• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

SEKI George  関 常司

ORCIDConnect your ORCID iD *help
Researcher Number 30206619
External Links
Affiliation (based on the past Project Information) *help 2008 – 2015: The University of Tokyo, 医学部附属病院, 講師
2013: 東京大学, 医学部, 講師
2010: 東京大学, 医学部・附属病院, 講師
2007 – 2008: The University of Tokyo, 医学部・附属病院, 講師
2005: 東京大学, 医学部・附属病院, 講師 … More
2003 – 2005: The University of Tokyo, Urology, Assistant Professor, 医学部附属病院, 講師
2002 – 2003: 東京大学, 医学部附属病院, 助手
2002: Tokyo University, hospitals in affiliation with medicine, Speaker, Assistant, 医学部(附属病院), 助手
2000 – 2001: 東京大学, 医学部・附属病院, 助手
1998: University of Tokyo, Dept. Medicine Assit, Professor., 医学部・附属病院, 助手
1996 – 1997: 東京大学, 医学部附属病院, 助手
1996: University of Tokyo, Faculty of medicine, Assistant Professor, 医学部・附属病院, 助手
1995: 東京大学, 医学部(病), 医員
1994 – 1995: 東京大学, 医学部(病), 助手
1993: 東京大学, 医学部, 助手
1992 – 1993: 東京大学, 医学部(病), 医員 Less
Review Section/Research Field
Principal Investigator
Kidney internal medicine / Kidney internal medicine
Except Principal Investigator
Kidney internal medicine / Kidney internal medicine / 内科学一般 / Urology / Urology / Ophthalmology / General pharmacology / Neurology / Circulatory organs internal medicine
Keywords
Principal Investigator
RTA / NBC1 / 近位尿細管性アシドーシス / ERK / 近位尿細管 / glaucoma / NBC-1 / イオン輸送 / Edema / Thiazolidinediones … More / PPARγ / 浮腫 / チアゾリジン系薬剤 / cancer metastasis / electrophysiology / bicarbonate absorption / pancreatic secretion / pRTA / stoichiometry / HCO3 / NBC / 腎癌転移 / 電気生理学 / 重炭酸再吸収 / 膵液分泌 / band keratepathy / Cataracts / 帯状角膜変性症 / 緑内障 / 白内障 / ナトリウム重炭酸共輸送体 / hand keratopathy / hand keratopaty / cataracts / organic acid traxsporter / proton secretion / ion transport / renal proximal tubule / 腎生理学 / ナトリウムイオン / 酸分泌 / 有機酸輸送体 / 酸分泌機構 / H-ATPase / CLC5 / Dent病 / PTC124 / W516Xノックインマウス / 近位尿細管アシドーシス / NBCe1 / cPLA2 / 腎近位尿細管 / PLA2 / アンジオテンシンII / プロテインキナーゼC / 細胞内カルシウム / ATP受容体 … More
Except Principal Investigator
RT-PCR / 高血圧 / 近位尿細管 / mRNA / メサンギウム細胞 / NBC1 / NBCe1 / SLC4A4 / Na-HCO_3共輸送体 / NBC-1 / microdissection / ネフロン / platelet activating factor / mesangial cells / クロライド / エンドセリン / 血小板活性化因子 / 細胞内pH / IRBIT / 片頭痛 / anti NBC1 ribozime / inhibitors of NBC1 / motility of the RCC cells / Na-HCO_3-cotransporter / renal cell carcinoma / kidney / 腎癌細胞転移 / 抗NBC1リボザイム(Rz-NBC1) / NBC1特異的阻害剤(S0859) / 抗NBC1リボザイム / NBC1特異的阻害剤 / 細胞株遊走能 / 腎癌 / 正常腎 / Xenopus oocyte / renal tubular acidosis / Na-HCO3-cotransporter / renal tubules / ヒト腎癌細胞 / ヒト正常腎尿細管 / アフリカツメガエル卵母細胞 / 腎尿細管性アシドーシス / 正常腎尿細管 / Glaucoma / Cataract / band keratopathy / 帯状角膜変性症 / 緑内障 / 白内障 / homologous down-regulation / glomerular mesangial cells / mRNA expression / nephron / thromboxane A_2 receptor / platelet-activating factor receptor / 遺伝子多型 / 情報伝達 / mRNA定量 / micro-perfusion / MRT-PCR / プロスタグランジン / 血小板活性化因子(PAF) / down-regulation / トロンボキサン受容体 / 血小板活性化因子受容体 / prostaglandin / tubular function / Ca signal / chloride / insulin like growth factor-I (IGF-I) / hypertension / β-レセプター / H-antiporter / Na / 副甲状腺ホルモン関連ペプチド(PTHrP) / 微量循環法 / TGF / アンチセンス / Na-H輸送体 / クロライドチャネル / 糸球体メサンギウム細胞 / 副甲状腺関連ペプチド(PTHrP) / 尿細管糸状体フィードバック / インスリン様成長因子(IGF-I) / 糸球体機能 / プロスタグラレディン / 尿細管機能 / Caシグナル / クロライド(Cl) / インスリン様成長因子(IGF)-I / tubule microperfusion / monoclonal antibody / receptor / 分子生物学 / カルシウムイオン / 腎尿細管 / 腎糸球体 / 血小位板活性化因子 / 尿細管微小還流 / 単クローン抗体 / RT-PCR法 / 受容体 / tubulo-glomerular feedback / calcium / endothelin / transforming growth factor beta (TGF-beta) / 細胞内Caイオン / Cーkinase / 皮質集合管 / アルギニンーバソプレッシン / 不活性型 / PAF(血小板刺激因子) / レセプタ- / PCR / エンドセリンーI / TGFーβ / ホルモンレセプター / 副甲状腺ホルモン / プロスタグランディン / バゾプレッシン / 尿細管糸球体フィードバック / カルシウム / 形質転換成長因子ーβ / 尿細管 / Na輸送 / Na再吸収 / ET / NO / メタボリック症候群 / インスリン抵抗性 / グリア細胞 / 細胞内Ca2+シグナル / トリパータイトシナプス / 神経可塑性 / 神経伝達 / 多重リン酸化 / IP3R / multiple phosphorylation / NBCe1変異 / 尿細管性アシドーシス / ラットモデル / 再灌流障害 / 体外灌流モデル / PPARγ / 線維化 / 心機能(収縮能/拡張能) / リポトキシシティ / 活性酸素 / 心機能 / PPARγアゴニスト / 腎障害 / 心血管障害 / 脂質代謝 / アンジオテンシンII / 臨床心血管病態学 / RTA / NBC1(NBCe1) / 細胞容量調節機構 / クロライドチャンネル / 腎毒性物質 Less
  • Research Projects

    (22 results)
  • Research Products

    (185 results)
  • Co-Researchers

    (38 People)
  •  The effect and regulation mechanism of endothelin and nitric oxide specific in human proximal tubule

    • Principal Investigator
      Horita Shoko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Dent病発症の分子メカニズムと腎障害進行機序の解析Principal Investigator

    • Principal Investigator
      関 常司
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Clarifying the role of IRBIT in the coupling regulation of intracellular pH and Ca2+ in astrocytes.

    • Principal Investigator
      MIZUTANI Akihiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Showa Pharmaceutical University
  •  The significance of selective insulin resistance in kidney for hypertension and renal insufficiency.

    • Principal Investigator
      SUZUKI Masashi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  The mechanism of regulation to occur the migraine

    • Principal Investigator
      YAMADA Hideomi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      The University of Tokyo
  •  Effects of PPAR-gamma agonist on lipid contents in the heart and kidney and cardiac function in hypertension/diabetes animal models

    • Principal Investigator
      ISHIZAKA Nobukazu
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka Medical College
  •  Development of new medication against proximal renal tubular acidosisPrincipal Investigator

    • Principal Investigator
      SEKI George
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Functional NBCe1 regulation by proteins'interaction

    • Principal Investigator
      YAMADA Hideomi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Role of cytosolic phospholipase A2 in intrarenalrenin-angiotensin systemPrincipal Investigator

    • Principal Investigator
      SEKI George
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Roles of PPARγ agonists in regulation of body-fluid volume and blood pressurePrincipal Investigator

    • Principal Investigator
      SEKI George
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Prevention of renal cell carcinoma metastasis by selective inhibition of Na-HCO_3 cotransporter

    • Principal Investigator
      MORIYAMA Nobuo
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      FUKUOKA PREFECTURAL UNIVERSITY
  •  Relationship between transport mode and molecular structure in Na-HCO3 cotransporterPrincipal Investigator

    • Principal Investigator
      SEKI George
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  The role of Na-HCO_3 cotransporter in metastasis of renal cell carcinoma

    • Principal Investigator
      MORIYAMA Nobuo
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Fukuoka Prefectural University
      The University of Tokyo
  •  Molecular mechanisms of cataract and glaucoma induced by mutations in the Na-HCO3 cotransporter

    • Principal Investigator
      TANAKA Yoshikazu
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Tokyo Women's Medical University
  •  Phypiology and pathophysiology of Na-HCO3 cotransporterPrincipal Investigator

    • Principal Investigator
      SEKI George
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Roles of orgaric aeid transporter in aeid Seoretion in renal proximal tubules.Principal Investigator

    • Principal Investigator
      SEKI Jyoji
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      University of Tokyo
  •  近位尿細管ATP受容体の生理的意義についての解析Principal Investigator

    • Principal Investigator
      関 常司
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  MOLECULAR MECHANISMS OF ACTION AND PHYSIOLOGICAL ROLES OF LIPID AUTACOIDS IN THE NEPHRON

    • Principal Investigator
      WATANABE Tsuyoshi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      UNIVERSITY OF TOKYO
  •  薬剤性腎障害におけるクロライドチャンネルの役割についての解析

    • Principal Investigator
      鈴木 慶二
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Molecular Cell Biological Analysis on Renal Structure and Function

    • Principal Investigator
      KUROKAWA Kiyoshi
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Kidney internal medicine
    • Research Institution
      University of Tokyo
  •  Analysis of physiological and pathophysiological effects of platelet activating factor on the kidney.

