HORIBE Keizou 堀部敬三

… Alternative Names

堀部敬三ホリベケイゾウ

HORIBE Keizo 堀部敬三

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Researcher Number	30209308
Other IDs
Affiliation (Current)	2025: 独立行政法人国立病院機構(名古屋医療センター臨床研究センター), その他部局等, 臨床研究センター長
Affiliation (based on the past Project Information) *help	2016 – 2018: 独立行政法人国立病院機構(名古屋医療センター臨床研究センター), その他部局等, 臨床研究センター長 2012 – 2015: 独立行政法人国立病院機構(名古屋医療センター臨床研究センター), その他部局等, その他 2014: 名古屋医療センター臨床研究センター 2014: 独立行政法人国立病院機構名古屋医療センター, 臨床研究センター, 臨床研究センター長 2012: 独立行政法人国立病院機構名古屋医療センター, 臨床研究センター, センター長 … More 2011: 独立行政法人国立病院機構名古屋医療センター・臨床研究センター, センター長 2010: 独立行政法人国立病院機構名古屋医療センター, 臨床研究センター, センター長 2002: National Nagoya Hospital, Department of Pediatrics Associate Professor, 大学院・医学系研究科, 助教授 2001: 名古屋大学, 大学院・医学研究科, 助教授 2000: 名古屋大学, 大学院・医科系研究科, 助教授 1997 – 1998: 名古屋大学, 医学部, 助教授 1992 – 1996: 名古屋大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Pediatrics / Pediatrics / Nursing / Lifelong developmental nursing / Hematology
Keywords	Principal Investigator E2A-PBX1 / BCR-ABL / TEL-AML1 / Prognostic factor / Immunoglobulin heavy chain / Polymerase chain reaction / Minimal residual disease / Acute lymphoblastic leukemia / t(9;22) / t(1;19) … More / t(12;21) / CDRIII / 予後因子 / 免疫グロブリンH鎖遺伝子 / PCR法 / 微小残存腫瘍 / 急性リンパ性白血病 / Cytokine / Immunotherapy / Anti-ganglioside D2 antibody / Neuroblastoma / 抗ガングリオシドD2モノクローナル抗体 / 抗ガングリオシドD_2モノクローナル抗体 / サイトカイン / 免疫療法 / 抗ガングリオシドD2抗体 / 神経芽細胞腫 … More Except Principal Investigator DNA / MRD monitoring / minimal residual disease / ATRA-resistance / mutant PML-RARa / RARa / PML / all-trans retinoic acid / Acute promyelocytic leukemia / 染色体転座 / 急性前骨髄球性白血病 / 治療関連二次性白血病 / gammaH2aX / DNA損傷 / etoposide / gammaH2AX / ＤＮＡ損傷 / RB1 / 遺伝学的検査 / 家族性腫瘍 / 遺伝カウンセリング / 網膜芽細胞腫 / 遺伝性腫瘍 / レチノール酸耐性 / 定量PCR / MRDモニタリング / 急性前骨髄性白血病 / mutantPML / Acute promelocytic leukemia / MRD minitoring / mutant PML / acute promyelocytic leukemia / Chromosome / Pulse-field gel electrophoresis / Karyotype / Candida yeast / Opportunistic infection / カンジダ酵母 / 染色体 / 電気泳動 / 核型 / ガンジダ酵母 / 日和見感染 / encephalopathy / encephalitis / intrauterine infection / Cytomegalovirus / Herpes simplex encephalitis / Herpes simplex virus / PCR assay / 出生前診断 / 抗ウイルス剤 / ウイルスDNA / 早期診断 / 髄液 / エンテロウイルス / ウイルス性脳炎 / PCR / 胎内感染 / サイトメガロウイルス / 急性脳炎 / 定量的PCR法 / PCR法 / 単純ヘルペス脳炎 / 単純ヘルペスウイルス / 病弱児 / 特別支援教育 / 養護教諭 / 研修会 / 教員 / がんの子ども / プログラム構築 / 支援ツール / 学校教員 / 医療者 / クラスメート / 小児がん / 復学支援 / BCP-ALLモデル細胞 / 予後因子 / 抗がん剤感受性 / 小児急性リンパ性白血病 / RQ-PCR / MRD / ALL / 小児急性白血病 / 再発白血病 / 免疫関連遺伝子再構成 / 微小残存病変 / 小児白血病 / 転座メカニズム Less

