Aratani Yasuaki 荒谷康昭

… Alternative Names

ARATANI YASUAKI 荒谷康昭

ARATANI Yasuaki 荒谷康昭

荒谷康昭アラタニヤスアキ

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Researcher Number	30192470
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 生命ナノシステム科学研究科, 客員教員
Affiliation (based on the past Project Information) *help	2019 – 2023: 横浜市立大学, 理学部, 教授 2016 – 2018: 横浜市立大学, 生命ナノシステム科学研究科(八景キャンパス), 教授 2011 – 2015: 横浜市立大学, 生命ナノシステム科学研究科, 教授 2008: Yokohama City University, 大学院・国際総合科学研究科, 教授 2007 – 2008: Yokohama City University, 国際総合科学研究科, 教授 … More 2005: Yokohama City University, Kihara Institute for Biological Research, Associate Professor, 木原生物学研究所, 準教授 2000 – 2004: 横浜市立大学, 木原生物学研究所, 助教授 2002: Yokohama City University, Kihara Institute for Biological Research, Associate Professor, 付置研究所, 助教授 1998 – 2000: 横浜市立大学, 木原生物学研究所, 助手 1994: 横浜市立大学, 木原生物学研究所, 助手 Less
Review Section/Research Field	Principal Investigator Basic veterinary science/Basic zootechnical science / Basic Section 42030:Animal life science-related / Basic veterinary science/Basic zootechnical science / Integrative animal science / Applied molecular and cellular biology Except Principal Investigator Basic Section 47040:Pharmacology-related / Molecular biology / Experimental pathology / Cell biology
Keywords	Principal Investigator 好中球 / 活性酸素 / ミエロペルオキシダーゼ / 免疫 / 炎症 / reactive oxygen species / neutrophil / NADPHオキシダーゼ / マクロファージ / infectious disease … More / immunology / myeloperoxidase / 感染 / 感染症 / 食細胞NADPHオキシダーゼ / apoptosis / inflammation / infection / アポトーシス / nonhomologous recombination / bleomycin / topoisomerase / gene transfer / mammalian cell / DNA / 非相同的組換え / ブレオマイシン / トポイソメラーゼ / 遺伝子導入 / 動物細胞 / 自然免疫 / 免疫学 / 応用動物 … More Except Principal Investigator SCG / 好中球細胞外トラップ / MPO-ANCA関連血管炎 / Mutation / Checkpoint / Apoptosis / Abnormal neurogenesis / Knockout mouse / DNA repair / DNA polymerase? / 突然変異 / チェックポイント / 細胞死 / 神経発生異常 / ノックアウトマウス / DNA修復 / DNAポリメラーゼβ / KJ MOUSE / POLYMORPHISM OF GENES / CRESENTIC GLOERULONEPHIRITIS / VASCULITIS / ANTI-NEUTROPHIL ANTIBODY MPO-ANCA / NEUTROPHILS / MPO DEFICIENT MOUSE / MYELOPEROXIDASE(MPO) / 自己抗体 / 血管炎発症 / リコンビナント mMPO / Candida albicans / MPO-ANCA / MPO欠損遺伝子 / Myeloperoxidase / Kjマウス / 遺伝子多型 / 半月体形成性糸球体腎炎 / 血管炎 / 好中球抗体MPO-ANCA / 好中球 / MPO遺伝子欠損マウス / ミエロペルオキダーゼ / ジーンターゲテイング / ベクター / トポイソメラーゼ / 組換え / 動物細胞 Less

自然免疫異常マウスの炎症重篤化と血球動態攪乱の発症機構の解明Principal Investigator
- Principal Investigator
  
  荒谷康昭
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Yokohama City University
ROSを介したMPO-ANCA関連腎炎の機序解明と治療薬の検討
- Principal Investigator
  
  山田宗治
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Tokyo Medical University
Mice deficient in NOX2 display severe thymic atrophy and lymphopenia in association with neutrophilic lung inflammationPrincipal Investigator
- Principal Investigator
  
  ARATANI Yasuaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Yokohama City University
Effect of MPO and NOX2 deficiency on sterile inflammation and cytokine expressionPrincipal Investigator
- Principal Investigator
  
  Aratani Yasuaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  Yokohama City University
Myeloperoxidase negatively regulates the expression of proinflammatory cytokines and chemokines by mouse neutrophilsPrincipal Investigator
- Principal Investigator
  
  Aratani Yasuaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  Yokohama City University
Mice deficient in myeloperoxidase and phagocyte NADPH oxidase exacerbates lung inflammation induced by zymosan and nonviable Candida albicansPrincipal Investigator
- Principal Investigator
  
  ARATANI YASUAKI
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Yokohama City University
Myeloperoxidase deficiency induces acute lung inflammationPrincipal Investigator
- Principal Investigator
  
  ARATANI Yasuaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Yokohama City University
Impaired host defense and increased inflammation in mice deficient in myeloperoxidase and NADPH-oxidasePrincipal Investigator
- Principal Investigator
  
  ARATANI Yasuaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Yokohama City University
Impaired host defense in mice deficient in myeloperoxidasePrincipal Investigator
- Principal Investigator
  
  ARATANI Yasuaki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Yokohama City University
Analysis of functions of DNA polymerase? with knockout mice.
- Principal Investigator
  
  KOYAMA Hideki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Yokohama City University
Host Defense and Inflammatory Diseases in Mice Deficient in MyeloperoxidasePrincipal Investigator
- Principal Investigator
  
  ARATANI Yasuaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Yokohama City University
ANALYSIS OF DEVELOPMENT OF MPO-ANCA-RELATED VASCULITIS USING MPO DEFICIENCY
- Principal Investigator
  