    • Principal Investigator
      TANIGUCHI Shigeo
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      University of Tokyo
  •  Studies on the requlatory mechanisms of renal glomerular and tubular functions.

    • Principal Investigator
      KUROKAWA Kiyoshi
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      内科学一般
    • Research Institution
      Faculty of Medicine, University of Tokyo

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Other

  • [Book] Fluid Management Renaissance 5巻3号 PP.213-219【水電解質代謝異常と遺伝疾患】 尿細管性アシドーシス2015

    • Author(s)
      堀田 晶子, 関 常司
    • Publisher
      (株)メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Book] Role of Renal Sodium Transport in Insulin Resistance and Hypertension; Obesity Epidemic2014

    • Author(s)
      Shoko Horita, Motonobu Nakamura, Masashi Suzuki, Hideomi Yamada and George Seki
    • Publisher
      iConcept Press
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Book] 内科学書 改訂第8版2013

    • Author(s)
      堀田晶子 関常司 山田秀臣
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Book] 改定第8版内科学書2013

    • Author(s)
      堀田 晶子、関 常司、山田 秀臣
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-25461242
  • [Book] 改定第8版内科学書2013

    • Author(s)
      関 常司、堀田 晶子、山田 秀臣
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-25461242
  • [Book] 腎と骨代謝2013

    • Author(s)
      関 常司
    • Publisher
      日本メディカルセンター
    • Data Source
      KAKENHI-PROJECT-25461242
  • [Book] Gene Mutation2012

    • Author(s)
      Seki G, Horita S, Suzuki M, Yamazaki O, Yamada H.
    • Publisher
      Pathophysiological roles ofmutations in the electrogenic Na^+-HCO<3-> cotransporter NBCe1
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Book] 酸塩基平衡を調節するトランスポーター2011

    • Author(s)
      山田秀臣、関常司
    • Publisher
      BIO Clinica
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Book] 腎と透析Vol69増刊号2010

    • Author(s)
      堀田晶子、関常司
    • Total Pages
      4
    • Publisher
      CKDにおいて使われる薬剤-利尿剤-
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Book] 改訂第7版内科学書(近位尿細管機能異常)2009

    • Author(s)
      堀田晶子、関常司、山田秀臣
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Book] 近位尿細管機能異常。改訂第7版内科学書2009

    • Author(s)
      堀田晶子、関常司、山田秀臣
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Book] 近位尿細管性アシドーシスとアンモニア排泄。腎と透析2009

    • Author(s)
      山田秀臣、関常司
    • Publisher
      (東京医学社)
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Book] 腎と透析(Vol 67 近位尿細管性アシドーシスとアンモニア排泄)2009

    • Author(s)
      山田秀臣、関常司
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Book] 改訂第7版内科学書腎尿細管性アシドーシス2009

    • Author(s)
      関常司、堀田晶子、山田秀臣
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Book] Annual Review腎臓NBCl:最近の進歩2009

    • Author(s)
      山田秀臣、関常司
    • Total Pages
      5
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Book] 改訂第7版内科学書(腎尿細管性アシドーシス)2009

    • Author(s)
      関常司、堀田晶子、山田秀臣, その他
    • Total Pages
      520
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Book] 改訂第7版内科学書(腎尿細管性アシドーシス)2009

    • Author(s)
      関常司, 堀田晶子, 山田秀臣
    • Total Pages
      520
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Book] 改訂第7版内科学書(腎尿細管性アシドーシス)2009

    • Author(s)
      関常司、堀田晶子、山田秀臣
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Journal Article] Selective insulin resistance in the kidney2016

    • Author(s)
      Horita S, Nakamura M, Suzuki M, Satoh N, Suzuki A, Seki G.
    • Journal Title

      Biomed Res Int

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Journal Article] Species differences in regulation of renal proximal tubule transport by certain molecules2015

    • Author(s)
      Seki G, Nakamura M, Suzuki M, Satoh S, Horita S
    • Journal Title

      World Journal of Nephrology

      Volume: 4 Issue: 2 Pages: 307-312

    • DOI

      10.5527/wjn.v4.i2.307

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461242, KAKENHI-PROJECT-15K09284, KAKENHI-PROJECT-15K19441
  • [Journal Article] Stimulatory effect of insulin on renal proximal tubule sodium transport is preserved in type 2 diabetes with nephropathy.2015

    • Author(s)
      Motonobu Nakamura; Nobuhiko Satoh; Masashi Suzuki; Haruki Kume; Yukio Homma; George Seki; Shoko Horita
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: in press Issue: 1 Pages: 154-8

    • DOI

      10.1016/j.bbrc.2015.04.005

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461241, KAKENHI-PROJECT-15K09284, KAKENHI-PROJECT-15K19441
  • [Journal Article] Roles of Akt and SGK1 in the Regulation of Renal Tubular Transport.2015

    • Author(s)
      Satoh N, Nakamura M, Suzuki M, Suzuki A, Seki G, Horita S.
    • Journal Title

      Biomed Res Int

      Volume: 2015 Pages: 1-8

    • DOI

      10.1155/2015/971697

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09284, KAKENHI-PROJECT-15K19441, KAKENHI-PROJECT-25461241
  • [Journal Article] Preserved Na/HCO3 cotransporter sensitivity to insulin may promote hypertension in metabolic syndrome.2015

    • Author(s)
      Nakamura M, Yamazaki O, Shirai A, Horita S, Satoh N, Suzuki M, Hamasaki Y, Noiri E, Kume H, Enomoto Y, Homma Y, Seki G
    • Journal Title

      Kidney Int.

      Volume: 87 Issue: 3 Pages: 535-542

    • DOI

      10.1038/ki.2014.351

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591225, KAKENHI-PROJECT-25461241
  • [Journal Article] Thiazolidinediones and Edema: Recent Advances in the Pathogenesis of Thiazolidinediones-Induced Renal Sodium Retention.2015

    • Author(s)
      Horita S, Nakamura M, Satoh N, Suzuki M, Seki G.
    • Journal Title

      PPAR Res

      Volume: 2015 Pages: 1-7

    • DOI

      10.1155/2015/646423

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09284, KAKENHI-PROJECT-15K19441, KAKENHI-PROJECT-25461241
  • [Journal Article] Angiotensin II dose-dependently stimulates human renal proximal tubule transport by the Nitric Oxide/ Guanosine 3', 5'-cyclic monophosphate pathway2014

    • Author(s)
      Shirai A, Yamazaki O, Horita S, Nakamura M, Satoh N, Yamada H, Suzuki M, Kudo A, Kawakami H, Hofmann F, Nishiyama A, Kume H, Enomoto Y, Homma Y, Seki G
    • Journal Title

      J Am Soc Nephrol

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-23390229
  • [Journal Article] Regulatory roles of nitric oxide and angiotensin II on renal tubular transport.2014

    • Author(s)
      Shoko Horita, Motonobu Nakamura, Ayumi Shirai, Osamu Yamazaki, Nobuhiko Satoh, Masashi Suzuki, George Seki
    • Journal Title

      World Journal of Nephrology

      Volume: 3 Issue: 4 Pages: 295-301

    • DOI

      10.5527/wjn.v3.i4.295

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Journal Article] Angiotensin II Dose-Dependently Stimulates Human Renal Proximal Tubule Transport by the Nitric Oxide/Guanosine 3',5'-Cyclic Monophosphate Pathway.2014

    • Author(s)
      Shirai A, Yamazaki O, Horita S, Nakamura M, Satoh N, Yamada H, Suzuki M, Kudo A, Kawakami H, Hofmann F, Nishiyama A, Kume H, Enomoto Y, Homma Y, Seki G.
    • Journal Title

      J Am Soc Nephrol.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390229
  • [Journal Article] Roles of renal proximal tubule transport in the pathogenesis of hypertension.2013

    • Author(s)
      Horita S, Seki G, Yamada H, Suzuki M, Koike K, Fujita T.
    • Journal Title

      Curr Hypertens Rev.

      Volume: 9 Pages: 148-55

    • Data Source
      KAKENHI-PROJECT-23390229
  • [Journal Article] Mutation of the Mg^(2+) Transporter SLC41A1 Results in a Nephronophthisis-Like Phenotype.2013

    • Author(s)
      Hurd TW, Otto EA, Mishima E, Gee HY, Inoue H, Inazu M, Yamada H, Halbritter J, Seki G, Konishi M, Zhou W, Yamane T, Murakami S, Caridi G, Ghiggeri G, Abe T, Hildebrandt F
    • Journal Title

      J Am Soc Nephrol.