An approach to establish pediatric hereditary cancer-related biomarkers applying DNA damage repair factors
- Principal Investigator
  
  Hattori Hiroyoshi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Hospital Organization Nagoya Medical Center
Exploration for therapeutic target using a novel prognostic factor IKZF1 targeting cells in childhood acute lymphoblastic leukemia
- Principal Investigator
  
  HATTORI Hiroyoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Hospital Organization Nagoya Medical Center
Basic Research to Establish the School Re-Entry Support Program for Children with Cancer
- Principal Investigator
  
  OMI SAKIE
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Lifelong developmental nursing
- Research Institution
  Gifu Shotoku Gakuen University
  Tenri Health Care University
STUDY OF MINIMAL RESIDUAL DISEASE MEASUREMENTS AND CLINICAL APPLICATION IN PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA
- Principal Investigator
  
  TSURUSAWA Masahito
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Aichi Medical University
Study on mechanism of ATRA-resistance and utility of MRD-monitoring in acute promyelocytic leukemia
- Principal Investigator
  
  IMAIZUMI Masue
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
白血病に関わる染色体転座部位の構造解析による転座メカニズム研究
- Principal Investigator
  
  直江知樹
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Prognostic significance of molecular detection of minimal residual disease in childhood acute lymphoblastic leukemiaPrincipal Investigator
- Principal Investigator
  
  HORIBE Keizo
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nagoya University
治療関連二次性白血病の発症にかかわる染色体転座機構の研究
- Principal Investigator
  
  直江知樹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
Basic study for clinical application of anti-ganglioside D2 monoclonal antibody against neuroblastomaPrincipal Investigator
- Principal Investigator
  
  HORIBE Keizo
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nagoya University
The study of opportunistic infection route and prevention on children with leukemia.
- Principal Investigator
  
  DOI Matsuko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Nursing
- Research Institution
  Gifu University
Research on molecular diagnosis of viral encephalitis in children -application to early diagnosis-
- Principal Investigator
  
  MORISHIMA Tuneo
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nagoya University

All 2018 2013 2012 2011

All Journal Article Presentation Book

[Book] 小児造血器腫瘍の診断の手引き2012
- Author(s)
  堀壽成,堀部敬三,鶴澤正仁編
- Publisher
  東京:日本医学館
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] Compound heterozygous TYK2 mutations underlie primary immunodeficiency with T-cell lymphopenia2018
- Author(s)
  Nemoto Michiko、Hattori Hiroyoshi、Maeda Naoko、Akita Nobuhiro、Muramatsu Hideki、Moritani Suzuko、Kawasaki Tomonori、Maejima Masami、Ode Hirotaka、Hachiya Atsuko、Sugiura Wataru、Yokomaku Yoshiyuki、Horibe Keizo、Iwatani Yasumasa
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 6956-6956
- DOI
  10.1038/s41598-018-25260-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04740, KAKENHI-PROJECT-16K08654, KAKENHI-PROJECT-17K08872, KAKENHI-PROJECT-18K05818, KAKENHI-PROJECT-15K09678
[Journal Article] Nilotinib monotherapy induced complete remission in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia resistant to imatinib and dasatinib.2013
- Author(s)
  Sekimizu M, Yamashita Y, Ueki H, Akita N, Hattori H, Maeda N, Horibe K.
- Journal Title
  
