解析2016

    • Author(s)
      高木夕希、河村奈美、槇山愛弓、橋本恵梨華、安藤裕実、加藤衣央、田村彰吾、高木明、小嶋哲人
    • Organizer
      第38回日本血栓止血学会学術集会
    • Place of Presentation
      奈良
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] Prothrombin missense mutations at 596Arg reduced the affinity of mutant thrombin to thrombomodulin controlled by Na+ concentration.2016

    • Author(s)
      Yuki Takagi, Nami Kawamura, Ayumi Makiyama, Erika Hashimoto, Shogo Tamura, Akira Takagi, Tetsuhito Kojima
    • Organizer
      XXIX International Symposium on Technical Innovations in Laboratory Hematology (ISLH)
    • Place of Presentation
      Milano, Italy
    • Year and Date
      2016-05-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09825
  • [Presentation] Prothrombin missense mutations at 596Arg reduced the affinity of mutant thrombin to thrombomodulin controlled by Na+ concentration2016

    • Author(s)
      Yuki Takagi, Nami Kawamura, Ayumi Makiyama, Erika Hashimoto, Shogo Tamura, Akira Takagi, Tetsuhito Kojima
    • Organizer
      XXIX International Symposium on Technical Innovations in Laboratory Hematology
    • Place of Presentation
      Milano
    • Year and Date
      2016-05-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08967
  • [Presentation] Analysis of prothrombin mutants in NA+ binding domain as a potential candidate conveying antithrombin resistance2015

    • Author(s)
      Moe Murata, Naoki Mizutani, Yuki Takagi, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Tetsuhito Kojima
    • Organizer
      XXV Congress of International Society on Thrombosis and Haemostasis
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2015-06-20
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] Practical laboratory assay to detect abnormal prothrombin conveying thrombomodulin resistance2015

    • Author(s)
      高木夕希、水谷直貴、村田萌、小塚敏弘、中田悠紀子、長谷部瞭、河村奈美、槇山愛弓、橋本恵梨華、高木明、小嶋哲人高木夕希、水谷直貴、村田萌、小塚敏弘、中田悠紀子、長谷部瞭、河村奈美、槇山愛弓、橋本恵梨華、高木明、小嶋哲人
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] アンチトロンビン抵抗性検出検査法の自動凝固検査機器への最適化 Part 22015

    • Author(s)
      村田 萌、水谷直貴、高木夕希、長谷部瞭、小塚敏弘、中田悠紀子、高木 明、松下 正、小嶋哲人
    • Organizer
      第16回日本検査血液検査血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-07-11
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] Investigation of molecular mechanisms of PS mRNA up-regulation by progestin isoforms in HepG2 cells.2015

    • Author(s)
      小塚敏弘、長谷部瞭、中田悠紀子、槇山愛弓、河村奈美、中村友紀、高木夕希、村田萌、水谷直貴、高木明、小嶋哲人
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] Antidotes to dabigatran and anti-Xa anticoagulants2015

    • Author(s)
      小嶋哲人
    • Organizer
      第37回日本血栓止血学会学術集会
    • Place of Presentation
      甲府
    • Year and Date
      2015-05-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] 先天性アンチトロンビン欠乏症8症例SERPINC1遺伝子解析2015

    • Author(s)
      中田悠紀子、小塚敏弘、長谷部瞭、高木夕希、村田萌、上牧務、松尾真稔、高木明、松下正、小嶋哲人
    • Organizer
      第16回日本検査血液検査血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-07-11
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] ロトロンビン変異による新たなアンチトロンビン抵抗性変異の候補解析2015

    • Author(s)
      村田萌、水谷直貴、高木夕希、長谷部瞭、小塚敏弘、中田悠紀子、槇山愛弓、河村奈美、橋本恵梨華、高木明、松下正、小嶋哲人
    • Organizer
      第37回日本血栓止血学会学術集会
    • Place of Presentation
      甲府
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] 深部静脈血栓症で発症しアンチトロンビン抵抗性を示した本邦初 Prothrombin Belgrade 変異の一家系2015

    • Author(s)
      岸本磨由子、鈴木伸明、村田萌、小川実加、兼松毅、高木明、小嶋哲人、松下正
    • Organizer
      第37回日本血栓止血学会学術集会
    • Place of Presentation
      甲府
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] A case of severe hemophilia B associated with a large insertion of SVA RETROTRANSPOSON in the coagulation factor IX gene.2015

    • Author(s)
      Naoki Mizutani, Yuki Nakamura, Moe Murata, Yuki Takagi, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Jun-ichi Kitazawa, Midori Shima, Tetsuhito Kojima
    • Organizer
      XXV Congress of International Society on Thrombosis and Haemostasis
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2015-06-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] Analysis of prothrombin mutants in NA+ binding domain as a potential candidate conveying antithrombin resistance.2015

    • Author(s)
      Moe Murata, Naoki Mizutani, Yuki Takagi, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Tetsuhito Kojima
    • Organizer
      XXV Congress of International Society on Thrombosis and Haemostasis
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2015-06-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] Analysis of prothrombin missense mutants at 596ARG by single nucleotide substitution for anticoagulant system.2015