      Volume: 24 Issue: 6 Pages: 967-977

    • DOI

      10.1681/asn.2012101034

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590248, KAKENHI-PROJECT-23390033, KAKENHI-PROJECT-23390229, KAKENHI-PROJECT-24659062
  • [Journal Article] Irbit Mediates Synergy Between Ca2+ and cAMP Signaling Pathways During Epithelial Transport in Mice.2013

    • Author(s)
      Park S, Shcheynikov N, Hong JH, Zheng C, Suh SH, Kawaai K, Ando H, Mizutani A, Abe T, Kiyonari H, Seki G, Yule D, Mikoshiba K, Muallem S
    • Journal Title

      Gastroenterology

      Volume: S0016-5085(13) Issue: 1 Pages: 232-241

    • DOI

      10.1053/j.gastro.2013.03.047

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500458, KAKENHI-PROJECT-24590332, KAKENHI-PROJECT-24591225, KAKENHI-PROJECT-24700389, KAKENHI-PROJECT-25221002
  • [Journal Article] 尿細管性アシドーシスの分類とその機序2013

    • Author(s)
      山田秀臣, 関常司
    • Journal Title

      Nephrology Frontier

    • Data Source
      KAKENHI-PROJECT-23390229
  • [Journal Article] Mutation of the renal Mg2+ transporter SLC41A1 in a nephronophthisis-like phenotype.2013

    • Author(s)
      Hurd TW, Edgar Otto EA, Mishima E, Gee HY, Hana Inoue4, Inazu M, Yamada H, Halbritter J, Seki G, Konishi M, Zhou W, Yamane T, Murakami S, Caridi G, Ghiggeri G, Abe T, Hildeb F.
    • Journal Title

      J Am Soc Nephrol

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591225
  • [Journal Article] The acid-base regulation by renal proximal tubule.2013

    • Author(s)
      Horita S, Nakamura M, Yamada H, Suzuki M, Seki G.
    • Journal Title

      Open Journal of Molecular and Integrative Physiology

      Volume: 3 Issue: 04 Pages: 186-193

    • DOI

      10.4236/ojmip.2013.34024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461242
  • [Journal Article] Unexpected effect of an appetite-stimulating hormone ghrelin on ENaC: hunger for sodium?2013

    • Author(s)
      Seki G
    • Journal Title

      Kidney Int

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591225
  • [Journal Article] Roles of renal proximal tubule transport in the pathogenesis of hypertension.2013

    • Author(s)
      Horita S, Seki G, Yamada H, Suzuki M, Koike K, Fujita T.
    • Journal Title

      Curr Hypertens Rev

      Volume: 9 Issue: 2 Pages: 148-55

    • DOI

      10.2174/15734021113099990009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591225, KAKENHI-PROJECT-25461241
  • [Journal Article] Molecular mechanisms of renal and extrarenal manifestations caused by inactivation of the electrogenic Na(+)-HCO(3)(-) cotransporter NBCe1.2013

    • Author(s)
      Seki G, Horita S, Suzuki M, Yamazaki O, Usui T, Nakamura M, Yamada H.
    • Journal Title

      Front Physiol.

      Volume: 4 Pages: 270-270

    • Data Source
      KAKENHI-PROJECT-23390229
  • [Journal Article] Pathophysiological roles of mutations in the electrogenic Na+-HCO3- cotransporter NBCe12012

    • Author(s)
      Seki G, Horita S, Suzuki M, Yamazaki O, Yamada H
    • Journal Title

      Mutations in Human Genetic Disease

      Volume: 167-180

    • Data Source
      KAKENHI-PROJECT-23390229
  • [Journal Article] Functional Roles of Electrogenic Sodium Bicarbonate Cotransporter NBCe1 in Ocular Tissues.2012

    • Author(s)
      Suzuki M, Seki G, Yamada H, Horita S, Fujita T.
    • Journal Title

      Open Ophthalmol J.

      Volume: 6 Issue: 1 Pages: 36-41

    • DOI

      10.2174/1874364101206010036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790932, KAKENHI-PROJECT-24591225
  • [Journal Article] 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor simvastatin ameliorates renal fibrosis through HOXA13-USAG-1 pathway.2012

    • Author(s)
      Hamasaki Y, et al.
    • Journal Title

      Laboratory Investigation

      Volume: 92 Issue: 8 Pages: 1161-70

    • DOI

      10.1038/labinvest.2012.71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390212, KAKENHI-PROJECT-24591225
  • [Journal Article] Role of renal proximal tubule transport in thiazolidinediones -induced volume expansion2012

    • Author(s)
      Seki G, Endo Y, Suzuki M, Yamada H, Horita S, Fujita T
    • Journal Title

      World Journal of Nephrology 6

      Volume: 1(5) Pages: 146-150

    • Data Source
      KAKENHI-PROJECT-23390229
  • [Journal Article] Re-lowering of serum Na for osmotic demyelinating syndrome.2012

    • Author(s)
      Yamada H, Takano K, Ayuzawa N, Seki G and Fujita T.
    • Journal Title

      Case Reports in Neurological Medicine

      Volume: 2012 Pages: 704639-704639

    • DOI

      10.1155/2012/704639

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591348, KAKENHI-PROJECT-24591225
  • [Journal Article] The long-term use of enalapril and hydrochlorothiazide in two novel mutations patients with Dent's disease type 12012

    • Author(s)
      Vaisbich MH, Henriques Ldos S, Igarashi T, Sekine T, Seki G, Koch VH
    • Journal Title

      J Bras Nefrol

      Volume: 34(1) Pages: 78-81

    • Data Source
      KAKENHI-PROJECT-21591051
  • [Journal Article] Functional roles of electrogenic sodium bicarbonate cotransporter NBCe1 in ocular tissues2012

    • Author(s)
      Suzuki M, Seki G, Yamada H, Horita S, Fujita T
    • Journal Title

      The Open Ophthalmology Journal 6

      Pages: 36-41

    • Data Source
      KAKENHI-PROJECT-23390229
  • [Journal Article] Thiazolidinediones enhance sodium-coupled bicarbonate absorption from renal proximal tubules via PPAR・-dependent non-genomic signaling2011

    • Author(s)
      Endo Y, Suzuki M, Yamada H, Horita S, Kunimi M, Yamazaki O, Shirai A, Nakamura M, Iso-O N, Li Y, Hara M, Tsukamoto K, Moriyama N, Kudo A, Kawakami H, Yamauchi T, Kubota N, Kadowaki T, Kume H, Enomoto Y, Homma Y, Seki G, Fujita T
    • Journal Title

      Cell Metab

      Volume: 13 Pages: 550-561

    • Data Source
      KAKENHI-PROJECT-23390229
  • [Journal Article] Lin S : Physiological and pathophysiological roles of the electrogenic Na^+-HCO_<3-> cotransporter NBCe12011

    • Author(s)
      Seki G, Yamada H, Horita S, Suzuki M, Yamazaki O, Van Paesschen W, Yang S
    • Journal Title

      Open Journal of Molecular and Integrative Physiology

      Volume: 1 Pages: 9-16

    • Data Source
      KAKENHI-PROJECT-21591051
  • [Journal Article] Physiological and pathophysiological roles of the electrogenic Na+-HCO3- cotransporter NBCe12011

    • Author(s)
      Seki G, Yamada H, Horita S, Suzuki M, Yamazaki O, Van Paesschen W, Yang S, Lin S
    • Journal Title

      Open Journal of Molecular and Integrative Physiology

      Volume: 1 Pages: 9-16

    • Data Source
      KAKENHI-PROJECT-23390229
  • [Journal Article] Functional characterization of nonsynonymous single nucleotide polymorphisms in the electrogenic Na^+-HCO_<3-> cotransporter NBCe1A2011

    • Author(s)
      Yamazaki O, Yamada H, Suzuki M, Horita S, Shirai A, Nakamura M, SekiG, Fujita T
    • Journal Title

      Pflugers Arch

      Volume: 461 Pages: 249-259

    • Data Source
      KAKENHI-PROJECT-21591051
  • [Journal Article] Severe Metabolic Acidosis Causes Early Lethality in NBC1 W516X Knock-in Mice as a Model of Human Isolated Proximal Renal Tubular Acidosis2011

    • Author(s)
      Lo Y, BS, Yang S, Seki G, Yamada H, Horita S, Yamazaki O, Fujita T, MD, Usui T, Tsai J, Yu I, PhD6, Lin S, Lin S
    • Journal Title

      Kidney Int

      Volume: 79 Pages: 730-741

    • Data Source
      KAKENHI-PROJECT-23390229
  • [Journal Article] Functional characterization of non-synonymous single nucleotide polymorphisms in the electrogenic Na^+-HCO_3^- cotransporter NBCe1A.2011

    • Author(s)
      Yamazaki O, Yamada H, Suzuki M, Horita S, Shirai A, Nakamura M, Seki G, Fujita T
    • Journal Title

      Pflugers Arch 461

      Pages: 249-259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Journal Article] Severe Metabolic Acidosis Causes Early Lethality in NBC1 W516X Knock-in Mice as a Model of Human Isolated Proximal Renal Tubular Acidosis2011

    • Author(s)
      Lo Y, BS, Yang S, Seki G, Yamada H, Horita S, Yamazaki O, Fujita T, MD, Usui T, Tsai J, Yu I, PhD, Lin S, Lin S
    • Journal Title

      Kidney Int

      Volume: 79 Pages: 730-741

    • Data Source
      KAKENHI-PROJECT-21591051
  • [Journal Article] Severe Metabolic Acidosis Causes Early Lethality in NBC1 W516X Knock-in Mice as a Model of Human Isolated Proximal Renal Tubular Acidosis.2011