  SUZUKI Kazuo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  National Institute of Infections Diseases
Stimulation of gene transfer efficiency by treatment of human cells with topoisomerase II inhibitorsPrincipal Investigator
- Principal Investigator
  
  ARATANI Yasuaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Yokohama City University
哺乳類細胞の組換えにおけるトポイソメラーゼの関与
- Principal Investigator
  
  KOYAMA Hideki
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Yokohama City University

[Book] 好中球機能異常による呼吸器不全-ミエロペルオキシダーゼ欠損を中心に-2008
- Author(s)
  荒谷康昭
- Total Pages
  2
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-19580345
[Book] 好中球機能異常による呼吸器不全-ミエロペルオキシダーゼ欠損を中心に-2008
- Author(s)
  荒谷康昭(分担)
- Publisher
  医学のあゆみ(医歯薬出版)
- Data Source
  KAKENHI-PROJECT-19580345
[Book] ミエロペルオキシダーゼ(MPO)の抗菌活性2007
- Author(s)
  荒谷康昭(分担)
- Publisher
  臨床検査(医学書院)
- Data Source
  KAKENHI-PROJECT-19580345
[Book] 好中球myeloperoxidaseの役割2007
- Author(s)
  荒谷康昭(分担)
- Publisher
  生体防御医学事典(朝倉書店)
- Data Source
  KAKENHI-PROJECT-19580345
[Journal Article] Transcription factor Nrf2 activation regulates NETosis, endothelial injury, and kidney disease in myeloperoxidase-positive antineutrophil cytoplasmic antibody-associated vasculitis.2024
- Author(s)
  Ueda, Y., Nakazawa, D., Nishio, S., Shiratori-Aso, S., Kudo, T., Miyoshi-Harashima, A., Watanabe-Kusunoki, K., Hattanda, F., Iwasaki, S., Tsuji, T., Tomaru, U., Aratani, Y., Yamamoto, M., Ishizu, A., Atsumi, T
- Journal Title
  
  Kidney Int.
  
  Volume: - Issue: 6 Pages: 1291-1305
- DOI
  10.1016/j.kint.2024.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K05593
[Journal Article] PEG-fDAO reduces lung inflammation in gp91-phox knock out chronic granulomatous disease mice following a challenge with non-viable Candida albicans.2022
- Author(s)
  Nunoi, H., Lin, S., Nakamura, H., Aratani, Y., Fang, J., Nishimura, T., Kataoka, H., Maeda, H., Matsukura, M
- Journal Title
  
  Inflammation
  
  Volume: in press Issue: 4 Pages: 1668-1679
- DOI
  10.1007/s10753-022-01650-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06446
[Journal Article] Regulation of NETosis and Inflammation by Cyclophilin D in Myeloperoxidase‐Positive Antineutrophil Cytoplasmic Antibody?Associated Vasculitis2022
- Author(s)
  Kudo Takashi、Nakazawa Daigo、Watanabe‐Kusunoki Kanako、Kanda Masatoshi、Shiratori‐Aso Satoka、Abe Nobuya、Nishio Saori、Koga Jun‐ichiro、Iwasaki Sari、Tsuji Takahiro、Fukasawa Yuichiro、Yamasaki Miwako、Watanabe Masahiko、Masuda Sakiko、Tomaru Utano、Murakami Masaaki、Aratani Yasuaki、Ishizu Akihiro、Atsumi Tatsuya
- Journal Title
  
  Arthritis & Rheumatology
  
  Volume: 75 Issue: 1 Pages: 71-83
- DOI
  10.1002/art.42314
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02958, KAKENHI-PROJECT-20K06446, KAKENHI-PROJECT-20K08581, KAKENHI-PROJECT-23K24099, KAKENHI-PROJECT-22K20908, KAKENHI-PROJECT-20H03410
[Journal Article] Mice deficient in NOX2 display severe thymic atrophy, lymphopenia, and reduced lymphopoiesis in a zymosan-induced model of systemic inflammation.2021
- Author(s)
  Sugimoto, Y., Endo, D., and Aratani, Y.
- Journal Title
  
  Inflammation
  
  Volume: 44 Issue: 1 Pages: 371-382
- DOI
  10.1007/s10753-020-01342-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06446
[Journal Article] Oxidized Phospholipids and Neutrophil Elastase Coordinately Play Critical Roles in NET Formation2021
- Author(s)
  Tokuhiro Takuto、Ishikawa Akane、Sato Haruka、Takita Shunya、Yoshikawa Ayuri、Anzai Ryoko、Sato Shinichi、Aoyagi Ryohei、Arita Makoto、Shibuya Takumi、Aratani Yasuaki、Shimizu Shigeomi、Tanaka Masato、Yotsumoto Satoshi
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 9 Pages: 718586-718586
- DOI
  10.3389/fcell.2021.718586
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-WRAPUP-20H05613, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-21H05029, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20K06446, KAKENHI-PROJECT-21K19387, KAKENHI-PROJECT-20H00467, KAKENHI-PROJECT-20H03473, KAKENHI-PROJECT-19K08894
[Journal Article] Myeloperoxidase: Its role for host defense, inflammation, and neutrophil function2018
- Author(s)
  Aratani Yasuaki
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 640 Pages: 47-52
- DOI
  10.1016/j.abb.2018.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08126
[Journal Article] Genetic phagocyte NADPH-oxidase deficiency enhances nonviable Candida albicans-induced inflammation in mouse lungs.2017
- Author(s)
  Endo, D., Fujimoto, K., Hirose, R., Yamanaka, H., Homme, M., Ishibashi, K., Miura, N., Ohno, N., and Aratani, Y
- Journal Title
  
  Inflammation
  
  Volume: 40 Issue: 1 Pages: 123-135
- DOI
  10.1007/s10753-016-0461-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450446
[Journal Article] Involvement of pentraxin-3 in anti-neutrophil cytoplasmic antibody production induced by aluminum salt adjuvant2017
- Author(s)
  Nagai Kei, Aratani Yasuaki, Shibuya Akira , Yamagata Kunihiro
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: 35 Pages: 735-738
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08126
[Journal Article] The voltage-gated proton channel Hv1/VSOP inhibits neutrophil granule release2016
- Author(s)
  Okochi Y, Aratani Y, Adissu HA, Miyawaki N, Sasaki M, Suzuki K, Okamura Y.
- Journal Title
  
  J Leukoc Biol.
  