    • Author(s)
      Yuki Takagi, Moe Murata, Yuki Nakamura, Toshihiro Kozuka, Yukiko Nakata, Ryo Hasebe, Akira Takagi, Tetsuhito Kojima
    • Organizer
      XXV Congress of International Society on Thrombosis and Haemostasis
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2015-06-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] 深部静脈血栓症で発症したアンチトロンビンレジスタンス症例の抗凝固療法2015

    • Author(s)
      岸本磨由子、鈴木伸明、村田萌、小川実加、兼松毅、高木明、小嶋哲人、松下正
    • Organizer
      第16回日本検査血液検査血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-07-11
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] プロトロンビン変異による新たなアンチトロンビン抵抗性変異の候補解析2015

    • Author(s)
      村田 萌、水谷直貴、高木夕希、長谷部瞭、小塚敏弘、中田悠紀子、槇山愛弓、河村奈美、橋本恵梨華、高木 明、松下 正、小嶋哲人
    • Organizer
      第37回日本血栓止血学会学術集会
    • Place of Presentation
      甲府
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] A congenital dysprothrombinemia with both decreased prothrombin activity and antithrombin resistance2015

    • Author(s)
      高田麻央、森下英里子、谷口文苗、關口暁子、小林英里奈、朝倉英策、高木明、小嶋哲人、大竹茂樹
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] プロトロンビン Arg596 における一塩基置換ミスセンス変異体のトロンボモジュリン 抵抗性評価2015

    • Author(s)
      高木夕希、村田 萌、中村友紀、小塚敏弘、中田悠紀子、長谷部瞭、橋本恵梨華、高木 明、小嶋哲人
    • Organizer
      第37回日本血栓止血学会学術集会
    • Place of Presentation
      甲府
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] プロトロンビンArg596 における一塩基置換ミスセンス変異体のトロンボモジュリン抵抗性評価2015

    • Author(s)
      高木夕希、村田萌、中村友紀、小塚敏弘、中田悠紀子、長谷部瞭、橋本恵梨華、高木明、小嶋哲人
    • Organizer
      第37回日本血栓止血学会学術集会
    • Place of Presentation
      甲府
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] Analysis of prothrombin missense mutants at 596ARG by single nucleotide substitution for anticoagulant system2015

    • Author(s)
      Yuki Takagi, Moe Murata, Yuki Nakamura, Toshihiro Kozuka, Yukiko Nakata, Ryo Hasebe, Akira Takagi, Tetsuhito Kojima
    • Organizer
      XXV Congress of International Society on Thrombosis and Haemostasis
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2015-06-20
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] 深部静脈血栓症で発症しアンチトロンビン抵抗性を示した本邦初 Prothrombin Belgrade 変異の一家系2015

    • Author(s)
      岸本磨由子、鈴木伸明、村田萌、小川実加、兼松毅、高木明、小嶋哲人、松下正
    • Organizer
      第37回日本血栓止血学会学術集会
    • Place of Presentation
      甲府
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] 先天性アンチトロンビン欠乏症8症例SERPINC1遺伝子解析2015

    • Author(s)
      中田悠紀子、小塚敏弘、長谷部瞭、高木夕希、村田 萌、上牧 務、松尾真稔、高木 明、松下 正、小嶋哲人
    • Organizer
      第16回日本検査血液検査血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-07-11
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] 新たな血栓性素因:アンチトロンビン・レジスタンス2015

    • Author(s)
      小嶋哲人
    • Organizer
      第25回日本産婦人科新生児血液学会
    • Place of Presentation
      東京
    • Year and Date
      2015-06-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] 血小板無力症に同定された GPIIb 遺伝子のミスセンス変異とスプライス変異の複合ヘテロ変異解析2015

    • Author(s)
      橋本恵梨華、村田萌、槇山愛弓、河村奈美、小塚敏弘、中田悠紀子、長谷部瞭、高木夕希、水谷直貴、高木明、國島 伸治、松下正、小嶋哲人
    • Organizer
      第37回日本血栓止血学会学術集会
    • Place of Presentation
      甲府
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] Practical laboratory assay to detect abnormal prothrombin conveying thrombomodulin resistance.2015

    • Author(s)
      高木夕希、水谷直貴、村田萌、小塚敏弘、中田悠紀子、長谷部瞭、河村奈美、槇山愛弓、橋本恵梨華、高木明、小嶋哲人
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] アンチトロンビン抵抗性検出検査法の自動凝固検査機器への最適化 Part 22015

    • Author(s)
      村田萌、水谷直貴、高木夕希、長谷部瞭、小塚敏弘、中田悠紀子、高木明、松下正、小嶋哲人
    • Organizer
      第16回日本検査血液検査血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-07-11
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] 深部静脈血栓症で発症したアンチトロンビンレジスタンス症例の抗凝固療法2015

    • Author(s)
      岸本磨由子、鈴木伸明、村田 萌、小川実加、兼松 毅、高木 明、小嶋哲人、松下 正
    • Organizer
      第16回日本検査血液検査血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-07-11
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] 原因不明であった静脈血栓塞栓症にみられたアンチトロンビン抵抗性を示す本邦2家系目のプロトロンビン異常症2014