    • Author(s)
      Lo Y, BS, Yang S, Seki G, Yamada H, Horita S, et al.
    • Journal Title

      Kidney Int

      Volume: 79 Pages: 730-741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Journal Article] Severe Metabolic Acidosis Causes Early Lethality in NBC1 W516X Knock-in Mice as a Model of Human Isolated Proximal Renal Tubular Acidosis.2011

    • Author(s)
      Lo Y, BS, Yang S, Seki G, Yamada H, Horita S, Yamazaki O, Fujita T, MD, Usui T, Tsai J, Yu I, PhD6, Lin S, Lin S
    • Journal Title

      Kidney Int 9

      Pages: 730-741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Journal Article] IRBIT governs murine epithelial secretion by antagonizing the function of the WNK/SPAK kinases pathway2011

    • Author(s)
      YongD, Li Q, So I, Huang CL, Ando H, Mizutani A, Seki G, Mikoshiba K, Thomas PJ, Muallem S
    • Journal Title

      J ClinInvest

      Volume: 121 Pages: 956-965

    • Data Source
      KAKENHI-PROJECT-21591051
  • [Journal Article] Functional role of a putative carbonic anhydrase II-binding domain in the electrogenic Na^+-HCO_3^- cotransporter NBCe1 expressed in Xenopus oocytes2011

    • Author(s)
      Yamada H, Horita S, Suzuki M, Fujita F, Seki G
    • Journal Title

      Channels

      Volume: 5 Issue: 2 Pages: 1-4

    • DOI

      10.4161/chan.5.2.14341

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591051, KAKENHI-PROJECT-23390229
  • [Journal Article] Functional characterization of non -synonymous single nucleotide poly -morphisms in the electrogenic Na+-HCO3- cotransporter NBCe1A2011

    • Author(s)
      Yamazaki O, Yamada H, Suzuki M, Horita S, Shirai A, Nakamura M, Seki G, Fujita T
    • Journal Title

      Pflugers Arch

      Volume: 461 Pages: 249-259

    • Data Source
      KAKENHI-PROJECT-23390229
  • [Journal Article] Functional role of a putative carbonic anhydrase II-binding domain in the electrogenic Na^+-HCO_3^- cotransporter NBCe1 expressed in Xenopus oocytes.2011

    • Author(s)
      Yamada H, Horita S, Suzuki M, Fujita F, Seki G
    • Journal Title

      Channels 5:2

      Pages: 1-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Journal Article] Functional role of a putative carbonic anhydrase II-binding domain in the electrogenic Na+-HCO3- cotransporter NBCe1 expressed in Xenopus oocytes2011

    • Author(s)
      Yamada H, Horita S, Suzuki M, Fujita F, Seki G
    • Journal Title

      Channels

      Volume: 5:2 Pages: 1-4

    • Data Source
      KAKENHI-PROJECT-23390229
  • [Journal Article] 酸塩基平衡を調節するトランスポーター2011

    • Author(s)
      山田秀臣, 関常司
    • Journal Title

      BIO Clinica

      Volume: Vol26 No11 Pages: 34-40

    • Data Source
      KAKENHI-PROJECT-23390229
  • [Journal Article] IRBIT governs murine epithelial secretion by antagonizing the function of the WNK/SPAK kinases pathway.2011

    • Author(s)
      YongD, Li Q, Huang CL, Ando H, Mizutani A, Seki G, et al
    • Journal Title

      J Clin Invest

      Volume: 121 Pages: 956-965

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Journal Article] Thiazolidinediones enhance sodium-coupled bicarbonate absorption from renal proximal tubules via PPARγ-dependent non-genomic signaling2011

    • Author(s)
      Endo Y, Suzuki M, Yamada H, Horita S, Kunimi M, Yamazaki O, Shirai A, Nakamura M, Iso-O N, Li Y, Hara M, Tsukamoto K, Moriyama N, Kudo A, Kawakami H, Yamauchi T, Kubota N, Kadowaki T, Kume H, Enomoto Y, Homma Y, Seki G, Fujita T
    • Journal Title

      Cell Metab

      Volume: 13 Pages: 550-561

    • Data Source
      KAKENHI-PROJECT-21591051
  • [Journal Article] Functional role of a putative carbonic anhydrase II-binding domain in the electrogenic Na^+-HCO_<3-> cotransporter NBCe1 expressed in Xenopus oocytes2011

    • Author(s)
      Yamada H, Horita S, Suzuki M, FujitaF, Seki G
    • Journal Title

      Channels

      Volume: 5 : 2 Pages: 1-4

    • Data Source
      KAKENHI-PROJECT-21591051
  • [Journal Article] Insulin resistance, obesity, hypertension and renal sodium transport2011

    • Author(s)
      Horita S, Seki G, Yamada H, Suzuki M, Koike K, Fujita T
    • Journal Title

      Int J Hypertension

      Volume: 2011 Pages: 391762-391762

    • DOI

      10.4061/2011/391762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591051, KAKENHI-PROJECT-23390229, KAKENHI-PROJECT-23790932
  • [Journal Article] Metabolic syndrome and insulin signaling in kidney2011

    • Author(s)
      Horita S, Seki G, Yamada H, Suzuki M, Nakamura M, Fujita T.
    • Journal Title

      Endocrinol Metabol Syndrome

      Volume: S1 : 005 Issue: S1 Pages: 5-5

    • DOI

      10.4172/2161-1017.s1-005

    • Data Source
      KAKENHI-PROJECT-21591051, KAKENHI-PROJECT-23390229
  • [Journal Article] Defective membrane expression of the Na+-HCO3-cotransporter NBCe1 is associated with familial migraine.2010

    • Author(s)
      Suzuki M, Stalmans I, Horita S, Yamada H, Seki G, et al
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 107 Pages: 15963-15968

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Journal Article] Human sodium-phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate.2010

    • Author(s)
      Jutabha P, Anzai N, Kitamura K, Taniguchi A, Kaneko S, Yan K, Yamada H, Shimada H, Kimura T, Katada T, Fukutomi T, Tomita K, Urano W, Yamanaka H, Seki G, Fujita T, Moriyama Y, Yamada A, Uchida S, Michael F.Wempe MF, Endou H, Sakurai H
    • Journal Title

      J Biol Chem 285

      Pages: 35123-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Journal Article] Defective membrane expression of the Na^+-HCO_3^- cotransporter NBCe1 is associated with familial migraine.2010

    • Author(s)
      Suzuki M, Paesschen WV, Stalmans I, Horita S, Yamada H, Bergmans BA, Legius E, Riant F, Jonghe PD, Li Y, Sekine T, Igarashi T, Fujimoto I, Mikoshiba M, Shimadzu M, Shiohara M, Braverman N, Al-Gazali L, Fujita Y, Seki G
    • Journal Title

      Proc Natl Acad Sci U S A 107

      Pages: 15963-15968

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Journal Article] Defective membrane expression of the Na^+-HCO<3-> cotransporter NBCe1 is associated with familial migraine2010

    • Author(s)
      Suzuki M, Paesschen WV, Stalmans I, Horita S, Yamada H, Bergmans BA, Legius E, Riant F, Jonghe PD, Li Y, Sekine T, Igarashi T, Fujimoto I, KMikoshiba M, Shimadzu M, Shiohara M, Braverman N, Al-Gazali L, Fujita Y, Seki G
    • Journal Title

      Proc Natl AcadSci USA

      Volume: 107 Pages: 15963-15968

    • Data Source
      KAKENHI-PROJECT-21591051
  • [Journal Article] Roles of MEK/ERK pathway in vascular and renal tubular actions of angiotensin II.2009

    • Author(s)
      Seki G, Yamada H, Li Y, Horita S, Ishizaka N, Koike K, Fujita T
    • Journal Title

      Vascular Disease Prevention 6

      Pages: 154-159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Journal Article] 近位尿細管性アシドーシスとアンモニア排泄2009

    • Author(s)
      山田秀臣, 関常司
    • Journal Title

      腎と透析 67

      Pages: 53-55

    • Data Source
      KAKENHI-PROJECT-20590971
  • [Journal Article] Roles ofMEK/ERK pathway in vascular and renaltubular actions of angiotensin II2009

    • Author(s)
      Seki G, Yamada H, Li Y, Horita S, Ishizaka N, Koike K and Fujita T
    • Journal Title

      Vascular Disease Prevention 6

      Pages: 154-159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Journal Article] Roles of MEK/ERK pathway in vascular and renal tubular actions of angiotensin II2009

    • Author(s)
      Seki G, Yamada H, Li Y, Horita S, Ishizaka N, Koike K, Fujita T
    • Journal Title

      Vascular Disease Prevention 6

      Pages: 154-159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Journal Article] Roles of MEK/ERK pathway in vascular and renal tubular actions of angiotensin II.2009

    • Author(s)
      Seki G, Yamada H, Li Y, Horita S, Ishizaka N, Koike K, Fujita T
    • Journal Title

      Vascular Disease Prevention 6

      Pages: 154-159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Journal Article] Roles of MEK/ERK pathway in vascular and renal tubular actions of angiotensin II2009

    • Author(s)
      Seki G, Yamada H, Li Y, Horita S, Ishizaka N, Koike K and Fujita T
    • Journal Title

      Vascular Disease Prevention

      Volume: 6 Pages: 154-159

    • Data Source
      KAKENHI-PROJECT-21591051
  • [Journal Article] 近位尿細管性アシドーシスとアンモニア排泄2009

