NOBUHIKO Emi 恵美宣彦

… Alternative Names

EMI Nobuhiko 恵美宣彦

Less

Researcher Number	30185144
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2020: 藤田医科大学, 医学部, 教授 2013 – 2017: 藤田保健衛生大学, 医学部, 教授 2015: 藤田保健衛生大学, 血液内科, 教授 2005 – 2006: 藤田保健衛生大学, 医学部, 助教授 2004: 名古屋大学, 医学研究科, 助教授 … More 2003 – 2004: 名古屋大学, 大学院・医学系研究科, 助教授 2002: Nagoya University Hospital, Assistant Professor, 医学部附属病院, 講師 2001 – 2002: 名古屋大学, 医学部・附属病院, 講師 1997 – 2000: 名古屋大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Hematology Except Principal Investigator Hematology / Hematology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor diagnostics / Biomedical engineering/Biological material science / General surgery
Keywords	Principal Investigator PDGFR / Leukemia / CEV / SYK / CEV14 / 白血病 / Tyrosine kinase / PI3K / STAT5 / TEL / チロシンキナーゼ / Chromosome / 染色体 … More Except Principal Investigator … More 癌 / PSAP / JAK3 / JAK2 / 白血病 / eNOS / SYK / CEV / SEREX / GVL / Leukemia / ワクチン / RNA-seq / G-CSF / 染色体転座 / オーロラBキナーゼ / アンチセンスオリゴヌクレオチド / アンチセンスヌクレオチド / Pre-mRNAスプライシング / mRNAスプライシング / RNPS1 / オーロラB / ゲノム / 遺伝子 / 複雑核型 / 融合遺伝子 / 造血器腫瘍 / EMID1 / ARID1B / MAML3 / TCF4 / RUNX1 / translocation / fusion gene / プロテオーム / p53 / 品質管理機構 / mRNA / 遺伝子発現 / RBM4a / RNPS / EJC / eIF4A3 / TSG101 / スプライシング完了機構 / mRNA品質管理機構 / スプライシング / 遺伝子発現調節 / surrogate marker / target therapy / cell signaling / leukemia / チロシンキナーゼ / 発現クローニング法 / FLT3 / キナーゼ阻害剤 / 変異 / ヌクレオフォスミン / 造血器腫瘍 / サロゲートマーカー / 標的治療 / シグナル伝達 / nano-medicine / drug delivery system / liposome / lipoplex / nano-bio / gene delivery / non-viral vector / gene therapy / ベクタ / ドラッグデリバリーシステム / ナノ医薬 / 遺伝子導入 / リポプレックス / ドラッグデリバリーシステ / ナノ医療 / ナノバイオ / リポソーム / ベクター / 遺伝子治療 / prevention of intimal hyperplasia / statin / perlipheral vascular disease / pregenitor cells / intimal hyperplasia / プラバスタチン / 頸動脈自家静脈バイパス / 内膜肥圧抑制 / 内膜肥厚抑制 / スタチン / 末梢動脈疾患 / 骨髄前駆細胞 / グラフト内膜肥厚 / DNA Vaccine / Gene Gun / Vaccine / SFV / DC / デンドリマー / マンノース / チロシンリン酸化 / PDGFR / DNAワクチン / 遺伝子銃 / Immunogene / Idiotype Vaccine / 薬剤の安全性 / マテリアル / NAGL-1 / CTL / idiotype / Idiotype / B細胞性腫瘍 / 遺伝子ワクチン / Idiutype / HOXA9 / NUP98 / ケモカイン / 細胞遊走 / SDF1 / サイトカイン / ETV6-LPXN / CXCL12 / LPXN / ETV6 Less

The development of therapeutic antisense oligonucleotide targeted to aurora kinase B as an anti-cancer drug
- Principal Investigator
  
  FUKUMURA KAZUHIRO
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Fujita Health University
Exploring the implications of cancer-specific mRNA re-splicing events in the robustness and catastrophe of gene expression system
- Principal Investigator
  
  Mayeda Akila
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Fujita Health University
Identification and functional analysis of gene aberrations in hematological malignancy with complex chromosomal abnormality using RNA-seq analysis
- Principal Investigator
  