    • Author(s)
      村田 萌、高木夕希、中村友紀、長谷部 瞭、小塚敏弘、中田 悠紀子、高木 明、村手 隆、松下 正、小嶋哲人
    • Organizer
      第33回日本臨床検査医学会東海・北陸支部例会
    • Place of Presentation
      名古屋大学鶴舞キャンパス
    • Year and Date
      2014-08-02
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] アンチトロンビン抵抗性の関与が疑われた家族性再発性肺血栓塞栓症の1例2014

    • Author(s)
      吉田 律、角田 聖子、長谷川 潤、大木 理次、武本 知之、小山 達也、山崎 弘二、関 晋吾、吉村 道博、高木 明、小嶋 哲人
    • Organizer
      第233回日本循環器学会 関東・甲信越地方会
    • Place of Presentation
      東京
    • Year and Date
      2014-09-06
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] 原因不明であった静脈血栓塞栓症にみられたアンチトロンビン抵抗性を示す本邦2家系目のプロトロンビン異常症2014

    • Author(s)
      村田 萌、高木 明、岸本磨由子、清井 仁、松下 正、小嶋哲人
    • Organizer
      第33回日本臨床検査医学会東海・北陸支部例会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-08-02
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] Regulatory mechanism of SPHK2 expresssion in colon cancer cell lines2013

    • Author(s)
      Mizutani N, Inoue M, Nishida Y, Omori Y, Suzuki M, Koizumi K, Takagi A, Kojima T, Iwaki S, Fujii S, Nakamura M, Banno Y, Nozawa Y, Murate T
    • Organizer
      7^<th> International Conference of Ceramide
    • Place of Presentation
      Montauk, NY. USA
    • Year and Date
      2013-10-21
    • Data Source
      KAKENHI-PROJECT-23590667
  • [Presentation] A clinical laboratory test detecting antithrombin resistance of the new thrombophilia2013

    • Author(s)
      MURATA Moea, TAKAGI Akira, SUZUKI Atsuo,TAKAGI Yuki, KATO Io, ANDO Yumi, MURATE Takashi, MATSUSHITA Tadashi, SAITO Hidehiko, KOJIMA Tetsuhito
    • Organizer
      XXIV Congress of International Society on Thrombosis and Haemostasis,
    • Place of Presentation
      Amsterdam, The Neterlands
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] A novel mechanism of hereditary thrombosis by antithrombin resistance.2013

    • Author(s)
      Tetsuhito Kojima
    • Organizer
      XXIV Congress of nternational Society on Thrombosis and Haemostasis
    • Place of Presentation
      Amsterdam, The Neterlands
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] アンチトロンビン抵抗性解析法の改良と評価2013

    • Author(s)
      村田 萌、高木 明、中村友紀、加藤衣央、安藤裕実、高木夕希、村手 隆、松下 正、小嶋哲人
    • Organizer
      第14回日本検査血液検査血液学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] The mechanism of cytotoxicity by resveratrol against human leukemia cell lines2013

    • Author(s)
      Omori Y, Mizutani N, Inoue M, Nishida Y, Suzuki M, Koizumi K, Takagi A, Kojima T, Iwaki S, Fujii S, Nakamura M, Nozawa Y, Murate T
    • Organizer
      7^<th> International Conference of Ceramide
    • Place of Presentation
      Montauk, NY. USA
    • Year and Date
      2013-10-22
    • Data Source
      KAKENHI-PROJECT-23590667
  • [Presentation] Genetic risk factors for thrombophilia in Japanese2013

    • Author(s)
      Tetsuhito Kojima
    • Organizer
      Annual Meeting of Korean Society on Thrombosis and Haemostasis
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] プロトロンビンYukuhashi由来変異型トロンビンのトロンボモジュリン・プロテインC系に及ぼす影響2013

    • Author(s)
      高木夕希、高木 明、鈴木敦夫、奥山恵理子、村田 萌、加藤衣央、安藤裕実、中村友紀、松下 正、齋藤英彦、小嶋哲人
    • Organizer
      第14回日本検査血液検査血液学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] Effects of prothrombin Yukuhashi mutation on thrombomodulin-protein C system2013

    • Author(s)
      TAKAGI Yuki, KAT O Io, ANDO Yumi, MURATA Moea, SUZUKI Atsuo, TAKAGI Akira, MATSUSHITA Tadashi, SAITO Hidehiko, KOJIMA Tetsuhito
    • Organizer
      XXIV Congress of International Society on Thrombosis and Haemostasis,
    • Place of Presentation
      Amsterdam, The Neterlands
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] 静脈血栓塞栓症リスク・アンチトロンビン抵抗性とそのスクリーニング検査2012

    • Author(s)
      高木 明、 宮脇由理、 鈴木敦夫、藤田絢子、牧明日加、奥山恵理子、村田 萌、村手 隆、松下 正、 小嶋哲人
    • Organizer
      第34回日本血栓止血学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22659114
  • [Presentation] Up-regulation mechanisms of syndecan-4, a heparan sulfate proteoglycan, expression by TNF-a in human endothelial like EAhy926 cells2012

    • Author(s)
      Okuyama E, Murata M, Suzuki A, Ando Y, Kato I, Takagi Y, Takagi A, Murate T, Saito T, Kojima T
    • Organizer
      第35回日本分子生物学会年
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] Molecular mechanisms of syndecan-4 upregulation by TNF-. in the endothelial-like EAhy926 cells2012