    • Author(s)
      山田秀臣、関常司
    • Journal Title

      腎と透析 67

      Pages: 53-55

    • Data Source
      KAKENHI-PROJECT-21591051
  • [Journal Article] Functionalanalysis of a novel missense NBC1mutation and of other mutations causingproximal renal tubular acidosis2008

    • Author(s)
      Suzuki M, Vaisbich M, Yamada H,Horita S, Li Y, Sekine T, Moriyama N,Igarashi T, Endo Y, Cardoso T, de Sa L,Koch H, Seki G, Fujita, T
    • Journal Title

      Pflugers Arch 455

      Pages: 583-593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Journal Article] The Roles of Abnormal Renal Sodium Handling in Hypertension Associated with Metabolic Syndrome.2008

    • Author(s)
      Seki G, Yamada H, Li Y, Horita S, Suzuki M, Fujita T
    • Journal Title

      Current Hypertension Reviews 4

      Pages: 197-202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Journal Article] Association of CigaretteSmoking with Chronic Kidney Disease in Japanese men2008

    • Author(s)
      Ishizaka N, Ishizaka Y, Toda E,Shimomura H, Koike K, Seki G, Nagai R, Yamakado M
    • Journal Title

      Hypertension Res 31

      Pages: 485-492

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Journal Article] The Roles ofAbnormal Renal Sodium Handling inHypertension Associated with MetabolicSyndrome2008

    • Author(s)
      Seki G, Yamada H, Li Y, Horita S, Suzuki M and Fujita T
    • Journal Title

      Current Hypertension Reviews 4

      Pages: 197-202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Journal Article] Arachidonic acid metabolites inhibit the stimulatory effect of angiotensin II in renal proximal tubules.2008

    • Author(s)
      Li Y, Yamada H, Kita Y, Suzuki M, Endo Y, Horita S, Yamazaki O, Shimizu T, Seki G, Fujita T
    • Journal Title

      Hypertension Res 31

      Pages: 2155-2164

    • NAID

      10024828609

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Journal Article] Activation and Inactivation Mechanisms of Na-HCO3 Cotransporter NBC12008

    • Author(s)
      Seki G, Yamada H, Horita S, Suzuki M, Sekine T, Igarashi T and Fujita T
    • Journal Title

      J Epithelial Biology and Pharmacology 1

      Pages: 35-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Journal Article] Functional analysis of a novel missense NBC1 mutation and of other mutations causing proximal renal tubular acidosis.2008

    • Author(s)
      Suzuki M, Vaisbich M, Yamada H, Horita S, Li Y, Sekine T, Moriyama N, Igarashi T, Endo Y, Cardoso T, de Sa L, Koch H, Seki G, Fujita, T
    • Journal Title

      Pflugers Arch 455

      Pages: 583-593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Journal Article] Activation and Inactivation Mechanisms of Na-HCO3 Cotransporter NBC1.2008

    • Author(s)
      Seki G, Yamada H, Horita S, Suzuki M, Sekine T, Igarashi T, Fujita T
    • Journal Title

      J Epithelial Biology and Pharmacology 1

      Pages: 35-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Journal Article] Roles of ERK and cPLA2in the angiotensin II-mediated biphasicregulation of Na + - HCO3 - transport2008

    • Author(s)
      Li Y, Yamada H, Kita Y, Kunimi M, Horita S, Suzuki M, Endo Y, Shimizu T,Seki G, Fujita T
    • Journal Title

      J Am Soc Nephrol 19

      Pages: 252-259

    • Data Source
      KAKENHI-PROJECT-19590934
  • [Journal Article] The Roles of Abnormal Renal Sodium Handling in Hypertension Associated with Metabolic Syndrome2008

    • Author(s)
      Seki G et al.
    • Journal Title

      Current Hypertension Reviews 4

      Pages: 197-202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Journal Article] Arachidonic acid metabolitesinhibit the stimulatory effect of angiotensin II in renal proximal tubules2008

    • Author(s)
      Li Y, Yamada H, Kita Y, Suzuki M, EndoY, Horita S, Yamazaki O, Shimizu T, SekiG, Fujita T
    • Journal Title

      Hypertension Res 31

      Pages: 2155-2164

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Journal Article] Roles of ERK and cPLA2 in the angiotensin II-mediated biphasic regulation of Na^+-HCO_3^- transport.2008

    • Author(s)
      Li Y, Yamada H, Kita Y, Kunimi M, Horita S, Suzuki M, Endo Y, Shimizu T, Seki G, Fujita T
    • Journal Title

      J Am Soc Nephrol 19

      Pages: 252-259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Journal Article] Activation and Inactivation Mechanisms of Na-HCO3 Cotransporter NBCl2008

    • Author(s)
      Seki G et al.
    • Journal Title

      J Epithelial Biology and Pharmacology 1

      Pages: 35-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Journal Article] Interaction ofmembrane skeletal protein, protein 4.1Band p55 and sodium-bicarbonatecotransporter1 in mouse renal S1-S2proximal tubules2007

    • Author(s)
      Terada N, Ohno N, Saitoh S, Seki G, Komada M, Suzuki T, Yamakawa H, Soleimani M, Ohno S
    • Journal Title

      J Histochem Cytochem 55

      Pages: 1199-1206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Journal Article] Associationbetween Obesity and Chronic KidneyDisease in Japanese : Differences in Genderand Hypertensive Status?2007

    • Author(s)
      Ishizaka N, Ishizaka Y, Koike K, Seki G, Nagai R, Yamakado M
    • Journal Title

      Hypertension Res 30

      Pages: 1059-1064

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Journal Article] Association between Chronic KidneyDisease and Carotid Intima-MediaThickening in Individuals withHypertension and Impaired GlucoseMetabolism2007

    • Author(s)
      Ishizaka N, Ishizaka Y, Toda E, KoikeK, Seki G, Nagai R, Yamakado M
    • Journal Title

      Hypertension Res 30

      Pages: 1035-1041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Journal Article] Localization of NBC1 variants in rat kidney.2006

    • Author(s)
      Endo Y, Yamazaki S, Moriiyama N, Li Y, Ariizumi T, Seki G et al.
    • Journal Title

      Nephron (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590779
  • [Journal Article] An alcoholic with recurrent renal failure and proteinuria2006

    • Author(s)
      Kumagai T, Hod Y, Seki G, Fujita T
    • Journal Title

      Kidney Int (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590779
  • [Journal Article] Localization of NBC1 variants in rat kidney.2006

    • Author(s)
      Endo Y, Yamazaki S, Moriyama N, Li Y, Ariizumi T, Kudo A, Kawakami H, Tanaka Y, Horita S, Yamada H, Seki G, Fujita T
    • Journal Title

      Nephron 103(in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591614
  • [Journal Article] An alcoholic with recurrent renal failure and proteinuria2006

    • Author(s)
      Kumagai T, Hori Y, Seki G, Fujita T
    • Journal Title

      Kidney Int (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590779
  • [Journal Article] Functional analysis of NBC1 mutants associated with proximal renal tubular acidosis and ocular abnormalities.2005

    • Author(s)
      Horita S, Yamada H, Inatomi J, Moriyama N, Sekine T, Igarashi T, Endo Y, Dasouki M, Ekim M, Al-Gazali L, Shimadzu M, Seki G, Fujita T
    • Journal Title

      J Am Soc Nephrol 16

      Pages: 2270-2278

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591614
  • [Journal Article] Roles of insulin receptor substrates in insulin-induced stimulation of renal proximal bicarbonate absorption.2005

    • Author(s)
      Zheng Y, Yamada H, Sakamoto K, Horita S, Seki G et al.
    • Journal Title

      J Am Soc Nephrol 16

      Pages: 2288-2295

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590779
  • [Journal Article] Functional analysis of NBC1 mutants associated with proximal renal tubular acidosis and ocular abnormalities.2005

    • Author(s)
      Horita S, Yamada H, Inatomi J, Moriyama N, Seki G et al.
    • Journal Title

      J Am Soc Nephrol 16

      Pages: 2270-2278

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590779
  • [Journal Article] Functional analysis of NBC1 mutants associated with proximal renal tubular acidosis and ocular abnormalities2005

    • Author(s)
      Horita S, Yamada H, Moriyama N, Seki G, Igarashi T, Fujita T, et al.
    • Journal Title

      J Am Soc Nephrol (In press)

    • Data Source
      KAKENHI-PROJECT-16591614
  • [Journal Article] Functional analysis of NBC1 mutants associated with proximal renal tubular acidosis and ocular abnormalities2005

    • Author(s)
      Horita S, Yamada H, Moriyama N, Seki G, Igarashi T, Fujita T et al.
    • Journal Title

      J Am Soc Nephrol (In press)

    • Data Source
      KAKENHI-PROJECT-16590779
  • [Journal Article] Immunoelectron microscopic localization of protein 4.1B in proximal S1 and S2 tubules of rodent kidneys2004

    • Author(s)
      Terada N, Ohono N, Fujii Y, Baba T, Seki G et al.
    • Journal Title

      Med Electron Microsc 37

      Pages: 45-51

    • Data Source
      KAKENHI-PROJECT-16590779
  • [Journal Article] Mutational and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis.2004

    • Author(s)
      Inatomi J, Igarashi T, Moriyama N, Seki G, Fujita T et al.
    • Journal Title

      Pflugers Arch 448

      Pages: 438-444

    • Data Source
      KAKENHI-PROJECT-16590779
  • [Journal Article] Mutational and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis.2004