  Leuk Lymphoma
  
  Volume: Epub ahead of print Pages: 1-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591568
[Journal Article] Flow cytometric analysis of de novo acute lymphoblastic leukemia in childhood: report from the Japanese Pediatric Leukemia/Lymphoma Study Group.2011
- Author(s)
  Iwamoto S, Deguchi T, Ohta H, KiyokawaN, Tsurusawa M, Yamada T, Takase K, Fujimoto J, Hanada R, Hori H, HoribeK, Komada Y.
- Journal Title
  
  Int JHematol
  
  Volume: 94 Pages: 185-192
- NAID
  10029537148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Presentation] RB1遺伝学的検査による片眼性網膜芽細胞腫のリスク層別化2018
- Author(s)
  服部浩佳、森川真紀、久保田敏信、秋田直洋、関水匡大、市川瑞穂、前田尚子、堀部敬三.
- Organizer
  第24回日本家族性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09678
[Presentation] 網膜芽細胞腫に続発した二次性骨肉腫の2例2018
- Author(s)
  加藤結子、服部浩佳、秋田直洋、関水匡大、市川瑞穂、前田尚子、久保田敏信、小野学、二村昌樹、後藤雅彦、堀部敬三.
- Organizer
  第273回日本小児科学会東海地方会
- Data Source
  KAKENHI-PROJECT-15K09678
[Presentation] Risk Stratification of Unilateral Retinoblastoma Patients with the RB1 Genetic Testing.2018
- Author(s)
  Hattori H、Morikawa M、Taguchi I、Kubota T 、Akita N 、Sekimizu M 、Ichikawa M 、Maeda N、Horibe K.
- Organizer
  The 50th Congress of the International Society of Paediatric Oncology (SIOP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09678

1. TSURUSAWA Masahito (90172064)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. HATTORI Hiroyoshi (20624513)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 直江知樹 (50217634)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SAITO Yuko

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 大林包幸

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 市橋卓司

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 北村邦朗

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. HORI Toshinori (20308943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. OMI SAKIE (40329826)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAWAI Yoko (10249344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MORIGUCHI Kiyomi (80279356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MIYAGISHIMA Kyoko (60345832)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HIRAGA Kentaro (30379325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KINJO Yasuko (90369546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKAHASHIM Yumiko (80728147)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TANIGUCHI Emiko (20320939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HATANAKA Megumi (90600875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MORISHIMA Tuneo (90157892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. DOI Matsuko (00155615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TAMADA Akira (50252151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MAENO Hiroko (60252152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. IMAIZUMI Masue (40191895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. TSUCHIYA Shigeru (30124605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. IDE Hiroyuki (70022704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TSUKIMOTO Ichiro (70100964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 藤本孟男 (10037442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. YAMASHITA Yuka

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
28. FUKUDA Minoru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. Taguchi Iku

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
30. Tsutsumi Makiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. Kubota Toshinobu

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
32. Maeda Naoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
33. Morikawa Maki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
34. Sato Ko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 長谷川真司

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 宮島雄二

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. IWATANI Yasumasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HORIBE Keizou 堀部 敬三

堀部 敬三 ホリベ ケイゾウ

HORIBE Keizo 堀部 敬三

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Prognostic significance of molecular detection of minimal residual disease in childhood acute lymphoblastic leukemiaPrincipal Investigator

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Basic study for clinical application of anti-ganglioside D2 monoclonal antibody against neuroblastomaPrincipal Investigator

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[Book] 小児造血器腫瘍の診断の手引き2012

Author(s)

Publisher

Data Source

[Journal Article] Compound heterozygous TYK2 mutations underlie primary immunodeficiency with T-cell lymphopenia2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nilotinib monotherapy induced complete remission in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia resistant to imatinib and dasatinib.2013

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Journal Title

Data Source

[Journal Article] Flow cytometric analysis of de novo acute lymphoblastic leukemia in childhood: report from the Japanese Pediatric Leukemia/Lymphoma Study Group.2011

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NAID

Data Source

HORIBE Keizou 堀部敬三

堀部敬三ホリベケイゾウ

HORIBE Keizo 堀部敬三