    • Author(s)
      Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Miyawaki Y, Suzuki A, Takagi A, Murate T, Saito T, Kojima T
    • Organizer
      第74回日本血液学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] A Possible Mechanism for Inv22-related F8 Large Deletions in Severe Hemophilia A Patients with High Responding Factor VIII Inhibitors.2012

    • Author(s)
      Fujita J, Miyawaki Y, Suzuki A, Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Hosaka M, Takagi A, Murate T, Kajiura Y, Suzuki N, Matsushita T, Saito H, Kojima T
    • Organizer
      VIIth Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
    • Place of Presentation
      Meibourun, Australia
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] A Possible Mechanism for Inv22-related F8 Large Deletions in Severe Hemophilia A Patients with High Responding Factor VIII Inhibitors2012

    • Author(s)
      Fujita J, Miyawaki Y, Suzuki A, Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Hosaka M, Takagi A, Murate T, Kajiura Y, Suzuki N, Matsushita T, Saito T, Kojima T
    • Organizer
      VIIth Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] NF-kappaB is essential for Syndecan-4 up-regulation by TNF-alpha in Vascular Endothelial-like EAhy926 Cells2012

    • Author(s)
      Okuyama E, Murata M, Suzuki A, Miyawaki Y, Ando Y, Kato I, Takagi Y, Takagi A, Murate T, Saito T, Kojima T
    • Organizer
      VIIth Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] Immunosuppressant IMP dehydrogenase inhibitors up-regulated coagulation factor VII mRNA2012

    • Author(s)
      Suzuki A, Miyawaki Y, Okuyama E, Murata M, Ando Y, Kato I, Takagi Y, Takagi A, Murate T, Saito T, Kojima T
    • Organizer
      第74回日本血液学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] Molecular Basis of Coagulation Factor IX Gene Abnormalities in 16 Japanese Hemophilia B Patients2012

    • Author(s)
      Murata M, Okuyama E, Suzuki A, Miyawaki Y, Ando Y, Kato I, Takagi Y, Hosaka M, Takagi A, Murate T, Kishimoto, M, Suzuki N, Matsushita T, Saito T, Kojima T
    • Organizer
      VIIth Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] Historical perspective and future direction of coagulation research2011

    • Author(s)
      H Saito, T Matsushita, T Kojima
    • Organizer
      XXIIIrd Congress of ISTH
    • Place of Presentation
      京都国際会議場(招待講演)
    • Year and Date
      2011-07-27
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] アンチトロンビン抵抗性解析法とその評価2011

    • Author(s)
      高木明、 宮脇由理、 鈴木敦夫、藤田絢子、牧明日加、奥山恵理子、村田萌、村手隆、松下正、小嶋哲人
    • Organizer
      第58回日本臨床検査医学会学術集
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-22659114
  • [Presentation] PS-1-72: Unusual X-chromosomal rearrangements with F8-int22 inversion in three severe hemophilia A patients2011

    • Author(s)
      Fujita J, Miyawaki Y, Suzuki A, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Matsushita T, Suzuki N, Saito H, Kojima T
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] 血栓性素因の病因と病態2011

    • Author(s)
      小嶋哲人
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋国際会議場(招待講演)
    • Year and Date
      2011-10-16
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] A NOVEL PROTHROMBIN GENE MUTATION LEADS TO AN AT-RESISTANT THROMBIN IN A FAMILY WITH INHERITED THROMBOPHILIA2011

    • Author(s)
      Miyawaki Y, Suzuki A, Fujimori Y, Fujita J, Maki A, Takagi A, Murate T, Sakai M, Okamoto K, Matsushita T, Kojima T
    • Organizer
      XXIIIrd Congress of International Society on Thrombosis and Haemostasis
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] A novel prothrombin gene mutation leads to an at-resistant thrombin in afamily with inherited thrombophilia2011

    • Author(s)
      Miyawaki Y, Suzuki A, Fujimori Y, Fujita J, Maki A, Takagi A, Murate T, Sakata M, Okamoto K, Matsushita T, Kojima T
    • Organizer
      XXIIIth CONGRESS OF THE INTERNATIONAL SOCIETY ON THROMBOSIS AND HAEMOSTASIS
    • Place of Presentation
      KYOTO
    • Data Source
      KAKENHI-PROJECT-22659114
  • [Presentation] PS-1-63: Thrombophilia and JAK2 V617F mutations in Japanese patients with Budd-Chiari syndrome2011

    • Author(s)
      Maki A, Fujita J, Okuyama E, Murata M, Miyawaki Y, Suzuki A, Takagi A, Murate T, Kojima T
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] 教育講演:基本シリーズ:血栓・止血 血栓性素因の病因と病態2011

    • Author(s)
      小嶋哲人
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] OS-3-120: Molecular basis of an AT-resistant variant thrombin found in a Japanese family with thrombophilia2011

    • Author(s)
      Miyawaki Y, Suzuki A, Fujita J, Maki A, Okuyama E, Murata M, Takagi A, Murate T, Kunishima S, Sakai M, Okamoto K, Matsushita T, Kojima T
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] アンチトロンビン抵抗性を検出するトロンビン不活化動態解析法の開発2011