    • Author(s)
      Inatomi J, Igarashi T, Moriyama N, Seki G, Fujita T et al.
    • Journal Title

      Pflugers Arch 448

      Pages: 438-444

    • Data Source
      KAKENHI-PROJECT-16591614
  • [Presentation] インスリンによる近位尿細管Na再吸収亢進作用はAkt2とmTORC2を介している2016

    • Author(s)
      中村元信,鈴木正志,佐藤信彦,鈴木淳司,関常司,久米春喜,本間之夫,堀田晶子,南学正臣
    • Organizer
      第59回日本腎臓学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-06-18
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] 近位尿細管管腔側Na依存性酸塩基輸送機構の種差2016

    • Author(s)
      鈴木淳司,鈴木正志,中村元信,佐藤信彦,関常司,久米春喜,本間之夫,堀田晶子,南学正臣
    • Organizer
      第59回日本腎臓学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] インスリンの近位尿細管Na輸送亢進作用は進行した糖尿病性腎症の高血圧維持に重要である2015

    • Author(s)
      中村 元信, 堀田 晶子, 鈴木 正志, 佐藤 信彦, 本間 之夫, 久米 春喜, 関 常司
    • Organizer
      第58回日本腎臓学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-06-06
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] V-ATPase in Luminal Membrane of Renal Proximal Tubule Requires B2 Subunit and CLC-5 for Its Full Functional Activity2015

    • Author(s)
      Sato N, Nakamura M, Suzuki A, Suzuki M, Seki G, Horita S.
    • Organizer
      American Society of Nephrology Kidney Week 2015
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-11-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] 微小灌流法を用いない単離近位尿細管管腔側輸送体機能の新規解析法2015

    • Author(s)
      佐藤 信彦, 堀田 晶子, 中村 元信, 鈴木 正志, 本間 之夫, 久米 春喜, 関 常司
    • Organizer
      第58回日本腎臓学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-06-06
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] 微小灌流法を用いない単離近位尿細管管腔側輸送体機能の新規解析法2015

    • Author(s)
      佐藤 信彦, 中村 元信, 鈴木 正志, 堀田 晶子, 関 常司
    • Organizer
      第58回日本腎臓学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2015-06-06
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] Insulin Stimulates Renal Proximal Tubule Sodium Transport in Overt Type 2 Diabetic Nephropathy2015

    • Author(s)
      Nakamura M, Sato N, Suzuki M, Suzuki A, Kume H, Homma Y, Seki G, Horita S.
    • Organizer
      American Society of Nephrology Kidney Week 2015
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-11-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] インスリンはPI3キナーゼ/IRS2/Akt2を介して近位尿細管Na再吸収を亢進させる2014

    • Author(s)
      中村 元信, 白井 雅弓, 山田 秀臣, 堀田 晶子, 鈴木 正志, 佐藤 信彦, 濱崎 敬文, 野入 英世, 関 常司
    • Organizer
      第57回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-07-06
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] インスリンはPI3キナーゼ/IRS2/Akt2を介して近位尿細管Na再吸収を亢進させる2014

    • Author(s)
      中村 元信、白井 雅弓、山田 秀臣、堀田 晶子、鈴木 正志、佐藤 信彦、濱崎 敬文、野入 英世、関 常司
    • Organizer
      第57回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-07-06
    • Data Source
      KAKENHI-PROJECT-24591225
  • [Presentation] インスリン抵抗性における腎近位尿細管インスリンシグナル伝達保持機構2014

    • Author(s)
      中村 元信, 白井 雅弓, 山田 秀臣, 堀田 晶子, 鈴木 正志, 佐藤 信彦, 本間 之夫, 久米 春喜, 関 常司
    • Organizer
      第57回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-07-06
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] CLC5の2Cl/H交換輸送はH-ATPase最大活性化に必要である2014

    • Author(s)
      佐藤 信彦、山田 秀臣、山崎 修、堀田 晶子、鈴木 正志、芦田 明、山本 大助、郭 義胤、関根 孝司、関 常司
    • Organizer
      日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-07-06
    • Data Source
      KAKENHI-PROJECT-25461242
  • [Presentation] 2Cl/H exchange function of CLC-5 is required for the H-ATPase-mediated maximal endosome acidification2014

    • Author(s)
      Nobuhiko Sato, Hideomi Yamada, Osamu Yamazaki, Shoko Horita, Masashi Suzuki, Motonobu Nakamura, Yoshitsugu Kaku, Daisuke Yamamoto, Akira Ashida, Takashi Sekine, George Sek
    • Organizer
      ASN Annual Meeting
    • Place of Presentation
      フィラデルフィア
    • Year and Date
      2014-11-14
    • Data Source
      KAKENHI-PROJECT-25461242
  • [Presentation] CLC5の2Cl/H交換輸送はH-ATPase最大活性化に必要である2014

    • Author(s)
      佐藤 信彦, 山田 秀臣, 山崎 修, 堀田 晶子, 鈴木 正志, 芦田 明, 山本 大助, 関根 孝司, 郭 義胤, 関 常司
    • Organizer
      第57回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-07-06
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] インスリン抵抗性における腎近位尿細管インスリンシグナル伝達保持機構2014

    • Author(s)
      中村 元信、白井 雅弓、山田 秀臣、堀田 晶子、鈴木 正志、佐藤 信彦、本間 之夫、久米 春喜、関 常司
    • Organizer
      第57回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-07-06
    • Data Source
      KAKENHI-PROJECT-24591225
  • [Presentation] インスリン抵抗性におけるインスリンの近位尿細管作用機序2013

    • Author(s)
      中村元信、山崎修、白井雅弓、山田秀臣、堀田晶子、鈴木正志、榎本裕、久米春喜、本間之夫、関常司
    • Organizer
      第56回日本腎臓学会学術総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24591225
  • [Presentation] インスリン抵抗性におけるインスリンの近位尿細管作用機序2013

    • Author(s)
      中村 元信, 山崎 修, 白井 雅弓, 山田 秀臣, 堀田 晶子, 鈴木 正志, 榎本 裕, 久米 春喜, 本間 之夫, 関 常司
    • Organizer
      第56回日本腎臓学会学術総会
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] Loss of 2Cl/H exchange function of CLC-5 causes Dent’s disease2013

    • Author(s)
      Nobuhiko Sato, Hideomi Yamada, Osamu Yamazaki, Shoko Horita, Masashi Suzuki, Motonobu Nakamura, Yoshitsugu Kaku, Daisuke Yamamoto, Akira Ashida, Takashi Sekine, George Seki
    • Organizer
      Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-25461242
  • [Presentation] CLC5の2Cl/H交換輸送機能の喪失はDent病を生じる2013

    • Author(s)
      佐藤 信彦, 山田 秀臣, 山崎 修, 堀田 晶子, 鈴木 正志, 芦田 明, 山本 大助, 郭 義胤, 関根 孝司, 関 常司
    • Organizer
      第56回日本腎臓学会学術総会
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] Loss of 2Cl/H Exchange Function of CLC-5 Causes Dent’s Disease2013

    • Author(s)
      Nobuhiko Sato, Hideomi Yamada, Osamu Yamazaki, Shoko Horita, Masashi Suzuki, Motonobu Nakamura, Yoshitsugu Kaku, Daisuke Yamamoto, Akira Ashida, Takashi Sekine, George Seki.
    • Organizer
      Kidney Week 2013
    • Place of Presentation
      Atlanta, U.S.A.
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] CLC5の2Cl/H交換輸送機能の喪失はDent病を生じる2013

    • Author(s)
      佐藤 信彦、山田 秀臣、山崎 修、堀田 晶子、鈴木 正志、芦田 明、山本 大助、郭 義胤、関根 孝司、関 常司
    • Organizer
      第56回日本腎臓学会学術総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25461242
  • [Presentation] NO/sGC/cGMP/ERK pathway mediates a unique dose-dependent stimulation of human proximal transport by angiotensin II.2012

    • Author(s)
      Ayumi Shirai, Osamu Yamazaki, Motonobu Nakamura, Hideomi Yamada, Masashi Suzuki, Shoko Horita, Yukio Homma, George Seki
    • Organizer
      Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-24591225
  • [Presentation] IRBITのpNBCへの結合と活性には、IRBITのcasein kinase IIによるリン酸化が必須である。2012

    • Author(s)
      水谷顕洋、山田秀臣、山崎脩、関常司、御子柴克彦
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場・マリンメッセ福岡(福岡市)
    • Data Source
      KAKENHI-PROJECT-24590332
  • [Presentation] インスリン抵抗性におけるインスリンの近位尿細管輸送亢進作用機序2012

    • Author(s)
      中村元信, 山崎修, 白井雅弓, 山田秀臣, 堀田晶子, 鈴木正志, 榎本裕, 久米春喜, 本間之夫, 関常司, 藤田敏郎
    • Organizer
      第55回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2012-06-02
    • Data Source
      KAKENHI-PROJECT-23390229
  • [Presentation] Stimulatory effect of insulin on renal proximal Na transport is preserved in insulin resistance.2012

    • Author(s)
      Motonobu Nakamura, Ayumi Shirai, Osamu Yamazaki, Hideomi Yamada, Masashi Suzuki, Shoko Horita, Yukio Homma, George Seki
    • Organizer
      Annual Meeting of American Society of Nephrology
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-24591225
  • [Presentation] 上皮輸送と細胞内外pH調節機構におけるNa-HCO3共輸送体NBCe1の意義2012