  Volume: 99 Issue: 1 Pages: 7-19
- DOI
  10.1189/jlb.3hi0814-393r
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08175, KAKENHI-PROJECT-26450446, KAKENHI-PUBLICLY-26111712, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-25253016, KAKENHI-PROJECT-24590277, KAKENHI-PROJECT-24659268, KAKENHI-PLANNED-15H05901
[Journal Article] Myeloperoxidase deficiency enhances zymosan phagocytosis associated with up-regulation of surface expression of CD11b in mouse neutrophils.2016
- Author(s)
  Fujimoto, K., Motowaki, T., Tamura, N., and Aratani, Y
- Journal Title
  
  Free Radic. Res
  
  Volume: 50 Issue: 12 Pages: 1340-1349
- DOI
  10.1080/10715762.2016.1244821
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450446
[Journal Article] Myeloperoxidase negatively regulates the expression of proinflammatory cytokines and chemokines by zymosan-induced mouse neutrophils.2016
- Author(s)
  Endo, D., Saito, T., Suzuki, K., and Aratani, Y
- Journal Title
  
  Inflamm. Res.
  
  Volume: 65 Issue: 2 Pages: 151-159
- DOI
  10.1007/s00011-015-0899-5
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26450446
[Journal Article] ミエロペルオキシダーゼ欠損と炎症誘発2013
- Author(s)
  荒谷康昭、鈴木和男
- Journal Title
  
  日本臨床
  
  Volume: 71増1 Pages: 258-262
- Data Source
  KAKENHI-PROJECT-23580406
[Journal Article] Myeloperoxidase deficiency induces MIP-2 production via ERK activation in zymosan-stimulated mouse neutrophils.2013
- Author(s)
  Tateno, N., Matsumoto, N., Motowaki, T., Suzuki, K., and Aratani, Y.
- Journal Title
  
  Free Radic. Res.
  
  Volume: 47 Issue: 5 Pages: 376-385
- DOI
  10.3109/10715762.2013.778990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580406, KAKENHI-PROJECT-24659268
[Journal Article] Myeloperoxidase deficiency in mice exacerbates lung inflammation induced by nonviable Candida albicans2013
- Author(s)
  Homme, M., Tateno, N., Miura, N., Ohno, N., and Aratani, Y.
- Journal Title
  
  Inflamm. Res.
  
  Volume: 62 Issue: 11 Pages: 981-990
- DOI
  10.1007/s00011-013-0656-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580406
[Journal Article] The contribution of neutrophil-derived myeloperoxidase in early phase of fulminant acute respiratory distress syndrome induced by influenza virus infection.2012
- Author(s)
  Sugamata, R., Dobashi, H., Nagao, T., Yamamoto, K., Nakajima, N., Sato, Y., Aratani, Y., Oshima, M., Sata, T., Kobayashi, K., Shoji Kawachi, Nakayama, T., and Suzuki, K
- Journal Title
  
  Microbiol. Immunol.
  
  Volume: 56 Pages: 171-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580406
[Journal Article] Role of neutrophil-derived reactive oxygen species for host defense and inflammation2012
- Author(s)
  Aratani Y, Miura N, Ohno N, Suzuki K.
- Journal Title
  
  Med Mycol J
  
  Volume: 53 Pages: 123-128
- NAID
  10031133377
- Data Source
  KAKENHI-PROJECT-23580406
[Journal Article] Myeloperoxidase exacerbates secondary injury by generating highly reactive oxygen species and mediating neutrophils recruitment in experimental spinal cord injury2012
- Author(s)
  Kubota K, Sawai H, kumamaru H, Maeda T, Ohkawa Y, Aratani Y, Nagano T, Urano Y, Iwamoto Y, Okada S
- Journal Title
  
  Spine
  
  Volume: 37 Issue: 16 Pages: 1363-9
- DOI
  10.1097/brs.0b013e31824b9e77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390292, KAKENHI-PROJECT-23580406, KAKENHI-PROJECT-23650327, KAKENHI-PUBLICLY-23123516
[Journal Article] Severe neutrophil-mediated lung inflammation in myeloperoxidase-deficient mice exposed to zymosan.2012
- Author(s)
  Takeuchi, K., Umeki, Y., Matsumoto, N., Yamamoto, K., Yoshida, M., Suzuki, K., and Aratani, Y
- Journal Title
  
  Inflamm. Res.
  
  Volume: 61 Pages: 197-205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580406
[Journal Article] Direct activation of glomerular endothelial cells by anti-moesin activity of anti-myeloperoxidase antibody.2011
- Author(s)
  Nagao, T., Suzuki, K., Utsunomiya, K., Matsumura, M., Saiga, K., Wang, P., Minamitani, H., Aratani, Y., Nakayama, T., Suzuki, K
- Journal Title
  
  Nephrol. Dial. Transplant.
  
  Volume: 26 Pages: 2752-2760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580406
[Journal Article] Key role of RANTES (regulated upon activation normal T-cell expressed and secreted), nonstructural protein1 and myeloperoxidase in cytokine storm induced by influenza virus PR-8 (A/H1N1) infection in A549 bronchial epithelial cells.2011
- Author(s)
  Phung, T., Sugamata, R., Uno K. Aratani, Y., Ozato, K., Kawachi, S., Nguyen, L., Nakayama, T., and Suzuki, K
- Journal Title
  
  Microbiol. Immunol.
  