    • Author(s)
      高木 明、 宮脇由理、 鈴木敦夫、藤田絢子、牧明日加、奥山恵理子、村田 萌、村手 隆、松下 正、小嶋哲人
    • Organizer
      12回日本検査血液学会学術集会
    • Place of Presentation
      倉敷
    • Data Source
      KAKENHI-PROJECT-22659114
  • [Presentation] DISTINCT X-CHROMOSOMAL REARRANGEMENTS WITH F8-INTRON22 INVERSION IN THREE UNRELATED JAPANESE SEVERE HEMOPHILIA A PATIENTS WITH HIGH TITER INHIBITOR2011

    • Author(s)
      Fujita J, Suzuki A, Miyawaki Y, Maki A, Fujimori Y, Takagi A, Murate T, Matsushita T, Suzuki N, Saito H, Kojima T
    • Organizer
      XXIIIrd Congress of International Society on Thrombosis and Haemostasis
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] Historical perspective and future direction of coagulation research2011

    • Author(s)
      Saito H, Matsushita T, Kojima T
    • Organizer
      XXIIIrd Congress of International Society on Thrombosis and Haemostasis
    • Place of Presentation
      XXIIIrd Congress of International Society on Thrombosis and Haemostasis
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] Receptor interacting protein 140 (RIP140) mediated ERα-Sp1 and corepressor-HDAC3 complex association in 17β-estradiol dependent down-regulation of protein S2010

    • Author(s)
      A Suzuki, Y Miyawaki, J Fujita, A Maki, Y Fujimori, A Takagi, T Murate, H Saito, T Kojima
    • Organizer
      第33回日本分子生物学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] A novel endoglin gene mutation associated with hereditary hemorrhagic telangiectasia in a Japanese2010

    • Author(s)
      A Suzuki, Y Miyawaki, J Fujita, A Maki, Y Fujimori, A Takagi, T Murate, M Teranishi, H Saito, T Kojima
    • Organizer
      第72回日本血液学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] Genetic Disorders Related to Coagulopathy Prevalent in the Far East2010

    • Author(s)
      T Kojima
    • Organizer
      6th Congress of the Asia Pacific Society on Thrombosis and Haemostasis (APSTH Bali 2010)
    • Place of Presentation
      Bali
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] A survey of venous thromboembolism in Japanese patients with inherited anticoagulant deficiency2010

    • Author(s)
      K Yokoyama, T Kojima, Y Sakata, T Kawasaki, H Tsuji, T Miyata, S Okamoto, M Murata
    • Organizer
      第72回日本血液学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22590524
  • [Presentation] シンポジウム2「血栓性素因の病態と診断の進歩」 : 血栓性素因のとしてのATとPC異常2008

    • Author(s)
      小嶋哲人
    • Organizer
      第9回日本検査血液学会学術集会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2008-07-26
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] 新規Gr cm pI 変異L1503R のv cm Wi11ebrand病type2A発症における役割2008

    • Author(s)
      平島寛司、柏木隆宏、松下正、伊藤康友、高木明、村手隆、勝見章、直江知樹、小嶋哲人
    • Organizer
      第31回日本血栓止血学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2008-11-21
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] 新規Group I 変異L1503R のvonWillebrand 病type 2A発症における役割2008

    • Author(s)
      柏木隆宏、松下正、伊藤康友、高木明、村手隆、勝見章、平島寛司、直江知樹、小嶋哲人
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Year and Date
      2008-11-12
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] 「抗血栓薬の最近の進歩」関連学会ジョイントシンポジウム2008

    • Author(s)
      小嶋哲人
    • Organizer
      日本循環器学会 第31回日本血栓止血学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2008-11-21
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] 第VIII因子遺伝子のイントロン22逆位解析法-DNAポリメラーゼの比較-2008

    • Author(s)
      藤森祐多、山田貴之、奥村 薫、田中亮子、中島大輔、鈴木敦夫、宮脇由理、高木明、村手 隆、小嶋哲人
    • Organizer
      第9回日本検査血液学会学術集会
    • Place of Presentation
      津
    • Year and Date
      2008-07-26
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] Regulatory mechanism of neutral sphingomyelinase 2 gene expression by daJnorubicin in MCF-7 cells2008

    • Author(s)
      H Ito, M Murakami, S Gao, A Furuhata, K Yoshida, Y Tagawa, S Sobue, A Takagi, T Kojima, M Suzuki, Y Banno, Y Nozawa, K Koizumi, T Murate
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] GATA-1, GATA-2 によるWT1発現調節の解析2008

    • Author(s)
      古畑彩子、村上真史、高 四強、木村有美、伊藤裕美、高木 明、小嶋哲人、安部明弘、直江知樹、村手 隆
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Year and Date
      2008-10-12
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] 日本人における血栓性素因遺伝子変異データベースの作成2008

    • Author(s)
      藤森祐多, 小嶋哲人, ほか
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2008-10-12
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] ATRA inhibits ceramide kinase transcription through an ATRA-related transcription factor, COU~-TF1, in a human neuroblastoma cell line, SH-SY5Y cells2008

    • Author(s)
      M Murakami, H Ito, S Gao, A Furuhata, K Yoshida, Y Tagawa, S Sobue, A Takagi, T Kojima, M Suzuki, Y Banno, Y Nozawa, T Murate
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] v-SrcによるSPHKl mRNA安定化と発現増強2008