  ABE AKIHIRO
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Fujita Health University
Analyses of cytokine responsive signaling of LPXN and enhanced responses caused by ETV6-LPXN
- Principal Investigator
  
  ABE Akihiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Fujita Health University
Preparation of efficient gene vectors with multi functions
- Principal Investigator
  
  KONO Kenji
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Osaka Prefecture University
Analysis of aberrant signal tansduction in hematological malignancy and development of treatment methods.
- Principal Investigator
  
  NAOE Tomoki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Relationshio pregenitor cells derived from bone marrow and graft intimal hyperplasia
- Principal Investigator
  
  KOBAYASHI Masayoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Nagoya University
Analysis of tyrosine kinase chimeric genePrincipal Investigator
- Principal Investigator
  
  EMI Nobuhiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Novel immunotherapy for Hematological Malignancy
- Principal Investigator
  
  SAITO Hidehiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Analysis of CEV14-PDGFR chimeric genePrincipal Investigator
- Principal Investigator
  
  EMI Nobuhiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Development of Immunogene Therapy for B-cell malignancy
- Principal Investigator
  
  SAITO Hidehiko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  NAGOYA UNIVERSITY

All 2020 2019 2018 2017 2016 2015 2014 2006 2005 Other

All Journal Article Presentation

[Journal Article] Truncated RUNX1 generated from the　fusion of RUNX1 to antisense GRIK2 via a cryptic chromosome translocation enhances　sensitivity　to granulocyte colony-stimulating factor2020
- Author(s)
  Abe A, Yamamoto Y, Katsumi A, Yamamoto H, Okamoto A, Inaguma Y, Iriyama C, Tokuda M, Okamoto M, Emi N, Tomita A.
- Journal Title
  
  Cytogenetic and Genome Research
  
  Volume: - Issue: 5 Pages: 255-263
- DOI
  10.1159/000508012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09860, KAKENHI-PROJECT-19K08853, KAKENHI-PROJECT-18K15402
[Journal Article] Autologous hematopoietic cell transplantation for acute promyelocytic leukemia in second complete remission: outcomes before and after the introduction of arsenic trioxide2017
- Author(s)
  Yanada M, Yano S, Kanamori H, Gotoh M, Emi N, Watakabe K, Kurokawa M, Nishikawa A, Mori T, Tomita N, Murata M, Hashimoto H, Henzan H, Kanda Y, Sawa M, Kohno A, Atsuta Y, Ichinohe T, Takami A
- Journal Title
  
  Leuk Lymphoma
  
  Volume: 58 Issue: 5 Pages: 1061-1067
- DOI
  10.1080/10428194.2016.1231406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09860, KAKENHI-PROJECT-15K09513
[Journal Article] Rearrangement of VPS13B, a causative gene of Cohen syndrome, in a case of RUNX1-RUNX1T1 leukemia with t(8;12;21).2017
- Author(s)
  Abe A, Yamamoto Y, Katsumi A, Okamoto A, Tokuda M, Inaguma Y, Yamamoto K, Yanada M, Kanie T, Tomita A, Akatsuka Y, Okamoto M, Kameyama T, Mayeda A, Emi N.
- Journal Title
  
  Int J Hematol.
  
  Volume: - Issue: 2 Pages: 208-212
- DOI
  10.1007/s12185-017-2387-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09451, KAKENHI-PROJECT-15K09473, KAKENHI-PROJECT-17K07182, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-18K15402, KAKENHI-PROJECT-16K09860
[Journal Article] Current treatment strategies for newly diagnosed and relapsed APL2017
- Author(s)
  Emi N
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 58 Issue: 10 Pages: 1872-1877
- DOI
  10.11406/rinketsu.58.1872
- NAID
  130006132669
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09860
[Journal Article] ETV6-LPXN fusion transcript generated by t(11;12)(q12.1;p13) in a patient with relapsing acute myeloid leukemia with NUP98-HOXA9.2016
- Author(s)
  Abe A, Yamamoto Y, Iba S, Kanie T, Okamoto A, Tokuda M, Inaguma Y, Yanada M, Morishima S, Mizuta S, Akatsuka Y, Okamoto M, Kameyama T, Mayeda A, Emi N.
- Journal Title
  
  Genes, chromosomes & cancer
  
  Volume: 55(3) Issue: 3 Pages: 242-250
- DOI
  10.1002/gcc.22327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430124, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-25461437, KAKENHI-PROJECT-25640081, KAKENHI-PROJECT-24310161, KAKENHI-PROJECT-16K09860
[Journal Article] Transcriptional activation of platelet-derived growth factor receptor α and GS homeobox 2 resulting from E26 transformation-specific variant 6 translocation in a case of acute myeloid leukemia with t(4;12)(q12;p13).2016
- Author(s)
  Abe A, Mizuta S, Okamoto A, Yamamoto Y, Kameyama T, Mayeda A, Emi N.
- Journal Title
  
  International journal of laboratory hematology
  
  Volume: 38(2) Issue: 2 Pages: 15-18
- DOI
  10.1111/ijlh.12450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430124, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-25461437, KAKENHI-PROJECT-25640081, KAKENHI-PROJECT-24310161, KAKENHI-PROJECT-16K09860
[Journal Article] NUP214-RAC1 and RAC1-COL12A1 Fusion in Complex Variant Translocations Involving Chromosomes 6, 7 and 9 in an Acute Myeloid Leukemia Case with DEK-NUP214.2015
- Author(s)
  Abe A, Yamamoto Y, Iba S, Okamoto A, Tokuda M, Inaguma Y, Yanada M, Morishima S, Kanie T, Tsuzuki M, Akatsuka Y, Mizuta S, Okamoto M, Kameyama T, Mayeda A, Emi N.
- Journal Title
  
  Cytogenetic and genome research
  
  Volume: 146(4) Issue: 4 Pages: 279-284
- DOI
  10.1159/000441464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430124, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-25461437, KAKENHI-PROJECT-25640081, KAKENHI-PROJECT-24310161
[Journal Article] Clarifying the Impact of Polycomb Complex Component Disruption in Human Cancers.2014
- Author(s)
  Yamamoto Y, Abe A, Emi N
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 12 Issue: 4 Pages: 479-84
- DOI
  10.1158/1541-7786.mcr-13-0596
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23591410, KAKENHI-PROJECT-25461437
[Journal Article] A varicella outbreak in B-cell lymphoma patients receiving rituximab-containing chemotherapy.2014
- Author(s)
  Okamoto A, Abe A, Okamoto M, Kobayashi T, Inaguma Y, Tokuda M, Yanada M, Morishima S, Kanie T, Yamamoto Y, Tsuzuki M, Mizuta S, Akatsuka Y, Yatsuya H, Yoshikawa T, Emi N.
- Journal Title
  
  J Infect Chemother.
  
  Volume: 20 Issue: 12 Pages: 774-777
- DOI
  10.1016/j.jiac.2014.08.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461437
[Journal Article] Enhancement of transfection activity of lipoplexes by complexation with transferrin-bearing fusogenic polymer-modified liposomes2006
- Author(s)
  N.Sakaguchi, C.Kojima, A.Harada, K.Koiwai, K.Shimizu, N.Emi, K.Kono
- Journal Title
  
  Int.J.Pharmaceutics 325
  
  Pages: 186-190
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300159
[Journal Article] Enhancement of transfection activity of lipoplexes by complexation with transferrin-bearing fusogenic polymer-modified liposomes2006
- Author(s)
  N.Sakaguchi, C.Kojima, A.Harada, K.Koiwai, K.Shimizu, N.Emi, K.Kono
- Journal Title
  
  Int. J. Pharmaceutics 325
  
  Pages: 186-190
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300159
[Journal Article] Preparation of efficient gene carriers using a polyamidoamine dendron-bearing lipid : improvement of serum resistance2005
- Author(s)
  T.Takahashi, A.Harada, N.Emi, K.Kono
- Journal Title
  
  Bioconjugate Chemistry 16
  
  Pages: 1160-1165
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300159
[Presentation] TCF4-MAML3融合遺伝子を認めたCD4+CD56+芽球性NK細胞白血病の１例2019
- Author(s)
  安部明弘、山本幸也、山本秀行、徳田倍将、稲熊容子、岡本晃直、入山智沙子、冨田章裕、岡本昌隆、恵美宣彦
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09860
[Presentation] ETV6の再構成による異所性遺伝子発現を認めた急性骨髄性白血病の二症例2018
- Author(s)
  安部明弘、山本幸也、岡本晃直、入山智沙子、徳田倍将、稲熊容子、蟹江匡治、冨田章裕、赤塚美樹、岡本昌隆、亀山俊樹、前田　明、恵美宣彦
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09860
[Presentation] 再発急性骨髄性白血病において微小転座から複数のスプライシング産物を認めたRUNX1-GRIK2融合遺伝子2017
- Author(s)
  安部明弘、山本幸也、岡本晃直、徳田倍将、稲熊容子、柳田正光、蟹江匡治、冨田章裕、赤塚美樹、岡本昌隆、亀山俊樹、前田明、恵美宣彦
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09860
[Presentation] ETV6転座によるPDGFRαとGSX2の高発現を認めたt(4;12)を有するAMLの一例2016
- Author(s)
  安部明弘、水田秀一、山本幸也、岡本晃直、伊庭佐知子、徳田倍将、稲熊容子、柳田正光、森島聡子、蟹江匡治、富田章裕、赤塚美樹、岡本昌隆、亀山俊樹、前田明、恵美宣彦
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  神奈川県　横浜市　パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K09860
[Presentation] t(8;12;21)(q22:p12;q22)を有するRUNX1-RUNX1T1白血病に認められたTM7SF4-VPS13B融合遺伝子2015
- Author(s)
  安部明弘、山本幸也、岡本晃直、徳田倍将、稲熊容子、山本起代子、柳田正光、森島聡子、蟹江匡治、赤塚美樹、水田秀一、岡本昌1、亀山俊樹２、前田　明、恵美宣彦
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢市
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25461437
[Presentation] DEK-NUP214を有する急性骨髄性白血病に付加的に認められたNUP214-RAC1融合遺伝子
- Author(s)
  安部明弘、恵美宣彦ら
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25461437

1. ABE Akihiro (00432261)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
2. SAITO Hidehiko (20153819)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NAOE Tomoki (50217634)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TANIMOTO Mitune (10240805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KOBAYASHI Masayoshi (60329381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KOMORI Kimihiro (40225587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MUROHARA Toyoaki (90299503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KONO Kenji (90215187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. HARADA Atsush (50302774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. KADOWAKI Norimitsu (60324620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KOJIMA Chie (50405346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. KIYOI Hitoshi (90314004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Mayeda Akila (50212204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. FUKUMURA KAZUHIRO (80622117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 錦見尚道 (40242862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 藤井多久磨 (10218969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 白木良一 (70226330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 山本幸也 (90410703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
19. TUZUKI Sinobu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YOKOZAWA Toshiya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 阿部明弘

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KATSUMI Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 亀山俊樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

NOBUHIKO Emi 恵美 宣彦

EMI Nobuhiko 恵美 宣彦

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of tyrosine kinase chimeric genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of CEV14-PDGFR chimeric genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Truncated RUNX1 generated from the fusion of RUNX1 to antisense GRIK2 via a cryptic chromosome translocation enhances sensitivity to granulocyte colony-stimulating factor2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Autologous hematopoietic cell transplantation for acute promyelocytic leukemia in second complete remission: outcomes before and after the introduction of arsenic trioxide2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rearrangement of VPS13B, a causative gene of Cohen syndrome, in a case of RUNX1-RUNX1T1 leukemia with t(8;12;21).2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Current treatment strategies for newly diagnosed and relapsed APL2017

Author(s)

Journal Title

NOBUHIKO Emi 恵美宣彦

EMI Nobuhiko 恵美宣彦

[Journal Article] Truncated RUNX1 generated from the　fusion of RUNX1 to antisense GRIK2 via a cryptic chromosome translocation enhances　sensitivity　to granulocyte colony-stimulating factor2020