    • Author(s)
      山崎修, 山田秀臣, 鈴木正志, 堀田晶子, 関常司
    • Organizer
      2012年度生理研研究会「粘膜防御における上皮膜輸送の役割とその破綻による疾病発症メカニズム」
    • Place of Presentation
      岡崎
    • Data Source
      KAKENHI-PROJECT-23390229
  • [Presentation] アンジオテンシン(Ang)IIのヒト近位尿細管特異的作用機序2012

    • Author(s)
      白井雅弓, 山崎修, 中村元信, 山田秀臣, 堀田晶子, 鈴木正志, 榎本 裕, 久米春喜, 本間之夫, Franz Hofmann, 関常司, 藤田敏郎
    • Organizer
      第55回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2012-06-01
    • Data Source
      KAKENHI-PROJECT-23390229
  • [Presentation] インスリンの近位尿細管輸送亢進作用はインスリン抵抗性でも保たれる2011

    • Author(s)
      中村元信, 山崎修, 白井雅弓, 山田秀臣, 堀田晶子, 鈴木正志, 榎本裕, 久米春喜, 本間之夫, 関常司, 藤田敏郎
    • Organizer
      第54回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-06-16
    • Data Source
      KAKENHI-PROJECT-23390229
  • [Presentation] アンジオテンシンIIのヒト近位尿細管作用におけるNO/sGC/cGMP経路の意義2011

    • Author(s)
      白井雅弓, 山崎修, 中村元信, 山田秀臣, 堀田晶子, 鈴木正志, 榎本裕, 久米春喜, 本間之夫, 関常司, 藤田敏郎
    • Organizer
      第54回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-06-15
    • Data Source
      KAKENHI-PROJECT-23390229
  • [Presentation] Na-HCO3トランスポーターNBCe1変異体ノックインマウスと尿細管性アシドーシス2011

    • Author(s)
      関常司, Sung-Sen Yang, 山崎修, 石黒洋, 山田秀臣, Shih-Hua Lin
    • Organizer
      第54回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-06-15
    • Data Source
      KAKENHI-PROJECT-23390229
  • [Presentation] 近位尿細管輸送の特性と調節機構2011

    • Author(s)
      関常司、山田秀臣、堀田晶子
    • Organizer
      第88回日本生理学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-03-30
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Presentation] NBCe1のL522P変異体はドミナントネガティブ効果を有する2011

    • Author(s)
      山崎修, 山田秀臣, 鈴木正志, 堀田晶子, 遠藤陽子, 白井雅弓, 中村元信, 関常司, 藤田敏郎
    • Organizer
      第54回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-06-16
    • Data Source
      KAKENHI-PROJECT-23390229
  • [Presentation] The cytosolic mutant L522P of NBCe1 has a dominant negative effect2011

    • Author(s)
      Yamazaki O, Yamada H, Suzuki M, Horita S, Nakamura M, Seki G, Fujita T
    • Organizer
      Annual Meeting of American Society of Nephrology
    • Place of Presentation
      フィラデルフィア(米国)(招待講演)
    • Year and Date
      2011-11-10
    • Data Source
      KAKENHI-PROJECT-23390229
  • [Presentation] The cytosolic mutant L522P of NBCe1 has a dominant negative effect2011

    • Author(s)
      Yamazaki O, Yamada H, Suzuki M, Horita S, Nakamura M, Seki G, Fujita T
    • Organizer
      Annual Meeting of American Society of Nephrology
    • Place of Presentation
      フィラデルフィア(米国)(招待講演)
    • Year and Date
      2011-11-10
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Presentation] NBCe1のL522P変異体はドミナントネガティブ効果を有する2011

    • Author(s)
      山崎修、山田秀臣、鈴木正志、堀田晶子、遠藤陽子、白井雅弓、中村元信、関常司、藤田敏郎
    • Organizer
      第54回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-06-16
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Presentation] Na-HCO3_トランスポーターNBCe1変異体ノックインマウスと尿細管性アシドーシス2011

    • Author(s)
      関常司、Sung-Sen Yang,山崎修、石黒洋、山田秀臣、Shih-Hua Lin
    • Organizer
      第54回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-06-15
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Presentation] NBCIW516XノックインマウスによるNBC1生理的機能の解析2010

    • Author(s)
      山崎修、関常司
    • Organizer
      第53回日本腎臓学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Presentation] NBC1W516Xノックインマウスを用いたNBC1の生理機能解析2010

    • Author(s)
      山崎修、Lo Yi-Fen、白井雅弓、山本明子、Song Ying、石黒洋、Yang Sung-Sun、Lin Shih-Hua、堀田晶子、山田秀臣、関常司,藤田敏郎
    • Organizer
      第5回トランスポーター研究会年会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-10
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Presentation] NBC1のSNP変異K558Rは機能低下を呈する2010

    • Author(s)
      山崎修、山田秀臣、堀田晶子、鈴木正志、関常司、藤田敏郎
    • Organizer
      第5回トランスポーター研究会年会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-10
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] NBC1W516XノックインマウスによるNBC1生理的機能の解析2010

    • Author(s)
      山崎修、Lo Yi-Fen、白井雅弓、山本明子、Song Ying、石黒洋、Yang Sung-Sun、Lin Shih-Hua、堀田晶子、山田秀臣、関常司、藤田敏郎
    • Organizer
      第53回日本腎臓学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] インスリン抵抗性におけるインスリンの近位尿細管作用2010

    • Author(s)
      堀田晶子、山崎修、山田秀臣、鈴木正志、遠藤陽子、関常司、藤田敏郎
    • Organizer
      第53回日本腎臓学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] Defective membrane expression of Na-HCO3 cotransporter NBCe1 is associated with migraine2010

    • Author(s)
      Suzuki M, Seki G, Horita S, Yamada H, Igarashi T, Fujita T
    • Organizer
      Annual Meeting of American Society of Nephrology
    • Place of Presentation
      Denver, USA
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Presentation] NBC1のSNP変異K558Rは機能低下型変異である2010

    • Author(s)
      山崎修、山田秀臣、堀田晶子、鈴木正志、関常司、藤田敏郎
    • Organizer
      第53回日本腎臓学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Presentation] NBC1W516XノックインマウスによるNBC1生理的機能の解析2010

    • Author(s)
      山崎修、Lo Yi-Fen、白井雅弓、山本明子、Song Ying、石黒洋、Yang Sung-Sun、Lin Shih-Hua、堀田晶子、山田秀臣、関常司、藤田敏郎
    • Organizer
      第53回日本腎臓学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Presentation] Defective membrane expression of Na-HCO3 cotransporter NBCe1 is associated with migraine.2010

    • Author(s)
      Suzuki M, Seki G, Horita S, Yamada H, Igarashi T, Fujita T
    • Organizer
      Annual Meeting of American Society of Nephrology.
    • Place of Presentation
      Denver, USA
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] NBC1のSNP変異K558Rは機能低下型変異である2010

    • Author(s)
      山崎修、山田秀臣、堀田晶子、鈴木正志、関常司、藤田敏郎
    • Organizer
      第53回日本腎臓学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] Functional analysis of SNP mutations leading to single amino acid substitution in NBCe1.2010

    • Author(s)
      Yamazaki O, Yamada H, Suzuki M, Horita S, Shirai A, Seki G, Fujita T
    • Organizer
      Annual Meeting of American Society of Nephrology.
    • Place of Presentation
      Denver, USA
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] NBC1 W516Xノックインマウスを用いたNBC1の生理機能解析2010

    • Author(s)
      山崎修、Lo Yi-Fen、白井雅弓、山本明子、Song Ying、石黒洋、Yang Sung-Sun、Lin Shih-Hua、堀田晶子、山田秀臣、関常司,藤田敏郎
    • Organizer
      第5回トランスポーター研究会年会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-10
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] アンジオテンシンIIはヒト近位尿細管NBC1活性を濃度依存的に亢進させる2010

    • Author(s)
      白井雅弓、山崎修、山田秀臣、堀田晶子、鈴木正志、榎本裕、久米春喜、本間之夫、関常司、藤田敏郎
    • Organizer
      第53回日本腎臓学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] NBC1 mutations showing defective plasma membrane expression cause pH dysregulation in astrocytes and are associated with migraine2009

    • Author(s)
      Suzuki M, Horita S, Van Paesschen W, Yamada H, Bergmans B, T Sekine T, Igarashi T, Seki G, Fujita T
    • Organizer
      ISN Frontier
    • Place of Presentation
      Florence, Italy
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Presentation] 近位尿細管性アシドーシス研究の現状と課題2009

    • Author(s)
      関常司、堀田晶子、鈴木正志、山田秀臣
    • Organizer
      第44回日本小児腎臓学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-06-26
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation]2009

    • Author(s)
      山田秀臣、永吉旭土、水谷顕洋、安東英明、御子柴克彦、堀田晶子、鈴木正志、関常司、藤田敏郎
    • Organizer
      第52回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-03
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] Identification of human brain type NBCl and its regulation by IRBIT2009

    • Author(s)
      山田秀臣、永吉旭土、水谷顕洋、安東英明、御子柴克彦、関常司、藤田敏郎
    • Organizer
      トランスポーター研究会、九州部会
    • Place of Presentation
      鹿児島大学
    • Year and Date
      2009-11-21
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] Functional comparison and mutational analysis of NBCl variants expressed in Xenopus Oocytes with IRBIT2009