    • Author(s)
      祖父江沙矢加、村上真史、坂野喜子、伊藤裕美、高四強、古畑彩子、高木明、小嶋哲人、野澤義則、村手隆、市原正智
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] シンポジウム2「血栓性素因の病態と診断の進歩」 : 血栓性素因のとしてのAT とPC異常2008

    • Author(s)
      小嶋哲人
    • Organizer
      第9回日本検査血液学会学術集会
    • Place of Presentation
      津
    • Year and Date
      2008-07-26
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] 日本人の血栓症の遺伝的背景に関する調査研究2008

    • Author(s)
      宮田敏行、川崎富夫、辻肇、窓岩清治、坂田洋一、小嶋哲人、村田満、阪田敏幸、竹下聡、小久保喜弘、小亀浩一、岡田裕美、池田康夫
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Year and Date
      2008-10-12
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] 日本人の血栓症の遺伝的著景に関する調査研究2008

    • Author(s)
      宮田敏行, 小嶋哲人, ほか
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2008-10-12
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] 先天性凝固第VII 因子欠損症の分子病態解析2008

    • Author(s)
      田中亮子、中島大輔、鈴木敦夫、宮脇由理、藤森祐多、山田貴之、奥村薫、勝見章、山本晃士、松下正、高松純樹、高木明、村手隆、小嶋哲人
    • Organizer
      第31回日本血栓止血学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2008-11-22
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] 日本人における血栓性素因遺伝子変異データベースの作成2008

    • Author(s)
      藤森祐多、奥村薫、山田貴之、田中亮子、中島大輔、鈴木敦夫、宮脇由理、村手隆、高木明、小嶋哲人
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Year and Date
      2008-10-12
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] Mutated Ras-induced. Phospholipase D1 transcripton in a human colon adenocarcinoma celt line, DLD-12008

    • Author(s)
      S Gao, M Murakami, H Ito, A Furuhata, K Yoshida, Y Tagawa, S Sobue, A Takagi, T Kojima, Y Banno, M Suzuki, Y Nozawa, T Murate
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] 女性血友病Aの分子病態解析2008

    • Author(s)
      宮脇由理、鈴木敦夫、田中亮子、中島大輔、藤森祐多、山田貴之、奥村 薫、高木明、村手 隆、松下正、高松純樹、小嶋哲人
    • Organizer
      第31回日本血栓止血学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2008-11-21
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] 女性血友病Aの1例2008

    • Author(s)
      宮脇由理、鈴木敦夫、田中亮子、中島大輔、藤森祐多、山田貴之、奥村薫、高木明、村手 隆、松下正、高松純樹、小嶋哲人
    • Organizer
      第9回愛知県医学検査学会
    • Place of Presentation
      豊橋
    • Year and Date
      2008-05-25
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] 先天性プロテインC欠損症7家系における遺伝子解析2007

    • Author(s)
      田中亮子、中島大輔、柏木隆宏、三田直美、藤森祐多、山田貴之、奥村薫、勝見章、松下正、山本晃士、高松純樹、高木明、村手隆、小嶋哲人
    • Organizer
      第30回日本血栓止血学会学術集会
    • Place of Presentation
      志摩
    • Year and Date
      2007-11-16
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] 60歳時からの鼻出血で発症した遺伝性出血性末梢血管拡張症の遺伝子解析2007

    • Author(s)
      中島大輔、田中亮子、柏木隆宏、三田直美、藤森祐多、山田貴之、奥村薫、寺西正明、高木明、村手隆、小嶋哲人
    • Organizer
      第30回日本血栓止血学会学術集会
    • Place of Presentation
      志摩
    • Year and Date
      2007-11-16
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] X染色体の不活性化を伴う女児血友病Bの分子病態解析2007

    • Author(s)
      奥村薫、山田貴之、柏木隆宏、三田直美、藤森祐多、田中亮子、中島大輔、松下正、小関道夫、高木明、村手隆、小嶋哲人
    • Organizer
      第30回日本血栓止血学会学術集会
    • Place of Presentation
      志摩
    • Year and Date
      2007-11-16
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] Molecular basis of antithrombin deficiency in four Japanese patients with pregnancy-associated thrombosis : antithrombin gene abnormalities including two novel mutations2007

    • Author(s)
      K. Okumura, Y. Fujimori, T. Kashiwagi, N. Sanda, T. Yamada, A. Takagi, T. Murate, T. Iwasaki, A. Katsumi, K. Yamamoto, T. Matsushita, T. Naoe, H. Saito, T. Kojima
    • Organizer
      XXIInd Congress of ISTH, Geneva
    • Place of Presentation
      Switzerland
    • Year and Date
      2007-07-11
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] Molecular basis of antithrombin deficiency in four Japanese patients with Pregnancy-associated thrombosis: antithrombin gene abnormalities inc1uding two novel mutations.2007

    • Author(s)
      K. Okumura, T. Kojima, et. al.
    • Organizer
      XXIInd Congress of ISTH
    • Place of Presentation
      Geneva, Switzerlamd
    • Year and Date
      2007-07-09
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] JAK2V617F変異がもたらすBcl-XL発現増加とその転写調節機序の解明2007

    • Author(s)
      木村有美、伊藤裕美、祖父江沙矢加、村上真史、根本聡、高四強、古畑彩子、高木明、小嶋哲人、幣光太郎、村手隆
    • Organizer
      第69回日本血液学会・第49回日本臨床血液学会 合同総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-13
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] The protein S thrombin sensitive region contributes regulation of warfarin treated des-γ-carboxylated protein S secretion: a study of a novel splice site mutation of protein S gene and its molecular consequences2007

    • Author(s)
      H. Okada, S. Kunishima, M. Hamaguchi, A. Takagi, K. Yamamoto, J. Takamatsu, T. Matsushita, H. Saito, T. Kojima, T. Yamazak
    • Organizer
      XXIInd Congress of ISTH
    • Place of Presentation
      Geneva, Switzerland
    • Year and Date
      2007-07-19
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] One-Third of Japanese patients with deep vein thrombosis carried the genetic mutations in proteins S, C and antithrombin genes: the sub-group study of blood coagulation abnormality the study group of research on measures for intractable diseases in Japan2007

    • Author(s)
      J. Ishikawa, Y. Sato, S. Takeshita, K. Kokame, R. Kimura, S. Honda, T. Kawasaki, E. Suehisa, H. Tsuji, S. Madoiwa, Y. Sakata, T. Kojima, M. Murata, Y. Ikeda, T. Miyata
    • Organizer
      XXIInd Congress of ISTH
    • Place of Presentation
      Geneva, Switzerland
    • Year and Date
      2007-07-10
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] PROS1遺伝子プロモーテー領域内の一塩基置換による先天性プロテインS欠損症2007

    • Author(s)
      三田直美、柏木隆宏、藤森祐多、田中亮子、中島大輔、山田貴之、奥村薫、高木明、村手隆、小嶋哲人
    • Organizer
      第8回日本検査血液学会学術集会
    • Place of Presentation
      福井
    • Year and Date
      2007-07-22
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] アンチトロンビン欠損症と拡張型心筋症の合併家系における分子病態解析2007

    • Author(s)
      藤森祐多、沖松秀美、柏木隆宏、三田直美、田中亮子、中島大輔、山田貴之、奥村薫、高木明、村手隆、内田文、野出孝一、小嶋哲人
    • Organizer
      第69回日本血液学会・第49回日本臨床血液学会 合同総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-13
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] The protein S thrombin sensitive region contributes regulation of warfarin treated des-γ-carboxylated protein S secretion: a study of a novel splice site mutation of protein S gene and its molecular Consequences.2007

    • Author(s)
      N. Okada, T. Kojima, et. al.
    • Organizer
      XXIInd Congress of IFTH
    • Place of Presentation
      Geneva, Seitzerlamd
    • Year and Date
      2007-07-09
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] Four novel causative mutations identified in the PROS1 gene of Japanese deep vein thrombosis patients with protein S deficiency2007

    • Author(s)
      N. Sanda, Y. Fujimori, T. Kashiwagi, T. Yamada, K. Okumura, A. Takagi, T. Murate, T. Iwasaki, A. Katsumi, K. Yamamoto, T. Matsushita, T. Naoe, H. Saito, T. Kojima
    • Organizer
      XXIInd Congress of ISTH
    • Place of Presentation
      Geneva, Switzerland
    • Year and Date
      2007-07-10
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] A large deletion of the PROS1 gene in a deep vein thrombosis patient with protein S deficiency2007

    • Author(s)
      T. Yin, S. Takeshita, Y. Sato, T. Sakata, Y. Shin, S. Honda, T. Kawasaki, H. Tsuji, S. T. Kojima, Madoiwa, Y. Sakata, M. Murata, Y. Ikeda, T. Miyata
    • Organizer
      XXIInd Congress of ISTH
    • Place of Presentation
      Geneva, Switzerland
    • Year and Date
      2007-07-10
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] 白血病細胞株におけるSPHK1発現と抗癌剤Daunorubicin体制との関連2007

    • Author(s)
      祖父江沙矢加、村上真史、根本聡、伊藤裕美、木村有美、高四強、古畑彩子、高木明、小嶋哲人、村手隆
    • Organizer
      第69回日本血液学会・第49回日本臨床血液学会 合同総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-11
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] Four nove1 causative mutations identified in the PROS1 gene of Japanes o deeP vein thrombosis patients with protein S deficiency.2007

    • Author(s)
      N. Sanda, T. Kojima, et. al.
    • Organizer
      XXIInd Congress of ISTH
    • Place of Presentation
      Geneva, Switzerlamb
    • Year and Date
      2007-07-10
    • Data Source
      KAKENHI-PROJECT-19590553
  • [Presentation] Precise genetic abnormalities in four hemophilia B patients with large deletions of X-chromosome including entire F8

    • Author(s)
      Yuki Nakamura, Moe Murata, Yuki Takagi, Toshihiro Kozuka, Yukiko Nakata, Ryo Hasebe, Akira Takagi, Tadashi Matsushita, Tetsuhito Kojima
    • Organizer
      The 8th Congress of Asia Pacific Society of Thrombosis and Hemostasis
    • Place of Presentation
      Hanoi
    • Year and Date
      2014-10-09 – 2014-10-11
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] Antithrombin resistance: a new mechanism of inherited thrombophilia

    • Author(s)
      小嶋哲人
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-10-31 – 2014-11-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] Optimization of the antithrombin resistance assay for the automated analyzer

    • Author(s)
      Moe Murata, Yuki Takagi, Yuki Nakamura, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Tetsuhito Kojima
    • Organizer
      The 8th Congress of Asia Pacific Society of Thrombosis and Hemostasis
    • Place of Presentation
      Hanoi
    • Year and Date
      2014-10-09 – 2014-10-11
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] アンチトロンビン抵抗性検出検査法の自動凝固検査機器への最適化

    • Author(s)
      村田 萌、高木夕希、中村友紀、長谷部 瞭、小塚敏弘、中田 悠紀子、高木 明、村手 隆、松下 正、小嶋哲人
    • Organizer
      第15回日本検査血液検査血液学会学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2014-07-20 – 2014-07-21
    • Data Source
      KAKENHI-PROJECT-25460683
  • [Presentation] Optimization of the antithrombin resistance assay for the automated analyzer

    • Author(s)
      Moe Murata, Yuki Takagi, Yuki Nakamura, Ryo Hasebe, Toshihiro Kozuka, Yukiko Nakata, Akira Takagi, Tetsuhito Kojima
    • Organizer
      The 8th Congress of Asia Pacific Society of Thrombosis and Hemostasis (APSTH)
    • Place of Presentation
      Hanoi, Vietnam
    • Year and Date
      2014-10-09 – 2014-10-11
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] Precise genetic abnormalities in four hemophilia B patients with large deletions of X-chromosome including entire F9

    • Author(s)
      Yuki Nakamura, Moe Murata, Yuki Takagi, Toshihiro Kozuka, Yukiko Nakata, Ryo Hasebe, Akira Takagi, Tadashi Matsushita, Tetsuhito Kojima
    • Organizer
      The 8th Congress of Asia Pacific Society of Thrombosis and Hemostasis (APSTH)
    • Place of Presentation
      Hanoi, Vietnam
    • Year and Date
      2014-10-09 – 2014-10-11
    • Data Source
      KAKENHI-PROJECT-25293129
  • [Presentation] アンチトロンビン抵抗性検出検査法の自動凝固検査機器への最適化

    • Author(s)
      村田 萌、高木夕希、中村友紀、長谷部 瞭、小塚敏弘、中田 悠紀子、高木 明、村手 隆、松下 正、小嶋哲人
    • Organizer
      第15回日本検査血液検査血液学会学術集会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2014-07-20 – 2014-07-21
    • Data Source
      KAKENHI-PROJECT-25293129
  • 1.  TAKAGI Akira (30135371)
    # of Collaborated Projects: 15 results
    # of Collaborated Products: 163 results
  • 2.  YAKMAMOTO Koji (90362251)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 21 results
  • 3.  MATSUSHITA Tadashi (30314008)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 79 results
  • 4.  MURATE Takashi (30239537)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 9 results
  • 5.  SAITO Hidehiko (20153819)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 6.  SUZUKI Motoshi (80236017)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 9 results
  • 7.  BANNO Yoshiko (50116852)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 8.  TUZUKI Shinobu
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  TOWATARI Masayuki
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  NOZAWA Yoshinori (10021362)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  TAKAMATSU Junnki (80221365)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  KADOMATSU Kenji (80204519)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  TANIMOTO Mitsune (10240805)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  ABE Akihiro
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  KOIZUMI Keiko (00118027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  HAMAGUCHI Motohiro (30393177)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  YAMAZAKI Tomio (00282202)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  KUNISHIMA Shinji (60373495)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 19.  TSUDA Hiroko (30180003)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  NAKAZONO Eri (10343732)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  NOGUCHI Kenta (90757494)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  MORISHITA Eriko (50251921)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  KATO Kiyoko (10253527)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  HAYASHI Tatsuya (00242959)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  OZAKI Yukio (30134539)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  MIYATA Toshiyuki (90183970)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  Tamura Shogo (60722626)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 31 results
  • 28.  濱崎 直孝 (00091265)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  隈 博幸 (40435136)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  佐々木 知幸 (40739124)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  TSUDA Tomohide
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  松岡 明
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  安部 明宏
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  Oh Doyeun
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  Lee Lai Heng
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  Bereczky Zsuzsanna
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  Dusse Luci
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  Carvalho Maria
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  KATSUMI Akira
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 40.  ITO Hiromi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  IWAKI Soichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 42.  SUZUKI Yuko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  URANO Tetsumei
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  IWAKI Takayuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  TANINO Mishie
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  ENDO Yuichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 47.  SUZUKI Toshiyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 48.  TSUCHIYA Kohsuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  SHI Lei
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 50.  早川 文彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 51.  鈴木 伸明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 6 results
  • 52.  清井 仁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 53.  中村 光浩
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 54.  加藤 省一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 55.  岡本 好司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 56.  藤井 聡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 57.  本橋 ほづみ
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 58.  菊地 利明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 59.  石上 雅敏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 60.  石川 哲也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 61.  本多 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 62.  野沢 義則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 63.  谷野 功典
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 64.  村田 萌
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 65.  丸山 彰一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 66.  伊川 正人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 67.  齋藤 都暁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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