  Volume: 55 Pages: 874-884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580406
[Journal Article] Development of thermotolerance requires interaction between polymerase βand heat shock proteins.2008
- Author(s)
  Takahashi, A., Yamakawa, N., Mori, E., Ohnishi, K., Yokota, S., Sugo, N., Aratani, Y., Kovama, H., Ohnishi T
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 973-978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580345
[Journal Article] Activation of Inducible Nitric Oxide Synthase Increases MMP-2 and MMP-9 Levels in ApoE-knockout Mice2008
- Author(s)
  Chen, Y., Aratani, Y., Osawa, T., Fukuyama, N., and Nakazawa, H.
- Journal Title
  
  Tokai J. Exp. Clin. Med. 33
  
  Pages: 28-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580345
[Journal Article] Development of thermotolerance requires interaction between polymerase β and heat shock proteins2008
- Author(s)
  Takahashi, A., Yamakawa, N., Mori, E., Ohnishi, K., Yokota, S., Sugo, N., Aratani, Y., Koyama, H., Ohnishi, T
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 973-978
- NAID
  10024006163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580345
[Journal Article] Activation of Inducible Nitric Oxide Synthase Increases MMP-2 and MMP-9 Levels in ApoE-knockout Mice.2008
- Author(s)
  Chen, Y., Aratani, Y., Osawa, T., Fukuyama, N., Nakazawa, H
- Journal Title
  
  Tokai J. Exp. Clin. Med. 33
  
  Pages: 28-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580345
[Journal Article] Myeloperoxidase is critically involved in the induction of organ damage following renal ischemia reperfusion2007
- Author(s)
  Matthijsen, R.A., Huugen, D., Hoebers, N.T., Vries, B., Peutz-Kootstra, C. J., Aratani, Y., Daha, M.R., Tervaert, J. W. C., Buurman, W. A., and Heeringa, P.
- Journal Title
  
  Am. J. Pathol. 171
  
  Pages: 1743-1752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580345
[Journal Article] Decreased PARP-1 levels accelerate embryonic lethality but attenuate neuronal apoptosis in DNA polymerase β-deficient mice. Biochem2007
- Author(s)
  Sugo, N., Niimi, N., Aratani, Y., Masutani, M., Suzuki, H., and Koyama, H
- Journal Title
  
  Biophys. Res. Commun. 345
  
  Pages: 656-661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580345
[Journal Article] Myeloperoxidase is critically involved in the induction of organ damage following renal ischemia reperfusion2007
- Author(s)
  荒谷康昭, 他9名
- Journal Title
  
  Am. J. Pathol 171
  
  Pages: 1743-1752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580345
[Journal Article] Pregnancy Promotes Myeloperoxidase Accumulation at the Cell Surface and Enhances Cell Metabolism and Oxidant Release by Maternal Neutrophils.2006
- Author(s)
  Kindzelskii, A.L., Clark, A.J., Espinoza, J., Maeda, N., Aratani, Y., Romero, R., Petty, A.R
- Journal Title
  
  Eur.J.Immunol. 10
  
  Pages: 1619-1628
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580243
[Journal Article] Interferon-g Primes RAW264 Macrophages and Human Monocytes for Enhanced Oxidant Production in Response to CpG DNA via Metabolic Signaling : Roles of TLR9 and Myeloperoxidase Trafficking.2006
- Author(s)
  Adachi, Y, Kindzelskii, A.L., Petty, A.R., Huang, J., Maeda, N., Aratani, Y., Ohno, K., Petty, A.R
- Journal Title
  
  J.Immunol. 176
  
  Pages: 5033-5040
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580243
[Journal Article] Contribution of the myeloperoxidase-dependent oxidative system to host defense against Cryptococcus neoformans.2006
- Author(s)
  Aratani, Y.
- Journal Title
  
  J. Med. Microbiol. (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580243
[Journal Article] Contribution of the myeloperoxidase-dependent oxidative system to host defense against Cryptococcus neoformans.2006
- Author(s)
  Aratani, Y., Kura, F., Watanabe, H., Akagawa, H., Takano, Y., Ishida-Okawara, A., Suzuki, K., Maeda, N., Koyama, H
- Journal Title
  
  J.Med.Microbiol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580243
[Journal Article] Earlier onset of neutrophil-mediated inflammation in the ultraviolet-exposed skin of mice deficient in myeloperoxidase and NADPH oxidase.2006
- Author(s)
  Komatsu, J., Koyama, H., Maeda, N., Aratani, Y
- Journal Title
  
  Inflamm.Res. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580243
[Journal Article] Genetic interaction between DNA polymerase beta and DNA-PKcs in embryogenesis and neurogenesis.2005
- Author(s)
  Niimi, N., Sugo, N., Aratani, Y., Koyama, H
- Journal Title
  
  Cell Death Differ 12
  
  Pages: 184-191
- Data Source
  KAKENHI-PROJECT-16580243
[Journal Article] Phorbol myristate acetate induces neutrophil death through activation of p38 mitogen-activated protein kinase that requires endogenous reactive oxygen species other than HOCl.2005
- Author(s)
  Saito, T., Takahashi, H., Doken, H., Koyama, H., Aratani, Y
- Journal Title
  
  Biosci.Biotech.Biochem. 69
  
  Pages: 2207-2212
- NAID
  130000030496
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580243
[Journal Article] p53 deficiency rescues neuronal apoptosis but not differentiation in DNA polymerase b-deficient mice.2004
- Author(s)
  Sugo, N., Niimi, N., Aratani, Y., Takiguchi-Hahashi, K., Koyama, H
- Journal Title
  
  Mol.Cell Biol 24
  
  Pages: 9470-9477
- Data Source
  KAKENHI-PROJECT-16580243
[Journal Article] In vivo role of myeloperoxidase for the host defense.2004
- Author(s)
  Aratani.Y., et al., K.
- Journal Title
  
  Jpn J Infect Dis. 57
- Data Source
  KAKENHI-PROJECT-16580243
[Journal Article] In vivo role of myeloperoxidase for the host defense.2004
- Author(s)
  Aratani, Y., Kura, F., Watanabe, H., Akagawa, H., Takano, Y., Suzuki, K., Dinauer, M.C., Maeda, N., Koyama, H
- Journal Title
  
  Jpn.J.Infect.Dis. 57
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580243
[Journal Article] In vivo role of myeloperoxidase for the host defense.2004
- Author(s)
  Aratani. Y.
- Journal Title
  
  Jpn J Infect Dis. 57
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580243
[Presentation] ミエロペルオキシダーゼ欠損マウスにおけるザイモザン誘発性肺炎に伴うG-CSFの過剰産生2023
- Author(s)
  佐藤勇樹、吉川美佐紀、荒谷康昭
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K05593
[Presentation] ミエロペルオキシダーゼ欠損マウスのザイモザン誘発性肺炎に伴う造血異常の機構解析2023
- Author(s)
  吉川美佐紀、佐藤勇樹、荒谷康昭
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K05593
[Presentation] Mice deficient in NOX2 and MPO display an enhanced granulopoiesis and reduced lymphopoiesis in a zymosan-induced inflammation model.2023
- Author(s)
  Aratani, Y., Endo, D., Yamanaka, H., and Sugimoto, Y
- Organizer
  12th International Human Peroxidase Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05593
[Presentation] 食細胞NADPHオキシダーゼ欠損マウスはザイモザンの全身投与によってリンパ球減少症を発症する。2020
- Author(s)
  杉本　遊、荒谷康昭
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06446
[Presentation] NADPH-oxidase deficiency enhances nonviable Candida albicans-induced lung inflammation.2019
- Author(s)
  Aratani, Y., Endo, D., Yamanaka, H., Sugimoto, Y., Tomimoto, Y., and Ohno, N
- Organizer
  12th International human Peroxidase Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08126
[Presentation] MPO欠損とNOX2欠損による非感染性炎症の誘発とサイトカイン過剰産生2019
- Author(s)
  荒谷康昭
- Organizer
  第25回MPO研究会
- Data Source
  KAKENHI-PROJECT-17K08126
[Presentation] ザイモザン刺激によるミエロペルオキシダーゼ欠損好中球からのMIP-2過剰産生機構の解析2019
- Author(s)
  杉本　遊、高取沙織、荒谷康昭
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08126
[Presentation] 食細胞NADPHオキシダーゼ欠損マクロファージからのKC過剰産生におけるNrf2の関与2018
- Author(s)
  遠藤大樹、富本勇樹、荒谷康昭
- Organizer
  第24回MPO研究会
- Data Source
  KAKENHI-PROJECT-17K08126
[Presentation] ミエロペルオキシダーゼ欠損マウスにおけるzymosan誘発性脾臓炎症の重篤化2018
- Author(s)
  杉本　遊、荒谷康昭
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08126
[Presentation] 野生型およびミエロペルオキシダーゼ欠損好中球からのMIP-2産生におけるTLR2の関与2018
- Author(s)
  髙取沙織、荒谷康昭
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08126
[Presentation] 野生型およびミエロペルオキシダーゼ欠損好中球のサイトカイン産生に及ぼすビタミンCの影響2018
- Author(s)
  髙取沙織、荒谷康昭
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-17K08126
[Presentation] 食細胞NADPHオキシダーゼ欠損マクロファージにおけるKC過剰産生機構の解析2018
- Author(s)
  富本勇樹、遠藤大樹、荒谷康昭
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08126
[Presentation] Myeloperoxidase deficiency enhances phagocytosis associated with up-regulation of surface expression of CD11b.2017
- Author(s)
  Fujimoto K.,Motowaki T., Tamura N., and Aratani Y.
- Organizer
  18th International Vasculitis & ANCA Workshop
- Place of Presentation
  東京
- Year and Date
  2017-03-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] ミエロペルオキシダーゼ欠損好中球における貪食能の亢進に伴うMIP-2の過剰産生2017
- Author(s)
  髙取沙織、荒谷康昭
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08126
[Presentation] アルミニウムゲル投与によるマウスMPO-ANCA産生モデルの樹立2017
- Author(s)
  永井恵、荒谷康昭、山縣邦弘
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08126
[Presentation] Myeloperoxidase deficiency enhances zymosan phagocytosis in mouse neutrophils2017
- Author(s)
  Aratani Yasuaki, Fujimoto Kenta, Motowaki, Takehiro, Tamura Naoya
- Organizer
  10th International human Peroxidase Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08126
[Presentation] A evidence for regulation by pentatraxin 3 in production of murine anti-myeloperoxidase antibody in vivo2017
- Author(s)
  Kei Nagai, Yasuaki Aratani, Kunihiro Yamagata
- Organizer
  第54回欧州腎臓学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08126
[Presentation] MPO欠損に伴うマウス好中球のzymosan貪食能亢進機構の解析2017
- Author(s)
  荒谷康昭、藤本健太
- Organizer
  第23回MPO研究会
- Data Source
  KAKENHI-PROJECT-17K08126
[Presentation] ミエロペルオキシダーゼ欠損好中球における貪食活性促進機構の解析2016
- Author(s)
  藤本健太、荒谷康昭
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] 好中球のザイモザン貪食能におけるミエロペルオキシダーゼの役割2016
- Author(s)
  藤本健太、荒谷康昭
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] 野生型およびミエロペルオキシダーゼ欠損好中球からのMIP-2産生に及ぼすビタミンCの影響2016
- Author(s)
  髙取沙織、荒谷康昭
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] 好中球からのサイトカイン産生におけるミエロペルオキシダーゼの役割2016
- Author(s)
  遠藤大樹、荒谷康昭
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] 食細胞NADPHオキシダーゼ欠損によるカンジダ死菌誘発性肺炎の重篤化2016
- Author(s)
  遠藤大樹、藤本健太、石橋健一、三浦典子、大野尚仁、荒谷康昭
- Organizer
  第22回MPO研究会
- Place of Presentation
  京都
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] 食細胞NADPHオキシダーゼ欠損好中球におけるIL-1β過剰産生機構の解析2016
- Author(s)
  遠藤大樹、山中寛子、廣瀬理華、藤本健太、高取沙織、荒谷康昭
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] ミエロペルオキシダーゼ欠損好中球における貪食能の解析2015
- Author(s)
  藤本健太、本脇献浩、荒谷康昭
- Organizer
  第26回日本生体防御学会学術総会
- Place of Presentation
  東京
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] MPO欠損マウス好中球からの炎症性サイトカイン過剰産生による肺炎の誘発2015
- Author(s)
  荒谷康昭、遠藤大樹、鈴木和男
- Organizer
  第20回 MPO研究会
- Place of Presentation
  東京
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] ミエロペルオキシダーゼ欠損好中球によるサイトカイン過剰産生機構の解析2015
- Author(s)
  遠藤大樹、齊藤誉幸、荒谷康昭
- Organizer
  第26回日本生体防御学会学術総会
- Place of Presentation
  東京
- Year and Date
  2015-07-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] 食細胞NADPHオキシダーゼ欠損マウスにおけるカンジダ死菌誘発性肺炎の解析2015
- Author(s)
  廣瀬理華、山中寛子、本目みずき、石橋健一、三浦典子、大野尚仁、荒谷康昭
- Organizer
  第26回日本生体防御学会学術総会
- Place of Presentation
  東京
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] Voltage-gated proton channel Hv1/VSOP inhibits granule exocytosis in neutrophils and inflammation.2015
- Author(s)
  Okochi, Y., Aratani, Y., Adissu, H., Miyawaki, N., Sasaki, M., Suzuki, K., and Okamura, Y
- Organizer
  8th FAOPS Congress
- Place of Presentation
  Bangkok(Thailand)
- Year and Date
  2015-11-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] Aberrant production of inflammatory mediators in myeloperoxidase-deficient neutrophils stimulated with zymosan.2015
- Author(s)
  Endo, D., Fujimoto, K., Saito, T., Motowaki, T., and Aratani, Y
- Organizer
  9th International human Peroxidase Meeting
- Place of Presentation
  Cologne(Germany)
- Year and Date
  2015-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] Hv1/VSOP voltage-gated proton channels inhibit neutrophil granule release and inflammation.2013
- Author(s)
  Okochi,Y., Aratani, Y., Adissu, H., Miyawaki, N., Sasaki, M., Suzuki, K., and Okamura, Y
- Organizer
  第2回多階層生体機能学HD Physiology 国際シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] 電位依存性プロトンチャネルHv1/VSOPは好中球の顆粒放出と炎症を抑制する2013
- Author(s)
  大河内善史、荒谷康昭、Hibret A. Adissu、宮脇奈那、佐々木真理、鈴木和男、岡村康司
- Organizer
  第19回MPO研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] Myeloperoxidase deficiency induces MIP-2 production via ERK activation in mouse neutrophils stimulated with zymosan.2013
- Author(s)
  Aratani, Y., Tateno, N., Matsumoto, N., Motowaki, T., and Suzuki, K
- Organizer
  8th International human Peroxidase Meeting
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] ミエロペルオキシターゼ欠損好中球における貪食活性の促進2013
- Author(s)
  田村直也、荒谷康昭
- Organizer
  第36回　日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] 好中球ミエロペルオキシダーゼ欠損によるカンジダ死菌誘発性肺炎重篤化2013
- Author(s)
  本目みずき、舘野奈央、三浦典子、大野尚仁、荒谷康昭
- Organizer
  第36回　日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] 好中球からのMIP-2産生におけるMPO欠損の影響2013
- Author(s)
  荒谷康昭、舘野奈央、松本典子、本脇献浩、鈴木和男
- Organizer
  第19回MPO研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] ミエロペルオキシダーゼ欠損好中球のMIP-2過剰産生機構の解析2013
- Author(s)
  荒谷康昭、舘野奈央、松本典子、本脇献浩、鈴木和男
- Organizer
  第24回日本生体防御学会学術総会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] 好中球のMIP-2産生におけるミエロペルオキシダーゼの役割2012
- Author(s)
  舘野奈央、松本典子、荒谷康昭
- Organizer
  第23回日本生体防御学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] ミエロペルオキシダーゼ欠損マウスのカンジダ死菌誘発性肺炎重篤化2012
- Author(s)
  本目みずき、三浦典子、大野尚仁、荒谷康昭
- Organizer
  第35回　日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] ミエロペルオキシダーゼ欠損マウスにおけるカンジダ死菌誘発性肺炎の解析2012
- Author(s)
  本目みずき、舘野奈央、三浦典子、大野尚仁、荒谷康昭
- Organizer
  第23回日本生体防御学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] Myeloperoxidase deficiency enhances lung inflammation in mice exposed to zymosan.2012
- Author(s)
  Takeuchi, K., Umeki, Y., Matsumoto, N., Yamamoto, K., Yoshida, M., Suzuki, K., and Aratani, Y
- Organizer
  The Asia Pacific Meeting of Vasculitis and ANCA Workshop 2012
- Place of Presentation
  Tokyo (Tokyo conference center shinagawa)
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] 好中球からのMIP-2産生におけるミエロペルオキシダーゼ欠損の影響2012
- Author(s)
  舘野奈央、松本典子、本脇献浩、荒谷康昭
- Organizer
  第18回MPO研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] Key role of RANTES, NS1 and MPO in cytokine storm induced by influenza virus infection in A549 bronchial epithelial cells.2012
- Author(s)
  Phung, T., Sugamata, R., Uno K. Aratani, Y., Ozato, K., Kawachi, S., Nguyen, L., Nakayama, T., and Suzuki, K
- Organizer
  The Asia Pacific Meeting of Vasculitis and ANCA Workshop 2012
- Place of Presentation
  Tokyo (Tokyo conference center shinagawa)
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] ミエロペルオキシダーゼ欠損好中球のMIP-2過剰産生の機序2012
- Author(s)
  舘野奈央、松本典子、荒谷康昭
- Organizer
  第35回　日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] The role of voltage-gated proton channel VSOP in host defense against pathogen.2012
- Author(s)
  Yoshifumi Okochi, Y., Aratani, Y., Suzuki, K., Miyawaki, N., Sasaki, M., Okamura, Y
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野(松本文化会館）
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] 劇症型ARDSのインフルエンザウイルスNS1とMPOが連続するcytokine-chemokine誘導の亢進はサイトカインストームに貢献している。2011
- Author(s)
  Phung, T.,菅又龍一、宇野加津子、荒谷康昭、Ozato, K.,河内正治、Nyuyen, L.、中山俊憲、鈴木和男
- Organizer
  第17回MPO研究会
- Place of Presentation
  熊本(アークホテル熊本）
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] Severe lung inflammation in myeloperoxidase- and phagocyte NADPH-oxidase-deficient mice expose to sterilized Candida albicans.2011
- Author(s)
  Honme, M., Sugimura, M., Tateno, N., Miura, N., Ohno, N., and Aratani, Y
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜(パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] 真菌感染防御における好中球由来の活性酸素の役割。2011
- Author(s)
  荒谷康昭、三浦典子、大野尚仁、鈴木和男
- Organizer
  第55回日本医真菌学会学術集会(招待講演)
- Place of Presentation
  東京（椿山荘東京）
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] ミエロペルオキシダーゼ欠損マウスのカンジダ死菌による肺炎の重篤化。2011
- Author(s)
  荒谷康昭、本目みずき、三浦典子、大野尚仁
- Organizer
  第17回MPO研究会
- Place of Presentation
  熊本(アークホテル熊本）
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] ミエロペルオキシダーゼ欠損マウスのザイモザン誘発性肺炎の促進2009
- Author(s)
  荒谷康昭、梅木佑、西川なつき、戸塚彩子、吉田后那、鈴木和男
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19580345
[Presentation] Myeloperoxidase deficiency promotes zymosan-induced acute lung inflammation2008
- Author(s)
  Umeki Y., Nishikawa N., Suzuki K., Aratani Y.
- Organizer
  第38回日本免疫学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19580345
[Presentation] Secretion of neutrophil chemotactic factors from glomerular endothelial cells by anti-myeloperoxidase antibody2008
- Author(s)
  Nagao T., Aratani Y., Nakayama T., Suzuki K
- Organizer
  第38回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19580345
[Presentation] Phagocyte NADPH-oxidase deficiency promotes zymosan-induced acute lung inflammation2008
- Author(s)
  Nishikawa N., Umeki Y., Aratani Y.
- Organizer
  第38回日本免疫学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19580345
[Presentation] MPO-ANCAによる糸球体血管内皮細胞の好中球走化性因子の発現2008
- Author(s)
  長尾朋和、松村実美子、荒谷康昭、中山俊憲、南谷晴之、鈴木和男
- Organizer
  第14回MPO研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19580345
[Presentation] Zymosan誘発性肺炎におけるMyeloperoxidaseの役割2008
- Author(s)
  梅木祐、瀬田玄樹、西川なつき、鈴木和男、荒谷康昭
- Organizer
  第14回MPO研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19580345
[Presentation] Secretion of neutrophil chemotactic factors from glomerular endothelial cells by anti- myeloperoxidase antibody2008
- Author(s)
  Nagao T., Aratani Y., Nakayama T., Suzuki K.
- Organizer
  第38回日本免疫学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19580345
[Presentation] Contribution of myeloperoxidase to host defense against pulmonary and systemic infections with Cryptococcus neoformans2007
- Author(s)
  Aratani, Y., Kura, F., Watanabe, H., Takano, Y., Okawara, A., Suzuki, K., Maeda, N., and Koyama, H
- Organizer
  The 5th international Peroxidase Meeting
- Place of Presentation
  New Zealand
- Data Source
  KAKENHI-PROJECT-19580345
[Presentation] ミエロペルオキシダーゼ欠損マウスのザイモザンによる肺炎の誘発2007
- Author(s)
  荒谷康昭、瀬田玄樹、梅木祐、西川なつき、鈴木和男
- Organizer
  第13回MPO研究会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-19580345
[Presentation] MPO-ANCAによる糸球体内皮細胞の活性化2007
- Author(s)
  長尾朋和、松村実美子、荒谷康昭、星野昭芳、山本健二、中山俊憲、南谷晴之、鈴木和男
- Organizer
  第13回MPO研究会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-19580345
[Presentation] 食細胞NADPHオキシダーゼ欠損マウスにおけるカンジダ死菌誘発性肺炎の解析
- Author(s)
  廣瀬理華、山中寛子、本目みずき、石橋健一、三浦典子、大野尚仁、荒谷康昭
- Organizer
  第26回日本生体防御学会学術総会
- Place of Presentation
  台東区生涯学習センター（東京都台東区）
- Year and Date
  2015-07-10 – 2015-07-12
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] ミエロペルオキシダーゼ欠損マウスのカンジダ死菌肺炎重篤化機構
- Author(s)
  荒谷康昭、本目みずき、三浦典子、大野尚仁
- Organizer
  第25回日本生体防御学会学術総会
- Place of Presentation
  仙台市
- Year and Date
  2014-07-09 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] ミエロペルオキシダーゼ欠損マウスのカンジダ死菌肺炎重篤化機構
- Author(s)
  荒谷康昭、本目みずき、三浦典子、大野尚仁
- Organizer
  第25回日本生体防御学会学術総会
- Place of Presentation
  東北大学（宮城県仙台市）
- Year and Date
  2014-07-09 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] ミエロペルオキシダーゼ欠損好中球における貪食能の解析
- Author(s)
  藤本健太、本脇献浩、荒谷康昭
- Organizer
  第26回日本生体防御学会学術総会
- Place of Presentation
  台東区生涯学習センター（東京都台東区）
- Year and Date
  2015-07-10 – 2015-07-12
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] Myeloperoxidase deficiency enhances MIP-2 expression in mouse neutrophils exposed to zymosan.
- Author(s)
  Matsumoto, N., Yamamoto, K., and Aratani, Y
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜(パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] ミエロペルオキシダーゼ欠損好中球によるサイトカイン過剰産生機構の解析
- Author(s)
  遠藤大樹、齊藤誉幸、荒谷康昭
- Organizer
  第26回日本生体防御学会学術総会
- Place of Presentation
  台東区生涯学習センター（東京都台東区）
- Year and Date
  2015-07-10 – 2015-07-12
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] ミエロペルオキシダーゼ欠損好中球におけるザイモザン貪食能の促進
- Author(s)
  本脇献浩、藤本健太、荒谷康昭
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] ミエロペルオキシダーゼ欠損による好中球からのサイトカイン過剰産生
- Author(s)
  齊藤誉幸、遠藤大樹、荒谷康昭
- Organizer
  第20回 MPO研究会
- Place of Presentation
  KKRホテル熱海（静岡県熱海市）
- Year and Date
  2014-11-07 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-26450446
[Presentation] Severe neutrophil-mediated lung inflammation in myeloperoxidase-deficient mice exposed to zymosan.
- Author(s)
  Kazuhiro Takeuchi, K., Umeki, Y., Matsumoto, N., Yamamoto, K., Yoshida, M., Suzuki, K., and Aratani, Y
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜(パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] Phagocyte NADPH-oxidase regulates zymosan induced acute lung inflammation.
- Author(s)
  Tateno, N., Nishikawa, N., Honme, M., and Aratani, Y
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜(パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-23580406
[Presentation] ミエロペルオキシダーゼ欠損好中球におけるサイトカイン発現量の促進
- Author(s)
  齊藤誉幸、遠藤大樹、荒谷康昭
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26450446
[]

1. KOYAMA Hideki (40085626)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
2. SUZUKI Kazuo (20192130)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KURA Fumiaki (30161722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKAHASHI Kei (80216712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OKAWARA Akiko (30260277)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山田宗治 (10625164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 尾田高志 (90531187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 内田貴大 (90865627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 瀬田玄樹

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 梅木佑

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. 西川なつき

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. 戸塚彩子

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 吉田后那

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 車

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 軒

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Okamura Yasushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. OKADA Seiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. OHKAWA Yasuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 大河内善史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 石津明洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 外丸詩野

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 中沢大悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 益田紗季子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 有田誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Aratani Yasuaki 荒谷 康昭

ARATANI YASUAKI 荒谷 康昭

ARATANI Yasuaki 荒谷 康昭

荒谷 康昭 アラタニ ヤスアキ

Research Projects

Research Products

Co-Researchers

自然免疫異常マウスの炎症重篤化と血球動態攪乱の発症機構の解明Principal Investigator

Principal Investigator

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Review Section

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ROSを介したMPO-ANCA関連腎炎の機序解明と治療薬の検討

Principal Investigator

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Review Section

Research Institution

Mice deficient in NOX2 display severe thymic atrophy and lymphopenia in association with neutrophilic lung inflammationPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Effect of MPO and NOX2 deficiency on sterile inflammation and cytokine expressionPrincipal Investigator

Principal Investigator

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Research Institution

Myeloperoxidase negatively regulates the expression of proinflammatory cytokines and chemokines by mouse neutrophilsPrincipal Investigator

Principal Investigator

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Research Institution

Mice deficient in myeloperoxidase and phagocyte NADPH oxidase exacerbates lung inflammation induced by zymosan and nonviable Candida albicansPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Myeloperoxidase deficiency induces acute lung inflammationPrincipal Investigator

Principal Investigator

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Research Category

Research Field

Research Institution

Impaired host defense and increased inflammation in mice deficient in myeloperoxidase and NADPH-oxidasePrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Impaired host defense in mice deficient in myeloperoxidasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of functions of DNA polymerase? with knockout mice.

Principal Investigator

Project Period (FY)

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Research Institution

Host Defense and Inflammatory Diseases in Mice Deficient in MyeloperoxidasePrincipal Investigator

Principal Investigator

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Research Institution

ANALYSIS OF DEVELOPMENT OF MPO-ANCA-RELATED VASCULITIS USING MPO DEFICIENCY

Principal Investigator

Project Period (FY)

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Research Institution

Stimulation of gene transfer efficiency by treatment of human cells with topoisomerase II inhibitorsPrincipal Investigator

Aratani Yasuaki 荒谷康昭

ARATANI YASUAKI 荒谷康昭

ARATANI Yasuaki 荒谷康昭

荒谷康昭アラタニヤスアキ