    • Author(s)
      Hideomi Yamada, Shoko Horita, Masashi Suzuki, George Seki
    • Organizer
      国際腎臓学会
    • Place of Presentation
      イタリア、ミラノ
    • Year and Date
      2009-05-23
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] NBC1 mutations showing defective plasma membrane expression cause pH dysregulation in astrocytes and are associated with migraine.2009

    • Author(s)
      Suzuki M, Horita S, Van Paesschen W, Yamada H, Bergmans B, T Sekine T, Igarashi T, Seki G, Fujita T
    • Organizer
      ISN Frontier 2009
    • Place of Presentation
      Florence, Italy
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] Functional comparison of NBC1 variants expressed in Xenopus oocytes.2009

    • Author(s)
      Yamada H, Horita S, Suzuki M, Seki G
    • Organizer
      World Congress of Nephrology 2009.
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] NBC1のSNP変異体の解析2009

    • Author(s)
      山崎修、山田秀臣、堀田晶子、鈴木正志、関常司、藤田敏郎
    • Organizer
      第52回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] Identification of human brain type NBCl and its regulation by IRBIT2009

    • Author(s)
      Hideomi Yamada, Shoko Horita, Masashi Suzuki, George Seki
    • Organizer
      国際腎臓学会, ISN forefronts symposium
    • Place of Presentation
      イタリア、フィレンツェ
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] 近位尿細管性アシドーシス研究の現状と課題2009

    • Author(s)
      関常司、堀田晶子、鈴木正志、山田秀臣
    • Organizer
      第44回日本小児腎臓学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-06-26
    • Data Source
      KAKENHI-PROJECT-21591051
  • [Presentation] NBC1の病態生理学的意義とヴァリアント特異的調節機構2009

    • Author(s)
      関常司、山田秀臣、堀田晶子、鈴木正志、藤田敏郎
    • Organizer
      第52回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] ヒト脳型NBClはIRBITと機能的複合体を形成する2009

    • Author(s)
      山田秀臣、永吉旭土、重本隆一、水谷顕洋、黒田有希子、安東英明、御子柴克彦、関常司、藤田敏郎
    • Organizer
      日本腎臓学会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-03
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] Identification of human brain type NBC1 and its regulation by IRBIT.2009

    • Author(s)
      Yamada H, Nagayoshi A, Mizutani A, Ando H, Mikoshiba K, Horita S, Suzuki M, Seki G, Fujita T
    • Organizer
      ISN Frontier 2009
    • Place of Presentation
      Florence, Italy
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] NBC1C末欠損体はERに留まりdominant negative作用を有する2009

    • Author(s)
      鈴木正志、山田秀臣、堀田晶子、山崎修、関常司、藤田敏郎
    • Organizer
      第52回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] Physiology and pathophysiology of Na-HCO3 cotransporter NBC12008

    • Author(s)
      Seki G, H Yamada
    • Organizer
      第85回日本生理学会大会
    • Place of Presentation
      東京
    • Year and Date
      2008-03-25
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Presentation] Physiology and pathophysiology of Na-HCO_3 cotransporter NBC1.2008

    • Author(s)
      関常司, 山田秀臣
    • Organizer
      The Journal of Physiological Science Vol 58 Suppl, S22,日本生理学会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-03-25
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] PPARg/EGFR/ERK経路を介したチアゾリンの近位尿細管作用2008

    • Author(s)
      遠藤陽子、山田秀臣、李月紅、鈴木正志、山崎修、門脇孝、関常司、藤田敏郎
    • Organizer
      第51回日本腎臓学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-06-01
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Presentation] ヒト脳型NBC1の存在とIRBITによる活性化。IRBITアイソフォームによるpNBC1の活性調節2008

    • Author(s)
      山田秀臣、永吉旭土、水谷顕洋、安東英明、御子柴克彦、関常司、藤田敏郎
    • Organizer
      第51回日本腎臓学会学術総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-06-01
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] PPARg/EGFR/ERK経路を介したチアゾリンの近位尿細管作用2008

    • Author(s)
      遠藤陽子、山田秀臣、李月紅、鈴木正志、山崎修、門脇孝、関常司、藤田敏郎
    • Organizer
      第51回日本腎臓学会学術総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-06-01
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] 酸・塩基平衡関連分子の臨床2007

    • Author(s)
      関常司、堀田晶子、鈴木正志、山田秀臣
    • Organizer
      第37回日本腎臓学会東部会
    • Place of Presentation
      埼玉
    • Year and Date
      2007-10-06
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Presentation] 酸・塩基平衡関連分子の臨床2007

    • Author(s)
      関 常司
    • Organizer
      日本腎臓学会東部会
    • Place of Presentation
      大宮ソニックシティ
    • Year and Date
      2007-10-06
    • Data Source
      KAKENHI-PROJECT-19590934
  • [Presentation] The cytosolic mutant L522P of NBCe1 has a dominant negative effect

    • Author(s)
      Yamazaki O, Yamada H, Suzuki M, Horita S, Nakamura M, Seki G, Fujita T
    • Organizer
      Annual Meeting of American Society of Nephrology
    • Data Source
      KAKENHI-PROJECT-23390229
  • [Presentation] NO/sGC/cGMP/ERK pathway mediates a unique dose-dependent stimulation of human proximal transport by angiotensin II

    • Author(s)
      Shirai A, Yamazaki O, Nakamura M, Yamada H, Suzuki M, Horita S, Homma Y, Seki G
    • Organizer
      Annual Meeting of American Society of Nephrology
    • Data Source
      KAKENHI-PROJECT-23390229
  • [Presentation] Preserved expression of IRS2 mediates the stimulatory effect of insulin on renal proximal tubule sodium transport in insulin resistance

    • Author(s)
      Motonobu Nakamura, Osamu Yamazaki, Shoko Horita, Nobuhiko Sato, Hideomi Yamada, Masashi Suzuki, George Seki
    • Organizer
      American Society of Nephrology Kidney Week 2014
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2014-11-14 – 2014-11-16
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] 2Cl/H exchange function of CLC-5 is required for the maximal endosome acidification

    • Author(s)
      Nobuhiko Sato, Hideomi Yamada, Osamu Yamazaki, Shoko Horita, Masashi Suzuki, Motonobu Nakamura, Yoshitsugu Kaku, Daisuke Yamamoto, Akira Ashida, Takashi Sekine, George Seki
    • Organizer
      American Society of Nephrology Kidney Week 2014
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2014-11-14 – 2014-11-16
    • Data Source
      KAKENHI-PROJECT-25461241
  • [Presentation] Stimulatory effect of insulin on renal proximal Na transport is preserved in insulin resistance

    • Author(s)
      Nakamura M, Shirai A, Yamazaki O, Yamada H, Suzuki M, Horita S, Homma Y, Seki G
    • Organizer
      Annual Meeting of American Society of Nephrology
    • Data Source
      KAKENHI-PROJECT-23390229
  • [Presentation] Pioglitazone stimulates renal proximal transport through PPARg-dependent non-genomic pathway.

    • Author(s)
      Seki G, Endo Y, Yamada H, Horita S, Yamazaki O, Kadowaki T, Fujita T
    • Organizer
      Annual Meeting of American Society of Nephrology 2008.
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-20590971
  • [Presentation] Stimulatory effect of insulin on renal proximal Na transport is preserved in obesity-induced insulin resistant rats

    • Author(s)
      Nakamura M, Yamazaki O, Yamada H, Suzuki M, Horita S, Seki G, Fujita T
    • Organizer
      Annual Meeting of American Society of Nephrology
    • Data Source
      KAKENHI-PROJECT-23390229
  • [Presentation] NBC1 mutants showing defective plasma membrane expression are associated with migraine.

    • Author(s)
      Suzuki M, Horita S, Van Paesschen W, Yamada H, Bergmans B, T Sekine T, Igarashi T, Seki G, Fujita T
    • Organizer
      Annual Meeting of American Society of Nephrology 2008
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-20590971
  • []

  • []

  • []

  • []

  • []

  • []

  • 1.  TANIGUCHI Shigeo (50188380)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  YAMADA Hideomi (60396752)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 122 results
  • 3.  HORITA Shoko (20534895)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 89 results
  • 4.  NAKAO Akihide (10159056)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  WATANABE Tsuyoshi (80158641)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  NOIRI Eisei (00301820)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  SUZUKI Masashi (90595662)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 28 results
  • 8.  KUROKAWA Kiyoshi (30167390)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  NOSAKA Kazuo (70150274)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  MORIYAMA Nobuo (80143501)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 11.  鈴木 慶二 (70124675)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  高市 憲明 (00175423)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  ISHIZAKA Nobukazu (20270879)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SAITO Kan (60422292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TSUKAMOTO Kazuhisa (20251233)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  GOTO Jun (10211252)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  TOKUNAGA Katsushi (40163977)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  MIZUTANI Akihiro (30242861)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  KAWAAI Katsuhiro (00553653)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  HASHIMOTO Yoshiaki (40172879)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  TANAKA Yoshikazu (20292922)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  SHIMIZU Erika (50242144)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  AMANO Shiro (80193027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  ARIIZUMI Takashi (30286166)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 25.  高橋 祐二 (00372392)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  深川 雅史 (00211516)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  内田 俊也 (50151882)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  要 伸也 (60224581)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  本田 善一郎 (70238814)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  宮嶋 芳弘
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  東郷 真子
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  TOGO Masako
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  YAMADA Tomoko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  稲津 正人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  安東 英明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  浜崎 敬文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  中村 元信
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 38.  高野 幸路
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi